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Naiki Hironobu  内木 宏延

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… Alternative Names

NAIKI Hironobu  内木 宏延

内木 広延  ナイキ ヒロノブ

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Researcher Number 10227704
Other IDs
External Links
Affiliation (Current) 2022: 福井大学, 学術研究院医学系部門, 教授
Affiliation (based on the past Project Information) *help 2016 – 2021: 福井大学, 学術研究院医学系部門, 教授
2003 – 2015: Fukui University, Medical School, Professor, 医学部, 教授
1998 – 2002: 福井医科大学, 医学部, 教授
1995 – 1997: 福井医科大学, 医学部, 助教授
1993 – 1994: 福井医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Biological Sciences / Experimental pathology / Experimental pathology / Science and Engineering / 老化(加齢) / Basic Section 49030:Experimental pathology-related
Except Principal Investigator
Structural biochemistry / Biophysics / Radiation science / Human pathology … More / Experimental pathology / Kidney internal medicine / Laboratory animal science / Neurology / General internal medicine(including psychosomatic medicine) / Kidney internal medicine / Experimental pathology / Biophysics / Neurology / ポストゲノムのナノサイエンス / Basic Section 43020:Structural biochemistry-related / Basic Section 53040:Nephrology-related Less
Keywords
Principal Investigator
アルツハイマー病 / β2-ミクログロブリン / アミロイド線維 / βアミロイド線維 / 透析アミロイド症 / 透析アミロイドーシス / 分子間相互作用 / トランスジェニックマウス / 病理学 / 一次反応速度論モデル … More / 重合核依存性重合モデル / 表面プラズマ共鳴法 / 抗酸化剤 / 変性中間体 / 蛋白質 / アミロイドーシス / チオフラビンT / 分光蛍光定量法 / アミロイド / ベータアミロイド線維 / 立体構造変化 / アミロイド線維分解 / リゾリン脂質 / Aβ蛋白質 / 細胞外シャペロン / C反応性蛋白質 / 細胞傷害 / 血清アミロイドP成分 / 透析アミロイド-シス / アポリポ蛋白E / Alzheimer's disease / apolipoprotein E / 表面プラズモン共鳴法 / 重合速度 / 脱重合速度 / アミロイド線維分解機構 / 原子間力顕微鏡 / チオフラビンT法 / 血管アミロイド症 / アミロイド共存蛋白質 / ベータ2ミクログロブリン / 試験管内形成・分解 / アミロイド共存分子 / 親和性測定 / 体内動態シミュレーション / ポリフェノール化合物 / 線維分解 / ポリフェノール / ビタミンA / 構造活性相関 / 脳神経疾患 / 線維形成・伸長阻害 / フラボノイド / 生体膜模倣環境 / 脂質 / 超音波 / 核形成 / 試験管内分子間相互作用 / トランジェニックマウス / 血清アミロイド成分 / 老化制御 / SPF環境 / 老化促進モデルマウス(SAM) / 免疫機能 / マウス老化アミロイドーシス / Regulation of ageing / Pathogen status / Senescence accelerated mouse (SAM) / Immunological function / Murine senile amyloidosis / βアシロイド線維 / チオフラビン T / beta-amyloid fibril / nucleation-dependent polymerization model / first-order kinetic model / spectrofluorometry / thioflavin T / Aβ蛋白1-42 / 重合核 / βペプチド1-42 / ロジスティック方程式 / β-amyloid fibril / nucleation dependent polymerization model / amyloid β-peptide 1-42 / antioxidants / nuclei / conformational change / トリフルオロエタノール / グリコサミノグリカン / ドデシル硫酸ナトリウム / リゾフォスファチジン酸 / 陰性荷電 / アミロイド線維形成反応 / 界面活性剤 / Amyloid fibril / Dialysis-related amyloidosis / Beta2-microglobulin / Trifluoroethanol / Glycosamonoglycans / Sodium dodecyl sulfate / Lysophospholipids / Transgenic mouse / プロテオーム解析 / 免疫染色 / プロテオグリカン … More
Except Principal Investigator
アミロイドーシス / アルツハイマー病 / アミロイド線維 / 蛋白質 / アミロイド / 透析アミロイドーシス / apoA-II / β2-ミクログロブリン / 変性とフォールディング / シャペロン / マウス / 伝播 / PET / 病理学 / アミロイドβ蛋白 / 脳アミロイドアンギオパチー / 透析アミロイド症 / 生物物理 / 蛍光顕微鏡 / 脳神経疾患 / NMR / 細胞毒性 / 血液透析 / β2ミクログロブリン / 蛋白質品質管理 / β2-microglobulin / amyloid fibril / Amyloid fibril / Dialysis-related amyloidosis / Breast cancer / EMT / ecto-5'-nucleotidase / vimentin / 蛋白構造伝播 / pro-apoA-II / 核形成 / 線維伸長 / アデノウイルスベクター / 分子シャペロン / 蛋白構造 / プリオン / 線維形成 / 構造変換 / 人口血液透析 / 脂質 / 人工血液透析 / タンパク質 / オージェ電子 / 放射線治療 / 分子イメージング / apoA-II,ノックアウトマウス / 熱ショック蛋白質 / リポ蛋白質 / 疾患モデル / HDL / apoA-I / モデル動物 / ノックアウトマウス / SAA / 脳内出血 / MRI / 実験モデル / 天然フェノール化合物 / 脳画像 / 診断マーカー / 試験管内モデル / 動物モデル / 蛋白質の凝集 / 超音波 / アミロイド蛋白質 / 糖尿病 / β2‐ミクログロブリン / タウ蛋白 / タウオリゴマー / 神経細胞死 / ピオグリタゾン / オリゴマー / GSK3β / 透析アミロイド / B_2ミクログロブリン / 一次反応速度論 / AGEs(advanced glycation end products) / fAB_2-m / β_2ミクログロブリン / チオフラビンT / fAβ2-m線維伸長反応 / 一次反応速度論モデル / dialysis amyloidosis / β2-microgulobulin / first-order kinetics / advanced glycation end products / fAβィイD22ィエD2-m / ミスフォールディング / 線維構造 / 環境要因 / アミロイド-シス / in situ hybridization / amyloidosis / mouse / transmission / misfolding / fibril formation / environment / genetics / 蛋白質のフォールディング / 蛋白質の構造安定性 / 水素 / 重水素交換 / アミロイドβペプチド / アミロイド病 / フォールディング / 一分子観察 / Protein folding / Stability of proteins / Fluorescence microscopy / H / D exchange / Amyloid β-peptide / アミロイドβ蛋白(Aβ) / 脳血管障害 / 老化 / 遺伝子多型 / 疫学 / Aβ繊維分解薬 / Aβ線維分解薬 / 高齢者 / 危険因子 / アミロイドβタンパク(Aβ) / cerebral amyloid angiopathy (CAA) / amyloid β protein (Aβ) / Alzheimer's disease / cerebrovascular disorders / aging / geneticpolymorphism / epidemiology / anti-amyloidogenicagents / ナノマテリアル / 合成ペプチド / 蛋白質立体構造変化 / ナノテクノロジー / βアミロイド / 自己組織化 / ドデシル硫酸ナトリウム / βアミロイド線維 / 線維形成制御 / 分子間相互作用 / トリフルオロエタノール / グリコサミノグリカン / beta2-mocroglobulin / nano-material / synthetic peptide / conformational change / nanotechnology / beta amyloid / self-assembly / sinal transduction / 乳癌 / 組織アレイ / ecto 5'-nucleotidase / 免疫染色 / マイクロアレイ / GPI蛋白 / 細胞運動 / integrin β1 / signal transduction / がん / 細胞・組織 / 低酸素 / 酢酸 / 癌 / 腫瘍 / cancer / cell / tissue / hypoxia / acetate / 生体分子 / Biophysics / Biological molecules / Alzheimaer's disease / 滑膜細胞 / エンドサイトーシス / リソソーム / 滑膜線維芽細胞 / 細胞傷害 / 実験病理学 / IgM / 形質細胞 / 尿細管間質性腎炎 / 原発性胆汁性胆管炎 / 尿細管性アシドーシス / ファンコニー症候群 Less
  • Research Projects

    (47 results)
  • Research Products

    (227 results)
  • Co-Researchers

    (69 People)
  •  アミロイド線維形成を修飾する生体分子群の探索―試験管実験とプロテオーム解析の融合Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      University of Fukui
  •  Establishment of disease concept of new systemic disease "IgM-positive plasma cell related disease"

    • Principal Investigator
      高橋 直生
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      University of Fukui
  •  生理濃度のnMレベルでのβアミロイド線維形成の検出と分子間相互作用の解析

    • Principal Investigator
      長谷川 一浩
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      University of Fukui
  •  β2-ミクログロブリンアミロイド線維による細胞傷害機構、及び細胞刺激作用の解析

    • Principal Investigator
      大越 忠和
    • Project Period (FY)
      2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Fukui
  •  Molecular pathogenesis of amyloidosis: Integration of protein chemistry, mouse models and clinical pathologyPrincipal Investigator

    • Principal Investigator
      Naiki Hironobu
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Fukui
  •  Development of in vitro amyloid fibril formation systems that mimic the physiological fibrillogenesis conditions in vivo and their application to the analysis of fibril formation mechanism

    • Principal Investigator
      Hasegawa Kazuhiro
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      University of Fukui
  •  The mechanism of extracellular protein quality control by extracellular chaperone

    • Principal Investigator
      Ozawa Daisaku
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      University of Fukui
  •  analysis of the mechanism of bone and joint destruction by beta2-microglobulin amyloid deposion

    • Principal Investigator
      Okoshi Tadakazu
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      University of Fukui
  •  Molecular pathological environments promoting/inhibiting the development of amyloidosis: the synergistic interaction of protein science and animal modelsPrincipal Investigator

    • Principal Investigator
      Naiki Hironobu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Fukui
  •  Molecular mechanisms of Alzheimer's disease induced by oligomeric tau protein.

    • Principal Investigator
      HAMANO TADANORI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      University of Fukui
  •  Development of in vitro amyloid fibril formation systems that mimic the physiological fibrillogenesis conditions in vivo

    • Principal Investigator
      HASEGAWA Kazuhiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      University of Fukui
  •  The inhibition mechanism of protein aggregation by extracellular chaperone

    • Principal Investigator
      OZAWA Daisaku
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      University of Fukui
  •  analysis of the mechanism of bone and articular destruction in dialysis related amyloidosis

    • Principal Investigator
      OOKOSHI Tadakazu
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      University of Fukui
  •  アミロイド線維形成を制御する生体分子環境及び線維沈着による細胞傷害機構の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Fukui
  •  Clarification of the molecular pathogenesis of human amyloidosis by in vitro amyloid fibril formation systems and transgenic mouse modelPrincipal Investigator

    • Principal Investigator
      NAIKI Hironobu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Fukui
  •  Understanding the mechanism of amyloid fibrillation on the basis of single fibril and real-time observation

    • Principal Investigator
      GOTO Yuji)
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University
  •  アミロイド線維形成をもたらす生体分子環境および線維沈着による細胞傷害機構の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Fukui
  •  Systemic analysis of amyloidosis using animal models

    • Principal Investigator
      HIGUCHI Keiichi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Shinshu University
  •  Development of risk assessment and prevention of cerebral amyloid angiopathy-related cerebral hemorrhages

    • Principal Investigator
      YAMADA Masahito
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kanazawa University
  •  Studies on the molecular mechanism of amyloid fibril formation and on the role of extracellular quality control mechanism in the fibril formation.

