YAMASITA Kennitirou 山下健一郎

Researcher Number	00399940
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2019: 北海道大学, 医学研究院, 特任教授 2016: 北海道大学, 医学研究科, 特任教授 2013 – 2015: 北海道大学, 医学(系)研究科(研究院), 特任教授 2012: 北海道大学, 医学(系)研究科(研究院), 特任准教授 2010 – 2012: 北海道大学, 大学院・医学研究科, 特任准教授 … More 2007 – 2009: 北海道大学, 大学院・医学研究科, 特任助教 2006: 北海道大学, 大学病院, 医員 2006: 北海道大学大学病院, 医員 2005 – 2006: 北海道大学, 病院・医員 Less
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator General surgery / Digestive surgery
Keywords	Principal Investigator 細胞治療 / 移植免疫 / 免疫寛容 / 移植外科学 / 移植・再生医療 / 免疫抑制性細胞 / 分子標的 / 免疫抑制性 / CD40 / NF-κB / 分子標的治療 / 膵ラ氏島移植 … More Except Principal Investigator … More NF-κB / 肝移植 / 臓器保存 / 移植・再生医療 / 細胞移植 / 肝細胞移植 / 免疫寛容 / 膵島移植 / 免疫抑制細胞 / 慢性拒絶反応 / 血管移植 / 皮膚移植モデル / NSGマウス / HLA抗体 / 移植 / 抗HLA抗体 / ヒト化マウス / Adeno virus / NF-kB / reperfusion / Ischemia / Immunosuppression / Costimulatory signals / Gene therapy / Small bowel transplantation / CD40Ig / CTLA4Ig / ラット / 虚血再灌流障害 / 小腸 / マウス / 拒絶反応 / DHMEQ / T細胞 / アデノウイルス / 虚血再灌流傷害 / 免疫抑制 / 副刺激 / 遺伝子治療 / 小腸移植 / NFκB / AKT / GSK-3β / マクロファージ / DTCM-G / 腸管免疫 / 炎症性腸疾患 / 臓器移植 / 心臓死ドナー / 移植片機能不全 / 灌流保存 / 冷保存再灌流障害 / 臓器保存液 / 移植外科 / NFkB阻害剤 / 動脈硬化 / ステント / 薬学 / 構造・機能材料 / 循環器・高血圧 / 外科 / 医療・福祉 / 大腸炎モデル / 大腸炎 / 炎症性腸炎 / 肺障害 / サイトカイン / 小腸虚血再灌流障害 / 肝 / 細胞骨格 / 嫌気代謝 / 冷保存再灌流 / 冷保存 / 重水 Less

Development of a new strategy for long-term graft acceptance after pancreatic islet transplantation
- Principal Investigator
  
  Watanabe Masaaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
The role of anti-donor HLA antibodies and the its treatment in organ transplantation
- Principal Investigator
  
  Goto Ryoichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
体外誘導免疫制御性リンパ球を用いた細胞治療による免疫寛容誘導に関する研究Principal Investigator
- Principal Investigator
  
  山下健一郎
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Basic studies for induction of tolerance by a cell-therapyPrincipal Investigator
- Principal Investigator
  
  YAMASHITA KENICHIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Development of a new strategy for pancreatic islet transplantation by molecular targeting agentsPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Kenichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Development of a novel organ preservation solution for the use of liver transplantation
- Principal Investigator
  
  TODO Satoru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
New Treatment Strategies for Inflammatory Bowel Disease using a novel NF-κB inhibitior (DHMEQ)
- Principal Investigator
  
  SUZUKI Tomomi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hokkaido University
転写因子NFkBをターゲットとした新しい薬剤流出ステントの開発
- Principal Investigator
  
  藤堂省
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
The novel NF-kB inhibitor, dehydroxymethylepoxyquinomicin, prevents local intestinal ischemia/reperfusion injury in rats
- Principal Investigator
  
  SUZUKI Tomomi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
水素の動きを制御することにより阻血再灌流障害のシグナルを制御する試み
- Principal Investigator
  
