TAMURA Akira 田村明

Researcher Number	00375023
Affiliation (based on the past Project Information) *help	2006: Tohoku University, Hospital, Research Associate, 病院, 助手 2004 – 2006: 東北大学, 病院・医員 2005: 東北大学, 病院, 医員
Review Section/Research Field	Principal Investigator Metabolomics Except Principal Investigator Metabolomics / Pathological medical chemistry
Keywords	Principal Investigator Gene knockdown / Liver / Insulin / Nitric Oxide / Parasympatic nerve / Urotensin II / Diabetes / 遺伝子ノックダウン / 肝臓 / インスリン … More / 一酸化窒素 / 副交感神経 / ウロテンシンII / 糖尿病 … More Except Principal Investigator インスリン分泌 / 糖尿病 / 小胞体ストレス / 膵ラ島 / Signal Transduction / Pancreatic Islet / Diabetes Mellitus / 分子生物学 / カルシウム / マイクロアレイ / アポトーシス / グルカゴン分泌 / 膵ランゲルハンス島 / シグナル伝達 / 膵島 / endoplasmic reticulum stress / pancreatic β cell / insulin secretion / 小胞体カルシウム / WFS1 / 膵β細胞 / 頚動脈弾性特性 / 電子的染色法 / 動脈硬化症 / 位相差トラッキング法 / グリセロールキナーゼ / ジカルボン酸輸送担体 / グルカゴン Less

動脈硬化早期診断法の確立-血管壁の電子的染色法を用いて
- Principal Investigator
  
  岡芳知
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Molecular mechanisms for pancreatic beta cell failure・a viewpoint from endoplasmic reticulum stress
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Molecular Mechanisms for Pancreatic Islet Disfunction in Development of Diabetes Mellitus-a study using WFS1 knockout mice
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Signaling axis of urotensin II, parasympathetic nerves, and nitric oxide on carbohydrate metabolism: A clinicalPrincipal Investigator
- Principal Investigator
  
  TAMURA Akira
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
転写ターゲティングシステム構築による膵島ホルモン分泌制御機構の解析と遺伝子治療
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University

All 2007 2006 2005 2004

All Journal Article

[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, Takahashi K, Tamura A, Yamaguchi S, Yamada T, Katagiri H, Oka Y.
- Journal Title
  
  J Mol Endocrinol 38・1-2
  
  Pages: 127-136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, Takahashi K, Tamura A, Yamaguchi S, Yamada T, Katagiri H, Oka Y
- Journal Title
  
  J Mol Endocrinol 38・1-2
  
  Pages: 127-136
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] WFS1-deficiency enhances endoplasmic reticulum stress, triggers apoptotic pathway and impairs cell cycle progression specifically in pancreatic 13-cells.2006
- Author(s)
  Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki J-I, Oka Y.
- Journal Title
  
  Hum Mol Genet 15・10
  
  Pages: 1600-1609
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, Tamura A, Yamaguchi S, Yamada T, Takei D, Katagiri H, Endou H, Oka Y.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, Yamaguchi S, Yamada T, Tamura A, Katagiri H, Maruyama Y, Oka Y
- Journal Title
  
  FEBS Lett 580・24
  
  Pages: 5635-5640
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, Yamaguchi S, Yamada T, Tamura A, Katagiri H, Maruyama Y, Oka Y
- Journal Title
  
  FEBS Lett 580.24
  
  Pages: 5635-5640
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Hypoglycemia associated with hyperinsulinemia in a subject with type 2 diabetes and liver cirrhosis.2006
- Author(s)
  Tamura A, Ishihara H, et al.
- Journal Title
  
  Nippon Naika Gakkai Zasshi 95.7
  
  Pages: 1371-1374
- NAID
  10018198589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] WFS1-deficiency enhances endoplasmic reticulum stress, triggers apoptotic pathway and impairs cell cycle progression specifically in pancreatic β-cells.2006
- Author(s)
  Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki J-I, Oka Y
- Journal Title
  
