Yukihiro Ohno 大野行弘

… Alternative Names

大野行弘オオノユキヒロ

OHNO Yukihiro 大野行弘

大野行宏オオノユキヒロ

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Researcher Number	00432534
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 大阪医科薬科大学, 薬学部, 教授 2020: 大阪薬科大学, 薬学部, 准教授 2018 – 2019: 大阪薬科大学, 薬学部, 教授 2017: 大阪薬科大学, 薬学部, 准教授 2016 – 2017: 大阪薬科大学, 薬学部, 教授(移行) … More 2014 – 2016: 大阪薬科大学, 薬学部, 教授 2011 – 2012: 大阪薬科大学, 薬学部, 教授 2008 – 2011: 大阪薬科大学, 薬学部, 准教授 2009: 大阪薬科学大学, 薬学部, 准教授 Less
Review Section/Research Field	Principal Investigator Pharmacology in pharmacy / Basic Section 47040:Pharmacology-related / Biological pharmacy Except Principal Investigator Laboratory animal science / Basic Section 52020:Neurology-related / Psychiatric science
Keywords	Principal Investigator てんかん / 精神疾患 / GABA遊離 / シナプス小胞蛋白SV2A / シナプス分泌 / アストロサイト / 不安障害 / けいれん発作 / うつ病 / 神経疾患 … More / 認知機能障害 / 抑うつ・不安障害 / 空間的カリウム緩衝機構 / 内向き整流性Kir4.1チャネル / メタンフェタミン / 攻撃行動 / 情動障害 / 幼若期隔離飼育ストレス / プレパルス・インヒビション / 驚愕反応試験 / Fosタンパク質発現 / マイクロダイアリシス / シナプス小胞タンパク質（SV2A） / ミスセンス変異 / 統合失調症 / ドパミン遊離 / 側坐核 / 精神障害 / シナプス小胞タンパク質２A（SV2A) / 動物モデル / シナプス小胞蛋白2A (SV2A) / グルタミン酸 / 開口分泌 / シナプス小胞タンパク2A　（SV2A) / シナプス / 大脳辺縁系 / GABA / 神経伝達物質 / キンドリング / てんかん原性 / シナプトタグミン１ / 扁桃体 / 疾患モデル / 抗てんかん薬 / 欠神発作 / 強直-間代発作 / カリウム緩衝機構 / 内向き整流性カリウムチャネル / 薬理学 … More Except Principal Investigator てんかん / グリア / 疾患モデル / ラット / active DC電位 / Kir4.1チャンネル / 数学的力学系分類 / 時定数 / 数理モデル / 脳波 / 深層学習 / TIRDA / 発作時HFO / 発作時DC電位 / red slow / HFO / DC電位 / wide-band EEG / グリア細胞 / ニューロン / 開口分泌 / 機能性疾患 / ADHD / 認知症 / 統合失調症 / 三者間伝達 / アストロサイト / 行動薬理 / チャネル拮抗薬 / HCN1 / ポジショナルクローニング / ミュータント / 下オリーブ核 / HCN1チャネル / アスパルトアシラーゼ / 順遺伝学 / 本態性振戦 / 亜系統 / BACクローン / 遺伝解析 / コンジェニック系統 / NER / 原因遺伝子 Less

Analysis of the mechanisms underlying development of neuropsychiatric diseases with focus on astrocytic potassium buffering functionPrincipal Investigator
- Principal Investigator
  
  Ohno Yukihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Comprehensive epileptic network analysis in human brain by neuron and glia
- Principal Investigator
  
  Ikeda Akio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyoto University
Pathophysiological mechanism of mental disorders associated with dysfunction of synaptic releasePrincipal Investigator
- Principal Investigator
  
  Ohno Yukihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
Mechanisms of tripartite synaptic transmission
- Principal Investigator
  
  Okada Motohiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
Pathophysiological analysis of epilepsy with focusing on the synaptic release mechanismPrincipal Investigator
- Principal Investigator
  
  Yukihiro Ohno
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
Epilepsy research focusing on the potassium buffering function of brain astrocytesPrincipal Investigator
- Principal Investigator
  
  OHNO Yukihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
Identification of genetic components in a rat model of essential tremor
- Principal Investigator
  
  KURAMOTO Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
Elucidation of the genetic factors in rat epileptic seizures
- Principal Investigator
  
  SERIKAWA Tadao
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University

[Book] Serotonin receptors as the therapeutic target for central nervous system disorders. In "Serotonin: The Mediator That Spans Evolution"　edited by P.M. Pilowsky2019
- Author(s)
  Yukihiro Ohno
- Total Pages
  430
- Publisher
  Elsevier
- ISBN
  9780128000502
- Data Source
  KAKENHI-PROJECT-17K08324
[Book] Serotonin：The mediator that spans evolution2019
- Author(s)
  Y. Ohno
- Total Pages
  430
- Publisher
  Elsevier
- ISBN
  9780128000502
- Data Source
  KAKENHI-PROJECT-17K08324
[Book] In Vivo Neuropharmacology and Neurophysiology2016
- Author(s)
  H.A. Iha, N. Kunisawa, K. Tokudome, T. Mukai, M. Kinboshi,　S. Shimizu, Y. Ohno
- Publisher
  Springer Science+Business Media, LLC, New York
- Data Source
  KAKENHI-PROJECT-26460111
[Journal Article] Enhanced phase-amplitude coupling of human electrocorticography selectively in the posterior cortical region during rapid eye movement sleep2022
- Author(s)
  Togawa Jumpei、Matsumoto Riki、Usami Kiyohide、Matsuhashi Masao、Inouchi Morito、Kobayashi Katsuya、Hitomi Takefumi、Nakae Takuro、Shimotake Akihiro、Yamao Yukihiro、Kikuchi Takayuki、Yoshida Kazumichi、Kunieda Takeharu、Miyamoto Susumu、Takahashi Ryosuke、Ikeda Akio
- Journal Title
  
  Cerebral Cortex
  
  Volume: - Issue: 2 Pages: 486-496
- DOI
  10.1093/cercor/bhac079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18424, KAKENHI-PUBLICLY-20H05471, KAKENHI-PROJECT-18H02709, KAKENHI-PROJECT-20K16492, KAKENHI-PROJECT-20K07902, KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-22K15729, KAKENHI-PROJECT-19K17033, KAKENHI-PROJECT-19H03574, KAKENHI-PUBLICLY-22H04777
[Journal Article] Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor2022
- Author(s)
  Masaki Kato, Naofumi Kunisawa, Saki Shimizu, Higor A. Iha, Yukihiro Ohno
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 938175-938175
- DOI
  10.3389/fphar.2022.938175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06587, KAKENHI-PROJECT-21K15278
[Journal Article] Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma2022
- Author(s)
  Masaya Ueda, Kiyohide Usami, Yukihiro Yamao, Rie Yamawaki, Chinatsu Umaba, Nan Liang, Manabu Nankaku, Yohei Mineharu, Masayuki Honda, Takefumi Hitomi, Ryosuke Ikeguchi, Akio Ikeda, Susumu Miyamoto, Shuichi Matsuda, Yoshiki Arakawa
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 18302-18302
- DOI
  10.1038/s41598-022-22493-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-22K21212, KAKENHI-PROJECT-19H03974, KAKENHI-PROJECT-19H03574, KAKENHI-PROJECT-20K16492
[Journal Article] Effects of a stable concentration of propofol on interictal high-frequency oscillations in drug-resistant epilepsy2021
- Author(s)
  Inada Taku、Kobayashi Katsuya、Kikuchi Takayuki、Matsuhashi Masao、Matsumoto Riki、Takahashi Yuki、Nakae Takuro、Shibata Sumiya、Yamao Yukihiro、Daifu Masako、Togawa Jumpei、Yoshida Kazumichi、Kunieda Takeharu、Kobayashi Katsuhiro、Ikeda Akio、Miyamoto Susumu
- Journal Title
  
  Epileptic Disorders
  
  Volume: 23 Issue: 2 Pages: 299-312
- DOI
  10.1684/epd.2021.1264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18424, KAKENHI-PROJECT-19H01091, KAKENHI-PROJECT-19H03574, KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-21K17671
[Journal Article] Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases.2021
- Author(s)
  Y. Ohno, N. Kunisawa, S. Shimizu
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 19 Pages: 10236-10236
- DOI
  10.3390/ijms221910236
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16384, KAKENHI-PROJECT-21K06587, KAKENHI-PROJECT-21K15278
[Journal Article] Connectivity Gradient in the Human Left Inferior Frontal Gyrus: Intraoperative Cortico-Cortical Evoked Potential Study2020
- Author(s)
  Takuro Nakae, Riki Matsumoto, Takeharu Kunieda, Yoshiki Arakawa, Katsuya Kobayashi, Akihiro Shimotake, Yukihiro Yamao, Takayuki Kikuchi, Toshihiko Aso, Masao Matsuhashi, Kazumichi Yoshida, Akio Ikeda, Ryosuke Takahashi, Matthew A Lambon Ralph, Susumu Miyamoto
- Journal Title
  
  Cerebral Cortex
  
  Volume: - Issue: 8 Pages: 4633-4650
- DOI
  10.1093/cercor/bhaa065
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-17K10892, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-19K09480, KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-19K17033, KAKENHI-PROJECT-19K18424, KAKENHI-PROJECT-18K19514, KAKENHI-PUBLICLY-20H05471, KAKENHI-PROJECT-19H01091, KAKENHI-PROJECT-18H02709, KAKENHI-PROJECT-19H03574
[Journal Article] Mechanism Underlying Organophosphate Paraoxon-Induced Kinetic Tremor.2019
- Author(s)
  Iha HA, Kunisawa N, Shimizu S, Onishi M, Nomura Y, Matsubara N, Iwai C, Ogawa M, Hashimura M, Sato K, Kato M, Ohno Y.
- Journal Title
  
  Neurotox Res.
  