  FUKAI Moto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Hokkaido University
Development of a gene therapy based new strategy in small bowel transplantation
- Principal Investigator
  
  FURUKAWA Hiroyuki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Hokkaido University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] A pilot study of operational tolerance with a regulatory T cell-based cell therapy in living donor liver transplantation.2016
- Author(s)
  ①Todo S, Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Bashuda H, Habu S, Demetris AJ, Okumura K
- Journal Title
  
  Hepatology
  
  Volume: 00 Issue: 2 Pages: 00-00
- DOI
  10.1002/hep.28459
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461964, KAKENHI-PROJECT-26253068, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-16K08683, KAKENHI-PROJECT-26670572, KAKENHI-PROJECT-16H05398
[Journal Article] The efficacy of DHMEQ, a NF- κ B inhibitor , in islet transplantation : II. Induction DHMEQ treatment ameliorates subsequent allo-immune responses, and permits a long-term islet allograft acceptance2013
- Author(s)
  Watanabe M, Y amashita K, Kamachi H, Kuraya D, Koshizuka Y, Shibasaki S, Asahi Y, Ono H, Emoto S, Ogura M, Y oshida T, Ozaki M, Umezawa K, Matsushita M, T odo S
- Journal Title
  
  Transplantation
  
  Volume: 96(5) Issue: 5 Pages: 454-62
- DOI
  10.1097/tp.0b013e31829b077f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390309
[Journal Article] The efficacy of DHMEQ, a NF- κ B inhibitor , in islet transplantation : I. HMGB1 suppression by DHMEQ prevents early islet graft damage2013
- Author(s)
  Kuraya D, Watanabe M, Koshizuka Y, Ogura M, Y oshida T, Asahi Y, Kamachi H, Nakamura T, Harashima H, Ozaki M, Umezawa K, Matsushita M, Y amashita K, T odo S
- Journal Title
  
  Transplantation
  
  Volume: 96(5) Issue: 5 Pages: 445-53
- DOI
  10.1097/tp.0b013e31829b0744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390309
[Journal Article] Immunosuppressive effects of DTCM-G, a novel inhibitor of the mTOR downstream signaling pathway.2013
- Author(s)
  Shibasaki S
- Journal Title
  
  Transplantation
  
  Volume: 95 Issue: 4 Pages: 542-550
- DOI
  10.1097/tp.0b013e31827b3d90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J06373, KAKENHI-PROJECT-22249048, KAKENHI-PROJECT-25670548
[Journal Article] ASKP1240, a fully human anti-CD40 monoclonal antibody , prolongs pancreatic islet allograft survival in nonhuman primates2013
- Author(s)
  Watanabe M, Y amashita K, Suzuki T, Kamachi H, Kuraya D, Koshizuka Y, Ogura M, Y oshida T, Aoyagi T, Fukumori D, Shimamura T, Okimura K, Maeta K, Miura T, Sakai F, T odo S
- Journal Title
  
  Am J Transplant
  
  Volume: 13(8) Issue: 8 Pages: 1976-88
- DOI
  10.1111/ajt.12330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390309
[Journal Article] Long-Term Hepatic Allograft Acceptance Based on CD40 Blockade by ASKP1240 in Nonhuman Primates2012
- Author(s)
  Oura T, Yamashita K, Todo S. et al
- Journal Title
  
  Am JTransplant
  
  Volume: 12(7) Pages: 1740-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249048
[Journal Article] Immunosuppressive Effects ofDTCM-G, a Novel Inhibitor of the mTOR Downstream Signaling Pathway2012
- Author(s)
  Shibasaki S, Yamashita K, Todo S. et al
- Journal Title
  
  Transplantation
  
  Volume: 95(4) Pages: 542-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249048
[Journal Article] Immunomodulatory effect of nuclear factor-κB inhibition bydehydroxymethyl -epoxyquinomicin in combination with donor-specific blood transfusion2012
- Author(s)
  Goto R, Yamashita K, Todo S. et al
- Journal Title
  