  Hum Mol Genet 15・10
  
  Pages: 1600-1609
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, Yamaguchi S, Yamada T, Tamura A, Katagiri H, Maruyama Y, Oka Y.
- Journal Title
  
  FEBS Lett 580・24
  
  Pages: 5635-5640
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Hypoglycemia associated with hyperinsulinemia in a subject with type 2 diabetes and liver cirrhosis.2006
- Author(s)
  Tamura A, Ishihara H, et al.
- Journal Title
  
  Nippon Naika Gakkai Zasshi 95・7
  
  Pages: 1371-1374
- NAID
  10018198589
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Hypoglycemia associated with hyperinsulinemia in a subject with type 2 diabetes mellitus and liver cirrhosis2006
- Author(s)
  Akira Tamura
- Journal Title
  
  Nippon Naika Gakkai Zasshi. 95
  
  Pages: 1371-1374
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590264
[Journal Article] Hypoglycemia associated with hyperinsulinemia in a subject with type 2 diabetes mellitus and liver cirrhosis2006
- Author(s)
  Akira Tamura
- Journal Title
  
  Nippon Naika Gakkai Zasshi 95
  
  Pages: 1371-1374
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590264
[Journal Article] Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population.2005
- Author(s)
  Iwasaki N, Horikawa Y, Tsuchiya T, Kitamura Y, Takahiro Nakamura, Tanizawa Y, Oka Y, et al.
- Journal Title
  
  J Hum Genet. 50・2
  
  Pages: 92-98
- NAID
  10014513339
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein2004
- Author(s)
  Yamaguchi S, Ishihara H, Tamura A, Yamada T, Takahashi R, Takei D, Katagiri H, Oka Y.
- Journal Title
  
  Biochem Biophys Res Commun 325
  
  Pages: 250-256
- Data Source
  KAKENHI-PROJECT-15659213
[Journal Article] Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.2004
- Author(s)
  Ishihara H, Takeda S, Tamura A, Takahashi R, Yamaguchi S, Takei D, Yamada T, Inoue H, Soga H, Katagiri H, Tanizawa Y, Oka Y.
- Journal Title
  
  Hum Mol Genet 13
  
  Pages: 1159-1170
- Data Source
  KAKENHI-PROJECT-15659213

1. ISHIHARA Hisamitsu (60361086)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. OKA Yoshitomo (70175256)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. ISHIGAKI Yasushi (50375002)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OGIHARA Takehide (40361068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HINOKIO Yoshinori (10282071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUZUKI Susumu (70216399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 高橋和眞 (60292215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAMURA Akira 田村 明

Research Projects

Research Products

Co-Researchers

動脈硬化早期診断法の確立-血管壁の電子的染色法を用いて

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms for pancreatic beta cell failure・a viewpoint from endoplasmic reticulum stress

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Mechanisms for Pancreatic Islet Disfunction in Development of Diabetes Mellitus-a study using WFS1 knockout mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Signaling axis of urotensin II, parasympathetic nerves, and nitric oxide on carbohydrate metabolism: A clinicalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写ターゲティングシステム構築による膵島ホルモン分泌制御機構の解析と遺伝子治療

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007

Author(s)

Journal Title

Data Source

[Journal Article] WFS1-deficiency enhances endoplasmic reticulum stress, triggers apoptotic pathway and impairs cell cycle progression specifically in pancreatic 13-cells.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006

Author(s)

Journal Title

Data Source

[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006

Author(s)

Journal Title

Data Source

[Journal Article] Hypoglycemia associated with hyperinsulinemia in a subject with type 2 diabetes and liver cirrhosis.2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] WFS1-deficiency enhances endoplasmic reticulum stress, triggers apoptotic pathway and impairs cell cycle progression specifically in pancreatic β-cells.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Hypoglycemia associated with hyperinsulinemia in a subject with type 2 diabetes and liver cirrhosis.2006

Author(s)

Journal Title

TAMURA Akira 田村明