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MIKI Takayuki  三木 隆幸

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三木 隆幸  ミキ タカユキ

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Researcher Number 00336405
Other IDs
Affiliation (Current) 2022: 札幌医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2020: 札幌医科大学, 医学部, 准教授
2012 – 2016: 札幌医科大学, 医学部, 准教授
2007 – 2011: Sapporo Medical University, 2^<nd> Dept. of Internal Medicine, Assistant Professor
2001 – 2006: 札幌医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine
Except Principal Investigator
Circulatory organs internal medicine / Cardiovascular medicine / Circulatory organs internal medicine / Basic Section 53020:Cardiology-related
Keywords
Principal Investigator
プレコンディショニング / スタニング / PKC-ε / AMP kinase / GLUT4 / 梗塞後心室リモデリング / プレコンデイショング
Except Principal Investigator
細胞死 / signal transduction / 細胞内情報伝達 … More / mitochondria / gap junction / コネキシン / cell death / connexin / protein kinase / preconditioning / 心筋細胞 / ミトコンドリア / necroptosis / autophagy / ネクロプトーシス / オートファジー / ギャップ結合 / protein kinase C / ischemia / myocardial infarction / 細胞シグナル / connexin-43 / G protein coupled receptor / β-subunit / 細胞内情報電達 / 活性酸素 / 透過性遷移孔 / ミトコンドリア透過性遷移孔 / グリコーゲン合成酵素キナーゼ3beta / グリコーゲン合成酵素キナーゼ3β / GSK-3β / 心筋虚血 / Cキナーゼ / myocardial ischemia / MAP kinase / ATP-sensitive K+ channel / ATP-sensitive potassium channel / コネキシン43 / 蛋白キナーゼ / 虚血障害 / プレコンディショニング / 細胞情報伝達 / シグナル伝達 / connexin43 / ischemic injury / 心不全 / RIP1 / mTORC1 / TFEB / heart failure / signal tranduction Less
  • Research Projects

    (9 results)
  • Research Products

    (89 results)
  • Co-Researchers

    (8 People)
  •  Cross-talk of cardiomyocyte necroptosis and autophagy in heart failure

    • Principal Investigator
      Tetsuji Miura
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Sapporo Medical University
  •  Novel therapeutic approach for heart failure by suppression of mitochondrial translocation of GSK-3beta

    • Principal Investigator
      Tanno Masaya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Sapporo Medical University
  •  Role of mitochondrial permeability transition in necroptosis of the cardiomyocyte

    • Principal Investigator
      Miura Tetsuji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Sapporo Medical University
  •  Protein kinases regulating the mitochondrial permeability transition pore

    • Principal Investigator
      TETSUJI Miura
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Sapporo Medical University
  •  Role of connexin-43 in protective signaling incardiomyocyte

    • Principal Investigator
      MIURA Tetsuji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Sapporo Medical University
  •  Roles of connexin-43 in cardiomyocyte tolerance against ischemic injury

    • Principal Investigator
      MIURA Tetsuji
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Sapporo Medical University
  •  Intracellular Signaling Mechanisms Regulating Functions and Expression of the Gap Junction in Ischemic Myocardium

    • Principal Investigator
      MIURA Tetsuji
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Sapporo Medical University
  •  PKC-ε活性化による心筋虚血再灌流障害の抑制の分子機構Principal Investigator

    • Principal Investigator
      三木 隆幸
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Sapporo Medical University
  •  Modification of gap junctions during myocardial ischemia and its significance in myocardial necrosis

    • Principal Investigator
      MIURA Tetsuji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Sapporo Medical University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2004 Other

All Journal Article Presentation

  • [Journal Article] Xanthine oxidoreductase-mediated injury is amplified by upregulated AMP deaminase in type 2 diabetic rat hearts under the condition of pressure overload.2021

    • Author(s)
      Igaki Yusuke、Tanno Masaya、Sato Tatsuya、Kouzu Hidemichi、Ogawa Toshifumi、Osanami Arata、Yano Toshiyuki、Kuno Atsushi、Miki Takayuki、Nakamura Takashi、Miura Tetsuji
    • Journal Title

      J Mol Cell Cardiol

      Volume: 154 Pages: 21-31

    • DOI

      10.1016/j.yjmcc.2021.01.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08522, KAKENHI-PROJECT-20K08452, KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-21K08110
  • [Journal Article] mTORC1 inhibition attenuates necroptosis through RIP1 inhibition-mediated TFEB activation.2020

    • Author(s)
      Abe K, Yano T, Tanno M, Miki T, Kuno A, Sato T, Kouzu H, Nakata K, Ohwada W, Kimura Y, Sugawara H, Shibata S, Igaki Y, Ino S, Miura T.
    • Journal Title

      Biochim Biophys Acta Mol Basis Dis

      Volume: 1865 Pages: 165552-165552

    • DOI

      10.1016/j.bbadis.2019.165552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-19K08544
  • [Journal Article] Distinct intra-mitochondrial localizations of pro-survival kinases and regulation of their functions by DUSP5 and PHLPP-12020

    • Author(s)
      Ohwada W, Tanno M, Yano T, Ong SB, Abe K, Sato T, Kuno A, Miki T, Sugawara H, Igaki Y, Miura T.
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

