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Kawahito Koji  川人 宏次

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… Alternative Names

KAWAHITO KOJI  川人 宏次

川人 宏次  カワヒト コウジ

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Researcher Number 90281740
Other IDs
Affiliation (Current) 2022: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2014 – 2021: 自治医科大学, 医学部, 教授
1998 – 1999: 自治医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Cardiovascular surgery / Thoracic surgery / Basic Section 55030:Cardiovascular surgery-related
Except Principal Investigator
Cardiovascular surgery / Cardiovascular medicine
Keywords
Principal Investigator
数値流体力学 / 大動脈二尖弁 / 壁せん断応力 / 血管内皮細胞 / 血管平滑筋細胞 / MMP / 先天性大動脈二尖弁 / 大動脈瘤 / 体外循環 / アポトーシス … More / 心臓手術 / リンパ球 / PCPS / 大動脈弁二尖弁 / 上行大動脈瘤 / 数値流体計算 / 壁剪断応力 / 網羅的遺伝子解析 / 先天性大動脈2尖弁 / 遺伝子解析 / シェアストレス / 胸部大動脈瘤 / 剪断応力 / 共培養モデル / 遺伝子発現解析 / 細胞間接着分子 / 数値流体力学計算 / 胸部大動脈拡大 / 遺伝子 / 内皮細動-平滑筋細胞共培養モデル … More
Except Principal Investigator
夜間血圧 / スリープサージ / トリガー血圧計 / IT家庭血圧モニタリング / 基底血圧 / 夜間高血圧 / 大動脈二尖弁 / 大動脈拡大 / 二尖弁化 / ミニブタ / 胸部大動脈拡大 / 大動脈二尖弁化 / 数値流体力学 / せん断応力 / 大型血管炎 / 大動脈炎モデルマウス / IL-25 / IL-1受容体アンタゴニスト欠損マウス / 大動脈炎 / 血管炎モデルマウス / IL-33 / 血管炎マウスモデル / 大血管外科学 / 大動脈炎症候群 Less
  • Research Projects

    (7 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (23 People)
  •  Influence of shear stress on human aortic endothelial cell/smooth muscle cell interaction in bicuspid aortic valve aortopathyPrincipal Investigator

    • Principal Investigator
      川人 宏次
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Jichi Medical University
  •  Characterization of wall shear stress sensitive genes in bicuspid aortic valve aortopathyPrincipal Investigator

    • Principal Investigator
      Koji Kawahito
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Jichi Medical University
  •  IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice

    • Principal Investigator
      ITOH Satoshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Jichi Medical University
  •  Bicuspidalization of the native tricuspid aortic valve using a miniature pig

    • Principal Investigator
      KIMURA Naoyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Jichi Medical University
  •  Research and development of IT multi-trigger nocturnal home blood pressure monitoring system and clinical study

    • Principal Investigator
      Kario Kazuomi
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Jichi Medical University
  •  Patient-specific assessment of hemodynamics by computational fluid dynamics and gene expression profiling in patients with bicuspid aortopathy.Principal Investigator

    • Principal Investigator
      KAWAHITO KOJI
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Jichi Medical University
  •  体外循環時のリンパ球減少におけるアポトーシスの関与Principal Investigator

    • Principal Investigator
      川人 宏次
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Thoracic surgery
    • Research Institution
      Jichi Medical University

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] A Compressed Collagen Construct for Studying Endothelial-Smooth Muscle Cell Interaction under High Shear Stress2022

    • Author(s)
      Yuya Hiroshima, Yuki Oyama, Kaoru Sawasaki, Masanori Nakamura, Naoyuki Kimura, Koji Kawahito, Hiromichi Fujie, Naoya Sakamoto
    • Journal Title

      Annals of Biomedical Engineering

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Journal Article] Compressed Collagen Construct for Studying Endothelial Smooth Muscle Cell Interaction Under High Shear Stress2022

    • Author(s)
      Hiroshima Y, Oyama Y, Sawasaki K, Nakamura M, Kimura N, Kawahito K, Fujie H
    • Journal Title

      Ann Biomed Eng.

