YAGI Takanobu 八木高伸

Researcher Number	00468852
Other IDs	https://orcid.org/0000-0003-0951-3876
Affiliation (Current)	2024: 早稲田大学, 理工学術院, 主任研究員(研究院准教授)
Affiliation (based on the past Project Information) *help	2018 – 2024: 早稲田大学, 理工学術院, 主任研究員(研究院准教授) 2017: 早稲田大学, 理工学術院, 客員主任研究員(研究院客員准教授) 2017: 早稲田大学, 理工学術院, 研究院准教授 2016: 早稲田大学, 理工学術院, 客員准教授 2014 – 2015: 早稲田大学, 理工学術院, 准教授 … More 2012 – 2014: 早稲田大学, 理工学術院, 講師 2010: Waseda University, 理工学術院, 研究員 2009 – 2010: Waseda University, 理工学術院, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biological material science Except Principal Investigator Basic Section 90140:Medical technology assessment-related / Medium-sized Section 90:Biomedical engineering and related fields / Complex Systems Disease Theory / Basic Section 56010:Neurosurgery-related / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering / Neurosurgery / Medical engineering assessment / Cerebral neurosurgery / Pediatric surgery
Keywords	Principal Investigator 脳動脈瘤 / ひずみ / 病理 / 力学 / 動脈瘤 / 血管 / シミュレーション / 血管疲労 / 平滑筋細胞 / 病的リモデリング … More / 血栓 / リモデリング / 病態解明 / スティフネス / 細胞増殖 / ストレス / 細胞死 / 疾患 / 培養 / 血流 / せん断応力 / 衝突 / 血液 / マイクロ / 可視化 / 高速流体 / マイクロ流体 / 細胞破壊 / 溶血 / 赤血球 … More Except Principal Investigator 脳動脈瘤 / 医療機器 / 数値流体力学 / 破壊 / 溶血 / 赤血球 / 循環シミュレータ / バイパス術 / CFD / 数値流体解析 / 超音波顕微鏡 / リモデリング / 微視的力学場 / 組織反応 / 血管リモデリング / 血管組織 / 力学場 / 動脈瘤 / 血管 / バルーンカテーテル / 三次元ひずみ分布計測 / 圧縮試験 / カッティングバルーン / 冠動脈石灰化病変 / 生体組織モデリング / 血管内治療 / ひずみ分布計測 / 断層画像流速計測法 / 血管内カテーテル治療 / 三次元ひずみ計測 / 断層粒子画像流速計測法 / 数理モデリング / 血栓形成シミュレータ / ステント留置 / 留置シミュレータ / CFD解析 / 血栓化ダイナミクス / 動物モデル / 血栓形成の数理モデル / 走化性方程式系 / 数理モデル / 血栓過程 / ステント留置術 / 数値流体力学解析 / Navier-Stokes方程式 / 微量元素 / コラーゲン / 血行力学的変化 / 慢性炎症 / 血行力学的負荷 / 血液適合性 / 非臨床試験法 / 塞栓コイル / 脳動脈瘤モデル / 小容量拍動ポンプ / 血液循環シミュレータ / 可視化 / 膜損傷 / SHG / 細胞膜 / 損傷 / 膜 / SHG光 / MEMS / 光計測 / 破壊条件 / 脳神経疾疾患 / 流体力学 / 脳神経疾患 / 流体工学 / シミュレーション / 脳血行再建術 / 脳血管疾患 / 虚血性脳血管障害 / 医療技術評価 / 新規治療機器 / 医療技術評価学 / 生体吸収性ステント / 経皮的大動脈弁 / 国産人工弁 / レギュラトリーサイエンス / 医用機械工学 / PC-MRI / Norwood術 / 小児先天性心疾患 / せん断応力 / エネルギー損失 / Norwood / 先天性疾患 / 心血管 Less

Investigation of a cause of smooth-muscle-cell massive cell death and intrinsic tissue collapse by time-lapse analysis of vascular-wall mechanical fieldsPrincipal Investigator
- Principal Investigator
  
  八木高伸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Waseda University
血管組織内微視的力学場の定量による瘤発生機構解明と力学環境操作による病理応答制御
- Principal Investigator
  
  中村匡徳
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Nagoya Institute of Technology
Development of an experimental method for measuring three-dimensional strain distribution in calcified coronary artery model during balloon expansion
- Principal Investigator
  
  坪子侑佑
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  National Institute of Health Sciences
  Waseda University
Elucidation of hemodynamic factors resulting in chronic inflammation and degenerative changes in the wall of intracranial aneurysms
- Principal Investigator
  
