Miyahara Hiroaki 宮原弘明

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MIYAHARA HIROAKI 宮原弘明

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Researcher Number	00457615
Other IDs	https://orcid.org/0000-0003-0723-0047
Affiliation (Current)	2025: 愛知医科大学, 加齢医科学研究所, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 愛知医科大学, 加齢医科学研究所, 准教授 2020 – 2021: 愛知医科大学, 付置研究所, 准教授 2018 – 2020: 愛知医科大学, 付置研究所, 講師 2017: 大分大学, 医学部, 助教 2012 – 2016: 大分大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 51030:Pathophysiologic neuroscience-related / Embryonic/Neonatal medicine
Keywords	Principal Investigator 脳卒中様エピソード / MELAS / ミトコンドリア病 / オートファジー / 遺伝子変異率 / ミトコンドリア / ヘテロプラスミー / 線維芽細胞 / ミトコンドリア活性 / 変異ミトコンドリア … More / ミトファジー / Leigh脳症 / mTOR / 細胞培養 / ウェスタンブロット / 結節性硬化症 … More Except Principal Investigator i-GONAD / 知的障害 / 多相遺伝 / モデルマウス / てんかん / 伝播 / 凝集 / 剖検脳組織 / 蛋白質伝播 / ニューロフィラメント / 交感神経節 / 三次元解析 / 組織透明化 / 神経病理学 / タウ / アルファシヌクレイン / 三次元イメージング / 組織透明化技術 / 神経変性疾患 / パーキンソン病 / 栄養 / 肝臓 / 新生児 / 飢餓 / オートファジー Less

Investigation of pleiotropic etiology of epilepsy by generating rapid and precise gene-edited mouse
- Principal Investigator
  
  林深
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Institute for Developmental Research Aichi Developmental Disability Center
Mitochondria function analysis using autopsied brain samples of MELASPrincipal Investigator
- Principal Investigator
  
  宮原弘明
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aichi Medical University
Mechanisms of lesion formation in Parkinson's disease: an analysis using tissue clearing and 3D observation
- Principal Investigator
  
  Shimizu Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Niigata University
The role of autophagy in starvation response immediately after birth
- Principal Investigator
  
  Sekiguchi Kazuhito
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Oita University
Evaluation of mitophagy activity in patients with Leigh encephalopathyPrincipal Investigator
- Principal Investigator
  
  Miyahara Hiroaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Aichi Medical University
  Oita University
The therapeutic research using Autophagy in Tuberous sclerosis complexPrincipal Investigator
- Principal Investigator
  
  MIYAHARA HIROAKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Oita University

All 2023 2019 2013

All Journal Article

[Journal Article] Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation2023
- Author(s)
  Hiroaki Miyahara
- Journal Title
  
  Brain Pathology
  
  Volume: 33 Issue: 6
- DOI
  10.1111/bpa.13199
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08196
[Journal Article] Autopsied case with MERRF/MELAS overlap syndrome accompanied by stroke‐like episodes localized to the precentral gyrus2019
- Author(s)
  Miyahara Hiroaki、Matsumoto Shinjiro、Mokuno Kenji、Dei Rika、Akagi Akio、Mimuro Maya、Iwasaki Yasushi、Yoshida Mari
- Journal Title
  
  Neuropathology
  
  Volume: 印刷中 Issue: 3 Pages: 135-143
- DOI
  10.1111/neup.12551
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09597, KAKENHI-PROJECT-16K08020
[Journal Article] Suppressed Expression of Autophagosomal Protein LC3 in Cortical Tubers of2013
- Author(s)
  Miyahara H, Natsumeda M, Shiga A, Aoki H, Toyoshima Y, Zheng Y, Takeuchi R,
- Journal Title
  
  Brain Pathol.
  
  Volume: 23 Issue: 3 Pages: 254-262
- DOI
  10.1111/j.1750-3639.2012.00634.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791074, KAKENHI-PROJECT-25250008, KAKENHI-PROJECT-25462247, KAKENHI-PROJECT-25640027

1. 井原健二 (80294932)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Sekiguchi Kazuhito (40437926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 吉田眞理 (60288545)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 花田俊勝 (10363350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Shimizu Hiroshi (40608767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 柿田明美 (80281012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岩崎靖 (60378172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 井上真紀 (20726913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 林深 (50596244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Miyahara Hiroaki 宮原 弘明

MIYAHARA HIROAKI 宮原 弘明

Research Projects

Research Products

Co-Researchers

Investigation of pleiotropic etiology of epilepsy by generating rapid and precise gene-edited mouse

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mitochondria function analysis using autopsied brain samples of MELASPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of lesion formation in Parkinson's disease: an analysis using tissue clearing and 3D observation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of autophagy in starvation response immediately after birth

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of mitophagy activity in patients with Leigh encephalopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The therapeutic research using Autophagy in Tuberous sclerosis complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autopsied case with MERRF/MELAS overlap syndrome accompanied by stroke‐like episodes localized to the precentral gyrus2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppressed Expression of Autophagosomal Protein LC3 in Cortical Tubers of2013

Author(s)

Journal Title

DOI

Data Source

Miyahara Hiroaki 宮原弘明

MIYAHARA HIROAKI 宮原弘明