Ihara Masafumi 猪原匡史

… Alternative Names

IHARA Masafumi 猪原匡史

猪原匡史イハラマサフミ

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Researcher Number	00372590
Other IDs	https://orcid.org/0000-0002-7102-4048
Affiliation (Current)	2024: 国立研究開発法人国立循環器病研究センター, 病院, 部長
Affiliation (based on the past Project Information) *help	2024: 国立研究開発法人国立循環器病研究センター, その他部局等, その他 2016 – 2024: 国立研究開発法人国立循環器病研究センター, 病院, 部長 2016: 国立循環器病研究センター, 脳血管内科, 医長 2015: 国立研究開発法人国立循環器病研究センター, 病院, 医長 2013 – 2014: 独立行政法人国立循環器病研究センター, 病院, 医長 … More 2012: 公益財団法人先端医療振興財団, 先端医療センター再生医療研究部, 副部長 2011: 京都大学, 医学研究科, 助教 2010 – 2011: 京都大学, 医学(系)研究科(研究院), 助教 2004: 京大, 医学(系)研究科(研究院) Less
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / Basic Section 59010:Rehabilitation science-related / Medium-sized Section 52:General internal medicine and related fields / Nerve anatomy/Neuropathology / Medium-sized Section 57:Oral science and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Pathobiological dentistry/Dental radiology / Neurology / Structural biochemistry Except Principal Investigator Basic Section 52010:General internal medicine-related … More / Basic Section 10030:Clinical psychology-related / Basic Section 56010:Neurosurgery-related / Basic Section 46020:Anatomy and histopathology of nervous system-related / Neurosurgery / Radiation science Less
Keywords	Principal Investigator 脳卒中 / 齲蝕原性細菌 / 口腔内細菌 / 摂食嚥下障害 / サルコペニア / 脳内出血 / 脳微小出血 / 脳出血 / ミュータンス菌 / 脳循環障害 … More / 脳神経疾患 / 血管性認知症 / シロスタゾール / アルツハイマー病 / 歯科医科連携 / マトリソーム / 摂食嚥下機能障害 / 高齢者 / 嚥下障害 / 分子標的 / Cnm / コラーゲン接着因子 / コラーゲン / 細菌 / 循環器・高血圧 / 歯学 / 歯科衛生 / アフリカ / コラーゲン結合性 / 連鎖球菌 / 脳内微小出血 / アミロイドβ / 抗糖化 / アミロイド / 抗糖化薬 / オリゴマー / 認知症 / 病理学 / 痴呆 / 脳・神経 / 神経科学 / 脳アミロイド血管症 / タウ / 抗糖化作用 / タキシフォリン / レスベラトロール / 脳循環予備能 / 一酸化窒素 / 両側総頸動脈狭窄術 / Sirt1 / 血液脳関門 / 内皮型一酸化窒素合成酵素 / 脳梗塞 / SIRT1 / サーチュイン / 長寿遺伝子 / Notch3 / iPS細胞 / CADASIL / Tg-SwDIマウス / モデルマウス / 微小梗塞 / 医師主導治験 / 臨床試験 / βアミロイド / アミロイド血管症 / ナノメディシン / ドラッグディリバリー / オートファジー / 脳虚血 … More Except Principal Investigator 糖尿病 / TREM2 / 肥満 / 認知症 / タキシフォリン / 炎症 / ミクログリア / 脳血管障害 / RNF213 / 単球・ミクログリア / 治療戦略 / 早期予知バイオマーカー / 抑うつ / 人口知能 / Patient Health Record / 人工知能 / 心臓病 / 脳卒中 / PHR / コグニティブフレイル / 糖尿病性認知症 / NIRS / CGM / 心不全 / 血糖変動 / 単級・ミクログリア / アミロイドβ / 予防戦略 / 脳アミロイド血管症 / 血管合併症 / 単球 / 感受性遺伝子 / 脳梗塞 / 頭蓋内血管狭窄 / もやもや病 / 脳動脈狭窄 / 遺伝子解析 / 動脈硬化 / 頭蓋内動脈狭窄 / 多施設共同前向き観察研究 / 血管壁イメージング / 単球機能 / 脳神経ネットワーク / 心理リハビリテーション / 脳内神経ネットワーク / 臨床 / 内科 / 脳神経疾患 / 研究者主導型試験 / 国際共同無作為化比較試験 / 降圧薬 / 血圧 / 配合剤 / アジア / 民族差 / 性差 / 研究者主導型臨床試験 / 降圧療法 / 高血圧 / 脳出血 / βアミロイド / 診断 / 金属錯体 / イメージング / 脳アミロイドアンギオパチー Less

脳筋連関・TREM2に着目した糖尿病性認知症・コグニティブフレイルの予防戦略開発
- Principal Investigator
  
  浅原哲子 (佐藤哲子)
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
Collaborative dental-medical research on the mechanism of intracerebral hemorrhage via cerebrovascular matrisome injury by oral bacteriaPrincipal Investigator
- Principal Investigator
  
  猪原匡史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  National Cardiovascular Center Research Institute
日韓台合同CADASIL1000人レジストリと国際治験基盤の構築Principal Investigator
- Principal Investigator
  
  猪原匡史
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  National Cardiovascular Center Research Institute
Prognostic role of white matter lesion topography in cerebrovascular disordersPrincipal Investigator
- Principal Investigator
  
  猪原匡史
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  National Cardiovascular Center Research Institute
Construction of an evaluation system for feeding and swallowing disorders and sarcopenia after stroke and search for key molecules in the brain-gut-muscle linkagePrincipal Investigator
- Principal Investigator
  
  猪原匡史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Cardiovascular Center Research Institute
抑うつと前頭前野機能への両側性刺激の効果に関する基礎的fNIRS研究
- Principal Investigator
  
  山内美穂
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 10030:Clinical psychology-related
- Research Institution
  National Cardiovascular Center Research Institute
糖尿病合併認知症の新規予防・治療戦略：TREM2を標的としたミクログリア形質改善
- Principal Investigator
  
  田中将志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Health Science University
脳卒中・心臓病のCircular Healthcare Systemに関する研究
- Principal Investigator
  
  飯原弘二
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Cardiovascular Center Research Institute
脂肪ー脳連関・TREM2に着目した糖尿病・肥満の新規認知症評価系と予防戦略の開発
- Principal Investigator
  
  浅原哲子 (佐藤哲子)
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
脳血管障害・肥満の共通基盤候補としてのRNF213遺伝子多型と機能的意義の解明
- Principal Investigator
  
  野口倫生
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  National Cardiovascular Center Research Institute
3000人規模コホートによる新世代CGMを用いたIGTの心血管病発症機構の解明
- Principal Investigator
  
  細田公則
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  National Cardiovascular Center Research Institute
Dysphagia severity and decision making algorithm after acute stoke in the elderlyPrincipal Investigator
- Principal Investigator
  
  Ihara Masafumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Cardiovascular Center Research Institute
RNF213-related vasculopathy and stroke: mechanisms and treatment strategies
- Principal Investigator
  
  岡崎周平
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  Osaka University
Pathological Significance of TREM2 in Obesity/Diabetes-Related Cognitive Impairment through the Brain-Adipose Tissue Axis
- Principal Investigator
  
  TANAKA Masashi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Health Science University
A study to elucidate the mechanism of intracerebral heorrhage induced by collagen-binding Streptococcus mutans and to develop a novel preventive therapyPrincipal Investigator
- Principal Investigator
  
  Ihara Masafumi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  National Cardiovascular Center Research Institute
Fundamental research on the effect of auditory bilateral stimulation on depressive symptoms
- Principal Investigator
  
  Yamauchi Miho
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 10030:Clinical psychology-related
- Research Institution
  National Cardiovascular Center Research Institute
Development of predictive indicators and treatment strategies for dementia associated with diabetes and obesity focusing TREM2 and monocyte function
- Principal Investigator
  
  Satoh-Asahara Noriko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
Triple therapy prevention of Recurrent Intracerebral Disease EveNts Trial
- Principal Investigator
  
  Toyoda Kazunori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  National Cardiovascular Center Research Institute
Establishment of international liaison between medical doctors and dentists for the purpose of reduction of stroke in Nigeria and KenyaPrincipal Investigator
- Principal Investigator
  
  Ihara Masafumi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  National Cardiovascular Center Research Institute
Study to understand mechanism of hemorrhagic stroke induced by oral bacteriaPrincipal Investigator
- Principal Investigator
  
  IHARA MASAFUMI
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  National Cardiovascular Center Research Institute
Development of anti-glycosylation agents for Alzheimer diseasePrincipal Investigator
- Principal Investigator
  
  IHARA MASAFUMI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  National Cardiovascular Center Research Institute
Development of nuclear medical imaging probes targeting cerebral amyloid antipathy
- Principal Investigator
  
  Ono Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
A study to elucidate the mechanism by which the longevity gene product SIRT1 confers neuroprotectionPrincipal Investigator
- Principal Investigator
  
  IHARA Masafumi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  National Cardiovascular Center Research Institute
Regenerative therapy for Alzheimer's disease and cerebral amyloid angiopathyPrincipal Investigator
- Principal Investigator
  
  IHARA Masafumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  National Cardiovascular Center Research Institute
  Foundation for Biomedical Research and Innovation
  Kyoto University
Exploration of treatment of hereditary vascular dementia CADASIL using patient-derived iPS cells and its model micePrincipal Investigator
- Principal Investigator
  
  IHARA Masafumi
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
融合ナノプローブ薬剤送達システムを用いた脳虚血巣選択的オートファジー制御への挑戦Principal Investigator
- Principal Investigator
  
  猪原匡史
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
セプチン/脂質によるαシヌクレインポリマー/フィラメント形成機序に関する検討Principal Investigator
- Principal Investigator
  
