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Suenaga Midori  末永 みどり

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SUENAGA Midori  末永 みどり

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Researcher Number 00389181
Other IDs
Affiliation (Current) 2025: 徳島文理大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help 2017 – 2022: 徳島文理大学, 薬学部, 講師
2015 – 2016: 徳島文理大学, 薬学部, 助教
2008 – 2013: 徳島文理大学, 薬学部, 助教
2004 – 2005: 徳島文理大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 59040:Nutrition science and health science-related
Except Principal Investigator
Laboratory medicine / Biological pharmacy
Keywords
Principal Investigator
診断 / 予防・治療 / 凝集性蛋白質 / ビタミン類 / αーシヌクレイン / TDP-43 / α-シヌクレイン / プリオンタンパク質 / アミロイドβ / 活性型ビタミンD不活化酵素 … More / 25OHビタミンD水酸化酵素 / ビタミンD水酸化酵素 / 筋萎縮性側索硬化症 / 神経変性疾患 / ビタミンD代謝酵素 / ビタミンD / 脂溶性ビタミン / プリオン病 / 多系統萎縮症 / パーキンソン病 / アルツハイマー病 … More
Except Principal Investigator
アルツハイマー病 / Alkyl gallate / EGFR / Gefitinib / p21WAF1 / GADD153 / Sulindac / EGCG / 蛋白凝集 / アミロイドベータ蛋白 / ベータアミロイド / 蛋白立体構造変化 / 蛋白2次構造変化 / ビタミンD / ベータアミロイド蛋白 / ビタミンD活性体 / ビタミンD前駆体 / アルツハイマー病進行段階 / 早期アルツハイマー病 / ビタミンD / 血液検査診断 / アミロイドβ / βアミロイド蛋白凝集 / アルツハイマー病期診断 / 早期アルツハイマー病診断 / 25(OH)VD3濃度 / 1,25(OH)2VD3濃度 / 血清ビタミンD濃度 / βアミロイド蛋白 / Apoptosis / 5-FU / PC-9 / 相乗効果 / GA153DD / sulindac / Alkyl gallete / アポトーシス / アミロイドベータ蛋白特異抗体 / 蛋白加温修飾 / アルツハイマー病患者血清 / アルツハイマー病診断 / 脳内蛋白異常凝集 / ベータシート形成 / プリオン蛋白 / ビタミンD3 / ビタミンD2 / オリゴマー形成 / ベータシート構造 / 蛋白質加温凝集 / 血清診断法 / アミロイドベータ / アミロイド蛋白凝集 / ブレーカーペプチド / 温熱変化 / 患者血清 / 立体構造変化 / 診断法 / アミロイド蛋白凝集抑制 / 血清アミロイド蛋白濃度 / 記憶障害 / ブレーカーペプタイド / 血清診断 / 加温 / アミロイド蛋白 Less
  • Research Projects

    (5 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (10 People)
  •  Development of early diagnosis, prevention, and treatment for neurodegenerative diseases by vitaminsPrincipal Investigator

    • Principal Investigator
      Suenaga Midori
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tokushima Bunri University
  •  Serum vitamin D concentration is a biomarker for early stage of Alzheimer's disease and control amyliod-beta aggregation.

    • Principal Investigator
      MATSUNAGA Yoichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Tokushima Bunri University
  •  Developments of diagnostics for Mild Cognitive Impairment by patients serum and inhibition of the disease progress with vitamin D

    • Principal Investigator
      MATSUNAGA Yoichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Tokushima Bunri University
  •  A new diagnostic approach of Alzheimer's Disease based on the conformational changes of Aβ in serum

    • Principal Investigator
      MATSUNAGA Yoichi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Tokushima Bunri University
  •  Studies on proteins involved in synergistic up-regulation of apoptosis-related genes

    • Principal Investigator
      FUJIKI Hirota
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokushima Bunri University, Faculty of Pharmaceutical Sciences, Laboratory of Biochemistry

All 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

  • [Book] Vitamin D2017

    • Author(s)
      Mstsunaga Y, Suenaga M, Takahashi H, Furuta A
    • Total Pages
      14
    • Publisher
      INTECH
    • Data Source
      KAKENHI-PROJECT-15K08631
  • [Journal Article] Role of cytochrome P450 for vitamin D metabolisms in patients with neurodegenerative disorders2022

    • Author(s)
      Kakimoto Asako、Ogura Hiromu、Suenaga Midori、Mishima Takayasu、Fujioka Shinsuke、Ouma Shinji、Matsunaga Yoichi、Tsuboi Yoshio
    • Journal Title