  Volume: 35 Issue: 3 Pages: 575-583
- DOI
  10.1007/s12640-019-0007-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21501, KAKENHI-PROJECT-17K08324
[Journal Article] Antipsychotic Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD): Management of Extrapyramidal Side Effects2019
- Author(s)
  Y. Ohno, N. Kunisawa, S. Shimizu
- Journal Title
  
  Front. Pharmacol.
  
  Volume: 10
- DOI
  10.3389/fphar.2019.01045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324
[Journal Article] Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in Leucine-Rich Glioma-Inactivated 1 (Lgi1) Mutant Rats.2019
- Author(s)
  Masato Kinboshi , Saki Shimizu, Tomoji Mashimo, Tadao Serikawa, Hidefumi Ito, Akio Ikeda, Ryosuke Takahashi, Yukihiro Ohno
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 5 Pages: 001-015
- DOI
  10.3390/ijms20051013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-16K21501, KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-19H03574
[Journal Article] Astrocytic Kir4.1 potassium channels as a novel therapeutic target for epilepsy and mood disorders.2018
- Author(s)
  Y. Ohno
- Journal Title
  
  Neural Regeneration Research
  
  Volume: 13 Issue: 4 Pages: 651-652
- DOI
  10.4103/1673-5374.230355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324
[Journal Article] Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents.2018
- Author(s)
  N. Kunisawa, S. Shimizu, M. Kato, H. A. Iha, C. Iwai, M. Hashimura, M. Ogawa, S. Kawaji, K. Kawakita, K. Abe, Y. Ohno
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 137 Issue: 2 Pages: 162-169
- DOI
  10.1016/j.jphs.2018.05.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-16K21501
[Journal Article] Function of synaptic vesicle protein 2A (SV2A) as a novel therapeutic target for epilepsy2018
- Author(s)
  徳留健太郎、清水佐紀、芹川忠夫、大野行弘
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 152 Issue: 6 Pages: 275-280
- DOI
  10.1254/fpj.152.275
- NAID
  130007528441
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324
[Journal Article] Antiepileptic drugs elevate astrocytic Kir4.1 expression in the rat limbic region.2018
- Author(s)
  T. Mukai, M. Kinboshi, Y. Nagao, S. Shimizu, A. Ono, Y. Sakagami, A. Okuda, M. Fujimoto, H. Ito, A. Ikeda, Y. Ohno
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 9 Pages: 845-845
- DOI
  10.3389/fphar.2018.00845
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874
[Journal Article] Inwardly rectifying potassium channel Kir4.1 as a novel modulator of BDNF expression in astrocytes.2018
- Author(s)
  Y. Ohno, M. Kinboshi, S. Shimizu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 11 Pages: 3313-3313
- DOI
  10.3390/ijms19113313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-16K21501
[Journal Article] Therapeutic role of synaptic vesicle glycoprotein 2A (SV2A) in modulating epileptogenesis.2017
- Author(s)
  Y. Ohno, K. Tokudome
- Journal Title
  
  CNS Neurol Disord Drug Targets
  
  Volume: 16 Issue: 4 Pages: 463-471
- DOI
  10.2174/1871527316666170404115027
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460111
[Journal Article] Serotonergic modulation of nicotine-induced kinetic tremor in mice2017
- Author(s)
  Kunisawa Naofumi、Iha Higor A.、Nomura Yuji、Onishi Misaki、Matsubara Nami、Shimizu Saki、Ohno Yukihiro
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 134 Issue: 2 Pages: 131-138
- DOI
  10.1016/j.jphs.2017.06.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-16K21501
[Journal Article] Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes2017
- Author(s)
  Kinboshi Masato、Mukai Takahiro、Nagao Yuki、Matsuba Yusuke、Tsuji Yoshimi、Tanaka Shiho、Tokudome Kentaro、Shimizu Saki、Ito Hidefumi、Ikeda Akio、Inanobe Atsushi、Kurachi Yoshihisa、Inoue Seiji、Ohno Yukihiro
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 10 Pages: 408-408
- DOI
  10.3389/fnmol.2017.00408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-16K21501, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-15H04270, KAKENHI-PROJECT-15K09351, KAKENHI-PROJECT-17H04018
[Journal Article] Nicotine elicits convulsive seizures by activating amygdalar neurons.2017
- Author(s)
  Iha HA, Kunisawa N, Shimizu S, Tokudome K, Mukai T, Kinboshi M, Ikeda A, Ito H, Serikawa T, Ohno Y
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 8 Pages: 57-57
- DOI
  10.3389/fphar.2017.00057
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-15H04270, KAKENHI-PROJECT-26293209, KAKENHI-PROJECT-26460111, KAKENHI-PROJECT-16K21501, KAKENHI-INTERNATIONAL-15K21731
[Journal Article] Nicotine evokes kinetic tremor by activating the inferior olive via α7 nicotinic acetylcholine receptors.2016
- Author(s)
  N. Kunisawa, H. A. Iha, S. Shimizu, K. Tokudome, T. Mukai, M. Kinboshi, T. Serikawa, Y. Ohno: Nicotine evokes kinetic tremor by activating the inferior olive via α7 nicotinic acetyl
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 314 Pages: 173-180
- DOI
  10.1016/j.bbr.2016.08.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460111, KAKENHI-PROJECT-16K21501
[Journal Article] Immunohistochemical analysis of Fos protein expression for exploring brain regions related to central nervous system disorders and drug actions.2016
- Author(s)
  H.A. Iha, N. Kunisawa, K. Tokudome, T. Mukai, M. Kinboshi,　S. Shimizu, Y. Ohno
- Journal Title
  
  Neuromethods
  
  Volume: 121 Pages: 389-408
- DOI
  10.1007/978-1-4939-6490-1_17
- ISBN
  9781493964888, 9781493964901
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460111, KAKENHI-PROJECT-16K21501
[Journal Article] Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission.2016
- Author(s)
  Tokudome K, Okumura T, Shimizu S, Mashimo T, Takizawa A, Serikawa T, Terada R, Ishihara S, Kunisawa N, Sasa M, Ohno Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 2742-2742
- DOI
  10.1038/srep27420
- NAID
  120006349333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26460111
[Journal Article] A Missense Mutation of the Gene Encoding Synaptic Vesicle Glycoprotein 2A (SV2A) Confers Seizure Susceptibility by Disrupting Amygdalar Synaptic GABA Release.2016
- Author(s)
  Tokudome K, Okumura T, Terada R, Shimizu S, Kunisawa N, Mashimo T, Serikawa T, Sasa M, Ohno Y.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 7 Pages: 210-210
- DOI
  10.3389/fphar.2016.00210
- NAID
  120006331984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26460111
[Journal Article] New insight into the therapeutic role of the serotonergic system in Parkinson’s disease2015
- Author(s)
  Y. Ohno, S. Shimizu, K. Tokudome, N. Kunisawa, M. Sasa
- Journal Title
  
  Progress in Neurobiology
  
  Volume: 134 Pages: 104-121
- DOI
  10.1016/j.pneurobio.2015.09.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460111
[Journal Article] Expressional analysis of inwardly rectifying Kir4.1 channels in Noda epileptic rat (NER)2013
- Author(s)
  Yuya Harada, Yuki Nagao, Saki Shimizu, Tadao Serikawa, Ryo Terada, Megumi Fujimoto, Aoi Okuda, Takahiro Mukai, Masashi Sasa, Yoshihisa Kurachi, Yukihiro Ohno
- Journal Title
  
  Brain Research
  
  Volume: 1517 Pages: 141-149
- DOI
  10.1016/j.brainres.2013.04.009
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136002, KAKENHI-PROJECT-22590092
[Journal Article] Expressional analysis of the astrocytic Kir4.1 channel in a pilocarpine-induced temporal lobe epilepsy model.2013
- Author(s)
  Yuki Nagao, Yuya. Harada, Takahiro Mukai,Saki Shimizu, Aoi Okuda, Megumi Fujimoto,Asuka Ono, Yoshihisa Sakagami,Yukihiro
- Journal Title
  
  Front. Cell. Neurosci.
  
