MASHIMA RYUICHI 真嶋隆一

… Alternative Names

MASHIMA Ryuichi 真嶋隆一

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Researcher Number	00401365
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, 臨床検査部, 上級専門職
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人国立成育医療研究センター, 臨床検査部, 上級専門職 2019 – 2023: 国立研究開発法人国立成育医療研究センター, 臨床検査部, 上級専門職 2016 – 2018: 国立研究開発法人国立成育医療研究センター, 臨床検査部, 専門職 2015: 東京大学, 医科学研究所, 助教 2013: 慶應義塾大学, 医学部, 特任講師 … More 2012: 秋田大学, 医学(系)研究科(研究院), 助教 2008 – 2011: The University of Tokyo, 医科学研究所, 助教 2007: Tokyo Medical and Dental University, 難治疾患研究所, 助教 2005 – 2006: 東京医科歯科大学, 難治疾患研究所, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 52010:General internal medicine-related / Laboratory medicine / Respiratory organ internal medicine / Cell biology Except Principal Investigator Cell biology / Biological Sciences / Biological Sciences
Keywords	Principal Investigator バイオマーカー / 酵素活性 / 先天代謝異常症 / ライソゾーム病 / LC-MS / ムコ多糖症 / LC-MS/MS / チロシンキナーゼ / 治療モデル / イズロン酸2-スルファターゼ … More / グルコサミノグリカン / 疾患マウスモデル / 分析バリデーション / 精度管理 / 臨床検査法 / 質量分析法 / 長鎖塩基 / スフィンゴ脂質 / 網羅的手法 / 臨床検査 / グリコサミノグリカン / ID2S / 新生児スクリーニング / ムコ多糖症II型 / アダプタータンパク質 / 閉塞性肺疾患 / 疾患モデルマウス / アダプター分子 / 喘息 / チロシンリン酸化 / リン酸化 / シグナル伝達 / 細胞間情報伝達 / 細胞内 … More Except Principal Investigator 細胞・組織 / シグナル伝達 / アダプター / 蛋白質 / Protein phosphorylation / Adaptor / Organ ＆ Cells / Protein / Signal Transduction / リン酸化 / 組織・細胞 / Wnt5a-Rorシグナル / 頂底極性シグナル / 繊毛関連症候群 / 癌の浸潤転移 / 上皮間葉転換 / エピジェネティック制御 / 癌の浸潤 / 繊毛関連症候群・炎症 / 上皮管腔組織の破綻 / 線毛シグナル / 組織炎症 / 上皮管腔組織形成 / 癌の浸潤・進展 / アダプター分子 / 非古典的Wntシグナル / 繊毛シグナル / 平面細胞極性シグナル / 上皮管腔組織破綻 / 細胞内情報伝達 / タンパク質チロシンキナーゼ / シグナル会達 / 癌 Less

ライソゾーム酸性リパーゼ欠損症疾患マウスモデルの病態解析と治療法の開発Principal Investigator
- Principal Investigator
  
  真嶋隆一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Center for Child Health and Development
病態モデルマウスを利用したムコ多糖症発症メカニズムの解明と治療法の開発Principal Investigator
- Principal Investigator
  
  真嶋隆一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Center for Child Health and Development
Development of clinical assay for LSDs using LC-MS/MSPrincipal Investigator
- Principal Investigator
  
  Ryuichi Mashima
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  National Center for Child Health and Development
Development of screening and diagnostic assay for mucopolysaccharidosis type IIPrincipal Investigator
- Principal Investigator
  
  Mashima Ryuichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  National Center for Child Health and Development
Dysfunction of planar cell polarity signaling and its relationship with ciliopathies and cancer invasion and metastasis
- Principal Investigator
  
  MINAMI YASUHIRO
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
The role of Dok adaptors in pulmonary disordersPrincipal Investigator
- Principal Investigator
  
  MASHIMA Ryuichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Keio University
  Akita University
  The University of Tokyo
Molecular signaling in neuromuscular synaptogenesis, hematopoiesis, and related disorders
- Principal Investigator
  
  YAMANASHI Yuji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
Role of receptor tyrosine kinases in hematopoietic cellsPrincipal Investigator
- Principal Investigator
  
  MASHIMA Ryuichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
  Tokyo Medical and Dental University
Protein kinase signaling and malignant cell proliferation
- Principal Investigator
  
  YAMANASHI Yuji
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Tokyo Medical and Dental University
Dok-mediated regulation of cellular functions
- Principal Investigator
  
  YAMANASHI Yuji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Medical and Dental University