      Volume: -

    • DOI

      10.1007/s10439-022-02972-7

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Journal Article] Influence of residual primary entry following the tear-oriented strategy for acute type A aortic dissection2021

    • Author(s)
      Kawahito K, Aizawa K, Kimura N, Yamaguchi A, Adachi H
    • Journal Title

      Euro J Cardiothorac Surg

      Volume: -

    • DOI

      10.1093/ejcts/ezab456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Journal Article] Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with bicuspid aortopathy2017

    • Author(s)
      Kimura N, Nakamura M, Komiya K, Nishi S, Yamaguchi A, Tanaka O, Misawa Y, Adachi H, Kawahito K.
    • Journal Title

      J Thorac Cardiovasc Surg

      Volume: 153

    • DOI

      10.1016/j.jtcvs.2016.12.033

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462117
  • [Journal Article] Blood flow competition after aortic valve bypass: an evaluation using computational fluid dynamics2017

    • Author(s)
      Kawahito Koji、Kimura Naoyuki、Komiya Kenji、Nakamura Masanori、Misawa Yoshio
    • Journal Title

      Interact Cardiovasc Thorac Surg

      Volume: 24

    • DOI

      10.1093/icvts/ivw428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462117
  • [Presentation] 高壁せん断応力を負荷した共培養血管モデルにおける平滑筋細胞の表現型2022

    • Author(s)
      沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉
    • Organizer
      日本機械学会 2022年度年次大会
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 衝突噴流に伴う力学刺激の組み合わせ環境が血管内皮細胞に及ぼす影響2022

    • Author(s)
      髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉
    • Organizer
      第32回バイオフロンティア講演会
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 衝突噴流に伴う力学刺激の組み合わせ環境が血管内皮細胞に及ぼす影響2022

    • Author(s)
      髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉
    • Organizer
      第32回バイオフロンティア講演会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] Study on Effect of Extreme Shear Condition on Endothelial Cell and Smooth muscle Cell Functions using Compressed Collagen Construct.2022

    • Author(s)
      1.Sakamoto N, Oyama Y, Sawasaki K, Hiroshima Y, Nakamura M, Kimura N, Kawahito K, Fujie H
    • Organizer
      9th World Congress of Biomechanics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 壁せん断応力-法線方向動圧組み合わせ環境が血管内皮細胞に及ぼす影響.2022

    • Author(s)
      髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉.
    • Organizer
      第45回日本バイオレオロジー学会年会
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 弁形態分析に基づく大動脈二尖弁狭窄症例の上行大動脈拡大と治療成績に関する検討2021

    • Author(s)
      木村直行, 堀大治郎, 草処翔, 清水寿和,   野村陽平, 白石学, 川人宏次, 山口敦司
    • Organizer
      第49回日本血管外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] 大動脈二尖弁性狭窄と大動脈三尖弁性狭窄の治療成績とaortic stiffnessに関する検討2021

    • Author(s)
      木村直行, 堀大治郎, 草処翔, 清水寿和, 白石学,川人宏次, 山口敦司
    • Organizer
      第51回日本心臓血管外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] 大動脈二尖弁性狭窄と大動脈三尖弁性狭窄の治療成績とaortic stiffnessに関する検討2021

    • Author(s)
      木村直行, 堀大治郎, 草処翔, 清水寿和, 白石学,川人宏次, 山口敦司
    • Organizer
      第51回日本心臓血管外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 弁形態分析に基づく大動脈二尖弁狭窄症例の上行大動脈拡大と治療成績に関する検討2021

    • Author(s)
      木村直行, 堀大治郎, 草処翔, 清水寿和,   野村陽平, 白石学, 川人宏次, 山口敦司
    • Organizer
      第49回日本血管外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020

    • Author(s)
      沢崎薫 ,堀江悠太,中村匡徳,木村直行,川人宏次,坂元尚哉
    • Organizer
      生体医工学会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] 内皮-平滑筋細胞共培養モデルのMMP産生に対する高壁せん断応力環境の影響2020