  Volume: 7 Pages: 104-104
- DOI
  10.3389/fncel.2013.00104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590092
[Journal Article] Kindling-associated SV2A expression in hilar GABAergic interneurons of the mouse dentate gyrus2012
- Author(s)
  Y.Ohno, et al
- Journal Title
  
  Neurosci.Lett
  
  Volume: 510 Issue: 2 Pages: 93-98
- DOI
  10.1016/j.neulet.2012.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042, KAKENHI-PROJECT-22590092
[Journal Article] Scnla missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures2011
- Author(s)
  Y.Ohno, et al
- Journal Title
  
  Neurobiol.Dis
  
  Volume: 41 Issue: 2 Pages: 261-269
- DOI
  10.1016/j.nbd.2010.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042, KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-22590092
[Journal Article] Serotonergic modulation of extrapyramidal motor disorders in mice and rats : Role of striatal 5-HT_3 and 5-HT_6 receptors2011
- Author(s)
  Ohno Y, et al
- Journal Title
  
  Neuropharmacology
  
  Volume: 60 Issue: 2-3 Pages: 201-208
- DOI
  10.1016/j.neuropharm.2010.08.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590092
[Journal Article] Scn1a missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures.2011
- Author(s)
  Ohno Y, et al.
- Journal Title
  
  Neurobiol Dis
  
  Volume: 41 Pages: 261-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590092
[Journal Article] Scnla missense mutation impairs GABA_A receptor-mediated synaptic transmission in the rat hippocampus2010
- Author(s)
  Ohno Y, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400 Pages: 117-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Scn1a missense mutation impairs GABAA receptor-mediated synaptic transmission in the rat hippocampus2010
- Author(s)
  Ohno Y, Sofue N, Ishihara S, Mashimo T, Sasa M, Serikawa T
- Journal Title
  
  Biophys Res Commun
  
  Volume: 400(1) Pages: 117-122
- URL
  http://dx.doi.org/10.1016/j.bbrc.2010.08.021
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] A missense mutation of the geneencoding voltage-dependent sodiumchannel (Nav1.1) confers susceptibility tofebrile seizures in rats.2010
- Author(s)
  Mashimo T, Ohmori I, Ouchida M,Ohno Y, Tsurumi T, Miki T, Wakamori M,Ishihara S, Yoshida T, Takizawa A, Kato M,Hirabayashi M, Sasa M, Mori Y, SerikawaT.
- Journal Title
  
  J Neurosci 30
  
  Pages: 5744-5753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Scn1a missense mutation impairs GABA_A receptor-mediated synaptic transmission in the rat hippocampus.2010
- Author(s)
  Ohno Y, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400 Pages: 117-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590092
[Journal Article] Scnla missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures.2010
- Author(s)
  Ohno Y, et al.
- Journal Title
  
  Neurobiol Dis
  
  Volume: 41 Pages: 261-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] A missense mutation of the gene encoding voltage-dependent sodium channel(Nav1. 1) confers susce ptibility to febrile seizures in rats2010
- Author(s)
  Mashimo T, Ohmori I, Ouchida M, Ohno Y, Tsurumi T, Miki T, Wakamori M, Ishihara S, Yoshida T, Takizawa A, Kato M, Hirabayashi M, Sasa M, Mori Y, Serikawa T
- Journal Title
  
  J Neurosci
  
  Volume: 30(16) Issue: 16 Pages: 5744-5753
- DOI
  10.1523/jneurosci.3360-09.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042, KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-22659335
[Journal Article] Antiepileptogenic andanticonvulsive actions of levetiracetam in apentylenetetrazole kindling model.2010
- Author(s)
  Ohno Y, Ishihara S, Terada R, SerikawaT, Sasa M.
- Journal Title
  
  Epilepsy Res 89
  
  Pages: 360-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Serotonergic modulation of absence-like seizures in Groggy rats : a novel rat model of absence epilepsy.2010
- Author(s)
  Ohno Y, et al.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 114 Pages: 99-105
- NAID
  10029889960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590092
[Journal Article] Scn1a missense mutation causes limbic hype rexcitability and vulne rability to expe rimental febrile seizures2010
- Author(s)
  Ohno Y, Ishihara S, Mashimo T, Sofue N, Shimizu S, Imaoku T, Tsurumi T, Sasa M, Serikawa T
- Journal Title
  
  Neurobiol Dis
  
  Volume: 41(2) Pages: 261-269
- URL
  http://dx.doi.org/10.1016/j.nbd.2010.09.013
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Serotonergic Modulation of Absence-Like Seizures in Groggy Rats: a Novel Rat Model of Absence Epilepsy2010
- Author(s)
  Yukihiro Ohno, Nobumasa Sofue, TakujiImaoku, Eri Morishita, Kenta Kumafuji, MasashiSasa, Tadao Serikawa
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 114 Issue: 1 Pages: 99-105
- DOI
  10.1254/jphs.10156FP
- NAID
  10029889960
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590092
[Journal Article] Scn1a missense mutation impairs GABA(A) receptor-mediated synaptic transmission in the rat hippocampus.2010
- Author(s)
  Ohno Y, Sofue N, Ishihara S, Mashimo T, Sasa M, Serikawa T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400(1) Issue: 1 Pages: 117-22
- DOI
  10.1016/j.bbrc.2010.08.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-22590092
[Journal Article] Antiepileptogenic and anticonvulsive actions of levetiracetam in a pentylenetetrazole kindling model.2010
- Author(s)
  Ohno Y, et al.
- Journal Title
  
  Epilepsy Research
  
  Volume: 89 Pages: 360-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Serotonergic Modulation of Absence-Like Seizures in Groggy Rats : a Novel Rat Model of Absence Epilepsy.2010
- Author(s)
  Ohno Y, et al.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 114 Pages: 99-105
- NAID
  10029889960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Regional expression of Fos-like immunoreactivity following seizures in Noda epileptic rat (NER)2009
- Author(s)
  Y.Ohno, et al.
- Journal Title
  
  Epilepsy Research 87
  
  Pages: 70-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Re gional expression of Fos-like immuno reactivity following seizures in Noda epileptic rat(NER)2009
- Author(s)
  Ohno Y, Shimizu S, Harada Y, Morishita M, Ishihara S, Kumafuji K, Sasa M, Serikawa T
- Journal Title
  
  Epilepsy Res
  
  Volume: 87(1) Pages: 70-76
- URL
  http://dx.doi.org/10.1016/j.eplepsyres.2009.07.012
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Regional expression ofFos-like immunoreactivity followingseizures in Noda epileptic rat (NER).2009
- Author(s)
  Ohno Y, Shimizu S, Harada Y,Morishita M, Ishihara S, Kumafuji K, SasaM, Serikawa T.
- Journal Title
  
  Epilepsy Res. 87
  
  Pages: 70-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Preferential increase in the hippocampalsynaptic vesicle protein 2A (SV2A) bypentylenetetrazole kindling.2009
- Author(s)
  Ohno Y, Ishihara S, Terada R, KikutaM, Sofue N, Kawai Y, Serikawa T, Sasa M.
- Journal Title
  