      Volume: 1866 Pages: 165851-165851

    • DOI

      10.1016/j.bbadis.2020.165851

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08544, KAKENHI-PROJECT-18K08079
  • [Journal Article] Translational regulation by miR-301b upregulates AMP deaminase in diabetic hearts2018

    • Author(s)
      Tatekoshi Y, Tanno M, Kouzu H, Abe K, Miki T, Kuno A, Yano T, Ishikawa S, Ohwada W, Sato T, Niinuma T, Suzuki H, Miura T.
    • Journal Title

      Journal of Molecular and Cellular Cardiology

      Volume: 119 Pages: 138-146

    • DOI

      10.1016/j.yjmcc.2018.05.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09584, KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-16K09505
  • [Journal Article] Empagliflozin normalizes the size and number of mitochondria and prevents reduction in mitochondrial size after myocardial infarction in diabetic hearts2018

    • Author(s)
      Mizuno M, Kuno A, Yano T, Miki T, Oshima H, Sato T, Nakata K, Kimura Y, Tanno M, Miura T
    • Journal Title

      Physiological Reports

      Volume: 6

    • DOI

      10.14814/phy2.13741

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-16K09505, KAKENHI-PROJECT-17K16016
  • [Journal Article] Does p53 Inhibition Suppress Myocardial Ischemia?Reperfusion Injury?2018

    • Author(s)
      Yano T, Abe K, Tanno M, Miki T, Kuno A, Miura T, Steenbergen C
    • Journal Title

      Journal of Cardiovascular Pharmacology and Therapeutics

      Volume: 印刷中 Pages: 350-357

    • DOI

      10.1177/1074248418763612

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09505, KAKENHI-PROJECT-18K08079
  • [Journal Article] Insufficient activation of Akt upon reperfusion because of its novel modification by reduced PP2A-B55α contributes to enlargement of infarct size by chronic kidney disease2017

    • Author(s)
      Toshiyuki Tobisawa*, Toshiyuki Yano*, Masaya Tanno, Takayuki Miki, Atsushi Kuno, Yukishige Kimura, Satoko Ishikawa, Hidemichi Kouzu, Keitaro Nishizawa, Hideaki Yoshida, Tetsuji Miura
    • Journal Title

      Basic Res Cardiol

      Volume: 112 Pages: 31-31

    • DOI

      10.1007/s00395-017-0621-6

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461133, KAKENHI-PROJECT-16K09505
  • [Journal Article] Chronic Treatment With an Erythropoietin Receptor Ligand Prevents Chronic Kidney Disease-Induced Enlargement of Myocardial Infarct Size.2016

    • Author(s)
      Nishizawa K, Yano T, Tanno M, Miki T, Kuno A, Tobisawa T, Ogasawara M, Muratsubaki S, Ohno K, Ishikawa S, Miura T.
    • Journal Title

      Hypertension

      Volume: 68 Pages: 697-706

    • DOI

      10.1161/hypertensionaha.116.07480

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461133, KAKENHI-PROJECT-16K09505
  • [Journal Article] Clinical impact of myocardial mTORC1 activation in nonischemic dilated cardiomyopathy.2016

    • Author(s)
      Yano T, Shimoshige S, Miki T, Tanno M, Mochizuki A, Fujito T, Yuda S, Muranaka A, Ogasawara M, Hashimoto A, Tsuchihashi K, Miura T
    • Journal Title

      J Mol Cell Cardiol

      Volume: 91 Pages: 6-9

    • DOI

      10.1016/j.yjmcc.2015.12.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461133
  • [Journal Article] Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats.2015

    • Author(s)
      Murase H, Kuno A, Miki T, Tanno M, Yano T, Kouzu H, Ishikawa S, Tobisawa T, Ogasawara M, Nishizawa K, Miura T.
    • Journal Title

      Cardiovasc Diabetol

      Volume: 14 Pages: 103-118

    • DOI

      10.1186/s12933-015-0264-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461133
  • [Journal Article] Excessive degradation of adenine nucleotides by up-regulated AMP deaminase underlies afterload-induced diastolic dysfunction in the type 2 diabetic heart.2015

    • Author(s)
      Hidemichi Kouzu, Takayuki Miki, Masaya Tanno, Atsushi Kuno, Toshiyuki Yano, Takahito Itoh, Tatsuya Sato, Daisuke Sunaga, Hiromichi Murase, Toshiyuki Tobisawa, Makoto Ogasawara, Satoko Ishikawa, Tetsuji Miura
    • Journal Title

      J Mol Cell Cardiol

      Volume: 80 Pages: 136-145

    • DOI

      10.1016/j.yjmcc.2015.01.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25860611, KAKENHI-PROJECT-26461132, KAKENHI-PROJECT-26461133
  • [Journal Article] Translocation of glycogen synthase kinase-3β (GSK-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (VDAC2).2014

    • Author(s)
      Tanno M, Kuno A, Ishikawa S, Miki T, Kouzu H, Yano T, Murase H, Tobisawa T, Ogasawara M, Horio Y, Miura T.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 289 Pages: 29285-29296

    • DOI

      10.1074/jbc.m114.563924

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461132, KAKENHI-PROJECT-26461133
  • [Journal Article] Type 2 diabetes induces subendocardium-predominant reduction in transient outward K^+ current with downregulation of Kv4.2 and KChIP22014