[Journal Article] RNA-Based Therapeutic Technology.2023
- Author(s)
  Mashima R, Takada S, Miyamoto Y.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 24(20) Issue: 20 Pages: 15230-15230
- DOI
  10.3390/ijms242015230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07927, KAKENHI-PROJECT-23K28470
[Journal Article] A novel mucopolysaccharidosis type II mouse model with an iduronate-2-sulfatase-P88L mutation2023
- Author(s)
  Ryuichi Mashima, Mari Ohira, Torayuki Okuyama, Masafumi Onodera, Shuji Takada
- Journal Title
  
  Sci Rep
  
  Volume: 13(1) Issue: 1 Pages: 7865-7865
- DOI
  10.1038/s41598-023-34541-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07927
[Journal Article] Enhanced osteoblastic differentiation of parietal bone in a novel murine model of mucopolysaccharidosis type II2023
- Author(s)
  Narutoshi Yamazaki, Mari Ohira, Shuji Takada, Akira Ohtake, Masafumi Onodera, Mahito Nakanishi, Torayuki Okuyama, Ryuichi Mashima
- Journal Title
  
  Mol Genet Metab Rep
  
  Volume: 37 Pages: 101021-101021
- DOI
  10.1016/j.ymgmr.2023.101021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07927
[Journal Article] 質量分析法を利用したライソゾーム病の酵素活性測定について2023
- Author(s)
  真嶋隆一
- Journal Title
  
  日本マススクリーニング学会誌
  
  Volume: 33(3) Pages: 41-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07927
[Journal Article] Physiology and Pathophysiology of Heparan Sulfate in Animal Models: Its Biosynthesis and Degradation2022
- Author(s)
  Ryuichi Mashima, Torayuki Okuyama, Mari Ohira
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23(4) Issue: 4 Pages: 1963-1963
- DOI
  10.3390/ijms23041963
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07952
[Journal Article] Lysosomal Acid Lipase Deficiency: Genetics, Screening, and Preclinical Study2022
- Author(s)
  Ryuichi Mashima, Shuji Takada
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23(24) Issue: 24 Pages: 15549-15549
- DOI
  10.3390/ijms232415549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07927
[Journal Article] Lipid Nanoparticles: A Novel Gene Delivery Technique for Clinical Application2022
- Author(s)
  Ryuichi Mashima, Shuji Takada
- Journal Title
  
  Curr Issues Mol Biol
  
  Volume: 44(10) Issue: 10 Pages: 5013-5027
- DOI
  10.3390/cimb44100341
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07927
[Journal Article] LC-MS/MS-based enzyme assay for lysosomal acid lipase using dried blood spots2022
- Author(s)
  Mari Ohira, Marianne Barr, Torayuki Okuyama, Ryuichi Mashima
- Journal Title
  
  Mol Genet Metab Rep
  
  Volume: 33 Pages: 100913-100913
- DOI
  10.1016/j.ymgmr.2022.100913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07927
[Journal Article] Mammalian Sulfatases: Biochemistry, Disease Manifestation, and Therapy.2022
- Author(s)
  Mashima R, Nakanishi M
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23(15) Issue: 15 Pages: 8153-8153
- DOI
  10.3390/ijms23158153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07927
[Journal Article] Production of therapeutic iduronate-2-sulfatase enzyme with a novel single-stranded RNA virus vector.2021
- Author(s)
  Ohira M, Kikuchi E, Mizuta S, Yoshida N, Onodera M, Nakanishi M, Okuyama T, Mashima R.
- Journal Title
  
  Genes Cells
  
  Volume: 26(11) Pages: 891-904
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07952
[Journal Article] Long-Chain Base (LCB)-Targeted Lipidomics Study Uncovering the Presence of a Variety of LCBs in Mammalian Blood2020
- Author(s)
  Ohira Mari、Okuyama Torayuki、Mashima Ryuichi
- Journal Title
  
  Separations
  
  Volume: 7 Issue: 4 Pages: 57-57
- DOI
  10.3390/separations7040057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07952
[Journal Article] Biomarkers for Lysosomal Storage Disorders with an Emphasis on Mass Spectrometry2020
- Author(s)
  Mashima Ryuichi、Okuyama Torayuki、Ohira Mari
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 8 Pages: 2704-2704
- DOI
  10.3390/ijms21082704
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07952
[Journal Article] The second report on spondyloepimetaphyseal dysplasia, aggrecan type: a milder phenotype than originally reported.2019
- Author(s)
  Fukuhara Y, Cho SY, Miyazaki O, Hattori A, Seo JH, Mashima R, Kosuga M, Fukami M, Jin DK, Okuyama T, Nishimura G.
- Journal Title
  
  Clin Dysmorphol.
  
