Sasaki Kan 佐々木幹

… Alternative Names

SASAKI Kan 佐々木幹

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Researcher Number	00444034
Affiliation (Current)	2025: 山形大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2020: 山形大学, 医学部, 客員研究員 2017 – 2019: 山形大学, 医学部, 非常勤講師 2012 – 2016: 山形大学, 医学部, 准教授 2011: 山形大学, 医学部, 講師 2009 – 2010: 山形大学, 医学部, 助教
Review Section/Research Field	Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Keywords	Except Principal Investigator 自然免疫 / 人工関節 / Toll様受容体 / 関節リウマチ / インプラント感染症 / 生体反応 / 感染 / インプラント感染 / 選択的オートファジー / 自然免疫受容体 … More / 人工関節インプラント感染症 / 変形性関節症 / 炎症性滑膜組織 / オートファジー / 人工関節周囲感染 / 薬剤反応性 / 免疫学 / 薬剤抵抗性 / グレード分類 / 疾患活動性 / 炎症性サイトカイン / 炎症性免疫担当細胞 / 獲得免疫 / 制御性免疫 / 薬剤耐性 / 人工関節感染 / Nod様受容体 / マクロファージ / 非感染性骨溶解 / NOD様受容体 / osteolysis / NOD-like receptor / Toll-like receptor / 感染性人工関節 / Total hip arthropasty / Osteolysis / Aseptic loosening / NLR / TLR / 人工股関節の弛み / 感染症 / シグナル伝達 Less

Innate immune receptor and alternative autophagy in pathogenesis of prosthetic joint infection
- Principal Investigator
  
  Takagi Michiaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Yamagata University
The role of innate immunology in the patients with early rheumatoid arthritis and resistant-anti rheumatic drugs
- Principal Investigator
  
  Takakubo Yuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Innate immunity reaction in marcophage for periprosthetic joint infection
- Principal Investigator
  
  Takagi Michiaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Analyses of innate immune sensors, TLR and NLR, in periprosthetic infection.
- Principal Investigator
  
  TAKAGI Michiaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University
Analysis on mechanisms of Toll-like receptors in infected totally hip joint replacements
- Principal Investigator
  
  TAKAGI Michiaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamagata University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] 変形性関節症（股関節）の手術療法　～骨切り術から人工股関節置換術まで～2017
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰
- Total Pages
  9
- Publisher
  Pharma Medica
- Data Source
  KAKENHI-PROJECT-17K10995
[Book] 変形性関節症（股関節）の手術療法　～骨切り術から人工股関節置換術まで～2017
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰
- Total Pages
  9
- Publisher
  Pharma Medica
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] Rapid disappearing of gouty tophi of foot due to reducing urate pool by resection of huge gouty tophi of opposite foot in the patient with hyperuricemia; a case of report.2019
- Author(s)
  Takakubo Y, Imamura Y, Tezuka H, Okada S, Naganuma Y, Ito J, Sugawara M, Yang S, Oki H, Sasaki A, Sasaki K, Takagi M
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 4 Issue: 1 Pages: 1-6
- DOI
  10.1080/24725625.2019.1680135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02917, KAKENHI-PROJECT-17K10995
[Journal Article] Assessing an alpha-defensin lateral flow device for diagnosing septic arthritis: reporting on a false-negative case and a false-positive case.2019
- Author(s)
  2.Narita A, Suzuki A, Nakajima T, Takakubo Y, Ito J, Sasaki A, Takagi M
- Journal Title
  
  Modern Rheumatology Case Reports.
  
  Volume: 4 Issue: 1 Pages: 156-160
- DOI
  10.1080/24725625.2019.1683134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10995, KAKENHI-PROJECT-18H02917
[Journal Article] Disassembly of bilateral bipolar heads within 10 years after hip hemiarthroplasties for avascular necrosis of femoral heads: a case report.2019
- Author(s)
  Ito J, Takakubo Y, Monma R, Oki H, Sasaki K, Takagi M
- Journal Title
  
  Modern Rheumatology Case Reports.
  
