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OKUDA Shujiro  奥田 修二郎

ORCIDConnect your ORCID iD *help
Researcher Number 00512310
Other IDs
Affiliation (Current) 2025: 新潟大学, 医歯学系, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 新潟大学, 医歯学系, 教授
2014 – 2020: 新潟大学, 医歯学系, 准教授
2016: 新潟大学, 大学院医歯学総合研究科, 准教授
2014: 新潟大学, 大学院医歯学総合研究科, 准教授
2008 – 2010: Ritsumeikan University, 生命科学部, 助教
2009: 立命館大, 生命科学部, 助教
Review Section/Research Field
Principal Investigator
Medium-sized Section 62:Applied informatics and related fields / ゲノム情報科学 / Life / Health / Medical informatics
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 57:Oral science and related fields / Basic Section 53020:Cardiology-related / Basic Section 52040:Radiological sciences-related / Basic Section 49020:Human pathology-related … More / Medium-sized Section 52:General internal medicine and related fields / Transformative Research Areas, Section (III) / Basic Section 37030:Chemical biology-related / Basic Section 56070:Plastic and reconstructive surgery-related / Basic Section 56060:Ophthalmology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 48010:Anatomy-related / Basic Section 38030:Applied biochemistry-related / Basic Section 46010:Neuroscience-general-related / Digestive surgery / Oral Science and related fields / Bacteriology (including mycology) / Human pathology / Brain biometrics / Aquatic life science Less
Keywords
Principal Investigator
メタゲノム / データベース / 環境 / 質量分析 / NMF / メタプロテオーム / 精密医療 / がんゲノム / 共生細菌叢 / 種間相互作用 / マイクロバイオーム / 腸内細菌 … More
Except Principal Investigator
… More スフィンゴシン-1-リン酸 / 脂質メディエーター / 人工知能 / 乳癌 / 胃癌 / バイオインフォマティクス / 治療 / スフィンゴシン-1-リン酸 / ゲノム解析 / 高次元データ解析 / 消化器癌 / 炎症 / 細菌叢 / 癌遺伝子異常 / マイクロサテライト不安定性 / 免疫組織化学染色 / HER2 / ERBB2 / 腸内細菌 / 薬剤耐性 / 発癌メカニズム / ゲノム / 歯周病治療学 / 歯周病 / 歯周炎 / 心不全 / 心筋生検 / 放射線・病理画像診断 / バーチャルスライド / 病理画像 / CT画像 / Radiomics / 腫瘍遺伝子変異量 / テクスチャ解析 / 肺癌 / 創薬 / マウスモデル / ドラッグデリバリー / ドラッグデリバリーシステム / 治療開発 / 難治性腫瘍 / 腫瘍微小環境 / 悪性リンパ腫 / リンパ腫 / 宿主免疫細胞 / 難治性リンパ腫 / ヘテロプラスミー / シングルセル / マルチオミックス解析 / ヘテロプラスミー率 / 心筋症 / シングルセル解析 / メタボローム解析 / ミトコンドリアDNA / オミックス解析 / ミトコンドリア病 / 安定同位体標識 / 質量分析 / タンパク質寿命 / プロテオミクス / 抗体 / ライブセルイメージング / AI / 膜透過ペプチド / ゲ ノム解析 / 16S rRNA遺伝子解析 / DNA付加体 / 変異シグネチャー解析 / 腫瘍内細菌叢 / 評価法 / 画像解析 / 顔面神経麻痺 / QOL(quality of life) / AI(人工知能) / 緑内障 / OCTアンギオグラフィー(OCTA) / 光干渉断層計(OCT) / コントラスト感度 / 両眼視野 / Virtual reality(VR) / Artificial intelligence / Quality of life(QOL) / 緑内障性視神経症 / Whole slide imaging / がん遺伝子パネル検査 / 免疫組織化学 / 遺伝子ネットワーク / 細胞追跡 / 細胞系譜 / 幹細胞 / 歯根膜 / トリプルネガティブ / TP53 / mutational signature / 遺伝子パネル検査 / 塩基置換 / 固形癌 / ターゲット遺伝子パネル検査 / 変異シグネチャー / 化学放射線療法 / 臨床的完全奏効 / 腫瘍変異負荷量 / pathway解析 / 遺伝子変異 / サーベイランス / Watch and Wait / 術前化学放射線療法 / 直腸癌 / 高次元データ解析システム / 腫瘍変異負荷 / ゲノム高次元データ解析 / 深層学習 / リンパ洞フィルター / 細胞間相互作用 / 免疫応答 / 組織マクロファージ / 間質ストローマ細胞 / 抗体産生 / T細胞応答 / リンパ液フィルター / ストローマ細胞 / マクロファージ / リンパ管内皮細胞 / リンパ洞 / リンパ節 / 共生・共進化 / 転写因子 / 代謝物 / スルホグルコシダーゼ / 糖鎖 / ムチン糖鎖 / 母乳オリゴ糖 / 酵素機能解析 / ビフィズス菌 / ヒト母乳オリゴ糖 / ムチンO-グリカン / 共生 / 樹状突起形成 / 視覚経験 / ホメオ蛋白質 / 神経回路形成 / 視覚野 / 樹状突起 / 細胞骨格因子 / 視覚弁別課題 / 臨界期 / 発達障害 / 抑制性ニューロン / 腸内細菌叢 / 回腸嚢炎 / 潰瘍性大腸炎 / スフィンゴシン‐1-リン酸 / 腫瘍免疫微小環境 / チャンバーモデル / 抗炎症好中球 / 貪食好中球 / 免疫 / 抗炎症 / 白血球 / 骨免疫 / 骨吸収 / 実験的歯周炎 / 歯周炎マウスモデル / 好中球 / 炎症性サイトカイン / 抗炎症性サイトカイン / 好中球サブセット / 体液 / バイオマーカー / 薬物療法 / 伝播経路 / 消化器 / ヒト共生細菌叢 / DNAミスマッチ修復機構 / tumor mutation burden / nivolumab / PD-L1 / ミスマッチ修復タンパク質 / HER2陽性胃癌 / FISH / 癌遺伝子パネル / trastuzumab / 癌遺伝子解析パネル / 抗HER2療法 / HER2陽性 / 歯周病原細菌 / 口ー腸連関 / オーミクス解析 / 口腔細菌 / トリプルネガティブ乳癌 / 癌代謝 / スフィンゴシンキナーゼ1型 / 発癌 / 腫瘍内リンパ球浸潤 / 低分化胞巣 / TMB-H / SMAD4 / SMAD2 / ACVR2A / TGFBR2 / TGF-β / 大腸癌 / 薬剤感受性 / ゲノム分類 / NGS / 新臨床分類 / がんゲノム / Precision medicine / Precision Medicine / 癌ゲノム解析 / 歯周治療学 / Keystone細菌 / 精密医療 / 菌叢解析 / メタゲノム解析 / ディープラーニング / クリティカルパス / デジタルプラットフォーム / 歯周病治療 / 微生物 / 乳酸デヒドロゲナーゼ / 抗生物質 / 感染症 / マイクロアレイ / 休止細菌 / 大腸菌 / 病理学 / 浸潤 / 転移 / PODXL1 / TRA-1-60 / 膵がん / 脳・神経 / 側頭葉 / マカクザル / 信号伝搬 / 前頭葉 / 視覚 / 皮質脳波 / 共生微生物 / 生物活性物質 / メタボロミクス / 海洋天然物 Less
  • Research Projects