  猪原匡史
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University

[Book] Annual Review神経２０１９2019
- Author(s)
  殿村修一，猪原匡史
- Total Pages
  326
- Publisher
  中外学社
- Data Source
  KAKENHI-PROJECT-17H04670
[Book] モデル動物利用マニュアル.疾患モデルの作製と利用一循環器疾患2010
- Author(s)
  北徹, 堀内久徳, 柳田素子, 猪原匡史, 冨本秀和, 並河徹編
- Total Pages
  486
- Publisher
  (株)エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-22650073
[Book] 慢性脳低灌流モデル.北徹, 堀内久徳, 柳田素子, 猪原匡史, 冨本秀和, 並河徹編「モデル動物利用マニュアル. 疾患モデルの作製と利用-循環器疾患」(株)
- Author(s)
  猪原匡史, 冨本秀和
- Total Pages
  486
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-23390233
[Journal Article] Novel Therapeutic Potentials of Taxifolin for Obesity-Induced Hepatic Steatosis, Fibrogenesis, and Tumorigenesis2023
- Author(s)
  Inoue Takayuki、Fu Bin、Nishio Miwako、Tanaka Miyako、Kato Hisashi、Tanaka Masashi、Itoh Michiko、Yamakage Hajime、Ochi Kozue、Ito Ayaka、Shiraki Yukihiro、Saito Satoshi、Ihara Masafumi、Nishimura Hideo、Kawamoto Atsuhiko、Inoue Shian、Saeki Kumiko、Enomoto Atsushi、Suganami Takayoshi、Satoh-Asahara Noriko
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 2 Pages: 350-350
- DOI
  10.3390/nu15020350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08526, KAKENHI-PROJECT-21K08571, KAKENHI-PROJECT-22K07456, KAKENHI-PROJECT-22K08667, KAKENHI-PROJECT-22K11700, KAKENHI-PROJECT-22K11720, KAKENHI-PROJECT-22K19524, KAKENHI-PROJECT-22K19723, KAKENHI-PROJECT-21K17557, KAKENHI-PROJECT-19KK0249, KAKENHI-PUBLICLY-21H05625, KAKENHI-PROJECT-20H03447, KAKENHI-PROJECT-21H02835, KAKENHI-PROJECT-19K07905, KAKENHI-PROJECT-19K07927, KAKENHI-PUBLICLY-22H04806
[Journal Article] <i>RNF213</i> p.R4810K Variant Carriers with Intracranial Arterial Stenosis Have a Low Atherosclerotic Burden2022
- Author(s)
  Ohara Mariko、Yoshimoto Takeshi、Okazaki Shuhei、Gon Yasufumi、Todo Kenichi、Sasaki Tsutomu、Takasugi Junji、Ohara Nobuyuki、Ihara Masafumi、Mochizuki Hideki
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 29 Issue: 11 Pages: 1655-1662
- DOI
  10.5551/jat.63379
- NAID
  130008134294
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2022-11-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06922
[Journal Article] Effect of the RNF213 p.R4810K Variant on the Progression of Intracranial Artery Stenosis2022
- Author(s)
  Okazaki Shuhei、Yoshimoto Takeshi、Ohara Mariko、Takagaki Masatoshi、Nakamura Hajime、Watanabe Kotaro、Gon Yasufumi、Todo Kenichi、Sasaki Tsutomu、Araki Hiroyuki、Yamada Tomomi、Manabe Shirou、Kishima Haruhiko、Ihara Masafumi、Mochizuki Hideki
- Journal Title
  
  Neurology Genetics
  
  Volume: 8 Issue: 5
- DOI
  10.1212/nxg.0000000000200029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06922
[Journal Article] Taxifolin: A Potential Therapeutic Agent for Cerebral Amyloid Angiopathy2021
- Author(s)
  Saito Satoshi、Tanaka Masashi、Satoh-Asahara Noriko、Carare Roxana Octavia、Ihara Masafumi
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12 Pages: 643357-643357
- DOI
  10.3389/fphar.2021.643357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07927, KAKENHI-PROJECT-18H02737, KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-21H02835
[Journal Article] A Nationwide Multi-Center Questionnaire Survey on the Real-World State and Issues Regarding Post-Stroke Complications in Japan.2021
- Author(s)
  Ikeda S, Washida K, Tanaka T, Kitajima E, Chiba T, Fukuma K, Yoshimoto T, Saito S, Hattori Y, Ihara M.
- Journal Title
  
  J Stroke Cerebrovasc Dis.
  
  Volume: 30(4) Issue: 4 Pages: 105656-105656
- DOI
  10.1016/j.jstrokecerebrovasdis.2021.105656
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16888, KAKENHI-PROJECT-20H04047
[Journal Article] Phase angle from bioelectrical impedance analysis is a useful indicator of muscle quality2021
- Author(s)
  Akamatsu Yasunori、Kusakabe Toru、Arai Hiroshi、Yamamoto Yuji、Nakao Kazuwa、Ikeue Kentaro、Ishihara Yuki、Tagami Tetsuya、Yasoda Akihiro、Ishii Kojiro、Satoh‐Asahara Noriko
- Journal Title
  
  Journal of Cachexia, Sarcopenia and Muscle
  
  Volume: 13 Issue: 1 Pages: 180-189
- DOI
  10.1002/jcsm.12860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-21H02835, KAKENHI-PROJECT-18K11093, KAKENHI-PROJECT-21K11691, KAKENHI-PROJECT-20K19561
[Journal Article] RNF213 p.R4810K (c.14429G > A) Variant Determines Anatomical Variations of the Circle of Willis in Cerebrovascular Disease2021
- Author(s)
  Eto Futoshi、Yoshimoto Takeshi、Okazaki Shuhei、Nishimura Kunihiro、Ogura Shiori、Yamaguchi Eriko、Fukuma Kazuki、Saito Satoshi、Washida Kazuo、Koga Masatoshi、Toyoda Kazunori、Morimoto Takaaki、Maruyama Hirofumi、Koizumi Akio、Ihara Masafumi
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 13 Pages: 681743-681743
- DOI
  10.3389/fnagi.2021.681743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19K06922
[Journal Article] Late Neurological Deterioration after Acute Intracerebral Hemorrhage: A post hoc Analysis of the ATACH-2 Trial2020
- Author(s)
  Okazaki Shuhei、Yamamoto Haruko、Foster Lydia、Fukuda-Doi Mayumi、Koga Masatoshi、Ihara Masafumi、Toyoda Kazunori、Palesch Yuko?Y.、Qureshi Adnan?I.
- Journal Title
  
  Cerebrovascular Diseases
  
  Volume: 49 Issue: 1 Pages: 26-31
- DOI
  10.1159/000506117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04308, KAKENHI-PROJECT-17H04670
[Journal Article] Microbiota in cerebrovascular disease: A key player and future therapeutic target2020
- Author(s)
  Tonomura Shuichi、Ihara Masafumi、Friedland Robert P
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: n.d. Issue: 7 Pages: 1368-1380
- DOI
  10.1177/0271678x20918031
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22610, KAKENHI-PROJECT-20J15262
[Journal Article] D-dimer level and outcome of minor ischemic stroke with large vessel occlusion2020
- Author(s)
  Sato Takeo、Sato Shoichiro、Yamagami Hiroshi、Komatsu Teppei、Mizoguchi Tadataka、Yoshimoto Takeshi、Takagi Masahito、Ihara Masafumi、Koga Masatoshi、Iwata Hiroyoshi、Matsushima Masato、Toyoda Kazunori、Iguchi Yasuyuki
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 413 Pages: 116814-116814
- DOI
  10.1016/j.jns.2020.116814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Oral carriage of Streptococcus mutans harboring the cnm gene is related to an increased incidence of cerebral microbleeds2020
- Author(s)
  Hosoki S, Saito S, Tonomura S, Ishiyama H, Yoshimoto T, Ikeda S, Ikenouchi H, Yamamoto Y, Hattori Y, Miwa K, Friedland RP, Carare RO, Nakahara J, Suzuki N, Koga M, Toyoda K, Nomura R, Nakano K, Takegami M, Ihara M.
- Journal Title
  
  Stroke
  
  Volume: 51 Issue: 12 Pages: 3632-3639
- DOI
  10.1161/strokeaha.120.029607
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03010, KAKENHI-PROJECT-19J00106, KAKENHI-PROJECT-19K22610, KAKENHI-PROJECT-20J15262
[Journal Article] 齲歯・歯周病と脳卒中・認知症の関連（RAMESSES研究）2020
- Author(s)
  猪原匡史，齊藤聡，服部頼都，細木聡，山本由美，殿村修一
- Journal Title
  
  神経治療学
  
  Volume: n.d.
- NAID
  130007981249
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22610
[Journal Article] Statin treatment can reduce incidence of early seizure in acute ischemic stroke: A propensity score analysis2020
- Author(s)
  Matsubara Soichiro、Tanaka Tomotaka、Tomari Shinya、Fukuma Kazuki、Ishiyama Hiroyuki、Abe Soichiro、Arimizu Takuro、Yamaguchi Yoshitaka、Ogata Soshiro、Nishimura Kunihiro、Koga Masatoshi、Ando Yukio、Toyoda Kazunori、Ihara Masafumi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1968-1968
- DOI
  10.1038/s41598-020-58652-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-19K16888
[Journal Article] Visualizing prolonged hyperperfusion in post-stroke epilepsy using postictal subtraction SPECT2020
- Author(s)
  Kazuki Fukuma, Katsufumi Kajimoto, Tomotaka Tanaka, Shigetoshi Takaya, Katsuya Kobayashi, Akihiro Shimotake, Riki Matsumoto, Akio Ikeda, Kazunori Toyoda, Masfumi Ihara
- Journal Title
  
  Journal of Cerebral Blood Flow and Metabolism
  
  Volume: - Issue: 1 Pages: 146-156
- DOI
  10.1177/0271678x20902742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-16K09715, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-19K16888, KAKENHI-PROJECT-19H03574, KAKENHI-PROJECT-20K21573
[Journal Article] Human iPS cell-derived mural cells as an in vitro model of hereditary cerebral small vessel disease2020
- Author(s)
  Yamamoto Yumi、Kojima Katsutoshi、Taura Daisuke、Sone Masakatsu、Washida Kazuo、Egawa Naohiro、Kondo Takayuki、Minakawa Eiko N.、Tsukita Kayoko、Enami Takako、Tomimoto Hidekazu、Mizuno Toshiki、Kalaria Raj N.、Inagaki Nobuya、Takahashi Ryosuke、Harada-Shiba Mariko、Ihara Masafumi、Inoue Haruhisa
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 38-38
- DOI
  10.1186/s13041-020-00573-w
- NAID
  120006818682
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08514, KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-17K09880, KAKENHI-PROJECT-18K15347, KAKENHI-PROJECT-20K07883, KAKENHI-PROJECT-18K07058, KAKENHI-PROJECT-19J40007
[Journal Article] アフリカでの脳卒中低減を目指した医科―歯科国際連携の試み．2020
- Author(s)
  殿村修一，井上学，角田良介，野村良太，仲野和彦，猪原匡史
- Journal Title
  