  Volume: 4 Issue: 1 Pages: 147-151
- DOI
  10.1080/24725625.2019.1662596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02917, KAKENHI-PROJECT-17K10995
[Journal Article] Distribution of podoplanin in synovial tissues in rheumatoid arthritis patients using biologic or conventional disease-modifying anti-rheumatic drugs.2017
- Author(s)
  Takakubo Y, Oki H, Naganuma Y, Sasaki K, Sasaki A, Tamaki Y, Suran Y, Konta T, Takagi M
- Journal Title
  
  Curr Rheumatol Rev
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] 精神疾患を有する患者に対する人工股関節全置換術の周術期合併症と短期成績2016
- Author(s)
  竹内隆二, 佐々木幹, 高窪祐弥, 伊藤重治, 平山朋幸, 大木弘治, 高木理彰
- Journal Title
  
  Hip joint
  
  Volume: ４２ Pages: 944-946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes.2016
- Author(s)
  Naganuma Y, Takakubo Y, Takagi M, et al
- Journal Title
  
  Journal of Biomedical Material and Research A
  
  Volume: 104 Issue: 2 Pages: 435-444
- DOI
  10.1002/jbm.a.35581
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] 過去11年間の人工股関節手術件数の推移 -当院と関連病院の傾向と特徴-2016
- Author(s)
  高窪祐弥, 伊藤重治, 佐々木幹, 平山朋幸, 大木弘治, 門馬亮介, 玉木康信, 川路博之, 小林真司, 石井政次, 高木理彰
- Journal Title
  
  Hip joint
  
  Volume: 42 Pages: 912-914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] トシリズマブ使用関節リウマチ患者における人工関節手術の検討2016
- Author(s)
  高窪祐弥, 大石隆太, 伊藤重治, 長沼靖, 梁秀蘭, 佐々木明子, 佐々木幹, 大類広, 高木理彰
- Journal Title
  
  日人工関節会誌
  
  Volume: 46 Pages: 633-634
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] PJIの病理組織学的検討.2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Journal Title
  
  関節外科
  
  Volume: 34 Pages: 35-41
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] 過去10年間の人工関節手術件数の推移-当院と関連病院の傾向と特徴-2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Journal Title
  
  日本人工関節会誌
  
  Volume: 45 Pages: 773-774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10459
[Journal Article] 大径骨頭金属対金属摺動面人工股関節の中間成績2014
- Author(s)
  平山朋幸, 佐々木幹, 高窪祐弥, 高木理彰
- Journal Title
  
  日本人工関節学会誌
  
  Volume: 44 Pages: 389-390
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] Inflammatory immune cell responses and Toll-like receptor expression in synovial tissues in rheumatoid arthritis patients treated with biologics or DMARDs.2013
- Author(s)
  Takakubo Y, Tamaki Y, Hirayama T, Iwazaki K, Sasaki K, Sasaki A, Takakubo N, Konttinen YT, Takagi M
- Journal Title
  
  Clin Rheumatol
  
  Volume: 32 Pages: 853-861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] 当院における不安定性骨盤輪損傷の治療成績2012
- Author(s)
  佐々木幹、高木理彰、高窪祐弥、大木弘治、小林真司
- Journal Title
  
  Hip Joint
  
  Volume: 38 Pages: 668-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] リウマチ性疾患のジャクー関節症における病理組織学的検討.2012
- Author(s)
  高窪祐弥、佐々木明子、高木理彰
- Journal Title
  
  関節の外科
  
  Volume: 39 Pages: 19-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] THAの合併症対策. 骨溶解･弛み. 病態と対策. 基礎的視点から.2012
- Author(s)
  高木理彰、佐々木幹
- Journal Title
  
  関節外科
  
  Volume: 31 Pages: 56-63
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] Minocycline-induced periarticular black bone in patients with inflamed joints who have undergone total arthroplasties; five case report and review of the literature.2012
- Author(s)
  Yang S, Takakubo Y, Sasaki K, Takagi M, et al
- Journal Title
  
  Clin Orthop Surg
  
  Volume: 4 Issue: 3 Pages: 181-187
- DOI
  10.4055/cios.2012.4.3.181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] 山形大学式（YU）人工股関節システムにおける長期成績の推測は可能か？2012
- Author(s)
  玉木康信、石井政次、川路博之、神囿純一、佐々木幹、大楽勝之、高木理彰
- Journal Title
  
