TSUMOTO Hiroki 津元裕樹

… Alternative Names

津元裕樹ツモトヒロキ

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Researcher Number	00409385
Other IDs	https://orcid.org/0009-0002-9717-739X
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 主任研究員
Affiliation (based on the past Project Information) *help	2023: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 主任研究員 2021: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 主任研究員 2016 – 2020: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2015: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 老化機構研究チーム, 研究員 2013 – 2014: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 … More 2012: 名古屋市立大学, 大学院・薬学研究科, 特任助教 2011: 京都大学, 大学院・薬学研究科, 特定助教 2010 – 2011: 京都大学, 薬学研究科, 特定助教 Less
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Physical pharmacy / Drug development chemistry Except Principal Investigator Health science and related fields / Human pathology / Drug development chemistry
Keywords	Principal Investigator 質量分析 / 誘導体化 / シアル酸 / 糖ペプチド / 糖鎖 / グライコプロテオミクス / プロテオミクス / O-GlcNAc / 分析化学 / プロテオーム / S-ニトロシル化 / ニトロキシル / 生物活性物質 … More Except Principal Investigator … More プロテオーム / バイオマーカー / 糖鎖 / 認知症 / グライコミクス / プロテオミクス / 縦断コホート / 認知機能 / 糖尿病 / 動脈解離症 / 老化 / 動脈 / 酸化還元 / 細胞・組織 / 分析科学 / ストレス / 有機化学 / 薬学 / 活性酸素種 / 生物活性物質 Less

Development and application of high-throughput glycoproteomics using sialic acid linkage specific derivatizationPrincipal Investigator
- Principal Investigator
  
  津元裕樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of a method for analysis of sialyl glycans and glycopeptides using sialic acid linkage-specific derivatizationPrincipal Investigator
- Principal Investigator
  
  Tsumoto Hiroki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of diagnostic marker and preventive strategy for diabetic dementia
- Principal Investigator
  
  Iwamoto Machiko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Health science and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of a method for the analysis of protein O-GlcNAcylation using two-step click chemistryPrincipal Investigator
- Principal Investigator
  
  Tsumoto Hiroki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Proteomic and pathological analyses of arterial aging and aortic dissection, especially focused on expression and posttranslational modification of the proteins
- Principal Investigator
  
  SAWABE Motoji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Development of specific and sensitive method for analysis of protein S-nitrosylation using mass spectrometryPrincipal Investigator
- Principal Investigator
  
  TSUMOTO HIROKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Oxidative stress imaging in organelle by novel TEMPO derivatives
- Principal Investigator
  
  NAKAGAWA Hidehiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagoya City University
Development of specific and highly sensitive method to detect nitroxyl by mass spectrometryPrincipal Investigator
- Principal Investigator
  
  TSUMOTO Hiroki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University

All 2022 2021 2020 2019 2018 2017 2015 2010 Other

All Journal Article Presentation Patent

[Journal Article] Glycomics for healthy aging2020
- Author(s)
  三浦ゆり、津元裕樹、遠藤玉夫
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 3 Pages: 343-348
- DOI
  10.14952/SEIKAGAKU.2020.920343
- ISSN
  0037-1017
- Year and Date
  2020-06-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07025, KAKENHI-PROJECT-19K11736
[Journal Article] Comparative Glycomic Analysis of Sialyl Linkage Isomers by Sialic Acid Linkage-Specific Alkylamidation in Combination with Stable Isotope Labeling of α2,3-Linked Sialic Acid Residues2019
- Author(s)
  Hanamatsu Hisatoshi、Nishikaze Takashi、Tsumoto Hiroki、Ogawa Koji、Kobayashi Takashi、Yokota Ikuko、Morikawa Kenichi、Suda Goki、Sho Takuya、Nakai Masato、Miura Nobuaki、Higashino Kenichi、Sekiya Sadanori、Iwamoto Shinichi、Miura Yuri、Furukawa Jun-ichi、Tanaka Koichi、Sakamoto Naoya
- Journal Title
  