    • Principal Investigator
      HESEGAWA Kazuhiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      University of Fukui
  •  オージェ電子放出ハロゲンを利用したアルツハイマー病の新しい治療法の開発

    • Principal Investigator
      清野 泰
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      University of Fukui
  •  アミロイド線維形成を引き起こす生体内分子環境の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      University of Fukui
  •  Molecular pathogenesis of dialysis-related amyloidosis-A fusion of the in vitro model and the animal model-Principal Investigator

    • Principal Investigator
      NAIKI Hironobu
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Fukui
  •  リゾリン脂質によるβ2-ミクログロブリンアミロイド線維の伸長促進効果

    • Principal Investigator
      大越 忠和
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Fukui
  •  Kinetic and thermodynamic analysis of the molecular interaction on amyloid fibril formation

    • Principal Investigator
      HASEGAWA Kazuhiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      University of Fukui
  •  β2-ミクログロブリンアミロイド線維形成・沈着の分子機構解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Fukui
  •  Basic Studies on Biochemical and Molecular Biological Diagnosis of Tumor Hypoxia by PET

    • Principal Investigator
      FURUKAWA Takako
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences
      University of Fukui
  •  アルツハイマー病βアミロイド線維の試験管内形成及び分解機構の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Fukui
  •  アミロイド線維形成を引き起こす生体内分子環境の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      University of Fukui
  •  Association between Ecto-5'-nucleotidase and Vimentin in Aggressive Breast Cancer Cells

    • Principal Investigator
      INAI Kunihiro
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Fukui
  •  アルツハイマー病βアミロイド線維の試験管内形成及び分解機構の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  Elucidation of the molecular pathogenesis of dialysis-related amyloidosis.Principal Investigator

    • Principal Investigator
      NAIKI Hironobu
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Fukui
      福井医科大学
  •  Elucidation and control of the molecular mechanism of amyloid fibril formation Applications for nano materials

    • Principal Investigator
      HASEGAWA Kazuhiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      ポストゲノムのナノサイエンス
    • Research Institution
      University of Fukui
      福井医科大学
  •  アルツハイマー病βアミロイド線維の試験管内形成及び分解機構の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  アミロイド線維形成の分子機構Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  Study on molecular pathogenesis and therapies for cerebral amyloid angiopathy

    • Principal Investigator
      YAMADA Masahito
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kanazawa University
  •  アルツハイマー病βアミロイド線維の試験管内形成及び分解機構の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  Understanding the amyloid fibril formation of β2-microglobulin on the basis of protein conformation

    • Principal Investigator
      GOTO Yuji
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      Osaka University
  •  アルツハイマー病βアミロイド線維の試験管内形成及び分解機構の解明Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      福井医科大学
  •  Analysis of the mechanism of misfolding to amyloid protein using mouse amyloidosis

    • Principal Investigator
      HIGUCHI Keiichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Experimental pathology
    • Research Institution
      Shinshu University
  •  アミロイド蛋白(apoA-II)の線維構造への変換を制御する分子シャペロン

    • Principal Investigator
      樋口 京一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Shinshu University
  •  Studies on the inhibitory mechanism of biological molecules and antioxidants for Alzheimer's β-amyloid fibril formation.Principal Investigator

    • Principal Investigator
      NAIKI Hironobu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      FUKUI MEDICAL UNIVERSITY
  •  Studies on dialysis-related amyloid fibril formation by a in vitro kinetic model

    • Principal Investigator
      GEJYO Fumitake
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Niigata University
      福井医科大学
  •  マウスアミロイド蛋白(apoA-II)の構造交換と分子シャペロン

    • Principal Investigator
      HIGUCH Keiichi
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Inhibitory effects of apolipoprotein E on Alzheimer's beta-amyloid fibril formation in vitro.Principal Investigator

    • Principal Investigator
      NAIKI Hironobu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Fukui Medical University
  •  アルツハイマー病βアミロイド線維重合の反応速度論的解析Principal Investigator

    • Principal Investigator
      内木 宏延
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      福井医科大学
  •  Effect of Pathogen Status on the Manifestation of Accelerated Senescence and Murine Senile Amyloidosis in Senescence Accelerated Mouse (SAM)Principal Investigator

    • Principal Investigator
      NAIKI Hironobu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      老化(加齢)
    • Research Institution
      Fukui Medical School

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

  • [Book] 多発性骨髄腫Updating 第6巻:ALアミロイドーシス、多発性骨髄腫の類縁疾患2014

    • Author(s)
      清水 一之, 安倍 正博, 島崎 千尋, 鈴木 憲史, 張 高明, 加藤 修明, 関島 良樹, 内木 宏延 他
    • Total Pages
      296
    • Publisher
      株式会社 医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Book] 変革する透析医学(透析アミロイドーシスの病態)2012

    • Author(s)
      小澤大作,風間順一郎,内木宏延
    • Total Pages
      5
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24770150
  • [Book] タンパク質の事典2008

    • Author(s)
      内木宏延
    • Total Pages
      863
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Book] タンパク質の事典(編 : 猪飼篤, 伏見譲, 卜部格, 上野川修一, 中村春木, 浜窪隆雄),"アミロイドタンパク質"2008

    • Author(s)
      内木宏延(分担執筆)
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Book] ルービン病理学-臨床医学への基盤2007

    • Author(s)
      内木 宏延, 他
    • Publisher
      西村書店
    • Data Source
      KAKENHI-PROJECT-18659249
  • [Journal Article] Autopsy case with concurrent transthyretin and immunoglobulin amyloidosis.2022

    • Author(s)
      Shintani‐Domoto Yukako、Ishino Kousuke、Naiki Hironobu、Sakatani Takashi、Ohashi Ryuji
    • Journal Title

      Pathol Int

      Volume: 72 Pages: 65-71

    • DOI

      10.1111/pin.13179

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07389, KAKENHI-PROJECT-21K06967
  • [Journal Article] 心アミロイドーシス2022

    • Author(s)
      池田 善彦, 内木 宏延
    • Journal Title

      病理と臨床

      Volume: 39(10) Pages: 988-992

    • Data Source
      KAKENHI-PROJECT-21K06967
  • [Journal Article] Development of Myeloperoxidase Anti-neutrophil Cytoplasmic Antibody-positive Necrotizing Crescentic Glomerulonephritis in an Elderly Patient with Immunological Kidney Disease2021

    • Author(s)
      Haruyoshi Yoshida, Naoki Takahashi, Takayasu Horiguchi, Hiroki Yasuhara, Tokuharu Tanaka, Yuhao Chen, Toshikazu Takasaki, Hitokazu Tsukao, Michiko Yoshida, Satoshi Kawakami, Makoto Ohta, Hironobu Naiki, Satoshi Konishi, Isao Ito, Masayuki Iwano
    • Journal Title

      Internal Medicine

      Volume: 60 Issue: 24 Pages: 3927-3935

    • DOI

      10.2169/internalmedicine.7252-21

    • NAID

      130008129501

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08630, KAKENHI-PROJECT-21K06967
  • [Journal Article] 蓄積病・アミロイドーシス2021

    • Author(s)
      内木 宏延
    • Journal Title

      病理と臨床

      Volume: 39(臨増) Pages: 266-269

    • Data Source
      KAKENHI-PROJECT-21K06967
  • [Journal Article] Case With Transthyretin Amyloid Cardiomyopathy Complicated With Rapidly Progressive Aortic Stenosis Possibly Caused by Amyloid Deposition in the Aortic Valve.2021

    • Author(s)
      Fujimoto T, Yamano T, Miyagawa-Hayashino A, Naiki H, Ueda M, Tasaki M, Yamano M, Zen K, Numata S, Matoba S.
    • Journal Title

      Circ Cardiovasc Imaging

      Volume: 14

    • DOI

      10.1161/circimaging.121.013357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07411, KAKENHI-PROJECT-21K06967
  • [Journal Article] Pathological review of cardiac amyloidosis using autopsy cases in a single Japanese institution2021

    • Author(s)
      Tateishi Y, Yamada Y, Katsuki M, Nagata T, Yamamoto H, Kohashi K, Koga Y, Hashisako M, Kiyozawa D, Mori T, Kuboyama Y, Kakinokizono A, Miyazaki Y, Yamaguchi A, Tsutsui H, Ninomiya T, Naiki H, Oda Y.
    • Journal Title

      Pathol Res Pract.

      Volume: 227 Pages: 153635-153635

    • DOI

      10.1016/j.prp.2021.153635

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06967, KAKENHI-PROJECT-19K16559
  • [Journal Article] Gastrointestinal AA amyloidosis secondary to chronic pyelonephritis presenting with refractory diarrhea and severe hypoalbuminemia.2021

    • Author(s)
      Tanaka Tomoko、Naito Tatsushi、Midori Yohei、Nosaka Takuto、Takahashi Kazuto、Ofuji Kazuya、Matsuda Hidetaka、Ohtani Masahiro、Hiramatsu Katsushi、Imamura Yoshiaki、Yokoyama Osamu、Naiki Hironobu、Nakamoto Yasunari
    • Journal Title

      Clin J Gastroenterol

      Volume: 14 Pages: 1642-1648

    • DOI

      10.1007/s12328-021-01508-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17456, KAKENHI-PROJECT-21K06967
  • [Journal Article] Human amyloidosis, still intractable but becoming curable: The essential role of pathological diagnosis in the selection of type‐specific therapeutics2020

    • Author(s)
      Naiki H, Sekijima Y, Ueda M, Ohashi K, Hoshii Y, Shimoda M, Ando Y.
    • Journal Title

      Pathology International

      Volume: 70 Pages: 191-198

    • DOI

      10.1111/pin.12902

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-19K07959, KAKENHI-PROJECT-18K07502, KAKENHI-PROJECT-19H03565
  • [Journal Article] Chronic hypoxia exacerbates diabetic glomerulosclerosis through mesangiolysis and podocyte injury in db/db mice2020

    • Author(s)
      Naoki Takahashi, Haruyoshi Yoshida, Hideki Kimura, Kazuko Kamiyama, Tomomi Kurose, Hidehiro Sugimoto, Toshio Imura, Seiji Yokoi, Daisuke Mikami, Kenji Kasuno, Hiroyuki Kurosawa, Yoshiaki Hirayama, Hironobu Naiki, Masanori Hara, Masayuki Iwano.
    • Journal Title

      Nephrology Dialysis Transplantation

      Volume: - Pages: 1678-1688

    • DOI

      10.1093/ndt/gfaa074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09692, KAKENHI-PROJECT-20K07844, KAKENHI-PROJECT-20K08630, KAKENHI-PROJECT-20H03696
  • [Journal Article] Apolipoprotein E and clusterin inhibit the early phase of amyloid-β aggregation in an in vitro model of cerebral amyloid angiopathy.2019

    • Author(s)
      Endo Y, Hasegawa K, Nomura R, Arishima H, Kikuta K, Yamashita T, Inoue Y, Ueda M, Ando Y, Wilson MR, Hamano T, Nakamoto Y, Naiki H.
    • Journal Title

      Acta Neuropathol Commun.

      Volume: 7 Pages: 12-12

    • DOI

      10.1186/s40478-019-0662-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-17H06972, KAKENHI-PROJECT-16K09235, KAKENHI-PROJECT-18K07502, KAKENHI-PROJECT-19K07909, KAKENHI-PROJECT-15K06965
  • [Journal Article] Amyloid formation under complicated conditions in which β2-microglobulin coexists with its proteolytic fragments.2019

    • Author(s)
      Muta Hiroya、So Masatomo、Sakurai Kazumasa、Kardos Jozsef、Naiki Hironobu、Goto Yuji
    • Journal Title

      Biochemistry

      Volume: 58 Pages: 4925-4934

    • DOI

      10.1021/acs.biochem.9b00917

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06352, KAKENHI-PROJECT-16H05170
  • [Journal Article] Possible mechanisms of polyphosphate-induced amyloid fibril formation of β2-microglobulin.2019

    • Author(s)
      Zhang Chun-ming、Yamaguchi Keiichi、So Masatomo、Sasahara Kenji、Ito Toru、Yamamoto Suguru、Narita Ichiei、Kardos Jozsef、Naiki Hironobu、Goto Yuji
    • Journal Title

      Proc. Natl. Acad. Sci. USA.