    (39 results)
  • Research Products

    (85 results)
  • Co-Researchers

    (116 People)
  •  Development of a "live cell imaging system" using membrane-penetrating peptides and AI

    • Principal Investigator
      奥田 明子 (田所明子)
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      Niigata University
  •  精密メタプロテオーム解析を実現する高度情報科学基盤の構築Principal Investigator

    • Principal Investigator
      奥田 修二郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 62:Applied informatics and related fields
    • Research Institution
      Niigata University
  •  Large-scale measurement techniques for protein lifetime and principles of lifetime control

    • Principal Investigator
      石濱 泰
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Kyoto University
  •  Establishment of multi-layered omics analysis for mitochondrial disease patients

    • Principal Investigator
      岡崎 康司
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University
  •  放射線・病理画像テクスチャ解析を用いた肺癌の腫瘍遺伝子変異量予測モデルの開発

    • Principal Investigator
      山崎 元彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Niigata University
  •  人工知能による心筋生検の読影を用いた重症心不全の統合的予後推測法の確立

    • Principal Investigator
      猪又 孝元
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Niigata University
  •  不均一性の強い胃癌のHER2関連遺伝子異常を高精度に同定可能とする人工知能の開発

    • Principal Investigator
      臼井 賢司
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Niigata University
  •  緑内障による構造と機能の変化はどのように患者のQOLを障害するのか?

    • Principal Investigator
      福地 健郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Niigata University
  •  人工知能を用いた顔面神経麻痺の客観的主観評価システムの確立

    • Principal Investigator
      松田 健
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Niigata University
  •  腫瘍内細菌叢が引き起こす癌遺伝子異常の同定と変異シグネチャー解析による要因の解明

    • Principal Investigator
      若井 俊文
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  乳癌における脂質メディエーターを標的とする薬物送達システムを用いた新規治療の開発

    • Principal Investigator
      永橋 昌幸
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Hyogo Medical University
  •  Enzymatic insight into the microbiota formation in infant guts

    • Principal Investigator
      Katayama Takane
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38030:Applied biochemistry-related
    • Research Institution
      Kyoto University
  •  Molecular/cellular basis of lymphatic sinus filter in lymph node

    • Principal Investigator
      Katakai Tomoya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Niigata University
  •  Development of Artificial Intelligence by Deep Learning Based on Genomic High-Dimensional Data Analysis System for Gastrointestinal Cancer

    • Principal Investigator
      WAKAI TOSHIFUMI
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Establishment of a new surveillance method for clinical complete response after chemoradiotherapy in patients with rectal cancer

    • Principal Investigator
      Shimada Yoshifumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Establishment of classification for base substitution pattern and assessment for clinical implication of mutational signature in solid tumors

    • Principal Investigator
      Hirose Yuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  トリプルネガティブ乳癌におけるTP53と脂質分子の相補的な細胞制御機構の解明

    • Principal Investigator
      永橋 昌幸
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Hyogo Medical University
  •  Elucidation of stem cell differentiation mechanism by genetic cell tracing and gene network analysis

    • Principal Investigator
      加来 賢
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Niigata University
  •  難治性リンパ腫の免疫回避機構の解明と新しい治療法の開発

    • Principal Investigator
      高田 尚良
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Niigata University
  •  Pathogenesis of pouchitis after ileal pouch anal anastomosis for ulcerative colitis: Analysis of intestinal microbiota and lipid mediators.

    • Principal Investigator
      Kameyama Hitoshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Clinical significance of comprehensive genomic analysis in HER2 positive gastric cancer

    • Principal Investigator
      Usui Kenji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Verification of microsatellite instability status evaluated by cancer gene panel testing and clinical significance in the drug treatment for gastric cancer

    • Principal Investigator
      Hanyu Takaaki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Elucidation of the interaction between human commensal bacterial flora and host genetic alterations in the digestive tract

    • Principal Investigator
      Wakai Toshifumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  Challenges to the identification of neutrophil subsets involved in the development and remission of inflammation

    • Principal Investigator
      Maekawa Tomoki
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Niigata University
  •  The role of lipid mediator in the tumor immune microenvironment of breast cancer and its therapeutic application

    • Principal Investigator
      Nagahashi Masayuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Hyogo Medical University
      Niigata University
  •  Experience-dependent mechanisms for morphological and functional specification of cortical interneurons

    • Principal Investigator
      Sugiyama Sayaka
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 46010:Neuroscience-general-related
    • Research Institution
      Niigata University
  •  The new classification of colorectal cancer focusing on differences of molecular mechanisms in TGF-b signal pathway

    • Principal Investigator
      Shimada Yoshifumi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Mechanisms of cancer metabolism and drug resistance regulated by S1P in triple negative breast cancer

    • Principal Investigator
      Nagahashi Masayuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  Elucidation of oral-gut association based on Elucidation of oral-gut association based on multi-omics analyzes

    • Principal Investigator
      Yamazaki Kazuhisa
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Niigata University
  •  High-dimensional data analysis platform realizing cancer genome medicinePrincipal Investigator

    • Principal Investigator
      Okuda Shujiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 62:Applied informatics and related fields
    • Research Institution
      Niigata University
  •  Establishment and development of metagenomics-based priodontitis diagnostic platform

    • Principal Investigator
      Maekawa Tomoki
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Oral Science and related fields
    • Research Institution
      Niigata University
  •  New classification of gastric cancer based on genome analysis for precision medicine

    • Principal Investigator
      YOSHIDA KAZUHIRO
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Gifu University
  •  Is the iPS marker "TRA-1-60" an indicator of cancer intractability against therapeutics?