  Transplantation
  
  Volume: 93(8) Pages: 777-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249048
[Journal Article] Induction of insulin-dependent diabetes mellitus by total pancreatectomy for pancreatic islet transplantation in cynomolgus monkeys2012
- Author(s)
  Yoshida T, Suzuki T, Watanabe M, Yamashita K, Koshizuka Y, Kuraya D, Ogura H, Kamachi H, Matsushita M, Todo S
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: 19(6) Issue: 6 Pages: 661-6
- DOI
  10.1007/s00534-011-0485-3
- NAID
  10031126982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390309
[Journal Article] A novel NF-kB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice2012
- Author(s)
  Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 6 Pages: 215-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591474
[Journal Article] Dendritic Cells Conditioned With NK026680 Prolong Cardiac Allograft Survival in Mice2012
- Author(s)
  Shibasaki S, Yamashita K, Todo S.et al
- Journal Title
  
  Transplantation
  
  Volume: 93(12) Pages: 1229-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249048
[Journal Article] Anovel NF-κB inhibitor,dehydroxymethyl -epoxyquinomicin, ameliorates inflammatory colonic injury in mice2011
- Author(s)
  Funakoshi T, Yamashita K, Todo S
- Journal Title
  
  J Crohns Colitis
  
  Volume: 6(2) Pages: 215-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249048
[Journal Article] 肝移植Crossfire : 免疫抑制剤と肝移植術後、免疫抑制剤フリーは可能か」(解説/特集)2008
- Author(s)
  山下健一郎
- Journal Title
  
  肝・胆・膵 56
  
  Pages: 613-624
- Data Source
  KAKENHI-PROJECT-20659196
[Journal Article] The novel NF-kB inhibitor, dehydroxymethylepoxyquinomicin, prevents local and organ injury following intestinal ischemia/reperfusion in rats2008
- Author(s)
  Suzuki T, Yamashita K, Jomen W, Ueki S, Aoyagi T, Fukai M, Furukawa H, Umezawa K, Ozaki M, and Todo S.
- Journal Title
  
  J Surg Res Sep : 149(1)
  