      Volume: 116 Pages: 12833-12838

    • DOI

      10.1073/pnas.1819813116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06352, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-17K07363
  • [Journal Article] Heating during agitation of β2-microglobulin reveals that supersaturation breakdown is required for amyloid fibril formation at neutral pH.2019

    • Author(s)
      Noji Masahiro、Sasahara Kenji、Yamaguchi Keiichi、So Masatomo、Sakurai Kazumasa、Kardos Jazsef、Naiki Hironobu、Goto Yuji
    • Journal Title

      J. Biol. Chem.

      Volume: 294 Pages: 15826-15835

    • DOI

      10.1074/jbc.ra119.009971

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06352, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-17K07363
  • [Journal Article] 老化とアミロイドーシス2018

    • Author(s)
      内木 宏延, 長谷川 一浩, 山口 格, 大越 忠和, 遠藤 芳徳
    • Journal Title

      病理と臨床

      Volume: 36 Pages: 110-115

    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Journal Article] Skin inflammation exacerbates food allergy symptoms in epicutaneously2018

    • Author(s)
      Kawasaki A, Ito N, Murai H, Yasutomi M, Naiki H, Ohshima Y
    • Journal Title

      Allergy

      Volume: 印刷中 Pages: 1313-1321

    • DOI

      10.1111/all.13404

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-16K19633, KAKENHI-PROJECT-16K10018
  • [Journal Article] Pathological examination of cerebral amyloid angiopathy in patients who underwent removal of lobar hemorrhages.2018

    • Author(s)
      Lin CM, Arishima H, Kikuta KI, Naiki H, Kitai R, Kodera T, Matsuda K, Hashimoto N, Isozaki M, Tsunetoshi K, Neishi H, Higashino Y, Akazawa A, Arai H, Yamada S
    • Journal Title

      J Neurol

      Volume: 265 Pages: 567-577

    • DOI

      10.1007/s00415-018-8740-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10713, KAKENHI-PROJECT-16H05170
  • [Journal Article] Aggregation-phase diagrams of β2-microglobulin reveal temperature and salt effects on competitive formation of amyloids versus amorphous aggregates.2018

    • Author(s)
      Masayuki Adachi, Masahiro Noji, Masatomo So, Kenji Sasahara, Jozsef Kardos, Hironobu Naiki, Yuji Goto
    • Journal Title

      J Biol Chem

      Volume: 293 Pages: 14775-14785

    • DOI

      10.1074/jbc.ra118.004683

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07363, KAKENHI-PLANNED-17H06352, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-17K15074
  • [Journal Article] Tubulointerstitial Nephritis with IgM-Positive Plasma Cells2017

    • Author(s)
      Takahashi N, Kimura H et al
    • Journal Title

      J Am Soc Nephrol.

      Volume: 28 Pages: 3688-3698

    • DOI

      10.1681/asn.2016101074

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08931, KAKENHI-PROJECT-17K08656, KAKENHI-PROJECT-17K09692, KAKENHI-PROJECT-16K15232, KAKENHI-PROJECT-26293201, KAKENHI-PROJECT-15H04836, KAKENHI-PROJECT-16H05138, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-15K09252
  • [Journal Article] Treatment with geranylgeranylacetone induces heat shock protein 70 and attenuates neonatal hyperoxic lung injury in a model of bronchopulmonary dysplasia.2017

    • Author(s)
      Shuko Tokuriki, Aiko Igarashi, Takashi Okuno, Genrei Ohta, Hironobu Naiki, Yusei Ohshima
    • Journal Title

      Lung

      Volume: - Pages: 28447205-28447205

    • DOI

      10.1007/s00408-017-0007-4

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26870229, KAKENHI-PROJECT-16H05170
  • [Journal Article] Heparin-induced amyloid fibrillation of beta2-microglobulin explained by solubility and a supersaturation-dependent conformational pahse diagram.2017

    • Author(s)
      So, M., Hata, Y., Naiki, H. and Goto, Y.
    • Journal Title

      Protein Sci

      Volume: 26 Pages: 1024-1036

    • DOI

      10.1002/pro.3149

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H00836, KAKENHI-PROJECT-15H04362, KAKENHI-PROJECT-15K14458, KAKENHI-PROJECT-16H05170
  • [Journal Article] Antiamyloidogenic and proamyloidogenic chaperone effects of C-reactive protein and serum amyloid P component.2017

    • Author(s)
      Ozawa D, Nomura R, Mangione PP, Hasegawa K, Okoshi T, Porcari R, Bellotti V, Naiki H.
    • Journal Title

      Amyloid

      Volume: 24(sup1) Pages: 28-29

    • DOI

      10.1080/13506129.2017.1295943

    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06965
  • [Journal Article] Significant association of cadaveric dura mater grafting with subpial Abeta deposition and meningeal amyloid angiopathy.2016

    • Author(s)
      Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H, Yamada M
    • Journal Title

      Acta Neuropathol

      Volume: 132(2) Pages: 313-315

    • DOI

      10.1007/s00401-016-1588-3

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25257506, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-26430060, KAKENHI-PROJECT-26860234, KAKENHI-PROJECT-15K08369, KAKENHI-PROJECT-16H06277
  • [Journal Article] アミロイドーシスの発症メカニズムについて2016

    • Author(s)
      大越忠和,小澤大作,山口格,長谷川一浩,内木宏延
    • Journal Title

      病理と臨床

      Volume: 34 Pages: 454-459

    • Data Source
      KAKENHI-PROJECT-26840047
  • [Journal Article] アミロイド線維の形成、沈着と臓器障害の分子機構2016

    • Author(s)
      大越忠和、内木宏延
    • Journal Title

      医学のあゆみ

      Volume: 258

    • Data Source
      KAKENHI-PROJECT-26860236
  • [Journal Article] アミロイド線維の形成・沈着と臓器障害の分子機構2016

    • Author(s)
      大越 忠和, 内木 宏延
    • Journal Title

      医学のあゆみ

      Volume: 258 Pages: 615-620

    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Journal Article] Molecular pathogenesis of human amyloidosis: Lessons from β2-microglobulin-related amyloidosis2016

    • Author(s)
      Naiki H, Okoshi T, Ozawa D, Yamaguchi I, Hasegawa K.
    • Journal Title

      Pathology International

      Volume: ;66(4) Pages: 193-201

    • DOI

      10.1111/pin.12394

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460893, KAKENHI-PROJECT-26840047, KAKENHI-PROJECT-26860236, KAKENHI-PROJECT-25293094, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-15K06965
  • [Journal Article] アミロイドーシスの発症メカニズムについて2016

    • Author(s)
      大越忠和、小澤大作、山口格、長谷川一浩、内木宏延
    • Journal Title

      病理と臨床

      Volume: 34 Pages: 454-459

    • Data Source
      KAKENHI-PROJECT-26860236
  • [Journal Article] Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro.2016

    • Author(s)
      Ozawa D, Nomura R, Mangione PP, Hasegawa K, Okoshi T, Porcari R, Bellotti V, Naiki H
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 29077-29077

    • DOI

      10.1038/srep29077

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-15K06965
  • [Journal Article] β2-ミクログロブリンアミロイド線維の形成機序2016

    • Author(s)
      小澤大作,大越忠和,長谷川一浩,内木宏延
    • Journal Title

      腎と骨代謝

      Volume: 印刷中

    • Data Source
      KAKENHI-PROJECT-26840047
  • [Journal Article] β2-ミクログロブリンアミロイド線維の形成機序2016

    • Author(s)
      小澤 大作, 大越 忠和, 長谷川 一浩, 内木 宏延
    • Journal Title

      腎と骨代謝

      Volume: 29 Pages: 199-206

    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Journal Article] アミロイドーシスの発症メカニズムについて2016

    • Author(s)
      大越 忠和, 小澤 大作, 山口 格, 長谷川 一浩, 内木 宏延
    • Journal Title

      病理と臨床

      Volume: 34 Pages: 454-459

    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Journal Article] A heterozygous female with Fabry disease due to a novel alpha-galactosidase A mutation exhibits a unique synaptopodin distribution in vacuolated podocytes2015

    • Author(s)
      Takahashi N, Yokoi S, Kasuno K, Kogami A, Tsukimura T, Togawa T, Saito S, Ohno K, Hara M, Kurosawa H, Hirayama Y, Kurose T, Yokoyama Y, Mikami D, Kimura H, Naiki H, Sakuraba H, Iwano M.
    • Journal Title

      Clin. Nephrol.

      Volume: 83 Pages: 301-308

    • DOI

      10.5414/cn108317

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590686, KAKENHI-PROJECT-25860399, KAKENHI-PROJECT-25293094
  • [Journal Article] Endocytosed β2-microglobulin amyloid fibrils induce necrosis and apoptosis of rabbit synovial fibroblasts by disrupting endosomal/lysosomal membranes: A novel mechanism on the cytotoxicity of amyloid fibrils.2015

    • Author(s)
      Okoshi, T., Yamaguchi, I., Ozawa, D., Hasegawa, H., Naiki, H.
    • Journal Title

      PLoS One

      Volume: 10

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Journal Article] 2-Microglobulin Amyloid Fibrils Induce Necrosis and Apoptosis of Rabbit SynovialFibroblasts by Disrupting Endosomal/Lysosomal Membranes: A Novel Mechanism on the Cytotoxicity of Amyloid Fibrils.2015

    • Author(s)
      Okoshi T, Yamaguchi I, Ozawa D, Hasegawa K, Naiki H
    • Journal Title

      PLoS One.

      Volume: 10

    • DOI

      10.1371/journal.pone.0139330

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06965, KAKENHI-PROJECT-25460893, KAKENHI-PROJECT-26840047, KAKENHI-PROJECT-26860236
  • [Journal Article] C-terminal sequence of amyloid-resistant type F apolipoprotein A-II inhibits amyloid fibril formation of apolipoprotein A-II in mice2015

    • Author(s)
      J.Sawashita, B.Zhang, K.Hasegawa, M.Mori, H.Naiki, F.Kametani, K.Higuchi.
    • Journal Title

      Proc Natl Acad Sci U SA.

      Volume: 112

    • DOI

      10.1073/pnas.1416363112

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24570129, KAKENHI-PROJECT-25293094, KAKENHI-PROJECT-26293084, KAKENHI-PROJECT-26670152, KAKENHI-PROJECT-25460893
  • [Journal Article] Utility of postmortem imaging system for anatomical education in skull base surgery2015

    • Author(s)
      Kodera T, Arishima H, Kitai R, Kikuta K, Iino S, Noriki S, Naiki H.
    • Journal Title

      Neurosurg. Rev.

      Volume: 38 Pages: 165-170

    • DOI

      10.1007/s10143-014-0574-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590250, KAKENHI-PLANNED-26108009, KAKENHI-PROJECT-15K08150, KAKENHI-PROJECT-25221205, KAKENHI-PROJECT-26670348, KAKENHI-PROJECT-25293094
  • [Journal Article] HBME-1 and CD15 immunocytochemistry in the follicular variant of thyroid papillary carcinoma.2015

    • Author(s)
      Ohta, M., Ookoshi, T., Naiki, H., Imamura, Y.
    • Journal Title

      Pathol Int.