    • Author(s)
      Sato T, Kobayashi T, Kuno A, Miki T, Tanno M, Kouzu H, Itoh T, Ishikawa S, Kojima T, Miura T, Tohse N.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 306

    • DOI

      10.1152/ajpheart.00414.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Journal Article] Accelerated recovery of mitochondrial membrane potential by GSK-3β inactivation affords cardiomyocytes protection from oxidant-induced necrosis.2014

    • Author(s)
      Sunaga D, Tanno M, Kuno A, Ishikawa S, Ogasawara M, Yano T, Miki T, Miura T
    • Journal Title

      PLoS One

      Volume: 12

    • DOI

      10.1371/journal.pone.0112529

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461133
  • [Journal Article] Diabetic cardiomyopathy : pathophysiology and clinical features2013

    • Author(s)
      Miki T, Yuda S, Kouzu H, Miura T.
    • Journal Title

      Heart Fail Rev

      Volume: 18 Pages: 149-166

    • DOI

      10.1007/s10741-012-9313-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Journal Article] Role of connexin-43 in protective PI3K-Akt-GSK-3β signaling in cardiomyocytes.2012

    • Author(s)
      Ishikawa S, Kuno A, Tanno M, Miki T, Kouzu H, Itoh T, Sato T, Sunaga D, Murase H, Miura T
    • Journal Title

      American Journal of Physiology Heart and Circulatory Physiology

      Volume: 302

    • DOI

      10.1152/ajpheart.00940.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
  • [Journal Article] Role of ER stress in ventricular contractile dysfunction in type 2 diabetes.2012

    • Author(s)
      Takada A, Miki T, Kuno A, Kouzu H, Sunaga D, Itoh T, Tanno M, Yano T, Sato T, Ishikawa S, Miura T
    • Journal Title

      PLoS One

      Volume: 7

    • DOI

      10.1371/journal.pone.0039893

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
  • [Journal Article] Effects of diabetes on myocardial infarct size and cardioprotection by preconditioning and postconditioning2012

    • Author(s)
      Miki T, Itoh T, Sunaga D, Miura T.
    • Journal Title

      Cardiovasc Diabetol

      Volume: 11 Pages: 67-67

    • DOI

      10.1186/1475-2840-11-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Journal Article] Cytoprotective regulation of the mitochondrial permeability transition pore is impaired in type 2 diabetic Goto-Kakizaki rat hearts.2012

    • Author(s)
      Itoh T, Kouzu H, Miki T, Tanno M, Kuno A, Sato T, Sunaga D, Murase H, Miura T
    • Journal Title

      Journal of Molecular and Cellular Cardiology

      Volume: 53 Pages: 870-879

    • DOI

      10.1016/j.yjmcc.2012.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
  • [Journal Article] Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection2011

    • Author(s)
      Yano T, Miki T, Tanno M, Kuno A, Itoh T, Takada A, Sato T, Kouzu H, Shimamoto K and Miura T
    • Journal Title

      Hypertension

      Volume: 57 Pages: 110-115

    • DOI

      10.1161/hypertensionaha.110.158469

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
  • [Journal Article] Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection.2011

    • Author(s)
      Yano T, Miki T, Tanno M, Kuno A, Itoh T, Takada A, Sato T, Kouzu H, Shimamoto K, Miura T.
    • Journal Title

      Hypertension

      Volume: 57 Pages: 110-115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Journal Article] Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection.2011

    • Author(s)
      Yano T, Miki T, Tanno M, Kuno A, Itoh T, Takada A, Sato T, Kouzu H, Shimamoto K, Miura T.
    • Journal Title

      Hypertension 57

      Pages: 110-115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Erythropoietin (EPO) affords more potent cardioprotection by activation of distinct signaling to mitochondrial kinases compared with carbamylated EPO.2010

    • Author(s)
      Sato T, Tanno M. Miki T, Yano T, Sato T, Shimamoto K, Miura T.
    • Journal Title

      Cardiovasc Drugs Ther 24

      Pages: 401-408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Role of the gap junction in ischemic preconditioning in the heart.2010

    • Author(s)
      Miura T. Miki T. Yano T.
    • Journal Title

      Am J Physiol Heart Circ Physiol 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Angiotensin II type 1 receptor-mediated upregulation of calcineurin activity underlies impairment of cardioprotective signaling in diabetic hearts.2010

    • Author(s)
      Hotta H, Miura T. Miki T, Togashi N, Maeda T. Kim SJ, Tanno M Yano T, Kuno A, Itoh T, Satoh T, Terashima Y, Ishikawa S, Shimamoto K.
    • Journal Title

      Circ Res 106

      Pages: 129-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Roles of phospho-GSK-3β in myocardial protection afforded by activation of the mitochondrial K ATP channel.2010

    • Author(s)
      Terashima Y, Sato T, Yano T, Maas O, Itoh T, Miki T, Tanno M, Kuno A, Shimamoto K, Miura T.
    • Journal Title

      J Mol Cell Cardiol 49

      Pages: 762-770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Endoplasmic reticulum stress in diabetic hearts abolishes erythropoietin-induced myocardial protection by impairment of phospho-glycogen synthase kinase-3β-mediated suppression of mitochondrial permeability transition.2009