      Clinical Parkinsonism & Related Disorders

      Volume: 7 Pages: 100162-100162

    • DOI

      10.1016/j.prdoa.2022.100162

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11009
  • [Journal Article] Circulatory 25(OH)D and 1,25(OH)2D as differential biomarkers between multiple system atrophy and Parkinson's disease patients2021

    • Author(s)
      Ogura Hiromu、Hatip-Al-Khatib Izzettin、Suenaga Midori、Hatip Funda Bolukbasi、Mishima Takayasu、Fujioka Shinsuke、Ouma Shinji、Matsunaga Yoichi、Tsuboi Yoshio
    • Journal Title

      eNeurologicalSci

      Volume: 25 Pages: 100369-100369

    • DOI

      10.1016/j.ensci.2021.100369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K11009
  • [Journal Article] A novel diagnostic marker for progressive supranuclear palsy targeting atrophy of the subthalamic nucleus2021

    • Author(s)
      Fujioka Shinsuke、Morishita Takashi、Takano Koichi、Takahashi Nobutaka、Kurihara Kanako、Nishida Akihiro、Mishima Takayasu、Suenaga Midori、Matsunaga Yoichi、Tsuboi Yoshi
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 423 Pages: 117366-117366

    • DOI

      10.1016/j.jns.2021.117366

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K11009
  • [Journal Article] Table tennis for patients with Parkinson’s disease: A single-center, prospective pilot study2021

    • Author(s)
      Inoue Kenichi、Fujioka Shinsuke、Nagaki Koichi、Suenaga Midori、Kimura Kazuki、Yonekura Yukiko、Yamaguchi Yoshiki、Kitano Kosuke、Imamura Ritsuko、Uehara Yoshinari、Kikuchi Hitoshi、Matsunaga Yoichi、Tsuboi Yoshio
    • Journal Title

      Clinical Parkinsonism & Related Disorders

      Volume: 4 Pages: 100086-100086

    • DOI

      10.1016/j.prdoa.2020.100086

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11009
  • [Journal Article] Serine Protease Inhibitors and Activators From Dalbergia Tonkinensis Species2020

    • Author(s)
      Son N, Suenaga M, Matsunaga Y, Chinh L, Kubo M, Harada K, Cuong N, Fukuyama Y
    • Journal Title

      J Nat Med

      Volume: 74 Issue: 1 Pages: 257-263

    • DOI

      10.1007/s11418-019-01347-y

    • NAID

      40022130337

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K11009, KAKENHI-PROJECT-20K05736, KAKENHI-PROJECT-16K01921
  • [Journal Article] New phenolics, cytotoxicity and chemosystematic significance of Atriplex semibaccata2019

    • Author(s)
      Elshamy Abdelsamed I.、Mohamed Tarik A.、Suenaga Midori、Noji Masaaki、Umeyama Akemi、Efferth Thomas、Hegazy Mohamed-Elamir F.
    • Journal Title

      Phytochemistry Letters

      Volume: 34 Pages: 74-78

    • DOI

      10.1016/j.phytol.2019.09.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K11009
  • [Journal Article] Seruum vitamin D in patients with mild cognitive ipairment and Alzheimer's disease.2018

    • Author(s)
      Ouma S, Suenaga M, Hatip FF,Hatip IZ, Tsuboi S, Matsunaga Y.
    • Journal Title

      Brain and Behavior

      Volume: 8 Issue: 3 Pages: 1-12

    • DOI

      10.1002/brb3.936

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08631
  • [Journal Article] Novel neurotrophic phenylbutenoids from Indonesian ginger Bangle, Zingiber purpureum.2015

    • Author(s)
      M. Kubo, M. Gima, K. Baba, M. Nakai, K. Harada, M. Suenaga, Y. Matsunaga, E. Kato, S. Hosoda, Y. Fukuyama.
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 25 Issue: 7 Pages: 1586-1591

    • DOI

      10.1016/j.bmcl.2015.02.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08012, KAKENHI-PROJECT-15K08631, KAKENHI-PROJECT-24510293
  • [Journal Article] Monocytic elastase-mediated apolipoprotein-E degradation: Potential involvement of microglial elastase-like proteases in apolipoprotein-E proteolysis in brains with Alzheimer's disease.2015

    • Author(s)
      Suenaga M, Furuta A, Wakabayashi K, Saibara T, Matsunaga Y.
    • Journal Title

      Biochem. Bipohys. Acta.