  Pages: 69-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591470
[Presentation] Operational tolerance with a donor antigen specific immunomodulatory cell therapy in living donor liver transplantation2019
- Author(s)
  Masaaki Watanabe, Ryoichi Goto, Kenichiro Yamashita, Satoru Todo, Tsuyoshi Shimamura, and Akinobu Taketomi
- Organizer
  Asian-Pacific Hepato-Pancreato-Biliary Association
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10501
[Presentation] 膵島移植の成績改善に向けて　我々のこれまでの取り組みとこれからの展開2019
- Author(s)
  渡辺正明腰塚靖之渋谷一陽蔵谷大輔小倉正臣吉田雅旭火華後藤了一財津雅昭川村典生嶋村剛山下健一郎藤堂省武冨紹信
- Organizer
  日本外科学会定期学術総会
- Data Source
  KAKENHI-PROJECT-17K10501
[Presentation] The immune monitoring for operationally tolerant recipients following a regulatory T cell-based cell therapy2018
- Author(s)
  Ryoichi Goto, Masaaki Zaitsu, Akihisa Nagatsu, Shin Emoto, Yasutomo Fukasaku, Yoshikazu Ganchiku, Masaaki Watanabe, Tetsu Oura, Minoru Ota, Tomomi Suzuki, Tsuyoshi Shimamura, Satoru Todo, Kenichiro Yamashita
- Organizer
  The Transplant Society 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10416
[Presentation] Tolerance induction in clinical liver transplantation2017
- Author(s)
  Yamashita K
- Organizer
  Advancing Transplantation II
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2017-03-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] Immunotherapie apres TH, utilisant des Treg specifiques du donneur2017
- Author(s)
  Yamashita K
- Organizer
  Club de la Transplantation 201７
- Place of Presentation
  Lille, France
- Year and Date
  2017-02-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] The role of regulatory T cells in liver transplantation tolerance2016
- Author(s)
  Yamashita K
- Organizer
  Transplantation Science Symposium Asian Regional Meeting 2016
- Place of Presentation
  KFCホール（東京都墨田区）
- Year and Date
  2016-04-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 生体肝移植における制御性T細胞を用いた免疫寛容誘導法の臨床試験2016
- Author(s)
  山下健一郎、財津雅昭、後藤了一、長津明久、鈴木友己、嶋村　剛、神山俊哉、場集田　寿、奥村　康、藤堂　省
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] A clinical trial of cell therapy-based tolerance induction in living donor liver transplantation: Long-term follow-up results2016
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Bashuda H, Okumura K, Todo S
- Organizer
  26th International Congress of The Transplantation Society
- Place of Presentation
  Hong Kong, China
- Year and Date
  2016-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 肝移植における免疫寛容誘導2016
- Author(s)
  山下健一郎
- Organizer
  第34回日本肝移植研究会
- Place of Presentation
  大雪クリスタルホール（北海道旭川市）
- Year and Date
  2016-07-07
- Invited
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] The role of regulatory T cells in liver transplantation tolerance2016
- Author(s)
  Yamashita K
- Organizer
  Samsung Medical Center Organ Transplantation Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-03-25
- Invited
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 肝移植における免疫寛容誘導の試み2016
- Author(s)
  山下健一郎
- Organizer
  第25回日本組織適合性学会総会
- Place of Presentation
  北海道大学学術交流会館（北海道札幌市）
- Year and Date
  2016-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 臓器移植における細胞治療を用いた免疫寛容誘導2016
- Author(s)
  山下健一郎
- Organizer
  第35回日本心臓移植研究会
- Place of Presentation
  ホテルさっぽろ芸文館（北海道札幌市）
- Year and Date
  2016-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] A clinical trial of cell therapy-based tolerance induction in living donor liver transplantation: An update2015
- Author(s)
  Yamashita K, Todo S
- Organizer
  2nd International Workshop for Clinical Tolerance
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2015-10-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] A Clinical trial of cell therapy-based tolerance induction in living donor liver transplantation: An update2015
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Demetris AJ, Bashuda H, Okumura K, Todo S
- Organizer
  17th Congress of the European Society for Organ Transplantation
- Place of Presentation
  Brussels, Belgium
- Year and Date
  2015-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 細胞治療による免疫寛容誘導2015
- Author(s)
  山下健一郎
- Organizer
  第1回肝移植周術期管理マネージメントフォーラム
- Place of Presentation
  メルパルク京都（京都府京都市）
- Year and Date
  2015-01-24
- Invited
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 成人肝移植症例のマネージメントの課題 -特に免疫抑制療法に関連する諸問題について-2015
- Author(s)
  山下健一郎
- Organizer
  第33回日本肝移植研究会
- Place of Presentation
  ホテルオークラ神戸（兵庫県神戸市）
- Year and Date
  2015-05-28
- Invited
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 肝移植における免疫寛容誘導の実際2015
- Author(s)
  山下健一郎
- Organizer
  第11回移植医療教育セミナー
- Place of Presentation