    • Principal Investigator
      Kondo Eisaku
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Niigata University
  •  Molecular mechanism analysis of dormant cells causing refractory nature of bacterial infections

    • Principal Investigator
      TSUNEDA Satoshi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      Waseda University
  •  Profiling of disease factors in human microbiomePrincipal Investigator

    • Principal Investigator
      Okuda Shujiro
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Life / Health / Medical informatics
    • Research Institution
      Niigata University
  •  Neural mechanisms of visual communications revealed with electrocorticography.

    • Principal Investigator
      Hasegawa Isao
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Brain biometrics
    • Research Institution
      Niigata University
  •  Sponge-metabolomics for the discovery of new bioactive natural products

    • Principal Investigator
      TAKADA Kentaro
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Aquatic life science
    • Research Institution
      The University of Tokyo
  •  Analysis for functional diversity of environmental genomesPrincipal Investigator

    • Principal Investigator
      OKUDA Shujiro
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      ゲノム情報科学
    • Research Institution
      Ritsumeikan University
  •  ゲノムの多様性と環境との相互作用の解析Principal Investigator

    • Principal Investigator
      奥田 修二郎
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      ゲノム情報科学
    • Research Institution
      Ritsumeikan University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2011 2010 2009

All Journal Article Presentation Patent

  • [Journal Article] Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients2023

    • Author(s)
      Nagahashi M, Ling Y, Toshikawa C, Hayashida T, Kitagawa Y, Futamura M, Kuwayama T, Nakamura S, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Tsuchida J, Moro K, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Miyoshi Y, Takabe K, Okuda S, Wakai T.
    • Journal Title

      Breast Cancer

      Volume: - Issue: 4 Pages: 584-595

    • DOI

      10.1007/s12282-023-01449-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19522, KAKENHI-PROJECT-21K17850
  • [Journal Article] Gene panel testing detects important genetic alterations in ulcerative colitis-associated colorectal neoplasia2022

    • Author(s)
      Shimada Y, Nakano M, Mizuno KI, Yokoyama J, Matsumoto A, Tanaka K, Oyanagi H, Nakano M, Hirose Y, Ichikawa H, Sakata J, Kameyama H, Takii Y, Sugai M, Ling Y, Takeuchi S, Okuda S, Terai S, Ajioka Y, Wakai T.
    • Journal Title

      Oncology Letters

      Volume: 24 Issue: 6 Pages: 442-442

    • DOI

      10.3892/ol.2022.13562

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08750, KAKENHI-PROJECT-21K17850, KAKENHI-PROJECT-20K09003
  • [Journal Article] Differential analysis of microbiomes in mucus and tissues obtained from colorectal cancer patients.2022

    • Author(s)
      Tajima Y, Okuda S, Hanai T, Hiro J, Masumori K, Koide Y, Kamiya T, Cheong Y, Inaguma G, Shimada Y, Wakai T, Takihara H, Akimoto S, Matsuoka H, Uyama I, Suda K.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 18193-18193

    • DOI

      10.1038/s41598-022-21928-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Journal Article] 潰瘍性大腸炎術後回腸嚢炎とスフィンゴシン-1-リン酸の関連2022

    • Author(s)
      亀山仁史、永橋昌幸、田島陽介、小柳英人、廣瀬雄己、中野麻恵、中野雅人、島田能史、竹内志穂、奥田修二郎、若井俊文
    • Journal Title

      新潟医学会雑誌

      Volume: 136 Pages: 219-224

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09074
  • [Journal Article] Unveiling microbiome profiles in human inner body fluids and tumor tissues with pancreatic or biliary tract cancer.2022

    • Author(s)
      Okuda S, Hirose Y, Takihara H, Okuda A, Ling Y, Tajima Y, Shimada Y, Ichikawa H, Takizawa K, Sakata J, Wakai T.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 8766-8766

    • DOI

      10.1038/s41598-022-12658-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19556, KAKENHI-PROJECT-21K17850, KAKENHI-ORGANIZER-21H05107
  • [Journal Article] Histopathological characteristics and artificial intelligence for predicting tumor mutational burden-high colorectal cancer2021

    • Author(s)
      Shimada Yoshifumi、Okuda Shujiro、Watanabe Yu、Tajima Yosuke、Nagahashi Masayuki、Ichikawa Hiroshi、Nakano Masato、Sakata Jun、Takii Yasumasa、Kawasaki Takashi、Homma Kei-ichi、Kamori Tomohiro、Oki Eiji、Ling Yiwei、Takeuchi Shiho、Wakai Toshifumi
    • Journal Title

      Journal of Gastroenterology

      Volume: - Issue: 6 Pages: 547-559

    • DOI

      10.1007/s00535-021-01789-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123, KAKENHI-PROJECT-18K08612, KAKENHI-PROJECT-21H02998, KAKENHI-PROJECT-21K17850
  • [Journal Article] Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer.2021

    • Author(s)
      Okuda S, Shimada Y, Tajima Y, Yuza K, Hirose Y, Ichikawa H, Nagahashi M, Sakata J, Ling Y, Miura N, Sugai M, Watanabe Y, Takeuchi S, Wakai T
    • Journal Title

      Comput Struct Biotechnol J

      Volume: 19 Pages: 3330-3338

    • DOI

      10.1016/j.csbj.2021.05.049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22651, KAKENHI-PROJECT-21K17850
  • [Journal Article] Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer2021

