Kawahito Koji 川人宏次

… Alternative Names

KAWAHITO KOJI 川人宏次

川人宏次カワヒトコウジ

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Researcher Number	90281740
Other IDs
Affiliation (Current)	2022: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2021: 自治医科大学, 医学部, 教授 1998 – 1999: 自治医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Cardiovascular surgery / Thoracic surgery / Basic Section 55030:Cardiovascular surgery-related Except Principal Investigator Cardiovascular surgery / Cardiovascular medicine
Keywords	Principal Investigator 数値流体力学 / 大動脈二尖弁 / 壁せん断応力 / 血管内皮細胞 / 血管平滑筋細胞 / MMP / 先天性大動脈二尖弁 / 大動脈瘤 / 体外循環 / アポトーシス … More / 心臓手術 / リンパ球 / PCPS / 大動脈弁二尖弁 / 上行大動脈瘤 / 数値流体計算 / 壁剪断応力 / 網羅的遺伝子解析 / 先天性大動脈2尖弁 / 遺伝子解析 / シェアストレス / 胸部大動脈瘤 / 剪断応力 / 共培養モデル / 遺伝子発現解析 / 細胞間接着分子 / 数値流体力学計算 / 胸部大動脈拡大 / 遺伝子 / 内皮細動－平滑筋細胞共培養モデル … More Except Principal Investigator 夜間血圧 / スリープサージ / トリガー血圧計 / IT家庭血圧モニタリング / 基底血圧 / 夜間高血圧 / 大動脈二尖弁 / 大動脈拡大 / 二尖弁化 / ミニブタ / 胸部大動脈拡大 / 大動脈二尖弁化 / 数値流体力学 / せん断応力 / 大型血管炎 / 大動脈炎モデルマウス / IL-25 / IL-1受容体アンタゴニスト欠損マウス / 大動脈炎 / 血管炎モデルマウス / IL-33 / 血管炎マウスモデル / 大血管外科学 / 大動脈炎症候群 Less

Influence of shear stress on human aortic endothelial cell/smooth muscle cell interaction in bicuspid aortic valve aortopathyPrincipal Investigator
- Principal Investigator
  
  川人宏次
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Jichi Medical University
Characterization of wall shear stress sensitive genes in bicuspid aortic valve aortopathyPrincipal Investigator
- Principal Investigator
  
  Koji Kawahito
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice
- Principal Investigator
  
  ITOH Satoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
Bicuspidalization of the native tricuspid aortic valve using a miniature pig
- Principal Investigator
  
  KIMURA Naoyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
Research and development of IT multi-trigger nocturnal home blood pressure monitoring system and clinical study
- Principal Investigator
  
  Kario Kazuomi
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Jichi Medical University
Patient-specific assessment of hemodynamics by computational fluid dynamics and gene expression profiling in patients with bicuspid aortopathy.Principal Investigator
- Principal Investigator
  
  KAWAHITO KOJI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Jichi Medical University
体外循環時のリンパ球減少におけるアポトーシスの関与Principal Investigator
- Principal Investigator
  
  川人宏次
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Thoracic surgery
- Research Institution
  Jichi Medical University

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] A Compressed Collagen Construct for Studying Endothelial-Smooth Muscle Cell Interaction under High Shear Stress2022
- Author(s)
  Yuya Hiroshima, Yuki Oyama, Kaoru Sawasaki, Masanori Nakamura, Naoyuki Kimura, Koji Kawahito, Hiromichi Fujie, Naoya Sakamoto
- Journal Title
  
  Annals of Biomedical Engineering
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09154
[Journal Article] Compressed Collagen Construct for Studying Endothelial Smooth Muscle Cell Interaction Under High Shear Stress2022
- Author(s)
  Hiroshima Y, Oyama Y, Sawasaki K, Nakamura M, Kimura N, Kawahito K, Fujie H
- Journal Title
  
  Ann Biomed Eng.
  
