Kimura Naoyuki 木村直行

… Alternative Names

KIMURA NAOYUKI 木村直行

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Researcher Number	20382898
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 自治医科大学, 医学部, 教授 2016 – 2019: 自治医科大学, 医学部, 准教授 2014 – 2015: 自治医科大学, 医学部, 講師 2012 – 2014: 自治医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55030:Cardiovascular surgery-related / Cardiovascular surgery / Thoracic surgery Except Principal Investigator Cardiovascular surgery / Basic Section 55030:Cardiovascular surgery-related / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 大動脈拡大 / 血管内皮細胞-血管平滑筋細胞共培養 / 数値流体力学研究 / nonA-nonB型大動脈解離 / 単培養モデル / 共培養モデル / 数値流体力学計算 / 剪断応力 / 大動脈解離 / せん断応力 … More / 数値流体力学 / 大動脈二尖弁化 / 胸部大動脈拡大 / ミニブタ / 二尖弁化 / 大動脈二尖弁 / アメリカ合衆国 / TGF / 網羅的遺伝子検索 / マイクロRNA / DNAマイクロアレイ / 網羅的遺伝子発現解析 / 急性大動脈解離 / microRNA … More Except Principal Investigator 血管平滑筋細胞 / 壁せん断応力 / 免疫応答 / 大動脈二尖弁 / 数値流体力学 / 大動脈瘤 / 先天性大動脈二尖弁 / MMP / 血管内皮細胞 / 共培養モデル / 急性大動脈解離 / 好中球 / 炎症反応 / 赤血球 / 溶血 / 網羅的遺伝子解析 / 壁剪断応力 / 慢性解離性大動脈瘤 / せん断応力 / 数値流体力学研究 / 慢性大動脈解離 / 大動脈リモデリング / 偽腔閉塞型 / 大動脈解離 / 偽腔形態 / 内皮細動－平滑筋細胞共培養モデル / 衝突噴流 / 心臓 / サルコペニア / 遺伝子 / 胸部大動脈拡大 / 数値流体力学計算 / 細胞間接着分子 / 遺伝子発現解析 / 剪断応力 / 白血球 / 好中球関連因子 / 大動脈瘤破裂 / 大動脈破裂 / 破壊 / MEMS / 光計測 / 破壊条件 / 大動脈炎症候群 / 大血管外科学 / 血管炎マウスモデル / IL-33 / 血管炎モデルマウス / 大動脈炎 / IL-1受容体アンタゴニスト欠損マウス / IL-25 / 大動脈炎モデルマウス / 大型血管炎 / 免疫学 / 人工臓器 / 循環器・高血圧 / 単球 / 経皮的大動脈弁移植術 / 術後炎症反応 / 経皮敵大動脈移植術 / 低侵襲心臓手術 / TAVI / サイトカイン / 経カテーテル大動脈移植殖術 / 大動脈弁置換術 / 大動脈弁狭窄症 / 閉鎖型人工心肺回路 / 心臓手術 / 破断ひずみ / 引張試験 / 引張り試験 / 胸部大動脈瘤 / シェアストレス / 遺伝子解析 / 先天性大動脈2尖弁 / 数値流体計算 / 上行大動脈瘤 / 大動脈弁二尖弁 Less

せん断応力負荷による血管平滑筋細胞の生体反応と大動脈解離偽腔拡大の関連性の検討
- Principal Investigator
  
  相澤啓
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Patient specific assessment of hemodynamics by computational fluid dynamics in patients with acute non-A non-B aortic dissectionPrincipal Investigator
- Principal Investigator
  
  木村直行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
偽腔閉塞型大動脈解離における急性期炎症と組織修復機序に関する検討
- Principal Investigator
  
  田中正史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Nihon University
Influence of shear stress on human aortic endothelial cell/smooth muscle cell interaction in bicuspid aortic valve aortopathy
- Principal Investigator
  
  Kawahito Koji
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Diagnosis of sarcopenia based on late outcomes after cardiovascular surgery
- Principal Investigator
  
  Okamura Homare
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Patient specific assessment of hemodynamics by computational fluid dynamics in patients with chronic aortic dissectionPrincipal Investigator
- Principal Investigator
  
