NAKAJIMA Satoshi 中嶋敏

Researcher Number	00375114
Affiliation (based on the past Project Information) *help	2010: 東北大学, 加齢医学研究所, 助教 2009: 東北大, 加齢医学研究所, 助教 2007 – 2008: Tohoku University, Institute of Development, Aging and Cancer, Assistant Prof. 2004 – 2006: 東北大学, 加齢医学研究所, 助手
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals Except Principal Investigator Risk sciences of radiation/Chemicals / Biological Sciences
Keywords	Principal Investigator DNA修復 / ゲノム安定性 / プロテオーム / 遺伝子 / DNA損傷トレランス / in situ解析 Except Principal Investigator DNA修復 / 活性酸素 / 癌化 / 細胞老化 … More / PARP / DNA切断 / APエンドヌクレアーゼ / プロテオミクス / 可視化解析 / 単鎖切断 / Aging / cancer / DNA strand breaks / proteomics / visual analysis / reactive oxygen species / DNA repair / DNA damage / リアルタイム解析 / 放射線 / レーザー / 生体分子 / 癌 / 可視化 / 二重鎖切断 / 塩基損傷 / 老化 / 発癌 / DNA損傷 / ポリADPリボース / in situ解析 / PALF / ゲノム不安定性 / 細胞死 / XRCC1 / 乳がん / 癌治療 Less

Novel DNA damage responses and repair regulated by poly-ADP ribosylation and chromatin remodeling
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
蛋白質の可視化とプロテオーム解析による複製後修復の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  中嶋敏
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
ゲノム単鎖切断に関わるゲノム不安定性と細胞死
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
in situ解析法を用いたヒト細胞でのDNA損傷トレランスの研究Principal Investigator
- Principal Investigator
  
  中嶋敏
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
Live cell analysis of cellular responses to various types of DNA damage induced by reactive oxygen
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University

All 2011 2010 2009 2008 2006 2005 2004

All Journal Article Presentation

[Journal Article] The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Poll η in response to oxidative DNA damage in human cells2011
- Author(s)
  Zlatanou A, Despras E, Braz-Petta T, Boubakour-Azzouz I, Pouvelle C, Stewart GS, Nakajima S, Yasui A, Ishchenko AA, Kannouche PL
- Journal Title
  
  Mol Cell
  
  Volume: 43(4) Pages: 649-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Histone acetylation by p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors2011
- Author(s)
  Ogiwara H, Ui A, Otsuka A, Satoh H, Ymi I, Nakajima S, Yasui A, , Yokota J, and Kohno T
- Journal Title
  
  Oncogene
  
  Volume: 18 Pages: 2135-2146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] The ACF1 complex is required for DNA double-strand break repair in human cells2010
- Author(s)
  Lan L, Ui A, Nakajima S, Hatakeyama K, Hoshi M, Watanabe R, Janicki S, Ogiwara H, Kohno T, Kanno SI, and Yasui A
- Journal Title
  
  Mol Cell
  
  Volume: 40 Pages: 976-987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.2009
- Author(s)
  Ziv O, Geacintov, N.Nakajima, S, Yasui, A.Livneh, Z.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages: 11552-11557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients2009
- Author(s)
  Ziv O, Geacintov N, Nakajima S, Yasui A, and Livneh Z
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 106 Pages: 11552-11557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Human DNA polymerase iota protects cells against oxidative stress2008
- Author(s)
  Petta TB, Nakajima S, Zlatanou A, Despras E, Sarasin A, Yasui A, and Kannouche P
- Journal Title
  
  EMBO J
  
  Volume: 27 Pages: 2883-2895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell2008
- Author(s)
  Hong Z, Jiang J, Lan L, Nakajima S, Kanno S, Koseki H, and Yasui A
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 36 Pages: 2937-2947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Replication-dependent and -independent responses of RAD18 to DNA damage in human cells.2006
- Author(s)
  Nakajima S et al.
- Journal Title
  
  The journal of biological chemistry 281・45
  
  Pages: 34687-34695
- Data Source
  KAKENHI-PROJECT-17710042
[Journal Article] Replication-dependent and-independent responses of RAD18 to DNA damage in human cells.2006
- Author(s)
  Nakajima, et al
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 34687-34695
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] Replication-dependent and -independent responses of RAD18 to DNA damage in human cells.2006
- Author(s)
  Nakajima, S., 他
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 34687-34695
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] Replication-dependent and -independent responses of RAD18 to DNA damage in human cells.2006
- Author(s)
  Nakajima, S, et al.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 34687-34695
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] Accumulation of Werner protein at DNA double-strand breaks in human cells2005
- Author(s)
  Lan L., Nakajima S, Komatsu K, Nussenzweig A, Shimamoto A, Oshima J, Yasui A.
- Journal Title
  