    • Author(s)
      Miki T Miura T, Hotta H, Tanno M, Yano T, Sato T, Terashima Y, Takada A, Ishikawa S, Shimamoto K.
    • Journal Title

      Diabetes 58

      Pages: 2863-2872

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Drug development targeting the glycogen synthase kinase-3β (GSK-3β)-mediated signal transduction pathway : role of GSK-3β in myocardial protection against ischemia/reperfusion injury.2009

    • Author(s)
      Miura T, Nishihara M, Miki T.
    • Journal Title

      J Pharmacol Sci 109

      Pages: 162-167

    • NAID

      10025734088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] GSK-3β, a therapeutic target for cardiornyocyte protection.2009

    • Author(s)
      Miura T Miki T.
    • Journal Title

      Circ J 73

      Pages: 1184-1192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Roles of Cx43-associated protein kinases in suppression of gap junction-mediated chemical coupling by ischemic preconditioning.2009

    • Author(s)
      Naitoh K, Yano T, Miura T, Itoh T, Miki T Tanno M Sato T, Hotta H, Terashima Y, Shimamoto K.
    • Journal Title

      Am J Physiol Heart Circ Physiol 296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Limitation of infarct size by erythropoietin is associated with translocation of Akt to the mitochondria after reperfusion.2008

    • Author(s)
      Kobayashi H, Miura T. Ishida H, Miki T. Tanno M Yano T, Sato T, Hotta H, Shimamoto K.
    • Journal Title

      Clin Exp Pharmacol Physiol 35

      Pages: 812-819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Limitation of myocardial infarct size in the clinical setting : current status and challenges in translating animal experiments into clinical therapy.2008

    • Author(s)
      Miura T, Miki T.
    • Journal Title

      Basic Res Cardiol 103

      Pages: 501-513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Ser9 phosphorylation of mitochondrial GSK-3β is a primary mechanism of cardiomyocyte protection by erythropoietin against oxidant-induced apoptosis.2008

    • Author(s)
      Ohori K, Miura T, Tanno M, Miki T, Sato T, Ishikawa S, Horio Y, Shimamoto K.
    • Journal Title

      Am J Physiol Heart Circ Physiol 295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Journal Article] Ischemic preconditioning activate AMPK in a PKC-dependent manner and induces GLUT4 up-regulation in the late phase of cardioprotection.2004

    • Author(s)
      Nishino Y, Miura T, Miki T, et al.
    • Journal Title

      Cardiovasc Res 64

      Pages: 610-619

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590702
  • [Journal Article] Ischemic preconditioning activates AMPK in a PKC-dependent manner and induces GLUT4 up-regulation in the late phase of cardioprotection.2004

    • Author(s)
      Nishino Y, Miura T, Miki T, et al.
    • Journal Title

      Cardiovascular Research 61(3)

      Pages: 610-619

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590702
  • [Presentation] Phosphorylated MLKL, an Executor of Necroptosis, Localized in the Nucleus and Intercalated Disc Plays Distinct Roles in Nonischemic Dilated Cardiomyopathy.2020

    • Author(s)
      Fujita Y, Yano T, Nagano N, Nishikawa R, Kamiyama N, Fujito T, Mochizuki A, Koyama M, Kouzu H, Muranaka A, Nagahara D, Tannno M, Miki T, Miura T.
    • Organizer
      第84回日本循環器学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08079
  • [Presentation] Novel regulation of cardiac branched-chain amino acid metabolism through AMP deaminase: A possible therapeutic target for diabetic cardiomyopathy.2020

    • Author(s)
      Ogawa T, Kouzu H, Tatekoshi Y, Osanami A, Oshima H, Mizuno M, Kuno A, Igaki Y, Sugawara H, Fujita Y, Sato T, Yano T, Tanno M, Miki T, Miura T.
    • Organizer
      European Society of Cardiology Congress 2020
    • Data Source
      KAKENHI-PROJECT-18K08079
  • [Presentation] Activation of necroptotic pasthway by downregulated caspase-8 expression is associated with progression of left ventricular remodeling in nonischemic dilated cardiomyopathy.2019

    • Author(s)
      Fujita Y, Yano T, Abe K, Nagano N, Kamiyama N, Fujito T, Mochizuki A, Koyama M, Kouzu H, Muranaka A, Nagahara D, Tanno M, Miki T, Miura T
    • Organizer
      ESC congress 2019. Paris, France.
    • Data Source
      KAKENHI-PROJECT-18K08079
  • [Presentation] mTORC1 suppresses cardiomyocyte necroptosis through autophagy and RIP1 inhibition2018

    • Author(s)
      Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Miura T.
    • Organizer
      日本循環器学会基礎医学フォーラム
    • Data Source
      KAKENHI-PROJECT-18K08079
  • [Presentation] Inhibition of mTORC1 supresses necroptosis of cardiomyocytes in a p70S6K-independent mechanism by suppression of p62-RIP1 interaction.2018

    • Author(s)
      Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Miura T.
    • Organizer
      日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08079
  • [Presentation] mTORC1 inhibition suppresses necroptosis through restroration of autophagic flux by inhibitory phosphorylation of RIP1 in cardiomyocytes.2018

