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Ihara Masafumi  猪原 匡史

… Alternative Names

IHARA Masafumi  猪原 匡史

猪原 匡史  イハラ マサフミ

Less
Researcher Number 00372590
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-7102-4048
Affiliation (Current) 2025: 国立研究開発法人国立循環器病研究センター, 病院, 部長
Affiliation (based on the past Project Information) *help 2016 – 2024: 国立研究開発法人国立循環器病研究センター, 病院, 部長
2016: 国立循環器病研究センター, 脳血管内科, 医長
2015: 国立研究開発法人国立循環器病研究センター, 病院, 医長
2013 – 2014: 独立行政法人国立循環器病研究センター, 病院, 医長
2012: 公益財団法人先端医療振興財団, 先端医療センター 再生医療研究部, 副部長 … More
2011: 京都大学, 医学研究科, 助教
2010 – 2011: 京都大学, 医学(系)研究科(研究院), 助教
2004: 京大, 医学(系)研究科(研究院) Less
Review Section/Research Field
Principal Investigator
Nerve anatomy/Neuropathology / Basic Section 59010:Rehabilitation science-related / Medium-sized Section 52:General internal medicine and related fields / Nerve anatomy/Neuropathology / Basic Section 51030:Pathophysiologic neuroscience-related / Medium-sized Section 57:Oral science and related fields / Pathobiological dentistry/Dental radiology / Neurology / Structural biochemistry
Except Principal Investigator
Basic Section 52010:General internal medicine-related … More / Basic Section 10030:Clinical psychology-related / Basic Section 56010:Neurosurgery-related / Basic Section 46020:Anatomy and histopathology of nervous system-related / Neurosurgery / Radiation science Less
Keywords
Principal Investigator
脳卒中 / 齲蝕原性細菌 / 口腔内細菌 / 摂食嚥下障害 / サルコペニア / 脳内出血 / 脳微小出血 / 脳出血 / ミュータンス菌 / 脳循環障害 … More / 脳神経疾患 / CADASIL / 血管性認知症 / シロスタゾール / アルツハイマー病 / 治療 / stroke / 歯科医科連携 / マトリソーム / 腸内細菌叢 / 摂食嚥下機能障害 / 高齢者 / 嚥下障害 / 分子標的 / Cnm / コラーゲン接着因子 / コラーゲン / 細菌 / 循環器・高血圧 / 歯学 / 歯科衛生 / アフリカ / コラーゲン結合性 / 連鎖球菌 / 脳内微小出血 / アミロイドβ / 抗糖化 / アミロイド / 抗糖化薬 / オリゴマー / 認知症 / 病理学 / 痴呆 / 脳・神経 / 神経科学 / 脳アミロイド血管症 / タウ / 抗糖化作用 / タキシフォリン / レスベラトロール / 脳循環予備能 / 一酸化窒素 / 両側総頸動脈狭窄術 / Sirt1 / 血液脳関門 / 内皮型一酸化窒素合成酵素 / 脳梗塞 / SIRT1 / サーチュイン / 長寿遺伝子 / Notch3 / iPS細胞 / Tg-SwDIマウス / モデルマウス / 微小梗塞 / 医師主導治験 / 臨床試験 / βアミロイド / アミロイド血管症 / ナノメディシン / ドラッグディリバリー / オートファジー / 脳虚血 … More
Except Principal Investigator
糖尿病 / TREM2 / 肥満 / 認知症 / タキシフォリン / 炎症 / ミクログリア / 脳血管障害 / RNF213 / 単球・ミクログリア / 治療戦略 / 早期予知バイオマーカー / 抑うつ / 人口知能 / Patient Health Record / 人工知能 / 心臓病 / 脳卒中 / PHR / コグニティブフレイル / 糖尿病性認知症 / 両側性交互刺激 / NIRS / CGM / 心不全 / 認知機能 / 血糖変動 / 単級・ミクログリア / 予防戦略 / アミロイドβ / イメグリミン / 脳内炎症 / 脳アミロイド血管症 / 血管合併症 / 単球 / 感受性遺伝子 / 頭蓋内血管狭窄 / 脳動脈狭窄 / 遺伝子解析 / 動脈硬化 / 頭蓋内動脈狭窄 / 多施設共同前向き観察研究 / 血管壁イメージング / もやもや病 / 遺伝子多型 / 脳梗塞 / 頭蓋内動脈狭窄症 / RNF213関連血管症 / RNF213遺伝子 / risk factors / gene polymorphism / intracranial stenosis / stroke / 単球機能 / 脳神経ネットワーク / 心理リハビリテーション / 脳内神経ネットワーク / 臨床 / 内科 / 脳神経疾患 / 研究者主導型試験 / 国際共同無作為化比較試験 / 降圧薬 / 血圧 / 配合剤 / アジア / 民族差 / 性差 / 研究者主導型臨床試験 / 降圧療法 / 高血圧 / 脳出血 / βアミロイド / 診断 / 金属錯体 / イメージング / 脳アミロイドアンギオパチー Less
  • Research Projects

    (27 results)
  • Research Products

    (238 results)
  • Co-Researchers

    (84 People)
  •  脳筋連関・TREM2に着目した糖尿病性認知症・コグニティブフレイルの予防戦略開発

    • Principal Investigator
      浅原 哲子 (佐藤哲子)
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Department of Clinical Research, National Hospital Organization Kyoto Medical Center
  •  Collaborative dental-medical research on the mechanism of intracerebral hemorrhage via cerebrovascular matrisome injury by oral bacteriaPrincipal Investigator

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      National Cardiovascular Center Research Institute
  •  A joint Japan-Korea-Taiwan 1000 CADASIL patient registry and international clinical trialPrincipal Investigator

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Fund for the Promotion of Joint International Research (International Collaborative Research)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Construction of an evaluation system for feeding and swallowing disorders and sarcopenia after stroke and search for key molecules in the brain-gut-muscle linkagePrincipal Investigator

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Prognostic role of white matter lesion topography in cerebrovascular disordersPrincipal Investigator

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  抑うつと前頭前野機能への両側性刺激の効果に関する基礎的fNIRS研究

    • Principal Investigator
      山内 美穂
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 10030:Clinical psychology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  糖尿病合併認知症の新規予防・治療戦略:TREM2を標的としたミクログリア形質改善

    • Principal Investigator
      田中 将志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Health Science University
  •  脳卒中・心臓病のCircular Healthcare Systemに関する研究

    • Principal Investigator
      飯原 弘二
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Development of novel evaluation system and prevention strategies for dementia associated with diabetes and obesity focusing on the fat-brain crosstalk and TREM2

    • Principal Investigator
      Satoh-Asahara Noriko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Department of Clinical Research, National Hospital Organization Kyoto Medical Center
  •  脳血管障害・肥満の共通基盤候補としてのRNF213遺伝子多型と機能的意義の解明

    • Principal Investigator
      野口 倫生
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Elucidating the Mechanisms of Cardiovascular Disease Development in IGT Using New Generation CGM in a 3000-Person Cohort

    • Principal Investigator
      Hosoda Kiminori
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Dysphagia severity and decision making algorithm after acute stoke in the elderlyPrincipal Investigator

    • Principal Investigator
      Ihara Masafumi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  RNF213-related vasculopathy and stroke: mechanisms and treatment strategies

    • Principal Investigator
      Okazaki Shuhei
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46020:Anatomy and histopathology of nervous system-related
    • Research Institution
      National Hospital Organization Osaka National Hospital Institute for Clinical Reserch
      Osaka University
  •  Pathological Significance of TREM2 in Obesity/Diabetes-Related Cognitive Impairment through the Brain-Adipose Tissue Axis

    • Principal Investigator
      TANAKA Masashi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Health Science University
  •  A study to elucidate the mechanism of intracerebral heorrhage induced by collagen-binding Streptococcus mutans and to develop a novel preventive therapyPrincipal Investigator

    • Principal Investigator
      Ihara Masafumi
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Fundamental research on the effect of auditory bilateral stimulation on depressive symptoms

    • Principal Investigator
      Yamauchi Miho
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 10030:Clinical psychology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Development of predictive indicators and treatment strategies for dementia associated with diabetes and obesity focusing TREM2 and monocyte function

    • Principal Investigator
      Satoh-Asahara Noriko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Department of Clinical Research, National Hospital Organization Kyoto Medical Center
  •  Triple therapy prevention of Recurrent Intracerebral Disease EveNts Trial

    • Principal Investigator
      Toyoda Kazunori
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurosurgery
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Establishment of international liaison between medical doctors and dentists for the purpose of reduction of stroke in Nigeria and KenyaPrincipal Investigator

    • Principal Investigator
      Ihara Masafumi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Study to understand mechanism of hemorrhagic stroke induced by oral bacteriaPrincipal Investigator

    • Principal Investigator
      IHARA MASAFUMI
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Development of anti-glycosylation agents for Alzheimer diseasePrincipal Investigator

    • Principal Investigator
      IHARA MASAFUMI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Development of nuclear medical imaging probes targeting cerebral amyloid antipathy

    • Principal Investigator
      Ono Masahiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Kyoto University
  •  A study to elucidate the mechanism by which the longevity gene product SIRT1 confers neuroprotectionPrincipal Investigator

    • Principal Investigator
      IHARA Masafumi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Regenerative therapy for Alzheimer's disease and cerebral amyloid angiopathyPrincipal Investigator

    • Principal Investigator
      IHARA Masafumi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      National Cardiovascular Center Research Institute
      Foundation for Biomedical Research and Innovation
      Kyoto University
  •  Exploration of treatment of hereditary vascular dementia CADASIL using patient-derived iPS cells and its model micePrincipal Investigator

    • Principal Investigator
      IHARA Masafumi
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University
  •  融合ナノプローブ薬剤送達システムを用いた脳虚血巣選択的オートファジー制御への挑戦Principal Investigator

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Kyoto University
  •  セプチン/脂質によるαシヌクレインポリマー/フィラメント形成機序に関する検討Principal Investigator

    • Principal Investigator
      猪原 匡史
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent

  • [Book] Annual Review神経20192019

    • Author(s)
      殿村 修一,猪原 匡史
    • Total Pages
      326
    • Publisher
      中外学社
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Book] モデル動物利用マニュアル.疾患モデルの作製と利用一循環器疾患2010

    • Author(s)
      北徹, 堀内久徳, 柳田素子, 猪原匡史, 冨本秀和, 並河徹編
    • Total Pages
      486
    • Publisher
      (株)エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Book] 慢性脳低灌流モデル.北徹, 堀内久徳, 柳田素子, 猪原匡史, 冨本秀和, 並河徹編「モデル動物利用マニュアル. 疾患モデルの作製と利用-循環器疾患」(株)

    • Author(s)
      猪原匡史, 冨本秀和
    • Total Pages
      486
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] High pillow and spontaneous vertebral artery dissection: A case-control study implicating “Shogun pillow syndrome”2024

    • Author(s)
      Egashira Shuhei、Tanaka Tomotaka、Yamashiro Takayuki、Saito Satoshi、Abe Soichiro、Yoshimoto Takeshi、Fukuma Kazuki、Ishiyama Hiroyuki、Yamaguchi Eriko、Hattori Yorito、Ogata Soshiro、Nishimura Kunihiro、Koga Masatoshi、Toyoda Kazunori、Debette St?phanie、Ihara Masafumi
    • Journal Title

      European Stroke Journal

      Volume: 0 Issue: 2 Pages: 0-0

    • DOI

      10.1177/23969873231226029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15721, KAKENHI-PROJECT-23K27953
  • [Journal Article] Pro‐Hemorrhagic Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Associated with <i>NOTCH3</i> p.<scp>R75P</scp> Mutation with Low Vascular NOTCH3 Aggregation Property2024

    • Author(s)
      Ishiyama Hiroyuki、Kim Hyunjin、Ihara Masafumi et al.
    • Journal Title

      Annals of Neurology

      Volume: Mar 23 Online ahead of print. Issue: 6 Pages: 00-00

    • DOI

      10.1002/ana.26916

    • Data Source
      KAKENHI-PROJECT-23K27953
  • [Journal Article] Long-Term Resveratrol Intake for Cognitive and Cerebral Blood Flow Impairment in Carotid Artery Stenosis/Occlusion2024