  脳卒中
  
  Volume: 42 Pages: 107-108
- NAID
  130007815617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Potential Therapeutic Approaches for Cerebral Amyloid Angiopathy and Alzheimer’s Disease2020
- Author(s)
  Tanaka Masashi、Saito Satoshi、Inoue Takayuki、Satoh-Asahara Noriko、Ihara Masafumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 6 Pages: 1992-1992
- DOI
  10.3390/ijms21061992
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07927, KAKENHI-PROJECT-19K11760, KAKENHI-PROJECT-19J00106, KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-18H02737
[Journal Article] Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia2020
- Author(s)
  Uemura Maiko T.、Maki Takakuni、Ihara Masafumi、Lee Virginia M. Y.、Trojanowski John Q.
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 12 Pages: 80-80
- DOI
  10.3389/fnagi.2020.00080
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22610, KAKENHI-PROJECT-17H04670
[Journal Article] Concentrations of dabigatran administered after acute ischemic stroke2020
- Author(s)
  Wada Shinichi、Inoue Manabu、Matsuki Takayuki、Okata Takuya、Kumamoto Masaya、Tagawa Naoki、Yoshimura Sohei、Okamoto Akira、Miyata Toshiyuki、Ihara Masafumi、Toyoda Kazunori、Koga Masatoshi
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 411 Pages: 116704-116704
- DOI
  10.1016/j.jns.2020.116704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Large aortic arch plaques correlate with CHADS2 and CHA2DS2-VASc scores in cryptogenic stroke2019
- Author(s)
  Ueno Yuji、Tateishi Yohei、Doijiri Ryosuke、Kuriki Ayako、Shimizu Takahiro、Kikuno Muneaki、Shimada Yoshiaki、Takekawa Hidehiro、Yamaguchi Eriko、Koga Masatoshi、Kamiya Yuki、Ihara Masafumi、Tsujino Akira、Hirata Koichi、Toyoda Kazunori、Hasegawa Yasuhiro、Hattori Nobutaka、Urabe Takao
- Journal Title
  
  Atherosclerosis
  
  Volume: 284 Pages: 181-186
- DOI
  10.1016/j.atherosclerosis.2019.03.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] The rise and rise of cerebral small vessel disease: implications for vascular cognitive impairment and dementia2019
- Author(s)
  Kalaria Raj N、Hase Yoshiki、Ihara Masafumi
- Journal Title
  
  Future Neurology
  
  Volume: 14 Issue: 2
- DOI
  10.2217/fnl-2019-0004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Association of <i>CYP2C19</i> Polymorphisms With Clopidogrel Reactivity and Clinical Outcomes in Chronic Ischemic Stroke2019
- Author(s)
  Tanaka Tomotaka、Yamagami Hiroshi、Ihara Masafumi、et al.
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 6 Pages: 1385-1393
- DOI
  10.1253/circj.CJ-18-1386
- NAID
  130007652780
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-05-24
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Stroke, cerebrovascular diseases and vascular cognitive impairment in Africa2019
- Author(s)
  Akinyemi Rufus O.、Owolabi Mayowa O.、Ihara Masafumi、Damasceno Albertino、Ogunniyi Adesola、Dotchin Catherine、Paddick Stella-Maria、Ogeng’o Julius、Walker Richard、Kalaria Raj N.
- Journal Title
  
  Brain Research Bulletin
  
  Volume: 145 Pages: 97-108
- DOI
  10.1016/j.brainresbull.2018.05.018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Clinical and Radiological Characteristics of Intracranial Artery Dissection Using Recently Proposed Diagnostic Criteria2019
- Author(s)
  Nakamura Y, Yamaguchi Y, Makita N, Morita Y, Ide T, Wada S, Mizoguchi T, Ikenouchi H, Miwa K, Yi K, Irie K, Shimohama S, Ihara M, Toyoda K, Koga M
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: Epub Issue: 6 Pages: 30063-1
- DOI
  10.1016/j.jstrokecerebrovasdis.2019.02.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09485, KAKENHI-PROJECT-16H05279, KAKENHI-PROJECT-17H04670
[Journal Article] Balloon-like Mobile Plaque in the Innominate Artery: Ultrasonographic and Pathological Perspectives of Repetitive Embolism2019
- Author(s)
  Ikenouchi Hajime、Washida Kazuo、Yoshimoto Takeshi、Fukuma Kazuki、Saito Satoshi、Inoue Yosuke、Matsuda Hitoshi、Ihara Masafumi
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 28 Issue: 7 Pages: e95-e97
- DOI
  10.1016/j.jstrokecerebrovasdis.2019.04.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-19J00106
[Journal Article] Novel Therapeutic Potentials of Taxifolin for Amyloid-β-associated Neurodegenerative Diseases and Other Diseases: Recent Advances and Future Perspectives2019
- Author(s)
  Tanaka Masashi、Saito Satoshi、Inoue Takayuki、Satoh-Asahara Noriko、Ihara Masafumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 9 Pages: 2139-2139
- DOI
  10.3390/ijms20092139
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07927, KAKENHI-PROJECT-19K11760, KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-18H02737, KAKENHI-PROJECT-19J00106
[Journal Article] Use of Diffusion‐Weighted Imaging‐Alberta Stroke Program Early Computed Tomography Score (DWI‐ASPECTS) and Ischemic Core Volume to Determine the Malignant Profile in Acute Stroke2019
- Author(s)
  Yoshimoto Takeshi、Inoue Manabu、Yamagami Hiroshi、Fujita Kyohei、Tanaka Kanta、Ando Daisuke、Sonoda Kazutaka、Kamogawa Naruhiko、Koga Masatoshi、Ihara Masafumi、Toyoda Kazunori
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 8 Issue: 22
- DOI
  10.1161/jaha.119.012558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-17K00426
[Journal Article] Pleiotropic neuroprotective effects of taxifolin in cerebral amyloid angiopathy2019
- Author(s)
  Inoue Takayuki、Saito Satoshi、Tanaka Masashi、Yamakage Hajime、Kusakabe Toru、Shimatsu Akira、Ihara Masafumi、Satoh-Asahara Noriko
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 20 Pages: 10031-10038
- DOI
  10.1073/pnas.1901659116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07905, KAKENHI-PROJECT-19K07927, KAKENHI-PROJECT-18K19769, KAKENHI-PROJECT-18H02737, KAKENHI-PROJECT-19J00106
[Journal Article] Detrimental Effect of Chronic Hypertension on Leptomeningeal Collateral Flow in Acute Ischemic Stroke2019
- Author(s)
  Fujita Kyohei、Tanaka Kanta、Yamagami Hiroshi、Ide Toshihiro、Ishiyama Hiroyuki、Sonoda Kazutaka、Satow Tetsu、Takahashi Jun C.、Ihara Masafumi、Koga Masatoshi、Yokota Takanori、Toyoda Kazunori
- Journal Title
  
  Stroke
  
  Volume: 50 Issue: 7 Pages: 1751-1757
- DOI
  10.1161/strokeaha.119.025142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Effect of fingolimod on oligodendrocyte maturation under prolonged cerebral hypoperfusion2019
- Author(s)
  Yasuda Ken、Maki Takakuni、Saito Satoshi、Yamamoto Yumi、Kinoshita Hisanori、Choi Yoon Kyung、Arumugam Thiruma Valavan、Lim Yun-An、Chen Christopher Li Hsian、Wong Peter Tsun-Hon、Ihara Masafumi、Takahashi Ryosuke
- Journal Title
  
  Brain Research
  
  Volume: 1720 Pages: 146294-146294
- DOI
  10.1016/j.brainres.2019.06.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-19J00106
[Journal Article] Detection of Stenosis Progression in Intracranial Vertebral Artery Dissection Using Carotid Ultrasonography2019
- Author(s)
  Wada Shinichi、Koga Masatoshi、Makita Naoki、Nakamura Yuki、Miwa Kaori、Ide Toshihiro、Yi Kenichiro、Mizoguchi Tadataka、Yamaguchi Yoshitaka、Ihara Masafumi、Toyoda Kazunori
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 28 Issue: 8 Pages: 2201-2206
- DOI
  10.1016/j.jstrokecerebrovasdis.2019.04.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670, KAKENHI-PROJECT-16K09485
[Journal Article] アフリカでの脳卒中低減を目指した医科―歯科国際連携の試み2019
- Author(s)
  1.殿村修一，井上学，角田良介，野村良太，仲野和彦，猪原匡史
- Journal Title
  
  脳卒中
  
  Volume: 印刷中
- NAID
  130007815617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Prevalence of RNF213 p.R4810K Variant in Early-Onset Stroke With Intracranial Arterial Stenosis2019
- Author(s)
  Kamimura Teppei、Okazaki Shuhei、Morimoto Takaaki、Kobayashi Hatasu、Harada Kouji、Tomita Tsutomu、Higashiyama Aya、Yoshimoto Takeshi、Takahashi Jun C.、Nakagawara Jyoji、Koga Masatoshi、Toyoda Kazunori、Maruyama Hirofumi、Koizumi Akio、Ihara Masafumi
- Journal Title
  
  Stroke
  
  Volume: 50 Issue: 6 Pages: 1561-1563
- DOI
  10.1161/strokeaha.118.024712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06922, KAKENHI-PROJECT-19K10608, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-17H04670
[Journal Article] Significance of Nonfocal Symptoms in Patients With Transient Ischemic Attack2018
- Author(s)
  Ishihara Toshiya、Sato Shoichiro、Uehara Toshiyuki、..., Toyoda Kazunori、Minematsu Kazuo
- Journal Title
  
  Stroke
  
  Volume: 49 Issue: 8 Pages: 1893-1898
- DOI
  10.1161/strokeaha.118.022009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04308
[Journal Article] Collagen-binding Streptococcus mutans tied to cerebral microbleeds and intracerebral hemorrhage2018
- Author(s)
  Ihara Masafumi、Tonomura Shuichi、Yamamoto Yumi、Saito Satoshi
- Journal Title
  
