Ono Masahiro 小野正博

… Alternative Names

ONO Masahiro 小野正博

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Researcher Number	80336180
Other IDs
Affiliation (Current)	2025: 京都大学, 薬学研究科, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 京都大学, 薬学研究科, 教授 2016: 京都大学, 薬学研究科, 准教授 2014 – 2016: 京都大学, 薬学研究科(研究院), 准教授 2013: 京都大学, 薬学研究科, 准教授 2011: Kyoto University, 薬学研究科(研究院), 准教授 … More 2007 – 2010: Kyoto University, 薬学研究科, 准教授 2007 – 2008: 京都大学, 大学院・薬学研究科, 准教授 2005 – 2006: 長崎大学, 大学院医歯薬学総合研究科, 助手 2002 – 2005: 長崎大学, 大学院・医歯薬学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related / Biological Sciences / Biological Sciences / Medium-sized Section 52:General internal medicine and related fields / Neuroscience and related fields / Applied pharmacology / Radiation science Except Principal Investigator Radiation science / Physical pharmacy / Basic Section 52040:Radiological sciences-related / Nerve anatomy/Neuropathology / Neuroscience and related fields
Keywords	Principal Investigator イメージング / アルツハイマー病 / SPECT / βアミロイド / タウ / アミロイドβ / PET / 放射性医薬品 / パーキンソン病 / αシヌクレイン … More / オリゴマー / 診断 / 分子イメージング / 画像化 / 痴呆 / インビボイメージング / 老人斑アミロイド / ALS / TDP-43 / レビー小体病 / プローブ / Parkinson's disease / imaging / α-synuclein / タウイメージング / アミロイド / 認知症 / 金属錯体 / 脳アミロイドアンギオパチー / 画像診断 / 光 / 核医学 / 近赤外蛍光 / マルチモーダル / 造影剤 / MRI / アミロイドβ蛋白 / 放射性薬剤 / 神経変性疾患 / アミロイド凝集体 / 老人斑 / 放射線 / 脳神経疾患 … More Except Principal Investigator 分子イメージング / アルツハイマー病 / PET / イメージング / 痴呆 / アミロイド / 脳神経疾患 / チェレンコフ光 / SPECT / 認知症 / 糖尿病 / アミロイドβ蛋白 / オージェ電子 / 画像診断 / 放射線 / 放射性薬剤 / プレターゲティング / 抗体 / 光免疫療法 / 核医学治療 / アミロイドβ / シロスタゾール / 抗糖化 / 脳循環障害 / 抗糖化薬 / オリゴマー / 病理学 / 脳・神経 / 神経科学 / 脳アミロイド血管症 / タウ / 抗糖化作用 / タキシフォリン / 粒子線治療 / 内照射治療 / 粒子線 / Aβ凝集体 / 膵β細胞 / 内用放射線治療 / がん治療 / 光線照射療法 / 近赤外光 / 光音響法 / 脳エネルギー代謝 / 多発性硬化症 / flavone / Alzheimer's disease / molecular imaging / amyloid β protein / 放射性金属核種 / 放射性医薬品 / インビボ画像化 / 老人斑アミロイド / 画像化 / 神経変性疾患 / フラボン誘導体 / テクネチウム-99m / 画像診断薬剤 / フラボン / 診断 / GSK-3β / タウオパチー / 早期診断 / 膵島β細胞 / 放射線治療 / トランスレーショナルリサーチ / 放射線画像診断 / アルツハィマー病 / ベンゾフラン / プリオン病 / 多孔性樹脂 / 多孔性吸着剤 / Ga-68 / Ge-68 / ガリウム / ジェネレータ Less

アルツハイマー病の診断・治療に資する次世代アミロイドβイメージング法の開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
核医学治療と光免疫療法を融合した革新的がん治療法の創生
- Principal Investigator
  
  花岡宏史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kansai Medical University
神経難病ALSにおけるTDP-43凝集体の生体分子イメージング法の開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kyoto University
Development of nuclear medicine imaging method targeting alfa-synuclein aggregates for diagnosis and treatment of Lewy body disease.Principal Investigator
- Principal Investigator
  
  Ono Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
Development of new radiation therapy for Alzheimer's disease using a combination of particle beam and auger electron
- Principal Investigator
  
  Kiyono Yasushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Neuroscience and related fields
- Research Institution
  University of Fukui
Development of amyloid oligomer imaging for early diagnosis of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Ono Masahiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Neuroscience and related fields
- Research Institution
  Kyoto University
SPECTによるタウイメージング法の開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Development of nuclear medical imaging probes that target alfa-synuclein in Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  Ono Masahiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Development of PET probes targeting pancreatic b-cells for early diagnosis and preemptive medicine of diabetes.
- Principal Investigator
  
  Saji Hideo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Basic research for multifaceted PET analysis of multiple sclerosis based on the neuronal-glial-blood vessel linkage
- Principal Investigator
  
  TEMMA TAKASHI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University of Pharmaceutical Sciences
  National Cardiovascular Center Research Institute
βアミロイドおよびタウを標的としたSPECTイメージングプローブの開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Development of a cancer-targeted diagnosis-therapy workflow system utilizing photoacoustic effect with near-infrared light
- Principal Investigator
  
  Saji Hideo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of anti-glycosylation agents for Alzheimer disease
- Principal Investigator
  
  IHARA MASAFUMI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  National Cardiovascular Center Research Institute
Development of nuclear medical imaging probes targeting cerebral amyloid antipathyPrincipal Investigator
- Principal Investigator
  
  Ono Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Development of a novel Cherenkov imaging method for evaluating the effect of internal radiation therapy
- Principal Investigator
  
  Hideo Saji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of nuclear medical imaging probes targeting GSK-3beta for early diagnosis of tauopathy
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
アルツハイマー病における神経原線維変化を標的とした分子イメージングプローブの開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
GSKー3βを標的とするタウオパチー診断用分子イメージング法の開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Development of molecular imaging probes for measurement of mass in pancreatic islets.
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
融合画像診断を目指したマルチモーダル分子イメージングプローブの開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Development of molecular imaging probes for β-amyloid and tau in Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  ONO Masahiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Development of probes for the systematic analysis of Alzheimer's disease : establishment of a new diagnostic imaging.
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
オージェ電子放出ハロゲンを利用したアルツハイマー病の新しい治療法の開発
- Principal Investigator
  
  Kiyono Yasushi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  University of Fukui
Development of production-system of PET imaging agents without cyclotron.
- Principal Investigator
  
  NAKAYAMA Morio
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
異常型プリオン蛋白結合性化合物の探索とその分子イメージングへの応用
- Principal Investigator
  
  中山守雄
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Nagasaki University
脳内アミロイドβ蛋白の検出を目的とした新規分子イメージングプローブの開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
  Nagasaki University
アルツハイマー病の早期診断を目的とする老人斑アミロイド画像化薬剤の開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Nagasaki University
アルツハイマー病脳における老人斑アミロイドの画像化Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
In Vivo Imaging of β-Amyloid Plaques in Alzheimer's Disease Brains.
- Principal Investigator
  
  NAKAYAMA Morio
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
アルツハイマー病脳における老人斑アミロイドの画像化Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
アルツハイマー病の早期診断を目的とした新規放射性薬剤の開発Principal Investigator
- Principal Investigator
  
  小野正博
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Nagasaki University

[Book] ナノバイオ技術と最新創薬応用研究2012
- Author(s)
  佐治英郎, 小野正博, 天滿敬, 上田真史, 木村寛之
- Data Source
  KAKENHI-PROJECT-22249046
[Journal Article] アミロイドイメージング剤の開発における薬学的貢献2023
- Author(s)
  小野正博
- Journal Title
  
  核医学技術
  
  Volume: 43 Pages: 45-49
- Data Source
  KAKENHI-PROJECT-20H03622
[Journal Article] In Vivo Near-Infrared Fluorescence Imaging Selective for Soluble Amyloid β Aggregates Using y-Shaped BODIPY Derivative2023
- Author(s)
  Takahiro Akasaka, Hiroyuki Watanabe, and Masahiro Ono
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 66 Issue: 20 Pages: 14029-14046
- DOI
  10.1021/acs.jmedchem.3c01057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19490
[Journal Article] Structure-Activity Relationships of Styrylquinoline and Styrylquinoxaline Derivatives as α-Synuclein Imaging Probes2022
- Author(s)
  Nakagawa K, Watanabe H, Kaide S, Ono M.
- Journal Title
  
