HASHIKAWA Tomoko 橋川智子

Researcher Number	00362682
Other IDs
Affiliation (based on the past Project Information) *help	2007 – 2012: Osaka University, Graduate School ofDentistry, Assistant Professor 2011: Osaka University, 歯学研究科(研究院), 助教 2005 – 2006: 大阪大学, 大学院歯学研究科, 助手 2003 – 2005: 大阪大学, 大学院・歯学研究科, 助手
Review Section/Research Field	Principal Investigator Periodontal dentistry Except Principal Investigator Periodontal dentistry / Conservative dentistry / Dental engineering/Regenerative dentistry
Keywords	Principal Investigator 実験的歯周病モデル / アディポネクチン / 炎症 / 脂肪組織 / アディポカイン / 幹細胞 / 再生医学 / プリンヌクレオシド / 歯周組織再生療法 / 細胞移入 … More / 歯周組織再生 / 脂肪組織由来幹細胞 / 歯周外科学 / アテノシンデアミナーゼ / CD26 / アデノシンデアミナーゼ / アデノシン … More Except Principal Investigator 歯根膜細胞 / 歯周組織再生 / FGF-2 / PLAP-1 / ヒアルロン酸 / 細胞遊走 / トランスクリプトーム / 歯肉線維芽細胞 / periodontal ligament stem cells / DNA chip analysis / オリゴDNAチップ / 硬組織形成分化 / IDI / 歯根膜幹細胞 / DNAチップ解析 / 歯根膜特異的分子PLAP-1 / transcriptome / genome science / periodontal tissue regeneration / periodontal tissue / periodontal ligament / 完全長cDNAライブラリ / ゲノム科学 / 歯周組織 / 歯根膜 / basic fibroblast growth factor / cell migration / heparan sulfate / regenerative therapy / hyaluronan / periodontal ligament cells / pulp cells / dentin-pulp complex / ALPase活性 / 石灰化 / 修復象牙質 / 覆髄剤 / ヒト歯髄細胞 / シンデカン / ヒアルロン酸合成酵素 / 創傷治癒 / 塩基性繊維芽細胞増殖因子 / 塩基性線維芽細胞増殖因子 / ヘパラン硫酸 / 組織再生療法 / 歯髄細胞 / 象牙質・歯髄複合体 / 細胞移植 / 歯周組織再生療法 / akt / PI3K / 再生歯学 / 歯根膜組織 / DNAメチル化 / エピジェネティクス / 歯周組織幹細胞 / CD54 / スフィンゴシン-1-リン酸 / ICAK-1 / IL-6 / スフィンゴシン1リン酸 / リゾリン脂質 / 歯周免疫機能学 / ポストゲノム / 歯周病 / 歯周組織再生遺伝子 / 脂肪組織由来間葉系幹細胞 / 歯根膜遺伝子 / 遺伝子導入法 / 脂肪組織 / 未分化間葉系幹細胞 / アデノシンレセプター / ラフト / アデンシンレセプター / CD73 / CD26 / アデノシンデアミナーゼ / アデノシン Less

The effect of gradient FGF-2 on one-wall intrabony defect of periodontal tissue
- Principal Investigator
  
  SHIMABUKURO Yoshio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Osaka University
Development of novel minimal intervention methods for periodontal tissue regeneration therapy
- Principal Investigator
  
  YAMADA Satoru
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
脂肪組織由来の幹細胞とアディポカインによる炎症と再生の双方向性制御Principal Investigator
- Principal Investigator
  
  橋川智子
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
歯周組織幹細胞のエピジェネティクスとその制御の分子基盤
- Principal Investigator
  
  村上伸也
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
Molecular basis of predictable periodontal regeneration
- Principal Investigator
  
  MURAKAMI Shinya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
Regulation of S1P in pathogenesis of periodontal disease
- Principal Investigator
  
  YANAGITA Manabu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
Involvement of purine nucleotide in periodontal regeneration by transplantation of adipose tissue-derived stem cellsPrincipal Investigator
- Principal Investigator
  
  HASHIKAWA Tomoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
バイオインテリジェント化幹細胞を用いた歯周組織移植療法の開発
- Principal Investigator
  
  山田聡
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
The establishment of a new periodontal tissue regeneration therapyusing adipose-tissue derived stem cells
- Principal Investigator
  
  KITAMURA Masahiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
Development of customized periodontal tissue regenerative therapy by transtiptome analysis of periodontal ligament
- Principal Investigator
  
  MURAKAMI Shinya
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
Molecular basis of periodontal ligament stem cells by bioinformatics
- Principal Investigator
  
  YAMADA Satoru
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
炎症歯周組織における内因性アデノシンの抗炎症作用の解析Principal Investigator
- Principal Investigator
  