    • Author(s)
      Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Mizuno M, Miura T.
    • Organizer
      European Society of Cardiology Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08079
  • [Presentation] Crosstalk between Aberrant mTORC1 Activation and Necroptotic Pathway: a Novel Therapeutic Target in Ischemic Heart Disease2018

    • Author(s)
      Yano T, Abe K, Ogasawara M, Kuno A, Tanno M, Miki T, Miura T.
    • Organizer
      日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08079
  • [Presentation] Increased activity of AMP deaminase by decreased interaction with PGM1 and depletion of F1,6P: a novel mechanism of diabetic cardiomyopathy2016

    • Author(s)
      Y. Tatekoshi, H. Kouzu, M. Tanno, A. Kuno, S. Ishikawa, T. Yano, T. Miki , M. Ogasawara, T. Tobisawa, K. Ono, S. Muratsubaki, K. Nishizawa, T. Miura
    • Organizer
      22nd Congress of International Society for Heart Research
    • Place of Presentation
      Buenos Aires, Argentina
    • Year and Date
      2016-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461132
  • [Presentation] Sequestration of p62 by RIP1 promotes necroptosis through suppression of autophagic flux in cardiomyocytes; a novel cross-talk between autophagy and necroptosis2016

    • Author(s)
      Yano T, Ogasawara M, Miki T, Tanno M, Kuno A, Ohno K, Nishizawa K, Owada W, Mizuno M, Suwawara H, Tatekoshi Y, Nakata K, Ishikawa S, Miura T
    • Organizer
      European Society of Cardiology Congress 2016
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2016-08-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461133
  • [Presentation] Excessive ROS production in mitochondria switches off protective mitochondrial kinase signaling.2016

    • Author(s)
      Tanno M, Ohwada W, Yano T, Miki T, Kuno A, Ishikawa S, Tatekoshi Y, Nishizawa K, Mizuno M, Miura T.
    • Organizer
      4th Congress of Frontiers in Cardiovascular Biology
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2016-07-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461132
  • [Presentation] Excessive ROS production in mitochondria switches off protective mitochondrial kinase signaling2016

    • Author(s)
      Owada W, Tanno M, Yano T, Miki T, Kuno A, Ishikawa S, Tatekoshi Y, Nishizawa K, Mizuno M, Miura T.
    • Organizer
      4th Congress of Frontiers in CardioVascular Biology, European Society of Cardiology
    • Place of Presentation
      Florence, bItaly
    • Year and Date
      2016-07-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461132
  • [Presentation] ROS-induced mitochondrial translocation of phosphatases cancelscell-protective signals activated by phosphorylation of mitochondrial protective kinases2016

    • Author(s)
      Ohwada W, Tanno M, Yano T, Kuno A, Miki T, Ishikawa S, Tatekoshi Y, Abe K, Ohno K, Mizuno M, Nakata K, Miura T.
    • Organizer
      89th Scientific Session of American Heart Association
    • Place of Presentation
      New Orleans, U.S.A.
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461132
  • [Presentation] Depletion of fructose 1,6-diphosphate but not post-translational modification plays a major role in activation of AMP deaminase in diabetic hearts: a novel mechanism for diabetic cardiomyopathy.2016

    • Author(s)
      Y. Tatekoshi, M. Tanno, A. Kuno, S. Ishikawa, T. Yano, T. Miki, M. Ogasawara, T. Tobisawa, K. Ohno, S. Muratsubaki, K. Nishizawa, T. Miura
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2016-03-18
    • Data Source
      KAKENHI-PROJECT-26461132
  • [Presentation] Intramolecular inhibition of Ser473 phosphorylation by up-regulated Thr308 phosphorylation in Akt cotributes to enlargement of infarct size by chronic renal failure.2015

    • Author(s)
      T. Tobisawa, T. Yano, T. Miki, M. Tanno, A. Kuno, H. Kouzu, M. Ogasawara, S. Muratsubaki, K. Ohno, K. Nishizawa, M. Mizuno, W. Owada, S. Ishikawa, T. Miura.
    • Organizer
      88th Scientific Session of American Heart Association:
    • Place of Presentation
      Orlando, U.S.A.
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461132
  • [Presentation] Continuous erythropoietin receptor activation reverses increased myocardial susceptibility to ischemia/reperfusion injury in chronic renal failure.2015

    • Author(s)
      K. Nishizawa, T. Yano, T. Miki, M. Tanno, A. Kuno, H. Kouzu, T. Tobisawa, M. Mizuno, H. Sugawara, T. Miura.
    • Organizer
      37th Congress of the European Society of Cardiology
    • Place of Presentation
      London, UK
    • Year and Date
      2015-08-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461132
  • [Presentation] Suppression of Autophagic Flux by Sequestration of p62 Promotes RIP1-mediated Necroptosis in Cardiomyocytes2015

    • Author(s)
      Makoto Ogasawara; Toshiyuki Yano; Takayuki Miki; Masaya Tanno; Atsushi Kuno; Hidemichi Kouzu; Toshiyuki Tobisawa; Shingo Muratsubaki; Kohei Ohno; Keitaro Nishizawa; Satoko Ishikawa; Tetsuji Miura
    • Organizer
      Scientific Sessions of the American Heart Association 2015
    • Place of Presentation
      Orlando, USA
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461133
  • [Presentation] Acceleration of mPTP re-closure after oxidant stress by mitochondrial K_<ATP> channel activation is achieved by suppression of residual ROS production2014