  ACS Med Chem Lett
  
  Volume: 13 Issue: 10 Pages: 1598-1605
- DOI
  10.1021/acsmedchemlett.2c00279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622
[Journal Article] Chalcone Analogue as New Candidate for Selective Detection of α-Synuclein Pathology2022
- Author(s)
  Kaide S, Watanabe H, Iikuni S, Hasegawa M, Itoh K, Ono M
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 13 Issue: 1 Pages: 16-26
- DOI
  10.1021/acschemneuro.1c00441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622, KAKENHI-PROJECT-20J14694
[Journal Article] Synthesis and Evaluation of 18F-Labeled Chalcone Analogue for Detection of α-Synuclein Aggregates in the Brain Using the Mouse Model2022
- Author(s)
  Kaide S, Watanabe H, Iikuni S, Hasegawa M, Ono M.
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 13 Issue: 20 Pages: 2982-2990
- DOI
  10.1021/acschemneuro.2c00473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622
[Journal Article] Synthesis and evaluation of novel radioiodinated phenylbenzofuranone derivatives as α-synuclein imaging probes2022
- Author(s)
  Akasaka T, Watanabe H, Kaide S, Iikuni S, Hasegawa M, Ono M
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 64 Pages: 128679-128679
- DOI
  10.1016/j.bmcl.2022.128679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622
[Journal Article] Identification and Evaluation of Bisquinoline Scaffold as a New Candidate for α-Synuclein-PET Imaging2020
- Author(s)
  Kaide S, Watanabe H, Shimizu Y, Iikuni S, Nakamoto Y, Hasegawa M, Itoh K, Ono M.
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 11 Issue: 24 Pages: 4254-4261
- DOI
  10.1021/acschemneuro.0c00523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622, KAKENHI-PROJECT-20J14694
[Journal Article] Structure-Activity Relationships of Radioiodinated Benzoimidazopyridine Derivatives for Detection of Tau Pathology2018
- Author(s)
  Kaide S, Ono M, Watanabe H, Kitada A, Yoshimura M, Shimizu Y, Ihara M, Saji H.
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 9 Issue: 5 Pages: 478-483
- DOI
  10.1021/acsmedchemlett.8b00092
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05694, KAKENHI-PROJECT-17H05092
[Journal Article] Novel benzothiazole derivatives as fluorescent probes for detection of β-amyloid and α-synuclein aggregates2017
- Author(s)
  Watanabe H, Ono M, Ariyoshi T, Katayanagi R, Saji H
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 8 Issue: 8 Pages: 1656-1662
- DOI
  10.1021/acschemneuro.6b00450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04260
[Journal Article] Synthesis and biological evaluation of novel radioiodinated benzimidazole derivatives for imaging α-synuclein aggregates2017
- Author(s)
  Watanabe H, Ariyoshi T, Ozaki A, Ihara M, Ono M, Saji H
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 25 Issue: 24 Pages: 6398-6403
- DOI
  10.1016/j.bmc.2017.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04260, KAKENHI-PROJECT-17H05092
[Journal Article] Indocyanine green-labeled polysarcosine for in vivo photoacoustic tumor imaging.2017
- Author(s)
  Sano K, Ohashi M, Kanazaki K, Makino A, Ding N, Deguchi J, Kanada Y, Ono M, Saji H.
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 28 Issue: 4 Pages: 1024-1030
- DOI
  10.1021/acs.bioconjchem.6b00715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04637
[Journal Article] Imaging of Cerebral Amyloid Angiopathy with Bivalent 99mTc-Hydroxamamide Complexes2016
- Author(s)
  Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Hiroyuki Kimura, Hatsue Ishibashi-Ueda, Yoko Okamoto, Masafumi Ihara, Hideo Saji.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 25990-25990
- DOI
  10.1038/srep25990
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J05493, KAKENHI-PROJECT-26293274
[Journal Article] Novel Bivalent 99mTc-Complex with N-Methyl-Substituted Hydroxamamide as Probe for Imaging of Cerebral Amyloid Angiopathy2016
- Author(s)
  Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Masashi Yoshimura, Hatsue Ishibashi-Ueda, Masafumi Ihara, Hideo Saji.
- Journal Title
  
  PLoS One
  
  Volume: 11(9) Issue: 9 Pages: e0163969-e0163969
- DOI
  10.1371/journal.pone.0163969
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J05493, KAKENHI-PROJECT-26293274
[Journal Article] Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging.2016
- Author(s)
  Kanazaki K, Sano K, Makino A, Yamauchi F, Takahashi A, Homma T, Ono M, Saji H.
- Journal Title
  
  J Control Release
  
  Volume: 226 Pages: 115-123
- DOI
  10.1016/j.jconrel.2016.02.017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04637
[Journal Article] Polyoxazoline multivalently conjugated with indocyanine green for sensitive in vivo photoacoustic imaging of tumors.2016
- Author(s)
  Kanazaki K, Sano K, Makino A, Homma T, Ono M, Saji H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 33798-33798
- DOI
  10.1038/srep33798
- NAID
  120005850222
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04637
[Journal Article] Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease2016
- Author(s)
  Ono M, Watanabe H, Kitada A, Matsumura K, Ihara M, Saji H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 34197-34197
- DOI
  10.1038/srep34197
- NAID
  120005997847
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01555
[Journal Article] Development of anti-HER2 fragment antibody conjugated to iron oxide nanoparticles for in vivo HER2-targeted photoacoustic tumor imaging.2015
- Author(s)
  Kanazaki K, Sano K, Makino A, Shimizu Y, Yamauchi F, Ogawa S, Ding N, Yano T, Temma T, Ono M, Saji H.
- Journal Title
  
  Nanomedicine, NBM
  
  Volume: 11 Issue: 8 Pages: 2051-2060
- DOI
  10.1016/j.nano.2015.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04637
[Journal Article] Structure-Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents that Selectively Detect Neurofibrillary Tangles in Alzheimer’s Disease Brains2015
- Author(s)
  Matsumura K, Ono M, Kitada A, Watanabe H, Yoshimura M, Iikuni S, Kimura H, Okamoto Y, Ihara M, Saji H.
- Journal Title
  
  J Med Chem
  
  Volume: 58 Issue: 18 Pages: 7241-7257
- DOI
  10.1021/acs.jmedchem.5b00440
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01555, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-14J05961
[Journal Article] Development of photostabilized asymmetrical cyanine dyes for in vivo photoacoustic imaging of tumors.2015
- Author(s)
  Onoe S, Temma T, Kanazaki K, Ono M, Saji H.
- Journal Title
  
  J Biomed Opt
  
  Volume: 20 Issue: 9 Pages: 096006-096006
- DOI
  10.1117/1.jbo.20.9.096006
- NAID
  120005678212
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04637
[Journal Article] microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.2015
- Author(s)
  Kim J, Yoon H, Horie T, Burchett JM, Restivo JL, Rotllan N, Ramírez CM, Verghese PB, Ihara M, Hoe HS, Esau C, Fernández-Hernando C, Holtzman DM, Cirrito JR, Ono K, Kim J.
- Journal Title
  
  J Neurosci.
  
  Volume: 35(44) Issue: 44 Pages: 14717-26
- DOI
  10.1523/jneurosci.2053-15.2015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461144, KAKENHI-PUBLICLY-26116716, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-26293186
[Journal Article] In vivo photoacoustic imaging of cancer using indocyanine green-labeled monoclonal antibody targeting the epidermal growth factor receptor.2015
- Author(s)
  Sano K, Ohashi M, Kanazaki K, Ding N, Deguchi J, Kanada Y, Ono M, Saji H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 464 Issue: 3 Pages: 820-825
- DOI
  10.1016/j.bbrc.2015.07.042
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04637
[Journal Article] Enhancement of Binding Affinity for Amyloid Aggregates by Multivalent Interactions of 99mTc-Hydroxamamide Complexes2014
- Author(s)
  Iikuni S, Ono M, Watanabe H, Matsumura K, Yoshimura M, Harada N, Kimura H, Nakayama M, Saji H.
- Journal Title
  
  Mol Pharm
  
  Volume: 11 Issue: 4 Pages: 1132-1139
- DOI
  10.1021/mp400499y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293274
[Journal Article] Synthesis and biological evaluation of novel styryl benzimidazole derivatives as probes for imaging of neurofibrillary tangles in Alzheimer's disease.2013
- Author(s)
  Matsumura K, Ono M, Yoshimura M, Kimura H, Watanabe H, Okamoto Y, Ihara M, Takahashi R, Saji H.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 21 Issue: 11 Pages: 3356-3362
- DOI
  10.1016/j.bmc.2013.02.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-24659564, KAKENHI-PROJECT-25640031
[Journal Article] Molecular Imaging of β-Amyloid Plaques with Near-Infrared BODIPY-based Fluorescent Probes2013
- Author(s)
  Hiroyuki Watanabe, Masahiro Ono, Kenji Matsumura, Masashi Yoshimura, Hiroyuki Kimura, Hideo Saji
- Journal Title
  
  Molecular Imaging
  
  Volume: 12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046
[Journal Article] Novel design and synthesis of a radioiodinated glycolipid analog as an acceptor substrate for N-acetylglucosaminyltransferase V2013
- Author(s)
  Kenji Arimitsu, Hiroyuki Kimura, Tetsuya Kajimoto, Masahiro Ono,Yoshiro Ohmomo, Masayuki Yamashita, Manabu Node, Hideo Saji
- Journal Title
  
  Journal of Labelled Compounds and Radiopharmaceuticals
  
  Volume: 56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046
[Journal Article] Synthesis and biological evaluation of novel styryl benzimidazole derivatives as probes for imaging of neurofibrillary tangles in Alzheimer's disease2013
- Author(s)
  Matsumura K, Ono M, Yoshimura M, Kimura H, Watanabe H, Okamoto Y, Ihara M, Takahashi R, Saji H
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 21(11) Pages: 3356-62
- Data Source
  KAKENHI-PROJECT-24659564
[Journal Article] BODIPY-based molecular probe for imaging of cerebral β-amyloid plaques2012
- Author(s)
  Masahiro Ono, Hiroyuki Watanabe, Hiroyuki Kimura, Hideo Saji
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 18;3(4) Pages: 319-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046
[Journal Article] 18F-Labeled phenyldiazenyl benzothiazole for in vivo imaging of neurofibrillary tangles in Alzheimer’s disease brains.2012
- Author(s)
  Matsumura K, Ono M, Kimura H, Ueda M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H.
- Journal Title
  