  Hip Joint
  
  Volume: 38 Pages: 270-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592252
[Journal Article] Postoperative prophylactic effect of fondaparinux for prevention of deep venous thrombosis after cemented total hip arthroplasty. A comparative study2011
- Author(s)
  Tamaki Y, Sasaki K, Takagi M, et al.
- Journal Title
  
  Modern Rheum
  
  Volume: (Epub ahead of print) Issue: 2 Pages: 216-222
- DOI
  10.1007/s10165-011-0496-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591929
[Journal Article] 凍結乾燥硫酸アミカシン含有骨セメントの性状に関する検討2010
- Author(s)
  佐々木幹
- Journal Title
  
  日本人工関節学会誌
  
  Volume: 40 Pages: 232-233
- Data Source
  KAKENHI-PROJECT-21591929
[Journal Article] Antibiotics impregnated cement spacers in the first step of two-stage revision for infected totally replaced hip joints
- Author(s)
  Sasaki K, Takagi M, et al.
- Journal Title
  
  J Orthop Sci
  
  Volume: 14 Pages: 704-710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591929
[Journal Article] Postoperative prophylactic effect of fondaparinux for prevention of deep venous thrombosis after cemented total hip arthroplasty
- Author(s)
  Tamaki Y, Sasaki K, Takagi M, et al.
- Journal Title
  
  A comparative study. Modern Rheum
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591929
[Journal Article] Toll-like receptors and their adaptors are regulated in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles
- Author(s)
  Hirayama T, Tamaki Y, Takakubo Y, Iwazaki K, Sasaki K, Goodman S, Konttinen YT, Takagi M
- Journal Title
  
  J Orthop Res
  
  Volume: 29 Pages: 984-992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591929
[Journal Article] Cement removal and bone bed preparation of the femoral medullary canal assisted by flexible endoscope in total hip revision arthroplasty
- Author(s)
  Takagi M, Tamaki Y, Sasaki K, Takakubo Y, et al.
- Journal Title
  
  J Orthop Sci
  
  Volume: 14 Pages: 719-726
- NAID
  10027402220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591929
[Journal Article] 人工関節感染症と生体反応
- Author(s)
  高木理彰, 玉木康信, 高窪祐弥, 平山朋幸, 佐々木幹
- Journal Title
  