    • Author(s)
      Hattori Yorito、Kakino Yoshinori、Hattori Yuji、Iwashita Mari、Uchiyama Hitoshi、Noda Kotaro、Yoshimoto Takeshi、Iida Hidehiro、Ihara Masafumi
    • Journal Title

      Journal of Stroke

      Volume: 26 Issue: 1 Pages: 64-74

    • DOI

      10.5853/jos.2023.02733

    • Data Source
      KAKENHI-PROJECT-23K27953
  • [Journal Article] Pupillometer-Based Neurological Pupil Index Differential: A Potential Predictor of Post-Stroke Delirium2024

    • Author(s)
      Kotaro Noda, Tomotaka Tanaka, Soichiro Abe, Ryo Usui, Misa Matsumoto, Yoshito Arakaki, Hiroyuki Kida, Ryoma Inui, Kaoru Kohama, Kazuo Washida, Sonu M. M. Bhaskar, Masatoshi Koga, Kazunori Toyoda, Masafumi Ihara
    • Journal Title

      Journal of Stroke

      Volume: in press

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23KF0126
  • [Journal Article] Pre-existing sarcopenia and swallowing outcomes in acute stroke patients2023

    • Author(s)
      Fukuma Kazuki、Kamada Masatoshi、Yamamoto Kazuya、Yokota Chiaki、Abe Soichiro、Nakazawa Shinsaku、Tanaka Tomotaka、Chichikawa Takuro、Nakaoku Yuriko、Nishimura Kunihiro、Koga Masatoshi、Takaya Shigetoshi、Sugimoto Ken、Nishioka Shinta、Wakabayashi Hidetaka、Fujishima Ichiro、Ihara Masafumi
    • Journal Title

      Clinical Nutrition

      Volume: 42 Issue: 8 Pages: 1454-1461

    • DOI

      10.1016/j.clnu.2023.06.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15721, KAKENHI-PROJECT-19K11312, KAKENHI-PROJECT-20K11250, KAKENHI-PROJECT-21K11332, KAKENHI-PROJECT-23K27953
  • [Journal Article] Tmax Mismatch Ratio to Identify Intracranial Atherosclerotic Stenosis‐Related Large‐Vessel Occlusion Before Endovascular Therapy2023

    • Author(s)
      Yoshimoto Takeshi、Inoue Manabu、Tanaka Kanta、Koge Junpei、Shiozawa Masayuki、Kamogawa Naruhiko、Ishiyama Hiroyuki、Abe Soichiro、Imamura Hirotoshi、Kataoka Hiroharu、Koga Masatoshi、Ihara Masafumi、Toyoda Kazunori
    • Journal Title

      Journal of the American Heart Association

      Volume: 12 Issue: 14

    • DOI

      10.1161/jaha.123.029899

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14790, KAKENHI-PROJECT-23K27953
  • [Journal Article] Efficacy and safety of cilostazol in mild cognitive impairment: a randomized clinical trial2023

    • Author(s)
      Saito S, Oishi N, et al (他35名、25番目)
    • Journal Title

      JAMA Network Open

      Volume: 6 Issue: 12 Pages: e2344938-e2344938

    • DOI

      10.1001/jamanetworkopen.2023.44938

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07593, KAKENHI-PROJECT-21K16944, KAKENHI-PROJECT-19H00597, KAKENHI-PROJECT-23K27953
  • [Journal Article] RNF213 p.R4810K Variant Increases the Risk of Vasospastic Angina2023

    • Author(s)
      Ishiyama H, Tanaka T, Yoshimoto T, Ihara M et al.
    • Journal Title

      JACC: Asia

      Volume: 3 Issue: 5 Pages: 821-823

    • DOI

      10.1016/j.jacasi.2023.05.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07359, KAKENHI-PROJECT-23K24602
  • [Journal Article] Association of thyroid peroxidase antibody with the RNF213 p.R4810K variant in ischemic stroke/transient ischemic attack2023

    • Author(s)
      Yoshimoto Takeshi、Ishiyama Hiroyuki、Ihara Masafumi et al.
    • Journal Title

      Atherosclerosis

      Volume: 382 Pages: 117281-117281

    • DOI

      10.1016/j.atherosclerosis.2023.117281

    • Data Source
      KAKENHI-PROJECT-23K27953
  • [Journal Article] Novel Therapeutic Potentials of Taxifolin for Obesity-Induced Hepatic Steatosis, Fibrogenesis, and Tumorigenesis2023

    • Author(s)
      Inoue Takayuki、Fu Bin、Nishio Miwako、Tanaka Miyako、Kato Hisashi、Tanaka Masashi、Itoh Michiko、Yamakage Hajime、Ochi Kozue、Ito Ayaka、Shiraki Yukihiro、Saito Satoshi、Ihara Masafumi、Nishimura Hideo、Kawamoto Atsuhiko、Inoue Shian、Saeki Kumiko、Enomoto Atsushi、Suganami Takayoshi、Satoh-Asahara Noriko
    • Journal Title

      Nutrients

      Volume: 15 Issue: 2 Pages: 350-350

    • DOI

      10.3390/nu15020350

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08526, KAKENHI-PROJECT-21K08571, KAKENHI-PROJECT-22K07456, KAKENHI-PROJECT-22K08667, KAKENHI-PROJECT-22K11700, KAKENHI-PROJECT-22K11720, KAKENHI-PROJECT-22K19524, KAKENHI-PROJECT-22K19723, KAKENHI-PROJECT-21K17557, KAKENHI-PROJECT-19KK0249, KAKENHI-PUBLICLY-21H05625, KAKENHI-PROJECT-20H03447, KAKENHI-PROJECT-21H02835, KAKENHI-PROJECT-19K07905, KAKENHI-PROJECT-19K07927, KAKENHI-PUBLICLY-22H04806
  • [Journal Article] Plasma mid‐regional pro‐adrenomedullin: A biomarker of the ischemic penumbra in hyperacute stroke2023

    • Author(s)
      Ishiyama Hiroyuki、Tanaka Tomotaka、Saito Satoshi、Koyama Teruhide、Kitamura Akihiro、Inoue Manabu、Fukushima Naoya、Morita Yoshiaki、Koga Masatoshi、Toyoda Kazunori、Kuriyama Nagato、Urushitani Makoto、Ihara Masafumi
    • Journal Title

      Brain Pathology

      Volume: 33 Issue: 2

    • DOI

      10.1111/bpa.13110

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K16944, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-20H04047
  • [Journal Article] Taxifolin Suppresses Inflammatory Responses of High-Glucose-Stimulated Mouse Microglia by Attenuating the TXNIP?NLRP3 Axis2023

    • Author(s)
      Iwasa Masayo、Kato Hisashi、Iwashita Kaori、Yamakage Hajime、Kato Sayaka、Saito Satoshi、Ihara Masafumi、Nishimura Hideo、Kawamoto Atsuhiko、Suganami Takayoshi、Tanaka Masashi、Satoh-Asahara Noriko
    • Journal Title

      Nutrients

      Volume: 15 Issue: 12 Pages: 2738-2738

    • DOI

      10.3390/nu15122738

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19524, KAKENHI-PROJECT-22K19723, KAKENHI-PROJECT-21K17557, KAKENHI-PROJECT-22K07456, KAKENHI-PROJECT-22K11720, KAKENHI-PROJECT-22K07411, KAKENHI-PUBLICLY-22H04806, KAKENHI-PROJECT-21H02835
  • [Journal Article] Complement 3 Is a Potential Biomarker for Cerebral Amyloid Angiopathy2022

    • Author(s)
      Saito Satoshi、Yamashiro Takayuki、Yamauchi Miho、Yamamoto Yumi、Noguchi Michio、Tomita Tsutomu、Kawakami Daisuke、Shikata Masamitsu、Tanaka Tomotaka、Ihara Masafumi
    • Journal Title

      Journal of Alzheimer's Disease

      Volume: 89 Issue: 1 Pages: 381-387

    • DOI

      10.3233/jad-220494

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K16944, KAKENHI-PROJECT-20H04047
  • [Journal Article] Impact of blood flow volume in determining the destination of intracardiac thrombi using computational fluid dynamics2022

    • Author(s)
      Hattori Yorito、Tagawa Naoki、Nakamura Masanori、Ihara Masafumi
    • Journal Title

      eNeurologicalSci

      Volume: 29 Pages: 100437-100437

    • DOI

      10.1016/j.ensci.2022.100437

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H04047
  • [Journal Article] <i>RNF213</i> p.R4810K Variant Carriers with Intracranial Arterial Stenosis Have a Low Atherosclerotic Burden2022

    • Author(s)
      Ohara Mariko、Yoshimoto Takeshi、Okazaki Shuhei、Gon Yasufumi、Todo Kenichi、Sasaki Tsutomu、Takasugi Junji、Ohara Nobuyuki、Ihara Masafumi、Mochizuki Hideki
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 29 Issue: 11 Pages: 1655-1662

    • DOI

      10.5551/jat.63379

    • NAID

      130008134294

    • ISSN
      1340-3478, 1880-3873
    • Year and Date
      2022-11-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06922
  • [Journal Article] Effect of the RNF213 p.R4810K Variant on the Progression of Intracranial Artery Stenosis2022

    • Author(s)
      Okazaki Shuhei、Yoshimoto Takeshi、Ohara Mariko、Takagaki Masatoshi、Nakamura Hajime、Watanabe Kotaro、Gon Yasufumi、Todo Kenichi、Sasaki Tsutomu、Araki Hiroyuki、Yamada Tomomi、Manabe Shirou、Kishima Haruhiko、Ihara Masafumi、Mochizuki Hideki
    • Journal Title

      Neurology Genetics

      Volume: 8 Issue: 5

    • DOI

      10.1212/nxg.0000000000200029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06922
  • [Journal Article] Developing an Asymmetry Method for Detecting Postictal Hyperperfusion in Poststroke Epilepsy2022

    • Author(s)
      Kazuki Fukuma, Tomotaka Tanaka, Shigetoshi Takaya, Maya Tojima, Katsuya Kobayashi, Akihiro Shimotake, Yoshiaki Morita, Kunihiro Nishimura, Masatoshi Koga, Kazunori Toyoda, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda, Masafumi Ihara
    • Journal Title

      Frontiers of neurology

      Volume: eCollection Pages: 877386-877386

    • DOI

      10.3389/fneur.2022.877386

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-22K15729, KAKENHI-PROJECT-19K16888, KAKENHI-PROJECT-19H03574, KAKENHI-PROJECT-22K15721, KAKENHI-PROJECT-20H04047
  • [Journal Article] Risk Assessment of Cnm-Positive Streptococcus mutans in Stroke Survivors (RAMESSES): Protocol for a Multicenter Prospective Cohort Study2022

    • Author(s)
      Hosoki Satoshi、Hattori Yorito、Saito Satoshi、Takegami Misa、Tonomura Shuichi、Yamamoto Yumi、Ikeda Shuhei、Hosomi Naohisa、Oishi Naoya、Morita Yoshiaki、Miyamoto Yoshihiro、Nomura Ryota、Nakano Kazuhiko、Ihara Masafumi
    • Journal Title

      Frontiers in Neurology

      Volume: 13 Pages: 816147-816147

    • DOI

      10.3389/fneur.2022.816147

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K16944, KAKENHI-PROJECT-20H04047
  • [Journal Article] Endothelial BACE1: Bridging the Gap Between Hypertension and Alzheimer’s Disease2022

    • Author(s)
      Ihara Masafumi
    • Journal Title

      Circulation Research

      Volume: 130 Issue: 9 Pages: 1342-1344

    • DOI

      10.1161/circresaha.122.321078

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H04047
  • [Journal Article] Association of Cortical Superficial Siderosis with Post-Stroke Epilepsy2022

    • Author(s)
      Tomotaka Tanaka, Kazuki Fukuma, Soichiro Abe, Soichiro Matsubara, Shuhei Ikeda, Naruhiko Kamogawa, Hiroyuki Ishiyama, Satoshi Hosoki, Katsuya Kobayashi, Akihiro Shimiotake, Yuriko Nakaoku, Soshiro Ogata, Kunihiro Nishimura, Masatoshi Koga, Kazunori Toyoda, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda, Masafumi Ihara
    • Journal Title