    • Author(s)
      坂元尚哉,大山侑樹,中村匡徳,木村直行,川人宏次,山崎雅史,藤江裕道
    • Organizer
      第59回日本生体医工学会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020

    • Author(s)
      沢崎薫,堀江悠太,中村匡徳,木村直行, 川人宏次,坂元尚哉
    • Organizer
      第59回日本生体医工学会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] 衝突噴流が血管内皮細胞間接着に及ぼす影響2020

    • Author(s)
      沢崎 薫,堀江 悠太,中村 匡徳,木村 直行,川人 宏次,坂元 尚哉
    • Organizer
      日本機械学会第33回バイオエンジニアリング講演会
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 衝突噴流が血管内皮細胞間接着に及ぼす影響2020

    • Author(s)
      沢崎 薫,堀江 悠太,中村 匡徳,木村 直行,川人 宏次,坂元 尚哉
    • Organizer
      日本機械学会第33回バイオエンジニアリング講演会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] 内皮-平滑筋細胞共培養モデルのMMP産生に対する高壁せん断応力環境の影響2020

    • Author(s)
      坂元尚哉,大山侑樹,中村匡徳,木村直行,川人宏次,山崎雅史,藤江裕道
    • Organizer
      第59回日本生体医工学会
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020

    • Author(s)
      沢崎薫,堀江悠太,中村匡徳,木村直行, 川人宏次,坂元尚哉
    • Organizer
      第59回日本生体医工学会
    • Data Source
      KAKENHI-PROJECT-20K09154
  • [Presentation] 圧縮コラーゲン組織を用いた共培養モデルに対する 高壁せん断応力の影響2019

    • Author(s)
      大山侑樹, 中村匡徳, 木村直行, 川人宏次, 山崎雅史, 藤江裕道, 坂元尚哉
    • Organizer
      日本機械学会 第 32 回バイオエンジニアリング講演会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] Utility of computational fluid dynamics for thoracic aortic pathology in the era of precision medicine2019

    • Author(s)
      NAOYUKI KIMURA, KOKI KAWAHITO, DAJIRO HORI, KOICHI YURI, ATSUSHI YAMAGUCHI, YUUKI OHYAMA, NAOYA SAKAMOTO, MASANORI NAKAMURA
    • Organizer
      第83回 日本循環器病学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] 血管内皮細胞の遊走および剥離に対する衝突流れの場の影響2018

    • Author(s)
      堀江悠太, 大山侑樹, 中村匡徳, 木村直行, 川人宏次, 坂元尚哉
    • Organizer
      日本機械学会 第31回バイオエンジニアリング講演会
    • Data Source
      KAKENHI-PROJECT-17K10763
  • [Presentation] Patient-specific evaluation of hemodynamics in bicuspid aortopathy by means of magnetic resonance imaging based computational fluid dynamics simulation.2016

    • Author(s)
      5.Kimura N, Kawahito K, Komiya K, Numata N, Yamaguchi A, Misawa Y, Nakamura M, Adachi H.
    • Organizer
      AATS Aortic Symposium 2016
    • Place of Presentation
      New York
    • Year and Date
      2016-05-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462117
  • 1.  KIMURA Naoyuki (20382898)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 25 results
  • 2.  中村 匡徳 (20448046)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 20 results
  • 3.  NAKAE Susumu (60450409)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  Matsumoto Kenji (60181765)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  山口 敦司 (50265287)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  吉崎 隆道 (20743115)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  Kario Kazuomi (60285773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Futamura Kyoko (60596956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ITOH Satoshi (30382881)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  星出 聡 (90326851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  新保 昌久 (70406049)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  石川 鎮清 (70306140)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  河野 健 (10327330)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  甲谷 友幸 (00458291)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  小形 幸代 (10448847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  小古山 由佳子 (80742030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  江口 和男 (80364503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  三沢 吉雄 (90209742)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  市田 勝 (30306146)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  池本 智一 (10458284)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  石川 譲治 (90382879)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  坂元 尚哉 (20361115)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 23.  相澤 啓 (50398517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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