    • Author(s)
      Ogasawara M, Kuno A, Ishikawa S, Tobisawa T, Kouzu H, Yano T, Miki T, Miura T
    • Organizer
      The 78^<th> Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Acceleration of mPTP Re-closure after Oxidant Stress by Mitochondrial KATP Channel Activation is Achieved by Suppression of Residual ROS Production2014

    • Author(s)
      Ogasawara M, Kuno A, Ishikawa S, Tobisawa T, Kouzu H, Yano T, Miki T, and Miura T.
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Type 2 diabetes induces ventricular electrical remodeling with a transmural gradient2013

    • Author(s)
      Tobisawa T, Sato T, Yuda S, Miki T, Tanno M, Kuno A, Kobayashi T, Akasaka H, Tohse N, Miura T
    • Organizer
      European Society of Cardiology Congress 2013
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Interaction of cyclophilin D with inorganic phosphate carrier during ischemia determines threshold for mPTP opening and reperfusion-induced cell necrosis2013

    • Author(s)
      Ito T, Kouzu H, Miki T, Tanno M, Kuno A, Sato T, Sunaga D, Murase H, Ishikawa S, Miura T
    • Organizer
      The 77^<th> Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Mechanisms underlying mitochondrial translocation of GSK-3beta, a crucial induces of mitochondrial permeability transition : GSK-3beta activity, interaction with VDAC2 and a mitochondrial targeting sequence2013

    • Author(s)
      Tanno M, Kuno A, Ishikawa S, Ogasawara M, Tobisawa T, Murase H, Sato T, Kouzu H, Miki T, Miura T
    • Organizer
      American Heart Association BCVS
    • Place of Presentation
      Las Vegas, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Mechanisms Underlying Mitochondrial Translocation Of GSK-3β, A Crucial Inducer Of Mitochondrial Permeability Transition: GSK-3β Activity, Interaction With VDAC2 And A Mitochondrial Targeting Sequence.2013

    • Author(s)
      Tanno M, Kuno A, Ishikawa S, Ogasawara M, Tobisawa T, Murase H, Sato T, Kouzu H, Miki T, and Miura T
    • Organizer
      American Heart Association BCVS 2013
    • Place of Presentation
      Las Vegas, Nevada, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Interaction with VDAC2 promotes mitochondrial translocation of GSK-3beta in a kinase activity-dependent manner and induces cell death.2013

    • Author(s)
      Masaya Tanno,Takayuki Miki, Atsushi Kuno , Hidemichi Kouzu, Takahito Itoh , Tatsuya Satoh, Satoko Ishikawa, Daisuke Sunaga, Tetsuji Miura
    • Organizer
      The 77th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Activation of the glucagon-like peptide-1 receptor restores myocardial autophagic flux and reduced mortality after myocardial infarction in diabetic rats2013

    • Author(s)
      Murase H, Kuno A, Miki T, Tanno M, Yano T, Kouzu H, Tobisawa T, Ogasawara M, Ishikawa S, Miura T
    • Organizer
      Scientific Sessions 2013, the American Heart Association
    • Place of Presentation
      Dallas, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Activation of the Glucagon-Like Peptide-1 Receptor Restores Myocardial Autophagic Flux and Reduces Mortality After Myocardial Infarction in Diabetic Rats2013

    • Author(s)
      Murase H, Kuno A, Miki T, Tanno M, Yano T, Kouzu H, Tobisawa T, Ogasawara M, Ishikawa S, and Miura T.
    • Organizer
      American Heart Association Scientific Sessions 2013
    • Place of Presentation
      Dallas, Texas, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Interaction of cyclophilin D with inorganic phosphate carrier during ischemia determines threshold for mPTP opening and reperfusion-induced cell necrosis.2013

    • Author(s)
      Takahito Ito,Hidemichi Kouzu , Takayuki Miki , Masaya Tanno , Atsushi Kuno , Tatsuya Satoh , Daisuke Sunaga , Hiromichi Murase , Satoko Ishikawa , Tetsuji Miura
    • Organizer
      The 77th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Interaction with VDAC2 promotes mitochondrial traslocation of GSK-3beta in a kinase activity-dependent manner and induces cell death2013

    • Author(s)
      Tanno M, Miki T, Kuno A, Kouzu H, Itoh T, Sato T, Ishikawa S, Sunaga D, Miura
    • Organizer
      The 77^<th> Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Activation of the mitochondrial ATP-sensitive potassium channel achieves cell protection by promoting re-closure of the mPTP via suppression of GSK-3beta - complex III interaction2013

    • Author(s)
      Sunaga D, Tanno M, Miki T, Kuno A, Kouzu H, Sato T, Ishikawa S, Ogasawara M, Tobisawa T, and Miura T
    • Organizer
      European Society of Cardiology Congress 2013
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Facilitated re-closure of the mitochondrial permeability transition pore underlies protection of cardiomyocytes from ROS-induced necrosis by activation of the mitochondrial ATP-sensitive K^+ channel2012