  ACS Medicinal Chemistry Letter
  
  Volume: 3 Pages: 58-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659564
[Journal Article] ^<18>F-Labeled phenyl benzothiazole for in vivo imaging of neurofibrillary tangles in Alzheimer's disease brains2012
- Author(s)
  Matsumura K, Ono M, Kimura H, Ueda M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H.
- Journal Title
  
  ACS Medicinal Chemistry Letter
  
  Volume: 3 Pages: 58-62
- Data Source
  KAKENHI-PROJECT-24659564
[Journal Article] Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Novel PET/SPECT imaging probes for diagnosis of Alzheimer’s disease.2012
- Author(s)
  Ono M, Saji H
- Journal Title
  
  Journal of Pharmacological Science
  
  Volume: 118 Pages: 338-344
- NAID
  10030455553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659564
[Journal Article] Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer's disease2012
- Author(s)
  Ono M, Saji H
- Journal Title
  
  Journal of Pharmacological Science
  
  Volume: 118 Pages: 338-344
- Data Source
  KAKENHI-PROJECT-24659564
[Journal Article] Microwave-Assisted Synthesis of Organometallic Complexes of 99mTc(CO)3 and Re(CO)3: Its Application to Radiopharmaceuticals2012
- Author(s)
  Hiroyuki Kimura, Daisuke Mori, Naoya Harada, Masahiro Ono, Yoshiro Ohmomo, Tetsuya Kajimoto, Hidekazu Kawashima, Hideo Saji
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 60 Issue: 1 Pages: 79-85
- DOI
  10.1248/cpb.60.79
- NAID
  130001852351
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046, KAKENHI-PROJECT-23791413
[Journal Article] Microwave-assisted Synthesis of Organometallic Complexes of ^99mTc(CO)_3 and Re(CO)_3: Its Application to Radiopharmaceuticals.2012
- Author(s)
  Hiroyuki Kimura, Daisuke Mori, Naoya harada, .Masahiro Ono, Yoshiro Ohmomo, Tetsuya Kajimoto, Hidekazu Kawashima, Hideo Saji
- Journal Title
  
  Chemical & Pharmaceutical Bulletin
  
  Volume: 60(1) Pages: 79-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046
[Journal Article] Diphenylpropynone derivatives as probes for imaging β-amyloid plaques.2011
- Author(s)
  Ono M, Watanabe H, Watanabe R, Haratake M, Nakayama M, Saji H.
- Journal Title
  
  Bioorganic & Medicinal Chemistry 21
  
  Pages: 117-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Diphenylpropynone derivatives as probes for imaging β-amyloid plaques2011
- Author(s)
  Ono M, Watanabe H, Watanabe R, Haratake M, Nakayama M, Saji H
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21 Pages: 117-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Synthesis and biological evaluation of indole-chalcone derivatives as β-amyloid imaging probe.2011
- Author(s)
  Cui M, Ono M, Kimura H, Liu BL, Saji H
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 21
  
  Pages: 980-982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Synthesis and biological evaluation of indole-chalcone derivatives as β-amyloid imaging probe2011
- Author(s)
  Cui M, Ono M, Kimura H, Liu BL, Saji H
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21 Pages: 980-982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Diphenylpropynone derivatives as probes for imaging β-amyloid plaques2011
- Author(s)
  Ono M, Watanabe H, Watanabe R, Haratake M, Nakayama M, Saji H
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21 Pages: 117-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659288
[Journal Article] Development of dual functional SPECT/fluorescent probes for imaging cerebral β-amyloid plaques2010
- Author(s)
  Ono M, Ishikawa M, Kimura H, Hayashi S, Matsumura K, Watanabe H, Shimizu Y, Cheng Y, Cui M, Kawashima H, Saji H
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 20 Pages: 3885-3888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659288
[Journal Article] Synthesis and evaluation of novel chalcone derivatives with ^<99m>Tc/Re complexes as potential probes for detection of β-amyloid plaques2010
- Author(s)
  Ono M, Ikeoka R, Watanabe H, Kimura H, Fuchigami T, Haratake M, Saji H, Nakayama M
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 1 Pages: 598-607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Synthesis and characterization of novel phenylindoles as potential probes for imaging of β-amyloid plaques in the brain.2010
- Author(s)
  Watanabe H, Ono M, Haratake M, Kobashi N, Saji H, Nakayama M.
- Journal Title
  
  Bioorganic & Medicinal Chemistry 18
  
  Pages: 4740-4746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Novel benzofurans with ^<99m>Tc complexes as probes for imaging cerebral β-amyloid plaques using single photon emission computed tomography2010
- Author(s)
  Ono M, Fuchi Y, Fuchigami T, Kobashi N, Kimura H, Haratake M, Saji H, Nakayama M
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 1 Pages: 443-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659288
[Journal Article] Synthesis and evaluation of novel chalcone derivatives with ^<99m>Tc/Re complexes as potential probes for detection of β-amyloid plaques.2010
- Author(s)
  Ono M, Ikeoka R, Watanabe H, Kimura H, Fuchigami T, Haratake M, Saji H, Nakayama M.
- Journal Title
  
  ACS Chemical Neuroscience 1
  
  Pages: 598-607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] ^<99m>Tc/Re complexes based on flavone and aurone as SPECT probes for imaging cerebral β-amyloid plaques2010
- Author(s)
  Ono M, Ikeoka R, Watanabe H, Kimura H, Fuchigami T, Haratake M, Saji H, Nakayama M
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 20 Pages: 5742-5748
- NAID
  120006984924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Novel benzofurans with ^<99m>Tc complexes as probes for imaging cerebral β-amyloid plaques using single photon emission computed tomography2010
- Author(s)
  Ono M, Fuchi Y, Fuchigami T, Kobashi N, Kimura H, Haratake M, Saji H, Nakayama M
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 1 Pages: 443-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Fluorinated benzofuran derivatives for PET imaging of β-amyloid plaques in Alzheimer's disease brains.2010
- Author(s)
  Cheng Y, Ono M, Kimura H, Kagawa S, Nishii R, Kawashima H, Saji H.
- Journal Title
  
  ACS Medicinal Chemistry Letters 1
  
  Pages: 321-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Fluorinated benzofuran derivatives for PET imaging of β-amyloid plaques in Alzheimer's disease brains2010
- Author(s)
  Cheng Y, Ono M, Kimura H, Kagawa S, Nishii R, Kawashima H, Saji H
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 1 Pages: 321-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Synthesis and evaluation of novel chalcone derivatives with ^<99m>Tc/Re complexes as potential probes for detection of β-amyloid plaques2010
- Author(s)
  Ono M, Ikeoka R, Watanabe H, Kimura H, Fuchigami T, Haratake M, Saji H, Nakayama M
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 1 Pages: 598-607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659288
[Journal Article] Synthesis and characterization of novel phenylindoles as potential probes for imaging of β-amyloid plaques in the brain2010
- Author(s)
  Watanabe H, Ono M, Haratake M, Kobashi N, Saji H, Nakayama M
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 18 Pages: 4740-4746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] ^<99m>Tc/Re complexes based on flavone and aurone as SPECT probes for imaging cerebral β-amyloid plaques.2010
- Author(s)
  Ono M, Ikeoka R, Watanabe H, Kimura H, Fuchigami T, Haratake M, Saji H, Nakayama M.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 20
  
  Pages: 5742-5748
- NAID
  120006984924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Novel benzofurans with ^<99m>Tc complexes as probes for imaging cerebral β-amyloid plaques using single photon emission computed tomography.2010
- Author(s)
  Ono M, Fuchi Y, Fuchigami T, Kobashi N, Kimura H, Haratake M, Saji H, Nakayama M.
- Journal Title
  
  ACS Medicinal Chemistry 1
  
  Pages: 443-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] ^<99m>Tc/Re complexes based on flavone and aurone as SPECT probes for imaging cerebral β-amyloid plaques2010
- Author(s)
  Ono M, Ikeoka R, Watanabe H, Kimura H, Fuchigami T, Haratake M, Saji H, Nakayama M
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 20 Pages: 5742-5748
- NAID
  120006984924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659288
[Journal Article] Novel Radioiodinated Aurones as probes for SPECT imaging of β-amyloid plaques in the brain2009
- Author(s)
  Y. Maya, M. Ono, H. Watanabe, M. Haratake, H. Saji, M. Nakayama
- Journal Title
  
  Bioconjugate Chemistry 20
  
  Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Fluoro-pegylated chalcones as positron emission tomography probes for in vivo imaging of β-amyloid plaques in Alzheimer's disease2009
- Author(s)
  Ono M, Watanabe R, Kawashima H, et al.
- Journal Title
  
  Journal of Medicinal Chemistry 52
  
  Pages: 6394-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] 18F-labeled flavones for in vivo imaging of beta-amyloid plaques in Alzheimer's disease2009
- Author(s)
  Ono M, Watanabe R, Kawashima H, et.al.
- Journal Title
  
  Bioorg Med Chem 17
  
  Pages: 2069-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Fluoro-pegylated chalcones as positron emission tomography probes for in vivo imaging of β-amyloid plaques in Alzheimer's disease2009
- Author(s)
  Ono M, Watanabe R, Kawasima H, Saji H, et al.
- Journal Title
  