      Volume: 1854 Issue: 8 Pages: 1010-1018

    • DOI

      10.1016/j.bbapap.2015.04.028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08631
  • [Journal Article] Vitamin D2 interacts with human PrPc(90-231) and breaks PrPc oligomerization in vitro2013

    • Author(s)
      Modori Suenaga, Yoichi Matsunaga
    • Journal Title

      PRION

      Volume: 7 Issue: 4 Pages: 1-7

    • DOI

      10.4161/pri.25739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] Vitamin D_2 interacts with human PrPc(90-231) and breaks PrPc oligomerization in vitro2013

    • Author(s)
      Suenaga M, Hiramoto Y, Matsunaga Y
    • Journal Title

      PRION

      Volume: 7 Pages: 1-7

    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] Concise synthesis of a probe molecule enabling analysis and imaging of vizantin2013

    • Author(s)
      H.Yamamoto, M. Oda, M. Nakano, K. Yabuki, M. Shibutani, T. Nakanishi, M. Suenaga, M. Inoue, H. Imagawa, M. Nagahama, Y. Matsunaga, s. Himeno, K. Setsu, J. Sakurai,M. Nishizawa et al.
    • Journal Title

      Chem. Pharm. Bull.

      Volume: 61 Pages: 452-459

    • NAID

      130003360757

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] L-tryptophan suppresses rise in blood glucose and preserves insulin secretion in Type-2Diabetes Mellitus rats2012

    • Author(s)
      T. Inubishi, N. Kamemura, M. Oda, J. Sakurai, Y. Nakaya, N. Harada, M. Suenaga, Y. Matsunaga, K. Ishidoh, N. Katunuma
    • Journal Title

      J. Nutr. Vitaminol.

      Volume: 58 Pages: 415-422

    • NAID

      130003368137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] L-Tryptophan Suppresses Rise in Blood Glucose and Preserves Insulin Secretion in Type-2 Diabetes Mellitus Rats2012

    • Author(s)
      Inobushi T, Kamemura N, Oda M, Sakurai J, Nakaya Y, Harada N, Suenaga M, Matsunaga Y, Ishidoh K, KatunumaN
    • Journal Title

      J Nutr. Sci. Vitaminol

      Volume: 58 Pages: 415-422

    • NAID

      130003368137

    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] Chemical and genetic diversity of Ligularia virgaurea collected in northern Sichuan and adjacent areas of China. Isoration of 13 new compounds2012

    • Author(s)
      Saito Y, Takashima Y, Kamada A, Suzuki Y, Suenaga M, Okamoto Y, Matsunaga Y , Hanai R, Kawahara T, Gong X, Tori M
    • Journal Title

      Tetrahedron

      Volume: 68 Pages: 10011-10029

    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] Chemical and genetic diversity of Ligularia virgaurea collected in north Shichuan and adjacent areas of China. Isolation of 13 new compounds2012

    • Author(s)
      Y. saito, Y. Takashima, A. Kamada, Y. Suzuki, M. Suenaga, Y. Okamoto, Y. Matsunaga, R. Hanai, T. Kawahara, X. Gong, M. Tori
    • Journal Title

      Tetrahedron

      Volume: 68 Pages: 10011-10029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] Environmental factors preceding A-beta40 monomer to oligomers and the function of patients with Parkinson's disease patient serum2012

    • Author(s)
      Matsunaga Y, Suenaga M
    • Journal Title

      J. Amino Acids

      Volume: 2012 Pages: 1-8

    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] Environmental factors preceding A-beta 40 monomer to oligomera and the detection of oligomers in Alzheimer's disease patient serum2012

    • Author(s)
      Y. Matsunaga, M. Suenaga
    • Journal Title

      Journal of Amino Acids

      Volume: 2012 Pages: 1-8

    • DOI

      10.1155/2012/206520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] Effects of 8-residue beta sheet breaker peptides on aged A-beta40-induced memory impairment and A-beta40 expression in rat brain and serm following intraamygdaloid injection2010

    • Author(s)
      F.Hatip, Y I.Hatip, Matsunaga, M.Suenaga, N.Sen
    • Journal Title

      Current Alzheimer's Research

      Volume: 7 Pages: 602-614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590592
  • [Journal Article] Effects of 8-residue beta sheet breaker peptides on Aged Aβ40-Induced memory impairment and Aβ40 expression in rat brain and serum following intraamygdaloid injection.2010

    • Author(s)
      Hatip F F, Hatip-Al-Khatib I, Y.Matsunaga, M.Suenaga, N.Sen
    • Journal Title

      Curr Alzheimer Res 7(7)

      Pages: 602-614

    • Data Source
      KAKENHI-PROJECT-20590592
  • [Journal Article] Effects of 8-residue beta-sheet breaker peptides on aged A-beta40 induced memory impariment and A-beta40 expression in rat brain and serum fpllowing intraamygdaloid injection2010

    • Author(s)
      Hatip FB, Hatip KA, Matsunaga Y, Suenaga M, Sen N
    • Journal Title

      Curr. Alz. Res

      Volume: 7 Pages: 606-614

    • Data Source
      KAKENHI-PROJECT-23590697
  • [Journal Article] Reversal of temperature-induced conformational changes in the Amyloid-beta peptide, Aβ40, by the β-sheet breaker peptides 16-23 and 17-24.2009