  Monthly Book Orthopedics
  
  Volume: 24
- Data Source
  KAKENHI-PROJECT-21591929
[Presentation] Distrbution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019
- Author(s)
  1.Takakubo Y, Oki H, Yang S, Sasaki A, Sasaki K, Naganuma Y, KatoY, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry.2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A, Oki H, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Rehabilitation of the salvege arthrodesis with bone auto- and allografts for failed total ankle arthroplasties in the patient with rheumatoid arthritis.2019
- Author(s)
  Takakubo Y, Narita A, Takano M, Suzuki Y, Sasaki K, Ito J, Sagae H, Kanauchi Y, Kobayashi S, Takagi M
- Organizer
  56th Annual Meeting of Japanese Association of Rehabilitation Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Rehabilitation of the salvege arthrodesis with bone auto- and allografts for failed total ankle arthroplasties in the patient with rheumatoid arthritis2019
- Author(s)
  Takakubo Y, Narita A, Takano M, Suzuki Y, Sasaki K**, Ito J, Sagae H**, Kanauchi Y**, Kobayashi S**, Takagi M
- Organizer
  56th Annual Meeting of Japanese Association of Rehabilitation Medicine
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Distribution of immune-suppressive cells and Toll-like receptors in synovial tissues in the patients with rheumatoid arthritis which were treated by anti-TNF agents2019
- Author(s)
  Takakubo Y, Yang S, Suzuki Y, Oki H, Naganuma Y**, Sasaki A**, Sasaki K**, Orui H**, Takagi M
- Organizer
  The 63rd Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry.2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A**, Oki H**, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Radiographic joint destruction in the patients with rheumatoid arthritis who have withdrawn, spaced or continued biologics after reaching remission from local biologics registry2019
- Author(s)
  Nagai J, Takakubo Y, Yang S, Suzuki Y, Sasaki A**, Oki H**, Naganuma Y**, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Comparison of clinical features between subtrochanteric and diaphyseal atypical femoral fractures in our super-aging area.2019
- Author(s)
  Miyaji T, Takakubo Y, Ota D, Shibuya J, Oki H, Ito J, Sasaki K**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] The trend of revision total hip arthroplasties in super-aging area in last fourteen years.2019
- Author(s)
  Takakubo Y, Ito J, Oki H**, Momma R, Sasaki K**, Kawaji H**, Ishi M**, Takagi M
- Organizer
  The 92nd Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Distrbution of Toll-like receptors expressing immune-cells in rheumatoid synovial tissues of the patients who received CTLA4-Ig agent.2019
- Author(s)
  Takakubo Y, Oki H, Yang S, Sasaki A, Sasaki K, Naganuma Y, KatoY, Takagi M
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] The relationship between sarcopenia and cognitive function in the patients with transaortic valve implantation.2019
- Author(s)
  Sasaki K, Murakawa M, Takakubo Y, Takagi M, Kouzuki M
- Organizer
  13th International Society of Physical and Rehabilitation Medicine World Congress,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02917
[Presentation] Foot and ankle surgeries for the patients with rheumatoid arthritis in BIO-era.2018
- Author(s)
  Takakubo Y, Oki H, Sasaki K
- Organizer
  62th Annual Meeting of Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] The Value of Serum Interleukin-6 Before First Biologis Are Predicted to Clinical Response in The Patients of Rheumatoid Arthritis One Year After The Treatment.2018
- Author(s)
  Takakubo Y, Oki H, Sasaki K, et al:
- Organizer
  ORS 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Tumor necrosis factor inhibitors influence the apoptosis of inflammatory cells in rheumatoid synovial tissues.2018
- Author(s)
  Takakubo Y, Oki H, Sasaki K
- Organizer
  62th Annual Meeting of Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-17K10995
[Presentation] Trend of total hip arthroplasties in the super-aging area in Northern Japan.2017
- Author(s)
  Takakubo Y, Sasaki K, Ito J, Oki H, Honma R, Kawaji H, Ishii M, Takagi M
- Organizer
  ISTA 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Postoperative rehabilitation of atypical femoral fractures in patients with rheumatic diseases2017
- Author(s)
  Takakubo Y, Sasaki K, Narita Atsushi, Narita Aya, Kanauti Y, Yamakawa J, Sugawara M, Kobayashi S, Hanaka N, Takagi M
- Organizer