  橋川智子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
ラフトモデルに基づく歯周組織でのアデノシンレセプター活性化制御-新規Host modulating drugの開発を目指して-
- Principal Investigator
  
  MURAKAMI Shinya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
investigation of bFGF potential for egenerative therapy of dentin-pulp complex
- Principal Investigator
  
  SHIMABUKURO Yoshio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka University

All 2011 2009 2008 2007 2005 2004

All Journal Article Presentation Patent

[Journal Article] Fibroblast growth factor-2 stimulates directed migration of periodontal ligament cells via PI3/Akt signaling and CD44/hyaluronan interaction.2011
- Author(s)
  Shimabukuro Y, Hashikawa T, Yanagita M, Yamada S, Murakami S, et al.
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 226 Pages: 809-821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390530
[Journal Article] Fibroblast growth factor-2 stimulates directed migration of periodontal ligament cells via PI3-K/akt signaling and CD44/hyaluronan interaction2011
- Author(s)
  Shimabukuro Y, Terashima H, Takedachi M, Maeda K, Nakamura T, Sawada K, Kobashi M, Awata T, Oohara H, Kawahara T, Iwayama T, Hashikawa T, Yanagita M, Yamada S, Murakami S.
- Journal Title
  
  J.Cell.Physiol. 226
  
  Pages: 809-821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592427
[Journal Article] Fibroblast growth factor-2 stimulates directed migration of periodontal ligament cells via PI3/Akt signaling and CD44/hyaluronan interaction2011
- Author(s)
  Y Shimabukuro、T Hashikawa、M Yanagita、S Yamada、S Murakami
- Journal Title
  
  Journal of Cellular Physiology 226巻
  
  Pages: 809-821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390530
[Journal Article] Fibroblast growth factor-2 regulates the cell function of human dental pulp cells.2009
- Author(s)
  Shimabukuro Y, Ueda M, Ozasa M, Anzai J, Takedachi M, Yanagita M, Ito M, Hashikawa T, Yamada S, Murakami S.
- Journal Title
  
  J.Endodont. 35
  
  Pages: 1529-1535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592427
[Journal Article] Basic fibroblast growth factor regulates expression of heparan sulfate in human periodontal ligament cells2008
- Author(s)
  Y., Shimabukuro, T., Ichikawa, Y., Terashima, T., lwayama, H., Oohara, T., Kajikawa, R., Kobayashi, H., Terashima, M., Takedachi, M., Terakura, T., Hashikawa, S., Yamada, S., Murakami
- Journal Title
  
  Matrix Biol 27
  
  Pages: 232-241
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390560
[Journal Article] Fibroblast growth factor-2 regulates expression of osteopontin in periodontal ligament cells2008
- Author(s)
  Y., Terashima, Y., Shimabukuro, H., Terashima, M., Ozasa, M., Terakura, K., Ikezawa, T., Hashikawa, M., Takedachi, H., Oohara, S., Yamada, S., Murakami
- Journal Title
  
  J. Cell. Physiol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390560
[Journal Article] 歯周組織再生の現状と将来の展望2008
- Author(s)
  村上伸也・橋川智子
- Journal Title
  
  90
  
  Pages: 609-616
- Data Source
  KAKENHI-PROJECT-19592386
[Journal Article] 脂肪組織由来間葉系幹細胞を用いた歯周組織再生2007
- Author(s)
  橋川智子・村上伸也
- Journal Title
  
  日本歯科評論 778
  
  Pages: 39-40
- Data Source
  KAKENHI-PROJECT-19592386
[Journal Article] 脂肪組織由来間葉系幹細胞を用いた歯周組織再生2007
- Author(s)
  橋川智子
- Journal Title
  
  日本歯科評論 778
  
  Pages: 39-40
- Data Source
  KAKENHI-PROJECT-19592386
[Journal Article] 脂肪組織由来間葉系幹細胞を用いた歯周組織再生2007
- Author(s)
  橋川智子
- Journal Title
  
  日本歯科評論 778
  
  Pages: 39-40
- Data Source
  KAKENHI-PROJECT-18390559
[Journal Article] 脂肪組織由来間葉系幹細胞を用いた歯周組織再生2007
- Author(s)
  橋川智子、村上伸也
- Journal Title
  
  日本歯科評論 778
  
  Pages: 39-40
- Data Source
  KAKENHI-PROJECT-18390559
[Journal Article] 炎症歯周組織における内因性アデノシンの抗炎症作用の解析2005
- Author(s)
  橋川智子
- Journal Title
  
  炎症・再生 (印刷中)
- Data Source
  KAKENHI-PROJECT-16791311
[Journal Article] 炎症歯周組織における内因性アデノシンの抗炎症作用の解析2005
- Author(s)
  橋川智子
- Journal Title
  