      Annals of Neurology

      Volume: Online ahead of print Issue: 2 Pages: 357-370

    • DOI

      10.1002/ana.26497

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-22K15729, KAKENHI-PROJECT-19K16888, KAKENHI-PROJECT-19H03574, KAKENHI-PROJECT-22K15721, KAKENHI-PROJECT-20H04047
  • [Journal Article] Clinical and imaging features of nonmotor onset seizure in poststroke epilepsy2022

    • Author(s)
      Kazuki Fukuma, Shunhei Ikeda, Tomotaka Tanaka, Naruhiko Kamogawa, Hiroyuki Ishiyama, Soichiro Abe, Maya Tojima, Katsuya Kobayashi, Akihiro Shimotake, Yuriko Nakaoku, Kunihiro Nishimura, Masatoshi Koga, Kazunori Toyoda, Riki Matsumoto, Akio Ikeda, Masafumi Ihara
    • Journal Title

      Epilepsia

      Volume: 63 Issue: 8 Pages: 2068-2080

    • DOI

      10.1111/epi.17308

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-22K15729, KAKENHI-PROJECT-19K16888, KAKENHI-PROJECT-19H03574, KAKENHI-PROJECT-22K15721, KAKENHI-PROJECT-20H04047
  • [Journal Article] Taxifolin: A Potential Therapeutic Agent for Cerebral Amyloid Angiopathy2021

    • Author(s)
      Saito Satoshi、Tanaka Masashi、Satoh-Asahara Noriko、Carare Roxana Octavia、Ihara Masafumi
    • Journal Title

      Frontiers in Pharmacology

      Volume: 12 Pages: 643357-643357

    • DOI

      10.3389/fphar.2021.643357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07927, KAKENHI-PROJECT-18H02737, KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-21H02835
  • [Journal Article] A Nationwide Multi-Center Questionnaire Survey on the Real-World State and Issues Regarding Post-Stroke Complications in Japan.2021

    • Author(s)
      Ikeda S, Washida K, Tanaka T, Kitajima E, Chiba T, Fukuma K, Yoshimoto T, Saito S, Hattori Y, Ihara M.
    • Journal Title

      J Stroke Cerebrovasc Dis.

      Volume: 30(4) Issue: 4 Pages: 105656-105656

    • DOI

      10.1016/j.jstrokecerebrovasdis.2021.105656

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16888, KAKENHI-PROJECT-20H04047
  • [Journal Article] Phase angle from bioelectrical impedance analysis is a useful indicator of muscle quality2021

    • Author(s)
      Akamatsu Yasunori、Kusakabe Toru、Arai Hiroshi、Yamamoto Yuji、Nakao Kazuwa、Ikeue Kentaro、Ishihara Yuki、Tagami Tetsuya、Yasoda Akihiro、Ishii Kojiro、Satoh‐Asahara Noriko
    • Journal Title

      Journal of Cachexia, Sarcopenia and Muscle

      Volume: 13 Issue: 1 Pages: 180-189

    • DOI

      10.1002/jcsm.12860

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-21H02835, KAKENHI-PROJECT-18K11093, KAKENHI-PROJECT-21K11691, KAKENHI-PROJECT-20K19561
  • [Journal Article] RNF213 p.R4810K (c.14429G &gt; A) Variant Determines Anatomical Variations of the Circle of Willis in Cerebrovascular Disease2021

    • Author(s)
      Eto Futoshi、Yoshimoto Takeshi、Okazaki Shuhei、Nishimura Kunihiro、Ogura Shiori、Yamaguchi Eriko、Fukuma Kazuki、Saito Satoshi、Washida Kazuo、Koga Masatoshi、Toyoda Kazunori、Morimoto Takaaki、Maruyama Hirofumi、Koizumi Akio、Ihara Masafumi
    • Journal Title

      Frontiers in Aging Neuroscience

      Volume: 13 Pages: 681743-681743

    • DOI

      10.3389/fnagi.2021.681743

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19K06922
  • [Journal Article] Late Neurological Deterioration after Acute Intracerebral Hemorrhage: A post hoc Analysis of the ATACH-2 Trial2020

    • Author(s)
      Okazaki Shuhei、Yamamoto Haruko、Foster Lydia、Fukuda-Doi Mayumi、Koga Masatoshi、Ihara Masafumi、Toyoda Kazunori、Palesch Yuko?Y.、Qureshi Adnan?I.
    • Journal Title

      Cerebrovascular Diseases

      Volume: 49 Issue: 1 Pages: 26-31

    • DOI

      10.1159/000506117

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04308, KAKENHI-PROJECT-17H04670
  • [Journal Article] Microbiota in cerebrovascular disease: A key player and future therapeutic target2020

    • Author(s)
      Tonomura Shuichi、Ihara Masafumi、Friedland Robert P
    • Journal Title

      Journal of Cerebral Blood Flow & Metabolism

      Volume: n.d. Issue: 7 Pages: 1368-1380

    • DOI

      10.1177/0271678x20918031

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22610, KAKENHI-PROJECT-20J15262
  • [Journal Article] D-dimer level and outcome of minor ischemic stroke with large vessel occlusion2020

    • Author(s)
      Sato Takeo、Sato Shoichiro、Yamagami Hiroshi、Komatsu Teppei、Mizoguchi Tadataka、Yoshimoto Takeshi、Takagi Masahito、Ihara Masafumi、Koga Masatoshi、Iwata Hiroyoshi、Matsushima Masato、Toyoda Kazunori、Iguchi Yasuyuki
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 413 Pages: 116814-116814

    • DOI

      10.1016/j.jns.2020.116814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Oral carriage of Streptococcus mutans harboring the cnm gene is related to an increased incidence of cerebral microbleeds2020

    • Author(s)
      Hosoki S, Saito S, Tonomura S, Ishiyama H, Yoshimoto T, Ikeda S, Ikenouchi H, Yamamoto Y, Hattori Y, Miwa K, Friedland RP, Carare RO, Nakahara J, Suzuki N, Koga M, Toyoda K, Nomura R, Nakano K, Takegami M, Ihara M.
    • Journal Title

      Stroke

      Volume: 51 Issue: 12 Pages: 3632-3639

    • DOI

      10.1161/strokeaha.120.029607

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03010, KAKENHI-PROJECT-19J00106, KAKENHI-PROJECT-19K22610, KAKENHI-PROJECT-20J15262
  • [Journal Article] 齲歯・歯周病と脳卒中・認知症の関連(RAMESSES研究)2020

    • Author(s)
      猪原匡史,齊藤聡,服部頼都,細木聡,山本由美,殿村修一
    • Journal Title

      神経治療学

      Volume: n.d.

    • NAID

      130007981249

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22610
  • [Journal Article] Statin treatment can reduce incidence of early seizure in acute ischemic stroke: A propensity score analysis2020

    • Author(s)
      Matsubara Soichiro、Tanaka Tomotaka、Tomari Shinya、Fukuma Kazuki、Ishiyama Hiroyuki、Abe Soichiro、Arimizu Takuro、Yamaguchi Yoshitaka、Ogata Soshiro、Nishimura Kunihiro、Koga Masatoshi、Ando Yukio、Toyoda Kazunori、Ihara Masafumi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1968-1968

    • DOI

      10.1038/s41598-020-58652-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-19K16888
  • [Journal Article] Visualizing prolonged hyperperfusion in post-stroke epilepsy using postictal subtraction SPECT2020

    • Author(s)
      Kazuki Fukuma, Katsufumi Kajimoto, Tomotaka Tanaka, Shigetoshi Takaya, Katsuya Kobayashi, Akihiro Shimotake, Riki Matsumoto, Akio Ikeda, Kazunori Toyoda, Masfumi Ihara
    • Journal Title

      Journal of Cerebral Blood Flow and Metabolism

      Volume: - Issue: 1 Pages: 146-156

    • DOI

      10.1177/0271678x20902742

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-16K09715, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-19K16888, KAKENHI-PROJECT-19H03574, KAKENHI-PROJECT-20K21573
  • [Journal Article] Human iPS cell-derived mural cells as an in vitro model of hereditary cerebral small vessel disease2020

    • Author(s)
      Yamamoto Yumi、Kojima Katsutoshi、Taura Daisuke、Sone Masakatsu、Washida Kazuo、Egawa Naohiro、Kondo Takayuki、Minakawa Eiko N.、Tsukita Kayoko、Enami Takako、Tomimoto Hidekazu、Mizuno Toshiki、Kalaria Raj N.、Inagaki Nobuya、Takahashi Ryosuke、Harada-Shiba Mariko、Ihara Masafumi、Inoue Haruhisa
    • Journal Title

      Molecular Brain

      Volume: 13 Issue: 1 Pages: 38-38

    • DOI

      10.1186/s13041-020-00573-w

    • NAID

      120006818682

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08514, KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-17K09880, KAKENHI-PROJECT-18K15347, KAKENHI-PROJECT-20K07883, KAKENHI-PROJECT-18K07058, KAKENHI-PROJECT-19J40007
  • [Journal Article] アフリカでの脳卒中低減を目指した医科―歯科国際連携の試み.2020

    • Author(s)
      殿村 修一,井上 学,角田 良介,野村 良太,仲野 和彦,猪原 匡史
    • Journal Title

      脳卒中

      Volume: 42 Pages: 107-108

    • NAID

      130007815617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Potential Therapeutic Approaches for Cerebral Amyloid Angiopathy and Alzheimer’s Disease2020

    • Author(s)
      Tanaka Masashi、Saito Satoshi、Inoue Takayuki、Satoh-Asahara Noriko、Ihara Masafumi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 6 Pages: 1992-1992

    • DOI

      10.3390/ijms21061992

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07927, KAKENHI-PROJECT-19K11760, KAKENHI-PROJECT-19J00106, KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-18H02737
  • [Journal Article] Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia2020

    • Author(s)
      Uemura Maiko T.、Maki Takakuni、Ihara Masafumi、Lee Virginia M. Y.、Trojanowski John Q.
    • Journal Title

      Frontiers in Aging Neuroscience

      Volume: 12 Pages: 80-80

    • DOI

      10.3389/fnagi.2020.00080

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22610, KAKENHI-PROJECT-17H04670
  • [Journal Article] Concentrations of dabigatran administered after acute ischemic stroke2020

    • Author(s)
      Wada Shinichi、Inoue Manabu、Matsuki Takayuki、Okata Takuya、Kumamoto Masaya、Tagawa Naoki、Yoshimura Sohei、Okamoto Akira、Miyata Toshiyuki、Ihara Masafumi、Toyoda Kazunori、Koga Masatoshi
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 411 Pages: 116704-116704

    • DOI

      10.1016/j.jns.2020.116704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Large aortic arch plaques correlate with CHADS2 and CHA2DS2-VASc scores in cryptogenic stroke2019

    • Author(s)
      Ueno Yuji、Tateishi Yohei、Doijiri Ryosuke、Kuriki Ayako、Shimizu Takahiro、Kikuno Muneaki、Shimada Yoshiaki、Takekawa Hidehiro、Yamaguchi Eriko、Koga Masatoshi、Kamiya Yuki、Ihara Masafumi、Tsujino Akira、Hirata Koichi、Toyoda Kazunori、Hasegawa Yasuhiro、Hattori Nobutaka、Urabe Takao
    • Journal Title

      Atherosclerosis

      Volume: 284 Pages: 181-186

    • DOI

      10.1016/j.atherosclerosis.2019.03.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] The rise and rise of cerebral small vessel disease: implications for vascular cognitive impairment and dementia2019

    • Author(s)
      Kalaria Raj N、Hase Yoshiki、Ihara Masafumi
    • Journal Title

      Future Neurology

      Volume: 14 Issue: 2

    • DOI

      10.2217/fnl-2019-0004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Association of <i>CYP2C19</i> Polymorphisms With Clopidogrel Reactivity and Clinical Outcomes in Chronic Ischemic Stroke2019

    • Author(s)
      Tanaka Tomotaka、Yamagami Hiroshi、Ihara Masafumi、et al.
    • Journal Title

      Circ J

      Volume: 83 Issue: 6 Pages: 1385-1393

    • DOI

      10.1253/circj.CJ-18-1386

    • NAID

      130007652780

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2019-05-24
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Stroke, cerebrovascular diseases and vascular cognitive impairment in Africa2019