      Volume: 65 Pages: 119-125

    • DOI

      10.1111/pin.12252

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Journal Article] Supersaturation-limited and unlimited phase spaces compete to produce maximal amyloid fibrillation near the critical micelle concentration of sodium dodecyl sulfate.2015

    • Author(s)
      So, M., Ishii, A., Hata, Y., Yagi, H., Naiki, H. and Goto, Y.
    • Journal Title

      Langmuir

      Volume: 31(36) Pages: 9973-9982

    • DOI

      10.1021/acs.langmuir.5b02186

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04362, KAKENHI-PROJECT-25293094
  • [Journal Article] ヒトアミロイド線維形成・沈着の分子機構2014

    • Author(s)
      内木宏延,長谷川一浩,小澤大作,大越忠和
    • Journal Title

      Dementia Japan

      Volume: 28 Pages: 275-282

    • Data Source
      KAKENHI-PROJECT-26840047
  • [Journal Article] Heat of supersaturation-limited amyloid burst directly monitored by isothermal titration calorimetry.2014

    • Author(s)
      Ikenoue T, Lee YH, Kardos J, Yagi H, Ikegami T, Naiki H, Goto Y.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Journal Article] Heat of supersaturation-limited amyloid burst directly monitored by isothermal titration calorimetry2014

    • Author(s)
      Ikenoue, T., Lee, Y.-H., Kardos, J., Yagi, H., Ikegami, T., Naiki, H. and Goto, Y.
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 111 Pages: 6654-6659

    • DOI

      10.1073/pnas.1322602111

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24370067, KAKENHI-PROJECT-25293094, KAKENHI-PROJECT-25870407
  • [Journal Article] ヒトアミロイド線維形成・沈着の分子機構2014

    • Author(s)
      内木 宏延, 長谷川 一浩, 小澤 大作, 大越 忠和
    • Journal Title

      Dementia Japan

      Volume: 28 Pages: 275-282

    • Data Source
      KAKENHI-PROJECT-25293094
  • [Journal Article] ヒトアミロイド線維形成・沈着の分子機構2014

    • Author(s)
      内木 宏延, 長谷川 一浩, 小澤 大作, 大越 忠和
    • Journal Title

      Dementia Japan

      Volume: 28 Pages: 275-282

    • Data Source
      KAKENHI-PROJECT-24570129
  • [Journal Article] 腎アミロイドーシスの診断と線維形成機序2013

    • Author(s)
      高橋 直生, 岩野 正之, 内木 宏延, 木村 秀樹
    • Journal Title

      Nephrolgy Frontier

      Volume: 12 (1)

    • Data Source
      KAKENHI-PROJECT-25293094
  • [Journal Article] Suface-bound basement membrane components accelerate amyloid- peptide nucleation in air-free wells: an in vitro model of cerebral amyloid angiopathy2013

    • Author(s)
      Hasegawa K, Ozawa D, Ookoshi T, Naiki H
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1834 Pages: 1624-1631

    • DOI

      10.1016/j.bbapap.2013.04.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24570129, KAKENHI-PROJECT-24770150, KAKENHI-PROJECT-25293094
  • [Journal Article] Surface-bound basement membrane components accelerate amyloid-β peptide nucleation in air-free wells: an in vitro model of cerebral amyloid angiopathy2013

    • Author(s)
      Hasegawa K., Ozawa D, Ookoshi T, Naiki H
    • Journal Title

      BiochimBiophys Acta

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Cerebral amyloid angiopathy2012

    • Author(s)
      Yamada M, Naiki H
    • Journal Title

      Prog Mol Biol Transl Sci

      Volume: 107 Pages: 41-78

    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Cerebral amyloid angiopathy2012

    • Author(s)
      Yamada M, Naiki H
    • Journal Title

      Prog Mol Biol Transl Sci

      Volume: 107 Pages: 41-78

    • DOI

      10.1016/b978-0-12-385883-2.00006-0

    • NAID

      40016785952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390242
  • [Journal Article] Polymorphism of β_2-microglobulin amyloidfibrils manifested by ultrasonication-enhanced fibril formation in trifluoroethanol.2012

    • Author(s)
      Chatani E, Yagi H, Naiki H, Goto Y
    • Journal Title

      J Biol Chem

      Volume: 287(27) Pages: 22827-22837

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Molecular mechanisms ofβ2-microglobulin amyloid fibril formation2012

    • Author(s)
      Ozawa D, Hasegawa K, Ookoshi T, Naiki H
    • Journal Title

      The Proceedings of the XIIIth International Symposium on Amyloidosis

      Pages: 45-47

    • Data Source
      KAKENHI-PROJECT-24770150
  • [Journal Article] Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation2012

    • Author(s)
      Yoshimura Y, Lin Y, Yagi H, Lee YH, Kitayama H, Sakurai K, So M, Ogi H, Naiki H, Goto Y
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 109(36) Pages: 14446-14451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] The monomer-seed interaction mechanism in the formation of the β2-microglobulin amyloid fibril clarified by solution NMR techniques2012

    • Author(s)
      Yanagi K, Sakurai K, Yoshimura Y, Konuma T, Lee YH, Sugase K, Ikegami T, Naiki H, Goto Y
    • Journal Title

      J Mol Biol

      Volume: 422(3) Pages: 390-402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Destruction of amyloid fibrils of keratoepithelin peptides by laser irradiation coupled with amyloid-specific thioflavin2011

    • Author(s)
      T. Ozawa, D., Kaji, Y., Yagi, H., Sakurai, K., Kawakami, T., Naiki, N. & Goto, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 286 Pages: 10856-10863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Inhibition of. 2-microglobulin amyloid fibril formation byα2-macroglobulin2011

    • Author(s)
      Ozawa, D., Hasegawa, K., Lee, Y. H., Sakurai, K., Yanagi, K., Ookoshi, T., Goto, Y., Naiki, H.
    • Journal Title

      J. Biol. Chem.

      Volume: 286 Pages: 9668-9676

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Reversible heat-induced dissociation ofβ2-microglobulin amyloid fibrils2011

    • Author(s)
      Kardos, J., Micsonai, A., Pa. l-Ga. bor, H., Petrik, E., Gra. f, L., Kova. cs, J., Lee, Y. H., Naiki, H. & Goto, Y.
    • Journal Title

      Biochemistry

      Volume: 50 Pages: 3211-3220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Inhibition of β2-microglobulin amyloid fibril formation by_a2-macroglobulin.2011

    • Author(s)
      Ozawa D, Hasegawa K, Lee YH, Sakurai K, Yanagi K, Ookoshi T, Goto Y, Naiki H.
    • Journal Title

      J Biol Chem. 286(11)

      Pages: 9668-9676

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Journal Article] Reversible heat-induced dissociation of β_2-microglobulin amyloid fibrils.2011

    • Author(s)
      Kardos J, Micsonai A, Pal-Gabor H, Petrik e, Graf L, Kovacs J, Lee YH, Naiki H, Goto Y
    • Journal Title

      Biochemistry

      Volume: 50(15) Pages: 3211-3220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Kinetic intermediates ofβ2-microglobulin fibril elongation probed by pulse-labeling H/ D exchange combined with NMR analysis2011

    • Author(s)
      Konuma, T., Chatani, E., Yagi, M., Sakurai, K., Ikegami, T., Naiki, H. & Goto, Y.
    • Journal Title

      J. Mol. Biol.

      Volume: 405 Pages: 851-862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Inhibition of β_2-microglobulin amyloid fibril formation by α_2-macroglobulin.2011

    • Author(s)
      Ozawa D, Hasegawa K, Lee YH, Sakurai K, Yanagi K, Ookoshi T, Goto Y, Naiki H
    • Journal Title

      J Biol Chem

      Volume: 286(11) Pages: 9668-9676

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Kinetic intermediates of β_2-microglobulin fibril elongation probed by pulse-labeling H/D exchange combined with NMR analysis2011

    • Author(s)
      Konuma T, Chatani E, Yagi M, Sakurai K, Ikegami T, Naiki H, Goto Y
    • Journal Title

      J Mol Biol

      Volume: 405(3) Pages: 851-862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] アミロイドーシス2011

    • Author(s)
      高橋直生, 木村秀樹, 吉田治義, 内木宏延
    • Journal Title

      日内会誌

      Volume: 100(5) Pages: 1282-1288

    • NAID

      10029097141

    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Ultrasonication-dependent acceleration of amyloid fibril formation2011

    • Author(s)
      So, M., Yagi, H., Sakurai, K., Ogi, H., Naiki, H. & Goto, Y.
    • Journal Title

      J. Mol. Biol.

      Volume: 412 Pages: 568-577

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Destruction of amyloid fibrils of keratoepithelin peptides by laser irradiation coupled with amyloid-specific thioflavin2011

    • Author(s)
      Ozawa D, Kaji Y, Yagi H, Sakurai K Kawakami T, Naiki H, Goto Y
    • Journal Title

      T. J Biol Chem

      Volume: 286(12) Pages: 10856-10863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Ultrasonication-dependent acceleration of amyloid fibril formation2011

    • Author(s)
      So M, Yagi H, Sakurai K, Ogi H, Naiki H, Goto Y .
    • Journal Title

      J Mol Biol

      Volume: 412(4) Pages: 568-577

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] アミロイド線維形成の重合核依存性重合モデルと線維形成阻害薬の探索2010

    • Author(s)
      内木宏延, 他
    • Journal Title

      薬学雑誌

      Volume: 130 Pages: 503-509

    • NAID

      130000259538

    • Data Source
      KAKENHI-PROJECT-20570105
  • [Journal Article] アミロイド線維形成の重合核依存性重合モデルと線維形成阻害薬の探索2010

    • Author(s)
      内木宏延, 長谷川一浩, 小野賢二郎, 山田正仁
    • Journal Title

      薬学雑誌

      Volume: 130(4) Pages: 503-509

    • NAID

      130000259538

    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Critical role of interfaces and agitation on the nucleation of Aβ amyloid fibrils at low concentrations of Aβ monomers.2010

    • Author(s)
      Morinaga A, Hasegawa K, Nomura R, Ookoshi T, Ozawa D, Goto Y, Yamada M, Naiki H.
    • Journal Title

      Biochem Biophys Acta - Proteins and Proteomics 1804

      Pages: 986-995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390242
  • [Journal Article] Direct observation of minimum-sized amyloid fibrils using solution NMR spectroscopy2010

    • Author(s)
      Yoshimura, Y., Sakurai, K., Lee, Y.-H., Ikegami, T., Chatani, E., Naiki, H. & Goto, Y.
    • Journal Title

      Protein Sci.

      Volume: 19 Pages: 2347-2355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Direct observation of minimum-sized amyloid fibrils using solution NMR spectroscopy2010

    • Author(s)
      Yoshimura Y, Sakurai K, Lee YH, Ikegami T, Chatani E, Naiki H, Goto Y
    • Journal Title

      Protein Sci

      Volume: 19(12) Pages: 2347-2355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] 透析アミロイドーシス発症の分子機構2010

    • Author(s)
      内木宏延
    • Journal Title

      医学のあゆみ

      Volume: 別册 Pages: 75-81

    • Data Source
      KAKENHI-PUBLICLY-22020014
  • [Journal Article] Critical role of interfaces and agitation on the nucleation of Aβ amyloid fibrils at low concentrations of Aβ monomers2010

    • Author(s)
      Morinaga A, Hasegawa K, Nomura R, Ookoshi T, Ozawa D, Goto Y, Yamada M, Naiki H
    • Journal Title

      Biochem Biophys Acta-Proteins and Proteomics 1804

      Pages: 986-995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390242
  • [Journal Article] Critical role of interfaces and agitation on the nucleation of Abeta amyloid fibrils at low concentrations of Abeta monomers.2010

    • Author(s)
      Morinaga A, Hasegawa K, Nomura R, Ookoshi T, Ozawa D, Goto Y, Yamada M, Naiki H.
    • Journal Title

      Biochim Biophys Acta. 1804(4)

      Pages: 986-995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Journal Article] アミロイド線維形成の重合核依存性重合モデルと線維形成阻害薬の探索2010

    • Author(s)
      内木宏延, 他
    • Journal Title

      薬学雑誌

      Volume: 130 Pages: 503-509

    • NAID

      130000259538

    • Data Source
      KAKENHI-PUBLICLY-22020014
  • [Journal Article] Mouse model to study human Aβ32M amyloidosis : Generation of a transgenic mouse with excessive expression of human β32-microglobulin.2010

    • Author(s)
      Zhang P, Fu X, Sawashita J, Yao J, Zhang B, Qian J, Tomozawa H, Mori M, Ando Y, Naiki H, Higuchi K
    • Journal Title

      Amyloid 17

      Pages: 50-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300144
  • [Journal Article] 透析アミロイドーシス発症の分子機構2010

    • Author(s)
      内木宏延
    • Journal Title

      医学のあゆみ

      Pages: 75-81

    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Laser-induced propagation and destruction of amyloidβfibrils2010

    • Author(s)
      Yagi, H., Ozawa, D., Sakurai, K., Kawakami, T., Kuyama, H., Nishimura, O., Shimanouchi, T., Kuboi, R., Naiki, H. & Goto, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 285 Pages: 19660-19667

    • NAID

      120006557646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Critical role of interfaces and agitation on the nucleation of Aβamyloid fibrils at low concentrations of Aβmonomers2010

    • Author(s)
      Morinaga A, Hasegawa K, Nomura R, Ookoshi T, Ozawa D, Goto Y, Yamada M, Naiki H
    • Journal Title

      Biochem Biophys Acta-Proteins and Proteomics

      Volume: 1804 Pages: 986-995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390242
  • [Journal Article] Amyloid fibrils of the constant domain of immunoglobulin light chain2010

    • Author(s)
      Yamamoto, K., Yagi, H., Lee, Y. H., Kardos, K., Hagihara, Y., Naiki, H. & Goto, Y.
    • Journal Title

      FEBS Lett.