  Volume: 28(1) Issue: 1 Pages: 26-29
- DOI
  10.1097/mcd.0000000000000241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] Biosynthesis of long chain base in sphingolipids in animals, plants, and fungi.2019
- Author(s)
  Mashima R, Okuyama T, Ohira M.
- Journal Title
  
  Future Sciences OA
  
  Volume: 6(1) Issue: 1
- DOI
  10.2144/fsoa-2019-0094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07952
[Journal Article] Elevation of plasma lysosphingomyelin-509 and urinary bile acid metabolite in Niemann-Pick disease type C-affected individuals2018
- Author(s)
  Mashima R, Maekawa M, Narita A, Okuyama T, Mano N.
- Journal Title
  
  Mol Genet Metab Rep
  
  Volume: 15 Pages: 90-95
- DOI
  10.1016/j.ymgmr.2018.03.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958, KAKENHI-PROJECT-16K20900
[Journal Article] Lipid biomarkers for the peroxisomal and lysosomal disorders: their formation, metabolism and measurement.2018
- Author(s)
  Mashima R, Maekawa M.
- Journal Title
  
  Biomark Med.
  
  Volume: 12(1) Issue: 1 Pages: 83-95
- DOI
  10.2217/bmm-2017-0225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] Elevation of plasma lysosphingomyelin-509 and urinary bile acid metabolite in Niemann-Pick disease type C-affected individuals.2018
- Author(s)
  Mashima R, Maekawa M, Narita A, Okuyama T, Mano N.
- Journal Title
  
  Mol Genet Metab Rep
  
  Volume: 15 Pages: 90-95
- DOI
  10.1016/j.ymgmr.2018.08.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] Quantification of the enzyme activities of iduronate-2-sulfatase, N-acetylgalactosamine-6-sulfatase and N-acetylgalactosamine-4-sulfatase using liquid chromatography-tandem mass spectrometry.2017
- Author(s)
  Mashima R, Ohira M, Okuyama T, Tatsumi A
- Journal Title
  
  Mol Genet Metab Rep
  
  Volume: 14 Pages: 36-40
- DOI
  10.1016/j.ymgmr.2017.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] A molecular analysis of the GAA gene and clinical spectrum in 38 patients with Pompe disease in Japan.2017
- Author(s)
  Fukuhara Y, Fuji N, Yamazaki N, Hirakiyama A, Kamioka T, Seo JH, Mashima R, Kosuga M, Okuyama T.
- Journal Title
  
  Mol Genet Metab Rep
  
  Volume: 14 Pages: 3-9
- DOI
  10.1016/j.ymgmr.2017.10.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] 複数疾患同時測定系によるライソゾーム酵素活性測定法の検討2017
- Author(s)
  真嶋隆一、坂井英里、小須賀基通、奥山虎之
- Journal Title
  
  日本マス・スクリーニング学会誌
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] Enzyme activities of α-glucosidase in Japanese neonates with pseudodeficiency alleles.2017
- Author(s)
  Mashima R, Okuyama T.
- Journal Title
  
  Mol Genet Metab Rep
  
  Volume: 12 Pages: 110-114
- DOI
  10.1016/j.ymgmr.2017.06.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] Aspartylglucosaminuria caused by a novel homozygous mutation in the AGA gene was identified by an exome-first approach in a patient from Japan.2017
- Author(s)
  Yamamoto T, Shimojima K, Matsufuji M, Mashima R, Sakai E, Okuyama T.
- Journal Title
  
  Brain Dev.
  
  Volume: 39(5) Issue: 5 Pages: 422-425
- DOI
  10.1016/j.braindev.2016.12.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24791090, KAKENHI-PROJECT-15K09631, KAKENHI-PROJECT-16K08958, KAKENHI-PROJECT-17J40108
[Journal Article] Molecular diagnosis of 65 families with mucopolysaccharidosis type II (Hunter syndrome) characterized by 16 novel mutations in the IDS gene: Genetic, pathological, and structural studies on iduronate-2-sulfatase.2016
- Author(s)
  Kosuga M, Mashima R, Hirakiyama A, Fuji N, Kumagai T, Seo JH, Nikaido M, Saito S, Ohno K, Sakuraba H, Okuyama T.
- Journal Title
  
  Mol Genet Metab.
  
  Volume: 118 Issue: 3 Pages: 190-197
- DOI
  10.1016/j.ymgme.2016.05.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] The levels of urinary glycosaminoglycans of patients with attenuated and severe type of mucopolysaccharidosis II determined by liquid chromatography-tandem mass spectrometry.2016
- Author(s)
  Mashima R, Sakai E, Tanaka M, Kosuga M, Okuyama T.
- Journal Title
  
  Mol Genet Metab Rep.
  
  Volume: 7 Pages: 87-91
- DOI
  10.1016/j.ymgmr.2016.03.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] A selective detection of lysophosphatidylcholine in dried blood spots for diagnosis of adrenoleukodystrophy by LC-MS/MS.2016
- Author(s)
  Mashima R, Tanaka M, Sakai E, Nakajima H, Kumagai T, Kosuga M, Okuyama T.
- Journal Title
  
  Mol Genet Metab Rep.
  