  炎症・再生 (印刷中)
- Data Source
  KAKENHI-PROJECT-15659498
[Journal Article] Fibroblast growth factor-2 stimulates hyaluronan production by human dental pulp cells2005
- Author(s)
  Y.Shimabukuro, M.Ueda, T.Ichikawa, Y.Terashima, S.Yamada, Y.Kusumoto, M.Takedachi, M.Terakura, A.Kohyama, T.Hashikawa, S.Murakami
- Journal Title
  
  Journal of Endodontics (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370617
[Journal Article] 炎症歯周組織における内因性アデノシンの抗炎症作用の解析-歯肉線維芽細胞におけるアデノシンレセプター活性化の制御機構-2005
- Author(s)
  橋川智子
- Journal Title
  
  炎症・再生 25・3
  
  Pages: 181-185
- NAID
  10026499072
- Data Source
  KAKENHI-PROJECT-16791311
[Journal Article] Fibroblast growth factor-2 regulates the synthesis of hyaluronan by human periodontal ligament cells2005
- Author(s)
  Y.Shimabukuro, T.Ichikawa, S.Takayama, S.Yamada, M.Takedachi, M.Terakura, T.Hashikawa, S.Murakami
- Journal Title
  
  Journal of Cellular Physiology 203
  
  Pages: 557-563
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370617
[Journal Article] サイトカインと歯周病-炎症歯周組織における内因性アデノシンの抗炎症作用の解析-2004
- Author(s)
  橋川智子
- Journal Title
  
  炎症と免疫 12・4
  
  Pages: 463-469
- Data Source
  KAKENHI-PROJECT-15659498
[Journal Article] Regulation of adenosine receptor engagement by ecto-adenosine deaminase2004
- Author(s)
  Tomoko Hashikawa
- Journal Title
  
  The FASEB Journal 18
  
  Pages: 131-133
- Data Source
  KAKENHI-PROJECT-15659498
[Journal Article] サイトカインと歯周病 -炎症歯周組織における内因性アデノシンの抗炎症作用の解析-2004
- Author(s)
  橋川智子
- Journal Title
  