    • Author(s)
      Ikarashi Mayuko、Tsuchida Junko、Nagahashi Masayuki、Takeuchi Shiho、Moro Kazuki、Toshikawa Chie、Abe Shun、Ichikawa Hiroshi、Shimada Yoshifumi、Sakata Jun、Koyama Yu、Sato Nobuaki、Hait Nitai C.、Ling Yiwei、Okuda Shujiro、Takabe Kazuaki、Wakai Toshifumi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 24 Pages: 13367-13367

    • DOI

      10.3390/ijms222413367

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03714, KAKENHI-PROJECT-21K17850
  • [Journal Article] Impact of Local Drug Delivery of Minocycline on the Subgingival Microbiota during Supportive Periodontal Therapy: A Randomized Controlled Pilot Study2020

    • Author(s)
      Miyazawa Haruna、Nakajima Takako、Horimizu Makoto、Okuda Kazuhiro、Sugita Noriko、Yamazaki Kyoko、Li Lu、Hayashi-Okada Yoshiko、Arita Takuya、Nishimoto Misa、Nishida Mieko、Genco Robert、Yamazaki Kazuhisa
    • Journal Title

      Dentistry Journal

      Volume: 8 Issue: 4 Pages: 123-123

    • DOI

      10.3390/dj8040123

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09572, KAKENHI-PROJECT-18H04067
  • [Journal Article] Sphingosine Kinase 1 is Associated With Immune Cell Related Gene Expressions in Human Breast Cancer2020

    • Author(s)
      Junko Tsuchida, Masayuki Nagahashi, Masato Nakajima, Eriko Katsuta, Omar M. Rashid, Qianya Qi, Li Yan, Shujiro Okuda, Kazuaki Takabe, Toshifumi Wakai
    • Journal Title

      Journal of Surgical Research

      Volume: 15 Pages: 645-656

    • DOI

      10.1016/j.jss.2020.06.057

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18049, KAKENHI-PROJECT-19H03714
  • [Journal Article] Genetic profiling for diffuse type and genomically stable subtypes in gastric cancer2020

    • Author(s)
      Ling Yiwei、Watanabe Yu、Nagahashi Masayuki、Shimada Yoshifumi、Ichikawa Hiroshi、Wakai Toshifumi、Okuda Shujiro
    • Journal Title

      Computational and Structural Biotechnology Journal

      Volume: 18 Pages: 3301-3308

    • DOI

      10.1016/j.csbj.2020.10.021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123, KAKENHI-PROJECT-19K20397
  • [Journal Article] RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer2020

    • Author(s)
      Matsumoto A, Shimada Y, Nakano M, Oyanagi H, Tajima Y, Nakano M, Kameyama H, Hirose Y, Ichikawa H, Nagahashi M, Nogami H, Maruyama S, Takii Y, Ling Y, Okuda S, Wakai T.
    • Journal Title

      Oncology Reports

      Volume: 43 Pages: 1853-1862

    • DOI

      10.3892/or.2020.7561

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08612, KAKENHI-PROJECT-17K10624, KAKENHI-PROJECT-19K20397
  • [Journal Article] Knowledge base toward understanding actionable alterations and realizing precision oncology.2019

    • Author(s)
      Takeuchi S, Okuda S.
    • Journal Title

      Int J Clin Oncol.

      Volume: 24 Issue: 2 Pages: 123-130

    • DOI

      10.1007/s10147-018-1378-0

    • Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Journal Article] SMAD4 alteration associates with invasive-front pathological markers and poor prognosis in colorectal cancer2019

    • Author(s)
      Oyanagi H, Shimada Y, Nagahashi M, Ichikawa H, Tajima Y, Abe K, Nakano M, Kameyama H, Takii Y, Kawasaki T, Homma KI, Ling Y, Okuda S, Takabe K, Wakai T.
    • Journal Title

      Histopathology

      Volume: 74 Issue: 6 Pages: 873-882

    • DOI

      10.1111/his.13805

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08612
  • [Journal Article] Next generation sequencing-based gene panel tests for the management of solid tumors.2018

    • Author(s)
      Nagahashi M, Shimada Y, Ichikawa H, Kameyama H, Takabe K, Okuda S, Wakai T.
    • Journal Title

      Cancer Sci.

      Volume: 110 Issue: 1 Pages: 6-15

    • DOI

      10.1111/cas.13837

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Journal Article] Novel gene fusions found in cervical cancer.2018

    • Author(s)
      Ling Y, Okuda S.
    • Journal Title

      EBioMedicine

      Volume: 38 Pages: 13-14

    • DOI

      10.1016/j.ebiom.2018.11.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Journal Article] Poly(ADP-ribose) Polymerase Inhibitors Activate the p53 Signaling Pathway in Neural Stem/Progenitor Cells.2017

    • Author(s)
      Okuda, A., Kurokawa, S., Takehashi, M., Maeda, A., Fukuda, K., Kubo, Y., Nogusa, H., Takatani-Nakase, T., Okuda, S., Ueda, K., Tanaka, S.
    • Journal Title

      BMC Neurosci.

      Volume: 18 Issue: 1 Pages: 14-14

    • DOI

      10.1186/s12868-016-0333-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-15K07955, KAKENHI-PROJECT-16K08257
  • [Journal Article] The ProteomeXchange Consortium in 2017: supporting the cultural change in proteomics public data deposition.2017

    • Author(s)
      Deutsch, E. W., Csordas, A., Sun, Z., Jarnuczak, A., Perez-Riverol, Y., Ternent, T., Campbell, D. S., Bernal-Llinares, M., Okuda, S., Kawano, S., Moritz, R. L., Carver, J. J., Wang, M., Ishihama, Y., Bandeira, N., Hermjakob, H., Vizcaíno, J. A.
    • Journal Title

      Nucleic Acids Res.

      Volume: 45 Issue: D1 Pages: D1100-D1106

    • DOI

      10.1093/nar/gkw936

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-16K00416
  • [Journal Article] jPOSTrepo: an international standard data repository for proteomes.2017

    • Author(s)
      Okuda S, Watanabe Y, Moriya Y, Kawano S, Yamamoto T, Matsumoto M, Takami T, Kobayashi D, Araki N, Yoshizawa AC, Tabata T, Sugiyama N, Goto S, Ishihama Y.
    • Journal Title

      Nucleic Acids Res.