  The 54th Annual meeting of the Japanese association of rhehabilitation medicine
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] The incidence of atypical femoral fractures in patients with rheumatic disease in our prefectural area of north Japan in the suger-aging society: YamaCAFe study2017
- Author(s)
  Takakubo Y, Ohta D, Okuda S, Ito J, Oki H, Naganuma Y, Sasaki K, Ishii M, Takagi M
- Organizer
  The 90th Annual Meeting of the Japanese Orthopaedic Association
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Is increasing the trend of primary total hip arthroplasties for the patients with osteoarthritis, but decreasing the rate of female in super-aging area of Japan in last twelve years?2017
- Author(s)
  Takakubo Y, Sasaki K, Oki H, Naganuma Y, Narita A, Hirayama T, Tamaki Y, Takagi Y
- Organizer
  EULAR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] The effect of anti-TNF inhibitors on innate immune system in synovial tissues in rheumatoid arthritis patients2016
- Author(s)
  Takakubo Y, Oki H, Yang S, Hanaka N, Sasaki A, Ito J, L Xing, Sasaki K, Takagi M
- Organizer
  2016 International Comibned Meeting of Orthopaedic Research Societies
- Place of Presentation
  Convention center (Xi’an, Chaina)
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] The relationship between reduction pattern and sliding distance in AO/OTA 31-A2/A3 trochanteric fractures in the elderly2016
- Author(s)
  Ito J, Sasaki K, Takakubo Y, Momma R, Takagi M
- Organizer
  The 9th Clare Valley Bone Meeting, Clare Valley
- Place of Presentation
  Clare Convention Centre　（Clare Valley, Australia）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Outcome of rotational acetabular osteotomy for dysplastic follow up for minimum 15 years2016
- Author(s)
  Sasaki K, Ida H, Ishii M, Kawaji H, Takakubo Y, Ito J, Monma R, Takagi M
- Organizer
  The 9th Clare Valley Bone Meeting, Clare Valley
- Place of Presentation
  Clare Convention Centre　（Clare Valley, Australia）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] A platelet aggregation-inducing factor podoplanin is highly expressed metastatic legions of osteosarcoma2016
- Author(s)
  Oki H, Yang S, Hanaka N, Sasaki A, Ito J, L Xing, Sasaki K, Takagi M
- Organizer
  2016 International Comibned Meeting of Orthopaedic Research Societies
- Place of Presentation
  Convention center (Xi’an, Chaina)
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Trend of atypical femoral fractures in rheumatic patients in the highly super aging area of North Japan2016
- Author(s)
  Takakubo Y, Ota D, Naganuma Y, Oki H, Narita A, Ito J, Sasaki K, Takagi M
- Organizer
  European League Against Rheumatism 2016
- Place of Presentation
  Excell center (London, UK)
- Year and Date
  2016-06-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Normative data of key and pulp pinches to grip strength in healthy twenties2016
- Author(s)
  Hanaka N, Sasaki A, Ito J, L Xing, Sasaki K, Takagi M
- Organizer
  2016 International Comibned Meeting of Orthopaedic Research Societies
- Place of Presentation
  Convention center (Xi’an, Chaina)
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Expression of Toll-like receptors and distribution of immune-cells in rheumatoid synovial tissues of the patients treated by Abatacept2016
- Author(s)
  Takakubo Y, Naganuma Y, Oki H, Yang S, Sasaki K, Takagi M
- Organizer
  European League Against Rheumatism 2016
- Place of Presentation
  Excell center (London, UK)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 過去11年間の人工股関節手術件数の推移-当院と関連病院の傾向と特徴-2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Organizer
  第42回日本股関節学会学術集会
- Place of Presentation
  グランフロント大阪, 大阪市, 大阪
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 当科における人工股関節感染予防の取り組みと感染率の変化2015
- Author(s)
  佐々木幹, 高窪祐弥, 高木理彰ほか
- Organizer
  第88回日本整形外科学会学術総会
- Place of Presentation
  神戸ポートピアホテル, 神戸市, 兵庫
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 過去11年間の人工股関節手術件数の推移 -当院と関連病院の傾向と特徴-2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Organizer
  第42回日本股関節学会学術集会
- Place of Presentation
  グランフロント大阪, 大阪市, 大阪
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Danage-associated molecular patterns(damps) of toll-like receptors in aseptic loosened total hip arthroplasty.2015
- Author(s)
  Takakubo Y, Sasaki K, Takagi M, et al
- Organizer
  ORS annual meeting
- Place of Presentation
  MGM Grand Hotel, Las Vegas, NV, USA
- Year and Date