    • Author(s)
      Akinyemi Rufus O.、Owolabi Mayowa O.、Ihara Masafumi、Damasceno Albertino、Ogunniyi Adesola、Dotchin Catherine、Paddick Stella-Maria、Ogeng’o Julius、Walker Richard、Kalaria Raj N.
    • Journal Title

      Brain Research Bulletin

      Volume: 145 Pages: 97-108

    • DOI

      10.1016/j.brainresbull.2018.05.018

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Clinical and Radiological Characteristics of Intracranial Artery Dissection Using Recently Proposed Diagnostic Criteria2019

    • Author(s)
      Nakamura Y, Yamaguchi Y, Makita N, Morita Y, Ide T, Wada S, Mizoguchi T, Ikenouchi H, Miwa K, Yi K, Irie K, Shimohama S, Ihara M, Toyoda K, Koga M
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: Epub Issue: 6 Pages: 30063-1

    • DOI

      10.1016/j.jstrokecerebrovasdis.2019.02.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09485, KAKENHI-PROJECT-16H05279, KAKENHI-PROJECT-17H04670
  • [Journal Article] Balloon-like Mobile Plaque in the Innominate Artery: Ultrasonographic and Pathological Perspectives of Repetitive Embolism2019

    • Author(s)
      Ikenouchi Hajime、Washida Kazuo、Yoshimoto Takeshi、Fukuma Kazuki、Saito Satoshi、Inoue Yosuke、Matsuda Hitoshi、Ihara Masafumi
    • Journal Title

      Journal of Stroke and Cerebrovascular Diseases

      Volume: 28 Issue: 7 Pages: e95-e97

    • DOI

      10.1016/j.jstrokecerebrovasdis.2019.04.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-19J00106
  • [Journal Article] Novel Therapeutic Potentials of Taxifolin for Amyloid-β-associated Neurodegenerative Diseases and Other Diseases: Recent Advances and Future Perspectives2019

    • Author(s)
      Tanaka Masashi、Saito Satoshi、Inoue Takayuki、Satoh-Asahara Noriko、Ihara Masafumi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 9 Pages: 2139-2139

    • DOI

      10.3390/ijms20092139

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07927, KAKENHI-PROJECT-19K11760, KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-18H02737, KAKENHI-PROJECT-19J00106
  • [Journal Article] Use of Diffusion‐Weighted Imaging‐Alberta Stroke Program Early Computed Tomography Score (DWI‐ASPECTS) and Ischemic Core Volume to Determine the Malignant Profile in Acute Stroke2019

    • Author(s)
      Yoshimoto Takeshi、Inoue Manabu、Yamagami Hiroshi、Fujita Kyohei、Tanaka Kanta、Ando Daisuke、Sonoda Kazutaka、Kamogawa Naruhiko、Koga Masatoshi、Ihara Masafumi、Toyoda Kazunori
    • Journal Title

      Journal of the American Heart Association

      Volume: 8 Issue: 22

    • DOI

      10.1161/jaha.119.012558

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-17K00426
  • [Journal Article] Pleiotropic neuroprotective effects of taxifolin in cerebral amyloid angiopathy2019

    • Author(s)
      Inoue Takayuki、Saito Satoshi、Tanaka Masashi、Yamakage Hajime、Kusakabe Toru、Shimatsu Akira、Ihara Masafumi、Satoh-Asahara Noriko
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 116 Issue: 20 Pages: 10031-10038

    • DOI

      10.1073/pnas.1901659116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07905, KAKENHI-PROJECT-19K07927, KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-18H02737, KAKENHI-PROJECT-19J00106
  • [Journal Article] Detrimental Effect of Chronic Hypertension on Leptomeningeal Collateral Flow in Acute Ischemic Stroke2019

    • Author(s)
      Fujita Kyohei、Tanaka Kanta、Yamagami Hiroshi、Ide Toshihiro、Ishiyama Hiroyuki、Sonoda Kazutaka、Satow Tetsu、Takahashi Jun C.、Ihara Masafumi、Koga Masatoshi、Yokota Takanori、Toyoda Kazunori
    • Journal Title

      Stroke

      Volume: 50 Issue: 7 Pages: 1751-1757

    • DOI

      10.1161/strokeaha.119.025142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Effect of fingolimod on oligodendrocyte maturation under prolonged cerebral hypoperfusion2019

    • Author(s)
      Yasuda Ken、Maki Takakuni、Saito Satoshi、Yamamoto Yumi、Kinoshita Hisanori、Choi Yoon Kyung、Arumugam Thiruma Valavan、Lim Yun-An、Chen Christopher Li Hsian、Wong Peter Tsun-Hon、Ihara Masafumi、Takahashi Ryosuke
    • Journal Title

      Brain Research

      Volume: 1720 Pages: 146294-146294

    • DOI

      10.1016/j.brainres.2019.06.013

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-19J00106
  • [Journal Article] Detection of Stenosis Progression in Intracranial Vertebral Artery Dissection Using Carotid Ultrasonography2019

    • Author(s)
      Wada Shinichi、Koga Masatoshi、Makita Naoki、Nakamura Yuki、Miwa Kaori、Ide Toshihiro、Yi Kenichiro、Mizoguchi Tadataka、Yamaguchi Yoshitaka、Ihara Masafumi、Toyoda Kazunori
    • Journal Title

      Journal of Stroke and Cerebrovascular Diseases

      Volume: 28 Issue: 8 Pages: 2201-2206

    • DOI

      10.1016/j.jstrokecerebrovasdis.2019.04.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-16K09485
  • [Journal Article] アフリカでの脳卒中低減を目指した医科―歯科国際連携の試み2019

    • Author(s)
      1.殿村 修一,井上 学,角田 良介,野村 良太,仲野 和彦,猪原 匡史
    • Journal Title

      脳卒中

      Volume: 印刷中

    • NAID

      130007815617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Prevalence of RNF213 p.R4810K Variant in Early-Onset Stroke With Intracranial Arterial Stenosis2019

    • Author(s)
      Kamimura Teppei、Okazaki Shuhei、Morimoto Takaaki、Kobayashi Hatasu、Harada Kouji、Tomita Tsutomu、Higashiyama Aya、Yoshimoto Takeshi、Takahashi Jun C.、Nakagawara Jyoji、Koga Masatoshi、Toyoda Kazunori、Maruyama Hirofumi、Koizumi Akio、Ihara Masafumi
    • Journal Title

      Stroke

      Volume: 50 Issue: 6 Pages: 1561-1563

    • DOI

      10.1161/strokeaha.118.024712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06922, KAKENHI-PROJECT-19K10608, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-17H04670
  • [Journal Article] Significance of Nonfocal Symptoms in Patients With Transient Ischemic Attack2018

    • Author(s)
      Ishihara Toshiya、Sato Shoichiro、Uehara Toshiyuki、..., Toyoda Kazunori、Minematsu Kazuo
    • Journal Title

      Stroke

      Volume: 49 Issue: 8 Pages: 1893-1898

    • DOI

      10.1161/strokeaha.118.022009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04308
  • [Journal Article] Collagen-binding Streptococcus mutans tied to cerebral microbleeds and intracerebral hemorrhage2018

    • Author(s)
      Ihara Masafumi、Tonomura Shuichi、Yamamoto Yumi、Saito Satoshi
    • Journal Title

      Future Neurology

      Volume: 13 Issue: 4 Pages: 219-224

    • DOI

      10.2217/fnl-2018-0016

    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Seasonal Variations in Neurological Severity and Outcomes of Ischemic Stroke ― 5-Year Single-Center Observational Study ―2018

    • Author(s)
      Toyoda Kazunori、Koga Masatoshi、Yamagami Hiroshi、Yokota Chiaki、Sato Shoichiro、Inoue Manabu、Tanaka Tomotaka、Endo Kaoru、Fujinami Jun、Ihara Masafumi、Nagatsuka Kazuyuki、Minematsu Kazuo
    • Journal Title

      Circ J

      Volume: 82 Issue: 5 Pages: 1443-1450

    • DOI

      10.1253/circj.CJ-17-1310

    • NAID

      130006725986

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04308
  • [Journal Article] Anti-Xa Activity and Event Risk in Patients With Direct Factor Xa Inhibitors Initiated Early After Stroke2018

    • Author(s)
      Wada Shinichi、Toyoda Kazunori、Sato Shoichiro、Matsuki Takayuki、Okata Takuya、Kumamoto Masaya、Tagawa Naoki、Inoue Manabu、Okamoto Akira、Ihara Masafumi、Kitazono Takanari、Miyata Toshiyuki、Koga Masatoshi
    • Journal Title

      Circ J

      Volume: 82 Issue: 11 Pages: 2872-2879

    • DOI

      10.1253/circj.CJ-18-0506

    • NAID

      40021697278

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2018-10-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04308, KAKENHI-PROJECT-16K09834
  • [Journal Article] Dysregulation of RNF213 promotes cerebral hypoperfusion2018

    • Author(s)
      Morimoto T, Enmi J, Hattori Y, Iguchi S, Saito S, Harada K, Okuda H, Mineharu Y, Takagi Y, Youssefian S, Iida H, Miyamoto S, Ihara M, Kobayashi H, Koizumi A.
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 3607-3607

    • DOI

      10.1038/s41598-018-22064-8

    • NAID

      120006510289

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-15K19243, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-15K19963
  • [Journal Article] Outcome Prediction in Acute Stroke Patients by Continuous Glucose Monitoring2018

    • Author(s)
      Wada Shinichi、Yoshimura Sohei、Inoue Manabu、Matsuki Takayuki、Arihiro Shoji、Koga Masatoshi、Kitazono Takanari、Makino Hisashi、Hosoda Kiminori、Ihara Masafumi、Toyoda Kazunori
    • Journal Title

      Journal of the American Heart Association

      Volume: 7 Issue: 8

    • DOI

      10.1161/jaha.118.008744

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04308
  • [Journal Article] Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia2017

    • Author(s)
      Duncombe Jessica、Kitamura Akihiro、Hase Yoshiki、Ihara Masafumi、Kalaria Raj?N.、Horsburgh Karen
    • Journal Title

      Clinical Science

      Volume: 131 Issue: 19 Pages: 2451-2468

    • DOI

      10.1042/cs20160727

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Journal Article] Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy2017

    • Author(s)
      Satoshi Saito, Yumi Yamamoto, Takakuni Maki, Yorito Hattori, Hideki Ito, Katsuhiko Mizuno, Mariko Harada-Shiba, Raj N. Kalaria, Masanori Fukushima, Ryosuke Takahashi, Masafumi Ihara
    • Journal Title

      Acta Neuropathologica Communications

      Volume: 5 Issue: 1 Pages: 26-26

    • DOI

      10.1186/s40478-017-0429-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14958, KAKENHI-PROJECT-15H04271
  • [Journal Article] Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion2017

    • Author(s)
      Kitamura Akihiro、Manso Yasmina、Duncombe Jessica、Searcy James、Koudelka Juraj、Binnie Margaret、Webster Scott、Lennen Ross、Jansen Maurits、Marshall Ian、Ihara Masafumi、Kalaria Raj N.、Horsburgh Karen
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 4299-4299

    • DOI

      10.1038/s41598-017-04082-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Swallowing-induced displacement of the carotid artery as a risk of stroke: Flip-flop phenomenon2017

    • Author(s)
      Kinoshita Naoto、Saito Kozue、Tanaka Tomotaka、Kajimoto Katsufumi、Yamagami Hiroshi、Morita Yoshiaki、Ihara Masafumi、Nagatsuka Kazuyuki
    • Journal Title

      Neurology

      Volume: 89 Issue: 15 Pages: 1643-1644

    • DOI

      10.1212/wnl.0000000000004492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Medial temporal lobe atrophy is the norm in cerebrovascular dementias2017

    • Author(s)
      Kalaria R. N.、Ihara M.
    • Journal Title

      European Journal of Neurology

      Volume: 24 Issue: 4 Pages: 539-540

    • DOI

      10.1111/ene.13243

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Journal Article] Frontal White Matter Hyperintensities, Clasmatodendrosis and Gliovascular Abnormalities in Ageing and Post-stroke Dementia2016