  Volume: -
- DOI
  10.1007/s10439-022-02972-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10763
[Journal Article] Influence of residual primary entry following the tear-oriented strategy for acute type A aortic dissection2021
- Author(s)
  Kawahito K, Aizawa K, Kimura N, Yamaguchi A, Adachi H
- Journal Title
  
  Euro J Cardiothorac Surg
  
  Volume: -
- DOI
  10.1093/ejcts/ezab456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09154
[Journal Article] Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with bicuspid aortopathy2017
- Author(s)
  Kimura N, Nakamura M, Komiya K, Nishi S, Yamaguchi A, Tanaka O, Misawa Y, Adachi H, Kawahito K.
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: 153
- DOI
  10.1016/j.jtcvs.2016.12.033
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462117
[Journal Article] Blood flow competition after aortic valve bypass: an evaluation using computational fluid dynamics2017
- Author(s)
  Kawahito Koji、Kimura Naoyuki、Komiya Kenji、Nakamura Masanori、Misawa Yoshio
- Journal Title
  
  Interact Cardiovasc Thorac Surg
  
  Volume: 24
- DOI
  10.1093/icvts/ivw428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462117
[Presentation] 高壁せん断応力を負荷した共培養血管モデルにおける平滑筋細胞の表現型2022
- Author(s)
  沢崎薫、中村匡徳、木村直行、川人宏次、藤江裕道、坂元尚哉
- Organizer
  日本機械学会 2022年度年次大会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 衝突噴流に伴う力学刺激の組み合わせ環境が血管内皮細胞に及ぼす影響2022
- Author(s)
  髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉
- Organizer
  第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 衝突噴流に伴う力学刺激の組み合わせ環境が血管内皮細胞に及ぼす影響2022
- Author(s)
  髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉
- Organizer
  第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] Study on Effect of Extreme Shear Condition on Endothelial Cell and Smooth muscle Cell Functions using Compressed Collagen Construct.2022
- Author(s)
  1．Sakamoto N, Oyama Y, Sawasaki K, Hiroshima Y, Nakamura M, Kimura N, Kawahito K, Fujie H
- Organizer
  9th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 壁せん断応力-法線方向動圧組み合わせ環境が血管内皮細胞に及ぼす影響．2022
- Author(s)
  髙橋幸慈、沢崎薫、中村匡徳、木村直行、川人宏次、坂元尚哉．
- Organizer
  第45回日本バイオレオロジー学会年会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 弁形態分析に基づく大動脈二尖弁狭窄症例の上行大動脈拡大と治療成績に関する検討2021
- Author(s)
  木村直行,　堀大治郎, 草処翔,　清水寿和, 　　野村陽平,　白石学,　川人宏次, 山口敦司
- Organizer
  第49回日本血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 大動脈二尖弁性狭窄と大動脈三尖弁性狭窄の治療成績とaortic stiffnessに関する検討2021
- Author(s)
  木村直行, 堀大治郎, 草処翔, 清水寿和, 白石学,川人宏次, 山口敦司
- Organizer
  第51回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 大動脈二尖弁性狭窄と大動脈三尖弁性狭窄の治療成績とaortic stiffnessに関する検討2021
- Author(s)
  木村直行, 堀大治郎, 草処翔, 清水寿和, 白石学,川人宏次, 山口敦司
- Organizer
  第51回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 弁形態分析に基づく大動脈二尖弁狭窄症例の上行大動脈拡大と治療成績に関する検討2021
- Author(s)
  木村直行,　堀大治郎, 草処翔,　清水寿和, 　　野村陽平,　白石学,　川人宏次, 山口敦司
- Organizer
  第49回日本血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，川人宏次，坂元尚哉
- Organizer
  生体医工学会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 内皮-平滑筋細胞共培養モデルのMMP産生に対する高壁せん断応力環境の影響2020
- Author(s)
  坂元尚哉，大山侑樹，中村匡徳，木村直行，川人宏次，山崎雅史，藤江裕道
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，　川人宏次，坂元尚哉
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 衝突噴流が血管内皮細胞間接着に及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，川人宏次，坂元尚哉
- Organizer
  日本機械学会第33回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 衝突噴流が血管内皮細胞間接着に及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，川人宏次，坂元尚哉
- Organizer
  日本機械学会第33回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 内皮-平滑筋細胞共培養モデルのMMP産生に対する高壁せん断応力環境の影響2020
- Author(s)
  坂元尚哉，大山侑樹，中村匡徳，木村直行，川人宏次，山崎雅史，藤江裕道
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 衝突噴流環境が血管内皮細胞へ及ぼす影響2020
- Author(s)
  沢崎薫，堀江悠太，中村匡徳，木村直行，　川人宏次，坂元尚哉
- Organizer
  第59回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-20K09154
[Presentation] 圧縮コラーゲン組織を用いた共培養モデルに対する高壁せん断応力の影響2019
- Author(s)
  大山侑樹, 中村匡徳, 木村直行, 川人宏次, 山崎雅史, 藤江裕道, 坂元尚哉
- Organizer
  日本機械学会第 32 回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] Utility of computational fluid dynamics for thoracic aortic pathology in the era of precision medicine2019
- Author(s)
  NAOYUKI KIMURA, KOKI KAWAHITO, DAJIRO HORI, KOICHI YURI, ATSUSHI YAMAGUCHI, YUUKI OHYAMA, NAOYA SAKAMOTO, MASANORI NAKAMURA
- Organizer
  第83回日本循環器病学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] 血管内皮細胞の遊走および剥離に対する衝突流れの場の影響2018
- Author(s)
  堀江悠太, 大山侑樹, 中村匡徳, 木村直行, 川人宏次, 坂元尚哉
- Organizer
  日本機械学会第31回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-17K10763
[Presentation] Patient-specific evaluation of hemodynamics in bicuspid aortopathy by means of magnetic resonance imaging based computational fluid dynamics simulation.2016
- Author(s)
  ５．Kimura N, Kawahito K, Komiya K, Numata N, Yamaguchi A, Misawa Y, Nakamura M, Adachi H.
- Organizer
  AATS Aortic Symposium 2016
- Place of Presentation
  New York
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462117