  Analytical Chemistry
  
  Volume: 91 Issue: 21 Pages: 13343-13348
- DOI
  10.1021/acs.analchem.9b03617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07025, KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-19K15597, KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-18K19530, KAKENHI-PROJECT-16K19324
[Journal Article] Quantitative analysis of O-GlcNAcylation in combination with isobaric tag labeling and chemoenzymatic enrichment2017
- Author(s)
  Hiroki Tsumoto, Yoshihiro Akimoto, Tamao Endo, Yuri Miura.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 22 Pages: 5022-5026
- DOI
  10.1016/j.bmcl.2017.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08219
[Journal Article] Development of a DNA-binding TEMPO derivative for evaluation of nuclear oxidative stress and its application in living cells2010
- Author(s)
  Mamiko Ikeda, Hidehiko Nakagawa, Shizuka Ban, Hiroki Tsumoto, Takayoshi Suzuki, and Naoki Miyata
- Journal Title
  
  Free Radic. Biol. Med
  
  Volume: 49 Issue: 11 Pages: 1792-1797
- DOI
  10.1016/j.freeradbiomed.2010.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590103
[Patent] 質量分析方法、質量分析装置およびプログラム2019
- Inventor(s)
  西風隆司，津元裕樹
- Industrial Property Rights Holder
  西風隆司，津元裕樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-135344
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K07025
[Presentation] N-Glycan profiling in plasma proteins of semi-supercentenarians using sialic acid linkage-specific derivatization and negative-ion MALDI-TOF MS2022
- Author(s)
  Hiroki Tsumoto, Mako Inuzuka, Takashi Nishikaze, Yusaku Hioki, Md. Amir Hossen, Yasumichi Arai, Kazunori Ikebe, Tatsuro Ishizaki, Kei Kamide, Yasuyuki Gondo, Yukie Masui, Nobuyoshi Hirose, Yoshihiro Hayakawa, Yuri Miura, Tamao Endo
- Organizer
  70th ASMS Conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07025
[Presentation] シアル酸結合様式特異的誘導体化法を用いた超百寿者の血漿N-グライコプロテオミクス2022
- Author(s)
  津元裕樹，西風隆司，新井康通，池邉一典，石崎達郎，神出計，権藤恭之，増井幸恵，梅澤啓太郎，川上恭司郎，広瀬信義，早川禎宏，三浦ゆり，遠藤玉夫
- Organizer
  第70回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-19K07025
[Presentation] シアル酸結合様式特異的誘導体化法を用いたヒト血漿タンパク質の糖ペプチド解析．2021
- Author(s)
  3.津元裕樹，西風隆司，梅澤啓太郎，川上恭司郎，早川禎宏，三浦ゆり，遠藤玉夫．
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K07025
[Presentation] 安定同位体を用いたSALSA法による比較質量分析法の開発．2020
- Author(s)
  花松久寿, 西風隆司, 津元裕樹, 小川浩司, 横田育子, 森川賢一, 須田剛生, 庄拓也, 中井正人, 三浦信明, 関谷禎規, 岩本慎一, 三浦ゆり, 田中耕一, 坂本直哉, 古川潤一．
- Organizer
  第39回日本糖質学会年会．
- Data Source
  KAKENHI-PROJECT-19K07025
[Presentation] 血しょうタンパク質糖鎖修飾の健康寿命延伸を目指したバイオマーカーとしての可能性．2020
- Author(s)
  三浦ゆり, 川上恭司郎, 井出野佑太, 増井幸恵, 稲垣宏樹, 小野口航, 津元裕樹, 梅澤啓太郎, 新井康通, 池邉一典, 石崎達郎, 神出計, 権藤恭之, 遠藤玉夫．
- Organizer
  第71回日本電気泳動学会総会．
- Data Source
  KAKENHI-PROJECT-19K07025
[Presentation] シアル酸結合様式特異的誘導体化法を用いたO-結合型糖ペプチド解析法の開発．2020
- Author(s)
  津元裕樹，西風隆司，関谷禎規，梅澤啓太郎，川上恭司郎，岩本慎一，田中耕一，三浦ゆり，遠藤玉夫．
- Organizer
  第68回質量分析総合討論会．
- Data Source
  KAKENHI-PROJECT-19K07025
[Presentation] シアル酸結合様式特異的誘導体化法を用いた糖ペプチド解析法の開発2019
- Author(s)
  津元裕樹, 西風隆司, 関谷禎規, 岩本慎一, 田中耕一, 三浦ゆり, 遠藤玉夫.
- Organizer
  日本プロテオーム学会2019年大会・第70回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-19K07025
[Presentation] 糖尿病モデルGoto-Kakizakiラット腎組織における線維化2018
- Author(s)
  三浦ゆり，早川敦子，津元裕樹，岩本真知子，福井浩二，秋元義弘，遠藤玉夫
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会（MSP2018）
- Data Source
  KAKENHI-PROJECT-16K08219
[Presentation] ラット腎臓におけるリン酸化アクチンと糖修飾アクチンの局在2018
- Author(s)
  秋元義弘，楊國昌，三浦ゆり，津元裕樹，岩本真知子，戸田年総，福冨俊之，菅原大介，宮東昭彦，Gerald W Hart，遠藤玉夫，川上速人
- Organizer
  第59回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K08219
[Presentation] Sirtuin 1（SIRT1）のO-GlcNAc 修飾に関する研究2018
- Author(s)
  尾﨑友祥，津元裕樹，岩本真知子，梅澤啓太郎，福井浩二，秋元義弘，遠藤玉夫，三浦ゆり
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16K08219
[Presentation] 効率的なO-GlcNAc 化ペプチド濃縮のための担体の比較2017
- Author(s)
  津元裕樹, 秋元義弘, 遠藤玉夫, 三浦ゆり
- Organizer
  日本薬学会第137年会（仙台）
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08219
[Presentation] 高齢者の縦断調査血液サンプルを用いた初期の認知機能低下に関するプロテオミクス解析2017
- Author(s)
  7.三浦ゆり、岩本真知子、稲垣宏樹、増井幸恵、石岡良子、津元裕樹、樺山舞、杉本研、阿部由紀子、新井康通、神出計、池邉一典、石崎達郎、権藤恭之、高橋龍太郎、遠藤玉夫
- Organizer
  第68回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-17K19950
[Presentation] ヒト大動脈中膜の老化プロテオミクス2015
- Author(s)
  津元裕樹, 岩本真知子, 兼平茜, 副島友莉恵, 新井冨生, 濱松晶彦, 遠藤玉夫, 沢辺元司, 三浦ゆり
- Organizer
  第57 回日本老年医学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-26460432
[Presentation] ヒト大動脈解離症のプロテオーム解析
- Author(s)
  三浦ゆり, 岩本真知子, 津元裕樹, 副島友莉恵, 戸田年総, 森澤　拓, 新井冨生, 濱松晶彦, 遠藤玉夫, 沢辺元司
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26460432
[Presentation] ヒト大動脈老化のプロテオーム解析
- Author(s)
  三浦ゆり, 岩本真知子, 津元裕樹, 副島友莉恵, 戸田年総, 森澤　拓, 新井冨生, 濱松晶彦, 遠藤玉夫, 沢辺元司
- Organizer
  第65回日本電気泳動学会総会
- Place of Presentation
  横浜情報文化センター
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26460432