      Volume: 45 Issue: D1 Pages: D1107-D1111

    • DOI

      10.1093/nar/gkw1080

    • NAID

      120006353864

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01407, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-16K00416, KAKENHI-PROJECT-16K07118, KAKENHI-PROJECT-16K07198, KAKENHI-PROJECT-15K14383, KAKENHI-PROJECT-16H05440
  • [Journal Article] Rare UNC13B variations and risk of schizophrenia: Whole- exome sequencing in a multiplex family and follow-up resequencing and a case-control study.2016

    • Author(s)
      Egawa J, Hoya S, Watanabe Y, Nunokawa A, Shibuya M, Ikeda M, Inoue E, Okuda S, Kondo K, Saito T, Kaneko N, Muratake T, Igeta H, Iwata N, Someya T
    • Journal Title

      American Journal of medical genetics

      Volume: 14 Issue: 6 Pages: 797-805

    • DOI

      10.1002/ajmg.b.32444

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09802, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-16K15554
  • [Journal Article] Risk factors for neurological worsening and symptomatic watershed infarction in internal carotid artery aneurysm treated by extracranial-intracranial bypass using radial artery graft.2016

    • Author(s)
      Matsukawa H, Tanikawa R, Kamiyama H, Tsuboi T, Noda K, Ota N, Miyata S, Oda J, Takeda R, Tokuda S, Kamada K.
    • Journal Title

      Journal of Neurosurgery

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26242088
  • [Journal Article] Species-function relationships shape ecological properties of the human gut microbiome.2016

    • Author(s)
      Vieira-Silva, S., Falony, G., Lima-Mendez, G., Darzi, Y., Yunta, R., G., Okuda, S., Vandeputte, D., Hildebrand, F., Chaffron, S., Raes, J.
    • Journal Title

      Nat. Microbiol.

      Volume: 1 Issue: 8 Pages: 16088-16088

    • DOI

      10.1038/nmicrobiol.2016.88

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26242088
  • [Journal Article] An adenylyl cyclase with a phosphodiesterase domain in basal plants with a motile sperm system.2016

    • Author(s)
      Kasahara, M., Suetsugu, N., Urano, Y., Yamamoto, C., Ohmori, M., Takada, Y., Okuda, S., Nishiyama, T., Sakayama, H., Kohchi, T., Takahashi, F.
    • Journal Title

      Sci. Rep.

      Volume: 6 Issue: 1 Pages: 39232-39232

    • DOI

      10.1038/srep39232

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-16H05764, KAKENHI-PROJECT-26440156, KAKENHI-PROJECT-15K07185, KAKENHI-PROJECT-15KK0254
  • [Journal Article] p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming2016

    • Author(s)
      Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T et al.
    • Journal Title

      Nature Commun

      Volume: 7 Issue: 1 Pages: 12030-12030

    • DOI

      10.1038/ncomms12030

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-24112009, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-15H04670, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05137, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-16K10565, KAKENHI-PROJECT-15KK0325, KAKENHI-PROJECT-26000014
  • [Journal Article] Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis.2016

    • Author(s)
      Shigehara,Y., Okuda, S., Hayashi,R., Nakai, H., Abe, R., Kurban, M., Shimomura, Y.
    • Journal Title

      Hum. Mol. Genet.

      Volume: 25 Pages: 4484-4493

    • DOI

      10.1093/hmg/ddw277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26242088
  • [Journal Article] Identification of Enzyme Genes Using Chemical Structure Alignments of Substrate-Product Pairs.2016

    • Author(s)
      Moriya, Y., Yamada, T., Okuda, S., Nakagawa, Z., Kotera, M., Tokimatsu, T., Kanehisa, M. & Goto, S.
    • Journal Title

      Journal of Chemical Information and Modeling

      Volume: 56 Issue: 3 Pages: 510-516

    • DOI

      10.1021/acs.jcim.5b00216

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25710016, KAKENHI-PROJECT-26242088
  • [Journal Article] Genomic landscape of colorectal cancer in Japan: Clinical implications of comprehensive genomic sequencing for precision medicine.2016

    • Author(s)
      Nagahashi M, Wakai T, Shimada Y, Ichikawa H, Kameyama H, Kobayashi T, Sakata J, Sato N, Kitagawa Y, Uetake H, Yoshida K, Oki E, Kudo S, Izutsu H, Komada K, Nakada M, Tse J, Russell M, Heyer J, Powers W, Sun R, Ring J. E, Takabe K, Protopopov A, Ling Y, Okuda S, Lyle S.
    • Journal Title

      Genome Medicine

      Volume: 8 Issue: 1 Pages: 136-136

    • DOI

      10.1186/s13073-016-0387-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26700029
  • [Journal Article] GlyTouCan 1.0-The international glycan structure repository.2016

    • Author(s)
      Aoki-Kinoshita K, Aoki N. P, Shinmachi D, Fujita A, Tsuchiya S, Matsubara M, Okuda S, Fujita N, Yamada I, Narimatsu H.
    • Journal Title

      Nucleic Acids Reseach

      Volume: 44 Issue: D1 Pages: D1237-D1242

    • DOI

      10.1093/nar/gkv1041

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26242088
  • [Journal Article] Large-scale analysis of evolutionary histories of phosphorylation motifs in the human genome.2015

    • Author(s)
      Hisayoshi Yoshizaki and Shujiro Okuda
    • Journal Title

      GigaScience

      Volume: 4 Issue: 1 Pages: 21-21

    • DOI

      10.1186/s13742-015-0057-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24770190, KAKENHI-PROJECT-26700029
  • [Journal Article] RNA sequencing revealed numerous polyketide synthase genes in the harmful dinoflagellate Karenia mikimotoi2015

    • Author(s)
      Kimura K, Okuda S, Nakayama K, Shikata T, Takahashi F, Yamaguchi H, Sakamoto S, Yamaguchi M, Tomaru Y
    • Journal Title

      PLOS One

      Volume: 10 Issue: 11 Pages: 0142731-0142731

    • DOI

      10.1371/journal.pone.0142731

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26440156, KAKENHI-PROJECT-26660155, KAKENHI-PROJECT-26242088
  • [Journal Article] Resequencing and Association Analysis of CLN8 with Autism Spectrum Disorder in a Japanese Population.2015

    • Author(s)
      染矢俊幸
    • Journal Title

      PLoS One.

