SUZUKI Susumu 鈴木進

Researcher Number	70216399
Affiliation (based on the past Project Information) *help	2006: Tohoku University, Graduate School of Medicine, Lecturer, 大学院医学系研究科, 講師 2005: 東北大学, 大学院医学系研究科, 助教授 2003 – 2005: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 2002: Tohoku University Hospital, Lecture, 医学部附属病院, 講師 1999 – 2002: 東北大学, 医学部・附属病院, 講師 … More 1998: 東北大学, 医学部附属病院, 助手 1997 – 1998: 東北大学, 医学部・附属病院, 助手 1996: 東北大学, 医学部・付属病院, 助手 1995: 東北大学, 医学部・附属病院, 助手 1994: 東北大学, 医学部附属病院, 助手 1992: TOHOKU UNIVERSITY ASSISTANT PROFESSOR, 歯学部, 助手 1991 – 1992: 東北大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator 内分泌・代謝学 / Metabolomics / Metabolomics Except Principal Investigator 内分泌・代謝学 / Metabolomics / Metabolomics / Morphological basic dentistry
Keywords	Principal Investigator 糖尿病 / インスリン抵抗性 / インスリン / ミトコンドリアDNA / 酸化ストレス / 糖尿病性腎症 / 糖尿病性網膜症 / DNA損傷 / Oxidative stress / GC-MS … More / ガングリオシド / シアリダーゼ / インスリン受容体 / インスリン受容体基質1 / 糖尿病性合併症 / ミトコンドリア遺伝子 / DNA欠失 / 脂肪肝 / うつ病 / ベンゾジアゼピン受容体 / ミトコンドリア / 一塩基置換修復法 / Chimeric RNA / DNA / 膵ラ島β細胞 / ガングリオシド抗体 / アポトーシス / 8-hydroxydeoxyguanosine / 8-oxo-2'-deoxyguanosine / mitochondrial DNA / diabetic nephropathy / diabetic retinopathy / 糖尿病合併症 / 酸化的DNA損傷 / 8-oxo-deoxyguanosive / 8-OXO-deoxyguanosine / 活性酸素 / Diabetes mellitus / Diabetic complication / Diabetic nephropathy / Diabetic retinopathy / Oxidative DNA damage / 8-oxo-deoxyguanosine / トラスジェニックマウス / ノックアウトマウス / タンスジェニックマウス / Diabetes / Ganglioside / Sialidase / Insulin resistance / Transgenic mice / Knockout mice / Insulin receptor / Insulin receptor substrate 1 / アデノウイルスベクター / 耐糖能 / diabetes / ganglioside / sialidase / adenovirus vector / glucose tolerance / insulin resistance / insulin receptor / insulin receptor substrate 1 … More Except Principal Investigator HNF / インスリン抵抗性 / インスリン非依存性糖尿病 / 糖尿病 / 2型糖尿病 / インスリン / 分子生物学 / MODY / type 2 diabetes / PIGA遺伝子 / インスリン受容体 / 血管内皮細胞 / Caveolae / Transcytosis / 歯肉 / HSV1型 / 感染 / 腹腔 / TcRγδ細胞 / Vβ11^+αβ細胞 / 毒性 / HSV-1型 / ヘルペスウイルス / 禁止クロ-ン / 免疫 / 口腔感染 / 口腔免疫 / Gingiva / HSV type 1 / Infection / Intraperitoneal cavity / TcRgamma delta cells / Vbeta11^+alphabetacells / Virulence / gene mutations / GPI特異的フォスフォリパーゼD / インスリン分泌不全 / イノシトールグリカン / Type 2 diabetes mellitus / GPI specific phospholipase D / impairment of insulin secretion / insulin resistance / inositol glycan / 転写因子 / 酸化ストレス / 若年発症糖尿病 / フォークヘッドファミリー / transcription factor / oxidative stress / ウロテンシンII / 副交感神経 / 一酸化窒素 / 肝臓 / 遺伝子ノックダウン / Diabetes / Urotensin II / Parasympatic nerve / Nitric Oxide / Insulin / Liver / Gene knockdown Less

Signaling axis of urotensin II, parasympathetic nerves, and nitric oxide on carbohydrate metabolism: A clinical
- Principal Investigator
  
  TAMURA Akira
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
膵ラ島β細胞ミトコンドリアを標的とする遺伝子治療の開発Principal Investigator
- Principal Investigator
  
  鈴木進
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Elucidation of abnormality of plasma membrane microdomain in type 2 diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  SUZUKI Susumu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
The role of genes of forkhead transcription factors in type2 diabetes and obesity.
- Principal Investigator
  
  HINOKIO Yoshinori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
The role of plasma membrane type sialidase gene Neu3 on the pathogenesis of type 2 diabetes mellitusin Japanese.Principal Investigator
- Principal Investigator
  