  ジョンソン・エンド・ジョンソン本社（東京都千代田区）
- Year and Date
  2015-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 肝移植における免疫抑制療法2014
- Author(s)
  山下健一郎
- Organizer
  第4回北海道臓器移植者のつどい
- Place of Presentation
  札幌サンプラザ（北海道札幌市）
- Year and Date
  2014-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 抗CD80抗体、抗CD86抗体下共培養により誘導される免疫抑制性細胞の同定2014
- Author(s)
  長津明久、山下健一郎、江本　慎、旭　火華、財津雅昭、小倉正臣、小野　仁、常俊雄介、後藤了一、五十嵐瑠美、場集田　寿、奥村　康、武冨紹信、藤堂　省
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-04-03
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] A clinical trial of cell-therapy based on donor antigen-pulsed regulatory T cells for induction of operational tolerance in living donor liver transplantation2014
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Demetris AJ, Bashuda H, Okumura K, Todo S
- Organizer
  The 3rd International Conference on Immune Tolerance 2014
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2014-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] Successful Withdrawal of Immunosuppression by a Cell Therapy Using Donor Ag-pulsed Tregs in Living Donor Liver Transplantation: An Update on Clinical Trial2014
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Bashuda H, Okumura K, Todo S
- Organizer
  2014 Joint International Congress of ILTS, ELITA & LICAGE
- Place of Presentation
  London, UK
- Year and Date
  2014-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] Inducion of Operational Tolerance by a Cell Therapy using Donor Ag-pulsed Tregs in Living Donor Liver Transplantation2014
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Demetris AJ, Bashuda H, Okumura K, Todo S
- Organizer
  World Transplant Congress 2014
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2014-07-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 生体肝移植における門脈圧および門脈血流の術後早期予後に及ぼす影響2013
- Author(s)
  青柳武史、山下健一郎、藤堂省、他
- Organizer
  第113回日本外科学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22249048
[Presentation] Roles of CD40-CD40L costimulatory pathway in pancreatic islet transplantation2013
- Author(s)
  Koshizuka Y , Watanabe M, Suzuki T , Kamachi H, Ogura M, Yoshida T , Kuraya D, Fukumori D, Shimamura T , Okimura K, Maeta K, Miura T , Sakai F , T'odo S, Yamashita K
- Organizer
  3rd ESOT Basic Science Meeting & 13th TTS Basic Science Symposium
- Place of Presentation
  Paris, France
- Year and Date
  2013-11-08
- Data Source
  KAKENHI-PROJECT-23390309
[Presentation] EX-VIVO GENERATION OF HUMAN REGULATORY T CELLS BY CD80/CD86 COSTIMULATION BLOCKADE2013
- Author(s)
  Akihisa Nagatsu, Kenichiro Yamashita, Masaaki Zaitsu, Shin Emoto, Yoh Asahi, Hitoshi Ono, Ryoichi Goto, Hisashi Bashuda, Akinobu Taketomi, Ko Okumura, Satoru Todo
- Organizer
  16th Congress of the European Society for Organ Transplantation
- Place of Presentation
  Austria Centre Vienna (ACV), Vienna, Austria
- Data Source
  KAKENHI-PROJECT-25670548
[Presentation] Improvement of normoglycemic rate by Proliferater-activated receptor-gamma agonist, pioglitazone, in canine islet autotransplantation2013
- Author(s)
  Asahi Y , Yamashita K, Watanabe M, Ogura M, Ono H, Emoto S, Nagatsu A, Yoshida T , Koshizuka Y , Taketomi A, Todo S
- Organizer
  16th Congress of the European Society for Organ Transplantation
- Place of Presentation
  Vienna, Austria
- Year and Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-23390309
[Presentation] 膵島移植における分子標的治療薬を用いた免疫療法 -膵島移植成績の向上に向けて-2012
- Author(s)
  山下健一郎
- Organizer
  第39回日本膵・膵島移植研究会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-23390309
[Presentation] A Novel Anti-Inflammatory Agent, 3-[(dodecylthiocarbonyl)-methyl]-glutar imide, Ameliorates Murine Models of Inflammatory Bowel Disease2011
- Author(s)
  Ichikawa N, Yamashita K, Funakoshi T, Shibasaki S, Ichihara S, Kobayashi N, Koshizuka Y, Zaitsu M, Fukai M, Suzuki T, Ozaki M, Umezawa K, Todo S
- Organizer
  Digestive Disease Week
- Place of Presentation
  McCormick Place, Chicago, US
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] A novel NF-□B i nhi bit or , DHMEQ, ameliorates inflammatory colonic injuries in mice.2010
- Author(s)
  Funakoshi T, Yamashita K, Ichikawa N,Kobayashi N, Fukai M, Suzuki T, Goto R, Oura T, Katsurada T, Ozaki M, Umezawa K, Todo S.
- Organizer
  Digestive Disease Week 2010
- Place of Presentation
  Morial ConventionCenter, New Orleans, US
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] A Novel Anti-Inflammatory Agent,3-[(dodecylthiocarbonyl)-methyl]-glutar imide, Ameliorates Murine Models of Inflammatory Bowel Disease2010
- Author(s)
  Ichikawa N, Yamashita K, Funakoshi T, Ichihara S, Kobayashi N, Koshizuka Y, Zaitsu M, Ogura M, Yoshida T, Tsunetoshi Y, Fukai M, Suzuki T, Ozaki M, Umezawa K, Todo S