      Volume: 10(12) Issue: 12 Pages: e0144624-e0144624

    • DOI

      10.1371/journal.pone.0144624

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670511, KAKENHI-PROJECT-26860917, KAKENHI-PROJECT-26242088
  • [Journal Article] Novel kinase fusion transcripts found in endometrial cancer.2015

    • Author(s)
      Tamura R, Yoshihara K, Yamawaki K, Suda K, Ishiguro T, Adachi S, Okuda S, Inoue I, Verhaak RG, Enomoto T.
    • Journal Title

      Sci Rep.

      Volume: 5 Issue: 1 Pages: 18657-18657

    • DOI

      10.1038/srep18657

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15598, KAKENHI-PROJECT-15H02373, KAKENHI-PROJECT-26640126, KAKENHI-PROJECT-25293338, KAKENHI-PROJECT-26242088
  • [Journal Article] Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells2015

    • Author(s)
      Takachi T, Takahashi M, Takahashi-Yoshita M, Higuchi M, Obata M, Mishima Y, Okuda S, Tanaka Y, Matsuoka M, Saitoh A, Green PL, Fujii M.
    • Journal Title

      Cance Science

      Volume: 106(4) Issue: 4 Pages: 461-465

    • DOI

      10.1111/cas.12618

    • NAID

      120006844098

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670222, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26461417, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-25340027, KAKENHI-PROJECT-26242088
  • [Journal Article] Elucidation of the evolutionary expansion of phosphorylation signaling networks using comparative phosphomotif analysis.2014

    • Author(s)
      Hisayoshi Yoshizaki and Shujiro Okuda
    • Journal Title

      BMC Genomics

      Volume: 15 Issue: 1 Pages: 546-546

    • DOI

      10.1186/1471-2164-15-546

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24770190, KAKENHI-PROJECT-26242088
  • [Journal Article] GlycoRDF: an ontology to standardize glycomics data in RDF.2014

    • Author(s)
      Ranzinger R, Aoki-Kinoshita KF, Campbell MP, Kawano S, Lutteke T, Okuda S, Shinmachi D, Shikanai T, Sawaki H, Toukach P, Matsubara M, Yamada I, Narimatsu H.
    • Journal Title

      Bioinformatics

      Volume: 31(6) Issue: 6 Pages: 919-25

    • DOI

      10.1093/bioinformatics/btu732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24241073, KAKENHI-PROJECT-26242088
  • [Journal Article] Enhanced Translocation and Growth of <i>Rhodococcus erythropolis</i> PR4 in the Alkane Phase of Aqueous-Alkane Two Phase Cultures Were Mediated by GroEL2 Overexpression2014

    • Author(s)
      H. Takihara, J. Ogihara, T. Yoshida, S. Okuda, M. Nakajima, N. Iwabuchi, M. Sunairi.
    • Journal Title

      Microbes and Environments

      Volume: 29 Issue: 4 Pages: 346-352

    • DOI

      10.1264/jsme2.ME13158

    • NAID

      130004693791

    • ISSN
      1342-6311, 1347-4405
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24310060, KAKENHI-PROJECT-24570252, KAKENHI-PROJECT-26242088
  • [Journal Article] ODB : a database for operon organizations, 2011 update.2011

    • Author(s)
      Shujiro Okuda, Akiyasu C.Yoshizawa
    • Journal Title

      39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21710212
  • [Journal Article] ODB : a database for operon organizations, 2011 update2011

    • Author(s)
      Shujiro Okuda, Akiyasu C.Yoshizawa
    • Journal Title

      Nucleic Acids Research

      Volume: 39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21710212
  • [Patent] 高頻度変異型癌の判別システム、プログラム及び方法2021

    • Inventor(s)
      若井俊文、奥田修二郎、島田能史、井筒 浩、兒玉啓輔
    • Industrial Property Rights Holder
      若井俊文、奥田修二郎、島田能史、井筒 浩、兒玉啓輔
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Patent] SYSTEM, PROGRAM, AND METHOD FOR DETERMINING HYPERMUTATED TUMOR2021

    • Inventor(s)
      若井俊文、奥田修二郎、島田能史
    • Industrial Property Rights Holder
      若井俊文、奥田修二郎、島田能史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2024
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Patent] SYSTEM, PROGRAM, AND METHOD FOR DETERMINING HYPERMUTATED2021

    • Inventor(s)
      若井俊文、奥田修二郎、島田能史、井筒 浩、兒玉啓輔
    • Industrial Property Rights Holder
      若井俊文、奥田修二郎、島田能史、井筒 浩、兒玉啓輔
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] Proteogenome analysis of lung cancer cell lines for comprehensive identification of novel proteoforms2024

    • Author(s)
      谷口優斗、西田紘士、奥田修二郎、石濱泰
    • Organizer
      第7回 京都生体質量分析研究会国際シンポジウム・第521回 生存圏シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23H04924
  • [Presentation] Correlation of mutational signature between whole genome sequencing and gene panel tests in colorectal cancer2023

    • Author(s)
      廣瀬雄己,島田能史,田島陽介,阿部 馨,松本瑛生,大関 瑛,土田純子,諸 和樹,宗岡悠介,市川 寛,竹内志穂,永橋昌幸,坂田 純,奥田修二郎,若井俊文
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08750
  • [Presentation] タンパク質末端ペプチド濃縮法を用いた非小細胞肺がん細胞株のプロテオフォーム解析2023

    • Author(s)
      谷口優斗、西田紘士、奥田修二郎、石濱泰
    • Organizer
      日本プロテオーム学会 2023 年大会
    • Data Source
      KAKENHI-PLANNED-23H04924
  • [Presentation] 緑内障患者の視覚的QOL推定モデルの構築2023

    • Author(s)
      飯川龍、凌一葦、奥田修二郎、赤木忠道、坂上悠太、五十嵐遼子、有松真央、福地健郎
    • Organizer
      第34回日本緑内障学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K09764
  • [Presentation] AIを用いた緑内障患者のQOV推定モデルの構築2023