  Kimura Naoyuki
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Investigation on the mechanisms of ruptured acute aortic dissection based on immune response analyses
- Principal Investigator
  
  TANAKA Masashi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Nihon University
Characterization of wall shear stress sensitive genes in bicuspid aortic valve aortopathy
- Principal Investigator
  
  Koji Kawahito
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
Suppressed immune response following minimally invasive cardiac surgery
- Principal Investigator
  
  Yamaguchi Atsushi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice
- Principal Investigator
  
  ITOH Satoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
Quantification of failure conditions of a single red blood cell by non-contact mechanical tests using MEMS and chemiluminescene reactions
- Principal Investigator
  
  Nakamura Masanori
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Nagoya Institute of Technology
  Saitama University
Bicuspidalization of the native tricuspid aortic valve using a miniature pigPrincipal Investigator
- Principal Investigator
  
  KIMURA Naoyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
Patient-specific assessment of hemodynamics by computational fluid dynamics and gene expression profiling in patients with bicuspid aortopathy.
- Principal Investigator
  
  KAWAHITO KOJI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
Quantification of hemolytic conditions using pico-photo sensing of chemoluminescence caused by hemoglobin leakage
- Principal Investigator
  
  NAKAMURA Masanori
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Saitama University
Efficacy of closed-circuit cardiopulmonary bypass system assessed by gene expression profiling
- Principal Investigator
  
  Yamaguchi Atsushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
Integrated Analysis of microRNA and mRNA Gene Expression Profiling for Non-syndromic Acute Type A Aortic DissectionPrincipal Investigator
- Principal Investigator
  
  KIMURA NAOYUKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Jichi Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Appropriate sizing of the frozen elephant trunk: How to predict proximal descending aortic diameter prior to dissection?2024
- Author(s)
  1.Kitada Y, Okamura H, Yamauchi T, Nishi S, Arakawa M, Kimura N, Kawahito K, Yamaguchi A.
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: － Issue: 2 Pages: 542-551.e3
- DOI
  10.1016/j.jtcvs.2024.01.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09154
[Journal Article] Impact of residual entry tears in the descending aorta after type-A dissection2024
- Author(s)
  Koji Kawahito, Naoyuki Kimura, Atsushi Yamaguchi, Kei Aizawa
- Journal Title
  
  Annals of Thoracic Surgery
  
  Volume: －
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09154
[Journal Article] Thoracic endovascular aortic repair for acute aortic dissection complicated by mesenteric malperfusion: an evaluation by computational fluid dynamics2024
- Author(s)
  Kimura Naoyuki、Imada Shuta、Hori Daijiro、Nakamura Masanori
- Journal Title
  
  Interdisciplinary CardioVascular and Thoracic Surgery
  
  Volume: 38 Issue: 3
- DOI
  10.1093/icvts/ivae047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08828
[Journal Article] Non-A Non-B Aortic Dissection Complicated with Right Aortic Arch Treated by Extended Thoracic Aortic Repair2023
- Author(s)
  Hori Y, Kimura N, Yamamoto T, Yamauchi T, Hori D, Shiraishi M, Yamaguchi A
- Journal Title
  
  Kyobu Geka
  
  Volume: 76 Pages: 924-927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08828
[Journal Article] A Compressed Collagen Construct for Studying Endothelial-Smooth Muscle Cell Interaction under High Shear Stress2022
- Author(s)
  Yuya Hiroshima, Yuki Oyama, Kaoru Sawasaki, Masanori Nakamura, Naoyuki Kimura, Koji Kawahito, Hiromichi Fujie, Naoya Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09154
[Journal Article] Compressed Collagen Construct for Studying Endothelial Smooth Muscle Cell Interaction Under High Shear Stress2022
- Author(s)
  Hiroshima Y, Oyama Y, Sawasaki K, Nakamura M, Kimura N, Kawahito K, Fujie H
- Journal Title
  
  Ann Biomed Eng.
  