    • Author(s)
      13.Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung’u MN, Foster V, Craggs LJL, Washida K, Okamoto Y, Thomas AJ, Polvikosk TM, Allan JM, Oakley AE, O’Brien JT, Horsburgh K, Ihara M, Kalaria RN
    • Journal Title

      Brain

      Volume: 139 Issue: 1 Pages: 242-258

    • DOI

      10.1093/brain/awv328

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Hemisphere asymmetry of response to treatment in an Alzheimer’s disease mouse model2016

    • Author(s)
      Manousopoulou A, Saito S, Yamamoto Y, Al-Daghri NM, Ihara M, Carare RO, Garbis SD
    • Journal Title

      J Alzheimers Dis

      Volume: 21 Issue: 2 Pages: 333-338

    • DOI

      10.3233/jad-151078

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
  • [Journal Article] Imaging of Cerebral Amyloid Angiopathy with Bivalent 99mTc-Hydroxamamide Complexes2016

    • Author(s)
      Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Hiroyuki Kimura, Hatsue Ishibashi-Ueda, Yoko Okamoto, Masafumi Ihara, Hideo Saji.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 25990-25990

    • DOI

      10.1038/srep25990

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16J05493, KAKENHI-PROJECT-26293274
  • [Journal Article] Interaction between cerebrovascular disease and Alzheimer pathology2016

    • Author(s)
      Saito S, Ihara M
    • Journal Title

      Curr Opin Psychiatry

      Volume: 29 Issue: 2 Pages: 168-173

    • DOI

      10.1097/yco.0000000000000239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
  • [Journal Article] Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory2016

    • Author(s)
      Kitamura A, Saito S, Maki A, Ayaki T, Oishi N, Kalaria RN, Hattori Y, Yamamoto Y, Urushitani M, Horsburgh K, Fukuyama H, Takahashi R, Ihara M
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: - Issue: 9 Pages: 1592-1602

    • DOI

      10.1177/0271678x15606717

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26290023, KAKENHI-PROJECT-15K09920
  • [Journal Article] Novel Bivalent 99mTc-Complex with N-Methyl-Substituted Hydroxamamide as Probe for Imaging of Cerebral Amyloid Angiopathy2016

    • Author(s)
      Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Masashi Yoshimura, Hatsue Ishibashi-Ueda, Masafumi Ihara, Hideo Saji.
    • Journal Title

      PLoS One

      Volume: 11(9) Issue: 9 Pages: e0163969-e0163969

    • DOI

      10.1371/journal.pone.0163969

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16J05493, KAKENHI-PROJECT-26293274
  • [Journal Article] う蝕原因菌と脳出血の関連-脳口連関-.2016

    • Author(s)
      殿村修一,仲野和彦,猪原匡史
    • Journal Title

      日本歯科論評

      Volume: 76 Pages: 14-15

    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Journal Article] Gradual Carotid Artery Stenosis in Mice Closely Replicates Hypoperfusive Vascular Dementia in Humans.2016

    • Author(s)
      Hattori Y, Enmi J, Iguchi S, Saito S, Yamamoto Y, Tsuji M, Nagatsuka K, Kalaria RN, Iida H, Ihara M
    • Journal Title

      Journal of the American Heart Association

      Volume: 5 Issue: 2

    • DOI

      10.1161/jaha.115.002757

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461867, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26640034
  • [Journal Article] Emerging evidence for pathogenesis of sporadic cerebral small vessel disease2016

    • Author(s)
      Ihara M, Yamamoto Y
    • Journal Title

      Stroke

      Volume: 47 Issue: 2 Pages: 554-560

    • DOI

      10.1161/strokeaha.115.009627

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-16K18387
  • [Journal Article] Influence of low-dose aspirin on cerebral amyloid angiopathy in mice2016

    • Author(s)
      Hattori Y, Maki T, Saito S, Yamamoto Y, Nagatsuka K, Ihara M
    • Journal Title

      J Alzheimers Dis

      Volume: - Issue: 3 Pages: 1037-1045

    • DOI

      10.3233/jad-160013

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Oral Cnm-positive Streptococcus Mutans Expressing Collagen Binding Activity is a Risk Factor for Cerebral Microbleeds and Cognitive Impairment.2016

    • Author(s)
      Watanabe I, Kuriyama N, Miyatani F, Nomura R, Naka S, Nakano K, Ihara M, Iwai K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Tamura A, Mizuno T, Akazawa K6, Takada A, Takeda K, Yamada K, Nakagawa M, Tanaka T, Kanamura N, Friedland RP, Watanabe Y.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 1-5

    • DOI

      10.1038/srep38561

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10318, KAKENHI-PROJECT-16K14573, KAKENHI-PROJECT-16H06277
  • [Journal Article] Stroke Injury, cognitive Impairment and vascular dementia2016

    • Author(s)
      Kalaria RN, Akinyemi R, Ihara M
    • Journal Title

      Biochim Biophys Acta

      Volume: - Issue: 5 Pages: 915-925

    • DOI

      10.1016/j.bbadis.2016.01.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] Structure-Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents that Selectively Detect Neurofibrillary Tangles in Alzheimer’s Disease Brains2015

    • Author(s)
      Matsumura K, Ono M, Kitada A, Watanabe H, Yoshimura M, Iikuni S, Kimura H, Okamoto Y, Ihara M, Saji H.
    • Journal Title

      J Med Chem

      Volume: 58 Issue: 18 Pages: 7241-7257

    • DOI

      10.1021/acs.jmedchem.5b00440

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01555, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-14J05961
  • [Journal Article] Immunolocalisation of PDGFRβ and pericytes in CADASIL2015

    • Author(s)
      Craggs LJL, Fenwick R, Oakley AE, Ihara M, Kalaria RN
    • Journal Title

      Neuropath Appl Neurobiol

      Volume: 41 Issue: 4 Pages: 557-570

    • DOI

      10.1111/nan.12188

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] SIRT1 attenuates severe ischemic damage by preserving cerebral blood flow.2015

    • Author(s)
      Hattori Y, Okamoto Y, Nagatsuka K, Takahashi R, Kalaria RN, Kinoshita M, Ihara M
    • Journal Title

      NeuroReport

      Volume: 26 Issue: 3 Pages: 113-117

    • DOI

      10.1097/wnr.0000000000000308

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26640034, KAKENHI-PLANNED-23111002
  • [Journal Article] Mild cognitive impairment: at the crossroad of neurodegeneration and vascular dysfunction2015

    • Author(s)
      Saito S, Yamamoto Y, Ihara M
    • Journal Title

      Curr Alzheimer Res

      Volume: 12 Issue: 6 Pages: 507-512

    • DOI

      10.2174/1567205012666150530202508

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
  • [Journal Article] A novel mouse model of subcortical infarcts with dementia.2015

    • Author(s)
      Hattori Y, Enmi J, Kitamura A, Yamamoto Y, Saito S, Takahashi Y, Iguchi S, Tsuji M, Yamahara K, Nagatsuka K, Iida H, Ihara M
    • Journal Title

      The Journal of Neuroscience

      Volume: 35 Issue: 9 Pages: 3915-3928

    • DOI

      10.1523/jneurosci.3970-14.2015

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461867, KAKENHI-PROJECT-25640031
  • [Journal Article] microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.2015

    • Author(s)
      Kim J, Yoon H, Horie T, Burchett JM, Restivo JL, Rotllan N, Ram&#237;rez CM, Verghese PB, Ihara M, Hoe HS, Esau C, Fern&#225;ndez-Hernando C, Holtzman DM, Cirrito JR, Ono K, Kim J.
    • Journal Title

      J Neurosci.

      Volume: 35(44) Issue: 44 Pages: 14717-26

    • DOI

      10.1523/jneurosci.2053-15.2015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26293186
  • [Journal Article] Translation of pre-clinical studies into successful clinical trials for Alzheimer’s disease: what are the roadblocks and how can they be overcome?2015

    • Author(s)
      Banik A, Brown RE, Bamburg J, Lahiri DK, Khurana D, Friedland RP, Chen W, Ding Y, Mudher A, Padjen AL, Mukaetova-Ladinska E, Ihara M, Srivastava E, Srivastava MVP, Masters CL, Kalaria RN, Anand A
    • Journal Title

      J Alzheimer Dis

      Volume: 47 Issue: 4 Pages: 815-843

    • DOI

      10.3233/jad-150136

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Journal Article] 注目される脳小血管病による認知症.2014

    • Author(s)
      猪原匡史
    • Journal Title

      Dementia Japan

      Volume: 28 Pages: 57-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid.2014

    • Author(s)
      Maki T, Okamoto Y, Carare RO, Hase Y, Hattori Y, Hawkes CA, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda H, Taguchi A, Takahashi R, Miyakawa T, Kalaria RN, Lo EH, Arai K, Ihara M
    • Journal Title

      Ann Clin Transl Neurol

      Volume: 1 Issue: 8 Pages: 519-533

    • DOI

      10.1002/acn3.79

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] Cilostazol add-on therapy in patients with mild dementia receiving donepezil : a retrospective study2014

    • Author(s)
      Ihara M, Nishino M, Taguchi A, Yamamoto Y, Hattori Y, Saito S, Takahashi Y, Tsuji M, Kasahara Y, Takata Y, Okada M
    • Journal Title

      PloS ONE

      Volume: 9(2) Issue: 2 Pages: e89516-e89516

    • DOI

      10.1371/journal.pone.0089516

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] 注目される脳小血管病による認知症.2014

    • Author(s)
      猪原匡史
    • Journal Title

      Dementia Japan

      Volume: 28 Pages: 57-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] Effects of intravenous administration of umbilical cord blood CD34+ cells in a mouse model of neonatal stroke.2014

    • Author(s)
      Tsuji M, Taguchi A, Ohshima M, Kasahara Y, Sato Y, Tsuda H, Otani K, Yamahara K, Ihara M, Harada-Shiba M, Ikeda T, Matsuyama T.
    • Journal Title

      Neuroscience

      Volume: 263 Pages: 148-158

    • DOI

      10.1016/j.neuroscience.2014.01.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23500448, KAKENHI-PROJECT-23791220, KAKENHI-PROJECT-24591617, KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26461630
  • [Journal Article] Silent Information Regulator 2 Homolog 1 Counters Cerebral Hypoperfusion Injury by Deacetylating Endothelial Nitric Oxide Synthase2014

    • Author(s)
      Hattori Y, Okamoto Y, Maki T, Yamamoto Y, Oishi N, Yamahara K, Nagatsuka K, Takahashi R, Kalaria RN, Fukuyama H, Kinoshita M, Ihara M
    • Journal Title

      Stroke

      Volume: 45 Issue: 11 Pages: 3403-3411

    • DOI

      10.1161/strokeaha.114.006265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390292, KAKENHI-PROJECT-24791296, KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26640034, KAKENHI-PROJECT-22220003
  • [Journal Article] 注目される脳小血管病による認知症2014

    • Author(s)
      猪原匡史
    • Journal Title

      Dementia Japan

      Volume: 28(1) Pages: 57-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] 高血糖とアルツハイマー病.2014

    • Author(s)
      猪原匡史
    • Journal Title

      医学のあゆみ

      Volume: 249 Pages: 545-550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] A mouse model of chronic cerebral hypoperfusion characterizing features of cognitive impairment2014

    • Author(s)
      Ihara M, Taguchi A, Maki T, Washida K, Tomimoto H
    • Journal Title

      Methods Mol Biol

      Volume: 1135 Pages: 95-102

    • DOI

      10.1007/978-1-4939-0320-7_8

    • ISBN
      9781493903191, 9781493903207
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Motor and cognitive impairment in a mouse model of ischemic carotid artery disease.2014

    • Author(s)
      Hattori Y, Kitamura A, Tsuji M, Nagatsuka K, Ihara M
    • Journal Title

      Neurosci Lett

      Volume: 581 Pages: 1-6

    • DOI

      10.1016/j.neulet.2014.08.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] 高血糖とアルツハイマー病.2014

    • Author(s)
      猪原匡史
    • Journal Title

      医学のあゆみ

      Volume: 249 Pages: 545-550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] Greater suitability of the Montreal Cognitive Assessment against the Mini-Mental State Examination in the detection of vascular cognitive impairment2013

    • Author(s)
      Ihara M, Okamoto Y, Takahashi R
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 22(6) Issue: 6 Pages: 737-41