  Future Neurology
  
  Volume: 13 Issue: 4 Pages: 219-224
- DOI
  10.2217/fnl-2018-0016
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Seasonal Variations in Neurological Severity and Outcomes of Ischemic Stroke　― 5-Year Single-Center Observational Study ―2018
- Author(s)
  Toyoda Kazunori、Koga Masatoshi、Yamagami Hiroshi、Yokota Chiaki、Sato Shoichiro、Inoue Manabu、Tanaka Tomotaka、Endo Kaoru、Fujinami Jun、Ihara Masafumi、Nagatsuka Kazuyuki、Minematsu Kazuo
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 5 Pages: 1443-1450
- DOI
  10.1253/circj.CJ-17-1310
- NAID
  130006725986
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04308
[Journal Article] Anti-Xa Activity and Event Risk in Patients With Direct Factor Xa Inhibitors Initiated Early After Stroke2018
- Author(s)
  Wada Shinichi、Toyoda Kazunori、Sato Shoichiro、Matsuki Takayuki、Okata Takuya、Kumamoto Masaya、Tagawa Naoki、Inoue Manabu、Okamoto Akira、Ihara Masafumi、Kitazono Takanari、Miyata Toshiyuki、Koga Masatoshi
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 11 Pages: 2872-2879
- DOI
  10.1253/circj.CJ-18-0506
- NAID
  40021697278
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2018-10-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04308, KAKENHI-PROJECT-16K09834
[Journal Article] Dysregulation of RNF213 promotes cerebral hypoperfusion2018
- Author(s)
  Morimoto T, Enmi J, Hattori Y, Iguchi S, Saito S, Harada K, Okuda H, Mineharu Y, Takagi Y, Youssefian S, Iida H, Miyamoto S, Ihara M, Kobayashi H, Koizumi A.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 3607-3607
- DOI
  10.1038/s41598-018-22064-8
- NAID
  120006510289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-15K19243, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-15K19963
[Journal Article] Outcome Prediction in Acute Stroke Patients by Continuous Glucose Monitoring2018
- Author(s)
  Wada Shinichi、Yoshimura Sohei、Inoue Manabu、Matsuki Takayuki、Arihiro Shoji、Koga Masatoshi、Kitazono Takanari、Makino Hisashi、Hosoda Kiminori、Ihara Masafumi、Toyoda Kazunori
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 7 Issue: 8
- DOI
  10.1161/jaha.118.008744
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04308
[Journal Article] Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia2017
- Author(s)
  Duncombe Jessica、Kitamura Akihiro、Hase Yoshiki、Ihara Masafumi、Kalaria Raj?N.、Horsburgh Karen
- Journal Title
  
  Clinical Science
  
  Volume: 131 Issue: 19 Pages: 2451-2468
- DOI
  10.1042/cs20160727
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14573
[Journal Article] Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy2017
- Author(s)
  Satoshi Saito, Yumi Yamamoto, Takakuni Maki, Yorito Hattori, Hideki Ito, Katsuhiko Mizuno, Mariko Harada-Shiba, Raj N. Kalaria, Masanori Fukushima, Ryosuke Takahashi, Masafumi Ihara
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 5 Issue: 1 Pages: 26-26
- DOI
  10.1186/s40478-017-0429-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14958, KAKENHI-PROJECT-15H04271
[Journal Article] Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion2017
- Author(s)
  Kitamura Akihiro、Manso Yasmina、Duncombe Jessica、Searcy James、Koudelka Juraj、Binnie Margaret、Webster Scott、Lennen Ross、Jansen Maurits、Marshall Ian、Ihara Masafumi、Kalaria Raj N.、Horsburgh Karen
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 4299-4299
- DOI
  10.1038/s41598-017-04082-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271
[Journal Article] Swallowing-induced displacement of the carotid artery as a risk of stroke: Flip-flop phenomenon2017
- Author(s)
  Kinoshita Naoto、Saito Kozue、Tanaka Tomotaka、Kajimoto Katsufumi、Yamagami Hiroshi、Morita Yoshiaki、Ihara Masafumi、Nagatsuka Kazuyuki
- Journal Title
  
  Neurology
  
  Volume: 89 Issue: 15 Pages: 1643-1644
- DOI
  10.1212/wnl.0000000000004492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04271
[Journal Article] Medial temporal lobe atrophy is the norm in cerebrovascular dementias2017
- Author(s)
  Kalaria R. N.、Ihara M.
- Journal Title
  
  European Journal of Neurology
  
  Volume: 24 Issue: 4 Pages: 539-540
- DOI
  10.1111/ene.13243
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Journal Article] Frontal White Matter Hyperintensities, Clasmatodendrosis and Gliovascular Abnormalities in Ageing and Post-stroke Dementia2016
- Author(s)
  13.Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung’u MN, Foster V, Craggs LJL, Washida K, Okamoto Y, Thomas AJ, Polvikosk TM, Allan JM, Oakley AE, O’Brien JT, Horsburgh K, Ihara M, Kalaria RN
- Journal Title
  
  Brain
  
  Volume: 139 Issue: 1 Pages: 242-258
- DOI
  10.1093/brain/awv328
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271
[Journal Article] Hemisphere asymmetry of response to treatment in an Alzheimer’s disease mouse model2016
- Author(s)
  Manousopoulou A, Saito S, Yamamoto Y, Al-Daghri NM, Ihara M, Carare RO, Garbis SD
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 21 Issue: 2 Pages: 333-338
- DOI
  10.3233/jad-151078
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
[Journal Article] Imaging of Cerebral Amyloid Angiopathy with Bivalent 99mTc-Hydroxamamide Complexes2016
- Author(s)
  Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Hiroyuki Kimura, Hatsue Ishibashi-Ueda, Yoko Okamoto, Masafumi Ihara, Hideo Saji.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 25990-25990
- DOI
  10.1038/srep25990
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J05493, KAKENHI-PROJECT-26293274
[Journal Article] Interaction between cerebrovascular disease and Alzheimer pathology2016
- Author(s)
  Saito S, Ihara M
- Journal Title
  
  Curr Opin Psychiatry
  
  Volume: 29 Issue: 2 Pages: 168-173
- DOI
  10.1097/yco.0000000000000239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
[Journal Article] Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory2016
- Author(s)
  Kitamura A, Saito S, Maki A, Ayaki T, Oishi N, Kalaria RN, Hattori Y, Yamamoto Y, Urushitani M, Horsburgh K, Fukuyama H, Takahashi R, Ihara M
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: - Issue: 9 Pages: 1592-1602
- DOI
  10.1177/0271678x15606717
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26290023, KAKENHI-PROJECT-15K09920
[Journal Article] Novel Bivalent 99mTc-Complex with N-Methyl-Substituted Hydroxamamide as Probe for Imaging of Cerebral Amyloid Angiopathy2016
- Author(s)
  Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Masashi Yoshimura, Hatsue Ishibashi-Ueda, Masafumi Ihara, Hideo Saji.
- Journal Title
  
  PLoS One
  
  Volume: 11(9) Issue: 9 Pages: e0163969-e0163969
- DOI
  10.1371/journal.pone.0163969
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J05493, KAKENHI-PROJECT-26293274
[Journal Article] う蝕原因菌と脳出血の関連－脳口連関－．2016
- Author(s)
  殿村修一，仲野和彦，猪原匡史
- Journal Title
  
  日本歯科論評
  
  Volume: 76 Pages: 14-15
- Data Source
  KAKENHI-PROJECT-16K14573
[Journal Article] Gradual Carotid Artery Stenosis in Mice Closely Replicates Hypoperfusive Vascular Dementia in Humans.2016
- Author(s)
  Hattori Y, Enmi J, Iguchi S, Saito S, Yamamoto Y, Tsuji M, Nagatsuka K, Kalaria RN, Iida H, Ihara M
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 5 Issue: 2
- DOI
  10.1161/jaha.115.002757
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461867, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26640034
[Journal Article] Emerging evidence for pathogenesis of sporadic cerebral small vessel disease2016
- Author(s)
  Ihara M, Yamamoto Y
- Journal Title
  
  Stroke
  
  Volume: 47 Issue: 2 Pages: 554-560
- DOI
  10.1161/strokeaha.115.009627
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-16K18387
[Journal Article] Influence of low-dose aspirin on cerebral amyloid angiopathy in mice2016
- Author(s)
  Hattori Y, Maki T, Saito S, Yamamoto Y, Nagatsuka K, Ihara M
- Journal Title
  
  J Alzheimers Dis
  
  Volume: - Issue: 3 Pages: 1037-1045
- DOI
  10.3233/jad-160013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04271
[Journal Article] Oral Cnm-positive Streptococcus Mutans Expressing Collagen Binding Activity is a Risk Factor for Cerebral Microbleeds and Cognitive Impairment.2016
- Author(s)
  Watanabe I, Kuriyama N, Miyatani F, Nomura R, Naka S, Nakano K, Ihara M, Iwai K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Tamura A, Mizuno T, Akazawa K6, Takada A, Takeda K, Yamada K, Nakagawa M, Tanaka T, Kanamura N, Friedland RP, Watanabe Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 1-5
- DOI
  10.1038/srep38561
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10318, KAKENHI-PROJECT-16K14573, KAKENHI-PROJECT-16H06277
[Journal Article] Stroke Injury, cognitive Impairment and vascular dementia2016
- Author(s)
  Kalaria RN, Akinyemi R, Ihara M
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: - Issue: 5 Pages: 915-925
- DOI
  10.1016/j.bbadis.2016.01.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271
[Journal Article] Structure-Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents that Selectively Detect Neurofibrillary Tangles in Alzheimer’s Disease Brains2015
- Author(s)
  Matsumura K, Ono M, Kitada A, Watanabe H, Yoshimura M, Iikuni S, Kimura H, Okamoto Y, Ihara M, Saji H.
- Journal Title
  
  J Med Chem
  
  Volume: 58 Issue: 18 Pages: 7241-7257
- DOI
  10.1021/acs.jmedchem.5b00440
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01555, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-14J05961
[Journal Article] Immunolocalisation of PDGFRβ and pericytes in CADASIL2015
- Author(s)
  Craggs LJL, Fenwick R, Oakley AE, Ihara M, Kalaria RN
- Journal Title
  
  Neuropath Appl Neurobiol
  
  Volume: 41 Issue: 4 Pages: 557-570
- DOI
  10.1111/nan.12188
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271
[Journal Article] SIRT1 attenuates severe ischemic damage by preserving cerebral blood flow.2015
- Author(s)
  Hattori Y, Okamoto Y, Nagatsuka K, Takahashi R, Kalaria RN, Kinoshita M, Ihara M
- Journal Title
  
  NeuroReport
  
  Volume: 26 Issue: 3 Pages: 113-117
- DOI
  10.1097/wnr.0000000000000308
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26640034, KAKENHI-PLANNED-23111002
[Journal Article] Mild cognitive impairment: at the crossroad of neurodegeneration and vascular dysfunction2015
- Author(s)
  Saito S, Yamamoto Y, Ihara M
- Journal Title
  
  Curr Alzheimer Res
  
  Volume: 12 Issue: 6 Pages: 507-512
- DOI
  10.2174/1567205012666150530202508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26893337
[Journal Article] A novel mouse model of subcortical infarcts with dementia.2015
- Author(s)
  Hattori Y, Enmi J, Kitamura A, Yamamoto Y, Saito S, Takahashi Y, Iguchi S, Tsuji M, Yamahara K, Nagatsuka K, Iida H, Ihara M
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 35 Issue: 9 Pages: 3915-3928
- DOI
  10.1523/jneurosci.3970-14.2015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461867, KAKENHI-PROJECT-25640031
[Journal Article] microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.2015
- Author(s)
  Kim J, Yoon H, Horie T, Burchett JM, Restivo JL, Rotllan N, Ramírez CM, Verghese PB, Ihara M, Hoe HS, Esau C, Fernández-Hernando C, Holtzman DM, Cirrito JR, Ono K, Kim J.
- Journal Title
  
  J Neurosci.
  