  Journal of Medicinal Chemistry Vol.52
  
  Pages: 6394-6401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] Fluoro-pegylated chalcones as poitron emission tomography probes for in vivo imaging of β-amyloid plaques in Alzheimer's b2009
- Author(s)
  Ono M, et al.
- Journal Title
  
  Journal of Medicinal Chemistry 52
  
  Pages: 6394-6401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Synthesis and biological evaluation of radioiodinated 2,5-diphenyl-1,3,4-oxadiazoles for detecting β-amyloid plaques in the brain.2009
- Author(s)
  Watanabe H, Ono M, Ikeoka R, Haratake M, Saji H, Nakayama M.
- Journal Title
  
  Bioorganic and Medicinal Chemistry 17
  
  Pages: 6402-6406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] ^<18>F-labeled flavones for in vivo imaging of beta-amyloid plaques in Alzheimer's brains2009
- Author(s)
  Ono M, Watanabe R, Kawashima H, et al
- Journal Title
  
  Bioorganic Medicinal Chemistry 17
  
  Pages: 2069-2076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] 18F-labeled flavones for in vivo imaging of ss-amyloid plaques in Alzheimer's brains2009
- Author(s)
  Ono M, et al.
- Journal Title
  
  Bioorganic and Medicinal Chemistry 17
  
  Pages: 2069-2076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Molecular imaging by PET/SPECT.2009
- Author(s)
  Ono M.
- Journal Title
  
  Yakugaku Zasshi 129
  
  Pages: 279-287
- NAID
  110007123176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Novel radioiodinated aurones as probes for SPECT imaging of beta-amyloid plaques in the brain2009
- Author(s)
  Maya Y, Ono M, Watanabe H, et al
- Journal Title
  
  Bioconjugate Chemistry 20
  
  Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] Fluoro-pegylated chalcones as positron emission tomography probes for in vivo imaging of β-amyloid plaques in Alzheimer's disease.2009
- Author(s)
  Ono M, Watanabe R, Kawashima H, Cheng Y, Kimura H, Watanabe H, Haratake M, Saji H, Nakayama M.
- Journal Title
  
  Journal of Medicinal Chemistry 52
  
  Pages: 6394-6401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] ^<18>F-labeled flavones for in vivo imaging of β-amyloid plaques in Alzheimer's brains.2009
- Author(s)
  Ono M, Watanabe R, Kawashima H, Kawai T, Watanabe H, Haratake M, Saji H, Nakayama M.
- Journal Title
  
  Bioorganic and Medicinal Chemistry 17
  
  Pages: 2009-2076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Push-pull benzothiazole derivatives as probes for detecting ss-amyloid plaques in Alzheimer's brains.2009
- Author(s)
  Ono M, et al.
- Journal Title
  
  Bioorganic and Medicinal Chemistry 17
  
  Pages: 6402-6406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Novel radioiodinated aurones as probes for SPECT imaging of beta-amyloid plaques in the brain2009
- Author(s)
  Maya Y, Ono M, Watanabe H, et.al.
- Journal Title
  
  Bioconjugate Chem 20
  
  Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Novel Radioiodinated Aurones as Probes for SPECT Imaging of β-Amyloid Plaques in the Brain.2009
- Author(s)
  Y. Maya, M. Ono, H. Watanabe, M. Haratake, H. Saji, M. Nakayama
- Journal Title
  
  Bioconjugate Chemistry 20
  
  Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Molecular imaging by PET/SPECT2009
- Author(s)
  Ono M
- Journal Title
  
  Yakugaku Zasshi 129
  
  Pages: 279-287
- NAID
  110007123176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Development of positron-emission tomography /single-photon emission computed tomography imaging probes for in vivo detection of β-amyloid plaques in Alzheimer's brains.2009
- Author(s)
  Ono M.
- Journal Title
  
  Chemical & Pharmaceutical Bulletin 57
  
  Pages: 1029-1039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Development of novel beta-amyloid probes based on 3, 5-diphenyl-l, 2, 4-oxadiazole2008
- Author(s)
  Ono M, Haratake M, Saji H, et al
- Journal Title
  
  Bioorganic Medicinal Chemistry 16
  
  Pages: 6867-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] Development of novel β-amyloid probes based on 3, 5-diphenyl-1, 2, 4-oxadiazole.2008
- Author(s)
  M. Ono, M. Haratake, H. Saji, M. Nakayama
- Journal Title
  
  Bioorganic & Medicinal Chemistry 16
  
  Pages: 6867-6872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Development of novel β-amyloid probes based on 3, 5-diphenyl-1, 2, 4-oxadiazole2008
- Author(s)
  M. Ono, M. Haratake, H. Saji, M. Nakayama
- Journal Title
  
  Bioorganic & Medicinal Chemistry 16
  
  Pages: 6867-6872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Novel chalcones as probes for in vivo imaging of β-amyloid plaques in Alzheimer's brains2007
- Author(s)
  M. Ono, M. Haratake, H. Mori, M. Nakayama
- Journal Title
  
  Bioorganic and Medicinal Chemistry 15
  
  Pages: 6802-6809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] urones serve as probes of β-amyloid plaques in Alzheimer's disease2007
- Author(s)
  Ono M, Maya Y, Haratake M, Ito K, Mori H, Nakayama M
- Journal Title
  
  Biochemical and Biophysical Research Communications 361
  
  Pages: 116-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Structure-activity relationship of chalcones and related derivatives as ligands for detecting of beta-amyloid plaques2007
- Author(s)
  Ono M, et. al.
- Journal Title
  
  Bioorganic & Medicinal Chemistry 15
  
  Pages: 6388-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790896
[Journal Article] Structure-activity relationship of chalcones and related derivatives as ligands for detecting of β-amyloid plaques in the brain2007
- Author(s)
  Ono M, Hori M, Haratake M, Tomiyama T, Mori H, Nakayama M
- Journal Title
  
  Bioorganic and Medicinal Chemistry 15
  
  Pages: 6388-6396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Aurones serve as probes of beta-amyloid plaques in Alzheimer's disease.2007
- Author(s)
  Ono M., et. al.
- Journal Title
  
  Biochem Biophys Res Commun. 361
  
  Pages: 116-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] Novel chalcones as probes for in vivo imaging of β-amyloid plaques in Alzheimer's brains2007
- Author(s)
  Ono M, Haratake M, Mori H, Nakayama M
- Journal Title
  
  Bioorganic and Medicinal Chemistry 15
  
  Pages: 6802-6809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659353
[Journal Article] Structure-activity relationship of chalcones and related derivatives as ligands for detecting of β-amyloid plaques in the brain2007
- Author(s)
  M. Ono, M. Hori, M. Haratake, T. Tomiyama, H. Mor, M. Nakayama
- Journal Title
  
  Bioorganic and Medicinal Chemistry 15
  
  Pages: 6388-6396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Novel chalcones as probes for in vivo imaging of β-amyloid plaques in Alzheimer's brainis2007
- Author(s)
  Ono M, Haratake M, Mori H, Nakayama M
- Journal Title
  
  Bioorganic and Medicinal Chemistry 15
  
  Pages: 6802-6809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Structure-activity relationship of chalcones and related derivatives as ligands for detecting of beta-amyloid2007
- Author(s)
  Ono M., et. al.
- Journal Title
  
  Bioorg Med Chem. 15
  
  Pages: 6388-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] Aurones serve as probes of β-amyloid plaques in Alzheimer's disease2007
- Author(s)
  M. Ono, Y. Maya, M. Haratake, K. Ito, H. Mori, M. Nakayama
- Journal Title
  
  Biochemical and Biophysical Research Communications 361
  
  Pages: 116-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390015
[Journal Article] Structure-activity relationship of chalcones and related derivatives as ligands for detecting of β-amyloid plaques in the brain2007
- Author(s)
  Ono M, Hori M, Haratake M, Tomiyama T, Mori H, Nakayama M
- Journal Title
  
  Bioorganic and Medicinal Chemistry 15
  
  Pages: 6388-6396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659353
[Journal Article] Aurones serve as probes of β-amyloid plaques in Alzheimer's disease2007
- Author(s)
  Ono M, Maya Y, Haratake M, Ito K, Mori H, Nakayama M
- Journal Title
  
  Biochemical and Biophysical Research Communications 361
  
  Pages: 116-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659353
[Journal Article] Novel chalcones as probes for in vivo imaging of beta-amyloid plaques in Alzheimer's brains.2007
- Author(s)
  Ono M., et. al.
- Journal Title
  
  Bioorg Med Chem. 15
  
  Pages: 6802-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] Synthesis and biological evaluation of (E)-3-styrylpyridine derivatives as amyloid imaging agents for Alzheimer's disease2005
- Author(s)
  Ono M, Haratake M, Nakayama M, Kaneko, Y, Kawabata K, Mori H, Kung MP, Kung HF.
- Journal Title
  
  Nuclear Medicine and Biology 32(4)
  
  Pages: 329-335
- Data Source
  KAKENHI-PROJECT-16790734
[Journal Article] Radioiodinated flavones for in vivo imaging of β-amyloid plaques in the brain.2005
- Author(s)
  M.Ono, N.Yoshida, K.Ishibashi, M.Haratake, Y.Arano, H.Mori, M.Nakayama
- Journal Title
  
  J.Med.Chem, 48(23)
  
  Pages: 7253-7260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Development of a Rhenium-186-labeled MAG_3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals2005
- Author(s)
  K.Ogawa, T.Mukai, Y.Arano, M.Ono, H.Hanaoka, S.Ishino, K.Hashimoto, H.Nishimura, H.Saji
- Journal Title
  