    • DOI

      10.1016/j.jstrokecerebrovasdis.2012.01.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182, KAKENHI-PROJECT-25640031
  • [Journal Article] An highly reproducible model of cerebralischemia/reperfusion with extended survival in CB-17 mice2013

    • Author(s)
      Kasahara Y, Ihara M, Nakagomi T, Momota Y, Sterm D, Matsuyama T, Taguchi A
    • Journal Title

      Neurosci Res

      Volume: 76 Issue: 3 Pages: 163-168

    • DOI

      10.1016/j.neures.2013.04.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592271, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23500448, KAKENHI-PROJECT-25463159, KAKENHI-PROJECT-25640031
  • [Journal Article] Structure-activity Relationships and in vivo Evaluation of Quinoxaline Derivatives for PET Imaging of β-Amyloid Plaques.2013

    • Author(s)
      Yoshimura M, Ono M, Matsumura K, Watanabe H, Kimura H, Cui M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H.
    • Journal Title

      ACS Med Chem Lett

      Volume: 4 Issue: 7 Pages: 596-600

    • DOI

      10.1021/ml4000707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Vascular and neurodegenerative pathways-will they meet?2013

    • Author(s)
      Kalaria RN, Ihara M
    • Journal Title

      Nat Rev Neurol

      Volume: 9(9) Issue: 9 Pages: 487-488

    • DOI

      10.1038/nrneurol.2013.164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Synthesis and biological evaluation of novel styryl benzimidazole derivatives as probes for imaging of neurofibrillary tangles in Alzheimer's disease.2013

    • Author(s)
      Matsumura K, Ono M, Yoshimura M, Kimura H, Watanabe H, Okamoto Y, Ihara M, Takahashi R, Saji H.
    • Journal Title

      Bioorg Med Chem

      Volume: 21 Issue: 11 Pages: 3356-3362

    • DOI

      10.1016/j.bmc.2013.02.054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-24659564, KAKENHI-PROJECT-25640031
  • [Journal Article] 認知症の診断と治療を目指した小血管病の管理2013

    • Author(s)
      猪原匡史
    • Journal Title

      Brain and Nerve

      Volume: 65(7) Pages: 801-809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] 認知症の診断と治療を目指した小血管病の管理2013

    • Author(s)
      猪原匡史
    • Journal Title

      Brain and Nerve

      Volume: 65 Pages: 801-809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] Visualization of Lenticulostriate Arteries by Flow-Sensitive Black-Blood MR Angiography on a 1.5T MRI System: A Comparative Study between Subjects with and without Stroke. AJNR Am J Neuroradiol.2013

    • Author(s)
      Okuchi S
    • Journal Title

      AJNR Am J Neuroradiol

      Volume: 34 Issue: 4 Pages: 780-784

    • DOI

      10.3174/ajnr.a3310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-24591757, KAKENHI-PROJECT-25640031, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002
  • [Journal Article] Association of Physical Activity with the Visuospatial/Executive Functions of the Montreal Cognitive Assessment in Patients with Vascular Cognitive Impairment2013

    • Author(s)
      Ihara M, Okamoto Y, Hase Y, Takahashi R
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 22(7) Issue: 7 Pages: 339-4

    • DOI

      10.1016/j.jstrokecerebrovasdis.2012.10.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Experimental and clinical challenge for neuroregeneration following stroke.2013

    • Author(s)
      Kasahara Y, Ihara M, Taguchi A.
    • Journal Title

      Front Neurol Neurosci

      Volume: 32 Pages: 69-75

    • DOI

      10.1159/000346416

    • ISBN
      9783318023084, 9783318023091
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] White matter pathology and disconnection in the frontal lobe in CADASIL2013

    • Author(s)
      Craggs LJL, Yamamoto Y, et al.
    • Journal Title

      Neuropathol Appl Neurobiol

      Volume: (Epub ahead of orint) Issue: 5 Pages: 591-602

    • DOI

      10.1111/nan.12073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07954, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] 認知症における血管病の重要性2013

    • Author(s)
      猪原匡史
    • Journal Title

      脳循環代謝

      Volume: 24(2) Pages: 83-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] 認知症における血管病の重要性.2013

    • Author(s)
      猪原匡史
    • Journal Title

      脳循環代謝

      Volume: 24 Pages: 83-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] Cilostazol improves cognitive function in patients with mild cognitive impairment : A retrospective analysis2013

    • Author(s)
      Taguchi A, Takata Y, Ihara M, Kasahara Y, Tsuji M, Nishino M, Stern D, Okada M
    • Journal Title

      Psychogeriatrics

      Volume: 13(3) Issue: 3 Pages: 164-169

    • DOI

      10.1111/psyg.12021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] Vascular Risk Factors and Neurodegeneration in Ageing related Dementias : Alzheimer' s Disease and Vascular Dementia2013

    • Author(s)
      Akinyemi R, Mukaetova-Ladinska E, Attems J, Ihara M, Kalaria RN
    • Journal Title

      Curr Alzheimer Res

      Volume: 10(6) Issue: 6 Pages: 642-53

    • DOI

      10.2174/15672050113109990037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] 認知症における血管病の重要性.2013

    • Author(s)
      猪原匡史
    • Journal Title

      脳循環代謝

      Volume: 24 Pages: 83-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Journal Article] Development of Novel (123)I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer's Disease.2013

    • Author(s)
      Ono M, Cheng Y, Kimura H, Watanabe H, Matsumura K, Yoshimura M, Iikuni S, Okamoto Y, Ihara M, Takahashi R, Saji H.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 9 Pages: e74104-e74104

    • DOI

      10.1371/journal.pone.0074104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
  • [Journal Article] 18F-labeled Phenyldiazenyl Benzothiazole for invivo Imaging of Neurofibrillary Tangles in Alzheimer's Disease Brains2012

    • Author(s)
      Matsumura K, Ono M, Kimura H, Ueda M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H
    • Journal Title

      ACS Med Chem Lett

      Volume: 3(1) Issue: 1 Pages: 58-62

    • DOI

      10.1021/ml200230e

    • Data Source
      KAKENHI-PROJECT-23650182
  • [Journal Article] Environmental enrichment ameliorated high fat diet-induced Aβdeposition and memory deficit in APP transgenic mice2012

    • Author(s)
      Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Asada M, Watanabe K, Hayashida N, Ihara M, Ito H, ShimohamaS, Kihara T, Kinoshita A
    • Journal Title

      Neurobiology of Aging

      Volume: 33 Issue: 5 Pages: 11-23

    • DOI

      10.1016/j.neurobiolaging.2011.10.028

    • NAID

      120003988394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23591243, KAKENHI-PROJECT-23650182, KAKENHI-PUBLICLY-24111524
  • [Journal Article] Cerebral hypoperfusion induces microinfarcts in cerebral amyloid angiopathy2012

    • Author(s)
      Okamoto Y, Yamamoto T, Kalaria RN, Senzaki H, Maki T, Hase Y, Kitamura A, Washida K, Yamada M, Ito H, Tomimoto H, Takahashi R, Ihara M
    • Journal Title

      Acta Neuropathol

      Volume: 123(3) Issue: 3 Pages: 381-394

    • DOI

      10.1007/s00401-011-0925-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Cilostazol, a phosphodiesterase inhibitor, prevents no-reflow and hemorrhage in mice with focal cerebral ischemia2012

    • Author(s)
      Hase Y, Okamoto Y, Fujita Y, KitamuraA, Ito H, Maki T, Washida K, TakahashiR, Ihara M
    • Journal Title

      Experimental Neurology

      Volume: 233 Issue: 1 Pages: 523-533

    • DOI

      10.1016/j.expneurol.2011.11.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Selective white matter abnormalities in a novel rat model of vascular dementia2012

    • Author(s)
      Kitamura A, Fujita Y, Oishi N, KalariaR N, Washida K, Maki T, Okamoto Y, HaseY, Yamada M, Takahashi J, Ito H, Tomimoto H, Fukuyama H, Takahashi R, Ihara M
    • Journal Title

      Neurobiology of Aging

      Volume: 33 Issue: 5 Pages: 25-35

    • DOI

      10.1016/j.neurobiolaging.2011.10.033

    • NAID

      120003988349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22220003, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Phenyldiazenyl benzothiazole derivatives as probes for in vivo imaging of neurofibrillary tangles in Alzheimer's disease brains2011

    • Author(s)
      Matsumura K, Ono M, et al
    • Journal Title

      Med Chem Comm

      Volume: 2 Issue: 7 Pages: 596-600

    • DOI

      10.1039/c1md00034a

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Selective white matter pathology induces a specific impainnent in spatial working memory2011

    • Author(s)
      Coltman R, Spain A, et al
    • Journal Title

      Neurobiol Aging

      Volume: 32 Issue: 12 Pages: 2324.e7-2324.e12

    • DOI

      10.1016/j.neurobiolaging.2010.09.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Angiogenic roles of adreno medullin through VEGF induction2011

    • Author(s)
      Maki T, Ihara M, Fujita Y, Nambu T, Harada H, Ito H, Nakao K, Tomimoto H, Takahashi R
    • Journal Title

      Neuroreport

      Volume: 22 Issue: 9 Pages: 442-447

    • DOI

      10.1097/wnr.0b013e32834757e4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice.2011

    • Author(s)
      Maki T, Ihara M, et al.
    • Journal Title

      Stroke

      Volume: 42 Pages: 1125-1131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Watershed Infarcts in a multiple microembolic model of monkey2011

    • Author(s)
      Maki T, Wakita H, Mase M, Itagaki I, Saito N, Ono F, Adachi K, Ito H, Takahashi R, Ihara M, Tomimoto H
    • Journal Title

      Neuroscience Letters

      Volume: 499 Issue: 2 Pages: 80-83

    • DOI

      10.1016/j.neulet.2011.05.036

    • NAID

      120003238944

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-21591106, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011

    • Author(s)
      Tomimoto H
    • Journal Title

      Stroke

      Volume: 42(4) Issue: 4 Pages: 1122-8

    • DOI

      10.1161/strokeaha.110.603399

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005, KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains2011

    • Author(s)
      Ono M, Hayashi S, et al
    • Journal Title

      ACS Chem Neurosci

      Volume: 2 Issue: 5 Pages: 269-275

    • DOI

      10.1021/cn200002t

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] The influence of chronic cerebral hypoperfusion on cognitive function and amyloid b metabolism in APP overexpressing mice2011

    • Author(s)
      Yamada M, Ihara M, Okamoto Y, Maki T, Washida K, Kitamura A, Hase Y, Ito H, Takao K, Miyakawa T, Kalaria RN, Tomimoto H, Takahashi R
    • Journal Title

      PLoS One

      Volume: 6 Issue: 1 Pages: e16567-e16567

    • DOI

      10.1371/journal.pone.0016567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233
  • [Journal Article] Co localization of 14-3-3 proteins with SOD1 in Lewy Body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model2011

    • Author(s)
      Okamoto Y, Shirakashi Y, Ihara M, Urushitani M, Oono M, Kawamoto Y, Yamashita H, Shimohama S, Kato S, Hirano A, Tomimoto H, Ito H, Takahashi R
    • Journal Title

      PLoS One

      Volume: 6 Issue: 5 Pages: e20427-e20427

    • DOI

      10.1371/journal.pone.0020427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930, KAKENHI-PROJECT-22659171, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation2011

    • Author(s)
      Ito H, Nakamura M, Komure O, Ayaki T, Wate R, Maruyama H, Nakamura Y, FujitaK, Kaneko S, Okamoto Y, Ihara M, Konishi T, Ogasawara K, Hirano A, Kusaka H, KajiR, Takahashi R, Kawakami H
    • Journal Title

      Acta Neuropathologica

      Volume: 122 Issue: 2 Pages: 223-229

    • DOI

      10.1007/s00401-011-0842-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23591246, KAKENHI-PROJECT-23650182
  • [Journal Article] Lessons from a mouse model characterizing features of vascular cognitive impairment with white matter changes2011

    • Author(s)
      Ihara M, Tomimoto H
    • Journal Title

      J Aging Res

      Volume: 2011 Pages: 978761-978761

    • DOI

      10.4061/2011/978761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] The influence of chronic cerebral hypoperfusion on cognitive function and amyloid β metabolism in APP overexpressing mice.2011