  炎症と免疫 12・4
  
  Pages: 463-469
- Data Source
  KAKENHI-PROJECT-16791311
[Patent] 歯周硬組織再生用組成物2007
- Inventor(s)
  村上伸也、橋川智子、澤芳樹、松山晃文、菰田弘
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Filing Date
  2007-09-20
- Overseas
- Data Source
  KAKENHI-PROJECT-18390559
[Patent] 歯周硬組織再生用組成物2007
- Inventor(s)
  村上伸也、橋川智子、澤芳樹、松山晃文、菰田弘
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Filing Date
  2007-09-20
- Overseas
- Data Source
  KAKENHI-PROJECT-19592386
[Patent] 歯周硬組織再生用組成物及び歯周硬組織を再生する方法(PCT第22条(1)に基づく指定国移行(PCT/JP2007/06287))2007
- Inventor(s)
  村上伸也、橋川智子、澤芳樹、松山晃文、菰田弘
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Industrial Property Number
  2006-259717
- Filing Date
  2007-09-20
- Overseas
- Data Source
  KAKENHI-PROJECT-19592386
[Patent] 歯周硬組織再生用組成物2007
- Inventor(s)
  村上伸也、橋川智子、澤芳樹、松由晃文、菰田弘
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Filing Date
  2007-09-20
- Overseas
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] Periodontal Regeneration by Transplantation of Adipose Tissue-derived Stem Cells2008
- Author(s)
  橋川智子
- Organizer
  IADR 86th General Session & Exhibition
- Place of Presentation
  Metro Toronto Convention Centre(カナダ)
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-19592386
[Presentation] 歯根膜特異的Periostinアイソフォームは歯根膜細胞の硬組織形成分化を促進する2008
- Author(s)
  田内拓司、山田聡、柳田学、橋川智子、村上伸也
- Organizer
  日本歯科保存学会2008年度秋季学術大会(第129回)
- Place of Presentation
  富山国際会議場(富山)
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-20390530
[Presentation] Periodontal Regeneration by Transplantation of Adipose Tissue-derived Stem Cells2008
- Author(s)
  T. HASHIKAWA
- Organizer
  IADR 86th General Session & Exhibition
- Place of Presentation
  Metro Toronto Convention Centre (カナダ)
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] 脂肪細胞由来未分化間葉系幹細胞の移植による歯周組織再生療法の開発2008
- Author(s)
  橋川智子
- Organizer
  第6回日本再生歯科学会学術大会・総会
- Place of Presentation
  日本歯科大学(東京)
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19592386
[Presentation] Analysis ofOsteogenic Differentiation of AdiposeTissue-derived Stem Cells2008
- Author(s)
  T. IWAYAMA, T. HASHIKAWA, M. MURAKAMI, 他8名
- Organizer
  ADR 86thGeneral Session & Exhibition
- Place of Presentation
  Metro Toronto Convention Centre(カナダ)
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] Periodontal Regeneration by Transplantation of Adipose Tissue-derived Stem Cells2008
- Author(s)
  橋川智子
- Organizer
  IADR 86th General Session & Exhibition
- Place of Presentation
  Metro Toronto Convention Centre (カナダ)
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-19592386
[Presentation] 歯根膜特異的Periostinアイソフォームは歯根膜細胞の硬組織形成分化を促進する2008
- Author(s)
  田内拓史、山田聡、橋川智子、北村正博、村上伸也, 他7名
- Organizer
  日本歯科保存学会2008年度秋季学術大会(第129回)
- Place of Presentation
  富山国際会議場(富山)
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] 脂肪組織由来未分化間葉系幹細胞の硬組織分化能の解析2008
- Author(s)
  岩山智明、橋川智子、村上伸也, 他5名
- Organizer
  第51回春季日本歯周病学会学術大会
- Place of Presentation
  大宮ソニックシティー(埼玉)
- Year and Date
  2008-04-26
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] Periodontal Regenerationby Transplantation of Adipose TissuederivedStem Cells2008
- Author(s)
  T. HASHIKAWA, M. MURAKAMI, 他6名
- Organizer
  IADR 86th GeneralSession & Exhibition
- Place of Presentation
  Metro Toronto Convention Centre(カナダ)
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] 脂肪細胞由来未分化間葉系幹細胞の移植による歯周組織再生療法の開発2008
- Author(s)
  橋川智子、村上伸也, 他4名
- Organizer
  第6回日本再生歯科学会学術大会・総会
- Place of Presentation
  日本歯科大学(東京)
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] 実験的歯周病モデルを用いた脂肪組織由来間葉系幹細胞の移植による歯周組織再生2008
- Author(s)
  小笹匡雄、橋川智子、村上伸也, 他5名
- Organizer
  第51回春季日本歯周病学会学術大会
- Place of Presentation
  大宮ソニックシティー(埼玉)
- Year and Date
  2008-04-26
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] 脂肪組織由来未分化間葉系幹細胞の移植による歯周組織再生療法の開発2008
- Author(s)
  小笹匡雄、橋川智子、村上伸也, 他5名
- Organizer
  日本歯科保存学会2008年度秋季学術大会(第129回)
- Place of Presentation
  富山国際会議場(富山)
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] 脂肪組織由来未分化間葉系幹細胞の硬組織形成細胞への分化誘導2007
- Author(s)
  橋川智子、村上伸也, 他4名
- Organizer
  第50回春季日本歯周病学会学術大会
- Place of Presentation
  横須賀芸術劇場(神奈川)
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] 脂肪組織由来未分化間葉系幹細胞の硬組織形成細胞への分化誘導2007
- Author(s)
  橋川智子
- Organizer
  日本歯周病学会
- Place of Presentation
  横須賀芸術劇場
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-18390559
[Presentation] 脂肪組織由来未分化間葉系幹細胞の硬組織形成細胞への分化誘導2007
- Author(s)
  橋川智子
- Organizer
  日本歯周病学会
- Place of Presentation
  横須賀芸術劇場
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-19592386

1. YAMADA Satoru (40359849)

# of Collaborated Projects: 10 results

# of Collaborated Products: 8 results
2. MURAKAMI Shinya (70239490)

# of Collaborated Projects: 9 results

# of Collaborated Products: 18 results
3. SHIMABUKURO Yoshio (50231361)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
4. YANAGITA Minabu (80379081)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
5. NOZAKI Takenori (30263304)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SAHO Teruyuki (10263295)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KITAMURA Masahiro (10243247)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. 池澤一彦 (80294114)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ABIKO Yoshimitsu (70050086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAJIKAWA Tetsuhiro (90611252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OZAKI Nobuhiro (80632132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HATTORI Masahira (70175537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HASHIKAWA Tomoko 橋川 智子

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脂肪組織由来の幹細胞とアディポカインによる炎症と再生の双方向性制御Principal Investigator

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Involvement of purine nucleotide in periodontal regeneration by transplantation of adipose tissue-derived stem cellsPrincipal Investigator

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炎症歯周組織における内因性アデノシンの抗炎症作用の解析Principal Investigator

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[Journal Article] Fibroblast growth factor-2 stimulates directed migration of periodontal ligament cells via PI3/Akt signaling and CD44/hyaluronan interaction.2011

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HASHIKAWA Tomoko 橋川智子