  Volume: 35(44) Issue: 44 Pages: 14717-26
- DOI
  10.1523/jneurosci.2053-15.2015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26293186
[Journal Article] Translation of pre-clinical studies into successful clinical trials for Alzheimer’s disease: what are the roadblocks and how can they be overcome?2015
- Author(s)
  Banik A, Brown RE, Bamburg J, Lahiri DK, Khurana D, Friedland RP, Chen W, Ding Y, Mudher A, Padjen AL, Mukaetova-Ladinska E, Ihara M, Srivastava E, Srivastava MVP, Masters CL, Kalaria RN, Anand A
- Journal Title
  
  J Alzheimer Dis
  
  Volume: 47 Issue: 4 Pages: 815-843
- DOI
  10.3233/jad-150136
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271
[Journal Article] 注目される脳小血管病による認知症．2014
- Author(s)
  猪原匡史
- Journal Title
  
  Dementia Japan
  
  Volume: 28 Pages: 57-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640031
[Journal Article] Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid.2014
- Author(s)
  Maki T, Okamoto Y, Carare RO, Hase Y, Hattori Y, Hawkes CA, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda H, Taguchi A, Takahashi R, Miyakawa T, Kalaria RN, Lo EH, Arai K, Ihara M
- Journal Title
  
  Ann Clin Transl Neurol
  
  Volume: 1 Issue: 8 Pages: 519-533
- DOI
  10.1002/acn3.79
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25640031
[Journal Article] Cilostazol add-on therapy in patients with mild dementia receiving donepezil : a retrospective study2014
- Author(s)
  Ihara M, Nishino M, Taguchi A, Yamamoto Y, Hattori Y, Saito S, Takahashi Y, Tsuji M, Kasahara Y, Takata Y, Okada M
- Journal Title
  
  PloS ONE
  
  Volume: 9(2) Issue: 2 Pages: e89516-e89516
- DOI
  10.1371/journal.pone.0089516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] 注目される脳小血管病による認知症．2014
- Author(s)
  猪原匡史
- Journal Title
  
  Dementia Japan
  
  Volume: 28 Pages: 57-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233
[Journal Article] Effects of intravenous administration of umbilical cord blood CD34+ cells in a mouse model of neonatal stroke.2014
- Author(s)
  Tsuji M, Taguchi A, Ohshima M, Kasahara Y, Sato Y, Tsuda H, Otani K, Yamahara K, Ihara M, Harada-Shiba M, Ikeda T, Matsuyama T.
- Journal Title
  
  Neuroscience
  
  Volume: 263 Pages: 148-158
- DOI
  10.1016/j.neuroscience.2014.01.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23500448, KAKENHI-PROJECT-23791220, KAKENHI-PROJECT-24591617, KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26461630
[Journal Article] Silent Information Regulator 2 Homolog 1 Counters Cerebral Hypoperfusion Injury by Deacetylating Endothelial Nitric Oxide Synthase2014
- Author(s)
  Hattori Y, Okamoto Y, Maki T, Yamamoto Y, Oishi N, Yamahara K, Nagatsuka K, Takahashi R, Kalaria RN, Fukuyama H, Kinoshita M, Ihara M
- Journal Title
  
  Stroke
  
  Volume: 45 Issue: 11 Pages: 3403-3411
- DOI
  10.1161/strokeaha.114.006265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390292, KAKENHI-PROJECT-24791296, KAKENHI-PROJECT-25640031, KAKENHI-PROJECT-26640034, KAKENHI-PROJECT-22220003
[Journal Article] 注目される脳小血管病による認知症2014
- Author(s)
  猪原匡史
- Journal Title
  
  Dementia Japan
  
  Volume: 28(1) Pages: 57-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233
[Journal Article] 高血糖とアルツハイマー病．2014
- Author(s)
  猪原匡史
- Journal Title
  
  医学のあゆみ
  
  Volume: 249 Pages: 545-550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233
[Journal Article] A mouse model of chronic cerebral hypoperfusion characterizing features of cognitive impairment2014
- Author(s)
  Ihara M, Taguchi A, Maki T, Washida K, Tomimoto H
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1135 Pages: 95-102
- DOI
  10.1007/978-1-4939-0320-7_8
- ISBN
  9781493903191, 9781493903207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] Motor and cognitive impairment in a mouse model of ischemic carotid artery disease.2014
- Author(s)
  Hattori Y, Kitamura A, Tsuji M, Nagatsuka K, Ihara M
- Journal Title
  
  Neurosci Lett
  
  Volume: 581 Pages: 1-6
- DOI
  10.1016/j.neulet.2014.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640031
[Journal Article] 高血糖とアルツハイマー病．2014
- Author(s)
  猪原匡史
- Journal Title
  
  医学のあゆみ
  
  Volume: 249 Pages: 545-550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640031
[Journal Article] Greater suitability of the Montreal Cognitive Assessment against the Mini-Mental State Examination in the detection of vascular cognitive impairment2013
- Author(s)
  Ihara M, Okamoto Y, Takahashi R
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 22(6) Issue: 6 Pages: 737-41
- DOI
  10.1016/j.jstrokecerebrovasdis.2012.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182, KAKENHI-PROJECT-25640031
[Journal Article] An highly reproducible model of cerebralischemia/reperfusion with extended survival in CB-17 mice2013
- Author(s)
  Kasahara Y, Ihara M, Nakagomi T, Momota Y, Sterm D, Matsuyama T, Taguchi A
- Journal Title
  
  Neurosci Res
  
  Volume: 76 Issue: 3 Pages: 163-168
- DOI
  10.1016/j.neures.2013.04.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592271, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23500448, KAKENHI-PROJECT-25463159, KAKENHI-PROJECT-25640031
[Journal Article] Structure-activity Relationships and in vivo Evaluation of Quinoxaline Derivatives for PET Imaging of β-Amyloid Plaques.2013
- Author(s)
  Yoshimura M, Ono M, Matsumura K, Watanabe H, Kimura H, Cui M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H.
- Journal Title
  
  ACS Med Chem Lett
  
  Volume: 4 Issue: 7 Pages: 596-600
- DOI
  10.1021/ml4000707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] Vascular and neurodegenerative pathways-will they meet?2013
- Author(s)
  Kalaria RN, Ihara M
- Journal Title
  
  Nat Rev Neurol
  
  Volume: 9(9) Issue: 9 Pages: 487-488
- DOI
  10.1038/nrneurol.2013.164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] Synthesis and biological evaluation of novel styryl benzimidazole derivatives as probes for imaging of neurofibrillary tangles in Alzheimer's disease.2013
- Author(s)
  Matsumura K, Ono M, Yoshimura M, Kimura H, Watanabe H, Okamoto Y, Ihara M, Takahashi R, Saji H.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 21 Issue: 11 Pages: 3356-3362
- DOI
  10.1016/j.bmc.2013.02.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-24659564, KAKENHI-PROJECT-25640031
[Journal Article] 認知症の診断と治療を目指した小血管病の管理2013
- Author(s)
  猪原匡史
- Journal Title
  
  Brain and Nerve
  
  Volume: 65(7) Pages: 801-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233
[Journal Article] 認知症の診断と治療を目指した小血管病の管理2013
- Author(s)
  猪原匡史
- Journal Title
  
  Brain and Nerve
  
  Volume: 65 Pages: 801-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640031
[Journal Article] Visualization of Lenticulostriate Arteries by Flow-Sensitive Black-Blood MR Angiography on a 1.5T MRI System: A Comparative Study between Subjects with and without Stroke. AJNR Am J Neuroradiol.2013
- Author(s)
  Okuchi S
- Journal Title
  
  AJNR Am J Neuroradiol
  
  Volume: 34 Issue: 4 Pages: 780-784
- DOI
  10.3174/ajnr.a3310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-24591757, KAKENHI-PROJECT-25640031, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002
[Journal Article] Association of Physical Activity with the Visuospatial/Executive Functions of the Montreal Cognitive Assessment in Patients with Vascular Cognitive Impairment2013
- Author(s)
  Ihara M, Okamoto Y, Hase Y, Takahashi R
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 22(7) Issue: 7 Pages: 339-4
- DOI
  10.1016/j.jstrokecerebrovasdis.2012.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] Experimental and clinical challenge for neuroregeneration following stroke.2013
- Author(s)
  Kasahara Y, Ihara M, Taguchi A.
- Journal Title
  
  Front Neurol Neurosci
  
  Volume: 32 Pages: 69-75
- DOI
  10.1159/000346416
- ISBN
  9783318023084, 9783318023091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] White matter pathology and disconnection in the frontal lobe in CADASIL2013
- Author(s)
  Craggs LJL, Yamamoto Y, et al.
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: (Epub ahead of orint) Issue: 5 Pages: 591-602
- DOI
  10.1111/nan.12073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07954, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] 認知症における血管病の重要性2013
- Author(s)
  猪原匡史
- Journal Title
  
  脳循環代謝
  
  Volume: 24(2) Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233
[Journal Article] 認知症における血管病の重要性．2013
- Author(s)
  猪原匡史
- Journal Title
  
  脳循環代謝
  
  Volume: 24 Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233
[Journal Article] Cilostazol improves cognitive function in patients with mild cognitive impairment : A retrospective analysis2013
- Author(s)
  Taguchi A, Takata Y, Ihara M, Kasahara Y, Tsuji M, Nishino M, Stern D, Okada M
- Journal Title
  
  Psychogeriatrics
  
  Volume: 13(3) Issue: 3 Pages: 164-169
- DOI
  10.1111/psyg.12021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] Vascular Risk Factors and Neurodegeneration in Ageing related Dementias : Alzheimer' s Disease and Vascular Dementia2013
- Author(s)
  Akinyemi R, Mukaetova-Ladinska E, Attems J, Ihara M, Kalaria RN
- Journal Title
  
  Curr Alzheimer Res
  
  Volume: 10(6) Issue: 6 Pages: 642-53
- DOI
  10.2174/15672050113109990037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] 認知症における血管病の重要性．2013
- Author(s)
  猪原匡史
- Journal Title
  
  脳循環代謝
  
  Volume: 24 Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640031
[Journal Article] Development of Novel (123)I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer's Disease.2013
- Author(s)
  Ono M, Cheng Y, Kimura H, Watanabe H, Matsumura K, Yoshimura M, Iikuni S, Okamoto Y, Ihara M, Takahashi R, Saji H.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 9 Pages: e74104-e74104
- DOI
  10.1371/journal.pone.0074104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-25640031
[Journal Article] 18F-labeled Phenyldiazenyl Benzothiazole for invivo Imaging of Neurofibrillary Tangles in Alzheimer's Disease Brains2012
- Author(s)
  Matsumura K, Ono M, Kimura H, Ueda M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H
- Journal Title
  