  2015-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] Immunohistochemical localization and cellular reaction of Tlr2 and Nlrp3 cascades in aseptic loosening of totally hip joints.2015
- Author(s)
  Takakubo Y, Sasaki K, Takagi M, et al
- Organizer
  ORS annual meeting
- Place of Presentation
  MGM Grand Hotel, Las Vegas, NV, USA
- Year and Date
  2015-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 無菌性弛緩人工股関節の病態におけるNLPR3の関与2015
- Author(s)
  高窪祐弥, 佐々木幹, 高木理彰ほか
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場, 富山市, 富山
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K10459
[Presentation] 人工股関節インプラント感染症におけるToll-like receptor(TLR)を介した宿主生体反応.2014
- Author(s)
  玉木康信, 佐々木幹, 高窪祐弥, 平山朋幸, 長沼靖, 川路博之, 石井政次, 高木理彰
- Organizer
  第37回日本骨・関節感染症学会.
- Place of Presentation
  京王プラザホテル, 東京
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] RAK2 maintained increased cellular reactivity of macrophages after phagocytosis lipoteichoic acid –coated titanium particles2013
- Author(s)
  Naganuma Y, Hirayama T, Tamaki Y, Takakubo Y, Sasaki K, Takagi M
- Organizer
  59th Orthopaedic Reserch Society
- Place of Presentation
  Henry B Gozalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Irak2 maintained increased cellular reactivity of macrophages after phagocytosis lipoteichoic acid- coated titanium particles.2013
- Author(s)
  Naganuma Y, Takakubo Y, Sasaki K, Takagi M, et al
- Organizer
  59th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Henry B. Gonzalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Periprosthetic osteolysis around total hip implantspast, present and future2013
- Author(s)
  Takagi M, Sasaki K, Takakubo Y, Tamaki Y, Hirayama T, Naganuma Y, Kawaji H, Ishii M
- Organizer
  The 57th Annual Fall Congress,Korean Orthopaedic Association
- Place of Presentation
  Grand Hilton Hotel, Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] High mobility group box-1 (HMGB-1) in aseptic and septic loose total hip arthroplasty2013
- Author(s)
  Tamaki Y, Takakubo Y, Hirayama T, Sasaki K, Naganuma Y, Goodman SB, Konttinen YT, Takagi M
- Organizer
  59th Orthopaedic Reserch Society
- Place of Presentation
  Henry B Gozalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Expression of toll-like receptors (TLRs) and cathepsin K in periptrosthetic aseptic osteolysis of total hip arthloplasty.2013
- Author(s)
  Tamaki Y, Takakubo, Sasaki K, Takagi M, et al
- Organizer
  59th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Henry B. Gonzalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] High Mobility Group Box-1 (HMGB-1) in Aseptic and Septic Loose Total Hip Arthroplasty2013
- Author(s)
  Tamaki Y, Takakubo Y, Sasaki K, Goodman SB, Konttinen YT, Takagi M, et al
- Organizer
  59th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Henry B. Gonzalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Expression of toll-like receptors (TLRs) and cathepsin K in periprosthetic aseptic osteolysis of total hip arthroplasty.2013
- Author(s)
  Tamaki Y, Takakubo Y, Hirayama T, Naganuma Y, Sasaki K, Goodman SB, Konttinen YT, Takagi M
- Organizer
  59th Orthopaedic Reserch Society
- Place of Presentation
  Henry B Gozalez Convention Center, San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Innate immune sensors enhanced macrophagic reaction after phagocytosis of wear debris in so called “aseptic ” condition2012
- Author(s)
  Naganuma Y, Takakubo Y, Sasaki K, Takagi M, et al
- Organizer
  20th European Orthopaedic Research Society
- Place of Presentation
  ACTA Building, VU University, Amsterdam, Nederland
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 生物学的製剤（BIO）投与関節リウマチ（RA）滑膜表層組織におけるToll-like receptor（TLR）陽性細胞の検討2012
- Author(s)
  高窪祐弥、玉木康信、梁秀蘭、大木弘治、平山朋幸、長沼靖、佐々木明子、佐々木幹、大類広、高木理彰
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Supression of TLR4 and IRAK-1, 4 in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles2012
- Author(s)
  Takagi M, Takakubo Y, Sasaki K, Konttinen YT, et al
- Organizer
  20th European Orthopaedic Research Society
- Place of Presentation
  ACTA Building, VU University, Amsterdam, Nederland
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Analysis of Toll-like receptor mediating signal pathway in periprosthetic infection2012
- Author(s)
  Tamaki Y, Takakubo Y, Sasaki K, Konttinen YT, Goodman SB, Takagi M, et al
- Organizer
  20th European Orthopaedic Research Society
- Place of Presentation
  ACTA Building, VU University, Amsterdam, Nederland
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 非感染性弛緩人工股関節周囲組織におけるhigh mobility group box-1（HMGB-1）発現に関する検討2012