  Volume: - Issue: 8 Pages: 951-963
- DOI
  10.1007/s10439-022-02972-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10763, KAKENHI-PROJECT-20K09154
[Journal Article] Bicuspidalization of the Native Tricuspid Aortic Valve: A Porcine in Vivo Model of Bicuspid Aortopathy2022
- Author(s)
  Kimura N, Itagaki R, Nakamura M, Tofrizal A, Yatabe M, Yoshizaki T, Kokubo R, Hishikawa S, Kunita S, Adachi H, Misawa Y, Yashiro T, Kawahito K.
- Journal Title
  
  Ann Vasc Dis
  
  Volume: 15 Issue: 1 Pages: 37-44
- DOI
  10.3400/avd.oa.21-00116
- ISSN
  1881-641X, 1881-6428
- Year and Date
  2022-03-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09154
[Journal Article] False lumen/true lumen wall pressure ratio is increased in acute non-A non-B aortic dissection2022
- Author(s)
  Kimura Naoyuki、Nakamura Masanori、Takagi Reiya、Mieno Makiko Naka、Yamaguchi Atsushi、Czerny Martin、Beyersdorf Friedhelm、Kari Fabian Alexander、Rylski Bartosz
- Journal Title
  
  Interactive CardioVascular and Thoracic Surgery
  
  Volume: 35 Issue: 3
- DOI
  10.1093/icvts/ivac138
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08828
[Journal Article] Influence of residual primary entry following the tear-oriented strategy for acute type A aortic dissection2021
- Author(s)
  Kawahito K, Aizawa K, Kimura N, Yamaguchi A, Adachi H
- Journal Title
  
  Euro J Cardiothorac Surg
  
  Volume: - Issue: 5 Pages: 1077-84
- DOI
  10.1093/ejcts/ezab456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09154
[Journal Article] Factors related to white blood cell elevation in acute type A aortic dissection2020
- Author(s)
  Suzuki K，Kimura N, Mieno M, Hori D, Sezai A, Yamaguchi A, Tanaka M
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 2 Pages: e0228954-e0228954
- DOI
  10.1371/journal.pone.0228954
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10768
[Journal Article] Preoperative sarcopenia is associated with late mortality after off-pump coronary artery bypass grafting2020
- Author(s)
  Okamura H, Kimura N, Mieno M, Yuri K, Yamaguchi A
- Journal Title
  
  Eur J Cardiothorac Surg
  
  Volume: 58 Issue: 1 Pages: 121-129
- DOI
  10.1093/ejcts/ezz378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09276
[Journal Article] Effect of transcatheter aortic valve implantation on the immune response associated with surgical aortic valve replacement.2020
- Author(s)
  Kimura N, Nomura Y, Aomatsu A, Matsuda A, Imamura Y, Taniguchi Y, Hori D, Morishita Y, Fujita H, Yuri K, Matsumoto K, Yamaguchi A.
- Journal Title
  
  American Journal of Cardiology
  
  Volume: － Pages: 35-44
- DOI
  10.1016/j.amjcard.2020.04.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10636
[Journal Article] Utility of Double Arterial Cannulation for Surgical Repair of Acute Type A Dissection2020
- Author(s)
  Kusadokoro S, Kimura N, Hori D, Hattori M, Matsunaga W, Itagaki R, Yuri K, Mieno M, Nakamura M, Yamaguchi A.
- Journal Title
  
  European Journal of Cardiothoracic Surgery
  
  Volume: 57 Issue: 6 Pages: 1068-1075
- DOI
  10.1093/ejcts/ezaa007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08770
[Journal Article] Outcomes of Early-Onset Acute Type A Aortic Dissection　― Influence of Etiologic Factors ―2019
- Author(s)
  Kimura N, Aizawa K, Kawahito K, Itagaki R, Yamaguchi A, Misawa Y, Siepe M, Czerny M, Beyersdorf F, Kari FA, Rylski B
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 2 Pages: 285-294
- DOI
  10.1253/circj.CJ-18-0969
- NAID
  130007557087
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-01-25
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08770
[Journal Article] Successful Surgical Treatment of Giant Coronary Artery Aneurysm and Concomitant Coronary Artery Fistula to the Pulmonary Artery2018
- Author(s)
  Suzuki K，Kimura N, Sezai A, Unosawa S, Taoka M, Osaka S, Tanaka M
- Journal Title
  