  ACS Med Chem Lett
  
  Volume: 3(1) Issue: 1 Pages: 58-62
- DOI
  10.1021/ml200230e
- Data Source
  KAKENHI-PROJECT-23650182
[Journal Article] Environmental enrichment ameliorated high fat diet-induced Aβdeposition and memory deficit in APP transgenic mice2012
- Author(s)
  Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Asada M, Watanabe K, Hayashida N, Ihara M, Ito H, ShimohamaS, Kihara T, Kinoshita A
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 33 Issue: 5 Pages: 11-23
- DOI
  10.1016/j.neurobiolaging.2011.10.028
- NAID
  120003988394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23591243, KAKENHI-PROJECT-23650182, KAKENHI-PUBLICLY-24111524
[Journal Article] Cerebral hypoperfusion induces microinfarcts in cerebral amyloid angiopathy2012
- Author(s)
  Okamoto Y, Yamamoto T, Kalaria RN, Senzaki H, Maki T, Hase Y, Kitamura A, Washida K, Yamada M, Ito H, Tomimoto H, Takahashi R, Ihara M
- Journal Title
  
  Acta Neuropathol
  
  Volume: 123(3) Issue: 3 Pages: 381-394
- DOI
  10.1007/s00401-011-0925-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Cilostazol, a phosphodiesterase inhibitor, prevents no-reflow and hemorrhage in mice with focal cerebral ischemia2012
- Author(s)
  Hase Y, Okamoto Y, Fujita Y, KitamuraA, Ito H, Maki T, Washida K, TakahashiR, Ihara M
- Journal Title
  
  Experimental Neurology
  
  Volume: 233 Issue: 1 Pages: 523-533
- DOI
  10.1016/j.expneurol.2011.11.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Selective white matter abnormalities in a novel rat model of vascular dementia2012
- Author(s)
  Kitamura A, Fujita Y, Oishi N, KalariaR N, Washida K, Maki T, Okamoto Y, HaseY, Yamada M, Takahashi J, Ito H, Tomimoto H, Fukuyama H, Takahashi R, Ihara M
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 33 Issue: 5 Pages: 25-35
- DOI
  10.1016/j.neurobiolaging.2011.10.033
- NAID
  120003988349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22220003, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Phenyldiazenyl benzothiazole derivatives as probes for in vivo imaging of neurofibrillary tangles in Alzheimer's disease brains2011
- Author(s)
  Matsumura K, Ono M, et al
- Journal Title
  
  Med Chem Comm
  
  Volume: 2 Issue: 7 Pages: 596-600
- DOI
  10.1039/c1md00034a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Selective white matter pathology induces a specific impainnent in spatial working memory2011
- Author(s)
  Coltman R, Spain A, et al
- Journal Title
  
  Neurobiol Aging
  
  Volume: 32 Issue: 12 Pages: 2324.e7-2324.e12
- DOI
  10.1016/j.neurobiolaging.2010.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Angiogenic roles of adreno medullin through VEGF induction2011
- Author(s)
  Maki T, Ihara M, Fujita Y, Nambu T, Harada H, Ito H, Nakao K, Tomimoto H, Takahashi R
- Journal Title
  
  Neuroreport
  
  Volume: 22 Issue: 9 Pages: 442-447
- DOI
  10.1097/wnr.0b013e32834757e4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice.2011
- Author(s)
  Maki T, Ihara M, et al.
- Journal Title
  
  Stroke
  
  Volume: 42 Pages: 1125-1131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] Watershed Infarcts in a multiple microembolic model of monkey2011
- Author(s)
  Maki T, Wakita H, Mase M, Itagaki I, Saito N, Ono F, Adachi K, Ito H, Takahashi R, Ihara M, Tomimoto H
- Journal Title
  
  Neuroscience Letters
  
  Volume: 499 Issue: 2 Pages: 80-83
- DOI
  10.1016/j.neulet.2011.05.036
- NAID
  120003238944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-21591106, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011
- Author(s)
  Tomimoto H
- Journal Title
  
  Stroke
  
  Volume: 42(4) Issue: 4 Pages: 1122-8
- DOI
  10.1161/strokeaha.110.603399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21256005, KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains2011
- Author(s)
  Ono M, Hayashi S, et al
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 2 Issue: 5 Pages: 269-275
- DOI
  10.1021/cn200002t
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] The influence of chronic cerebral hypoperfusion on cognitive function and amyloid b metabolism in APP overexpressing mice2011
- Author(s)
  Yamada M, Ihara M, Okamoto Y, Maki T, Washida K, Kitamura A, Hase Y, Ito H, Takao K, Miyakawa T, Kalaria RN, Tomimoto H, Takahashi R
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 1 Pages: e16567-e16567
- DOI
  10.1371/journal.pone.0016567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-23390233
[Journal Article] Co localization of 14-3-3 proteins with SOD1 in Lewy Body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model2011
- Author(s)
  Okamoto Y, Shirakashi Y, Ihara M, Urushitani M, Oono M, Kawamoto Y, Yamashita H, Shimohama S, Kato S, Hirano A, Tomimoto H, Ito H, Takahashi R
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 5 Pages: e20427-e20427
- DOI
  10.1371/journal.pone.0020427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930, KAKENHI-PROJECT-22659171, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation2011
- Author(s)
  Ito H, Nakamura M, Komure O, Ayaki T, Wate R, Maruyama H, Nakamura Y, FujitaK, Kaneko S, Okamoto Y, Ihara M, Konishi T, Ogasawara K, Hirano A, Kusaka H, KajiR, Takahashi R, Kawakami H
- Journal Title
  
  Acta Neuropathologica
  
  Volume: 122 Issue: 2 Pages: 223-229
- DOI
  10.1007/s00401-011-0842-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-22590930, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23591246, KAKENHI-PROJECT-23650182
[Journal Article] Lessons from a mouse model characterizing features of vascular cognitive impairment with white matter changes2011
- Author(s)
  Ihara M, Tomimoto H
- Journal Title
  
  J Aging Res
  
  Volume: 2011 Pages: 978761-978761
- DOI
  10.4061/2011/978761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] The influence of chronic cerebral hypoperfusion on cognitive function and amyloid β metabolism in APP overexpressing mice.2011
- Author(s)
  Yamada M, Ihara M, et.al.
- Journal Title
  
  PLoS One
  
  Volume: 6
- NAID
  120002871155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] An autopsy case of SOD1-related ALS with TDP-43 positive inclusions2011
- Author(s)
  Okamoto Y, Ihara M, Urushitani M, Yamashita H, Kondo T, Tanigaki A, Oono M, Kawamata J, Ikemoto A, Kawamoto Y, Takahashi R, Ito H
- Journal Title
  
  Neurology
  
  Volume: 77:1993-1995 Issue: 22 Pages: 1993-1995
- DOI
  10.1212/wnl.0b013e31823a0cfc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590930, KAKENHI-PROJECT-22659171, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-23300131, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
[Journal Article] A mouse model characterizing features of vascular dementia with hippocampal atrophy.2010
- Author(s)
  Nishio K, Ihara M, et al.
- Journal Title
  
  Stroke
  
  Volume: 41 Pages: 1278-1284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies.2010
- Author(s)
  Ihara M, Plvikoski TM, et al.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 119 Pages: 579-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] 亜急性に進行する発動性低下のみを呈した内包膝部branch atheromatous diseaseの一例2010
- Author(s)
  北村彰浩, 猪原匡史, ら
- Journal Title
  
  脳卒中
  
  Volume: 32 Pages: 384-389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] 脳血管障害による認知機能障害;Vascular cognitive impairment2010
- Author(s)
  猪原匡史
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 22 Pages: 53-59
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] 脳血管障害に基づく認知機能障害の病態2010
- Author(s)
  猪原匡史, 岡本洋子, ら
- Journal Title
  
  脳卒中
  
  Volume: 32 Pages: 614-620
- NAID
  10027895761
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] Early protective effect of bone marrow mononuclear cells against ischemic white matter damage through augmentation of cerebral blood flow.2010
- Author(s)
  Fujita Y, Ihara M, et al.
- Journal Title
  
  Stroke
  
  Volume: 41 Pages: 2938-2943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to PPAR-γ activation in mice with chronic cerebral hypoperfusion.2010
- Author(s)
  Washida K, Ihara M, et al.
- Journal Title
  
  Stroke
  
  Volume: 41 Pages: 1798-1806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650073
[Journal Article] Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β -amyloid
- Author(s)
  Maki T, Okamoto Y, Carare R, Hase Y, Hattori Y, Hawkes C, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda, H, Taguchi A, Takahashi R, Miyakawa T, Kalaria R, Lo E, Arai K, Ihara M
- Journal Title
  
  Ann Clin Transl Neurol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233
[Journal Article] 高血糖とアルツハイマー病
- Author(s)
  猪原匡史
- Journal Title
  