  SUZUKI Susumu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
The role of phospholipase D in the development of diabetes mellitus
- Principal Investigator
  
  HIRAI Masashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  TOHOKU UNIVERSITY
The cascade of hepatocyte nuclear factor in early-onset diabetes.
- Principal Investigator
  
  HINOKIO Yoshinori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Development of a new assay method for oxidative DNA damages in diabetesPrincipal Investigator
- Principal Investigator
  
  SUZUKI Susumu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
The HNF-related transcription cascade in maturity-onset diabetes of the young.
- Principal Investigator
  
  HINOKIO Yoshinori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Role of oxidative DNA damage in the pathogenesis of diabetic complicationsPrincipal Investigator
- Principal Investigator
  
  SUZUKI Susumu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tohoku University
インスリン抵抗性症候群における血管内皮細胞インスリン転送異常の分子機序
- Principal Investigator
  
  豊田隆謙
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tohoku University
NIDDMにおけるCaveolae型インスリンシグナル複合体機能異常の分子機序
- Principal Investigator
  
  豊田隆謙
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tohoku University
NIDDMにおける末梢型ベンゾジアゼピン受容体機能異常の分子生物学的検討Principal Investigator
- Principal Investigator
  
  鈴木進
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tohoku University
インスリン抵抗性症候群の成因としてのPIGA遺伝子異常の解明
- Principal Investigator
  
  豊田隆謙
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tohoku University
糖尿病性慢性合併症の発症,進展に関与するミトコンドリア遺伝子異常の解明Principal Investigator
- Principal Investigator
  
  鈴木進
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Tohoku University
RECOVERY FROM A LETHAL INFECTION WITH HSV : ROLE OF gamma deltaT CELLS AND ANALYSIS OF ORAL DEFENSE MECHANISM
- Principal Investigator
  
  SHIMIZU Fumio
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  NIPPON DENTAL UNIVERSITY
  Tohoku University

All 2007 2005 2004 Other

All Journal Article

[Journal Article] Increased hepatic expression of ganglioside-specific sialidase, NEU3, improves insulin sensitivity and glucose tolerance in mice.2007
- Author(s)
  Yoshizumi S, Suzuki S, et al.
- Journal Title
  
  Metabolism 56・3
  
  Pages: 420-439
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Genetic variations of urotensin II gene in type 2 diabetes2005
- Author(s)
  Hinokio Y, Suzuki S, Oka Y.
- Journal Title
  
  Nippon Rinsho 63
  
  Pages: 193-197
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.2005
- Author(s)
  Hirai M, Suzuki S, Hinokio Y, Yamada T, et al.
- Journal Title
  
  Diabetes Res Clin Pract. 69・3
  
  Pages: 287-292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390259
[Journal Article] WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.2005
- Author(s)
  Hirai M, Suzuki S, Hinokio Y, Yamada T, et al.
- Journal Title
  
  Diabetes Res Clin Pract 69・3
  
  Pages: 287-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390259
[Journal Article] WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.2005
- Author(s)
  Hirai M, Suzuki S, Hinokio Y, Yamada T, Yoshizumi S, Suzuki C, Satoh J, Oka Y.
- Journal Title
  
  Diabetes Res Clin Pract. 69
  
  Pages: 287-292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.2005
- Author(s)
  Hirai M, Suzuki S, Hinokio Y, Yamada T, Yoshizumi S, Suzuki C, Satoh J, Oka Y.
- Journal Title
  
  Diabetes Res Clin Pract 69
  
  Pages: 287-292
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.2005
- Author(s)
  Hirai M, Suzuki S, Hinokio Y, et al.
- Journal Title
  
  Diabetes Res Clin Pract 69・3
  
  Pages: 287-292
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.2005
- Author(s)
  Hirai M, Suzuki S, Hinokio Y, et al.
- Journal Title
  
  Diabetes Res Clin Pract 69・3
  
  Pages: 287-292
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Secondary sulfonylurea failure : comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide.2005
- Author(s)
  Satoh J, Takahashi K, Takizawa Y, Ishihara H, Hirai M, Katagiri H, Hinokio Y, Suzuki S, Tsuji I, Oka Y.
- Journal Title
  
  Diabetes Res Clin Pract 70
  
  Pages: 291-297
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] Genetic variations of urotensin II gene in type 2 diabetes2005
- Author(s)
  Hinokio Y, Suzuki S, Oka Y.
- Journal Title
  
  Nippon Rinsho. 63
  
  Pages: 193-197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] Secondary sulfonylurea failure : comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide.2005
- Author(s)
  Satoh J, Takahashi K, Takizawa Y, Ishihara H, Hirai M, Katagiri H, Hinokio Y, Suzuki S, Tsuji I, Oka Y.
- Journal Title
  