  The Heart Surgery Forum
  
  Volume: 21 Issue: 4 Pages: E247-E249
- DOI
  10.1532/hsf.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10768
[Journal Article] Characteristics and Treatment Outcomes of Acute Type A Aortic Dissection With Elevated D‐Dimer Concentration2018
- Author(s)
  Itagaki R, Kimura N, Mieno M, Hori D, Itoh S, Akiyoshi K, Yuri K, Tanno K, Kawahito K, Yamaguchi A
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 7 Issue: 14
- DOI
  10.1161/jaha.118.009144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10768
[Journal Article] Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with bicuspid aortopathy.2017
- Author(s)
  Kimura N, Nakamura M, Komiya K, Nishi S, Yamaguchi A, Tanaka O, Misawa Y, Adachi H, Kawahito K.
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: 153 Issue: 4 Pages: S52-S62.e3
- DOI
  10.1016/j.jtcvs.2016.12.033
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462117
[Journal Article] Blood flow competition after aortic valve bypass: an evaluation using computational fluid dynamics2017
- Author(s)
  Kawahito Koji、Kimura Naoyuki、Komiya Kenji、Nakamura Masanori、Misawa Yoshio
- Journal Title
  
  Interact Cardiovasc Thorac Surg
  
  Volume: 24 Pages: ivw428-ivw428
- DOI
  10.1093/icvts/ivw428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462117
[Journal Article] Gene expression profiling of acute type A aortic dissection combined with in vitro assessment.2017
- Author(s)
  Kimura N, Futamura K, Arakawa M, Okada N, Emrich F, Okamura H, Sato T, Shudo Y, Koyano TK, Yamaguchi A, Adachi H, Matsuda A, Kawahito K, Matsumoto K, Fischbein MP.
- Journal Title
  