    • Author(s)
      Suanga D, Kuno A, Ishikawa S, Miki T, Tanno M, Kouzu H, Itoh T, Sato T, Murase H, Miura T
    • Organizer
      Scientific Sessions 2012, the American Heart Association
    • Place of Presentation
      Los Angeles, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Titin-isoform shift may underlie distinct ventricular responses to pressure and volume overloads in type 2 diabetic heart2012

    • Author(s)
      Kouzu H, Kuno A, Miki T, Tanno M, Itoh T, Sato T, Sunaga D, Murase H, Miura T
    • Organizer
      Scientific Sessions 2012, the American Heart Association
    • Place of Presentation
      Los Angeles, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Facilitated Re-Closure of the Mitochondrial Permeability Transition Pore Underlies Protection of Cardiomyocytes from ROS-Induced Necrosis by Activation of the Mitochondrial ATP-Sensitive K+ Channel2012

    • Author(s)
      Daisuke Sunaga, Atsushi Kuno, Satoko Ishikawa, Takayuki Miki, Masaya Tannno, Hidemichi Kouzu, Takahito Itoh, Tatsuya Sato, Hiromichi Murase, and Tetsuji Miura
    • Organizer
      Scientific Sessions 2012, the American Heart Assocaition
    • Place of Presentation
      Los Angeles, CA, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Titin-isoform Shift May Underlie Distinct Ventricular Responses to Pressure and Volume Overloads in Type 2 Diabetic Heart2012

    • Author(s)
      Hidemichi Kouzu, Atsushi Kuno, Takayuki Miki, Masaya Tanno, Takahito Itoh, Tatsuya Sato, Daisuke Sunaga, Hiromichi Murase, and Tetsuji Miura
    • Organizer
      Scientific Sessions 2012, the American Heart Assocaition
    • Place of Presentation
      Los Angeles, CA, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] UPR In Endoplasmic Reticulum vs. UPR In Mitochondria In Diabetic Myocardium: Which Is Responsible For Deficient Regulation Of Mitochondrial Permeability Transition Pores?2011

    • Author(s)
      Itoh T, Kouzu H, Miki T, Tanno T, Kuno A, Sato T, Sunaga D, Ishikawa S, Miura T
    • Organizer
      American Heart Association Scientific Sessions 2011
    • Place of Presentation
      Orlando, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] UPR in endoplasmic reticulum vs. in mitochondria in diabetic myocardium : which is responsible for deficient regulation of mitochondrial permeability transition pores?2011

    • Author(s)
      Itoh T, Kouzu H, Miki T, Tanno M, Kuno A, Sato T, Sunaga D, Ishikawa S, Miura
    • Organizer
      Scientific Sessions 2011, the American Heart Association
    • Place of Presentation
      Orlando, USA
    • Data Source
      KAKENHI-PROJECT-23591086
  • [Presentation] Increased ER stress is a fundamental mechanism for impairment of cardioprotective signaling in type 2 diabetes.2010

    • Author(s)
      Kouzu H, Itoh T, Miki T. Tanno M, Yano Y, Sato T, Takada A, Sunaga D, Miura T.
    • Organizer
      83rd Scientific Sessions of American Heart Association.
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Ventricular dysfunction and blunted response to adrenergic stimulation in obese type 2 diabetes predispose to fatal heart failure after infarction : Possible involvement of microRNA-1 down-regulation.2010

    • Author(s)
      Takada A, Miki T Tanno M, Suzuki H, Yano T, Kuno A, Itoh T, Sato T, Miura T.
    • Organizer
      83rd Scientific Sessions of American Heart Association.
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Mitochondria is a critical compartment for phospho-GSK-3β to afford cytoprotection against ischemia/reperfusion injury.2010

    • Author(s)
      Sato T, Miura T, Tanno M, Miki T, Takada A, Itch T, Shimamoto K.
    • Organizer
      20th World Congress of the International Society for Heart Research.
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Connexin43-dependent mitochondrial GSK-3β phosphorylation in protection of cardiomyocyte against necrosis.2010

    • Author(s)
      Ishikawa S, Miki T, Tanno M, Miura T.
    • Organizer
      20th World Congress of the International Society for Heart Research.
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Glycogen synthase kinase-3β as a therapeutic target for cardiomyocyte protection.2010

    • Author(s)
      Miura T. Miki T, Shimamoto K.
    • Organizer
      20th World Congress of the International Society for Heart Research.
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Connexin-43 contributes to transmission of MitoK_ATP channel-derived redox signal to Akt-GSK-3β pathway in cardiomyocyte protection afforded by G protein-coupled receptors.2010

    • Author(s)
      Ishikawa S, Kuno A, Miki T, Tanno T. Yano T, Kouzu H, Sato T, Sunaga D, Miura T.
    • Organizer
      83rd Scientific Sessions of American Heart Association.
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Role of GSK-3β in negative regulation of the mPTPs by the mitochondrial K_ATP channel.2010

    • Author(s)
      Itch T, Terashima Y, Miki T, Miura T, Shimamoto K.
    • Organizer
      20th World Congress of the International Society for Heart Research.
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Jak2-mediated cardioprotective signaling is impaired in diabetic hearts by AT_1 receptormediated up-regulation of calcineurin.2009