  Kataoka Hiroharu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Cardiovascular Center Research Institute
Real-time quantitative prediction of cerebral-aneurysm growth with thrombosis-stratified vascular remodelingPrincipal Investigator
- Principal Investigator
  
  yagi takanobu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Waseda University
Visualization and quantification of cell membrane damages based on the measurement of second harmonic generation light
- Principal Investigator
  
  Nakamura Masanori
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Nagoya Institute of Technology
Development of the small blood circulation simulator to deepen the non-clinical evaluation of medical devices
- Principal Investigator
  
  Umezu Mitsuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Waseda University
Development and clinical application of a mathematical model to explain thrombogenic dynamics during the healing process of cerebral aneurysms
- Principal Investigator
  
  Sugiyama Yoshie
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  Osaka University
Quantification of failure conditions of a single red blood cell by non-contact mechanical tests using MEMS and chemiluminescene reactions
- Principal Investigator
  
  Nakamura Masanori
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Nagoya Institute of Technology
  Saitama University
Development of mock circulation systems for the evaluation of innovative medical devices
- Principal Investigator
  
  UMEZU Mitsuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical engineering assessment
- Research Institution
  Waseda University
Elucidation of blood flow control mechanisms for establishing a wide area of simulator of brain circulation after cerebral revascularization
- Principal Investigator
  
  Hiroharu Kataoka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyoto University
  National Cardiovascular Center Research Institute
Development of a supporting technology for bypass surgery for complex intracranial aneurysms using a blood flow simulator
- Principal Investigator
  
  KATAOKA HIROHARU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  National Cardiovascular Center Research Institute
臨床に直接貢献できる実用型小児先天性心疾患の血流シミュレーションシステムの構築
- Principal Investigator
  
  UMEZU Mitsuo
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatric surgery
- Research Institution
  Waseda University
Modeling of flow-induced hemolysis using single-cell real-time imaging in conjunction with high-speed microfluidic techbologyPrincipal Investigator
- Principal Investigator
  
  YAGI Takanobu
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Waseda University

All 2022 2020 2019 2017 2015 2011 2010 2009

All Journal Article Presentation

[Journal Article] Predicting the growth of middle cerebral artery bifurcation aneurysms using differences in the bifurcation angle and inflow coefficient2022
- Author(s)
  Miyata Takeshi、Kataoka Hiroharu、Shimizu Kampei、Okada Akihiro、Yagi Takanobu、Imamura Hirotoshi、Koyanagi Masaomi、Ishibashi Ryota、Goto Masanori、Sakai Nobuyuki、Hatano Taketo、Chin Masaki、Iwasaki Koichi、Miyamoto Susumu
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: Online ahead of print Pages: 1-9
- DOI
  10.3171/2022.8.jns22597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09367
[Journal Article] Association of bleb formation with peri-aneurysmal contact in unruptured intracranial aneurysms2022
- Author(s)
  Toru Satoh, Takanobu Yagi, Yoichi Sawada, Kenji Sugiu, Yu Sato, Isao Date
- Journal Title
  
  Scientific reports
  
  Volume: 12(1) Issue: 1 Pages: 6075-6075
- DOI
  10.1038/s41598-022-10064-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04455, KAKENHI-PROJECT-21K09100
[Journal Article] Hemodynamic and Histopathological Changes in the Early Phase of the Development of an Intracranial Aneurysm2020
- Author(s)
  KATAOKA Hiroharu、YAGI Takanobu、IKEDO Taichi、IMAI Hirohiko、KAWAMURA Koichi、YOSHIDA Kazumichi、NAKAMURA Masanori、AOKI Tomohiro、MIYAMOTO Susumu
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 60 Issue: 7 Pages: 319-328
- DOI
  10.2176/nmc.st.2020-0072
- NAID
  130007873264
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09367, KAKENHI-PROJECT-18KT0025
[Journal Article] Hemodynamic and histopathological changes in the early phase of the development of an intracranial aneurysm2020
- Author(s)
  Hiroharu Kataoka, Takanobu Yagi, Taichi Ikedo, Hirohiko Imai, Koichi Kawamura, Kazumichi Yoshida, Masanori Nakamura, Tomohiro Aoki, Susumu Miyamoto
- Journal Title
  
  Neurologia medico-chirurgica
  
  Volume: (in press)
- NAID
  130007873264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04455
[Journal Article] Systematic review of hemodynamic discriminators for ruptured intracranial aneurysms2019
- Author(s)
  Yagi Takanobu、Ishida Fujimaro、Shojima Masaaki、Anzai Hitomi、Fujimura Souichiro、Sano Takanori、Shinozaki Shun、Yamanaka Yuuma、Yamamoto Yuuto、Okamoto Yoshihiro、Ohta Makoto、Nakamura Masanori、on behalf of the CFD-BIO study group
- Journal Title
  