  医学のあゆみ
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390233
[Patent] 被験者の脳微小出血の重症化リスクを予測する方法、脳微小出血の重症化リスクの高い被験者をスクリーニングする方法、及びそれらに用いるキット2020
- Inventor(s)
  猪原匡史，齊藤聡，服部頼都，湯原悟志，西脇森衛
- Industrial Property Rights Holder
  猪原匡史，齊藤聡，服部頼都，湯原悟志，西脇森衛
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K22610
[Patent] タキシフォリンを含有する肝線維化抑制剤及び褐色脂肪細胞活性化剤2019
- Inventor(s)
  浅原哲子、井上隆之、田中将志、猪原匡史、齊藤聡
- Industrial Property Rights Holder
  独立行政法人国立病院機構、他3者
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-011729
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02737
[Patent] 認知症の予防及び／又は治療のための薬剤2016
- Inventor(s)
  猪原匡史，齊藤聡，松本忠冒, 福島雅典
- Industrial Property Rights Holder
  猪原匡史，齊藤聡，松本忠冒, 福島雅典
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15H04271
[Patent] 放射性ハロゲン標識ピリド[1,2-a]ベンゾイミダゾール誘導体化合物2015
- Inventor(s)
  小野正博、佐治英郎、猪原匡史、松本博樹、関育也
- Industrial Property Rights Holder
  小野正博、佐治英郎、猪原匡史、松本博樹、関育也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-161472
- Filing Date
  2015-08-19
- Data Source
  KAKENHI-PROJECT-15H04271
[Patent] 間質流改善薬2012
- Inventor(s)
  猪原匡史, 眞木崇州, 田口明彦
- Industrial Property Rights Holder
  公益財団法人・先端医療振興財団
- Industrial Property Number
  2012-135906
- Filing Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-23390233
[Patent] 間質流改善薬2012
- Inventor(s)
  猪原匡史、眞木崇州、田口明彦
- Industrial Property Rights Holder
  猪原匡史、眞木崇州、田口明彦
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 嫌悪画像に対する聴覚刺激の影響2022
- Author(s)
  山内美穂，岩切昌宏，権藤恭之，猪原匡史
- Organizer
  日本光脳機能イメージング学会
- Data Source
  KAKENHI-PROJECT-18K03167
[Presentation] 嫌悪画像に対する聴覚刺激の効果の検討2022
- Author(s)
  山内美穂，岩切昌宏，権藤恭之，猪原匡史
- Organizer
  日本EMDR学会第17回学術大会
- Data Source
  KAKENHI-PROJECT-18K03167
[Presentation] 嫌悪画像に対する聴覚刺激の効果の検討2022
- Author(s)
  山内美穂，岩切昌宏，権藤恭之，猪原匡史
- Organizer
  日本EMDR学会第17回学術大会
- Data Source
  KAKENHI-PROJECT-22K03166
[Presentation] RNF213 p.R4810K多型は頭蓋内動脈狭窄症の進行を予測する:15年長期追跡研究の成果2022
- Author(s)
  岡﨑周平, 吉本武史, 渡辺光太郎, 大原真理子, 権泰史, 藤堂謙一, 佐々木勉, 猪原匡史, 望月秀樹
- Organizer
  第47回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06922
[Presentation] Bilateral alternating stimulation of sound reduce recall contents2021
- Author(s)
  Yamauchi M, Iida H, Nakagawara J, Ihara M.
- Organizer
  EMDR Europe Research & Practice Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K03167
[Presentation] 脳内出血発症における齲蝕原性細菌の病的意義2021
- Author(s)
  猪原匡史
- Organizer
  日本脳卒中学会
- Data Source
  KAKENHI-PROJECT-19K22610
[Presentation] 急性期被殻出血における摂食嚥下予後予測スコア2021
- Author(s)
  福間一樹, 田中智貴, 千葉哲矢, 千葉哲矢, 古賀政利, 猪原匡史
- Organizer
  第39回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20H04047
[Presentation] RNF213ｐ.R4810K遺伝子多型を有する頭蓋内動脈狭窄症患者は動脈硬化累積リスクが低い2021
- Author(s)
  大原真理子,吉本武史,岡崎周平,権泰史,藤堂謙一,佐々木勉,高杉純司,尾原信行,猪原匡史,望月秀樹
- Organizer
  第47回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06922
[Presentation] Taxifolin is a novel therapeutic agent for cerebral amyloid angiopathy2020
- Author(s)
  Satoshi Saito, Masashi Tanaka, Noriko Satoh-Asahara, Roxana O Carare1, and Masafumi Ihara
- Organizer
  121st Meeting of the British Neuropathological Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07927
[Presentation] Bilateral alternating stimulation of sound reduce recall contents2020
- Author(s)
  Yamauchi M, Iida H, Nakagawara J, Ihara M.
- Organizer
  EMDR Europe Research & Practice Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K03167
[Presentation] 頭蓋内動脈狭窄におけるRNF213 p.R4810K多型とMRI血管壁イメージングの関連2020
- Author(s)
  渡邊光太郎、岡崎周平、吉本武史、藤堂謙一、佐々木勉、古賀政利,望月秀樹、猪原匡史
- Organizer
  第45回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06922
[Presentation] PROGNOSTIC FACTORS OF SWALLOWING FUNCTION IN PATIENTS WITH PONTINE HEMORRHAGE2020
- Author(s)
  Luna Kimihira, Kazuki Fukuma, Masafumi Ihara, et al.
- Organizer
  ESO-WSO conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04047
[Presentation] Taxifolin is a novel therapeutic agent for Alzheimer’s disease and cerebral amyloid angiopathy2020
- Author(s)
  Satoshi Saito, Masashi Tanaka, Noriko Satoh-Asahara, Roxana O. Carare, Roy O. Weller, Masafumi Ihara
- Organizer
  Alzheimer's Association International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07927
[Presentation] Modeling mural cell pathology of CADASIL with disease-specific iPS cells.2020
- Author(s)
  Masafumi Ihara
- Organizer
  International Stroke Conference 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Role of induced pluripotent stem cell in CADASIL research2019
- Author(s)
  Masafumi Ihara
- Organizer
  CADASIL symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Update: treatment of small vessel disease.2019
- Author(s)
  Masafumi Ihara
- Organizer
  2019 Asia Stroke Joint Meeting (ASJM) and Stroke Treatment and Research Society-Taiwan (STARS-Taiwan) Spring Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Medical management for small vessel disease.2019
- Author(s)
  Masafumi Ihara
- Organizer
  International Stroke Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Mechanism and management of stroke-associated comorbidities, dementia and epilepsy2019
- Author(s)
  Masafumi Ihara
- Organizer
  Brain & Brain PET 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Collagen-binding Streptococcus mutans tied to intracerebral hemorrhage2019
- Author(s)
  Masafumi Ihara
- Organizer
  日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K22610
[Presentation] 虫歯・歯周病と脳卒中・認知症の関連（RAMESSES研究）2019
- Author(s)
  猪原匡史
- Organizer
  日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22610
[Presentation] Clinical trial on human lymphatic drainage system.2018
- Author(s)
  Masafumi Ihara
- Organizer
  XXI Symposium Neuroradiologicum (SNR2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Bench to bedside: using mouse models to identify new treatment approaches for dementia.2018
- Author(s)
  Masafumi Ihara
- Organizer
  CINP2018 (31st The International College of Neuropsychopharmacology)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Cerebral hypoperfusion.2018
- Author(s)
  Masafumi Ihara
- Organizer
  16th Asian Oceanian Congress of Neurology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Pathogenesis of sporadic small vessel disease.2018
- Author(s)
  Masafumi Ihara
- Organizer
  2nd Asia-Pacific Aging Protection Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] Dental microbes and stroke/dementia2017
- Author(s)
  Masafumi Ihara
- Organizer
  Brain Ageing and Dementia in LIMICS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04670
[Presentation] 慢性脳低灌流はタウ病理を加速させる: 脳血管アミロイド血管症とタウとの関連2017
- Author(s)
  齊藤聡、山本由美、高橋良輔、猪原匡史
- Organizer
  脳循環代謝学会
- Data Source
  KAKENHI-PROJECT-15H04271
[Presentation] cnm遺伝子陽性Streptococcus mutansと脳微小出血の分布との関連2017
- Author(s)
  殿村修一, 齊藤聡, 峰松一夫, 猪原匡史
- Organizer
  脳ドック学会
- Data Source
  KAKENHI-PROJECT-16K14573
[Presentation] Vascular Dementia2017
- Author(s)
  Masafumi Ihara
- Organizer
  International Stroke Conference
- Place of Presentation
  Houston, USA
- Year and Date
  2017-02-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14573
[Presentation] Dental microbes and stroke/dementia.2016
- Author(s)
  Masafumi Ihara
- Organizer
  Brain Ageing and Dementia in LIMICS 2016
- Place of Presentation
  Nairobi, Kenya
- Year and Date
  2016-12-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14573
[Presentation] 脳卒中の新たな危険因子－口腔内感染－．2016
- Author(s)
  猪原匡史
- Organizer
  日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K14573
[Presentation] Experimental evidence linking vascular factors to Alzheimer's disease2015
- Author(s)
  Masafumi Ihara
- Organizer
  Alzheimer's Association International Conference (AAIC)
- Place of Presentation
  Washington DC, USA
- Year and Date
  2015-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271
[Presentation] Animal Model of VCI2015
- Author(s)
  Masafumi Ihara
- Organizer
  Vas-Cog International
- Place of Presentation
  Tokyo
- Year and Date
  2015-09-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04271
[Presentation] Vascular Cognitive Impairment2015
- Author(s)
  猪原匡史
- Organizer
  第20回認知神経科学会
- Place of Presentation
  東京
- Year and Date
  2015-08-09
- Invited
- Data Source
  KAKENHI-PROJECT-15H04271
[Presentation] ドラッグ・リポジショニングの手法を用いた軽度認知障害に対する創薬戦略2015
- Author(s)
  猪原匡史
- Organizer
  第38回分子生物学会年会・第88回生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H04271
[Presentation] Bone morphogenetic protein‐4 expression by pericytes correlates with white matter damage in dementing disorders2015
- Author(s)
  Masafumi Ihara
- Organizer
  Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  Kobe
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H04271
[Presentation] 血管病を標的とした認知症治療2015
- Author(s)
  猪原匡史
- Organizer
  第5回認知症予防学会
- Place of Presentation
  神戸
- Year and Date
  2015-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H04271
[Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題2013
- Author(s)
  Ihara M
- Organizer
  Novel mechanism and therapy to treat patient with dementia. Neuro2013
- Place of Presentation
  京都
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Symposium S(4) -1. Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment (VCI) . Cerebral amyloid angiopathy and cognitive impairment2013
- Author(s)
  Ihara M
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2013-06-01
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Bench to bedside : using mouse models to identify new treatment approaches for Alzheimer' s disease2013
- Author(s)
  Ihara M
- Organizer
  Invited lecture : 19th Southampton Neuroscience Group (SoNG) Meeting
- Place of Presentation
  Southampton, UK
- Year and Date
  2013-09-19
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment2013
- Author(s)
  Ihara M
- Organizer
  Minisymposium (Animal models of VCI) . Vas-Cog2013
- Place of Presentation
  Toronto, Canada
- Year and Date
  2013-06-26
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment2013
- Author(s)
  Ihara M
- Organizer
  Plenary session (Special session on animal models of VCI) . Vas-Cog2013
- Place of Presentation
  Toronto, Canada
- Year and Date
  2013-06-26
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Animal models for vascular cognitive impairment due to large vessel disease. Stroke Symposium in National University of Singapore2011
- Author(s)
  Masafumi Ihara
- Organizer
  Stroke Symposium in National University of Singapore
- Place of Presentation
  Singapore(招待講演)
- Year and Date
  2011-10-31
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Animal models forvascular cognitive impairment due tolarge vessel disease2011
- Author(s)
  Masafumi Ihara
- Organizer
  Stroke Symposiumin National University of Singapore(Invited lecture)
- Place of Presentation
  Singapore
- Year and Date
  2011-10-31
- Data Source
  KAKENHI-PROJECT-23650182
[Presentation] βアミロイドの血管依存性クリアランス2011
- Author(s)
  猪原匡史
- Organizer
  日本認知症学会学術集会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Angiogenic andvasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011
- Author(s)
  Masafumi Ihara
- Organizer
  Vas-Cog
- Place of Presentation
  Lille, France
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-23650182
[Presentation] 脳低灌流によりβアミロイドの血管依存性クリアランスが障害される2011
- Author(s)
  猪原匡史, 他
- Organizer
  日本認知症学会学術集会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] モントリオール認知評価法MoCAはMMSEよりも皮質下血管性認知障害の検出感度が高い2011
- Author(s)
  猪原匡史, 岡本洋子, 伊東秀文, 高橋良輔
- Organizer
  第52回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-23650182
[Presentation] モントリオール認知評価法MoCAはMMSEよりも皮質下血管性認知障害の検出感度が高い2011
- Author(s)
  猪原匡史
- Organizer
  日本神経学会総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 脳低灌流によりβアミロイドの血管依存性クリアランスが障害される2011
- Author(s)
  猪原匡史, 岡本洋子, 眞木崇州, 鷲田和夫, 伊東秀文, 冨本秀和, 高橋良輔
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23650182
[Presentation] βアミロイドの血管依存性クリアランス2011
- Author(s)
  猪原匡史
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23650182
[Presentation] Angiogenic and vasoprotectivc effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice2011
- Author(s)
  Masafumi Ihara
- Organizer
  Vas-Cog2011
- Place of Presentation
  France
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Poster review session.2011
- Author(s)
  Masafumi Ihara
- Organizer
  Vas-Cog
- Place of Presentation
  Lille, France
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-23650182
[Presentation] Animal models for vascular cognitive impairment due to large vessel disease2011
- Author(s)
  Masafumi Ihara
- Organizer
  STROKE SYMPOSIUM
- Place of Presentation
  Singapore(CELS Auditorium)
- Year and Date
  2011-10-31
- Data Source
  KAKENHI-PROJECT-23650182
[Presentation] 皮質下血管性認知症患者におけるモントリオール認知評価スコアと身体活動度との相関2011
- Author(s)
  猪原匡史
- Organizer
  第30回日本認知症学会
- Place of Presentation
  東京
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23650182
[Presentation] CADASIL側頭極病変の成因に関する病理学的研究2010
- Author(s)
  猪原匡史, 山本由美, ら
- Organizer
  日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22650073
[Presentation] シロスタゾールの血液脳関門保護効果:一過性局所脳虚血モデルから得られたエビデンス2010
- Author(s)
  猪原匡史
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22650073
[Presentation] Animal models to study Stroke and VCI.2010
- Author(s)
  Masafumi Ihara
- Organizer
  Annual Neurosciences Conference in Eastern Africa
- Place of Presentation
  Nairobi, Kenya
- Year and Date
  2010-09-08
- Data Source
  KAKENHI-PROJECT-22650073
[Presentation] シロスタゾールの血液脳関門保護効果-一過性局所脳虚血モデルにおけるVirchow血栓形成3要因への作用について-2010
- Author(s)
  猪原匡史
- Organizer
  日本脳循環代謝学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-22650073
[Presentation] 混合型認知症の位置づけ, Vascular cognitive impairment(VCI)2010
- Author(s)
  猪原匡史
- Organizer
  日本認知症学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-22650073
[Presentation] A Mouse Model Characterizing Features of Vascular Dementia with Hippocampal Atrophy2010
- Author(s)
  Masafumi Ihara
- Organizer
  International Congress of Neuropathology (ICN2010)
- Place of Presentation
  Salzburg, Austria
- Year and Date
  2010-09-13
- Data Source
  KAKENHI-PROJECT-22650073
[Presentation] 脳血管障害に基づく認知機能障害の病態2010
- Author(s)
  猪原匡史
- Organizer
  日本脳卒中学会
- Place of Presentation
  盛岡
- Year and Date
  2010-04-15
- Data Source
  KAKENHI-PROJECT-22650073
[Presentation] 海馬萎縮を伴う血管性認知症の新規モデルマウス2010
- Author(s)
  猪原匡史
- Organizer
  日本脳循環代謝学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-22650073
[Presentation] シロスタゾールによる血管依存性βアミロイドクリアランスの促進．
- Author(s)
  猪原匡史
- Organizer
  脳循環代謝学会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] シンポジウム5「血管性認知障害」血管性認知障害の病態－モデル動物を用いて明らかとなった知見－
- Author(s)
  猪原匡史
- Organizer
  第39回日本脳卒中学会総会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment.
- Author(s)
  Masafumi Ihara.
- Organizer
  Plenary session (Special session on animal models of VCI). Vas-Cog2013
- Place of Presentation
  Toronto
- Invited
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment.
- Author(s)
  Masafumi Ihara.
- Organizer
  Minisymposium (Animal models of VCI). Vas-Cog2013
- Place of Presentation
  Toronto
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 「血管病としての認知症」
- Author(s)
  猪原匡史
- Organizer
  Vas-Cog Japan
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] 血管病としての認知症～その制圧へ向けた試み～
- Author(s)
  猪原匡史
- Organizer
  第3回VAS-COG Japan 2012
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] シンポジウム5「血管性認知障害」血管性認知障害の病態－モデル動物を用いて明らかとなった知見－
- Author(s)
  猪原匡史
- Organizer
  第39回日本脳卒中学会総会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 「長寿遺伝子」SIRT1はeNOSを脱アセチル化することで脳低灌流侵襲に対する抵抗性を賦与する
- Author(s)
  猪原匡史
- Organizer
  脳卒中学会
- Place of Presentation
  広島
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical
- Author(s)
  Masafumi Ihara
- Organizer
  3rd CAA meeting (Plenary lecture)
- Place of Presentation
  Leiden
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Symposium S（4）-1.Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment （VCI）．Cerebral amyloid angiopathy and cognitive impairment．
- Author(s)
  Masafumi Ihara.
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Generating rodent models of chronic cerebral hypoperfusion and investigating the pathogenesis of vascular cognitive impairment.
- Author(s)
  Masafumi Ihara.
- Organizer
  Plenary session (Special session on animal models of VCI). Vas-Cog2013
- Place of Presentation
  Toronto
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 「認知症の発症にかかわる脳血管の機能」．
- Author(s)
  猪原匡史
- Organizer
  脳心血管抗加齢研究会2013
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Bench to bedside: using mouse models to identify new treatment approaches for Alzheimer’s disease.
- Author(s)
  Masafumi Ihara.
- Organizer
  Invited lecture: 19th Southampton Neuroscience Group (SoNG) Meeting
- Place of Presentation
  Southampton
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 小血管病における虚血性線条体障害：11C-フルマゼニルPETによる解析
- Author(s)
  猪原匡史
- Organizer
  第5回J-CAN (Japanese Consortium for Age-related Neurodegenerative disorders) 2012
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Bench to bedside: using mouse models to identify new treatment approaches for Alzheimer’s disease.
- Author(s)
  Masafumi Ihara.
- Organizer
  Invited lecture: 19th Southampton Neuroscience Group (SoNG) Meeting
- Place of Presentation
  Southampton
- Invited
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] 認知症患者における抗血栓療法の有効性と安全性に関する分子病理学的検討
- Author(s)
  猪原匡史
- Organizer
  第37回日本脳卒中学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 「血管病としての認知症」
- Author(s)
  猪原匡史
- Organizer
  Vas-Cog Japan
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 「認知症の発症にかかわる脳血管の機能」．
- Author(s)
  猪原匡史
- Organizer
  脳心血管抗加齢研究会2013
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical
- Author(s)
  Masafumi Ihara
- Organizer
  World Stroke Congress
- Place of Presentation
  Brazilia
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] シロスタゾールによる血管依存性βアミロイドクリアランスの促進．
- Author(s)
  猪原匡史
- Organizer
  脳循環代謝学会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題．
- Author(s)
  Masafumi Ihara.
- Organizer
  Novel mechanism and therapy to treat patient with dementia. Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] 認知症における脳血管病変
- Author(s)
  猪原匡史
- Organizer
  第3回VAS-COG Japan 2012
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Symposium S（4）-1.Vascular Dementia and Its Associated Conditions-Vascular Cognitive Impairment （VCI）．Cerebral amyloid angiopathy and cognitive impairment．
- Author(s)
  Masafumi Ihara.
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] シンポジウム１．血管性認知症の最先端「血管性認知症とAlzheimer病理」
- Author(s)
  猪原匡史
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば
- Invited
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] S2-5-2中枢神経疾患治療に対するトランスレーショナルリサーチの現状とその課題．
- Author(s)
  Masafumi Ihara.
- Organizer
  Novel mechanism and therapy to treat patient with dementia. Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] 皮質下血管性認知症患者におけるモントリオール認知評価スコアと身体活動度との相関
- Author(s)
  猪原匡史
- Organizer
  第53回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390233
[Presentation] Lessons from rodent models characterizing features of vascular cognitive impairment.
- Author(s)
  Masafumi Ihara.
- Organizer
  Minisymposium (Animal models of VCI). Vas-Cog2013
- Place of Presentation
  Toronto
- Invited
- Data Source
  KAKENHI-PROJECT-25640031
[Presentation] Animal models of brain hypoperfusion and cognitive impairment
- Author(s)
  Masafumi Ihara
- Organizer
  BRAIN AGEING AND DEMENTIA IN DEVELOPING COUNTRIES 2012
- Place of Presentation
  Nairobi
- Invited
- Data Source
  KAKENHI-PROJECT-23390233