  BiochemBiophys Res Commun 390
  
  Pages: 415-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Kir4.1チャネル阻害薬quinacrineの抗うつ効果におけるアストロサイトの関与2024
- Author(s)
  日下綾菜、石﨑悠斗、井上莉歩、楠野将也、清水佐紀、大野行弘
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] フルオロクエン酸によるアストロサイトの不活性化がペンチレンテトラゾール誘発けいれんに及ぼす影響2024
- Author(s)
  國澤直史、清水佐紀、大野行弘
- Organizer
  第144回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Kir4.1チャネル阻害薬quinacrineの神経炎症を伴う認知機能障害に対する改善作用2024
- Author(s)
  石崎悠斗、清水佐紀、妹尾帆夏、田原拓真、大野行弘
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] 抗LGI1抗体の海馬内投与マウスにおけるけいれん感受性の評価2023
- Author(s)
  菊池絵理、清水佐紀、石崎悠斗、高橋良輔、池田昭夫、大野行弘
- Organizer
  第53回臨床神経生理学会学術大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] ニコチンによる運動興奮症状発現におけるアストロサイト活性化の役割2023
- Author(s)
  河田千佳、國澤直史、後藤光佑、江原澪、清水佐紀、大野行弘
- Organizer
  第73回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Effects of the intrahippocampal injection of anti-Lgi1 antibody on cognitive function and seizure susceptibility in mice2023
- Author(s)
  Eri Kikuchi,, Saki Shimizu, Yuto Ishizaki, Akihiro Shimotake, Kiyohide Usami, Masao Matsuhashi, Ryosuke Takahashi, Akio Ikeda, Yukihiro Ohno
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] コルチコステロン慢性投与マウスのうつ様症状に対するKir4.1チャネル阻害薬の作用評価2023
- Author(s)
  清水佐紀、堀名宏紀、中野諒子、廣瀬由佳、大野行弘
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] ニコチンによる運動興奮症状の発現におけるアストロサイトの関与2023
- Author(s)
  國澤直史、江原澪、河田千佳、後藤光佑、清水佐紀、大野行弘
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] ニコチンによる運動興奮症状に対するアストロサイト選択的抑制剤フルオロクエン酸の影響2023
- Author(s)
  國澤直史、加藤将貴、小田明奈、白川美波、坂口茉鈴、清水佐紀、大野行弘
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] フルオロクエン酸投与によるアストロサイト不活性化モデルの作成2023
- Author(s)
  後藤光佑、國澤直史、河田千佳、江原澪、清水佐紀、大野行弘
- Organizer
  第73回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Effects of the Kir4.1 blocker, quinacrine,　on lipopolysaccharide-induced cognitive impairment2023
- Author(s)
  Yuto Ishizaki, Saki Shimizu, Honatsu Seo, Takuma Tahara, Yukihiro Ohno
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] A Case Presentation of MRI-Negative Left Parietal Lobe Epilepsy2022
- Author(s)
  Yuki Kawamura, Katsuya Kobayashi, Maya Tojima, Yukihiro Yamao, Kiyohide Usami, Akihiro Shimotake, Takayuki Kikuchi, Masao Matsuhashi, Kazumichi Yoshida, Ryosuke Takahashi, Akio Ikeda
- Organizer
  第52回日本臨床神経生理学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] アストロサイト選択的抑制剤フルオロクエン酸の内向き整流性Kir4.1チャネル発現およびペンチレンテトラゾールけいれん感受性に対する作用評価2022
- Author(s)
  國澤直史、加藤将貴、髙田和志、豊桝美沙、藤原安哉子、清水佐紀、大野行弘
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Lipopolysaccharideによる神経炎症性アルツハイマー病モデルの確立2022
- Author(s)
  毎田愛莉、清水佐紀、石﨑悠斗、森山芽衣、宮越樹里、佐納　匠、大野行弘
- Organizer
  第72回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] AI auto-detection of ictal DC shift to facilitate its clinical application as a surrogate biomarker for epilepsy surgery2022
- Author(s)
  Masahiro Gotoh, Katsuya Kobayashi, Masao Matsuhashi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Keiichi Ueda, Takao Namiki, Ichiro Tsuda, Ryosuke Takahashi, Akio Ikeda
- Organizer
  第52回日本臨床神経生理学会学術大会
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] Kir4.1チャネル遮断薬quinacrineによる急性うつ病モデルマウスを用いた抗うつ効果の評価2022
- Author(s)
  清水佐紀、中村義弘、日垣愛生、東野いずみ、石﨑悠斗、大野行弘
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Slow and infraslow of wide-band EEG is related with transient neurological event (TNE) in Moyamoya disease2022
- Author(s)
  Kozue Hayashi, Kiyohide Usami, Masaya Togo, Yukihiro Yamao, Akihiro Shimotake, Takeshi Funaki, Takefumi Hitomi, Takayuki Kikuchi, Masao Matsuhashi, Kazumichi Yoshida, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] Specific Consistency Score (SCS) for epilepsy surgery candidates: Approaches for a simple and useful score for indicating epilepsy surgery2022
- Author(s)
  Maya Tojima, Akihiro Shimotake, Shuichiro Neshige, Tadashi Okada, Katsuya Kobayashi, Kiyohide Usami, Masao Matsuhashi, Takeshi Yoshida, Yasutaka Fushimi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Takao Namiki, Riki Matsumoto, Takeharu Kunieda, Ryosuke Takahashi, Susumu Miyamoto, Akio Ikeda
- Organizer
  14th Asian and Oceanian Epilepsy Congress
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] Evaluation of the effects of Kir4.1 channel inhibitors on lipopolysaccharide-induced depressive behavior2022
- Author(s)
  Saki Shimizu, Ryoko Nakano, Yuka Hirose, Kouki Horina, Yukihiro Ohno
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Specific Consistency Score (SCS) for epilepsy surgery candidates2022
- Author(s)
  Maya Tojima, Akihiro Shimotake, Shuichiro Neshige, Tadashi Okada, Katsuya Kobayashi, Kiyohide Usami, Masao Matsuhashi, Takeshi Yoshida, Yasutaka Fushimi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Takao Namiki, Riki Matsumoto, Takeharu Kunieda, Ryosuke Takahashi, Susumu Miyamoto, Akio Ikeda
- Organizer
  16th Asian Epilepsy Surgery Congress
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] Pentylenetetrazole誘発けいれんに対するアストロサイト選択的阻害剤フルオロクエン酸の影響2022
- Author(s)
  國澤直史、加藤将貴、髙田和志、豊桝美沙、藤原安哉子、清水佐紀、大野行弘
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Lipopolysaccharide誘発急性うつ症状に対するKir4.1チャネル阻害薬の作用評価2022
- Author(s)
  廣瀬由佳、中野諒子、堀名宏紀、清水佐紀、大野行弘
- Organizer
  第72回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] ニコチンによる運動興奮症状におけるアストロサイトの関与2022
- Author(s)
  國澤直史、加藤将貴、小田明奈、白川美波、坂口茉鈴、清水佐紀、大野行弘
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] How to combine MEG date before epilepsy surgery: A scoring system of MEG data with other modalities (SCS-M) improves outcome prediction2022
- Author(s)
  Tadashi Okada, Maya Tojima, Yuto Mitsuno, Akihiro Shimotake, Shuichiro Neshige, Kiyohide Usami, Masao Matsuhashi, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Riki Matsumoto, Takeharu Kunieda, Takao Namiki, Ryosuke Takahashi, Susumu Miyamoto, Akio Ikeda
- Organizer
  14th Asian and Oceanian Epilepsy Congress
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] 強制水泳試験を用いた内向き整流性カリウムチャネルKir4.1阻害薬の抗うつ作用評価2021
- Author(s)
  清水佐紀、日垣愛生、中村義弘、東野いずみ、石﨑悠斗、大野行弘
- Organizer
  第71回日本薬学会関西支部総会
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] 難治性てんかんにおいて細胞外K濃度の変動状態が発作発現に関与する可能性2021
- Author(s)
  後藤昌広, 梶川駿介, 宇佐美清英, 下竹昭寛, 小林勝哉, 人見健文, 山尾幸広, 菊池隆幸, 吉田和道, 宮本享, 松橋眞生, 大野行弘, 髙橋良輔, 池田昭夫
- Organizer
  第16回日本てんかん学会近畿地方会
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] マウス強制水泳試験を用いたKir4.1チャネル阻害薬による抗うつ効果の評価2021
- Author(s)
  日垣愛生、中村義弘、東野いずみ、石﨑悠斗、清水佐紀、大野行弘
- Organizer
  生体機能と創薬シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06587
[Presentation] Exogeneous input to the epileptic focus modulates high frequency activities at the site of stimulation: a direct single pulse stimulation study2020
- Author(s)
  Shunsuke Kajikawa, Riki Matsumoto, Katsuya Kobayashi, Masao Matsuhashi, Tadashi Okada, Mayumi Otani, Masaya Togo, Hirofumi Takeyama, Kiyohide Usami, Akihiro Shimotake, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Ryosuke Takahashi, Akio Ikeda
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] 臨床てんかん患者で、細胞外K濃度の変動状態が発作発現に関与する可能性2020
- Author(s)
  後藤昌広, 梶川駿介, 宇佐美清英, 下竹昭寛, 人見健文, 山尾幸広, 菊池隆幸, 吉田和道, 宮本享, 松橋眞生, 大野行弘, 髙橋良輔, 池田昭夫
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] ISA is associated with transient cortical dysfunction and hyperperfusion in Moyamoya disease2020
- Author(s)
  Hayashi Kozue, Masaya Togo, Kiyohide Usami, Yukihiro Yamao, Akihiro Shimotake, Takefumi Hitomi, Takayuki Kikuchi, Masao Matsuhashi, Kazumichi Yoshida, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] Mechanism of organophosphate paraoxon-induced kinetic tremor in mice2019
- Author(s)
  Yukihiro Ohno, Chihiro Iwai, Higor Alves Iha, Naofumi Kunisawa, Saki Shimizu, Masaki Kato, Mizuki Ogawa, Mai Hashimura
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] てんかんと精神機能調節におけるSV2Aの役割2019
- Author(s)
  大野行弘
- Organizer
  第3回Kinki Epilepsy Summit
- Invited
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Glutamate and GABA release in audiogenic seizure-susceptible, Lgi1 mutant rats2019
- Author(s)
  Masato Kinboshi, Kazuaki Sato, Saki Shimizu, Tadao Serikawa, Hidefumi Ito, Akio Ikeda, Yukihiro Ohno
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Inferior olive is a causative site of the organophosphate paraoxon-induced kinetic tremor2019
- Author(s)
  Higor Alves Iha, Naofumi Kunisawa, Masaki Kato, Saki Shimizu, Misaki Onishi, Yuji Nomura, Nami Matsubara, Chihiro Iwai, Mizuki Ogawa, Aoi Iwamoto, Rina Machida, Kazuaki Sato, Yukihiro Ohno
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Evaluation of glutamate and GABA release in Lgi1 mutant rats susceptible to audiogenic seizures2019
- Author(s)
  Masato Kinboshi, Kazuaki Sato, Saki Shimizu, Tadao Serikawa, Hidefumi Ito, Akio Ikeda, Yukihiro Ohno
- Organizer
  第53回日本てんかん学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Mechanisms underlying the pathogenesis and treatment of neurological disorders: Extrapyramidal motor disorders2019
- Author(s)
  Yukihiro Ohno, Saki Shimizu
- Organizer
  第92回日本薬理学会年会（日本薬理学会・日本毒性学会共催シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Cluster analysis can help classify the ictal direct current (DC) shifts into 2 types2019