  Journal of Biorheology
  
  Volume: 33 Issue: 2 Pages: 53-64
- DOI
  10.17106/jbr.33.53
- NAID
  130007777456
- ISSN
  1867-0466, 1867-0474
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18355, KAKENHI-PROJECT-19H04455, KAKENHI-PROJECT-17J07496
[Journal Article] 脳血管バイパス術前後の血行動態の適応に関する検討2015
- Author(s)
  髙村兼司，八木高伸，渡邊幹彦，片岡大治，山本明秀，井口智史，飯田秀博，沼田尚己，中村匡徳，梅津光生
- Journal Title
  
  第27回バイオエンジニアリング講演会
  
  Volume: 14 Pages: 325-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592150
[Journal Article] Microscale visualization of erythrocyte deformation by colliding with a rigid surface using a high-speed impinging jet2009
- Author(s)
  S.Wakasa, T.Yagi, M.Umezu., et al.
- Journal Title
  
  ICBME, 2008, Proceedings 23
  
  Pages: 1422-1425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700474
[Journal Article] Single-cell real-time imaging of flow-induced hemolysis using high-speed microfluidic technology2009
- Author(s)
  T.Yagi, M.Umezu, et al.
- Journal Title
  
  IFMBE Proceedings 25/IV(Young Investigator Award 1st Prize
  
  Pages: 2337-2340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700474
[Journal Article] New challenge for studying flow-induced blood damage : macroscale modeling and microscale verification2009
- Author(s)
  T.Yagi, M.Umezu, et al.
- Journal Title
  