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# of Collaborated Products: 1 results
67. KAWAMOTO Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
68. SONE Masakatsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
69. 佐藤哲子

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
70. 百田善弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
71. 松山知宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
72. 高橋良輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
73. 伊東秀文

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
74. 福山秀直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
75. 山陰一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
76. SHOHAB YOUSSEFIAN

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
77. 小泉昭夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
78. 田浦大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
79. 田中篤太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
80. 田中都

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ihara Masafumi 猪原 匡史

IHARA Masafumi 猪原 匡史

猪原 匡史 イハラ マサフミ

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Collaborative dental-medical research on the mechanism of intracerebral hemorrhage via cerebrovascular matrisome injury by oral bacteriaPrincipal Investigator

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日韓台合同CADASIL1000人レジストリと国際治験基盤の構築Principal Investigator

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Prognostic role of white matter lesion topography in cerebrovascular disordersPrincipal Investigator

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Construction of an evaluation system for feeding and swallowing disorders and sarcopenia after stroke and search for key molecules in the brain-gut-muscle linkagePrincipal Investigator

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Dysphagia severity and decision making algorithm after acute stoke in the elderlyPrincipal Investigator

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Ihara Masafumi 猪原匡史

IHARA Masafumi 猪原匡史

猪原匡史イハラマサフミ