  European Journal of Cardio-Thoracic Surgery
  
  Volume: 52 Issue: 4 Pages: 810-817
- DOI
  10.1093/ejcts/ezx095
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10053, KAKENHI-PROJECT-17K10768, KAKENHI-PROJECT-17K11500, KAKENHI-PROJECT-24791469, KAKENHI-PROJECT-17K10166
[Presentation] 壁せん断応力下の血管平滑筋細胞の形態応答における内皮細胞間との相互作用2024
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、山﨑雅史、藤江裕道、坂元尚哉．
- Organizer
  第63回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 内皮細胞間との相互作用による血管平滑筋細胞への力学環境情報伝達．2024
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、山﨑雅史、藤江裕道、坂元尚哉
- Organizer
  日本機械学会2024年度年次大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] Interaction with endothelial cells induces vascular smooth muscle cell orientation under wall shear stress condition.2024
- Author(s)
  Sawasaki K, Nakamura M, Kimura N, Kawahito K, Yamazaki M, Fujie H, Sakamoto N.
- Organizer
  Biomechanics, Bioengineering and Biotransport Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力に対する血管内皮細胞内アクチンフィラメント構造の変化.2024
- Author(s)
  山﨑瑠海, 髙橋幸慈, 沢崎薫, 中村匡徳, 木村直行, 川人宏次, 坂元尚哉.
- Organizer
  第36回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 特異的血流環境を模擬した高壁せん断応力が血管モデル内平滑筋細胞の表現型転換へ及ぼす影響の評価2023
- Author(s)
  沢崎薫，中村匡徳，木村直行, 川人宏次，藤江裕道，坂元尚哉
- Organizer
  第65回日本平滑筋学会総会 (東京, 2023年8月4-5日)
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] 腹部臓器灌流障害を合併した急性B型大動脈解離に対するTEVAR：数値流体力学計算による治療効果判定2023
- Author(s)
  2.木村直行，今田修多, 堀大治郎, 山本貴裕, 山口敦司, 小宮賢士, 中村匡徳.
- Organizer
  第51回日本血管外科学会学術総会 (東京, 2023年5月31日-6月2日)
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] Utility of thoracic endovascular aortic repair for acute aortic dissection complicated with mesenteric malperfusion; an evaluation using computational fluid dynamic2023
- Author(s)
  4.Kimura N, Imada S, Hori D, Yamamoto T, Yamaguchi A, Komiya K, Nakamura M
- Organizer
  37th EACTS Annual Meeting 2023 (Vienna, Austria. Oct 4-7, 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] Outcomes of extracorporeal membrane oxygenation for acute type A aortic dissection complicated with profound shock2023
- Author(s)
  木村直行, 中野光規, 野村陽平, 堀大治郎, 白石学, 百瀬直樹, 山口敦司
- Organizer
  第51回日本血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08849
[Presentation] Vascular Smooth Muscle Cell Orientation Induced by Cocultured Endothelial Cells Subjected to Wall Shear Stress2023
- Author(s)
  Kaoru Sawasaki, Masanori Nakamura, Naoyuki Kimura, Koji Kawahito, Hiromichi Fujie, Naoya Sakamoto.
- Organizer
  2023 BMES Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力に対する内皮細胞を介した血管平滑筋細胞の形態変化．2023
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉．壁せん断応力に対する内皮細胞を介した血管平滑筋細胞の形態変化．
- Organizer
  日本機械学会2023年度年次大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力環境下における内皮細胞と共培養した血管平滑筋細胞の形態変化2023
- Author(s)
  5.沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  第62回日本生体医工学会大会 (名古屋, 2023年5月18-20日)
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] 血管内皮細胞によるNO産生と衝突噴流環境との関係．2023
- Author(s)
  沢崎薫、山﨑瑠海、髙橋幸慈、中村匡徳、木村直行、川人宏次、坂元尚哉．
- Organizer
  第46回バイオレオロジー学会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力に対する内皮細胞を介した血管平滑筋細胞の形態変化2023
- Author(s)
  沢崎薫，中村匡徳，木村直行，川人宏次，藤江裕道，坂元尚哉
- Organizer
  日本機械学会2023年度年次大会 (東京, 2023年9月3－6日)
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] 壁せん断応力環境下における内皮細胞と共培養した血管平滑筋細胞の形態変化．2023
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉．
- Organizer
  第62回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] Effect of false lumen status on systemic inflammatory response induced by acute aortic dissection2022
- Author(s)
  町井洋二郎、木村直行、堀大治郎、白石学、山口敦司、田中正史
- Organizer
  第75回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08849
[Presentation] 腹部臓器灌流障害を合併した急性B型大動脈解離に対するTEVAR：computational fluid dynamicsによる治療効果判定2022
- Author(s)
  木村直行、今田修多、堀大治郎、山本貴裕、山口敦司、小宮賢士、中村匡徳
- Organizer
  第51回日本血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] Study on Effect of Extreme Shear Condition on Endothelial Cell and Smooth muscle Cell Functions using Compressed Collagen Construct.2022
- Author(s)
  1．Sakamoto N, Oyama Y, Sawasaki K, Hiroshima Y, Nakamura M, Kimura N, Kawahito K, Fujie H
- Organizer
  9th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力-法線方向動圧組み合わせ環境が血管内皮細胞に及ぼす影響．2022
- Author(s)
  髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉．
- Organizer
  第45回日本バイオレオロジー学会年会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 急性A型解離術後遠隔期TEVARの治療成績2022
- Author(s)
  住吉力、木村直行、堀大治郎、中野光規、野村陽平、白石学、山口敦司
- Organizer
  第31回日本大動脈外科研究会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] Phenotypic States of Smooth Muscle Cells in a Coculture Model under Higher Wall Shear Stress Condition2022