1. KIMURA Naoyuki (20382898)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
2. 中村匡徳 (20448046)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
3. NAKAE Susumu (60450409)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. Matsumoto Kenji (60181765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 山口敦司 (50265287)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 吉崎隆道 (20743115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Kario Kazuomi (60285773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Futamura Kyoko (60596956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ITOH Satoshi (30382881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 星出聡 (90326851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 新保昌久 (70406049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 石川鎮清 (70306140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 河野健 (10327330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 甲谷友幸 (00458291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小形幸代 (10448847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 小古山由佳子 (80742030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 江口和男 (80364503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 三沢吉雄 (90209742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 市田勝 (30306146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 池本智一 (10458284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 石川譲治 (90382879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 坂元尚哉 (20361115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
23. 相澤啓 (50398517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kawahito Koji 川人 宏次

KAWAHITO KOJI 川人 宏次

川人 宏次 カワヒト コウジ

Research Projects

Research Products

Co-Researchers

Influence of shear stress on human aortic endothelial cell/smooth muscle cell interaction in bicuspid aortic valve aortopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characterization of wall shear stress sensitive genes in bicuspid aortic valve aortopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bicuspidalization of the native tricuspid aortic valve using a miniature pig

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research and development of IT multi-trigger nocturnal home blood pressure monitoring system and clinical study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Patient-specific assessment of hemodynamics by computational fluid dynamics and gene expression profiling in patients with bicuspid aortopathy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

体外循環時のリンパ球減少におけるアポトーシスの関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A Compressed Collagen Construct for Studying Endothelial-Smooth Muscle Cell Interaction under High Shear Stress2022

Author(s)

Journal Title

Data Source

[Journal Article] Compressed Collagen Construct for Studying Endothelial Smooth Muscle Cell Interaction Under High Shear Stress2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Influence of residual primary entry following the tear-oriented strategy for acute type A aortic dissection2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with bicuspid aortopathy2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blood flow competition after aortic valve bypass: an evaluation using computational fluid dynamics2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 高壁せん断応力を負荷した共培養血管モデルにおける平滑筋細胞の表現型2022

Author(s)

Organizer

Data Source

[Presentation] 衝突噴流に伴う力学刺激の組み合わせ環境が血管内皮細胞に及ぼす影響2022

Author(s)

Organizer

Data Source

Kawahito Koji 川人宏次

KAWAHITO KOJI 川人宏次

川人宏次カワヒトコウジ

[Presentation] 圧縮コラーゲン組織を用いた共培養モデルに対する高壁せん断応力の影響2019