- Organizer
  The 25th ISUCRS Biennial Congress
- Place of Presentation
  Palazzo della Cultura e dei Congressi, Bologna, Italy
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] A Novel Anti-Inflammatory Agent, DTCM-Glutarimide2010
- Author(s)
  Ichikawa N, Yamashita K, Funakoshi T, Shibasaki S, Ichihara S, Fukai M, Suzuki T, Ozaki M, Umezawa K, Todo S
- Organizer
  AttenuatesExperimental Colitis in Mice Digestive Disease Week
- Place of Presentation
  Morial Convention Center, New Orleans, US
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] 新規NF-κB阻害剤DHMEQの大腸炎モデルにおける炎症抑制作用2010
- Author(s)
  舩越徹、市川伸樹、山下健一郎、深井原、鈴木友己、桂田武彦、後藤了一、大浦哲、小林希、尾崎倫孝、梅澤一夫、藤堂省
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋,名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] 炎症性腸疾患モデルに対するDTCM-glutarimideの効果に関する検討2010
- Author(s)
  市川伸樹、山下健一郎、船越徹、柴崎晋、深井原、尾崎倫孝、梅澤一夫、藤堂省
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] The therapeutic effect of a novelNF-□B inhibitor, DHMEQ, on experimentalcolitis in mice.2010
- Author(s)
  Funakoshi T, Yamashita K, Ichikawa N, Kobayashi N, Fukai M, Suzuki T, Goto R, Oura T, Katsurada T, Ozaki M, Umezawa K, Todo S.
- Organizer
  The 24th ISUCRS Biennial Congress
- Place of Presentation
  COEX, Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] 新規NF-κB阻害剤DHMEQのDSS誘発大腸炎抑制効果2009
- Author(s)
  舩越徹、山下健一郎、深井原、鈴木友巳、木本好美、長山紘明、後藤了一、大浦哲、梅澤一夫、尾崎倫孝、藤堂省
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡、福岡国際会議場
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] Immunomodulation induced by a novel immunosuppressant, NK026680 plus donor specific transfusion permits a long-term cardiac allograft survival in mice
- Author(s)
  Emoto S, Goto R, Shibasaki S, Nagatsu A, Ono H, Igarashi R, Aoyagi T, Fukai M, Shimamura T, Saiga K, Taketomi A, Todo S, Yamashita K
- Organizer
  World Transplant Congress 2014
- Place of Presentation
  Moscone West Convention Center, San Francisco, CA, USA
- Year and Date
  2014-07-26 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25670548
[Presentation] Successful Withdrawal of Immunosuppression by a Cell Therapy Using Donor Ag-pulsed Tregs in Living Donor Liver Transplantation
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Bashuda H, Okumura K, Todo S
- Organizer
  2014 Joint International Congress of ILTS, ELITA & LICAGE
- Place of Presentation
  Queen Elizabeth II Conference Center, London, UK
- Year and Date
  2014-06-04 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25670548
[Presentation] IMPROVEMENT OF NORMOGLYCEMIC RATE BY PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA AGONIST, PIOGLITAZONOE, IN CANINE ISLET
- Author(s)
  Asahi Y, Yamashita K,Watanabe M, Ogura M, Ono H, Emoto S, Nagatsu A,　Yoshida T,Koshizuka Y,Taketomi A, Todo S.
- Organizer
  16th Congress of the European Society for Organ Transplantation
- Place of Presentation
  Austria Center Vienna (Vienna, Austria)
- Data Source
  KAKENHI-PROJECT-23390309
[Presentation] NK026680とdonor specific transfusion併用による免疫修飾効果
- Author(s)
  江本　慎、後藤了一、柴崎　晋、長津明久、小野　仁、青柳武史、深井　原、武冨紹信、嶋村　剛、藤堂　省、山下健一郎
- Organizer
  第50回日本移植学会総会
- Place of Presentation
  京王プラザホテル（東京都）
- Year and Date
  2014-09-10 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25670548
[Presentation] 炎症性腸疾患モデルにおける新規化合物DTCM-Gの腸炎抑制効果に関する検討
- Author(s)
  市川伸樹、山下健一郎、舩越徹、吉田雅、小林希、腰塚靖之、財津雅昭、柴崎晋、常俊雄介、小倉正臣、深井原、市原真、尾崎倫孝、梅澤一夫、藤堂省
- Organizer
  第111回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22591474
[Presentation] 抗CD80抗体、抗CD86抗体下共培養により誘導される免疫抑制性細胞の同定
- Author(s)
  長津明久、山下健一郎、江本　慎、旭　火華、財津雅昭、小倉正臣、小野　仁、常俊雄介、後藤了一、五十嵐瑠美、場集田　寿、奥村　康、武冨紹信、藤堂省
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-25670548
[Presentation] Inducion of Operational Tolerance by a Cell Therapy using Donor Ag-pulsed Tregs in Living Donor Liver Transplantation
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Demetris AJ, Bashuda H, Okumura K, Todo S
- Organizer
  World Transplant Congress 2014
- Place of Presentation
  Moscone West Convention Center, San Francisco, CA, USA
- Year and Date
  2014-07-26 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25670548
[Presentation] Prevention of early graft loss by Proliferator-activated receptor-gamma agonist, pioglitazonoe, in canine islet autotransplantation
- Author(s)
  Asahi Y, Yamashita K,Watanabe M,Ogura M,Ono H,Handly DE, Emoto S, Nagatsu A, Yoshida T,Koshizuka Y, Kamachi H, Taketomi A, Todo S.
- Organizer
  American Transplant Congress
- Place of Presentation
  Washington State Convention & Trade Center (Seattle, U.S.A.)
- Data Source
  KAKENHI-PROJECT-23390309