- Author(s)
  Sawasaki K, Nakamura M, Kimura N, Kawahito K, Fujie H, Sakamoto N
- Organizer
  2022 BMES Annual Meeting
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] False lumen thrombosis may attenuate the systemic inflammatory response triggered by acute aortic dissection2022
- Author(s)
  Kimura N, Machii Y, Matsuda A, Eguchi N, Hori D, Shiraishi M, Yamaguchi A, Matsumoto K, Tanaka M
- Organizer
  36th Annual Meeting of European Association for Cardiothoracic Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08849
[Presentation] 衝突噴流に伴う力学刺激の組み合わせ環境が血管内皮細胞に及ぼす影響2022
- Author(s)
  髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉
- Organizer
  第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 衝突噴流に伴う力学刺激の組み合わせ環境が血管内皮細胞に及ぼす影響2022
- Author(s)
  髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉
- Organizer
  第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 高壁せん断応力が内皮細胞と共培養した血管平滑筋細胞の表現型へ及ぼす影響2022
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉
- Organizer
  第61回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] FET時代の解離の治療戦略 - 年齢に基づいたIII型逆行性解離に対する遠位側拡大手術の適応2022
- Author(s)
  川人宏次、相澤啓、木村直行、山口敦司、安達秀雄
- Organizer
  第52回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 高壁せん断応力を負荷した共培養血管モデルにおける平滑筋細胞の表現型2022
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉
- Organizer
  日本機械学会 2022年度年次大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] Study on Effect of Extreme Shear Condition on Endothelial Cell and Smooth muscle Cell Functions using Compressed Collagen Construct2022
- Author(s)
  Sakamoto N, Oyama Y, Sawasaki K, Hiroshima Y, Nakamura M, Kimura N, Kawahito K, Fujie H.
- Organizer
  9th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with acute non-A non-B aortic dissection2021
- Author(s)
  Naoyuki Kimura, Masanori Nakamura, Reiya Takagi, Takahiro Yamamoto, Daijiro Hori, Atsushi Yamaguchi, Bartosz Rylski
- Organizer
  第74回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] 弁形態分析に基づく大動脈二尖弁狭窄症例の上行大動脈拡大と治療成績に関する検討2021
- Author(s)
  木村直行,　堀大治郎, 草処翔,　清水寿和, 　　野村陽平,　白石学,　川人宏次, 山口敦司
- Organizer
  第49回日本血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 急性A型大動脈解離でのhemiarch repair における選択的順行性脳灌流の有用性に関する検討2021
- Author(s)
  木村直行、百瀬直樹、堀大治郎、白石学、山口敦司
- Organizer
  第74回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] 弁形態分析に基づく大動脈二尖弁狭窄症例の上行大動脈拡大と治療成績に関する検討2021
- Author(s)
  木村直行,　堀大治郎, 草処翔,　清水寿和, 　　野村陽平,　白石学,　川人宏次, 山口敦司
- Organizer
  第49回日本血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] Effect of False Lumen Status on Systemic Inflammatory Responses of Acute Aortic Dissection2021
- Author(s)
  Kimura N, Machii Y, Matsuda A, Hori D, Shiraishi M, Yamaguchi A, Matsumoto K, Tanaka M
- Organizer
  American Heart Association Scientific Sessions 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08849
[Presentation] 弓部大動脈奇形を有する急性A型大動脈解離症例の臨床像と治療成績に関する検討2021
- Author(s)
  山本貴裕、木村直行、白杉岳洋、野村陽平、荒川衛、野中崇央、堀大治郎、白石学、山口敦司
- Organizer
  第52回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] 大動脈二尖弁性狭窄と大動脈三尖弁性狭窄の治療成績とaortic stiffnessに関する検討2021
- Author(s)
  木村直行, 堀大治郎, 草処翔, 清水寿和, 白石学,川人宏次, 山口敦司
- Organizer
  第51回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 急性A型大動脈解離術後遠隔期の遠位側追加（再）手術の治療成績2021
- Author(s)
  木村直行、堀大治郎、山本貴裕'、玉井宏一、白杉岳洋、野村陽平、荒川衛、野中崇央、白石学、山口敦司
- Organizer
  第74回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with acute non-A non-B aortic dissection2021
- Author(s)
  Naoyuki Kimura, Masanori Nakamura, Reiya Takagi, Atsushi Yamaguchi, Martin Czerny, Friedhelm Beyersdorf, Fabian Alexander Kari, Bartosz Rylski
- Organizer
  The 35th EACTS Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08828
[Presentation] 大動脈二尖弁性狭窄と大動脈三尖弁性狭窄の治療成績とaortic stiffnessに関する検討2021
- Author(s)
  木村直行, 堀大治郎, 草処翔, 清水寿和, 白石学,川人宏次, 山口敦司
- Organizer
  第51回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 急性Non-A Non-B大動脈解離の臨床像と数値流体力学計算による血流解析2020
- Author(s)
  木村直行、外山豊、服部将大、堀大治郎、山口敦司、川人宏次、中村匡徳
- Organizer
  第51回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] 内皮-平滑筋細胞共培養モデルのMMP産生に対する高壁せん断応力環境の影響2020
- Author(s)
  坂元尚哉，大山侑樹，中村匡徳，木村直行，川人宏次，山崎雅史，藤江裕道
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 衝突噴流が血管内皮細胞間接着に及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，川人宏次，坂元尚哉
- Organizer
  日本機械学会第33回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 衝突噴流が血管内皮細胞間接着に及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，川人宏次，坂元尚哉
- Organizer
  日本機械学会第33回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 内皮-平滑筋細胞共培養モデルのMMP産生に対する高壁せん断応力環境の影響2020
- Author(s)
  坂元尚哉，大山侑樹，中村匡徳，木村直行，川人宏次，山崎雅史，藤江裕道
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 急性Ａ型大動脈解離に合併する凝固障害：関連因子と治療経過に及ぼす影響に関する検討2020
