Akita Tenpei 秋田天平

… Alternative Names

AKITA Tenpei 秋田天平

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Researcher Number	00522202
Other IDs	https://orcid.org/0000-0003-4614-4504
Affiliation (Current)	2024: 浜松医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 浜松医科大学, 医学部, 教授 2012 – 2020: 浜松医科大学, 医学部, 准教授 2013: 生理学研究所, 細胞器官研究系, 特任助教 2009 – 2011: National Institute for Physiological Sciences, 細胞器官研究系, 特任助教
Review Section/Research Field	Principal Investigator General physiology / Basic Section 48020:Physiology-related / Mechanobiology Except Principal Investigator Embryonic/Neonatal medicine / Environmental physiology(including physical medicine and nutritional physiology) / General physiology / Biological Sciences
Keywords	Principal Investigator タウリン / 胎生期 / イオンチャネル / WNK3 / 神経前駆細胞 / 電位依存性 / 発達性てんかん性脳症 / 細胞移動 / グルタミン酸 / ATP … More / 細胞間情報伝達 / 活性酸素種 / カルシウムナノドメイン / 細胞容積調節 / 細胞膜電位 / ナトリウムイオン / 大脳基底核原基 / Kv2.1 / カリウムイオン / 生後発達期 / 遺伝子 / 神経科学 / 脳神経疾患 / 生理学 / シナプス可塑性 / Kv4 / CaMKII / Canopy3 / 神経発達障害 / 遺伝子変異 / Gad1 / 自閉症 / 統合失調症 / 脳低形成 / イオンチャネル病 / 招待総説 / 変異導入マウス / てんかん / 細胞膜興奮性 / 電位依存性イオンチャネル / シナプス小胞 / 液胞型プロトンポンプ / 疾患原因遺伝子 / カリウムチャネル / CRISPR-Cas9 / KCNB1 / 神経発火活動 / 錐体神経 / 大脳皮質 / 遺伝子改変マウス / 電位依存性カリウムチャネル / 疾患原因遺伝子変異 / 難治性てんかん / パッチクランプ / 神経発達制御機構 / 細胞内Ca2+シグナリング / 細胞内カルシウムシグナリング / 移動忌避因子 / 移動誘導因子 / GABA / 大脳皮質形成 / ベラルーシ / 国際研究者交流 / 化学伝達物質 / ＡＴＰ / 細胞膜伸展 / 細胞容積感受性アニオンチャネル / Ca^<2+>ナノドメイン / カルシウムイオン / ブラジキニン / アストログリア … More Except Principal Investigator CRH / GABA / ABCF2 / TRPM7 / 塩分負荷 / 低栄養 / GAD / コルチコステロン / KCC2 / WNK / 脳発達 / ストレス / トニックカレント / 細胞移動 / 正中隆起 / メチル化 / 母体ストレス / タウリン / 神経発生 / HPA / タウリントランスポーター / GAD67 / 細胞死 / ATP放出 / 虚血性細胞死 / ネクローシス / アポトーシス / 細胞容積調節 / 酸感受性アニオンチャネル / マキシアニオンチャネル / 容積感受性アニオンチャネル / 分子連関 / ROSセンサー / 容積センサー / メカノセンサー / 蛋白-蛋白相互作用 / モーダルシフト / カチオンチャネル / アニオンチャネル Less

Elucidating regulatory mechanisms for neural precursor development by voltage-dependent ion channelsPrincipal Investigator
- Principal Investigator
  
  秋田天平
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Hamamatsu University School of Medicine
Exploration of the integrated physiological mechanism of membrane excitability regulation through analyses of disease-causing gene mutationsPrincipal Investigator
- Principal Investigator
  
  Akita Tenpei
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hamamatsu University School of Medicine
Exploring the mechanisms for neuronal migration and intercellular communication steered by ion channels in the embryonic brainPrincipal Investigator
- Principal Investigator
  
  Akita Tenpei
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hamamatsu University School of Medicine
Models for developmental disorder induced by interaction of maternal stress and fetal factors
- Principal Investigator
  
  Fukuda Atsuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Hamamatsu University School of Medicine
Multimodal GABA systems responding to environmental stress
- Principal Investigator
  
  Fukuda Atsuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Hamamatsu University School of Medicine
Mechanisms and roles of volume-sensitive anion channel activation mediated by chemical transmitters released in response to cell membrane stretchPrincipal Investigator
- Principal Investigator
  
  AKITA Tenpei
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Mechanobiology
- Research Institution
  Hamamatsu University School of Medicine
  National Institute for Physiological Sciences
Molecular characterization of volume-activated anion channels and elucidation of cell death-survival switching mechanisms
- Principal Investigator
  
  OKADA Yasunobu
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
Research on the activation mechanism of volume-sensitive ion channels in neurons and gliaPrincipal Investigator
- Principal Investigator
  
  AKITA Tenpei
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
Volume-sensor anion channel and mechano-sensor cation channel: Their functional modal shifts and molecular interaction
- Principal Investigator
  
  OKADA Yasunobu
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Physiological Sciences