    • Author(s)
      Hatip B.F, M.Suenaga, T.Yamada, Y.Matsunaga
    • Journal Title

      Br J Pharmacol 158

      Pages: 1165-1172

    • Data Source
      KAKENHI-PROJECT-20590592
  • [Journal Article] Reversal of temperature-induced conformational changes in the amyloid-beta peptides, A-beta40, by the beta-sheet breaker peptides 16-23 and 17-242009

    • Author(s)
      Funda Bolukbasi Hatip, Midori Suenaga, Tatsuo Yamada, Yoichi Matsunaga
    • Journal Title

      British Journal of Pharmacology 158

      Pages: 1165-1172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590592
  • [Journal Article] Reversal of temperature-induced conformational changes in the amyloid-beta peptide, Aβ40, by the β-sheet breaker peptides 16-23 and 17-24.

    • Author(s)
      F.Hatip, M.Suenaga, T.Yamada, Y.Matsunaga
    • Data Source
      KAKENHI-PROJECT-20590592
  • [Presentation] パーキンソン病患者に対する卓球リハビリテーション療法の有効性および安全性の検討2021

    • Author(s)
      井上 賢一、藤岡 伸助、長城 晃一、末永 みどり、木村 一喜、米倉 有希子、山口 良樹、北野 晃祐、今村 律子、上原 吉就、菊池 仁志、松永 洋一、坪井 義夫
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K11009
  • [Presentation] ビタミンD2によるアミロイドベータのベータシート構造形成誘導に関与するアミノ酸残基の検索2016

    • Author(s)
      末永みどり、松永洋一
    • Organizer
      第  日本薬学会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-15K08631
  • [Presentation] ビタミンD2によるアミロイドベータのベータシート構造形成誘導に関与するアミノ酸残基の検索2015

    • Author(s)
      末永みどり、松永洋一
    • Organizer
      第88回日本生化学会
    • Place of Presentation
      神戸市
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K08631
  • [Presentation] ビタミンDのアミロイドβおよび正常プリオン蛋白との親和性2013

    • Author(s)
      末永みどり, 高村佳香, 平本雄介, 藤澤恵美, 高橋宏暢, 松永洋一
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜市
    • Year and Date
      2013-09-11
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Presentation] ビタミンDのアミロイドベータおよびプリオン蛋白への親和性2013

    • Author(s)
      末永みどり、松永洋一
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Presentation] ヒト単球由来ApoE分解酵素の探索2012

    • Author(s)
      末永みどり, 西原利治, 松永洋一
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-12-16
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Presentation] 高濃度Vitamine D2によるベータアミロイド凝の集促進2011

    • Author(s)
      末永みどり、松永洋一、合馬信二、山田達夫
    • Organizer
      日本老年病学会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-20590592
  • [Presentation] 高濃度Vitamine D2によるbeta-amyloidの凝集促進2011

    • Author(s)
      末永みどり
    • Organizer
      第21回日本老年病学会、九州支部会
    • Place of Presentation
      福岡市
    • Year and Date
      2011-03-05
    • Data Source
      KAKENHI-PROJECT-20590592
  • [Presentation] Reversal of temperature-induced conformational changes in A-beta40 by beta-breaker peptides 16-23 and 17-24.2010

    • Author(s)
      M.Suenaga, T.Yamada, Y.Matsunaga
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-20590592
  • [Presentation] β-sheet breaker peptides 16-23及び17-24による温度誘導性Aβ40構造変化の抑制2009

    • Author(s)
      末永みどり、松永洋一
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸市
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-20590592
  • [Presentation] アルツハイマー病及びメタボリツク症候群に関与するApoE分解酵素の検索2008

    • Author(s)
      末永みどり
    • Organizer
      第81回日本生化学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-20590592
  • [Presentation] ヒト単球由来ApoE分解酵素の探索

    • Author(s)
      末永みどり、西原利治、松永洋一
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-23590697
  • [Presentation] アミロイドベータ凝集に対するビタミンD2の効果

    • Author(s)
      末永みどり、石川隼人、高村佳香、会馬慎二、山田達夫、松永洋一
    • Organizer
      日本生化学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590697
  • 1.  MATSUNAGA Yoichi (80239053)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 33 results
  • 2.  TSUBOI Yoshio (90291822)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 3.  UEHARA Yoshinari (70373149)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  YAMADA Tatsuo (50142211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 5.  FUJIKI Hirota (60124426)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KUZUHARA Takashi (00260513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKAHASHI Hironobu (90289314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  山中 浩泰 (30202386)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  古田 晶子 (50229118)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  久保 美和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

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