      Volume: 584 Pages: 3348-3353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Pre-steady state kinetic analysis for the elongation of amyloid fibrils ofβ2-microglobulin with tryptophan mutagenesis2010

    • Author(s)
      Chatani, E., Ohnishi1, R., Konuma, T., Sakurai, K., Naiki, N. & Goto, Y.
    • Journal Title

      J. Mol. Biol.

      Volume: 400 Pages: 1057-1066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] アミロイド線維形成の重合核依存性重合モデルと線維形成阻害薬の探索2010

    • Author(s)
      内木宏延, 他
    • Journal Title

      薬学雑誌

      Volume: 130 Pages: 503-509

    • NAID

      130000259538

    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Mouse model to study human Aβ_2M amyloidosis: generation of a transgenic mouse with excessive expression of human β_2-microglobulin2010

    • Author(s)
      Zhang P, Fu X, Sawashita J, Yao J, Zhang B, Qian J, Tomozawa H, Mori M, Ando Y, Naiki H, Higuchi K
    • Journal Title

      Amyloid

      Volume: 17(2) Pages: 50-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Laser-induced propagation and destruction of amyloid β fibrils2010

    • Author(s)
      Yagi H, Ozawa D, Sakurai K, Kawakami T, Kuyama H, Nishimura O, Shimanouchi T, Kuboi R, Naiki H, Goto Y
    • Journal Title

      J Biol Chem

      Volume: 285(25) Pages: 19660-19667

    • NAID

      120006557646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] The amyloid fibrils of the constant domain of immunoglobulin light chain2010

    • Author(s)
      Yamamoto K, Yagi H, Lee YH, Kardos J, Hagihara Y, Naiki H, Goto Y
    • Journal Title

      FEBS Lett

      Volume: 584(15) Pages: 3348-3353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] Pre-steady-state kinetic analysis of the elongation of amyloid fibrils of β_2-microglobulin with tryptophan mutagenesis2010

    • Author(s)
      Chatani E, Ohnishi R, Konuma T, Sakurai K, Naiki H, Goto Y
    • Journal Title

      J Mol Biol

      Volume: 400(5) Pages: 1057-1066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Journal Article] A comprehensive model for packing and hydration for amyloid fibrils of. 2-microglobulin2009

    • Author(s)
      Lee, Y.-H., Chatani, E., Sasahara, K., Naiki, H. & Goto, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 284 Pages: 2169-2175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Amyloid fibrils formed by selective N-, C-terminal sequences of mouse apolipoprotein A-II.2009

    • Author(s)
      Sawashita J, Kametani F, Hasegawa K, Tsutsumi-Y S, Zhang B, Yan J, Mori M, Naiki H, Higuchi K
    • Journal Title

      Biochim Biophys Acta-Proteins & Proteomics 1794

      Pages: 1517-1529

    • NAID

      120007110403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300144
  • [Journal Article] アミロイドーシス2009

    • Author(s)
      内木宏延
    • Journal Title

      病理と臨床 27

      Pages: 273-279

    • NAID

      10029097141

    • Data Source
      KAKENHI-PROJECT-20059015
  • [Journal Article] Thermal response with exothermic effects of. 2-microglobulin amyloid fibrils and fibrillation2009

    • Author(s)
      Sasahara, K., Yagi, H., Naiki, H. & Goto, Y.
    • Journal Title

      J. Mol. Biol.

      Volume: 389 Pages: 584-594

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] アミロイド線維の形成・沈着機構-重合核依存性重合モデルを中心に-2009

    • Author(s)
      内木宏延, 他
    • Journal Title

      神経内科 70

      Pages: 129-135

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Ultrasonication establishes the equilibrium between production and breakdown leading to the minimum-sized amyloid fibrils2009

    • Author(s)
      Chatani, E., Lee, Y.-H., Yagi, H., Yoshimura, Y., Naiki, N. & Goto, Y.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 106 Pages: 11119-11124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] Molecular pathogenesis of protein misfolding diseases : pathological molecular environments versus quality control systems against misfolded proteins2009

    • Author(s)
      Naiki, H., et al.
    • Journal Title

      J.Biochem. 146

      Pages: 751-756

    • NAID

      10026304899

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20059015
  • [Journal Article] Destruction of amyloid fibrils of a β2-microgobulin fragment by laser beam irradiation2009

    • Author(s)
      Ozawa, D., Yagi, H., Ban, T.Kameda, A., Kawakami,T., Naiki, H., Goto, Y.
    • Journal Title

      J. Biol. Chem 284(2)

      Pages: 1009-1017

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] A comprehensive model for packing and hydration for amyloid fibrils of β2-microglobulin2009

    • Author(s)
      Lee, Y-H., Chatani, E., Sasahara, K., Naiki, H., Goto, Y.
    • Journal Title

      J. Biol. Chem 284(4)

      Pages: 2169-2175

    • NAID

      120006557647

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Amyloid fibrils formed by selective N-, C-terminal sequences of mouse apolipoprotein A-II.2009

    • Author(s)
      Sawashita J, Kametani F, Hasegawa K, Tsutsumi-Yasuhara S, Zhang B, Yan J, Mori, M, Naiki H, Higuchi K.
    • Journal Title

      Biochim Biophys Acta. 1794(10)

      Pages: 1517-1529

    • NAID

      120007110403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Journal Article] NMR-based characterization of a refolding intermediate ofβ2-microglobulin labeled amino acid selectively using a wheat germ cell-free system2009

    • Author(s)
      Kameda, A., Morita, E.-H., Sakurai, K., Naiki, N. & Goto, Y.
    • Journal Title

      Protein Sci.

      Volume: 18 Pages: 1592-1601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] アミロイド線維の形成・沈着機構-重合核依存性重合モデルを中心に-2009

    • Author(s)
      内木宏延, 他
    • Journal Title

      神経内科 70

      Pages: 129-135

    • Data Source
      KAKENHI-PROJECT-20059015
  • [Journal Article] Destruction of amyloid fibrils of aβ2-microglobulin fragment by laser beam irradiation2009

    • Author(s)
      Ozawa, D., Yagi, H., Ban, T., Kameda, A., Kawakami, T., Naiki, H., & Goto, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 284 Pages: 1009-1017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370044
  • [Journal Article] 透析アミロイドーシス発症の分子機構2009

    • Author(s)
      内木宏延
    • Journal Title

      医学のあゆみ 229

      Pages: 377-383

    • Data Source
      KAKENHI-PROJECT-20059015
  • [Journal Article] Procollagen C-proteinase enhancer-1(PCPE-1)interacts with β2-microglobulin(β2-m)and may help initiate β2-m amyloid fibril formation in connective tissues2008

    • Author(s)
      Morimoto, H., Wada, J., Font, B., Mott, J.D., Hulmes D.J., Ookoshi, T., Naiki, H., Yasuhara, A., Nakatsuka, A., Fukuoka, K., Takatori, Y., Ichikawa, H., Akagi, S., Nakao, K., Makino, H.
    • Journal Title

      Matrix Biol 27(3)

      Pages: 211-219

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] アミロイド2008

    • Author(s)
      内木宏延
    • Journal Title

      蛋白質核酸酵素 53

      Pages: 906-906

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] アルロイド2008

    • Author(s)
      内木宏延
    • Journal Title

      蛋白質核酸酵素 53

      Pages: 906-906

    • Data Source
      KAKENHI-PROJECT-20059015
  • [Journal Article] チオフラビンT2008

    • Author(s)
      内木宏延
    • Journal Title

      蛋白質核酸酵素 53

      Pages: 968-968

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Growth of β2-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH2008

    • Author(s)
      Hasegawa, K., Tsutsumi-Yasuhara, S., Ookoshi, T., Ohhashi,Y., Kimura, H., Takahashi, N., Yoshida, H., Miyazaki, R., Goto, Y., Naiki, H.
    • Journal Title

      Biochem.J 416(2)

      Pages: 307-315

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Growth of β2-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH.2008

    • Author(s)
      Hasegawa K, Tsutsumi-Yasuhara S, Ookoshi T, Ohhashi Y, Kimura H, Takahashi N, Yoshida H, Miyazaki R, Goto Y, Naiki H.
    • Journal Title

      Biochem J. 416(2)

      Pages: 307-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Journal Article] Lysophospholipids induce the nucleation and extension of β2-microglobulin-related amyloid fibrils at a neutral pH2008

    • Author(s)
      Ookoshi, T. Hasegawa, K., Ohhashi, Y., Kimura, H., Takahashi, N., Yoshida, H., Miyazaki, R., Goto, Y., Naiki, H.
    • Journal Title

      Nephrol. Dial. Transplant 23(10)

      Pages: 3247-3255

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Inhibitors of amyloid β-protein aggregation mediated by GM1-containing raft-like membranes2007

    • Author(s)
      Matsuzaki, K., Noguch, T., Wakabayashi, M., Ikeda, K., Okada, T., Ohashi, Y., Hoshino, M., Naiki, H.
    • Journal Title

      Biochim. Biophys. Acta-Biomembranes 1768(1)

      Pages: 122-130

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] The anti-amyloidogenic effect is exerted against Alzheimer's beta-amyloid fibrils in vitro by preferential and reversible binding of flavonoids to the amyloid fibril structure2007

    • Author(s)
      Hirohata, M., Hasegawa, K., Tsutsumi-Yasuhara, S., Ohhashi, Y., Ookoshi, T., Ono, K., Yamada, M., Naiki, H
    • Journal Title

      Biochemistry 46(7)

      Pages: 1888-1899

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570149
  • [Journal Article] A toxic monomeric conformer of the polyglutamine protein.2007

    • Author(s)
      Nagai, Y., Inui, T., Popiel, HA., Fujikake, N., Hasegawa, K., Urade, Y., Goto, Y., Naiki, H., Toda, T
    • Journal Title

      Nat. Struct. Mol. Biol 14(4)

      Pages: 332-340

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570149
  • [Journal Article] Visualization and classification of amyloid β supramolecular assemblies2007

    • Author(s)
      Yagi, H., Ban, T. Morigaki, K., Naiki, H., Goto, Y.
    • Journal Title

      Biochemistry 46(51)

      Pages: 15009-15017

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] The anti-amyloidogenic effect is exerted against Alzheimer's β-amyloid fibrils in vitro by preferential and reversible binding of flavonoids to the amyloid fibril structure2007

    • Author(s)
      Hirohata, M., Hasegawa, K., Tsutsumi-Yasuhara, S., Ohhashi, Y., Ookoshi, T., Ono, K., Yamada, M., Naiki, H.
    • Journal Title

      Biochemistry 46(7)

      Pages: 1888-1899

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] A toxic monomeric conformer of the polyglutamine protein.2007

    • Author(s)
      Nagai, Y., Inui, T., Popiel, H.A., Fujikake, N., Hasegawa, K., Urade, Y., Goto, Y., Naiki, H., Toda, T.
    • Journal Title

      Nat. Struct. Mol. Biol 14(4)

      Pages: 332-340

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Frequent Detection of Multi-drug Resistant Pneumonia-causing Bacteria in the Lung Tissues of Patients with Hematological Malignancies2007

    • Author(s)
      Inai K, Iwasaki H, Noriki S, Ikegaya S, Yamashita M, Imamura Y, Takimoto N, Kato H, Ueda T, Naiki H.
    • Journal Title

      Int. J. Hematol.