  Bioconjugate Chem. 16・4
  
  Pages: 751-757
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Radioiodinated flavones for in vivo imaging of β-amyloid plaques in the brain.2005
- Author(s)
  M.Ono, N.Yoshida, K.Ishibashi, M.Haratake, Y.Arano, H.Mori, M.Nakayama
- Journal Title
  
  J.Med.Chem 48・23
  
  Pages: 7253-7260
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Development of a Rhenium-186-labeled MAG_3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals2005
- Author(s)
  K.Ogawa, T.Mukai, Y.Arano, M.Ono, H.Hanaoka, S.Ishino, K.Hashimoto, H.Nishimura, H.Saji
- Journal Title
  
  Bioconjugate Chem., 16(4)
  
  Pages: 751-757
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Synthesis and biological evaluation of (E)-3-styrylpyridine derives as amyloid imaging agents for Alzheimer's disease.2005
- Author(s)
  M.Ono, M.Hatarake, M.Nakayama, K.Kawabata, H.Mori, M-P.Kung, H.F.Kung
- Journal Title
  
  Nucl.Med.Biol 32・4
  
  Pages: 329-335
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Radioiodinated flavones for in vivo imaging of β-amyloid plaques in the brain.2005
- Author(s)
  M.Ono, N.Yoshida, K.Ishibashi, M.Haratake, Y.Arano, H.Mori, M.Nakayama
- Journal Title
  
  J.Med.Chem. 48・23
  
  Pages: 7253-7260
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain.2005
- Author(s)
  Ono M, Yoshida N, Ishibashi K, Haratake M, Alano Y, Mori H, Nakayama M.
- Journal Title
  
  Journal of Medicinal Chemistry 48(23)
  
  Pages: 7253-7260
- Data Source
  KAKENHI-PROJECT-16790734
[Journal Article] Synthesis and biological evaluation of (E)-3-styrylpyridine derivatives as amyloid imaging agents for Alzheimer's disease.2005
- Author(s)
  M.Ono, M.Haratake, M.Nakayama, K.Kawabata, H.Mori, M-P.Kung, H.F.Kung
- Journal Title
  
  Nucl.Med.Biol., 32(4)
  
  Pages: 329-335
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Synthesis and biological evaluation of (E)-3-styrylpyridine derivatives as amyloid imaging agents for Alzheimer's disease.2005
- Author(s)
  M.Ono, M.Haratake, M.Nakayama, K.Kawabata, H.Mori, Mei-Ping Kung, Hank F.Kung
- Journal Title
  
  Nucl.Med.Biol. 32・4
  
  Pages: 329-335
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] ^<11>C-labeled stilbene derivatives as Aβ-aggregate-specific PET imaging agents for Alzheimer's disease.2003
- Author(s)
  M.Ono, A.Wilson, J.Nobrega, D.Westaway, P.Verhoeff, Zhi-Ping Zhuang, M-P.Kung, H.F.Kung
- Journal Title
  
  Nucl.Med.Biol., 30(6)
  
  Pages: 565-571
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] A new ^<68>Ge/^<68>Ga generator system using an organic polymer containing N-methylglucamine groups as adsorbent for ^<63>Ge.2003
- Author(s)
  M.Nakayama, M.haratake, M.Ono, T.Koiso, K.Harada, H.Nakayama, S.Yahara, M.Nakayama, Y.Arano
- Journal Title
  
  Appl. red. Isotope. 58・1
  
  Pages: 9-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] A new ^<68>Ge/^<68>Ga generator system using an organic polymer containing N-methylglucamine groups as adsorbent for ^<68>Ge.2003
- Author(s)
  M.Nakayama, M.Haratake, M.Ono, T.Koiso, K.Harada, H.Nakayama, S.Yahara, Y.Ohmomo, Y.Arano
- Journal Title
  
  Appl.Rad.Isotope., 58(1)
  
  Pages: 9-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] A new hydroxamamide-based ligand system for Tc^^99m labeling for proteine and peptides2003
- Author(s)
  M.Nakayama, M.Ono, M.haratake
- Journal Title
  
  Biomedical Research on Trance Elements 14・1
  
  Pages: 29-33
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] ^<11>C-labeled stilbene derivatives as Aβ-aggregate-specific PET imaging agents for Alzheimer's disease.2003
- Author(s)
  M.Ono, A.Wilson, J.Nobrega, D.Westaway, P.Verhoeff, Zhi-Ping Zhuang, M-P.Kung, H.F.kung
- Journal Title
  
  Nucl. Med. Biol 30・6
  
  Pages: 565-571
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] A new hydroxamamide-based ligand system for ^<98m>Tc labeling for proteine and peptides2003
- Author(s)
  M.Nakayama, M.Ono, M.Haratake
- Journal Title
  
  Biomedical Research on Trace Elements, 14(1)
  
  Pages: 29-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Synthesis and Biological Evaluation of (E)-3-Styrylpyridine Derivatives as Amyloid Imaging Agents for Alzheimer's Disease
- Author(s)
  Masahiro Ono et al.
- Journal Title
  
  Nuclear Medicine and Biology (印刷中)
- Data Source
  KAKENHI-PROJECT-16790734
[Journal Article] Novel ^<18>F-labeled benzofuran derivatives with improved properties for PET imaging of ￡]-amyloid plaques in Alzheimer's brains.
- Author(s)
  Ono M, Cheng Y, Kimura H, Cui MC, Kagawa S, Nishii R, Saji H.
- Journal Title
  
  Journal of Medicinal Chemistry in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Novel design and synthesis of a radioiodinated glycolipid analog as an acceptor substrate for N-acetylglucosaminyltransferase V
- Author(s)
  Kenji Arimitsu, Hiroyuki Kimura, Tetsuya Kajimoto, Masahiro Ono, Yoshiro Ohmomo, Masayuki Yamashita, Manabu Node, and Hideo Saji
- Journal Title
  
  Journal of Labelled Compounds and Radiopharmaceuticals
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046
[Journal Article] Novel benzofuran derivatives for PET imaging of β-amyloid plaques in Alzheimer's disease brains.
- Author(s)
  M.Ono, H.Kawasaki, A.Nonaka, T.Kawai, M.Haratake, H.Mori, M-P.kung, H.F.Kung, H.Saji, M.Nakayama
- Journal Title
  
  J.Med.Chem (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains.
- Author(s)
  Ono M, Hayashi S, Matsumura K, Kimura H, Okamoto Y, Ihara M, Takahashi R, Mori H, Saji H.
- Journal Title
  
  ACS Chemical Neuroscience in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] SPECT imaging agents for detecting cerebral β-amyloid plaques.
- Author(s)
  Ono M, Saji H.
- Journal Title
  
  International Journal of Molecular Imaging in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Phenyldiazenyl benzothiazole derivatives as probes for in vivo imaging of neurofibrillary tangles in Alzheimer's disease brains.
- Author(s)
  Matsumura K, Ono M, Hayashi S, Kimura H, Okamoto Y, Ihara M, Takahashi R, Mori H, Saji H.
- Journal Title
  
  Medicinal Chemistry Communications in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Synthesis and Biological Evaluation of (E)-3-Styrylpyridine Derivatives as Amyloid Imaging Agents for Alzheimer's Disease
- Author(s)
  Masahiro Ono et al.
- Journal Title
  
  Nuclear Medicine and Biology (印刷中)
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Molecular Imaging of β-Amyloid Plaques with Near-Infrared BODIPY-based Fluorescent Probes
- Author(s)
  Hiroyuki Watanabe, Masahiro Ono, Kenji Matsumura, Masashi Yoshimura, Hiroyuki Kimura, Hideo Saji
- Journal Title
  
  Molecular Imaging
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046
[Journal Article] Synthesis and structure-affinity relationships of novel dibenzylideneacetone derivatives as probes for β-amyloid plaques.Journal of Medicinal Chemistry
- Author(s)
  Cui MC, Ono M, Kimura H, Liu BL, Saji H.
- Journal Title
  
  (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Journal Article] Novel benzofuran derivatives for PET imaging of β-amyloid plaques in Alzheimer's disease brains.
- Author(s)
  M.Ono, H.Kawashima, A.Nonaka, T.Kawai, M.Haratake, H.Mori, M-P.Kung, H.F.Kung, H.Saji, M.Nakayama
- Journal Title
  
  J.Med.Chem., (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Journal Article] Radioiodinated Benzimidazole Derivatives as Single Photon Emission Computed Tomography Probes for Imaging of β-Amyloid Plaques in Alzheimer's Disease
- Author(s)
  Cui M, Ono M, Kimura H, Kawashima H, Liu BL, Saji H.
- Journal Title
  