  J. Cell Sci. 118
  
  Pages: 4153-4162
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] Powerful skin cancer protection by a CPD-photolyase transgene2005
- Author(s)
  Jans J, Schul W, Sert Y-G, Rijksen Y, Rebel H, Eker APM, Nakajima S, van Steeg H, de Gruiji FR, Yasui A, Hoejimakers JHJ, van der Horst GTJ
- Journal Title
  
  Curr. Biology 15
  
  Pages: 1-20
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] UV Light-induced DNA Damage and Tolerance for the Survival of Nucleotide Excision Repair-deficient Human Cells2004
- Author(s)
  Nakajima S.et al.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 46674-46677
- Data Source
  KAKENHI-PROJECT-16201010
[Presentation] Repair of DNA strand breaks in living human cells and implications for cancer therapy2009
- Author(s)
  Yasui A, Lan L, Nakajima S, Hatakeyama K, Zehui H, and Kanno SI
- Organizer
  40^<th> International Symposium of the Princess Takamatsu Cancer Research Fund
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] Spatio-temporal organization of DNA single-strand break repair by PARP, PARG and XRCC1 in human cell2009
- Author(s)
  Lan L, Nakajima S, Hong S, Kanno SI, and Yasui A.
- Organizer
  DNA Repair and Mutagenesis, ASM Conference
- Place of Presentation
  Whistler, BC, Canada
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] Novel AP endonuclease with 3'-5' exonuclease and single-strand break repair activities in human cell2008
- Author(s)
  Kanno SI, Sasao S, Kuzuoka H, Suzuki C, Lan L, Nakajima S, and Yasui A.
- Organizer
  6^<th> 3R Symposium
- Place of Presentation
  Awajishima Yumebutai, Japan
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] Novel AP endonuclease with exonuclease activity and DNA strand break repair in human cell2008
- Author(s)
  Kanno SI, Lan L, Nakajima S, and Yasui A
- Organizer
  10^<th> International Workshop on Radiation Damage to DNA
- Place of Presentation
  Urabandai, Fukushima, Japan
- Data Source
  KAKENHI-PROJECT-20241011

1. YASUI Akira (60191110)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. TAKAO Masashi (70216612)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KANNO Shinichirou (10400417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. TANAKA Kouzo (00304452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAJIMA Satoshi 中嶋 敏

Research Projects

Research Products

Co-Researchers

Novel DNA damage responses and repair regulated by poly-ADP ribosylation and chromatin remodeling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

蛋白質の可視化とプロテオーム解析による複製後修復の分子メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ゲノム単鎖切断に関わるゲノム不安定性と細胞死

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

in situ解析法を用いたヒト細胞でのDNA損傷トレランスの研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Live cell analysis of cellular responses to various types of DNA damage induced by reactive oxygen

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Poll η in response to oxidative DNA damage in human cells2011

Author(s)

Journal Title

Data Source

[Journal Article] Histone acetylation by p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors2011

Author(s)

Journal Title

Data Source

[Journal Article] The ACF1 complex is required for DNA double-strand break repair in human cells2010

Author(s)

Journal Title

Data Source

[Journal Article] DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.2009

Author(s)

Journal Title

Data Source

[Journal Article] DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients2009

Author(s)

Journal Title

Data Source

[Journal Article] Human DNA polymerase iota protects cells against oxidative stress2008

Author(s)

Journal Title

Data Source

[Journal Article] A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell2008

Author(s)

Journal Title

Data Source

[Journal Article] Replication-dependent and -independent responses of RAD18 to DNA damage in human cells.2006

Author(s)

Journal Title

Data Source

[Journal Article] Replication-dependent and-independent responses of RAD18 to DNA damage in human cells.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Replication-dependent and -independent responses of RAD18 to DNA damage in human cells.2006

Author(s)

Journal Title

Data Source

[Journal Article] Replication-dependent and -independent responses of RAD18 to DNA damage in human cells.2006

Author(s)

Journal Title

Description

Data Source

NAKAJIMA Satoshi 中嶋敏