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590306
  • [Journal Article] 透析アミロイドーシス-基礎研究から治療戦略Update-2007

    • Author(s)
      内木 宏延, 他
    • Journal Title

      透析会誌 40

      Pages: 1025-1025

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Cross-seeding and cross-competition in mouse apolipoprotein A-II amyloid fibrils and protein A amyloid fibrils2007

    • Author(s)
      Yan, J., Fu, X., Ge, F., Zhang, B., Yao, J., Zhang, H., Qian, J., Tomozawa, H., Naiki, H., Sawashita, J., Mori, M., Higuchi, K.
    • Journal Title

      Am.J.Pathol 171(1)

      Pages: 172-180

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] 透析アミロイドーシス-基礎研究から治療戦略Update-2007

    • Author(s)
      内木 宏延, 他
    • Journal Title

      透析会誌 40

      Pages: 1025-1025

    • Data Source
      KAKENHI-PROJECT-18031014
  • [Journal Article] Conformation of amyloid fibrils of β2-microglobulin probed by tryptophan mutagenesis2006

    • Author(s)
      Kihara, M., Chatani, E., Iwata, K., Yamamoto, K., Matsuura, T., Nakagawa, A., Naiki, H., Goto, Y.
    • Journal Title

      J.Biol.Chem 281(41)

      Pages: 31061-31069

    • NAID

      120006557652

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] 3D structure of amyloid protofilaments of β2-microglobulin fragment probed by solid-state NMR2006

    • Author(s)
      Iwata, K., Fujiwara, T., Matsuki, Y., Akutsu, H., Takahashi, S., Naiki, H., Goto, Y.
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A. 103(48)

      Pages: 18119-18124

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Real-time and single fibril observation of the formation of amyloid β spherulitic structures2006

    • Author(s)
      Ban, T., Morigaki, K., Yagi, H., Kawasaki, T., Kobayashi, A., Yuba, S., Naiki, H., Goto, Y.
    • Journal Title

      J.Biol.Chem 281(44)

      Pages: 33677-33683

    • NAID

      120006557651

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Seeding-dependent propagation and maturation of β_2-microglobulin amyloid fibrils under high pressure2006

    • Author(s)
      Chatani, E., Naiki, H., Goto, Y.
    • Journal Title

      J. Mol. Biol 359(4)

      Pages: 1086-1096

    • Data Source
      KAKENHI-PROJECT-18390120
  • [Journal Article] Molecular interactions in the formation and deposition of β_2-microglobulin-related amyloid fibrils.2005

    • Author(s)
      Naiki, H. et al.
    • Journal Title

      Amyloid 12(1)

      Pages: 15-25

    • Data Source
      KAKENHI-PROJECT-16041217
  • [Journal Article] Molecular interactions in the formation and deposition of β_2-microglobulin-related amyloid fibrils.2005

    • Author(s)
      Naiki, H. et al.
    • Journal Title

      Amyloid 12(1)

      Pages: 15-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390123
  • [Journal Article] Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro.2004

    • Author(s)
      Ono K, Hasegawa K, Naiki H, Yamada M.
    • Journal Title

      Biochim Biophys Acta (Molecular Basis of Disease) 1690

      Pages: 193-202

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370203
  • [Journal Article] Vitamin A exhibits potent anti-amyloidogenic and fibril-destabilizing effects in vitro.2004

    • Author(s)
      Ono K, Yoshiike Y, Takashima A, Hasegawa K, Naiki H, Yamada M.
    • Journal Title

      Exp Neurol 189

      Pages: 380-392

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370203
  • [Journal Article] Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta amyloid fibrils in vitro.2004

    • Author(s)
      Ono K, Hasegawa K, Naiki H, Yamada M.
    • Journal Title

      J Neurosci Res 75

      Pages: 742-750

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370203
  • [Journal Article] Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro : Implications for the prevention and therapeutics of Alzheimer's disease.2003

    • Author(s)
      Ono K, Yoshiike Y, Takashima A, Hasegawa K, Naiki H, Yamada M.
    • Journal Title

      J Neurochem 87

      Pages: 172-181

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370203
  • [Journal Article] Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer's β-amyloid fibrils in vitro.2002

    • Author(s)
      Ono K, Hasegawa K, Yoshiike Y, Takashima A, Yamada M, Naiki H.
    • Journal Title

      J Neurochem 81

      Pages: 434-440

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370203
  • [Journal Article] Nicotine breaks down preformed Alzheimer's β-amyloid fibrils in vitro.2002

    • Author(s)
      Ono K, Hasegawa K, Yamada M, Naiki H.
    • Journal Title

      Biol Psychiatry 52

      Pages: 880-886

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370203
  • [Journal Article] Kinetic modeling and determination of reaction constants of Alzheimer's β-amyloid fibril extension and dissociation using surface plasm on resonance.2002

    • Author(s)
      Hasegawa K, Ono K, Yamada M, Naiki H.
    • Journal Title

      Biochemistry 41

      Pages: 13489-13498

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370203
  • [Journal Article] Cerebral amyloid anigopathy

    • Author(s)
      Yamada M, Naiki H
    • Journal Title

      Prog Mol Biol Transl Sci

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390242
  • [Journal Article] Lysophospholipids Induce the Nucleation and Extension of β2-Microglobulin-Related Amyloid Fibrils at a Neutral pH

    • Author(s)
      Ookoshi, T., Hasegawa, K., Ohhashi, Y., Kimura, H., Takahashi, N., Yoshida, H., Miyazaki, R., Goto, Y., Naiki, H
    • Journal Title

      Nephrol. Dial. Transplant (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570149
  • [Presentation] アミロイドーシス発症の分子機構2022

    • Author(s)
      内木 宏延
    • Organizer
      第41回日本画像医学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K06967
  • [Presentation] ヒト全身性アミロイドーシス:発症の分子機構と病理組織学的診断2021

    • Author(s)
      内木 宏延
    • Organizer
      第110回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06967
  • [Presentation] 大型放射光施設SPring-8のX線位差CTを用いた心・腎アミロイドーシス組織の構造解析とイメージング質量分析法を用いた組織プロテオーム解析の統合2021

    • Author(s)
      武笠 結天, 袴田 圭祐, 升本 英利, 新谷 祈, 外山 友美子, 辻 崇, 徳平 壮一郎, 星野 真人, 八木 直人, 杉山 将大, 韮澤 崇, Jean-Paul Duong Van Huyen, Marion Rabant, Patrick Bruneval, 内木 宏延, 湊谷 謙司, 植田 初江, 池川 雅哉
    • Organizer
      第42回心筋生検研究会学術集会
    • Data Source
      KAKENHI-PROJECT-21K06967
  • [Presentation] Ai研究を基盤に確立した推定法を用いた肝重量の経時的解析2021

    • Author(s)
      宇野 美雪, 西島 昭彦, 法木 左近, 後藤 伸之, 内木 宏延, 稲井 邦博
    • Organizer
      第19回オートプシー・イメージング(Ai)学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K06967
  • [Presentation] 心アミロイドーシスの病理組織学的診断:免疫染色の重要性とアミロイドーシスに関する調査研究班のコンサルテーション体制について2021

    • Author(s)
      内木 宏延
    • Organizer
      第42回心筋生検研究会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06967
  • [Presentation] 脳アミロイドアンギオパチーを抑制する細胞外シャペロン-In vitroモデルからの提案2019

    • Author(s)
      遠藤 芳徳, 長谷川 一浩, 野村 寮, 有島 英孝, 菊田 健一郎, 山下 太郎, 井上 泰輝, 植田 光晴, 安東 由喜雄, Mark R.Wilson, 濱野 忠則, 中本 安成, 内木 宏延
    • Organizer
      第7回日本アミロイドーシス学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] 消化管に限局した原発性アミロイドーシス4症例の検討2019

    • Author(s)
      中島 真, 下田 将之, 岩男 泰, 亀山 香織, 内木 宏延, 金井 弥栄
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] 人工知能(AI)を活用した子宮頸部細胞診診断の可能性2019

    • Author(s)
      稲井 邦博, 津森 太亮, 森 正樹, 樋口 翔平, 今村 好章, 法木 左近, 平野 靖, 内木 宏延, 木戸 尚治
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] アミロイドーシス発症の分子機構と病型診断の重要性2018

    • Author(s)
      内木 宏延
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] Class I small leucine-rich proteoglycans(SLRPs) colocalize with the Aβ2M amyloid deposits: Implications for the roles of SLRP core proteins in the pathogenesis of dialysis-related amyloidosis.2018

    • Author(s)
      Yamaguchi I, Kokubo Y, Yamashita T, Ueda M, Okoshi T, Matsumine A, Ando Y, Naiki H
    • Organizer
      The XVIth International Symposium on Amyloidosis 2018 Kumamoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] 前医の死後CTを確認することの大切さ2018

    • Author(s)
      真橋 尚吾, 鈴木 史子, 山中 昭裕, 法木 左近, 小林 基弘, 稲井 邦博, 内木 宏延, 木下 一之, 坂井 豊彦, 江端 清和, 西島 昭彦, 木村 浩彦, 島田 一郎
    • Organizer
      2018年Ai冬季症例検討会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] ヒトアミロイドーシス発症の分子機構2018

    • Author(s)
      内木 宏延
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] 病型診断の重要性とアミロイドーシス調査研究班の取り組み2018

    • Author(s)
      内木 宏延
    • Organizer
      第6回日本アミロイドーシス研究会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] Latrogenic Creutzfeldt-Jakob disease related to Dura mater grafts.2017

    • Author(s)
      Yamada M, Hamaguchi H, Sakai K, Noguchi-Shinohara M, Nozaki I, Taniguchi Y, Kobayashi A, Takeuchi A, Kitamoto T, Nakamura Y, Sanjo N, Tsukamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Mizusawa H
    • Organizer
      PRION2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] Possible human-to-human transmission of cerebral β-amyloidosis via cadaveric dura mater grafting.2017

    • Author(s)
      Yamada M, Hamaguchi T, Taniguchi Y, Sakai K, Kitamoto T, Takao M, Murayama S, Iwasaki Y, Yoshida M, Shimizu H, Kakita A, Takahashi H, Suzuki H, Naiki H, Sanjo N, Mizusawa H
    • Organizer
      Alzheimer's Association International Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] 墜落死に対する受傷機転の検討2017

    • Author(s)
      真橋 尚吾, 鈴木 史子, 法木 左近, 小林 基弘, 稲井 邦博, 内木 宏延, 木下 一之, 坂井 豊彦, 江端 清和, 西島 昭彦, 木村 浩彦, 島田 一郎
    • Organizer
      第15回オートプシー・イメージング(Ai)学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] 病理解剖遺体のオートプシー・イメージングに伴うCT検査室の環境調査結果2017

    • Author(s)
      稲井 邦博, 法木 左近, 西島 昭彦, 飛田 征男, 岩崎 博道, 内木 宏延
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] Antiamyloidogenic and proamyloidogenic chaperone effects of C-reactive protein and serum amyloid P component2016

    • Author(s)
      Ozawa D, Nomura R, Mangione PP, Hasegawa K, Okoshi T, Porcari R, Bellotti V, Naiki H
    • Organizer
      The XV International Symposium on Amyloidosis
    • Place of Presentation
      Sweden
    • Year and Date
      2016-07-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26840047
  • [Presentation] C反応性蛋白質と血清アミロイドP成分の多面的シャペロン効果2016

    • Author(s)
      小澤 大作, 野村 寮, Patrizia P. Mangione, 長谷川 一浩, 大越 忠和, Riccardo Porcari, Vittorio Bellotti, 内木 宏延
    • Organizer
      第16回日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2016-06-07
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] C反応性蛋白質と血清アミロイドP成分のアミロイド線維形成抑制および促進効果2016

    • Author(s)
      小澤 大作, 野村 寮, Patrizia P. Mangione, 長谷川 一浩, 大越 忠和, Riccardo Porcari, Vittorio Bellotti, 内木 宏延
    • Organizer
      第4回日本アミロイドーシス研究会学術集会
    • Place of Presentation
      KKRホテル東京(東京)
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] アミロイド線維形成・細胞傷害の分子機構:β2-ミクログロブリンアミロイドーシスを中心に2016

    • Author(s)
      内木 宏延
    • Organizer
      第4回日本アミロイドーシス研究会学術集会
    • Place of Presentation
      KKRホテル東京(東京)
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] C反応性蛋白質と血清アミロイドP成分の多面的シャペロン効果2016