  Nuclear Medicine and Biology in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689023
[Patent] 放射性ハロゲン標識ピリド[1,2-a]ベンゾイミダゾール誘導体化合物2015
- Inventor(s)
  小野正博、佐治英郎、猪原匡史、松本博樹、関育也
- Industrial Property Rights Holder
  小野正博、佐治英郎、猪原匡史、松本博樹、関育也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-161472
- Filing Date
  2015-08-19
- Data Source
  KAKENHI-PROJECT-15H04271
[Patent] コンフォメーション病診断用組成物2010
- Inventor(s)
  佐治英郎、小野正博
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2010-04-12
- Overseas
- Data Source
  KAKENHI-PROJECT-20689023
[Patent] ベンゾチアゾール誘導体含有診断用組成物2009
- Inventor(s)
  佐治英郎, 小野正博, 河嶋秀和, 木村寛之
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-037773
- Filing Date
  2009-02-20
- Data Source
  KAKENHI-PROJECT-19209041
[Patent] コンフォメーション病診断のための組成物2009
- Inventor(s)
  佐治英郎、小野正博
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-107457
- Filing Date
  2009-04-27
- Data Source
  KAKENHI-PROJECT-20689023
[Patent] コンフォメーション病診断用組成物2009
- Inventor(s)
  佐治英郎、小野正博
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-107457
- Filing Date
  2009-04-27
- Data Source
  KAKENHI-PROJECT-20689023
[Patent] コンフォメーション病診断のための組成物2009
- Inventor(s)
  佐治英郎、小野正博, 他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-222156
- Filing Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-19209041
[Patent] コンフォメーション病診断用組成物2009
- Inventor(s)
  佐治英郎、小野正博
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-107457
- Acquisition Date
  2009-04-27
- Data Source
  KAKENHI-PROJECT-19209041
[Patent] コンフォメーション病診断のための組成物2009
- Inventor(s)
  佐治英郎、小野正博、木村寛之、河嶋秀和
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-222156
- Acquisition Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-19209041
[Patent] コンフォメーション病診断用組成物2009
- Inventor(s)
  佐治英郎、小野正博
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-222156
- Filing Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-20689023
[Patent] アゼチジニルメトキシピリミジン誘導体の製造法及びその使用2009
- Inventor(s)
  佐治英郎、木村寛之、小野正博、河嶋秀和、森大輔、原田直弥
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-228646
- Acquisition Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-19209041
[Patent] プリオン病診断用組成物2007
- Inventor(s)
  中山守雄、原武衛、小野正博、片峰茂、西田教行
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2007-316987
- Filing Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-18659353
[Patent] アミロイド関連疾患診断用組成物2005
- Inventor(s)
  中山守雄, 原武衛, 小野正博, 森啓
- Industrial Property Rights Holder
  長崎大学
- Filing Date
  2005-11-25
- Data Source
  KAKENHI-PROJECT-15390014
[Patent] アミロイド関連疾患診断用組成物2005
- Inventor(s)
  中山守雄, 原武衛, 小野正博, 森啓
- Industrial Property Rights Holder
  長崎大学
- Filing Date
  2005-11-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Patent] アミロイド関連疾患診断用組成物2004
- Inventor(s)
  中山守雄, 原武衛, 小野正博, 森啓
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2004-341370
- Filing Date
  2004-11-26
- Data Source
  KAKENHI-PROJECT-16790734
[Patent] アミロイド関連疾患診断用組成物2004
- Inventor(s)
  中山守雄, 原武衛, 小野正博, 森啓
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2004-341370
- Filing Date
  2004-11-26
- Data Source
  KAKENHI-PROJECT-15390014
[Patent] アミロイド関連疾患診断用組成物2004
- Inventor(s)
  中山守雄, 原武衛, 小野正博, 森啓
- Industrial Property Rights Holder
  長崎大学
- Industrial Property Number
  2004-341370
- Filing Date
  2004-11-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390014
[Presentation] Aβオリゴマー標的近赤外蛍光プローブとしてのチオフェン置換BODIPY誘導体の合成と評価2024
- Author(s)
  赤坂貴浩, 渡邊裕之, 小野正博
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K19490
[Presentation] アミロイドβオリゴマーを標的とした新規近赤外蛍光イメージング法の開発2023
- Author(s)
  赤坂貴浩, 渡邊裕之, 小野正博
- Organizer
  第20回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-22K19490
[Presentation] アミロイドPET薬剤開発の過去・現在・未来2023
- Author(s)
  小野正博
- Organizer
  第４回日本核医学会関東甲信越支部会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19490
[Presentation] In vivo near-infrared imaging targeting amyloid β oligomers in model mouse of Alzheimers disease2023
- Author(s)
  Takahiro Akasaka, Hiroyuki Watanabe, Masahiro Ono
- Organizer
  京都大学第3回研究交流サロン
- Data Source
  KAKENHI-PROJECT-22K19490
[Presentation] AβオリゴマーイメージングプローブとしてのBODIPY誘導体の有用性評価2023
- Author(s)
  赤坂貴浩, 渡邊裕之, 小野正博
- Organizer
  第17回日本分子イメージング学会
- Data Source
  KAKENHI-PROJECT-22K19490
[Presentation] アミロイドイメージング剤の開発における薬学的貢献2022
- Author(s)
  小野正博
- Organizer
  第42回日本核医学技術学会総会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] αシヌクレインイメージングプローブの開発を目的とした放射性ヨウ素標識オーロン誘導体の合成と評価2021
- Author(s)
  赤坂貴浩, 渡邊裕之, 貝出翔, 飯國慎平, 小野正博
- Organizer
  第18回次世代を担う若手のためのフィジカル・ファーマフォーラム (仙台)
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] αシヌクレインイメージングプローブの開発を目的とした新規18F標識スチリルキノリン/キノキサリン誘導体の合成と評価2021
- Author(s)
  中川航平, 渡邊裕之, 貝出翔, 飯國慎平, 志水陽一, 小野正博
- Organizer
  第4回日本核医学会分科会放射性薬品科学研究会/第19回放射性医薬品・画像診断薬研究会（仙台)
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] カルコン類縁体を基盤としたαシヌクレイン標的PETイメージングプローブの開発2021
- Author(s)
  貝出翔, 渡邊裕之, 飯國慎平, 志水陽一, 長谷川成人, 伊東恭子, 小野正博
- Organizer
  第61回日本核医学会学術総会（名古屋）
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] 脳タンパク質凝集体の生体イメージング技術2021
- Author(s)
  小野正博
- Organizer
  第40回日本認知症学会学術総会（東京）
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] 神経変性疾患における脳タンパク質凝集体を標的とした核医学イメージング法の開発2021
- Author(s)
  貝出翔, 渡邊裕之, 飯國慎平, 小野正博
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] αシヌクレインの生体イメージングを目的とした放射性ヨウ素標識スチリルキノキサリン誘導体の合成および評価2021
- Author(s)
  中川航平, 渡邊裕之, 貝出翔, 飯國慎平, 長谷川成人, 伊東恭子, 小野正博
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] αシヌクレインの生体イメージングを目的としたビスキノリン誘導体の合成および評価2019
- Author(s)
  貝出翔, 渡邊裕之, 志水陽一, 飯國慎平, 長谷川成人, 伊東恭子, 小野正博
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H04260
[Presentation] ベンゾイミダゾピリジン骨格を基盤とする新規PET用タウイメージングプローブの開発2018
- Author(s)
  貝出翔, 渡邊裕之, 辰巳悠華, 志水陽一, 佐治英郎, 小野正博
- Organizer
  第58回日本核医学会学術総会
- Data Source
  KAKENHI-PUBLICLY-17H05694
[Presentation] タウの生体イメージングを目的としたSPECTプローブの開発2018
- Author(s)
  貝出翔，渡邊裕之，志水陽一，佐治英郎，小野正博
- Organizer
  2018 タウ研究ミーティング
- Data Source
  KAKENHI-PUBLICLY-17H05694
[Presentation] アルツハイマー病脳内タウを標的とした放射性ヨウ素標識ベンゾイミダゾピリジン誘導体に関する構造活性相関研究2017
- Author(s)
  貝出翔, 小野正博, 渡邊裕之, 志水陽一, 佐治英郎
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PUBLICLY-17H05694
[Presentation] アルツハイマー病脳内タウのSPECTイメージングを目的とした新規123I標識ベンゾイミダゾピリジン誘導体の開発2017
- Author(s)
  貝出翔, 小野正博, 北田彩音, 吉村優志, 渡邊裕之, 佐治英郎
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PUBLICLY-15H01555
[Presentation] αシヌクレインイメージングプローブの開発を目的とした新規ベンゾイミダゾール誘導体の合成と評価2017
- Author(s)
  有吉泰亮, 渡邊裕之, 小野正博, 佐治英郎
- Organizer
  第12回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17H04260
[Presentation] 新規白質プローブ18F-PQ6を用いた多発性硬化症モデルマウスのインビボPET/MRI病態解析2016
- Author(s)
  天滿　敬、圓見純一郎、平瀬　僚、白川久志、吉村優志、小野正博、金子周司、佐治英郎、飯田秀博
- Organizer
  第56回日本核医学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K09912
[Presentation] 多価99mTc錯体を用いる脳アミロイドアンギオパチーの核医学イメージング2016
- Author(s)
  小野正博
- Organizer
  日本核医学会
- Place of Presentation
  名古屋
- Year and Date
  2016-11-03
- Invited
- Data Source
  KAKENHI-PROJECT-26293274
[Presentation] 腫瘍の高感度光音響イメージングを目的としたインドシアニングリーン多点結合ポリオキサゾリンの開発研究2016
- Author(s)
  佐野紘平, 金崎健吾, 牧野顕, 小野正博, 佐治英郎
- Organizer
  第11回日本分子イメージング学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-15H04637
[Presentation] 脳アミロイドアンギオパチーイメージングを目的とした新規2価99mTc錯体の合成と評価2015
- Author(s)
  飯國慎平, 小野正博, 渡邊裕之, 木村寛之, 佐治英郎
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26293274
[Presentation] Novel tau-SPECT imaging agents based on pyrido[1,2-a]benzoimidazole scaffold2015
- Author(s)
  Masahiro Ono, Kenji Matsumura, Hiroyuki Watanabe, Hiroyuki Kimura, Hideo Saji
- Organizer
  Society of Nuclear Medicine and Molecular Imaging 2015 Annual Meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01555
[Presentation] インドシアニングリーン結合ポリエチレングリコールを母体とした腫瘍診断用光音響プローブの開発2015
- Author(s)
  金崎健吾, 佐野紘平, 牧野顕, 小野正博, 佐治英郎
- Organizer
  第15回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15H04637
[Presentation] 腫瘍発現分子のインビボ磁気共鳴/光音響デュアルイメージングを目指した酸化鉄粒子を基盤とする分子プローブの創製2015
- Author(s)
  佐野紘平, 金崎健吾, 丁寧, 小野正博, 佐治英郎
- Organizer
  第65回日本薬学会近畿支部総会・大会
- Place of Presentation
  富田林
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15H04637
[Presentation] Development of polyethylene glycol conjugated with indocyanine green as a photoacoustic tumor imaging probe2015
- Author(s)
  Kohei Sano, Kengo Kanazaki, Akira Makino, Atsushi Takahashi, Fumio Yamauchi, Tsutomu Homma, Hiroyuki Watanabe, Takashi Temma, Masahiro Ono, Hideo Saji
- Organizer
  World Molecular Imaging Congress 2015
- Place of Presentation
  Honolulu
- Year and Date
  2015-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04637
[Presentation] SPECT 用タウイメージングプローブの開発を目的としたベンゾイミダゾピリジン誘導体の合成と評価2015
- Author(s)
  北田彩音, 小野正博, 渡邊裕之, 佐治英郎
- Organizer
  第13回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  長崎
- Year and Date
  2015-08-20
- Data Source
  KAKENHI-PUBLICLY-15H01555
[Presentation] Insulinoma イメージングを目的とした In-111 標識 Exendin(9-39)誘導体の開発2012
- Author(s)
  松田洋和, 木村寛之,小川祐, 豊田健太郎,高木美佳子,今麻実, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Development of 123I-labeled Exendin derivative binding to GLP-1 receptors for imaging insulinoma by SPECT2012
- Author(s)
  H. Matsuda, H. Kimura, Y. Ogawa, M. Takagi, A. Kon, M. Ono, K. Toyoda, N. Inagaki, H. Saji
- Organizer
  Society of Nuclear Medicine 59th Annual Meeting
- Place of Presentation
  Miami beach
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Insulinoma の核医学イメージングのための GLP-1R 標的[123I]Exendin(9-39)誘導体の開発2012
- Author(s)
  松田洋和, 木村寛之,小川祐, 豊田健太郎, 高木美佳子, 今麻実, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第7回日本分子イメージング学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Insulinomaの核医学イメージングのためのGLP-1R標的[123I]Exendin(9-39)誘導体の開発2012
- Author(s)
  松田洋和, 木村寛之,小川祐, 豊田健太郎, 高木美佳子, 今麻実, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第7回日本分子イメージング学会
- Place of Presentation
  アクトシティ浜松（静岡県）
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Development of 123I-labeled Exendin derivative binding to GLP-1 receptors for imaging insulinoma by SPECT2012