- Author(s)
  藤森智成、木村直行、堀大治郎、野村陽平、草処翔、板垣翔、白石学、山口敦司
- Organizer
  第48回日本血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10768
[Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，川人宏次，坂元尚哉
- Organizer
  生体医工学会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，　川人宏次，坂元尚哉
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，　川人宏次，坂元尚哉
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 圧縮コラーゲン組織を用いた共培養モデルに対する高壁せん断応力の影響2019
- Author(s)
  大山侑樹, 中村匡徳, 木村直行, 川人宏次, 山崎雅史, 藤江裕道, 坂元尚哉
- Organizer
  日本機械学会第 32 回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] Utility of double arterial cannulation for surgical repair of acute type a dissection2019
- Author(s)
  Kusadokoro S, Kimura N, Hori D, Hattori M, Yuri K, Nakamura M, Yamaguchi A
- Organizer
  33rd European Association for Cardiothoracic Surgery Annual Meeting, Lisbon, Portugal. October 5, 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] Transcatheter aortic valve replacement suppresses postoperative immune responses2019
- Author(s)
  Nomura Y, Kimura N, Aomatsu A, Matsuda A, Imamura Y, Taniguchi Y, Hori D, Shiraishi M, Sakakura K, Wada H, Fujita H, Morishita Y, Yuri K, Matsumoto K, Yamaguchi A
- Organizer
  American Heart Association Scientific Sessions 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10636
[Presentation] Utility of computational fluid dynamics for thoracic aortic pathology in the era of precision medicine2019
- Author(s)
  NAOYUKI KIMURA, KOKI KAWAHITO, DAJIRO HORI, KOICHI YURI, ATSUSHI YAMAGUCHI, YUUKI OHYAMA, NAOYA SAKAMOTO, MASANORI NAKAMURA
- Organizer
  第83回日本循環器病学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] TAVRによる術後免疫応答抑制に関する研究2019
- Author(s)
  野村陽平、木村直行、青松昭徳、松田明生、今村有佑、谷口陽介、堀大治郎、白石　学、坂倉建一、和田　浩、藤田英雄、由利康一、松本健治、山口敦司
- Organizer
  第72回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10636
[Presentation] 血管内皮細胞のＭＭＰおよびeNOS産生に対する超高壁せん断応力の影響2018
- Author(s)
  坂元尚哉，大山侑樹，中村匡徳，木村直行
- Organizer
  第41回日本バイオレオロジー学会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 血管内皮細胞の遊走および剥離に対する衝突流れの場の影響2018
- Author(s)
  堀江悠太, 大山侑樹, 中村匡徳, 木村直行, 川人宏次, 坂元尚哉
- Organizer
  日本機械学会第31回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] ランチョンセミナー講演；安全性を重視した簡便な右開胸MICS手術マニュアル2018
- Author(s)
  山口敦司，由利康一，木村直行，堀大治郎，板垣　翔，佐藤哲也，野村陽平，今村有佑，草処　翔
- Organizer
  第71回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10636
[Presentation] 慢性大動脈解離に対するステント治療におけるcomputational fluid dynamics解析の有用性2018
- Author(s)
  木村直行　田中高志　服部将大　中村匡徳
- Organizer
  第11回血流会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] 超高壁せん断応力による血管内皮細胞のMMPおよびeNOS産生の変化2018
- Author(s)
  大山侑樹，中村匡徳，木村直行，坂元尚哉
- Organizer
  日本機械学会 2018年度年次大会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 急性大動脈解離診療におけるステントグラフト治療の有効性2018
- Author(s)
  木村直行　由利康一　堀大治郎　白石学　野中崇央　野村陽平　松本春信　山口敦司
- Organizer
  第80回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] UTILITY OF COMPUTATIONAL FLUID DYNAMICS FOR THORACIC AORTIC PATHOLOGY IN THE ERA OF PRECISION MEDICINE2018
- Author(s)
  NAOYUKI KIMURA, KOJI KAWAHITO, DAIJIRO HORI, KOICHI YURI, ATSUSHI YAMAGUCHI, YUUKI OHYAMA, NAOYA SAKAMOTO, MASANORI NAKAMURA
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08770
[Presentation] ミニブタを使用した大動脈二尖弁化モデルによる大動脈壁の血流解析2017
- Author(s)
  吉崎隆道　木村直行　中村匡徳　小宮賢士　矢田部恵　Tofrizal Alimuddin
- Organizer
  第47回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10246
[Presentation] 衝突流による赤血球破壊とそれに伴うヘモグロビン漏出の定量2017
- Author(s)
  眞木敬太, 石井克宗，木村直行，中村匡徳
- Organizer
  関東学生会第５６回学生員卒業研究発表講演会
- Place of Presentation
  東京理科大学（東京都　葛飾区）
- Data Source
  KAKENHI-PROJECT-16K12867
[Presentation] 超高齢者の大動脈弁狭窄症に対するTAVRとSAVRの治療成績2017
- Author(s)
  今村有佑、由利康一、木村直行、松永渉、板垣翔、堀大治郎、松本春信、讃井將満、山口敦司
- Organizer
  第70回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10636
[Presentation] Gene expression profiling and in vitro human aortic cell experiments for non-syndromic acute type A aortic dissection2016
- Author(s)
  Kimura N, Futamura K, Arakawa M, Okada N, Emrich F, Okamura H, Sato T, Shudo Y, Koyano TK, Matsuda A, Yamaguchi A, Adachi H, Matsumoto K, Fischbein MP
- Organizer
  30th European Association for Cardiothoracic Surgery, Annual Meeting
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2016-10-02
- Data Source
  KAKENHI-PROJECT-24791469
[Presentation] Patient-specific evaluation of hemodynamics in bicuspid aortopathy by means of magnetic resonance imaging based computational fluid dynamics simulation.2016
- Author(s)
  ５．Kimura N, Kawahito K, Komiya K, Numata N, Yamaguchi A, Misawa Y, Nakamura M, Adachi H.
- Organizer
  AATS Aortic Symposium 2016
- Place of Presentation
  New York
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462117