    • Author(s)
      小澤 大作, 野村 寮, Patrizia P. Mangione, 長谷川 一浩, 大越 忠和, Riccardo Porcari, Vittorio Bellotti, 内木 宏延
    • Organizer
      第16回日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場, 福岡市
    • Year and Date
      2016-06-07
    • Data Source
      KAKENHI-PROJECT-15K06965
  • [Presentation] Thioflavin T: Not an all-rounder, but a trustworthy friend for over 27 years.2016

    • Author(s)
      Naiki H
    • Organizer
      The XVth International Symposium on Amyloidosis
    • Place of Presentation
      Uppsala Consert and Congre(Sweden)
    • Year and Date
      2016-07-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] Antiamyloidogenic and proamyloidogenic chaperone effects of C-reactive protein and serum amyloid P component.2016

    • Author(s)
      Ozawa D, Nomura R, Mangione PP, Hasegawa K, Okoshi T, Porcari R, Bellotti V, Naiki H
    • Organizer
      The XVth International Symposium on Amyloidosis
    • Place of Presentation
      Uppsala Consert and Congre(Sweden)
    • Year and Date
      2016-07-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05170
  • [Presentation] C反応性蛋白質と血清アミロイドP成分の多面的シャペロン効果2016

    • Author(s)
      小澤大作,野村寮,Mangione P. Patrizia,長谷川一浩,大越忠和,Porcari Riccardo,Bellotti Vittorio,内木宏延
    • Organizer
      第16回日本蛋白質科学会
    • Place of Presentation
      福岡県
    • Year and Date
      2016-06-07
    • Data Source
      KAKENHI-PROJECT-26840047
  • [Presentation] 透析アミロイド沈着部位に共存するグリコサミノグリカン及びプロテオグリカンの検討-病理切片を用いた免疫組織化学的観察とプロテオーム解析-2015

    • Author(s)
      山口 格, 大越 忠和, 内田 研造, 田崎 雅義, 山下 太郎, 安東 由喜雄, 内木 宏延
    • Organizer
      第3回日本アミロイドーシス研究会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Presentation] 滑膜線維芽細胞に対するβ2-ミクログロブリンアミロイド線維の細胞毒性メカニズムの解析2014

    • Author(s)
      大越 忠和, 山口 格, 小澤 大作, 長谷川 一浩, 内木 宏延
    • Organizer
      第 2 回日本アミロイドーシス研究会学術集会
    • Place of Presentation
      KKRホテル東京(東京都千代田区)
    • Year and Date
      2014-08-22
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Presentation] 滑膜線維芽細胞に対するβ2-ミクログロブリンアミロイド線維の細胞毒性メカニズムの解析2014

    • Author(s)
      大越 忠和, 山口 格, 小澤 大作, 長谷川 一浩, 内木 宏延
    • Organizer
      第 2 回日本アミロイドーシス研究会学術集会
    • Place of Presentation
      KKRホテル東京 (東京都千代田区)
    • Year and Date
      2014-08-22
    • Data Source
      KAKENHI-PROJECT-24570129
  • [Presentation] 滑膜線維芽細胞に対するβ2‐ミクログロブリンアミロイド線維の細胞毒性メカニズムの解析2014

    • Author(s)
      大越忠和、山口格、長谷川一浩、小澤大作、内木宏延
    • Organizer
      第2回日本アミロイドーシス研究会
    • Place of Presentation
      KKRホテル東京(東京都千代田区)
    • Year and Date
      2014-08-22
    • Data Source
      KAKENHI-PROJECT-26860236
  • [Presentation] ヒトアミロイド線維形成・沈着の分子機構2013

    • Author(s)
      内木 宏延
    • Organizer
      第32回日本認知症学会学術集会
    • Place of Presentation
      松本, 長野県松本文化会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Presentation] β2-ミクログロブリンアミロイド線維の線維芽滑膜細胞に対する細胞毒性の検討2013

    • Author(s)
      大越 忠和, 長谷川 一浩, 小澤 大作, 内木 宏延
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌, ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-24570129
  • [Presentation] ビーズ表面に結合した細胞外マトリクス成分は、気液界面非存在下でアルツハイマー病βアミロイド線維の核形成を促進させる2013

    • Author(s)
      長谷川 一浩, 小澤 大作, 大越 忠和, 内木 宏延
    • Organizer
      日本生物物理学会第51回年会
    • Place of Presentation
      京都, 京都国際会議場
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Presentation] β2-ミクログロブリンアミロイド線維の線維芽滑膜細胞に対する細胞毒性の検討2013

    • Author(s)
      大越 忠和, 長谷川 一浩, 小澤 大作, 内木 宏延
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌, ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Presentation] ビーズ表面に結合した細胞外マトリクス成分は、気液界面非存在下でアルツハイマー病βアミロイド線維の核形成を促進させる2013

    • Author(s)
      長谷川 一浩, 小澤 大作, 大越 忠和, 内木 宏延
    • Organizer
      日本生物物理学会第51回年会
    • Place of Presentation
      京都, 京都国際会議場
    • Data Source
      KAKENHI-PROJECT-24570129
  • [Presentation] Molecular mechanisms of β2-microglobulin amyloid fibril formation2012

    • Author(s)
      Ozawa D, Hasegawa K, Ookoshi T, Naiki H
    • Organizer
      XIIIth International Symposium on Amyloidosis
    • Place of Presentation
      Groningen(the Netherlands)
    • Data Source
      KAKENHI-PROJECT-24770150
  • [Presentation] Molecular mechanisms ofβ2-microglobulin amyloid fibril formation2012

    • Author(s)
      Ozawa D, Hasegawa K, Ookoshi T, Naiki H
    • Organizer
      XIIIth International Symposium on Amyloidosis
    • Place of Presentation
      Groningen, the Netherlands (口頭発表およびポスター発表)
    • Data Source
      KAKENHI-PROJECT-24770150
  • [Presentation] 細胞外シャペロンによるアミロイド線維形成抑制機構の解明2012

    • Author(s)
      小澤大作, 長谷川一浩, 李 映昊, 櫻井一正, 柳 浩太郎, 大越忠和, 後藤祐児, 内木宏延
    • Organizer
      第12回日本蛋白質科学会年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24570129
  • [Presentation] アミロイド線維形成・沈着の分子機構2012

    • Author(s)
      内木宏延
    • Organizer
      第58回日本病理学会総会秋季特別総会(ヒトの疾患解明に直結した最新の病理学研究)
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] Molecular mechanisms of β2-microglobulin amyloid fibril formation.2012

    • Author(s)
      Ozawa D, Hasegawa K, Ookoshi T, Naiki H
    • Organizer
      XIIIth International Symposium on Amyloidosis
    • Place of Presentation
      Groningen(the Netherlands)
    • Data Source
      KAKENHI-PROJECT-24570129
  • [Presentation] マウス F 型 apoA-II の C 末ペプチドは老化アミロイドーシス高発症マウスのアミロイド沈着を軽減する2012

    • Author(s)
      澤下仁子, 張 〓茄, 亀谷富由樹, 長谷川一浩, 森 政之, 内木宏延, 樋口京一
    • Organizer
      第27回老化促進モデルマウス(SAM)研究協議会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] Molecular mechanisms of β2-microglobulin amyloid fibril formation2012

    • Author(s)
      Ozawa D, Hasegawa K, Ookoshi T, NaikiH
    • Organizer
      XIII^<th>International Symposium on Amyloidosis
    • Place of Presentation
      Groningen(the Netherlands)
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] アミロイド線維形成・沈着の分子機構2012

    • Author(s)
      内木宏延
    • Organizer
      第58回日本病理学会総会秋季特別総会(ヒトの疾患解明に直結した最新の病理学研究)
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 細胞外シャペロンによるアミロイド線維形成抑制機構の解明2012

    • Author(s)
      小澤大作, 長谷川一浩, 李 映昊, 櫻井一正, 柳 浩太郎, 大越忠和, 後藤祐児, 内木宏延
    • Organizer
      第12回日本蛋白質科学会年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24770150
  • [Presentation] 細胞外シャペロンによるアミロイド線維形成抑制機構の解明2012

    • Author(s)
      小澤大作, 長谷川一浩, 李 映昊, 櫻井一正, 柳 浩太郎, 大越忠和, 後藤祐児, 内木宏延
    • Organizer
      第12回日本蛋白質科学会年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 蛍光色素チオフラビン T とレーザー光によるアミロイド線維の分解.2011

    • Author(s)
      小澤大作, 加治優一, 八木寿梓 櫻井一正, 川上 徹, 内木宏延, 後藤祐児
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 溶液 NMR による β2 ミクログロブリンアミロイド線維形成のモノマー-線維核相互作用機構の解明2011

    • Author(s)
      櫻井一正, 柳 浩太郎, 吉村優一, 小沼剛, 菅瀬謙治, 池上貴久, 内木宏延, 後藤祐児
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      吹田
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] β2-ミクログロブリンアミロイド線維形成・沈着の分子機構2011

    • Author(s)
      内木宏延
    • Organizer
      第56回日本透析医学会学術集会・総会
    • Place of Presentation
      横浜(招待講演)
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] チオフラビン T とレーザー光を利用したアミロイド線維の分解2011

    • Author(s)
      小澤大作, 加治優一, 八木寿梓, 櫻井一正, 川上 徹, 内木宏延, 後藤祐児
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      吹田
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 伸長反応中間体の観察によるアミロイド構造伝播機構の解明2011

    • Author(s)
      茶谷絵理, 小沼 剛, 大西玲奈, 八木正典, 櫻井一正, 池上貴久, 内木宏延, 後藤祐児
    • Organizer
      第11回日本蛋白質科学会年会(蛋白質のフォールディングと異常凝集の統一原理)
    • Place of Presentation
      吹田
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] β2-ミクログロブリンアミロイド線維形成・沈着の分子機構2011

    • Author(s)
      内木宏延
    • Organizer
      第56回日本透析医学会学術集会・総会(透析アミロイドーシス UpDate)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 超音波によるアミロイド線維形成促進2011

    • Author(s)
      宗 正智, 八木寿梓, 櫻井一正, 荻 博次, 内木宏延, 後藤祐児
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      吹田
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 超音波による amyloid β(1-40)の線維形成機構.2011

    • Author(s)
      長谷川恭平, 八木寿梓, 志鷹裕司, 内木宏延, 後藤祐児
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] β2-ミクログロブリンアミロイド線維形成・沈着の分子機構2011

    • Author(s)
      内木宏延
    • Organizer
      第56回日本透析医学会学術集会・総会
    • Place of Presentation
      横浜(招待講演)
    • Data Source
      KAKENHI-PUBLICLY-22020014
  • [Presentation] 超音波処理下で作製した微細アミロイド線維の構造および物性のキャラクタリゼーション2011

    • Author(s)
      吉村優一, 櫻井一正, 八木寿梓, 宗 正智, 李 映昊, 荻 博次, 内木宏延, 後藤祐児
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      吹田
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 気液界面の影響を排除したアルツハイマー病 β アミロイド線維の核形成検出系の開発2011

    • Author(s)
      長谷川一浩, 内木宏延
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] α_2-Macroglobulin inhibits β_2-microglobulin amyloid fibril formation in vitro2010

    • Author(s)
      Ozawa D, Hasegawa K, Lee YH, Sakurai K, Yanagi K, Ookoshi T, Goto Y, Naiki H
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] Transmissible amyloid fibrils formed by selective N-, C-terminal sequences of mouse apolipoprotein A-II2010

    • Author(s)
      Sawashita J, Kametani F, Hasegawa K, Mori M, Naiki H, Higuchi K
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      Nara
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] a_2-Macroglobulin inhibits β_2-microglobulin amyloid fibril formation in vitro.2010

    • Author(s)
      Ozawa D., Hasegawa K., Lee YH., Sakurai K., Yanagi K., Ookoshi T., Goto Y., Naiki H.
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      Nara.
    • Year and Date
      2010-09-13
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Presentation] レーザー照射によるアミロイド線維の増殖と崩壊2010

    • Author(s)
      八木寿梓, 小澤大作, 櫻井一正, 加治優一, 川上 徹, 九山浩樹, 内木宏延, 後藤祐児
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] Direct observation of minimum-sized amyloid fibrils using solution NMR spectroscopy2010