  Volume: 7 Pages: 16-19
- DOI
  10.1016/j.ymgmr.2016.02.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] Mini review on "Molecular diagnosis of 65 families with mucopolysaccharidosis type II (Hunter syndrome) characterized by 16 novel mutations in the IDS gene: Genetic, pathological, and structural studies on iduronate-2-sulfatase"2016
- Author(s)
  Mashima R, Okuyama T.
- Journal Title
  
  J Rare Dis Res Treat
  
  Volume: 2 Pages: 43-46
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] Levels of enzyme activities in six lysosomal storage diseases in Japanese neonates determined by liquid chromatography-tandem mass spectrometry.2016
- Author(s)
  Mashima R, Sakai E, Tanaka M, Kosuga M, Okuyama T.
- Journal Title
  
  Mol Genet Metab Rep.
  
  Volume: 9 Pages: 6-11
- DOI
  10.1016/j.ymgmr.2016.08.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] 極長鎖脂肪酸含有リン脂質を指標とした高速液体クロマトグラフィー/三連四重極質量分析法（LC/MS/MS）による副腎白質ジストロフィー(ALD)診断法の開発2016
- Author(s)
  田中美砂、真嶋隆一、坂井英里、中島英規、熊谷淳之、小須賀基通、奥山虎之
- Journal Title
  
  日本マス・スクリーニング学会誌
  
  Volume: 26 Pages: 79-84
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08958
[Journal Article] Dok adaptors play anti-inflammatory roles in pulmonary homeostasis.2013
- Author(s)
  Mashima R, Arimura S, Kajikawa S, Oda H, Nakae S, Yamanashi Y.
- Journal Title
  
  Genes to Cells
  
  Volume: 18 Issue: 1 Pages: 56-65
- DOI
  10.1111/gtc.12016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J08500, KAKENHI-PUBLICLY-23117511, KAKENHI-PROJECT-23249013, KAKENHI-PROJECT-23591115, KAKENHI-PROJECT-23657113, KAKENHI-PROJECT-24659520, KAKENHI-PLANNED-23112007
[Journal Article] Dok-1 and Dok-2 deficiency induces osteopenia via regulation of osteoclasts2011
- Author(s)
  Aya Kawamata
- Journal Title
  
  J. Cell. Physiol.
  
  Volume: 226 Issue: 12 Pages: 3087-3093
- DOI
  10.1002/jcp.22909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249013, KAKENHI-PROJECT-23591115, KAKENHI-PROJECT-23659868, KAKENHI-PROJECT-23791628
[Journal Article] Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma.2010
- Author(s)
  Mashima R, Honda K, Yang Y, Morita Y, Inoue A, Arimura S, Nishina H, Ema H, Nakauchi H, Seed B, Oda H, Yamanashi Y
- Journal Title
  
  Laboratory Investigation
  
  Volume: 90 Pages: 1357-1364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014030
[Journal Article] Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive hisitocytic sarcoma2010
- Author(s)
  Ryuichi Mashima, Honda Kazuho, Yi Yang, Yohei Morita, Akane Inoue, Sumimasa Arimura, Hiroshi Nishina, Hideo Ema, Hiromitsu Nakauchi, Brian Seed, Hideaki Oda, and Yuji Yamanashi
- Journal Title
  
  Lab. Investigation
  
  Volume: 90 Pages: 1357-1364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247024
[Journal Article] Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive hisitocytic sarcoma.2010
- Author(s)
  Ryuichi Mashima, Honda Kazuho, Yi Yang, Yohei Morita, Akane Inoue, Sumimasa Arimura, Hiroshi Nishina, Hideo Ema, Hiromitsu Nakauchi, Brian Seed, Hideaki Oda, Yuji Yamanashi.
- Journal Title
  
  Lab.Investigation 90
  
  Pages: 1357-1364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014030
[Journal Article] Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma2010
- Author(s)
  Mashima R., Honda K., Yang Y., Morita Y., Inoue A., Arimura S., Nishina H., Ema H., Nakauchi H., Seed B., Oda H., Yamanashi Y
- Journal Title
  
  Laboratory Investigation
  
  Volume: 90 Pages: 1357-1364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247024
[Journal Article] The roles of Dok family adapters in immunoreceptor signaling2009
- Author(s)
  Mashima R, Hishida Y, Tezuka T, Yamanashi Y
- Journal Title
  
  Immunological Reviews
  
  Volume: 232 Pages: 273-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014030
[Journal Article] The roles of Dok family adaptors in immunoreceptor signaling.2009
- Author(s)
  Ryuichi Mashima, Yukihiro Hishida, Tohru Tezuka, Yuji Yamanashi.
- Journal Title
  