  Diabetes Res Clin Pract. 70
  
  Pages: 291-297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] Genetic Variations at Urotensin II and Urotensin II Receptor Genes and Risk of Type 2 Diabetes Mellitus in Japanese.2004
- Author(s)
  Suzuki S, Wenyi Z, Hirai M, Hinokio Y, Suzuki C, et al.
- Journal Title
  
  Peptide 25
  
  Pages: 1801-1808
- Data Source
  KAKENHI-PROJECT-16390259
[Journal Article] Diabetes mellitus with mitochondrial gene mutations in Japan.2004
- Author(s)
  Suzuki S
- Journal Title
  
  Ann N Y Acad Sci 1011
  
  Pages: 185-192
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Premoter polymorphism of SLC11A1 (formerly NRAMP1) confers susceptibility to autoimmune type 1 diabetes mellitus in Japanese.2004
- Author(s)
  Takahashi K, Satoh J, Kojima Y, Negoro K, Hirai M, Hinokio Y, Kinouchi Y, Suzuki S, Matsuura N, Shimosegawa T, Oka Y
- Journal Title
  
  Tissue Antigens 63
  
  Pages: 231-236
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] Genetic variations at urotensin II and urotensin II receptor genes and risk of type 2 diabetes mellitus in Japanese.2004
- Author(s)
  Suzuki S, Zong Wenyi, Hirai M, Hinokio Y, Suzuki C, Yamada T, Yoshizumi S, Suzuki M, Tanizawa Y, Matsunami A, Oka Y
- Journal Title
  
  Peptides 25
  
  Pages: 1803-1808
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] Genetic Variations at Urotensin II and Urotensin II Receptor Genes and Risk of Type 2 Diabetes Mellitus in Japanese.2004
- Author(s)
  Suzuki S, Wenyi Z, Hirai M, Hinokio Y, Suzuki C, et al.
- Journal Title
  
  Peptide 25
  
  Pages: 1801-1808
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Diabetes mellitus with mitochondrial gene mutations in Japan.2004
- Author(s)
  Suzuki S
- Journal Title
  
  Ann N Y Acad Sci 1011
  
  Pages: 185-192
- Data Source
  KAKENHI-PROJECT-16390259
[Journal Article] Promoter polymorphism of SLC11A1 (formerly NRAMP1) confers susceptibility to autoimmune type 1 diabetes mellitus in Japanese.2004
- Author(s)
  Takahashi K, Satoh J, Suzuki S, Matsuura N, et al.
- Journal Title
  
  Tissue Antigens 63
  
  Pages: 231-236
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Promoter polymorphism of SLC11A1(formerly NRAMP1) confers susceptibility to autoimmune type 1 diabetes mellitus in Japanese.2004
- Author(s)
  Takahashi K, Satoh J, Suzuki S, Matsuura N, et al.
- Journal Title
  
  Tissue Antigens 63
  
  Pages: 231-236
- Data Source
  KAKENHI-PROJECT-16390259
[Journal Article] Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2 : Hints for the design of selective NEU3 inhibitors.
- Author(s)
  Magesh S, Suzuki T, Miyagi T et al.
- Journal Title
  
  J Mol Graph Model (印刷中)
- Data Source
  KAKENHI-PROJECT-16390259

1. HINOKIO Yoshinori (10282071)

# of Collaborated Projects: 10 results

# of Collaborated Products: 14 results
2. HIRAI Masashi (80312578)

# of Collaborated Projects: 8 results

# of Collaborated Products: 11 results
3. ISHIHARA Hisamitsu (60361086)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
4. KATAGIRI Hideki (00344664)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. 豊田隆謙 (40003628)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MIYAGI Taeko (50006110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 佐藤義憲 (50241633)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SHIMIZU Fumio (10162710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MONMA Yuko (00191073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAMURA Akira (00375023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 高橋和眞 (60292215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SUZUKI Susumu 鈴木 進

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膵ラ島β細胞ミトコンドリアを標的とする遺伝子治療の開発Principal Investigator

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Elucidation of abnormality of plasma membrane microdomain in type 2 diabetes mellitusPrincipal Investigator

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The role of plasma membrane type sialidase gene Neu3 on the pathogenesis of type 2 diabetes mellitusin Japanese.Principal Investigator

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Development of a new assay method for oxidative DNA damages in diabetesPrincipal Investigator

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Role of oxidative DNA damage in the pathogenesis of diabetic complicationsPrincipal Investigator

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NIDDMにおける末梢型ベンゾジアゼピン受容体機能異常の分子生物学的検討Principal Investigator

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SUZUKI Susumu 鈴木進