    • Author(s)
      Miura T, Hotta H, Miki T, Yano T, Ishikawa S, Shimamoto K.
    • Organizer
      31st Congress of the European Society of Cardiology.
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Enhanced ANT-cyclophilin-D interaction underlies reduced anti-infarct tolerance and loss of protective response to erythropoietin in hypertensive hypertrophied hearts.2009

    • Author(s)
      Miki T. Yano T, Miura T, Tanno M. Shimamoto K.
    • Organizer
      31st Congress of the European Society of Cardiology.
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Role of GSK-3β in negative regulation of mitochondrial permeability transition pore by the mitochondrial K_ATP channel.2009

    • Author(s)
      Miura T, Terashima Y, Maas O, Miki T, Tanno M, Ishikawa S, Shimamoto K.
    • Organizer
      31st Congress of the European Society of Cardiology.
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] ER stress contributes to dysregulation of GSK-3β-medaited suppression of mitochondrial permeability transition in diabetic hearts.2008

    • Author(s)
      Takayuki Miki, et al.
    • Organizer
      81^<st> Scientific Sessions of American Heart Association
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2008-11-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590781
  • [Presentation] ER stress contributes to dysregulation of GSK-3β-mediated suppression of mitochondrial permeability transition in diabetic hearts.2008

    • Author(s)
      Miki T, Tanno M, Kuno A, Yano T, Sato T, Hotta H, Ichikawa S, Miura T.
    • Organizer
      81st Scientific Sessions of American Heart Association.
    • Place of Presentation
      New Orleans, USA.
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Connexin43-dependent and-independent mechanisms of mitochondrial GSK-3β phosphorylation in protection of cardiomyocyte against necrosis.2008

    • Author(s)
      Ishikawa S, Miura T, Tanno M, Kuno A, Sato T, Hotta H, Terashima Y, Miki T.
    • Organizer
      81st Scientific Sessions of American Heart Association.
    • Place of Presentation
      New Orleans, USA.
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] ES stress contributes to dysregulation of GSK-3β-medaited suppression of mitochondrial permeability transition in diabetic hearts.2008

    • Author(s)
      Takayuki Miki, et al.
    • Organizer
      81^<st> Scientific Sessions of American Heart Association
    • Place of Presentation
      New Orleans, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590781
  • [Presentation] Activation of a protein deacetylase, SIRTI, by Resveratol suppresses progression of heart failure and improves survival by up-regulation of Mn-SOD.2008

    • Author(s)
      Tanno M Kuno A, Miki T. Miura T. Horio Y, Shimamoto K.
    • Organizer
      81st Scientific Sessions of American Heart Association.
    • Place of Presentation
      New Orleans, USA.
    • Data Source
      KAKENHI-PROJECT-20590870
  • [Presentation] Modulation of Akt/GSK-3β signaling and mitochondrial GSK-3βby ER stress underlies failure of erythropoietin to protect diabetic hearts.2007

    • Author(s)
      Takayuki Miki, et al.
    • Organizer
      80^<th> Scientific Sessions of American Heart Association
    • Place of Presentation
      Orlando, USA
    • Year and Date
      2007-11-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590781
  • [Presentation] Modification of Akt/GSK-3b signaling and mitochondrial GSK-3β by ER stress underlies failure of erythropoietin to protect diabetic hearts.2007

    • Author(s)
      Takayuki Miki
    • Organizer
      American Heart Association Scientific Sessions 2007
    • Place of Presentation
      Orlando, Florida, USA
    • Year and Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-18590781
  • [Presentation] Modulation of Akt/GSK-3β signaling and mitochondrial GSK-3β by ER stress underlies failure of erythropoietin to protect diabetic hea2007

    • Author(s)
      Takayuki Miki, et al.
    • Organizer
      80^<th> Scientific Sessions of American Heart Association
    • Place of Presentation
      Orlando, USA.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590781
  • [Presentation] Mitochondrial translocation of GSK-3β, a trigger of mitochondrial permeability transition, is mediated by its N-terminal domain and promoted by interaction with VDAC2.

    • Author(s)
      Tanno M, Ishikawa S, Miki T, Kuno A, Kouzu H, Yano T, Miura T
    • Organizer
      Frontiers in Cardiovascular Biology, 3rd meeting of the ESC council on basic cardiovascular science
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2014-07-04 – 2014-07-06
    • Data Source
      KAKENHI-PROJECT-26461132
  • [Presentation] Accumulation of p62 by dysregulation of autophagy induces RIP1-dependent necroptosis in cardiomyocytes: a novel interplay between autophagy and necroptosis.

    • Author(s)
      Ogasawara M, Yano T, Miki T, Tanno M, Kuno A, Kouzu H, Murase H, Tobisawa T, Muratsubaki S, Nishizawa K, Mizuno M, Ishikawa S, Miura T.
    • Organizer
      American Heart Association, Scientific Sessions 2014
    • Place of Presentation
      Chicago, Illinois, USA
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-26461133
  • 1.  MIURA Tetsuji (90199951)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 84 results
  • 2.  TANNO Masaya (00398322)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 69 results
  • 3.  UNO Kikuya (50305223)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  SAKAMOTO Jun (40336392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  矢野 俊之 (40444913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 6.  KUNO Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 7.  佐藤 達也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  神津 英至
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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