  Immunological Reviews 232
  
  Pages: 273-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014030
[Journal Article] The roles of Dok family adapters in immunoreceptor sigrraling2009
- Author(s)
  Mashima R., Hishida Y., Tezuka T., Yamanashi Y.
- Journal Title
  
  Immunological Reviews
  
  Volume: 232 Pages: 273-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247024
[Journal Article] The roles of Dok family adaptors in immunoreceptor signaling2009
- Author(s)
  Ryuichi Mashima, Yukihiro Hishida, Tohru Tezuka, and Yuji Yamanashi
- Journal Title
  
  Immunological Reviews
  
  Volume: 232 Pages: 273-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247024
[Journal Article] FLN29, a novel interferon-and LPS-inducible gene acting as a negative regulator of Toll-like receptor signaling.2005
- Author(s)
  Ryuichi Mashima, Kazuko Saeki, Daisuke Aki, Yasumasa Minoda, Hiromi Takaki, Takahito Sanada, Takshi Kobayashi, Hiroyuki Aburatani, Yuji Yamanashi, Akihiko Yoshimura.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 41289-41297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014030
[Presentation] ムコ多糖症II型の新しい疾患マウスモデル2023
- Author(s)
  65.真嶋隆一、大平麻里、奥山虎之、小野寺雅史、高田修治
- Organizer
  第64回日本先天代謝異常学会学術集会（大阪）
- Data Source
  KAKENHI-PROJECT-22K07927
[Presentation] ライソゾーム病スクリーニング・診断での質量分析の役割2023
- Author(s)
  真嶋隆一
- Organizer
  第48回日本医用マススペクトル学会年会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K07927
[Presentation] 乾燥濾紙血を使用したライソゾーム酸性リパーゼ酵素活性測定法の検討2022
- Author(s)
  真嶋隆一、大平麻里、Barr M、奥山虎之、Hamilton, J
- Organizer
  第49回日本マススクリーニング学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07927
[Presentation] ライソゾーム酸性リパーゼの酵素活性測定法の検討2022
- Author(s)
  真嶋隆一、大平麻里、Barr M、奥山虎之、Hamilton, J
- Organizer
  第63回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-22K07927
[Presentation] Presence of a variety of long-chain base (LCB) in mammalian blood uncovered by LCB-targeted lipidomics assay2021
- Author(s)
  Mashima R, Ohira M, Okuyama T
- Organizer
  31st International Symposium on Pharmaceutical and Biomedical Analysis (PBA2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] ライソゾーム病スクリーニングに関する最近の話題2021
- Author(s)
  真嶋隆一
- Organizer
  第48回日本マススクリーニング学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] 多重反応モニタリング法による長鎖塩基の解析2021
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Production of therapeutic iduronate-2-sulfatase enzyme with a novel single-stranded RNA vector2021
- Author(s)
  真嶋隆一、大平麻里、菊池亜美花、水田志織、吉田尚美、小野寺雅史、中西真人、奥山虎之
- Organizer
  第27回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Long-chain base (LCB)-targeted lipidomics study revealed the presence of a variety of LCBs in mammalian blood2021
- Author(s)
  Mashima R, Ohira M, Okuyama T,
- Organizer
  69th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] 質量分析で捉える新規臨床バイオマーカー：ライソゾーム病領域における最近の話題2021
- Author(s)
  真嶋隆一、前川正充、大平麻里、眞野成康、奥山虎之
- Organizer
  第68回日本質量分析総合討論会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Presence of a variety of long-chain base (LCB) in mammalian blood uncovered by LCB-targeted lipidomics assay2021
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第33回バイオメディカル分析科学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] ヒト血漿LysoGb3に含まれる長鎖塩基の解析2021
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第46回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Expression of therapeutic iduronate-2-sulfatase enzyme with a novel single-stranded RNA vector2021
- Author(s)
  Mashima R, Ohira M, Kikuchi E, Mizuta S, Yoshida N, Onodera M, Nakanishi M, Okuyama T
- Organizer
  14th International congress of inborn errors of metabolism (ICIEM2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Altered osteoblastogenesis in Ids-deficient mice.2021
- Author(s)
  Yamazaki, N, Mashima R, Onodera M, Nakanishi M, Okuyama T
- Organizer
  18th WORLDSymposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Biochemical assay for NBS in LSD2021
- Author(s)
  Mashima R
- Organizer
  International Lysosomal Disease Web conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Expression of therapeutic iduronate-2-sulfatase enzyme with a novel single-stranded RNA vector2021
- Author(s)
  Mashima R, Ohira M, Kikuchi E, Mizuta S, Yoshida N, Onodera M, Nakanishi M, Okuyama T
- Organizer
  18th WORLDSymposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Expression of therapeutic iduronate-2-sulfatase enzyme with a novel single-stranded RNA vector2021
- Author(s)
  大平麻里、菊池亜美花、水田志織、吉田尚美、小野寺雅史、中西真人、奥山虎之、真嶋隆一
- Organizer
  第62回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Multiplex measurement of LSD enzyme activity using LC-MS/MS.2020
- Author(s)
  Mashima R, Ohira, M, Okuyama T.
- Organizer
  16th WORLDSymposium, Orlando, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] LPC26をバイオマーカーとした副腎白質ジストロフィーの新生児スクリーニングの予備検討2020
- Author(s)
  真嶋隆一、辰巳暁也、大平麻里、奥山虎之
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] 副腎白質ジストロフィーの新生児スクリーニングを目指した予備検討2020
- Author(s)
  真嶋隆一
- Organizer
  第60回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] 質量分析法による11疾患ライソゾーム酵素活性同時測定系の検討2019