- Author(s)
  玉木康信、高窪祐弥、平山朋幸、長沼靖、佐々木幹、川路博之、石井政次、高木理彰
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 生物学的製剤投与中の関節リウマチ患者における人工股関節全置換術後の検討2012
- Author(s)
  高窪祐弥、佐々木幹、玉木康信、大木弘治、長沼靖、川路博之、小林真司、石井政次、高木理彰
- Organizer
  第39回日本股関節学会学術集会
- Place of Presentation
  新潟コンベンションセンター, 新潟
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Lipopolysaccharide（LPS）付着チタン粒子刺激骨髄マクロファージにおけるtoll-like receptors（TLRs）とアダプター分子の発現2012
- Author(s)
  平山朋幸、高木理彰、玉木康信、高窪祐弥、長沼靖、佐々木幹
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 感染性，非感染性弛緩人工股関節周囲組織におけるToll-like receptor（TLR）シグナル伝達系の解析2012
- Author(s)
  玉木康信、高窪祐弥、平山朋幸、佐々木幹、佐々木明子、梁秀蘭、長沼靖、石井政次、高木理彰
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] グラム陽性球菌由来病原体関連分子パターンによる免疫応答修飾2012
- Author(s)
  長沼靖、平山朋幸、玉木康信、高窪祐弥、佐々木幹、高木理彰
- Organizer
  第56回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] リポテイコ酸付着チタン摩耗粉貪食によるマクロファージ反応性の亢進2012
- Author(s)
  長沼靖、平山朋幸、玉木康信、高窪祐弥、佐々木幹、高木理彰
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] The concentration of serum interleukin-6 before biologic treatment are related to clinical response in the patients of rheumatoid arthritis.
- Author(s)
  Takakubo Y, Ohki H, Yang S, Sasaki A, Sasaki K, Hirayama T,Tamaki Y,Naganuma Y,Orui H, Takagi M
- Organizer
  European League Against Rheumatism 2014
- Place of Presentation
  Palais des Congres, Paris, France
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] リポテイコ酸付着チタン摩耗粉貪食マクロファージの免疫応答修飾におけるTLR2及びNLRP3反応系の関与
- Author(s)
  長沼靖、平山朋幸、大木弘治、梁秀蘭、丸山真博、玉木康信、高窪祐弥、佐々木幹、高木理彰
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル, 鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 異物肉芽腫反応とリウマチ性関節炎におけるマクロファージの役割.
- Author(s)
  玉木康信, Jukka Pajarinen, 高窪祐弥, 梁秀蘭, 長沼靖, 平山朋幸, 大木弘治, 佐々木幹, 川路博之, 石井政次, Hekki Valleala, Yrjo T. Konttinen, Stuart B. Goodman, 高木理彰
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル, 鹿児島
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Analyses on immunohistochemical localization of TLR2 and NLRP3 in aseptic periprosthetic tissues around loose hip joints and their response to foreign body particles.
- Author(s)
  Naganuma Y, Hirayama T, Tamaki Y, Takakubo Y, Oki H, Yang S, Sasaki K, Kawaji H, Ishii M, Takagi M
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] リポテイコ酸刺激マクロファージにおけるTLR2およびTLR6の発現様式
- Author(s)
  長沼靖、大木弘治、梁秀蘭、平山朋幸、玉木康信、高窪祐弥、結城北斗、佐々木明子、佐々木幹、高木理彰
- Organizer
  第58回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Acetabular reconstruction of extensive bone defect with reinforce device in revision total hip arthroplasty.
- Author(s)
  Ishii M, Takagi M, Kawaji H, Tamaki Y, Sasaki K
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Total Joint Arthroplasties for Rheumatoid Arthritis in Era of Biologics.
- Author(s)
  Takakubo Y, Sasaki K, Narita A, Oki H, Hirayama T, Suzuki A, TamakiY, Togashi E, Kawaji H, Fukushima S, Ishii M, Takagi M
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] The outcome of treatment for infected total hip.
- Author(s)
  Sasaki K, Ishii M, Kawaji H, Takakubo Y, Tamakai Y, Hirayama T, Takagi M
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Is podoplanin a new candidate of inflammatory markers for rheumatoid arthritis?
- Author(s)
  Takakubo Y, Ohki H, Yang S, Sasaki A, Sasaki K, Hirayama T,Tamaki Y,Naganuma Y, Yukinari Kato, Takagi M
- Organizer
  European League Against Rheumatism 2014
- Place of Presentation
  Palais des Congres, Paris, France
- Year and Date
  2014-06-11 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] 弛緩人工股関節異物肉芽腫組織におけるTLR2、NLRP-3シグナル伝達機構に関する免疫組織化学的検討
- Author(s)
  長沼靖、高窪祐弥、佐々木幹、佐々木明子、玉木康信、成田淳、梁秀蘭、大木弘治、結城北斗、高木理彰
- Organizer
  第58回日本リウマチ学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Immunohistochemical localization and cellular reaction of TLR2 and NLRP3 cascades in aseptic loosening of totally replaced hip joints.
- Author(s)
  Naganuma Y, Hirayama T, Ooki H, Liu X, Yang S, Tamaki Y, Takakubo Y, Sasaki K, Takagi M
- Organizer
  Orthopaedic Research Society annual meeting
- Place of Presentation
  MGM Grand Hotel, Las Vegas, Nevada USA
- Year and Date
  2015-03-28 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-24592252
[Presentation] Mid-term clinical results of PINNACLE metal on metal total hip arthroplasty
- Author(s)
  Hirayama T, Sasaki K, Takakubo Y, Ito J, Takagi M
- Organizer
  ISTA 2014 Kyoto Scientific
- Place of Presentation
  Hotel Okura Kyoto, Kyoto, Japan
- Year and Date
  2014-09-24 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24592252