- Author(s)
  H. Matsuda, H. Kimura, Y. Ogawa, M. Takagi, A. Kon, M. Ono, K. Toyoda, N. Inagaki, H. Saji
- Organizer
  Society of Nuclear Medicine 59th Annual Meeting
- Place of Presentation
  Miami beach, USA
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 膵β細胞 GLP-1 受容体を標的とする PET 用イメージングプローブとしての18^F 標識 Exendin-4 誘導体の開発2012
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎,向英理, 藤本裕之, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] タウ結合性化合物の探索とその分子イメージングプローブへの応用2011
- Author(s)
  松村憲志、小野正博、林瞬、木村寛之、岡本洋子、猪原匡史、高橋良輔、佐治英郎
- Organizer
  第131回日本薬学会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] Synthesis and evaluation of radioiodinated exendin derivatives for the imaging of GLP-1 receptor expression in pancreatic islets2011
- Author(s)
  Kimura H, Ogawa Y, Kawashima H, Mukai E, Toyoda K, Fujimoto H, Hirao K, Ono M, Inagaki N, Saji H
- Organizer
  Society of Nuclear Medicine 57th Annual Meeting
- Place of Presentation
  Salt Lake City
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] タウ結合性化合物の探索とその分子イメージングプローブへの応用2011
- Author(s)
  松村憲志、小野正博、林瞬、木村寛之、岡本洋子、猪原匡史、高橋良輔、佐治英郎
- Organizer
  第131年会日本薬学会
- Place of Presentation
  静岡コンベンションアーツセンター(静岡)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] 膵β細胞 GLP-1 受容体標的放射性プローブとしての I-123 標識Exendin-4 誘導体2011
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎,向英理, 藤本裕之, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第9回次世代を担う若手のためのフィジカル・ファーマフォーラム(PPF2011)
- Place of Presentation
  箱根
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] スルホニル尿素受容体 SUR1 を標的とした膵β細胞イメージング用放射性分子プローブの開発2011
- Author(s)
  松田洋和,木村寛之,小川祐,豊田健太郎,向英里,藤本裕之,中村博,平尾佳,小野正博,稲垣暢也,佐治英郎
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] スルホニル尿素受容体SUR1を標的とした膵β細胞イメージング用放射性分子プローブの開発2011
- Author(s)
  松田洋和、木村寛之、小川祐、豊田健太郎、向英里、藤本裕之、中村博、平尾佳、小野正博、稲垣暢也、佐治英郎
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市、グランシップ
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 膵β細胞 GLP-1受容体を標的とする SPECT 用イメージングプローブの開発2011
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎, 向英里, 藤本裕之, 平尾佳, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Auroneを母核とする新規^<18>F標識Aβイメージングプローブの開発2011
- Author(s)
  程妍、小野正博、木村寛之、上田真史、中本裕士、富樫かおり、中山守雄、佐治英郎
- Organizer
  第131回日本薬学会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] 膵β細胞GLP-1受容体を標的とするSPECT用イメージングプローブの開発2011
- Author(s)
  小川祐、木村寛之、河嶋秀和、豊田健太郎、向英里、藤本裕之、平尾佳、松田洋和、小野正博、稲垣暢也、佐治英郎
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市、グランシップ
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 膵β細胞 GLP-1 受容体を標的とする SPECT 用イメージングプローブ Exendin(9-39)誘導体の開発2011
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎,向英理, 藤本裕之, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第51回日本核医学会学術総会
- Place of Presentation
  筑波
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Auroneを母核とする新規^<18>F標識Aβイメージングプローブの開発2011
- Author(s)
  程妍、小野正博、木村寛之、上田真史、中本裕士、富樫かおり、中山守雄、佐治英郎
- Organizer
  第131年会日本薬学会
- Place of Presentation
  静岡コンベンションアーツセンター(静岡)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] βアミロイドタンパク質の生体イメージングを目的とした近赤外蛍光プローブの開発2011
- Author(s)
  渡邊裕之、小野正博、松村憲志、木村寛之、佐治英郎
- Organizer
  第131年会日本薬学会
- Place of Presentation
  静岡県コンベンションアーツセンター(静岡)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21659288
[Presentation] ^<18>F Labeled Benzofuran Derivatives as PET Probes for Detection of β-Amyloid Plaques2010
- Author(s)
  程妍、小野正博、木村寛之、加川信也、西井龍一、佐治英郎
- Organizer
  第50回日本核医学会
- Place of Presentation
  大宮
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] ^<18>F Labeled Benzofuran Derivatives as PET Probes for Detection of β-Amyloid Plaques2010
- Author(s)
  程妍、小野正博、木村寛之、加川信也、西井龍一、佐治英郎
- Organizer
  第50回核医学会
- Place of Presentation
  大宮ソニックシティ(大宮)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] Fluorinated Benzofuran Derivatives for PET Imaging of β-Amyloid Plaques in Alzheimer's Disease Brains2010
- Author(s)
  Yan Cheng, Masahiro Ono, Hiroyuki Kimura, Shinya Kagawa, Ryuichi Nishii, Hidekazu Kawashima, Hideo Saji
- Organizer
  World Molecular Imaging Congress
- Place of Presentation
  京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] タウ結合性化合物の探索とその分子イメージングプローブへの応用2010
- Author(s)
  松村憲志、小野正博、林瞬、木村寛之、岡本洋子、猪原匡史、高橋良輔、佐治英郎
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] SUR1受容体を標的とした膵β細胞イメージング用放射性プローブの開発2010
- Author(s)
  松田洋和、木村寛之、小川祐、河嶋秀和、豊田健太郎、向英里、藤本裕之、平尾佳、小野正博、稲垣暢也、佐治英郎
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  さいたま市、大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] βアミロイドの分子イメージングを目的としたPET/SPECTプローブの開発2010
- Author(s)
  小野正博
- Organizer
  日本薬理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] Synthesis and evaluation of radioiodinated exendin derivatives for the imaging of GLP-1 receptor expression in pancreatic islets.2010
- Author(s)
  Kimura H, Ogawa Y, Kawashima H, Mukai E, Toyoda K, Fujimoto H, Hirao K, Ono M, Inagaki N, Saji H
- Organizer
  Society of Nuclear Medicine 57^<th> Annual Meeting
- Place of Presentation
  Salt Lake City, USA
- Year and Date
  2010-06-08
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] タウ結合性化合物の探索とその分子イメージングプローブへの応用2010
- Author(s)
  松村憲志、小野正博、林瞬、木村寛之、岡本洋子、猪原匡史、高橋良輔、佐治英郎
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都テルサ京都府民総合交流プラザ(京都)
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] Fluorinated Benzofuran Derivatives for PET Imaging of β-Amyloid Plaques in Alzheimer's Disease Brains2010
- Author(s)
  Yan Cheng, Masahiro Ono, Hiroyuki Kimura, Shinya Kagawa, Ryuichi Nishii, Hidekazu Kawashima, Hideo Saji
- Organizer
  World Molecular Imaging Congress
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] βアミロイドのPET/SPECT分子イメージングプローブの開発(次世代の薬効評価系を目指した新しい光学技術)2010
- Author(s)
  小野正博
- Organizer
  日本薬理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] アルツハイマー病診断を目的とした新規タウイメージングプローブの開発2010
- Author(s)
  松村憲志、小野正博、林瞬、木村寛之、岡本洋子、猪原匡史、高橋良輔、佐治英郎
- Organizer
  第50回日本核医学会
- Place of Presentation
  大宮
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] GLP-1受容体を標的とする放射性ヨウ素標識イメージングプローブの開発2010
- Author(s)
  小川祐、木村寛之、河嶋秀和、豊田健太郎、向英里、藤本裕之、平尾佳、松田洋和、小野正博、稲垣暢也、佐治英郎
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  さいたま市、大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] オーロンを基本骨格とするPET/SPELTハイブリッド型アミロイドイメージングプローブの開発2010
- Author(s)
  渡邊裕之、小野正博、真矢啓史、淵上剛志、原武衛、佐治英郎、中山守雄
- Organizer
  第5回日本分子イメージング学会
- Place of Presentation
  ピアザ淡海滋賀県立県民交流センター(滋賀)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21659288
[Presentation] アルツハイマー病診断を目的とした新規タウイメージングプローブの開発2010
- Author(s)
  林瞬、小野正博、松村憲志、木村寛之、河嶋秀和、佐治英郎
- Organizer
  第50回核医学会
- Place of Presentation
  大宮ソニックシティ(大宮)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] SUR1 受容体を標的とした膵β細胞イメージング用放射性プローブの開発2010
- Author(s)
  松田洋和, 木村寛之, 小川祐, 河嶋秀和, 豊田健太郎, 向英里, 藤本裕之, 平尾佳, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] GLP-1 受容体を標的とする放射性ヨウ素標識イメージングプローブの開発2010
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎, 向英里, 藤本裕之, 平尾佳, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 多機能性βアミロイドイメージングプローブの開発を目的としたベンゾチアソール誘導体の合成と評価2009
- Author(s)
  林瞬, 小野正博, 木村寛之, 河嶋秀和, 中山守雄, 佐治英郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] アルツハイマー病脳内βアミロイド蛋白を標的としたインビボ蛍光イメージングフローブの開発2009
- Author(s)
  石川真奈美, 小野正博, ら
- Organizer
  日本分子イメージング学会
- Place of Presentation
  東京
- Year and Date
  2009-05-14
- Data Source
  KAKENHI-PROJECT-21659288
[Presentation] アミロイドイメージングの基礎2009
- Author(s)
  小野正博
- Organizer
  第49回日本核医学会
- Place of Presentation
  旭川
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20689023
[Presentation] βアミロイドデュアルイメージングプローブの開発を目的としたBODIPY誘導体の合成と評価2009
- Author(s)
  石川真奈美、小野正博、木村寛之, 他
- Organizer
  第49回日本核医学会学術総会
- Place of Presentation
  旭川グランドホテル(旭川)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] アルツハイマー病脳内βアミロイド蛋白を標的としたインビボ蛍光イメージングプローブの開発2009
- Author(s)
  石川真奈美、小野正博、木村寛之, 他
- Organizer
  第4回日本分子イメージング学会学術集会
- Place of Presentation
  学術総合センター(東京)
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] アルツハイマー病における脳内β-セクレターゼイメージングを目的としたhydroxyethylamine dipeptide isoster誘導体の合成と評価2009
- Author(s)
  河合知喜, 河嶋秀和, 木村寛之, 小野正博, 佐治英郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] [^<11>C]Galanthamineの合成と脳内分布評価2009
- Author(s)
  小川祐, 河合知喜, 木村寛之, 河嶋秀和, 濱島好男, 野出學, 小野正博, 佐治英郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] プリオン病診断を目的とした異常型プリオン蛋白イメージングプローブの探索2008
- Author(s)
  祖母井香織, 小野正博, 新竜一郎, 西田教行, 片峰茂, 河嶋秀和, 佐治英郎, 清野泰, 藤林靖久, 原武衛, 中山守雄
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パジフィコ横浜会議センター
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18659353
[Presentation] N-メチルグルカミン型樹脂を用いる^<68>Ge/^<68>Gaジェネレータの開発と応用2007
- Author(s)
  畠中瑛介, 原武衛, 小野正博, 中山守雄, 五十嵐隆
- Organizer
  1
- Place of Presentation
  仙台市国際センター
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-18390015
[Presentation] N-メチルグルカミン型樹脂を用いる^<68>Ge/^<68>Gaジェネレータの開発と応用2007
- Author(s)
  畠中瑛介、原武衛、小野正博、中山守雄、五十嵐隆
- Organizer
  第47回日本核医学会学術総会
- Place of Presentation
  仙台市
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-18390015
[Presentation] Insulinomaイメージングを目的としたIn-111標識Exendin(9-39)誘導体の開発
- Author(s)
  松田洋和, 木村寛之,小川祐, 豊田健太郎, 高木美佳子, 今麻実, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都テルサ(京都府）
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 脳アミロイドアンギオパチーの核医学分子イメージングを目的とした99mTc 標識ベンゾチアゾール誘導体の開発
- Author(s)
  飯國慎平, 小野正博, 渡邊裕之, 木村寛之, 佐治英郎
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293274
[Presentation] 脳アミロイドアンギオパチーの核医学イメージングを目的とした2価99mTc錯体の開発
- Author(s)
  飯國慎平、小野正博、渡邊裕之、木村寛之、佐治英郎
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2014-11-06 – 2014-11-08
- Data Source
  KAKENHI-PROJECT-26293274
[Presentation] 2 価 99mTc 錯体を用いた脳アミロイドアンギオパチーの生体イメージング
- Author(s)
  飯國慎平、小野正博、渡邊裕之、木村寛之、佐治英郎
- Organizer
  第12回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  箱根
- Year and Date
  2014-07-14 – 2014-07-15
- Data Source
  KAKENHI-PROJECT-26293274