    • Author(s)
      Yamada M, Ihara M, et.al.
    • Journal Title

      PLoS One

      Volume: 6

    • NAID

      120002871155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] An autopsy case of SOD1-related ALS with TDP-43 positive inclusions2011

    • Author(s)
      Okamoto Y, Ihara M, Urushitani M, Yamashita H, Kondo T, Tanigaki A, Oono M, Kawamata J, Ikemoto A, Kawamoto Y, Takahashi R, Ito H
    • Journal Title

      Neurology

      Volume: 77:1993-1995 Issue: 22 Pages: 1993-1995

    • DOI

      10.1212/wnl.0b013e31823a0cfc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590930, KAKENHI-PROJECT-22659171, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] A mouse model characterizing features of vascular dementia with hippocampal atrophy.2010

    • Author(s)
      Nishio K, Ihara M, et al.
    • Journal Title

      Stroke

      Volume: 41 Pages: 1278-1284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies.2010

    • Author(s)
      Ihara M, Plvikoski TM, et al.
    • Journal Title

      Acta Neuropathol

      Volume: 119 Pages: 579-589

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] 亜急性に進行する発動性低下のみを呈した内包膝部branch atheromatous diseaseの一例2010

    • Author(s)
      北村彰浩, 猪原匡史, ら
    • Journal Title

      脳卒中

      Volume: 32 Pages: 384-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] 脳血管障害による認知機能障害;Vascular cognitive impairment2010

    • Author(s)
      猪原匡史
    • Journal Title

      老年精神医学雑誌

      Volume: 22 Pages: 53-59

    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] 脳血管障害に基づく認知機能障害の病態2010

    • Author(s)
      猪原匡史, 岡本洋子, ら
    • Journal Title

      脳卒中

      Volume: 32 Pages: 614-620

    • NAID

      10027895761

    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Early protective effect of bone marrow mononuclear cells against ischemic white matter damage through augmentation of cerebral blood flow.2010

    • Author(s)
      Fujita Y, Ihara M, et al.
    • Journal Title

      Stroke

      Volume: 41 Pages: 2938-2943

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to PPAR-γ activation in mice with chronic cerebral hypoperfusion.2010

    • Author(s)
      Washida K, Ihara M, et al.
    • Journal Title

      Stroke

      Volume: 41 Pages: 1798-1806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Journal Article] Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β -amyloid

    • Author(s)
      Maki T, Okamoto Y, Carare R, Hase Y, Hattori Y, Hawkes C, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda, H, Taguchi A, Takahashi R, Miyakawa T, Kalaria R, Lo E, Arai K, Ihara M
    • Journal Title

      Ann Clin Transl Neurol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Journal Article] 高血糖とアルツハイマー病

    • Author(s)
      猪原匡史
    • Journal Title

      医学のあゆみ

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Patent] 被験者の脳微小出血の重症化リスクを予測する方法、脳微小出血の重症化リスクの高い被験者をスクリーニングする方法、及びそれらに用いるキット2020

    • Inventor(s)
      猪原匡史,齊藤聡,服部頼都,湯原悟志,西脇森衛
    • Industrial Property Rights Holder
      猪原匡史,齊藤聡,服部頼都,湯原悟志,西脇森衛
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19K22610
  • [Patent] タキシフォリンを含有する肝線維化抑制剤及び褐色脂肪細胞活性化剤2019

    • Inventor(s)
      浅原哲子、井上隆之、田中将志、猪原匡史、齊藤聡
    • Industrial Property Rights Holder
      独立行政法人国立病院機構、他3者
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-011729
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-18H02737
  • [Patent] 認知症の予防及び/又は治療のための薬剤2016

    • Inventor(s)
      猪原匡史,齊藤聡,松本忠冒, 福島雅典
    • Industrial Property Rights Holder
      猪原匡史,齊藤聡,松本忠冒, 福島雅典
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Patent] 放射性ハロゲン標識ピリド[1,2-a]ベンゾイミダゾール誘導体化合物2015

    • Inventor(s)
      小野 正博、佐治 英郎、猪原匡史、松本博樹、関育也
    • Industrial Property Rights Holder
      小野 正博、佐治 英郎、猪原匡史、松本博樹、関育也
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-161472
    • Filing Date
      2015-08-19
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Patent] 間質流改善薬2012

    • Inventor(s)
      猪原匡史, 眞木崇州, 田口明彦
    • Industrial Property Rights Holder
      公益財団法人・先端医療振興財団
    • Industrial Property Number
      2012-135906
    • Filing Date
      2012-06-15
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Patent] 間質流改善薬2012

    • Inventor(s)
      猪原匡史、眞木崇州、田口明彦
    • Industrial Property Rights Holder
      猪原匡史、眞木崇州、田口明彦
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-06-15
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 嫌悪画像に対する聴覚刺激の影響2022

    • Author(s)
      山内美穂,岩切昌宏,権藤恭之,猪原匡史
    • Organizer
      日本光脳機能イメージング学会
    • Data Source
      KAKENHI-PROJECT-18K03167
  • [Presentation] 急性期脳卒中における病前サルコペニアと摂食嚥下予後2022

    • Author(s)
      福間一樹, 鎌田 将星, 山本 壱弥, 父川 拓朗, 馬明 克成, 阿部 宗一郎, 田中 智貴, 中奥 由里子, 西村 邦宏, 西岡 心大, 古賀 政利, 横田 千晶, 猪原 匡史
    • Organizer
      第48回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H04047
  • [Presentation] 助成研究成果報告講演 急性期脳卒中におけるサルコペニアと摂食嚥下予後2022

    • Author(s)
      福間一樹,鎌田将星,山本壱弥,馬明克成,高屋成利, 西岡心大,若林秀隆,藤島一郎,猪原匡史
    • Organizer
      第28回日本摂食嚥下リハビリテーション学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H04047
  • [Presentation] 嫌悪画像に対する聴覚刺激の効果の検討2022

    • Author(s)
      山内美穂,岩切昌宏,権藤恭之,猪原匡史
    • Organizer
      日本EMDR学会第17回学術大会
    • Data Source
      KAKENHI-PROJECT-18K03167
  • [Presentation] 嫌悪画像に対する聴覚刺激の効果の検討2022

    • Author(s)
      山内美穂,岩切昌宏,権藤恭之,猪原匡史
    • Organizer
      日本EMDR学会第17回学術大会
    • Data Source
      KAKENHI-PROJECT-22K03166
  • [Presentation] 脳卒中患者における低栄養・サルコペニア・嚥下障害の診療実態と課題-日本脳卒中学会全国アンケート結果-2022

    • Author(s)
      福間 一樹, 猪原 匡史, 山本 壱弥, 鎌田 将星, 父川 拓朗, 馬明 克成, 阿部 宗一郎, 田中 智貴, 横田 千晶, 西岡 心大, 宮井 一郎, 小笠原 邦昭, 飯原 弘二
    • Organizer
      第48回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H04047
  • [Presentation] RNF213 p.R4810K多型は頭蓋内動脈狭窄症の進行を予測する:15年長期追跡研究の成果2022

    • Author(s)
      岡﨑 周平, 吉本 武史, 渡辺光太郎, 大原 真理子, 権 泰史, 藤堂 謙一, 佐々木 勉, 猪原 匡史, 望月 秀樹
    • Organizer
      第47回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06922
  • [Presentation] Bilateral alternating stimulation of sound reduce recall contents2021

    • Author(s)
      Yamauchi M, Iida H, Nakagawara J, Ihara M.
    • Organizer
      EMDR Europe Research & Practice Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K03167
  • [Presentation] 脳内出血発症における齲蝕原性細菌の病的意義2021

    • Author(s)
      猪原匡史
    • Organizer
      日本脳卒中学会
    • Data Source
      KAKENHI-PROJECT-19K22610
  • [Presentation] 急性期被殻出血における摂食嚥下予後予測スコア2021

    • Author(s)
      福間一樹, 田中智貴, 千葉哲矢, 千葉哲矢, 古賀政利, 猪原匡史
    • Organizer
      第39回日本神経治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H04047
  • [Presentation] RNF213p.R4810K遺伝子多型を有する頭蓋内動脈狭窄症患者は動脈硬化累積リスクが低い2021

    • Author(s)
      大原 真理子,吉本 武史,岡崎 周平,権 泰史,藤堂 謙一,佐々木 勉,高杉 純司,尾原 信行,猪原 匡史,望月 秀樹
    • Organizer
      第47回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06922
  • [Presentation] Taxifolin is a novel therapeutic agent for cerebral amyloid angiopathy2020

    • Author(s)
      Satoshi Saito, Masashi Tanaka, Noriko Satoh-Asahara, Roxana O Carare1, and Masafumi Ihara
    • Organizer
      121st Meeting of the British Neuropathological Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07927
  • [Presentation] Bilateral alternating stimulation of sound reduce recall contents2020

    • Author(s)
      Yamauchi M, Iida H, Nakagawara J, Ihara M.
    • Organizer
      EMDR Europe Research & Practice Conference 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K03167
  • [Presentation] 頭蓋内動脈狭窄におけるRNF213 p.R4810K多型とMRI血管壁イメージングの関連2020

    • Author(s)
      渡邊光太郎、岡崎周平、吉本武史、藤堂謙一、佐々木勉、古賀政利,望月秀樹、猪原匡史
    • Organizer
      第45回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06922
  • [Presentation] PROGNOSTIC FACTORS OF SWALLOWING FUNCTION IN PATIENTS WITH PONTINE HEMORRHAGE2020

    • Author(s)
      Luna Kimihira, Kazuki Fukuma, Masafumi Ihara, et al.
    • Organizer
      ESO-WSO conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H04047
  • [Presentation] Taxifolin is a novel therapeutic agent for Alzheimer’s disease and cerebral amyloid angiopathy2020

    • Author(s)
      Satoshi Saito, Masashi Tanaka, Noriko Satoh-Asahara, Roxana O. Carare, Roy O. Weller, Masafumi Ihara
    • Organizer
      Alzheimer's Association International Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07927
  • [Presentation] Modeling mural cell pathology of CADASIL with disease-specific iPS cells.2020

    • Author(s)
      Masafumi Ihara
    • Organizer
      International Stroke Conference 2020
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Role of induced pluripotent stem cell in CADASIL research2019

    • Author(s)
      Masafumi Ihara
    • Organizer
      CADASIL symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Update: treatment of small vessel disease.2019

    • Author(s)
      Masafumi Ihara
    • Organizer
      2019 Asia Stroke Joint Meeting (ASJM) and Stroke Treatment and Research Society-Taiwan (STARS-Taiwan) Spring Forum
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Medical management for small vessel disease.2019

    • Author(s)
      Masafumi Ihara
    • Organizer
      International Stroke Conference 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Mechanism and management of stroke-associated comorbidities, dementia and epilepsy2019

    • Author(s)
      Masafumi Ihara
    • Organizer
      Brain & Brain PET 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Collagen-binding Streptococcus mutans tied to intracerebral hemorrhage2019

    • Author(s)
      Masafumi Ihara
    • Organizer
      日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K22610
  • [Presentation] 虫歯・歯周病と脳卒中・認知症の関連(RAMESSES研究)2019

    • Author(s)
      猪原匡史
    • Organizer
      日本神経治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K22610
  • [Presentation] Clinical trial on human lymphatic drainage system.2018

    • Author(s)
      Masafumi Ihara
    • Organizer
      XXI Symposium Neuroradiologicum (SNR2018)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Bench to bedside: using mouse models to identify new treatment approaches for dementia.2018

    • Author(s)
      Masafumi Ihara
    • Organizer
      CINP2018 (31st The International College of Neuropsychopharmacology)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Cerebral hypoperfusion.2018

    • Author(s)
      Masafumi Ihara
    • Organizer
      16th Asian Oceanian Congress of Neurology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Pathogenesis of sporadic small vessel disease.2018

    • Author(s)
      Masafumi Ihara
    • Organizer
      2nd Asia-Pacific Aging Protection Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] Dental microbes and stroke/dementia2017

    • Author(s)
      Masafumi Ihara
    • Organizer
      Brain Ageing and Dementia in LIMICS
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04670
  • [Presentation] 慢性脳低灌流はタウ病理を加速させる: 脳血管アミロイド血管症とタウとの関連2017