1. TAKAGI Michiaki (40241707)

# of Collaborated Projects: 5 results

# of Collaborated Products: 83 results
2. Takakubo Yuya (80431641)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 長沼靖 (10463811)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 大木弘治 (20463812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. ASANO Tamon (10344805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. GOTO Kaoru (30234975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YAMAKAWA Mitsunori (20183676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAKUBO Yuya (80431461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 109 results
9. 伊藤重治 (50764122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

Sasaki Kan 佐々木 幹

SASAKI Kan 佐々木 幹

Research Projects

Research Products

Co-Researchers

Innate immune receptor and alternative autophagy in pathogenesis of prosthetic joint infection

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

The role of innate immunology in the patients with early rheumatoid arthritis and resistant-anti rheumatic drugs

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Innate immunity reaction in marcophage for periprosthetic joint infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of innate immune sensors, TLR and NLR, in periprosthetic infection.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on mechanisms of Toll-like receptors in infected totally hip joint replacements

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 変形性関節症（股関節）の手術療法 ～骨切り術から人工股関節置換術まで～2017

Author(s)

Total Pages

Publisher

Data Source

[Book] 変形性関節症（股関節）の手術療法 ～骨切り術から人工股関節置換術まで～2017

Author(s)

Total Pages

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Data Source

[Journal Article] Rapid disappearing of gouty tophi of foot due to reducing urate pool by resection of huge gouty tophi of opposite foot in the patient with hyperuricemia; a case of report.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Assessing an alpha-defensin lateral flow device for diagnosing septic arthritis: reporting on a false-negative case and a false-positive case.2019

Author(s)

Journal Title

DOI

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[Journal Article] Disassembly of bilateral bipolar heads within 10 years after hip hemiarthroplasties for avascular necrosis of femoral heads: a case report.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distribution of podoplanin in synovial tissues in rheumatoid arthritis patients using biologic or conventional disease-modifying anti-rheumatic drugs.2017

Author(s)

Journal Title

Data Source

[Journal Article] 精神疾患を有する患者に対する人工股関節全置換術の周術期合併症と短期成績2016

Author(s)

Journal Title

Data Source

[Journal Article] Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 過去11年間の人工股関節手術件数の推移 -当院と関連病院の傾向と特徴-2016

Author(s)

Journal Title

Data Source

[Journal Article] トシリズマブ使用関節リウマチ患者における人工関節手術の検討2016

Author(s)

Journal Title

Sasaki Kan 佐々木幹

SASAKI Kan 佐々木幹

[Book] 変形性関節症（股関節）の手術療法　～骨切り術から人工股関節置換術まで～2017

[Book] 変形性関節症（股関節）の手術療法　～骨切り術から人工股関節置換術まで～2017

[Journal Article] 大径骨頭金属対金属摺動面人工股関節の中間成績2014