- Author(s)
  Shunsuke Kajikawa, Masao Matsuhashi, Katsuya Kobayashi, Takefumi Hitomi, Masako Daifu, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Takao Namiki, Ichiro Tsuda, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda
- Organizer
  第60回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] Ictal direct current (DC) shifts can be classified with 2 patterns: Comparison of ictal DC shifts between time constant 10 sec and 2 sec: attempt of classification with cluster analysis2019
- Author(s)
  Shunsuke Kajikawa, Masao Matsuhashi, Katsuya Kobayashi, Takefumi Hitomi, Masako Daifu, Yukihiro Yamao, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Takao Namiki, Ichiro Tsuda, Riki Matumoto, Ryosuke Takahashi, Akio Ikeda
- Organizer
  American Clinical Neuophysiology Society, 2019 Annual Meeting and Courses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03574
[Presentation] Pharmacological actions of antiepileptic drugs: From first generation to future generation drugs2019
- Author(s)
  Yukihiro Ohno
- Organizer
  第53回日本てんかん学会学術集会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Dysfunction of Sv2A elicites dopaminergic hyperactivity via interacting accumbal GABAergic neurons in rats2019
- Author(s)
  Yukihiro Ohno, Kentaro Tokudome, Ayako Ikari, Yumiko Iguchi, Takafumi Sugahara, Naofumi Kunisawa, Masaki Kato, Tadao Serikawa, Saki Shimizu
- Organizer
  The 2019 International society of neurochemistry (ISN)-American society of neurochemistry (ASN) Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Susceptibility to juvenile isolation stress-induced aggressive behaviors in synaptic vesicle protein 2A (SV2A)-mutant rats2018
- Author(s)
  Kentaro Tokudome, Saki Shimizu, Kanako Ohnishi, Azusa Shimada, Toshihiro Tanaka, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第18回国際薬理学・臨床薬理学会議（WCP2018）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] 幼弱期隔離飼育ストレスによる社会性行動へ及ぼすシナプス小胞蛋白質SV2Aの影響2018
- Author(s)
  清水佐紀、徳留健太郎、大西奏子、嶋田梓、田中敏博、芹川忠夫、大野行弘
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Susceptibility to methamphetamine-induced hyperactivity in synaptic vesicle protein 2A (SV2A)-mutant rats2018
- Author(s)
  Saki Shimizu, Kentaro Tokudome, Ayako Ikari, Yumiko Iguchi, Takafumi Sugahara, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第18回国際薬理学・臨床薬理学会議（WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] 発作原性、ニューロン、グリア2018
- Author(s)
  大野行弘
- Organizer
  第52回日本てんかん学会学術集会　シンポジウム（グルタミン酸とAMPA受容体～基礎と臨床のtranslatability～）
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] 幼弱期隔離飼育ストレスによる社会性行動へ及ぼすシナプス小胞蛋白質SV2Aの影響2018
- Author(s)
  清水佐紀、徳留健太郎、大西奏子、嶋田梓、田中敏博、芹川忠夫、大野行弘
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Synaptic vesicle protein 2A (SV2A) regulates the susceptibility to methamphetamine-induced hyperactivity in rats2018
- Author(s)
  Saki Shimizu, Kentaro Tokudome, Ayako Ikari, Yumiko Iguchi, Takafumi Sugahara, Tadao Serikawa, Yukihiro Ohno
- Organizer
  The International College of Neuropsychopharmacology 2018 (CINP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] グリアとてんかん：アストロサイト Kir4.1 チャネルの病態解析を中心に2017
- Author(s)
  大野行弘、福田敦夫、岡田元宏、小泉修一
- Organizer
  第５１回　日本てんかん学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04892
[Presentation] シナプス小胞蛋白質SV2A変異ラットにおける幼若期隔離飼育ストレス誘発行動の発現変化2017
- Author(s)
  大西奏子、嶋田　梓、田中敏博、徳留健太郎、清水佐紀、芹川忠夫、大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Role of synaptic vesicle glycoprotein 2A (SV2A) in modulating epileptogenesis.2017
- Author(s)
  Yukihiro Ohno
- Organizer
  5th Congress of AsCNP
- Place of Presentation
  Indonesia (Bali)
- Year and Date
  2017-04-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Function of Synaptic Vesicle Glycoprotein 2A as a Novel Therapeutic Target for Epilepsy2017
- Author(s)
  Yukihiro Ohno
- Organizer
  第90回日本薬理学会総会（シンポジウム：てんかん研究の最前線－新たな治療薬を求めて）
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Invited
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] 若年期隔離ストレス負荷による社会性行動変化に対するシナプス小胞蛋白質SV2A遺伝子変異の影響2017
- Author(s)
  徳留健太郎、大西奏子、嶋田梓、田中敏博、清水佐紀、芹川忠夫、大野行弘
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] シナプス小胞蛋白質SV2Aの機能低下は幼若期隔離飼育ストレスによる情動障害を悪化させる2017
- Author(s)
  田中敏博、大西奏子、嶋田　梓、徳留健太郎、清水佐紀、芹川忠夫、大野行弘
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Role of synaptic vesicle glycoprotein 2A (SV2A) in modulating epileptogenesis.2017
- Author(s)
  Yukihiro Ohno
- Organizer
  5th Asian College of Neuropsychopharmacology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08324
[Presentation] Acute nicotine causes convulsive seizures by activating amygdala neurons, primarily through α7nACh receptors2016
- Author(s)
  Higor A. Iha、國澤直史、清水佐紀、熱田侑大、野原孝紀、吉川健斗、徳留健太郎、大野行弘
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] シナプス小胞蛋白SV2A遺伝子変異ラットにおける扁桃核の興奮メカニズム解析2016
- Author(s)
  徳留健太郎、奥村貴裕、國澤直史、清水佐紀、金星匡人、玉田真弓、藤原汐里、三宅梨沙、芹川忠夫、真下知士、笹征史、大野行弘
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Nicotine elicits limbic motor seizures primarily by activating amygdala neurons2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yudai Atsuta, Takanori Nohara, Keito Yoshikawa, Kentaro Tokudome and Yukihiro Ohno
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] シナプス小胞蛋白SV2Aの遺伝子変異による扁桃核の興奮メカニズム2016
- Author(s)
  三宅梨沙、玉田真弓、藤原汐里、徳留健太郎、芹川忠夫、清水佐紀、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Analysis of causative brain regions for nicotine-induced seizures.2016
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Nicotine evokes convulsive seizures by activating amygdala neurons partly through α7nACh receptors.2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa and Yukihiro Ohno
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] A missense mutation of the synaptic vesicle glycoprotein 2A (SV2A) gene confers seizure susceptibility by disrupting amygdala GABA release.2016
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Naofumi Kunisawa, Saki Shimizu, Masato Kinboshi, Mayu Tamada, Shiori Fujiwara, Risa Miyake, Tadao Serikawa, Tomoji Mashimo, Masashi Sasa, Yukihiro Ohno
- Organizer
  第50回日本てんかん学会学術集会
- Place of Presentation
  静岡
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Analysis of causative brain regions for nicotine-induced seizures2016
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Enhancement of the accumbal dopamine release by the gene mutation of synaptic vesicle protein 2A (Sv2aL174Q)2016
- Author(s)
  Kentaro Tokudome, Saki Shimizu, Naofumi Kunisawa, Azuki Hashimoto, Yuki Hiraoka, Kazuki Fukuda, Ayako Ikari, Yumiko Iguchi, Takafumi Sugahara, Tadao Serikawa, Yukihiro Ohno
- Organizer
  The 30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチン誘発振戦におけるセロトニン受容体の関与2016
- Author(s)
  野村有治、尾西美咲、松原菜美、國澤直史、Higor A. Iha、清水佐紀、河合悦子、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Facilitation of kindling development by the gene mutation of synaptic vesicle protein 2A2016
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Naofumi Kunisawa, Saki Shimizu, Ryo Terada1, Masato Kinboshi, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Enhancement of the accumbal dopamine release by the gene mutation of synaptic vesicle protein 2A (Sv2aL174Q).2016
- Author(s)
  Kentaro Tokudome, Saki Shimizu, Naofumi Kunisawa, Azuki Hashimoto, Yuki Hiraoka, Kazuki Fukuda, Ayako Ikari, Yumiko Iguchi, Takafumi Sugahara, Tadao Serikawa, Yukihiro Ohno
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Facilitation of kindling development by the gene mutation of synaptic vesicle protein 2A.2016
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Naofumi Kunisawa, Saki Shimizu, Ryo Terada, Masato Kinboshi, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Pharmacological analysis of nicotine-induced tremor2016
- Author(s)
  Naofumi Kunisawa, Higor A. Iha, Saki Shimizu, Yudai Atsuta, Takanori Nohara, Kento Yoshikawa, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] シナプス分泌機構に着目したてんかん病態解析：シナプス小胞蛋白SV2Aとてんかん原性.2016
- Author(s)
  大野行弘
- Organizer
  第50回日本てんかん学会学術集会　(シンポジウム：てんかん原性についての基礎研究：臨床に役立つ知見））
- Place of Presentation
  静岡
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Nicotine evokes convulsive seizures by activating amygdala neurons partly through α7nACh receptors2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takanori Nohara, Yudai Atsuta, Keito Yoshikawa, Kentaro Tokudome, Masato Kinboshi, Tadao Serikawa and Yukihiro Ohno
- Organizer
  The 30th CINP World congress of Neuropsychopharmacology
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチンによる運動興奮症状の発現メカニズム解析2016
- Author(s)
  國澤直史、Higor A. Iha、清水佐紀、尾西美咲、野村有治、松原菜美、徳留健太郎、河合悦子、大野行弘
- Organizer
  第66回日本薬学会近畿支部総会
- Place of Presentation
  大阪
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Pharmacological responses of nicotine-induced tremor to various anti-tremor agents.2016
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yudai Atsuta, Takanori Nohara, Kento Yoshikawa, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国（ソウル）
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Amygdala is the primary causative site for nicotine-induced convulsive seizures2015