    • Author(s)
      齊藤聡、 山本由美、 高橋良輔、 猪原匡史
    • Organizer
      脳循環代謝学会
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] cnm遺伝子陽性Streptococcus mutansと脳微小出血の分布との関連2017

    • Author(s)
      殿村 修一, 齊藤 聡, 峰松 一夫, 猪原 匡史
    • Organizer
      脳ドック学会
    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Presentation] Vascular Dementia2017

    • Author(s)
      Masafumi Ihara
    • Organizer
      International Stroke Conference
    • Place of Presentation
      Houston, USA
    • Year and Date
      2017-02-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Presentation] Dental microbes and stroke/dementia.2016

    • Author(s)
      Masafumi Ihara
    • Organizer
      Brain Ageing and Dementia in LIMICS 2016
    • Place of Presentation
      Nairobi, Kenya
    • Year and Date
      2016-12-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Presentation] 脳卒中の新たな危険因子-口腔内感染-.2016

    • Author(s)
      猪原匡史
    • Organizer
      日本神経学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K14573
  • [Presentation] Experimental evidence linking vascular factors to Alzheimer's disease2015

    • Author(s)
      Masafumi Ihara
    • Organizer
      Alzheimer's Association International Conference (AAIC)
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2015-07-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] Animal Model of VCI2015

    • Author(s)
      Masafumi Ihara
    • Organizer
      Vas-Cog International
    • Place of Presentation
      Tokyo
    • Year and Date
      2015-09-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] Vascular Cognitive Impairment2015

    • Author(s)
      猪原匡史
    • Organizer
      第20回認知神経科学会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] ドラッグ・リポジショニングの手法を用いた軽&#64001;認知障害に対する創薬戦&#63862;2015

    • Author(s)
      猪原匡史
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] Bone morphogenetic protein‐4 expression by pericytes correlates with white matter damage in dementing disorders2015

    • Author(s)
      Masafumi Ihara
    • Organizer
      Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kobe
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] 血管病を標的とした認知症治療2015

    • Author(s)
      猪原匡史
    • Organizer
      第5回認知症予防学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04271
  • [Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題2013

    • Author(s)
      Ihara M
    • Organizer
      Novel mechanism and therapy to treat patient with dementia. Neuro2013
    • Place of Presentation
      京都
    • Year and Date
      2013-06-21
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Symposium S(4) -1. Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment (VCI) . Cerebral amyloid angiopathy and cognitive impairment2013

    • Author(s)
      Ihara M
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2013-06-01
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Bench to bedside : using mouse models to identify new treatment approaches for Alzheimer' s disease2013

    • Author(s)
      Ihara M
    • Organizer
      Invited lecture : 19th Southampton Neuroscience Group (SoNG) Meeting
    • Place of Presentation
      Southampton, UK
    • Year and Date
      2013-09-19
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment2013

    • Author(s)
      Ihara M
    • Organizer
      Minisymposium (Animal models of VCI) . Vas-Cog2013
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2013-06-26
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment2013

    • Author(s)
      Ihara M
    • Organizer
      Plenary session (Special session on animal models of VCI) . Vas-Cog2013
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2013-06-26
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Animal models for vascular cognitive impairment due to large vessel disease. Stroke Symposium in National University of Singapore2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Stroke Symposium in National University of Singapore
    • Place of Presentation
      Singapore(招待講演)
    • Year and Date
      2011-10-31
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Animal models forvascular cognitive impairment due tolarge vessel disease2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Stroke Symposiumin National University of Singapore(Invited lecture)
    • Place of Presentation
      Singapore
    • Year and Date
      2011-10-31
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] βアミロイドの血管依存性クリアランス2011

    • Author(s)
      猪原匡史
    • Organizer
      日本認知症学会学術集会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Angiogenic andvasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Vas-Cog
    • Place of Presentation
      Lille, France
    • Year and Date
      2011-09-14
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] 脳低灌流によりβアミロイドの血管依存性クリアランスが障害される2011

    • Author(s)
      猪原匡史, 他
    • Organizer
      日本認知症学会学術集会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] モントリオール認知評価法MoCAはMMSEよりも皮質下血管性認知障害の検出感度が高い2011

    • Author(s)
      猪原匡史, 岡本洋子, 伊東秀文, 高橋良輔
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] モントリオール認知評価法MoCAはMMSEよりも皮質下血管性認知障害の検出感度が高い2011

    • Author(s)
      猪原匡史
    • Organizer
      日本神経学会総会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 脳低灌流によりβアミロイドの血管依存性クリアランスが障害される2011

    • Author(s)
      猪原匡史, 岡本洋子, 眞木崇州, 鷲田和夫, 伊東秀文, 冨本秀和, 高橋良輔
    • Organizer
      第30回日本認知症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] βアミロイドの血管依存性クリアランス2011

    • Author(s)
      猪原匡史
    • Organizer
      第30回日本認知症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] Angiogenic and vasoprotectivc effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Vas-Cog2011
    • Place of Presentation
      France
    • Year and Date
      2011-09-14
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Poster review session.2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      Vas-Cog
    • Place of Presentation
      Lille, France
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] Animal models for vascular cognitive impairment due to large vessel disease2011

    • Author(s)
      Masafumi Ihara
    • Organizer
      STROKE SYMPOSIUM
    • Place of Presentation
      Singapore(CELS Auditorium)
    • Year and Date
      2011-10-31
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] 皮質下血管性認知症患者におけるモントリオール認知評価スコアと身体活動度との相関2011

    • Author(s)
      猪原匡史
    • Organizer
      第30回日本認知症学会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-23650182
  • [Presentation] CADASIL側頭極病変の成因に関する病理学的研究2010

    • Author(s)
      猪原匡史, 山本由美, ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] シロスタゾールの血液脳関門保護効果:一過性局所脳虚血モデルから得られたエビデンス2010

    • Author(s)
      猪原匡史
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] Animal models to study Stroke and VCI.2010

    • Author(s)
      Masafumi Ihara
    • Organizer
      Annual Neurosciences Conference in Eastern Africa
    • Place of Presentation
      Nairobi, Kenya
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] シロスタゾールの血液脳関門保護効果-一過性局所脳虚血モデルにおけるVirchow血栓形成3要因への作用について-2010

    • Author(s)
      猪原匡史
    • Organizer
      日本脳循環代謝学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] 混合型認知症の位置づけ, Vascular cognitive impairment(VCI)2010

    • Author(s)
      猪原匡史
    • Organizer
      日本認知症学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] A Mouse Model Characterizing Features of Vascular Dementia with Hippocampal Atrophy2010

    • Author(s)
      Masafumi Ihara
    • Organizer
      International Congress of Neuropathology (ICN2010)
    • Place of Presentation
      Salzburg, Austria
    • Year and Date
      2010-09-13
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] 脳血管障害に基づく認知機能障害の病態2010

    • Author(s)
      猪原匡史
    • Organizer
      日本脳卒中学会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-04-15
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] 海馬萎縮を伴う血管性認知症の新規モデルマウス2010

    • Author(s)
      猪原匡史
    • Organizer
      日本脳循環代謝学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-22650073
  • [Presentation] シロスタゾールによる血管依存性βアミロイドクリアランスの促進.

    • Author(s)
      猪原匡史
    • Organizer
      脳循環代謝学会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] シンポジウム5「血管性認知障害」血管性認知障害の病態-モデル動物を用いて明らかとなった知見-

    • Author(s)
      猪原匡史
    • Organizer
      第39回日本脳卒中学会総会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Plenary session (Special session on animal models of VCI). Vas-Cog2013
    • Place of Presentation
      Toronto
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Minisymposium (Animal models of VCI). Vas-Cog2013
    • Place of Presentation
      Toronto
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 「血管病としての認知症」

    • Author(s)
      猪原匡史
    • Organizer
      Vas-Cog Japan
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] 血管病としての認知症~その制圧へ向けた試み~

    • Author(s)
      猪原匡史
    • Organizer
      第3回VAS-COG Japan 2012
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] シンポジウム5「血管性認知障害」血管性認知障害の病態-モデル動物を用いて明らかとなった知見-

    • Author(s)
      猪原匡史
    • Organizer
      第39回日本脳卒中学会総会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 「長寿遺伝子」SIRT1はeNOSを脱アセチル化することで脳低灌流侵襲に対する抵抗性を賦与する

    • Author(s)
      猪原匡史
    • Organizer
      脳卒中学会
    • Place of Presentation
      広島
    • Year and Date
      2015-03-26 – 2015-03-29
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical

    • Author(s)
      Masafumi Ihara
    • Organizer
      3rd CAA meeting (Plenary lecture)
    • Place of Presentation
      Leiden
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Symposium S(4)-1.Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment (VCI).Cerebral amyloid angiopathy and cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Plenary session (Special session on animal models of VCI). Vas-Cog2013
    • Place of Presentation
      Toronto
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 「認知症の発症にかかわる脳血管の機能」.

    • Author(s)
      猪原匡史
    • Organizer
      脳心血管抗加齢研究会2013
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Bench to bedside: using mouse models to identify new treatment approaches for Alzheimer’s disease.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Invited lecture: 19th Southampton Neuroscience Group (SoNG) Meeting
    • Place of Presentation
      Southampton
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 小血管病における虚血性線条体障害:11C-フルマゼニルPETによる解析

    • Author(s)
      猪原匡史
    • Organizer
      第5回J-CAN (Japanese Consortium for Age-related Neurodegenerative disorders) 2012
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Bench to bedside: using mouse models to identify new treatment approaches for Alzheimer’s disease.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Invited lecture: 19th Southampton Neuroscience Group (SoNG) Meeting
    • Place of Presentation
      Southampton
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] 認知症患者における抗血栓療法の有効性と安全性に関する分子病理学的検討

    • Author(s)
      猪原匡史
    • Organizer
      第37回日本脳卒中学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 「血管病としての認知症」

    • Author(s)
      猪原匡史
    • Organizer
      Vas-Cog Japan
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 「認知症の発症にかかわる脳血管の機能」.

    • Author(s)
      猪原匡史
    • Organizer
      脳心血管抗加齢研究会2013
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical

    • Author(s)
      Masafumi Ihara
    • Organizer
      World Stroke Congress
    • Place of Presentation
      Brazilia
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] シロスタゾールによる血管依存性βアミロイドクリアランスの促進.

    • Author(s)
      猪原匡史
    • Organizer
      脳循環代謝学会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Novel mechanism and therapy to treat patient with dementia. Neuro2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] 認知症における脳血管病変

    • Author(s)
      猪原匡史
    • Organizer
      第3回VAS-COG Japan 2012
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Symposium S(4)-1.Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment (VCI).Cerebral amyloid angiopathy and cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] シンポジウム1.血管性認知症の最先端「血管性認知症とAlzheimer病理」

    • Author(s)
      猪原匡史
    • Organizer
      第31回日本認知症学会学術集会
    • Place of Presentation
      つくば
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Novel mechanism and therapy to treat patient with dementia. Neuro2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] 皮質下血管性認知症患者におけるモントリオール認知評価スコアと身体活動度との相関

    • Author(s)
      猪原匡史
    • Organizer
      第53回日本神経学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390233
  • [Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment.

    • Author(s)
      Masafumi Ihara.
    • Organizer
      Minisymposium (Animal models of VCI). Vas-Cog2013
    • Place of Presentation
      Toronto
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640031
  • [Presentation] Animal models of brain hypoperfusion and cognitive impairment

    • Author(s)
      Masafumi Ihara
    • Organizer
      BRAIN AGEING AND DEMENTIA IN DEVELOPING COUNTRIES 2012
    • Place of Presentation
      Nairobi
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390233
  • 1.  Satoh-Asahara Noriko (80373512)
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  • 2.  仲野 和彦 (00379083)
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  • 3.  齊藤 聡 (40732996)
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  • 4.  二宮 利治 (30571765)
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  • 5.  西村 邦宏 (70397834)
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  • 6.  TOMIMOTO Hidekazu (80324648)
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  • 7.  ONO Masahiro (80336180)
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  • 8.  Yamauchi Miho (10443491)
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  • 83.  田中 都
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  • 84.  菅波 孝祥
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