1. SAJI Hideo (40115853)

# of Collaborated Projects: 7 results

# of Collaborated Products: 50 results
2. TEMMA Takashi (90378787)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
3. KITAMURA Hiroyoki (50437240)

# of Collaborated Projects: 6 results

# of Collaborated Products: 34 results
4. NAKAYAMA Morio (60164373)

# of Collaborated Projects: 5 results

# of Collaborated Products: 28 results
5. WATANABE Hiroyuki (40710786)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
6. HARATAKE Mamoru (40325668)

# of Collaborated Projects: 4 results

# of Collaborated Products: 27 results
7. SANO Kohei (00546476)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
8. ARANO Yasushi (90151167)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
9. UEDA Masashi (40381967)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
10. KOJIMA Akihiro (20161903)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KAWASHIMA Hidekazu (70359438)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
12. Kiyono Yasushi (50305603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. IHARA Masafumi (00372590)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 飯田秀博 (30322720)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. 飯國慎平 (70837731)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
16. KUGE Yuji (70321958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. FUKUYAMA Hidenao (90181297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ISHIZU Koichi (50314224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. IRIE Toshiaki (40160072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TOYODA Koichi (00447971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
21. MATSUDA Naoki (00304973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ENMI JUNICHIRO (80393205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. KONDO NAOYA (80756172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TOMIMOTO Hidekazu (80324648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 片峰茂 (40161062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 内木宏延 (10227704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 久米恭 (50359238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 周びん (00598774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 植田初江 (40522983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 志水陽一 (90634212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
31. 花岡宏史 (50361390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 石岡典子 (30354963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. MATSUMURA Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
34. YOSHIMURA Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
35. SAITO Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. YAMAMOTO Yumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. HORIE Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 高橋良輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ono Masahiro 小野 正博

ONO Masahiro 小野 正博

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アルツハイマー病の診断・治療に資する次世代アミロイドβイメージング法の開発Principal Investigator

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神経難病ALSにおけるTDP-43凝集体の生体分子イメージング法の開発Principal Investigator

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Development of nuclear medicine imaging method targeting alfa-synuclein aggregates for diagnosis and treatment of Lewy body disease.Principal Investigator

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Development of amyloid oligomer imaging for early diagnosis of Alzheimer's diseasePrincipal Investigator

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SPECTによるタウイメージング法の開発Principal Investigator

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Development of nuclear medical imaging probes that target alfa-synuclein in Parkinson's diseasePrincipal Investigator

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βアミロイドおよびタウを標的としたSPECTイメージングプローブの開発Principal Investigator

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Development of nuclear medical imaging probes targeting cerebral amyloid antipathyPrincipal Investigator

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Ono Masahiro 小野正博

ONO Masahiro 小野正博