1. 三浦ゆり (00216574)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. NAKAGAWA Hidehiko (80281674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. MIYATA Naoki (50114674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. SUZUKI Takayoshi (90372838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SAWABE Motoji (30196331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. Iwamoto Machiko (40167284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 副島友莉恵 (60596964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

TSUMOTO Hiroki 津元 裕樹

津元 裕樹 ツモト ヒロキ

Research Projects

Research Products

Co-Researchers

Development and application of high-throughput glycoproteomics using sialic acid linkage specific derivatizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a method for analysis of sialyl glycans and glycopeptides using sialic acid linkage-specific derivatizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of diagnostic marker and preventive strategy for diabetic dementia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a method for the analysis of protein O-GlcNAcylation using two-step click chemistryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proteomic and pathological analyses of arterial aging and aortic dissection, especially focused on expression and posttranslational modification of the proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of specific and sensitive method for analysis of protein S-nitrosylation using mass spectrometryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Oxidative stress imaging in organelle by novel TEMPO derivatives

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of specific and highly sensitive method to detect nitroxyl by mass spectrometryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Glycomics for healthy aging2020

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Comparative Glycomic Analysis of Sialyl Linkage Isomers by Sialic Acid Linkage-Specific Alkylamidation in Combination with Stable Isotope Labeling of α2,3-Linked Sialic Acid Residues2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantitative analysis of O-GlcNAcylation in combination with isobaric tag labeling and chemoenzymatic enrichment2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a DNA-binding TEMPO derivative for evaluation of nuclear oxidative stress and its application in living cells2010

Author(s)

Journal Title

DOI

Data Source

[Patent] 質量分析方法、質量分析装置およびプログラム2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

TSUMOTO Hiroki 津元裕樹

津元裕樹ツモトヒロキ