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第46回日本マススクリーニング学会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] LC-MS/MSによるライソゾーム病酵素活性の同時測定2019
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第67回日本質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] 質量分析法を用いたヒト血漿LysoGb3の定量分析2019
- Author(s)
  大平麻里、奥山虎之、真嶋隆一
- Organizer
  第24回日本ライソゾーム病研究会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Quantification of 11-plex enzyme activity of lysosomal storage disorders using LC-MS.2019
- Author(s)
  Mashima R, Ohira, M, Okuyama T.
- Organizer
  2019 APHL Newborn Screening and Genetic Testing Symposium, Chicago, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] 質量分析法による11疾患ライソゾーム酵素活性同時測定系の検討2019
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第44回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Quantification of 11 enzyme activities of lysosomal storage disorders using LC-MS/MS.2019
- Author(s)
  Mashima R, Ohira, M, Okuyama T.
- Organizer
  SSIEM Annual symposium 2019, Rotterdam, The Netherlands.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] ライソゾーム酵素原因酵素の同時測定法の検討2019
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第92回生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] 質量分析法による11疾患ライソゾーム酵素活性同時測定系の検討2019
- Author(s)
  真嶋隆一
- Organizer
  第59回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Quantification of 11-plex LSD enzyme activity using liquid chromatography-tandem mass spectrometry2019
- Author(s)
  Mashima R, Ohira, M, Okuyama T
- Organizer
  15th WORLDSymposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Quantification of 11-plex enzyme activity of LSDs using LC-MS/MS.2019
- Author(s)
  Mashima R, Ohira, M, Okuyama T.
- Organizer
  67th Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Quantification of 11 enzyme activities of lysosomal storage disorders by liquid chromatography-tandem mass spectrometry.2019
- Author(s)
  Mashima R, Ohira, M, Okuyama T.
- Organizer
  International Conference on Biology of Lipids, Tokyo, Japan.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] Multiplex-measurement of enzyme activity for lysosomal storage disorders using LC-MS/MS.2019
- Author(s)
  Mashima R, Ohira, M, Okuyama T.
- Organizer
  10th International Society for Neonatal Screening, Hangzhou, China.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] 質量分析法を用いたライソゾーム病原因酵素の酵素活性測定値について2019
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第61回日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-19K07952
[Presentation] ニーマンピック病C型患者血清中のLyso-SM-509とスフィンゴシルホスホリルコリンの同時分析2018
- Author(s)
  神納　勇、前川正充、真嶋隆一、成田　綾、山口浩明、眞野成康
- Organizer
  第31回バイオメディカル分析科学シンポジウム
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] ニーマンピック病C型のバイオマーカーについて2018
- Author(s)
  真嶋隆一、前川正充、成田　綾、奥山虎之、眞野成康、
- Organizer
  第60回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Quantification of the enzyme activities of ID2S, GALN and ARSB using LC-MS/MS2018
- Author(s)
  Mashima R, Ohira M, Okuyama T
- Organizer
  66th Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 質量分析法を利用したファブリー病バイオマーカーの検討2018
- Author(s)
  大平麻里、真嶋隆一、奥山虎之
- Organizer
  第60回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] LC-MS/MSによるライソゾーム病酵素活性の同時測定2018
- Author(s)
  大平麻里、真嶋隆一、奥山虎之
- Organizer
  第60回日本先天代謝異常学会総会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 成育医療における質量分析法の貢献2018
- Author(s)
  真嶋隆一、坂井英里、大平麻里、田中美砂、奥山虎之
- Organizer
  第66回日本質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] LC-MS/MSによるライソゾーム病酵素活性の同時測定：ID2S, GALN,およびARSB酵素活性測定によるMPS II, IVA, VIのスクリーニングへの応用2018
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  第45回日本マススクリーニング学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 質量分析法を使ったライソゾーム酵素活性測定系の検討2018
- Author(s)
  真嶋隆一
- Organizer
  第58回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] LC-MS/MSによるライソゾーム病酵素活性の同時測定：ID2S, GALN,およびARSB酵素活性測定によるMPS II, IVA, VIのスクリーニングへの応用2018
- Author(s)
  真嶋隆一、大平麻里、奥山虎之
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Determination of the enzyme activities of ID2S, GALN and ARSB using LC-MS/MS2018
- Author(s)
  Mashima R, Ohira, M, Okuyama T
- Organizer
  SSIEM 2018 Annual symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] LC-MS/MSによるライソゾーム病酵素活性の同時測定2017
- Author(s)
  真嶋隆一、奥山虎之
- Organizer
  第30回バイオメディカル分析科学シンポジウム
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Quantification of enzyme activities of lysosomal storage disorders in a neonatal population using mass spectrometry2017
- Author(s)
  Mashima R, Okuyama T
- Organizer
  14th WORLDSymposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Enzyme activities in six lysosomal storage diseases in Japanese neonates determined by LC-MS/MS2017
- Author(s)
  Mashima R, Okuyama T
- Organizer
  ICIEM 2017 Rio de Janeiro
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 質量分析法を用いたライソゾーム病複数疾患同時測定系の検討2017
- Author(s)
  真嶋隆一、奥山虎之
- Organizer
  第65回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 質量分析法を用いたライソゾーム病酵素活性測定系の検討2017
- Author(s)
  真嶋隆一、奥山虎之
- Organizer
  第44回日本マススクリーニング学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 質量分析法を利用したライソゾーム病酵素活性測定法について2017