    • Author(s)
      飯川龍、凌一葦、奥田修二郎、赤木忠道、坂上悠太、五十嵐遼子、有松真央、宮島誠、福地健郎
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09764
  • [Presentation] 大腸癌患者の全ゲノム解析と遺伝子パネル検査における変異シグネチャーの相関性2023

    • Author(s)
      廣瀬 雄己, 島田 能史, 田島 陽介, 安部 馨, 松本 瑛生, 大関 瑛, 土田 純子, 諸 和樹, 宗岡 悠介, 市川 寛, 竹内 志穂, 永橋 昌幸, 坂田 純, 奥田 修二郎, 若井 俊文
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] 緑内障患者のquality of vision(QOV)に影響を与える視野領域の検討2023

    • Author(s)
      飯川龍、凌一葦、奥田修二郎、赤木忠道、坂上悠太、五十嵐遼子、有松真央、福地健郎
    • Organizer
      第12回日本視野画像学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K09764
  • [Presentation] 大腸癌における細菌叢と臨床病理学的因子および予後との関連2023

    • Author(s)
      田島 陽介, 島田 能史, 中野 麻恵, 中野 雅人, 山井 大介, 阿部 馨, 松本 瑛生, 大関 瑛, 宗岡 悠介, 廣瀬 雄己, 臼井 賢司, 石川 博補, 加納 陽介, 三浦 宏平, 市川 寛, 滝沢 一泰, 小林 隆, 坂田 純, 奥田 修二郎, 若井 俊文
    • Organizer
      第123回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] がん細胞のプロテアーゼ制御機構解明に向けたタンパク質ターミノーム解析2023

    • Author(s)
      谷口優斗、西田紘士、奥田修二郎、石濱泰
    • Organizer
      第20回次世代を担う若手のためのフィジカル・ファーマフォーラム(PPF2023)
    • Data Source
      KAKENHI-PLANNED-23H04924
  • [Presentation] ヒトの大腸癌および大腸粘膜に定着した細菌を同定する手法の検討2022

    • Author(s)
      田島陽介、廣純一郎、松岡 宏、花井 恒一、島田能史、奥田修二郎、若井俊文、須田康一
    • Organizer
      第30回日本消化器関連学会週間(JDDW2022)
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] Tumor mutational burden-High大腸癌を予測する人工知能の開発2022

    • Author(s)
      島田能史、奥田修二郎、中野麻恵、松本瑛生、 田島陽介、中野雅人、石川博補、臼井賢司、加納陽介、三浦宏平、市川寛、羽入隆晃、滝沢一泰、石川卓、坂田純、小林隆、野上仁、丸山聡、瀧井康公、若井俊文
    • Organizer
      第122回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] COPY number alterations is an independent prognostic biomarker in triple-negative breast cancer patients2022

    • Author(s)
      Nagahashi M, Ling Y, Toshikawa C, Hayashida T, Kitagawa Y, Futamura M, Kuwayama T, Nakamura S, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Tsuchida J, Moro K, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Miyoshi Y, Takabe K, Okuda S, Wakai T.
    • Organizer
      2022 San Antonio Breast Cancer Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24399
  • [Presentation] Translation-dependent wiring of cortical local circuits in visual cortex2021

    • Author(s)
      Hou X, Ling Y, Sakimura K, Okuda S, and Sugiyama S
    • Organizer
      The 44th Annual Meeting of the Japan Neuroscience Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03322
  • [Presentation] Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer 大腸癌における宿主の遺伝子変異と腫瘍内細菌叢のプロファイリング2021

    • Author(s)
      Toshifumi Wakai, Shujiro Okuda, Yoshifumi Shimada, Yosuke Tajima, Yuki Hirose, Hiroshi Ichikawa, Yiwei Ling, Nobuaki Miura, Mika Sugai, Yu Watanabe, Shiho Takeuchi, Jun Sakata
    • Organizer
      The 32nd Annual Meeting of the Japanese Society for Gastroenterological Carcinogenesis
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22651
  • [Presentation] Targetome profiling of Otx2-eIF4E dependent translation in cortical plasticity2020

    • Author(s)
      Hou X. Ling Y. Sakai A. Okuda S. Sugiyama S.
    • Organizer
      The 43th Annual Meeting of the Japan Neuroscience Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03322
  • [Presentation] Gene panel testing as a clinical application for detecting HER2 alterations in gastric cancer2020

    • Author(s)
      Hiroshi Ichikawa, Kenji Usui, Yoshifumi Shimada, Yusuke Muneoka, Takaaki Hanyu, Yosuke Kano, Takashi Ishikawa, Kohei Miura, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Hiroshi Yabusaki, Satoru Nakagawa, Hitoshi Kameyama, Shujiro Okuda, Toshifumi Wakai
    • Organizer
      15th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09117
  • [Presentation] 病理画像から遺伝子変異を予測する2020

    • Author(s)
      奥田修二郎
    • Organizer
      第9回生命医薬情報学連合大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] 次世代シークエンサーを用いた遺伝子検査とゲノム解析データベース構築2019

    • Author(s)
      永橋昌幸、若井俊文、島田能史、市川寛、羽入隆晃、滝沢一泰、石川卓、坂田純、小林隆、亀山仁史、竹内志穂、奥田修二郎
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] Mutational signatures and clinicopathological relationship extracted from clinical sequence data of 201 cases with colorectal cancer.2019

    • Author(s)
      Takeuchi, S., Ling, Y., Watanabe, Y., Shimada, Y., Wakai, T., Okuda, S.
    • Organizer
      ASHG2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] Precision medicine実現に向けたがんゲノムインフォマティクス2019

    • Author(s)
      奥田修二郎
    • Organizer
      第8回生命医薬情報学連合大会
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] 固形癌における包括的ゲノム解析に基づくPrecision Medicine2019

    • Author(s)
      若井俊文、島田能史、永橋昌幸、市川寛、油座築、根本万里子、中野麻恵、廣瀬雄己、滝沢一泰、坂田純、亀山仁史、小林隆、棗田学、吉原弘祐、奥田修二郎
    • Organizer
      第57回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] Precision medicine を目指すがんゲノムインフォマティクス2019

    • Author(s)
      奥田修二郎
    • Organizer
      JPrOS2019/JES2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] プレシジョンメディスン実現に向けたがんゲノムインフォマティクスとマイクロバイオームへの応用2019