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  第38回日本神経科学会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチン誘発けいれんの原因部位およびメカニズムの解析2015
- Author(s)
  國澤直史、清水佐紀、Higor A. Iha、大高美幸、近持壽郎、高久保佑一、熱田侑大、野原孝紀、吉川健斗、徳留健太郎、河合悦子、大野行弘
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  金沢
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Mutation of the gene encoding synaptic vesicle protein 2A (SV2A) markedly facilitates the kindling epileptogenesis in rats2015
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Naofumi Kunisawa, Saki Shimizu, Ryo Terada, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  The 4th Congress of Asian College of Neuropsychopharmacology
- Place of Presentation
  台湾（台北）
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Mechanisms underlying the kindling facilitation by the gene mutation of synaptic vesicle protein 2A (SV2A)2015
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Naofumi Kunisawa, Kinboshi Masato, Saki Shimizu, Tomoji Mashimo, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第49回日本てんかん学会
- Place of Presentation
  長崎
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Mutation of the gene encoding synaptic vesicle protein 2A (SV2A) markedly facilitates the kindling epileptogenesis in rats2015
- Author(s)
  Naofumi Kunisawa, Kentaro Tokudome, Takahiro Okumura, Saki Shimizu, Masato Kinboshi, Tomoji Mashimo, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第49回日本てんかん学会
- Place of Presentation
  長崎
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Nicotine provokes seizures by activating amygdala neurons partly through α7-nACh receptors2015
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Masato Kinboshi, Yukihiro Ohno
- Organizer
  第49回日本てんかん学会
- Place of Presentation
  長崎
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] アストロサイトの空間的カリウム緩衝機能とてんかん病態2013
- Author(s)
  大野行弘
- Organizer
  第47回日本てんかん学会学術集会シンポジウム
- Place of Presentation
  小倉
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 内向き整流性カリウムチャネルKir4.1の脳内発現に対する抗てんかん薬反復投与の影響.2013
- Author(s)
  大野行弘
- Organizer
  日本薬学会第 133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Expression analysis of astrocytic Kir4.1 channels in pentylentetrazol-induced kindling model.2013
- Author(s)
  Yukihiro Ohno
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 内向き整流性カリウムチャネル Kir4.1 の脳内発現に対する抗てんかん薬反復投与の影響.2013
- Author(s)
  長尾侑紀、向井崇浩、小野朝香、阪上嘉久、清水佐紀、大野行弘
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 欠神発作モデル Groggyラットにおけるシナプス小胞タンパク SV2Aの病態変化2012
- Author(s)
  徳留健太郎、奥村貴裕、清水佐紀、寺田亮、北宅良祐、冨田知里、田中智也、芹川忠夫、笹征史、大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 全般性強直間代発作発現における扁桃核アストロサイト内向き整流性カリウムチャネル Kir4.1 の関与.2012
- Author(s)
  長尾侑紀、原田悠耶、向井崇浩、奥田葵、藤本恵、清水佐紀、芹川忠夫、笹征史、大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] LGI1 変異ラット音刺激誘発けいれんモデルにおける c-Fos 免疫染色による解析2012
- Author(s)
  麓直浩、真下知士、増井淳、水口裕登、南本翔子、石田紗恵子、池田昭夫、高橋良輔、大野行弘、芹川忠夫
- Organizer
  第116回関西実験動物研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Expression analysis of astrocytic Kir4.1 channels in a rat model of temporal lobe epilepsy2012
- Author(s)
  大野行弘
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 内向き整流性カリウムチャネル Kir4.1 発現に及ぼす各種抗てんかん薬の影響.2012
- Author(s)
  阪上嘉久、長尾侑紀、向井崇浩、小野朝香、奥田葵、藤本恵、清水佐紀、大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム
- Place of Presentation
  神戸 A
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] アストロサイト内向き整流性カリウムチャネル Kir4.1 のけいれん病態における発現変化 -NER (Noda epileptic rat)を用いた検討-2012
- Author(s)
  長尾侑紀、原田悠耶、向井崇浩、奥田葵、藤本恵、清水佐紀、河合悦子、芹川忠夫、笹征史、大野行弘
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Increases in astrocytic Kir4.1 channel expression by antiepileptic treatments2012
- Author(s)
  大野行弘
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pathophysiological alterations of synaptic vesicle protein 2A (SV2A) in Groggy rat, a rat model of absence seizure2012
- Author(s)
  大野行弘
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Expression analysis ofastrocytic Kir4.1 channels in a rat model of temporal lobe epilepsy2012
- Author(s)
  Takahiro Mukai, Yuki Nagao, Yuya Harada,Aoi Okuda, Megumi Fujimoto, Asuka Ono,Yoshihisa Sakagami, Saki Shimizu, YoshikoKawai, Yukihiro Ohno
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] アストロサイト内向き整流性カリウムチャネルKir4.1のけいれん病態における発現変化－NER (Noda epileptic rat)を用いた検討－2012
- Author(s)
  大野行弘
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Expression analysis of astrocytic Kir4.1 channelsin pentylentetrazol-induced kindling model2012
- Author(s)
  Takahiro Mukai, Yuki Nagao, Asuka Ono,Yoshihisa Sakagami, Aoi Okuda, MegumiFujimoto, Saki Shimizu, Yukihiro Ohno
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] LGI1 変異ラット音刺激誘発けいれんモデルにおける c-Fos 免疫染色による解析2012
- Author(s)
  麓直浩、真下知士、増井淳、水口祐登、南本翔子、石田紗恵子、池田昭夫、高橋良輔、芹川忠夫、大野行弘
- Organizer
  第8回日本てんかん学会近畿地方会
- Place of Presentation
  吹田
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pathophysiological alterations ofsynaptic vesicle protein 2A (SV2A) in Groggy rat,a rat model of absence seizure2012
- Author(s)
  Takahiro Okumura 、 Shizuka Ishihara, RyoTerada, Chie Tomita, Ryosuke Kitaya, KentaroTokutome, Tomoya Tanaka, Saki Shimizu,Yoshiko Kawai, Tadao Serikawa, Masashi Sasa,Yukihiro Ohno
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 全般性強直間代発作発現における扁桃核アストロサイト内向き整流性カリウムチャネルKir4.1の関与2012
- Author(s)
  大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 内向き整流性カリウムチャネルKir4.1発現に及ぼす各種抗てんかん薬の影響.2012
- Author(s)
  大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pentylenetetrazol キンドリングによるアストロサイト内向き整流性カリウムチャネル Kir4.1の発現変化.2012
- Author(s)
  向井崇浩、長尾侑紀、小野朝香、阪上嘉久、奥田葵、藤本恵、清水佐紀、大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Episodic ataxia type1(EA1)モデル ADMS ラットの特性評価2012
- Author(s)
  石田紗恵子、坂本雄、西尾賢資、StephanieBaulac、桑村充、大野行弘、滝澤明子、金子周司、芹川忠夫、真下知士
- Organizer
  第59回日本実験動物学会総会, 第46回日本実験動物技術者協会総会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Increases in astrocyticKir4.1 channel expression by antiepileptictreatments2012
- Author(s)
  Yuki Nagao, Takahiro Mukai, Aoi Okuda,Megumi Fujimoto, Asuka Ono, YoshihisaSakagami, Yuya Harada, Saki Shimizu, YoshikoKawai, Yukihiro Ohno
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pentylenetetrazolキンドリングによるアストロサイト内向き整流性カリウムチャネルKir4.1の発現変化.2012
- Author(s)
  大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] てんかんモデルNoda epileptic rat (NER)におけるアストロサイト内向き整流性カリウムチャネルKir4.1の発現解析2011
- Author(s)
  大野行弘
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 抗てんかん薬評価系に求められるパラダイムシフト-ゴールド・スタンダードの意義と限界-2011
- Author(s)
  大野行弘
- Organizer
  第45回日本てんかん学会
- Place of Presentation
  新潟(招待講演)
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pilocarpine誘発側頭葉てんかんモデルにおけるアストロサイトKir4.1チャネルの発現解析2011
- Author(s)
  大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 欠神発作モデルGroggyラットにおけるSV2AおよびSNARE関連タンパクの発現解析2011
- Author(s)
  大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] セロトニン(5-HT)神経系による錐体外路系運動障害の調節メカニズム2011
- Author(s)
  大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 全般性強直-間代発作モデルNoda epileptic ratにおけるアストロサイトKir4. 1チャンネルの病態解析2011
- Author(s)
  長尾侑紀、原田悠耶、奥田葵、藤本恵、芹川忠夫、笹征史、大野行弘
- Organizer
  第7回日本てんかん学会近畿地方会
- Place of Presentation
  京都
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Expressionalanalysis of astroglial Kir4.1 channels in NER, arat model of generalized tonic-clonic seizure2011
- Author(s)
  Yuki Nagao, Yuya Harada, Saki Shimizu, AoiOkuda, Megumi Fujimoto, Tadao Serikawa,Masashi Sasa, Yukihiro Ohno
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Expressional analysis of SV2A and SNARE-related proteins in Groggy rats, a novel absence-like epilepsy model2011
- Author(s)
  Takahiro Okumura, Ryo Terada, Nobumasa Sofue, Shizuka Ishihara, Tadao Serikawa,Masashi Sasa, Yukihiro Ohno
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pilocarpine 誘発側頭葉てんかんモデルにおける内向き整流性カリウム(Kir)チャネルの発現解析2011
- Author(s)
  藤本恵、原田悠耶、長尾侑紀、奥田葵、向井崇浩、小野朝香、阪上嘉久、大野行弘
- Organizer
  第21回臨床精神薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 強直-間代性発作モデルNoda epileptic rat (NER)におけるSV2AおよびSNARE関連タンパクの発現解析2011
- Author(s)
  大野行弘
- Organizer
  第21回臨床精神薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Noda epileptic rat (NER)における扁桃核アストロサイト Kir4.1 チャネルの発現低下2011
- Author(s)
  長尾侑紀、原田悠耶、奥田葵、藤本恵、向井崇浩、小野朝香、阪上嘉久、芹川忠夫、笹征史、大野行弘
- Organizer
  第21回臨床精神薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pilocarpine 誘発側頭葉てんかんモデルにおけるアストロサイト Kir4.1 チャネルの発現解析2011
- Author(s)
  奥田葵、長尾侑紀、原田悠耶、藤本恵、大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 強直-間代性発作モデルNoda epileptic rat (NER)における SV2A およびSNARE 関連タンパクの発現解析2011
- Author(s)
  奥村貴裕、寺田亮、石原靜、北宅良祐、冨田知里、徳留健太郎、田中智也、笹征史、芹川忠夫、大野行弘
- Organizer
  第21回臨床精神薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 強直-間代性発作モデル NER における SV2A および SNARE 関連タンパクの発現解析2011
- Author(s)
  奥村貴裕、寺田亮、石原靜、原田悠耶、北宅良祐、冨田知里、芹川忠夫、笹征史、大野行弘
- Organizer
  日本薬学会第131 年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Noda epileptic rat (NER) における内向き整流性カリウムチャネル Kir4.1 の脳内発現変動2011
- Author(s)
  長尾侑紀、原田悠耶、奥田葵、藤本恵、清水佐紀、芹川忠夫、熊藤健太、笹征史、大野行弘
- Organizer