    • Author(s)
      Yoshimura Y, Sakurai K, Lee YH, Ikegami T, Chatani E, Naiki H, Goto Y
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      Nara
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] α_2-Macroglobulin inhibits β_2-microglobulin amyloid fibril formation in vitro.2010

    • Author(s)
      Ozawa D, Hasegawa K, Lee YH, Sakurai K, Yanagi K, Ookoshi T, Goto Y, Naiki H
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      Nara
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 超音波による K3 peptide と α-synuclein のアミロイド線維形成2010

    • Author(s)
      水野愛子, 宗 正智, 八木寿梓, 櫻井一正, 河田康志, 内木宏延, 後藤祐児
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] Molecular pathogenesis of β_2-microglobulin-related amyloidosis : The past, the present and the future2010

    • Author(s)
      Naiki, H.
    • Organizer
      International Symposium on Amyloidogenesis and Anti-Amyloid Therapies
    • Place of Presentation
      Tokyo
    • Year and Date
      2010-01-28
    • Data Source
      KAKENHI-PROJECT-20059015
  • [Presentation] β_2-ミクログロブリンが形成するアミロイド線維の溶液 NMR による直接観察2010

    • Author(s)
      吉村優一, 櫻井一正, 李 映昊, 池上貴久, 茶谷絵理, 内木宏延, 後藤祐児
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] 超音波による超高速アミロイド線維形成反応2010

    • Author(s)
      宗 正智, 八木寿梓, 櫻井一正, 内木宏延, 後藤祐児
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] マウスF型apolipoprotein A-II(apoA-II)のC末アミノ酸配列はアミロイド線維形成を阻止する2010

    • Author(s)
      澤下仁子、亀谷富由樹、長谷川 一浩、 張〓茄、王耀勇、森政之、 内木延、樋口京一
    • Organizer
      日本基礎老化学会第33回大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Presentation] Laser-induced propagation and destruction of amyloid β fibrils2010

    • Author(s)
      Yagi H, Ozawa D, Sakurai K, Naiki H, Goto Y
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      Nara
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] パルスラベル H/D 交換法と NMR を用いた β2ミクログロブリンの線維伸長中間体の解析2010

    • Author(s)
      小沼 剛, 茶谷絵理, 八木正典, 櫻井一正, 池上貴久, 内木宏延, 後藤祐児
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] β アミロイド線維の核形成における界面の影響2010

    • Author(s)
      長谷川一浩, 森永章義, 山田正仁, 内木宏延
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22390075
  • [Presentation] The role of interfaces and agitation on the fibril formation of amyloid β-protein.2010

    • Author(s)
      Morinaga A, Hasegawa K, Nomura R, Ookoshi T, Ozawa D, Goto Y, Yamada M, Naiki H.
    • Organizer
      Alzheimer's Association International Conference on Alzheimer's Disease 2010
    • Place of Presentation
      Hawaii.
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Presentation] βアミロイド線維の核形成における界面の影響2010

    • Author(s)
      長谷川一浩、森永章義、山田正仁、内木宏延
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Presentation] 遊離脂肪酸によるβ2-ミクログロブリンアミロイド線維伸長反応促進効果の解析2009

    • Author(s)
      大越忠和、長谷川一浩、後藤祐児、内木宏延
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Presentation] アミロイド線維形成の重合核依存性重合モデルと線維形成阻害薬の探索2009

    • Author(s)
      内木宏延, 長谷川一浩, 小野賢二郎, 山田正仁
    • Organizer
      日本薬学会第129年会シンポジウム(S-22)「アミロイドβペプチドの凝集・毒性発現の分子メカニズムの解明と低分子化合物による阻害 : アルツハイマー病の克服に向けて」
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Presentation] アミロイド線維形成の重合核依存性重合モデルと線維形成阻害薬の探索2009

    • Author(s)
      内木宏延, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Presentation] 透析アミロイドーシス発症における血漿リゾリン脂質濃度の意義2009

    • Author(s)
      高橋直生、木村秀樹、大越忠和、長谷川 一浩、奈良雅文、宮崎良一、内木宏延、吉田治義
    • Organizer
      第52回平成21年度日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20570105
  • [Presentation] アミロイド線維形成・沈着の分子機構-β2-ミクログロブリンアミロイド線維を中心に-2009

    • Author(s)
      内木宏延
    • Organizer
      第60回日本電気泳動学会総会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-20059015
  • [Presentation] アミロイド線維形成の重合核依存性重合モデルと線維形成阻害薬の探索2009

    • Author(s)
      内木宏延, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20059015
  • [Presentation] アミロイド線維形成・沈着の分子機構-ALアミロイドーシスを中心に-2008

    • Author(s)
      内木宏延
    • Organizer
      第9回東京腎炎・ネフローゼ研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Presentation] ヒトアミロイドーシスの分子病態解明に向けて2008

    • Author(s)
      内木宏延
    • Organizer
      日本ヒトプロテオーム機構第6回大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Presentation] アミロイド線維形成・沈着の分子機構-ALアミロイドーシスを中心に-2008

    • Author(s)
      内木宏延
    • Organizer
      第9回東京腎炎・ネフローゼ研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-20059015
  • [Presentation] ヒトアミロイドーシスの分子病態解明に向けて2008

    • Author(s)
      内木宏延
    • Organizer
      日本ヒトプロテオーム機構第6回大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20059015
  • [Presentation] ヒトアミロイドーシスの分子病態解明に向けて : 現状と展望2008

    • Author(s)
      内木宏延
    • Organizer
      第8回日本蛋白質科学会年会シンポジウム「アミロイド構造生物学の新たな地平」
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Presentation] ヒトアミロイドーシスの分子病態解明に向けて2008

    • Author(s)
      内木宏延
    • Organizer
      日本ヒトプロテオーム機構第6回大会シンポジウム「蛋白質のフォールディング病」
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Presentation] ヒトアミロイドーシスの分子病態解明に向けて : 現状と展望2008

    • Author(s)
      内木宏延
    • Organizer
      第8回日本蛋白質科学会年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Presentation] Molecular pathogenesis of β2-microglobulin-related amyloidosis2006

    • Author(s)
      Naiki, H.
    • Organizer
      24th Annual Meeting of the International Society of Blood Purification
    • Place of Presentation
      Nara, Japan
    • Data Source
      KAKENHI-PROJECT-18390120
  • [Presentation] Double tracer autoradiography with FDG/Cu-ATSM and immunohistochemical interpretation in 4 different mouse implanted tumor models2005

    • Author(s)
      Tanaka T, Furukawa T, Kasamatsu S, Takamatsu S, Sunaga H, Fujieda S, Naiki H, Yonekura Y, Fujibayashi Y.
    • Organizer
      Society of Nuclear Medicine 52 and Annual Meeting
    • Place of Presentation
      Toronto, Canada
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591260
  • [Presentation] Double tracer autoradiography with FDG/Cu-ATSM and immunohistochemical interpretation in 4 different mouse inplanted tumor models2005

    • Author(s)
      Tanaka T, Furukawa T, Kasamatsu S, Takamatsu S, Sunaga H, Fujieda S, Naiki H, Yonekura Y, Fujibayashi Y.
    • Organizer
      Society of Nuclear Medicine 52nd Annual Meeting
    • Place of Presentation
      Tronto, Canada
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591260
  • [Presentation] β2-ミクログロブリンアミロイド線維は滑膜線維芽細胞内に取り込まれ毒性を発揮する-形態解析を中心に-

    • Author(s)
      大越 忠和, 長谷川 一浩, 小澤 大作, 内木 宏延
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場 (広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-24570129
  • [Presentation] A novel cytotoxic mechanism of amyloid fibrils: Endocytosis-dependent necrosis and apoptosis of rabbit synovial fibroblasts by β2-microglobulin amyloid fibrils

    • Author(s)
      T.Ookoshi, D.Ozawa, K.Hasegawa, H.Naiki
    • Organizer
      XIVth International Symposium on Amyloidosis
    • Place of Presentation
      Indianapolis, Indiana, USA JW Marriott Down
    • Year and Date
      2014-04-27 – 2014-05-01
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Presentation] A novel cytotoxic mechanism of amyloid fibrils: Endocytosis-dependent necrosis and apoptosis of rabbit synovial fibroblasts by β2-microglobulin amyloid fibrils.

    • Author(s)
      T.Ookoshi, D.Ozawa, K.Hasegawa, H.Naiki
    • Organizer
      XIVth International Symposium on Amyloidosis
    • Place of Presentation
      Indianapolis (USA)
    • Year and Date
      2014-04-27 – 2014-05-01
    • Data Source
      KAKENHI-PROJECT-24570129
  • [Presentation] Molecular pathogenesis of amyloid fibril formation and deposition

    • Author(s)
      H.Naiki
    • Organizer
      JSPS Japan Hungary Joint Seminar
    • Place of Presentation
      大阪大学蛋白質研究所(大阪府吹田市)
    • Year and Date
      2014-11-18 – 2014-11-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293094
  • [Presentation] β2-ミクログロブリンアミロイド線維は滑膜線維芽細胞内に取り込まれ毒性を発揮する-形態解析を中心に-

    • Author(s)
      大越 忠和, 長谷川 一浩, 小澤 大作, 内木 宏延
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25293094
  • 1.  HASEGAWA Kazuhiro (60324159)
    # of Collaborated Projects: 26 results
    # of Collaborated Products: 71 results
  • 2.  OOKOSHI Tadakazu (90362037)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 43 results
  • 3.  HIGUCH Keiichi (20173156)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 8 results
  • 4.  OZAWA Daisaku (60554524)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 39 results
  • 5.  GOTO Yuji (40153770)
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  • 6.  MORI Masayuki (60273190)
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  • 7.  YAMADA Masahito (80191336)
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  • 13.  MAEDA Shuichiro (10117244)
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  • 15.  SAKURAI Kazumasa (10403015)
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  • 16.  FUJIWARA Toshimichi (20242381)
    # of Collaborated Projects: 1 results
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  • 17.  CHATANI Eri (00432493)
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  • 18.  HAMANO TADANORI (40334817)
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  • 19.  Shirafuji Norimichi (40529319)
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  • 20.  HOSONO Masamichi (90107433)
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  • 21.  HOSHINO Masaru (70304053)
    # of Collaborated Projects: 1 results
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  • 22.  INAI Kunihiro (30313745)
    # of Collaborated Projects: 1 results
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  • 23.  NORIKI Sakon (30228374)
    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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  • 25.  FUJIBAYASHI Yasuhisa (50165411)
    # of Collaborated Projects: 1 results
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  • 26.  FUJIEDA Shigeharu (30238539)
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  • 27.  今野 卓 (50225637)
    # of Collaborated Projects: 1 results
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  • 28.  清野 泰 (50305603)
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  • 37.  SEKIJIMA Yoshiki
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  • 38.  TSUKIMURA Takahiro
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  • 39.  MORI Kentaro
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  • 40.  TAKAHASHI Takashi
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  • 41.  KITA Yoshikuni
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  • 42.  KAMETANI Kiyokazu
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  • 43.  MIYAGAWA Aya
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  • 44.  安東 由喜雄
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  • 45.  定 清直
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  • 46.  菅井 学
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  • 47.  成田 一衛
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  • 48.  北本 哲之
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  • 49.  高尾 昌樹
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  • 51.  岩崎 靖
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  • 52.  鈴木 貞夫
    # of Collaborated Projects: 0 results
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  • 53.  清水 厚志
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  • 54.  鈴木 康司
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  • 55.  村山 繁雄
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  • 56.  徳力 周子
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  • 57.  河北 亜希子
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  • 58.  大嶋 勇成
    # of Collaborated Projects: 0 results
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  • 59.  山下 太郎
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  • 60.  井上 泰輝
    # of Collaborated Projects: 0 results
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  • 61.  浜野 忠則
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  • 62.  飯野 哲
    # of Collaborated Projects: 0 results
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  • 63.  菊田 健一郎
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  • 64.  八木 寿梓
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  • 65.  李 映昊
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    # of Collaborated Projects: 0 results
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  • 67.  笹原 健二
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    # of Collaborated Products: 3 results
  • 68.  宗 正智
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  • 69.  野阪 拓人
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    # of Collaborated Products: 1 results

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