    • Author(s)
      奥田修二郎
    • Organizer
      第61回日本婦人科腫瘍学会・第18回日本婦人科がん分子標的研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] Precision Medicine実現に向けたバイオインフォマティクスの役割2019

    • Author(s)
      奥田修二郎
    • Organizer
      第57回日本癌治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] Genome-wide analysis of mutational impact on post translational modification.2019

    • Author(s)
      Ling, Y., Yoshizaki, H., Okuda, S.
    • Organizer
      ISMB2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] Computational approaches towards understanding human genome, proteome, and proteogenome data2018

    • Author(s)
      Shujiro Okuda
    • Organizer
      2018 Taiwan-Japan Joint Conference for Genomics and Proteogenomics and Annual Retreat of Taiwan Genomics and Genetics Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] Genome-wide analysis of single nucleotide variants on phosphorylation motifs.2018

    • Author(s)
      Yoshizaki, H., Ling Y., Kohno, M., Okuda, S.
    • Organizer
      ASBMB2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] 新潟大学におけるがんゲノムプロジェクト2018

    • Author(s)
      奥田修二郎
    • Organizer
      第22回医療情報学会春季学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] がんゲノム医療を加速するデータ解析システム2018

    • Author(s)
      奥田修二郎、渡辺由、凌一葦、竹内志穂
    • Organizer
      第78回新潟癌治療研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] がんプレシジョンメディシン実現に向けたバイオインフォマティクス:遺伝子変異と治療薬の知識ベース2018

    • Author(s)
      竹内志穂、凌一葦、渡邉由、若井俊文、奥田修二郎
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H04123
  • [Presentation] Tumor mutation burden in triple negative breast cancer patients in Japan2018

    • Author(s)
      Nagahashi M, Ling Y, Hayashida T, Kitagawa Y, Futamura M, Yoshida K, Kuwayama T, Nakamura S, Toshikawa C, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Miyoshi Y, Tsuchida J, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Takabe K, Okuda S, Wakai T
    • Organizer
      2018 American Society of Clinical Oncology Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19576
  • [Presentation] Inference of microbial interactions from human gut meta genome data.2017

    • Author(s)
      Watanabe, Y., Ling, Y. and Okuda, S.
    • Organizer
      ISMB/ECCB2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] 大腸菌のpersister形成を誘導する多様な経路2016

    • Author(s)
      河合祐人,一色理乃,山本尚輝,松本慎也,奥田修二郎,常田聡
    • Organizer
      第31回日本微生物生態学会
    • Place of Presentation
      横須賀
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-15K15134
  • [Presentation] Characterization of a large-scale phosphorylation motifs in human proteome.2016

    • Author(s)
      Ling, Y., Yoshizaki, H. and Okuda, S.
    • Organizer
      HUPO2016
    • Place of Presentation
      Taipei (Taiwan)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] ヒト腸内細菌の代謝反応データベース構築2016

    • Author(s)
      佃直紀、山本希、東光一、入江満、五斗進、奥田修二郎、守屋勇樹、森宙史、黒川顕、山田拓司
    • Organizer
      第10回日本ゲノム微生物学会年会
    • Place of Presentation
      東京工業大学(東京都目黒区)
    • Year and Date
      2016-03-04
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] Proteome-wide human phosphomotif analysis.2016

    • Author(s)
      Okuda, S., Ling, Y., and Yoshizaki, H.
    • Organizer
      ISMB2016
    • Place of Presentation
      Florida (USA)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] ヒトゲノム上のリン酸化モチーフ解析2015

    • Author(s)
      吉崎尚良、奥田修二郎、河野美幸
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] 遺伝子発現から探る休止細菌の分子機構2015

    • Author(s)
      河合祐人,宮川聡史,一色理乃,奥田修二郎,松本慎也,常田聡
    • Organizer
      第29回日本バイオフィルム学会学術集会
    • Place of Presentation
      ホテル竹島(愛知県蒲郡市)
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-15K15134
  • [Presentation] Evolutionary histories of phospho-motifs in the human genome.2015

    • Author(s)
      Shujiro Okuda and Hisayoshi Yoshizaki
    • Organizer
      ISMB2015
    • Place of Presentation
      Conventio Centre Dublin, Dublin, Ireland
    • Year and Date
      2015-07-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] A web tool to infer metagenomic contents from16S rRNA sequences.2014

    • Author(s)
      Shujiro Okuda, and Yu Watanabe
    • Organizer
      ISME2014
    • Place of Presentation
      Coex Convention Center, Seoul, Korea
    • Year and Date
      2014-08-28
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] Large-scale analysis of the evolutionary history of phosphorylation motifs.2014

    • Author(s)
      Shujiro Okuda, and Hisayoshi Yoshizaki
    • Organizer
      ASCB/IFCB2014
    • Place of Presentation
      Pennsylvania Convention Center, Philadelphia, USA
    • Year and Date
      2014-12-09
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] Characterizatoin of protein phosphorylation in the context of evolution.2014

    • Author(s)
      Shujiro Okuda, and Hisayoshi Yoshizaki
    • Organizer
      ISMB2014
    • Place of Presentation
      Hynes Convention Center, Boston, USA
    • Year and Date
      2014-07-13
    • Data Source
      KAKENHI-PROJECT-26700029
  • [Presentation] 環境ゲノムのパスウェイ解析2010

    • Author(s)
      奥田修二郎
    • Organizer
      日本微生物生態学会
    • Place of Presentation
      広島大学(広島県)
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-21710212
  • [Presentation] 環境ゲノムのパスウェイ解析2009

    • Author(s)
      奥田修二郎
    • Organizer
      日本微生物生態学会(第25回大会)
    • Place of Presentation
      広島大学(広島県)
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-21710212
  • 1.  Nagahashi Masayuki (30743918)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 15 results
  • 2.  Shimada Yoshifumi (20706460)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 20 results
  • 3.  Wakai Toshifumi (50372470)
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    # of Collaborated Products: 22 results
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    # of Collaborated Products: 2 results
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    # of Collaborated Products: 2 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 0 results
  • 23.  石川 卓 (70586940)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 24.  小杉 伸一 (90401736)
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
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  • 116.  藤井 雅寛
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