- Author(s)
  真嶋隆一、大平麻里、辰巳暁哉、奥山虎之
- Organizer
  第59回日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 複数のライソゾーム病原因酵素活性の同時測定系の検討2017
- Author(s)
  真嶋隆一、奥山虎之
- Organizer
  第59回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Levels of enzyme activities in six lysosomal storage disorders in random Japanese neonates using LC-MS/MS2017
- Author(s)
  Mashima R, Sakai E, Kosuga M, and Okuyama T
- Organizer
  13th WORLD Symposium
- Place of Presentation
  San Diego, USA
- Year and Date
  2017-02-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Enzyme activities in six lysosomal storage diseases in Japanese neonates determined by LC-MS/MS2017
- Author(s)
  Mashima R, Kosuga M, and Okuyama T
- Organizer
  65th Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Enzyme activities of LSDs in a Japanese neonatal population2017
- Author(s)
  Mashima R
- Organizer
  APHL Newborn Screening and Genetic Testing Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] A selective detection of lysophosphatidylcholine in dried blood spot for diagnosis of adrenoleukodystrophy by LC-MS/MS2016
- Author(s)
  Mashima R, Tanaka M, Sakai E, Kumagai T, Kosuga M, Okuyama T
- Organizer
  The 13th International Congress of Human Genetics 2016
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] LC-MS/MSを用いたムコ多糖症患者の尿中グリコサミノグリカンの測定2016
- Author(s)
  坂井英里、真嶋隆一、田中美砂、小須賀基通、奥山虎之
- Organizer
  第58回日本先天代謝異常学会総会
- Place of Presentation
  東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] X-連鎖型副腎白質ジストロフィーの臨床検査法の開発：極長鎖脂肪酸をバイオマーカーとして2016
- Author(s)
  真嶋隆一、田中美砂、坂井英里、熊谷淳之、小須賀基通、奥山虎之
- Organizer
  第29回バイオメディカル分析科学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 臨床検査学的に応用可能な極長鎖脂肪酸をバイオマーカーとした副腎白質ジストロフィーの診断法の開発2016
- Author(s)
  真嶋隆一、田中美砂、坂井英里、中島英規、熊谷淳之、小須賀基通、奥山虎之、
- Organizer
  第64回質量分析総合討論会
- Place of Presentation
  大阪
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] LC-MS/MSによるライソゾーム酵素活性測定法の検討2016
- Author(s)
  真嶋隆一、坂井英里、田中美砂、小須賀基通、奥山虎之
- Organizer
  第58回日本先天代謝異常学会総会
- Place of Presentation
  東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 極長鎖脂肪酸をバイオマーカーとしたX-連鎖型副腎白質ジストロフィーの臨床検査法の開発2016
- Author(s)
  真嶋隆一、田中美砂、坂井英里、小須賀基通、奥山虎之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Blood lysophosphatidylcholine demonstrates as a diagnostic marker for X-linked adrenoleukodystrophy2016
- Author(s)
  Mashima R, Tanaka M, Sakai E, Kumagai T, Kosuga M, Okuyama T
- Organizer
  SSIEM Rome 2016
- Place of Presentation
  Rome, Italy
- Year and Date
  2016-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] ムコ多糖症II型の原因遺伝子であるIDS遺伝子の日本人家系における解析例：16の新規変異を含む65例の解析結果2016
- Author(s)
  真嶋隆一、小須賀基通、櫻庭均、奥山虎之
- Organizer
  第21回ライソゾーム病研究会
- Place of Presentation
  東京
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Levels of enzyme activities in six lysosomal storage disorders in random Japanese neonates using LC-MS/MS2016
- Author(s)
  Mashima R
- Organizer
  5th Asian Congress for LSD Screening
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 多疾患同時測定系によるライソゾーム酵素活性測定法の検討2016
- Author(s)
  真嶋隆一、坂井英里、小須賀基通、奥山虎之
- Organizer
  第43回日本マス・スクリーニング学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] エクソーム解析で明らかになったアスパルチルグルコサミン尿症2016
- Author(s)
  山本俊至、下島圭子、松藤まゆみ、真嶋隆一、坂井英里、奥山虎之
- Organizer
  第58回日本先天代謝異常学会総会
- Place of Presentation
  東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 臨床検査学的に有用である極長鎖脂肪酸をバイオマーカーとした副腎白質ジストロフィー診断法の開発2016
- Author(s)
  真嶋隆一、田中美砂、坂井英里、熊谷淳之、小須賀基通、奥山虎之
- Organizer
  第58回日本脂質生化学会
- Place of Presentation
  秋田
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] 極長鎖脂肪酸をバイオマーカーとした副腎白質ジストロフィーの臨床検査法の開発2016
- Author(s)
  真嶋隆一、田中美砂、坂井英里、中島英規、熊谷淳之、小須賀基通、奥山虎之
- Organizer
  第41回日本医用マススペクトル学会年会
- Place of Presentation
  名古屋
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-16K08958
[Presentation] Role of Wnt5a-Ror signaling in morphogenesis of the metanephric mesenchyme during ureteric budding2015
- Author(s)
  Michiru Nishita, Sen Qiao, Xiaoyuan Qi, Mari Miyamoto, Yuka Okinaka, Makiko Yamada, Ryuju Hashimoto, Kazumoto Iijima, Hiroki Otani, Christine Hartmann, Ryuichi Nishinakamura, Yasuhiro Minami
- Organizer
  新学術領域研究「上皮管腔組織形成」第２回国際シンポジウム
- Place of Presentation
  北海道大学（札幌、北海道）
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112007
[Presentation] Role of Wnt5a-Ror2 signaling in patterning the metanephric mesenchyme during ureteric budding2014
- Author(s)
  Michiru Nishita, Sen Qiao, Mari Miyamoto, Yuka Okinaka, Makiko Yamada, Ryuju Hashimoto, Kazumoto Iijima, Hiroki Otani, Christine Hartmann, Ryuichi Nishinakamura, Yasuhiro Minami
- Organizer
  Keystone Symposia "Developmental Pathways and Cancer: Wnt, Notch and Hedgehog(J7)"
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PLANNED-23112007
[Presentation] Roles of Wnt/PCP signaling in pathological conditions of epithelial tubular tissues2013
- Author(s)
  Yasuhiro Minami, Kaoru Yamagata, Mitsuharu Endo, Hiroki Otani, Ryuichi Nishinakamura, Michiru Nishita
- Organizer
  First International Meeting for Epithelial Tubulology
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PLANNED-23112007
[]