  日本薬学会第131 年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Noda epileptic rat (NER)における扁桃核アストロサイトKir4.1チャネルの発現低下2011
- Author(s)
  大野行弘
- Organizer
  第21回臨床精神薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 全般性強直-間代発作モデルNoda epileptic ratにおけるアストロサイトKir4.1チャネルの病態解析2011
- Author(s)
  大野行弘
- Organizer
  第7回日本てんかん学会近畿地方会
- Place of Presentation
  京都
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Noda epileptic rat(NER)における扁桃核アストロサイトKir4. 1チャネルの発現低下2011
- Author(s)
  長尾侑紀、原田悠耶、奥田葵、藤本恵、向井崇浩、小野朝香、阪上嘉久、芹川忠夫、笹征史、大野行弘
- Organizer
  第21回臨床精神薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Tremorラットにおける振戦行動の薬理学的解析2011
- Author(s)
  大野
- Organizer
  第57回日本実験動物学会
- Place of Presentation
  京都テルサ(京都市)
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-21300153
[Presentation] 全般性強直-間代発作モデル Noda epileptic ratにおけるアストロサイト Kir4.1 チャンネルの病態解析2011
- Author(s)
  長尾侑紀、原田悠耶、奥田葵、藤本恵、芹川忠夫、笹征史、大野行弘
- Organizer
  第7回日本てんかん学会近畿地方会
- Place of Presentation
  京都
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] てんかんモデル Noda epileptic rat(NER)におけるアストロサイト内向き整流性カリウムチャネルKir4.1 の発現解析2011
- Author(s)
  長尾侑紀、原田悠耶、奥田葵、藤本恵、芹川忠夫、笹征史、大野行弘
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pilocarpine誘発側頭葉てんかんモデルにおける内向き整流性カリウム(Kir)チャネルの発現解析2011
- Author(s)
  大野行弘
- Organizer
  第21回臨床精神薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 欠神発作モデル Groggy ラットにおけるSV2A および SNARE 関連タンパクの発現解析2011
- Author(s)
  奥村貴裕、寺田亮、石原靜、冨田知里、北宅良祐、芹川忠夫、笹征史、大野行弘
- Organizer
  次世代を担う創薬・医療薬理シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 内向き整流性カリウム(Kir)チャネルのてんかん病態における発現解析:ピロカルピン誘発側頭葉てんかんモデルを用いた検討2011
- Author(s)
  小野朝香、原田悠耶、長尾侑紀、藤本恵、奥田葵、向井崇浩、阪上嘉久、河合悦子、大野行弘
- Organizer
  第61回日本薬学会近畿支部大会
- Place of Presentation
  神戸
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 強直-間代性発作モデルNoda epileptic rat(NER)におけるSV2AおよびSNARE関連タンパクの発現解析2011
- Author(s)
  奥村貴裕、寺田亮、石原靜、北宅良祐、冨田知里、徳留健太郎、田中智也、笹征史、芹川忠夫、大野行弘
- Organizer
  第21回臨床精神薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] てんかんモデルNoda epileptic rat(NER)におけるアストロサイト内向き整流性カリウムチャネルKir4. 1の発現解析2011
- Author(s)
  長尾侑紀、原田悠耶、奥田葵、藤本恵、芹川忠夫、笹征史、大野行弘
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] 抗てんかん薬評価系に求められるパラダイムシフト-ゴールド・スタンダードの意義と限界-2011
- Author(s)
  大野行弘
- Organizer
  第45回日本てんかん学会シンポジウム
- Place of Presentation
  新潟
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pharmacological analysis of the hyperthermia-induced-seizure-susceptible (Hiss) rats, a novel rat model of febrile seizure.2010
- Author(s)
  Ohno Y, et al
- Organizer
  The XVIIIth International Workshop on Genetic System in the Rat
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] 欠神発作モデルGroggyラットにおけるシナプス小胞タンパク2A(SV2A)の発現解析2010
- Author(s)
  寺田亮、祖父江伸匡、石原靜、芹川忠夫、笹征史、大野行弘
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Naチャネルにミスセンス変異を有する Hiss ラットにおける海馬 GABA ニューロンの機能異常2010
- Author(s)
  大野行弘、祖父江伸匡、石原靜、真下知士、笹征史、芹川忠夫
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pentylenetetrazole キンドリングによる海馬シナプス小胞タンパク SV2A の発現上昇2010
- Author(s)
  奥村貴裕、石原靜、寺田亮、祖父江伸匡、芹川忠夫、笹征史、大野行弘
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 自発性てんかんモデルNER (Noda epileptic rat)における脳内Fos 発現解析2010
- Author(s)
  原田悠耶、清水佐紀、石原靜、芹川忠夫、熊藤健太、笹征史、大野行弘
- Organizer
  第57回日本実験動物学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Kyoto epileptic rat (KER): A novel rat model of KCNA1 disease2010
- Author(s)
  Satoko Ishida, Tomoji Mashimo, T. Nishio,Yukihiro Ohno, Y. Sakamoto, S. Kaneko, Tadao Serikawa
- Organizer
  The 18th International Workshop on Genetic Systems in the Rat
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 自発性てんかんモデルNER(Noda epileptic rat)における脳内Fos発現解析2010
- Author(s)
  原田悠耶、清水佐紀、石原靜、芹川忠夫、熊藤健太、笹征史、大野行弘
- Organizer
  第57回日本実験動物学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Na_<v1.1>チャネルにミスセンス変異を有するHissラットにおける海馬GABAニューロンの機能異常2010
- Author(s)
  大野行弘, ら
- Organizer
  第20回日本臨床精神神経薬理学会第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Immunohisto chemical studies in Noda epileptic rat(NER): Exploring the seizure foci by brain mapping of c-Fos protein expression2010
- Author(s)
  Harada Y, Shimizu S, Ishihara S, Kumafuji K, Serikawa T, Sasa M, Ohno Y
- Organizer
  The XVIIIth International Workshop on Genetic Systems in the Rat
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Pharmacological analysis of the hyperihermia-induced seizure-susceptible (Hiss) rats, a novel rat model of febrile seizure.2010
- Author(s)
  Ohno Y, et al
- Organizer
  The XVIIIth Internaional Workshop on Genetic System in the Rat
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pentylenetetrazole キンドリングによる海馬歯状回門部 GABA ニューロンにおけるシナプス小胞タンパク SV2A の発現上昇2010
- Author(s)
  奥村貴裕、寺田亮、石原靜、大野行弘
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pharma cological analysis of the hyper the rmia-induced seizure-susceptible(Hiss) rats, a novel rat model of febrile seizure2010
- Author(s)
  Ohno Y, Ishihara S, Sofue N, Mashimo T, Sasa M, Serikawa T
- Organizer
  The XVIIIth International Workshop on Genetic Systems in the Rat
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Tremorラットにおける振戦行動の薬理学的解析2010
- Author(s)
  大野行弘, ら
- Organizer
  第57回日本実験動物学会
- Place of Presentation
  京都市
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-21300153
[Presentation] 強直-間代発作モデルNER ラットにおける内向き整流性カリウムチャネルの発現解析2010
- Author(s)
  原田悠耶、清水佐紀、芹川忠夫、熊藤健太、笹征史、大野行弘
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Na_<v1.1>チャネルにミスセンス変異を有するHissラットにおける海馬GABAニューロンの機能異常2010
- Author(s)
  大野行弘, ら
- Organizer
  第20回日本臨床精神神経薬理学会第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Immunohistochemical studies in Noda epileptic rat (NER): Exploring the seizure foci by brain mapping of c-Fos protein expression2010
- Author(s)
  Yuya Harada, Saki Shimizu, Shizuka Ishihara,Kenta Kumafuji, Tadao Serikawa, Masashi Sasa,Yukihiro Ohno
- Organizer
  The 18th International Workshop on Genetic Systems in the Rat
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] Pharmacological analysis of thehyperthermia-induced seizure-susceptible (Hiss)rats, a novel rat model of febrile seizure2010
- Author(s)
  Yukihiro Ohno, Shizuka Ishihara, NobumasaSofue, Tomoji Mashimo, Masashi Sasa, TadaoSerikawa
- Organizer
  The18th International Workshop on Genetic Systemsin the Rat
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22590092
[Presentation] 熱刺激誘発けいれん感受性ラットの開発:新たな熱性けいれんモデルとして2009
- Author(s)
  真下知士、大守伊織、大内田守、大野行弘、鶴見東志子、三木崇史、若森実、森泰生、芹川忠夫
- Organizer
  Neuro2009(第32回日本神経科学大会)
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Noda Epileptic Rat(NER)における発作時脳内Fos発現の解析2009
- Author(s)
  原田悠耶、清水佐紀、森下真帆、石原靜、熊藤健太、芹川忠夫、笹征史、大野行弘
- Organizer
  第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会・第1回アジアCINP会議合同年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] 熱刺激誘発けいれん感受性ラットの開発:新たな熱性けいれんモデルとして2009
- Author(s)
  真下知士、大守伊織、大内田守、大野行弘、鶴見東志子、三木崇史、若森実、森泰生、芹川忠夫
- Organizer
  Neuro2009(第32 回日本神経科学大会)
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] 電位依存性Na+チャネルScnla変異ラットのけいれん発現感受性評価 : (1)行動薬理学的および脳波学的検討2008
- Author(s)
  大野行弘, ら
- Organizer
  第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Pharmacological analysis for the mechanism of nicotine-induced seizures in rats
- Author(s)
  Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takahiro Okumura, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第48回日本てんかん学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-10-02 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチンによるけいれん発現のメカニズム解析
- Author(s)
  大野行弘、國澤直史、水口裕登、奥村貴裕、徳留健太郎、落合　緑、溝辺雄輔、田村深雪、大高美幸、近持壽郎、高久保佑一、河合悦子、清水佐紀
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Amygdala is the primary causative site for nicotine-induced convulsive seizures
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Yukihiro Ohno
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Enhanced kindling development in synaptic vesicle protein 2A-mutant (Sv2aL174Q) rats
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Naofumi Kunisawa, Saki Shimizu, Ryo Terada, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Pharmacological mechanisms of nicotine-induced convulsive seizures in mice
- Author(s)
  Higor A. Iha, Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Kentaro Tokudome, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Evaluation of seizure susceptibility in the synaptic vesicle protein 2A (SV2A)-mutant rats
- Author(s)
  Kentaro Tokudome, Takahiro Okumura, Tomoji Mashimo, Tadao Serikawa, Naofumi Kunisawa, Saki Shimizu, Masashi Sasa, Yukihiro Ohno
- Organizer
  第48回日本てんかん学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-10-02 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] Analysis of brain regions responsible for nicotine-induced convulsions
- Author(s)
  Naofumi Kunisawa, Saki Shimizu, Yuto Mizuguchi, Takahiro Okumura, Kentaro Tokudome, Miyuki Ohtaka, Hisao Chikamochi, Yuichi Takakubo, Tadao Serikawa, Yukihiro Ohno
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26460111
[Presentation] ニコチンによるけいれん発現の薬理学的解析
- Author(s)
  國澤直史、清水佐紀、水口裕登、奥村貴裕、大高美幸、近持壽郎、高久保佑一、徳留健太郎、芹川忠夫、大野行弘
- Organizer
  第44回日本神経精神薬理学会・第24回日本臨床精神神経薬理学会合同学会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26460111