  ICBME 2008, Proceedings 23
  
  Pages: 1430-1433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] 前大脳動脈/嗅覚動脈接合部における脳動脈瘤の発生機序解明を目的とした血管組織内力学場の定量解析2022
- Author(s)
  鈴木孝祐，髙島匡輝，八木高伸，片岡大治，青木友浩，氏原嘉洋，杉田修啓，中村匡徳
- Organizer
  第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-19H04455
[Presentation] 術中ステレオ粒子画像解析を用いた心拍動による血管分岐部の微視的ひずみに関する検討2022
- Author(s)
  小谷優太，八木高伸，岡田宜佳，小山達也，岩崎清隆
- Organizer
  第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-19H04455
[Presentation] In vivo 実験による力学場の変化を起点とした血管構造破壊反応に関する検討2022
- Author(s)
  岡田，八木高伸，小谷，小山，岩崎清隆
- Organizer
  第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-19H04455
[Presentation] Systematic review of hemodynamic discriminators for ruptured intracranial aneurysms2020
- Author(s)
  Takanobu Yagi
- Organizer
  Interdisciplinary Cerebrovascular Symposium 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04455
[Presentation] 医療に活かす数値流体力学1：現状と展望2019
- Author(s)
  八木　高伸
- Organizer
  日本脳循環代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H04455
[Presentation] NEW INSIGHT INTO A TRIGGER OF INITIATING INTRACRANIAL ANEURYSMS USING A RAT MODEL2019
- Author(s)
  Takanobu Yagi, Wang Xinning, Koichi Kawamura, Taichi Ikedo, Kampei Shimizu, Tomohiro Aoki, Hirohiko Imai, Masanori Nakamura, Hiroharu Kataoka, Mitsuo Umezu
- Organizer
  6th International Conference on Computational and Mathematical Biomedical Engineering CMBE2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04455
[Presentation] 血管病のモデリング＆シミュレーション：病理学×理工学2019
- Author(s)
  八木　高伸
- Organizer
  第9回計算力学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H04455
[Presentation] VISUALIZATION AND QUANTIFICATION OF HEMOLYSIS AT A SINGLE CELLULAR SCALE2017
- Author(s)
  Masanori Nakamura, Takanobu Yagi
- Organizer
  5th Japan-Switzerland joint Biomechanics Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K12867
[Presentation] Another EBM (Engineering Based Medicine)2015
- Author(s)
  Umezu M, Iwsaki K, Sakaguchi K, Yagi T, Iseki H, Karube H, Sen I, Kasanuki H
- Organizer
  Interdisciplinary Cerebrovascular Symposium Intracranial Stent Meeting Program2015
- Place of Presentation
  Australia
- Year and Date
  2015-11-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03041
[Presentation] 超高速イメージングによる衝突速度に応じたヒト赤血球のリアルタイム破壊動態解析2011
- Author(s)
  秋元祐紀, 八木高伸, 関裕子, 木田大輔, 梅津光生
- Organizer
  第23回バイオエンジニアリング講演会講演論文集,pp383-4,第23回バイオエンジニアリング講演会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] 超高速イメージングによる衝突速度に応じた人赤血球のリアルタイム破壊動態解析2011
- Author(s)
  秋元祐紀, 八木高伸, 関裕子, 木田大輔, 梅津光生
- Organizer
  第23回バイオエンジニアリング講演会
- Place of Presentation
  熊本
- Year and Date
  2011-01-08
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] High-speed microfluidic study of colliding human erythrocytes at a single-cell real-time scale2010
- Author(s)
  T Yagi, Y Akimoto, Y Seki, D Kida, M Umezu
- Organizer
  6th World Congress on Biomechanics
- Place of Presentation
  Singapore
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] 超高速リアルタイムイメージングを用いた壁面衝突によるヒト赤血球の破壊動態観察2010
- Author(s)
  八木高伸, 秋元裕紀, 関裕子, 木田大輔, 梅津光生
- Organizer
  第48回日本人工臓器学会
- Place of Presentation
  仙台
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] High-speed microfluidic study of colliding human erythrocytes at a single-cell real-time scale2010
- Author(s)
  T.Yagi, M.Umezu, et al.
- Organizer
  Proceedings of 6^<th> World Congress on Biomechanics
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] 壁面衝突により座屈を伴い瞬時膜破壊に至る赤血球破壊のリアルタイム可視化計測2010
- Author(s)
  徳永夏子, 八木高伸, 秋元祐紀, 関裕子, 梅津光生
- Organizer
  第22回バイオエンジニアリング講演会講演論文集,pp208,第22回バイオエンジニアリング講演会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] Single-cell real-time imaging of florrinduced hemolysis using high-speed microfluidic technology2009
- Author(s)
  Takanobu Yagi
- Organizer
  World Congress on Medical Physics and Biomedical Engineering
- Place of Presentation
  ミュンヘンドイッ
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] Collision dynamics of red blood cens using high-speed impinging microjets2009
- Author(s)
  Takanobu Yagi
- Organizer
  10th International Conference on Fluid Control, Measurements, and Visualization
- Place of Presentation
  モスクワ,ロシア
- Year and Date
  2009-08-19
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] 高速マイクロジェットを用いた壁面衝突する赤血球の圧縮変形と破壊現象の可視化計測2009
- Author(s)
  八木高伸, 若狭翔太郎, 徳永夏子, 秋元祐紀, 梅津光生
- Organizer
  計算工学講演会論文集Vol.14
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] 高速リアルタイムイメージングによる壁面衝突する個々の赤血球の衝撃・破壊解析2009
- Author(s)
  八木高伸
- Organizer
  第47回日本人工臓器学会大会
- Place of Presentation
  新潟
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] 高速マイクロジェットを用いた壁面衝突する赤血球の圧縮変形と破壊現象の可視化計測2009
- Author(s)
  八木高伸
- Organizer
  計算工学講演会
- Place of Presentation
  東京
- Year and Date
  2009-05-12
- Data Source
  KAKENHI-PROJECT-21700474
[Presentation] 高速リアルタイムイメージングによる壁面衝突する個々の赤血球の衝撃・破壊解析2009
- Author(s)
  八木高伸, 徳永夏子, 秋元祐紀, 関裕子, 梅津光生
- Organizer
  第47回日本人工臓器学会大会予稿集Vol.38, No.2
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21700474

1. NAKAMURA Masanori (20448046)

# of Collaborated Projects: 9 results

# of Collaborated Products: 6 results
2. UMEZU Mitsuo (90132927)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. KATAOKA HIROHARU (40359815)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
4. 杉田修啓 (20532104)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
5. 岩崎清隆 (20339691)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 伊関洋 (90119892)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 松橋祐輝 (50754777)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 坪子侑佑 (40809399)

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12. Sugiyama Yoshie (60308210)

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YAGI Takanobu 八木 高伸

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Investigation of a cause of smooth-muscle-cell massive cell death and intrinsic tissue collapse by time-lapse analysis of vascular-wall mechanical fieldsPrincipal Investigator

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Real-time quantitative prediction of cerebral-aneurysm growth with thrombosis-stratified vascular remodelingPrincipal Investigator

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Modeling of flow-induced hemolysis using single-cell real-time imaging in conjunction with high-speed microfluidic techbologyPrincipal Investigator

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[Journal Article] Predicting the growth of middle cerebral artery bifurcation aneurysms using differences in the bifurcation angle and inflow coefficient2022

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YAGI Takanobu 八木高伸

[Presentation] 術中ステレオ粒子画像解析を用いた心拍動による血管分岐部の微視的ひずみに関する検討2022