1. YAMANASHI Yuji (40202387)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. HIGUCHI Osamu (50361720)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. MINAMI YASUHIRO (70229772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. TEZUKA Toru (50312319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAE Susumu (60450409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIMOJIMA Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MASHIMA RYUICHI 真嶋 隆一

MASHIMA Ryuichi 真嶋 隆一

Research Projects

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Co-Researchers

ライソゾーム酸性リパーゼ欠損症疾患マウスモデルの病態解析と治療法の開発Principal Investigator

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病態モデルマウスを利用したムコ多糖症発症メカニズムの解明と治療法の開発Principal Investigator

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Development of clinical assay for LSDs using LC-MS/MSPrincipal Investigator

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Development of screening and diagnostic assay for mucopolysaccharidosis type IIPrincipal Investigator

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Dysfunction of planar cell polarity signaling and its relationship with ciliopathies and cancer invasion and metastasis

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The role of Dok adaptors in pulmonary disordersPrincipal Investigator

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Molecular signaling in neuromuscular synaptogenesis, hematopoiesis, and related disorders

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Role of receptor tyrosine kinases in hematopoietic cellsPrincipal Investigator

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Protein kinase signaling and malignant cell proliferation

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Dok-mediated regulation of cellular functions

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[Journal Article] RNA-Based Therapeutic Technology.2023

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[Journal Article] A novel mucopolysaccharidosis type II mouse model with an iduronate-2-sulfatase-P88L mutation2023

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[Journal Article] Enhanced osteoblastic differentiation of parietal bone in a novel murine model of mucopolysaccharidosis type II2023

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MASHIMA RYUICHI 真嶋隆一

MASHIMA Ryuichi 真嶋隆一