1. OZAKI Michitaka (80256510)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
2. TODO Satoru (60136463)

# of Collaborated Projects: 6 results

# of Collaborated Products: 19 results
3. FURUKAWA Hiroyuki (70292026)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
4. SHIMAMURA Tsuyoshi (00333617)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
5. GOTO Ryoichi (10645287)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
6. SUZUKI Tomomi (70374238)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
7. FUKAI Moto (60374344)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MATSUSHITA Michiaki (20250425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. SUGAWARA Mitsuru (60332467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TANIGUCHI Masahiko (30374333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAMACHI Hirofumi (60374237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. UMEZAWA Kazuo (70114402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AOYAGI Takeshi (90374347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. UEDA Toshimitsu (00160185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Watanabe Masaaki (40789848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 熊谷純 (20303662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 奥村康 (50009700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
18. Fukasaku Yasutomo

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 場集田寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

YAMASITA Kennitirou 山下 健一郎

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体外誘導免疫制御性リンパ球を用いた細胞治療による免疫寛容誘導に関する研究Principal Investigator

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Basic studies for induction of tolerance by a cell-therapyPrincipal Investigator

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Development of a new strategy for pancreatic islet transplantation by molecular targeting agentsPrincipal Investigator

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[Journal Article] A pilot study of operational tolerance with a regulatory T cell-based cell therapy in living donor liver transplantation.2016

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[Journal Article] The efficacy of DHMEQ, a NF- κ B inhibitor , in islet transplantation : II. Induction DHMEQ treatment ameliorates subsequent allo-immune responses, and permits a long-term islet allograft acceptance2013

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[Journal Article] The efficacy of DHMEQ, a NF- κ B inhibitor , in islet transplantation : I. HMGB1 suppression by DHMEQ prevents early islet graft damage2013

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[Journal Article] Immunosuppressive effects of DTCM-G, a novel inhibitor of the mTOR downstream signaling pathway.2013

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YAMASITA Kennitirou 山下健一郎

[Presentation] 膵島移植の成績改善に向けて　我々のこれまでの取り組みとこれからの展開2019