1. NAKAMURA Masanori (20448046)

# of Collaborated Projects: 9 results

# of Collaborated Products: 50 results
2. KAWAHITO KOJI (90281740)

# of Collaborated Projects: 6 results

# of Collaborated Products: 39 results
3. NAKAE Susumu (60450409)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. MATSUMOTO Kenji (60181765)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. Yamaguchi Atsushi (50265287)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
6. 坂元尚哉 (20361115)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
7. FUTAMURA Kyoko (60596956)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. TANAKA Masashi (80382927)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
9. 吉崎隆道 (20743115)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
10. ITOH Satoshi (30382881)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. Okamura Homare (70438646)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. 相澤啓 (50398517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. UJIHARA Yoshihiro (80610021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAGI Takanobu (00468852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 吉川洋史 (50551173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 田岡誠 (20814213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 大幸俊司 (20748149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 板垣翔 (40639035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 宇野澤聡 (60451324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 荒川衛 (30624647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. FISCHBEIN Michael P.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Kimura Naoyuki 木村 直行

KIMURA NAOYUKI 木村 直行

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Patient specific assessment of hemodynamics by computational fluid dynamics in patients with acute non-A non-B aortic dissectionPrincipal Investigator

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Patient specific assessment of hemodynamics by computational fluid dynamics in patients with chronic aortic dissectionPrincipal Investigator

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Bicuspidalization of the native tricuspid aortic valve using a miniature pigPrincipal Investigator

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Kimura Naoyuki 木村直行

KIMURA NAOYUKI 木村直行