1. KURAMOTO Takashi (20311409)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. SHIMIZU SAKI (00630815)

# of Collaborated Projects: 2 results

# of Collaborated Products: 58 results
3. SERIKAWA Tadao (30025655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
4. MASHIMO Tomoji (80397554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. KUWAMURA Mitsuru (20244668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KAWAI YOSHIKO (50268299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. Okada Motohiro (10281916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. Ikeda Akio (90212761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
9. 植田勇人 (70244192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 杉浦嘉泰 (00315665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 柿田明美 (80281012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 津田一郎 (10207384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 行木孝夫 (40271712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. 松本理器 (00378754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. 人見健文 (50402904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
16. 菊池隆幸 (40625084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
17. 松橋眞生 (40456885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
18. 下竹昭寛 (80726000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
19. 宇佐美清英 (20829204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
20. 國澤直史 (10858096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
21. 山尾幸広

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
22. 倉智嘉久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 荒川芳輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yukihiro Ohno 大野 行弘

大野 行弘 オオノ ユキヒロ

OHNO Yukihiro 大野 行弘

大野 行宏 オオノ ユキヒロ

Research Projects

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Co-Researchers

Analysis of the mechanisms underlying development of neuropsychiatric diseases with focus on astrocytic potassium buffering functionPrincipal Investigator

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Comprehensive epileptic network analysis in human brain by neuron and glia

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Pathophysiological mechanism of mental disorders associated with dysfunction of synaptic releasePrincipal Investigator

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Mechanisms of tripartite synaptic transmission

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Pathophysiological analysis of epilepsy with focusing on the synaptic release mechanismPrincipal Investigator

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Epilepsy research focusing on the potassium buffering function of brain astrocytesPrincipal Investigator

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Identification of genetic components in a rat model of essential tremor

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Elucidation of the genetic factors in rat epileptic seizures

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[Book] Serotonin receptors as the therapeutic target for central nervous system disorders. In "Serotonin: The Mediator That Spans Evolution" edited by P.M. Pilowsky2019

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[Book] Serotonin：The mediator that spans evolution2019

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[Book] In Vivo Neuropharmacology and Neurophysiology2016

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[Journal Article] Enhanced phase-amplitude coupling of human electrocorticography selectively in the posterior cortical region during rapid eye movement sleep2022

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[Journal Article] Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor2022

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Yukihiro Ohno 大野行弘

大野行弘オオノユキヒロ

OHNO Yukihiro 大野行弘

大野行宏オオノユキヒロ

[Book] Serotonin receptors as the therapeutic target for central nervous system disorders. In "Serotonin: The Mediator That Spans Evolution"　edited by P.M. Pilowsky2019