[Book] "Regulation of neuronal cell migration and cortical development by chloride transporter activities." In Neuronal Chloride Transporters in Health and Disease2020
- Author(s)
  Akita T, Fukuda A
- Total Pages
  650
- Publisher
  Academic Press, Elsevier
- ISBN
  9780128153185
- Data Source
  KAKENHI-PROJECT-17K08534
[Book] 脳科学辞典　「塩素チャネル」2013
- Author(s)
  秋田天平、熊田竜郎、福田敦夫
- Publisher
  脳科学辞典編集委員会
- Data Source
  KAKENHI-PROJECT-23612008
[Book] Patch-clamp techniques : general remarks. In Patch Clamp Techniques : From Beginning to Advanced Protocols, ed. Okada Y, pp 21-41, Springer Protocols Handbooks2012
- Author(s)
  Akita T, Ohara M, Okada Y.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23612008
[Book] "Patch-clamp techniques: general remarks." In Patch Clamp Techniques: From Beginning to Advanced Protocols2012
- Author(s)
  Akita T, Ohara M, Okada Y
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23612008
[Book] 最新パッチクランプ実験技術法（岡田泰伸編）「２章　パッチクランプ法総論」2011
- Author(s)
  岡田泰伸、挾間章博、小原正裕、秋田天平
- Publisher
  吉岡書店
- Data Source
  KAKENHI-PROJECT-23612008
[Book] 最新パッチクランプ実験技術法(岡田泰伸編)「2章パッチクランプ法総論」2011
- Author(s)
  秋田天平、岡田泰伸他
- Publisher
  吉岡書店
- Data Source
  KAKENHI-PROJECT-23612008
[Book] 脳科学辞典「塩素チャネル」
- Author(s)
  秋田天平、熊田竜郎、福田敦夫
- Publisher
  脳科学辞典編集委員会
- Data Source
  KAKENHI-PROJECT-23612008
[Journal Article] A novel de novo KCNB1 variant altering channel characteristics in a patient with periventricular heterotopia, abnormal corpus callosum, and mild seizure outcome2023
- Author(s)
  Hiraide Takuya、Akita Tenpei、Uematsu Kenji、Miyamoto Sachiko、Nakashima Mitsuko、Sasaki Masayuki、Fukuda Atsuo、Kato Mitsuhiro、Saitsu Hirotomo
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 1 Pages: 25-31
- DOI
  10.1038/s10038-022-01090-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08236, KAKENHI-PROJECT-21K06766, KAKENHI-PUBLICLY-21H05687, KAKENHI-PROJECT-20H03641, KAKENHI-PROJECT-21H02661
[Journal Article] Taurine depletion during fetal and postnatal development blunts firing responses of neocortical layer II/III pyramidal neurons.2022
- Author(s)
  Hosoi Y, Akita T, Watanabe M, Ito T, Miyajima H, Fukuda A
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 15: 806798 Pages: 806798-806798
- DOI
  10.3389/fnmol.2022.806798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06924, KAKENHI-PROJECT-21K06766, KAKENHI-PUBLICLY-21H05687, KAKENHI-PROJECT-21H02661
[Journal Article] WNK3 kinase maintains neuronal excitability by reducing inwardly rectifying K+ conductance in layer V pyramidal neurons of mouse medial prefrontal cortex.2022
- Author(s)
  Sinha AS, Wang T, Watanabe M, Hosoi Y, Sohara E, Akita T, Uchida S, Fukuda A
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 15: 856262 Pages: 856262-856262
- DOI
  10.3389/fnmol.2022.856262
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06924, KAKENHI-PROJECT-21K06766, KAKENHI-PUBLICLY-21H05687, KAKENHI-PROJECT-21H02661
[Journal Article] ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H(+)-ATPases is essential for brain development in humans and mice2021
- Author(s)
  Aoto K, Kato M, Akita T, Nakashima M, Mutoh H, Akasaka N, Tohyama J, Nomura Y, Hoshino K, Ago Y, Tanaka R, Epstein O, Ben-Haim R, Heyman E, Miyazaki T, Belal H, Takabayashi S, Ohba C, Takata A, Mizuguchi T, Miyatake S, Miyake N, Fukuda A, Matsumoto N and Saitsu H
- Journal Title
  
  Nat Commun
  
  Volume: 12 Issue: 1 Pages: 2107-2107
- DOI
  10.1038/s41467-021-22389-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-17H04025, KAKENHI-PROJECT-17K00918, KAKENHI-PROJECT-17K08513, KAKENHI-PROJECT-17K08534, KAKENHI-PROJECT-19H01091, KAKENHI-PUBLICLY-21H05687, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-20H03641, KAKENHI-PROJECT-21H02661, KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-20K07243, KAKENHI-PROJECT-20K07423, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08236
[Journal Article] タウリントランスポーター（TauT）欠損の大脳皮質Ⅱ／Ⅲ層錐体神経発火活動への影響について2020
- Author(s)
  秋田天平、細井泰志、伊藤崇志、福田敦夫
- Journal Title
  
  タウリンリサーチ
  
  Volume: 6(1) Pages: 18-19
- NAID
  130008090565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08534
[Journal Article] 細胞内タウリンのプロテインキナーゼCによるリン酸化を介したGABAA受容体膜発現制御2020
- Author(s)
  渡部美穂、細井泰志、秋田天平、伊藤崇志、福田敦夫
- Journal Title
  
  タウリンリサーチ
  
  Volume: 6(1) Pages: 20-22
- NAID
  130008090563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08534
[Journal Article] Intracellular Cl－ dysregulation causing and caused by pathogenic neuronal activity.2020
- Author(s)
  Akita T, Fukuda A
- Journal Title
  
  Pflugers Archiv - European Journal of Physiology
  
  Volume: - Issue: 7 Pages: 977-987
- DOI
  10.1007/s00424-020-02375-4
- NAID
  120007026259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08534, KAKENHI-PROJECT-17H04025, KAKENHI-PROJECT-19H01091
[Journal Article] Biallelic Variants in CNPY3 , Encoding an Endoplasmic Reticulum Chaperone, Cause Early-Onset Epileptic Encephalopathy2018
- Author(s)
  Mutoh Hiroki、Kato Mitsuhiro、Akita Tenpei、Shibata Takuma、Wakamoto Hiroyuki、Ikeda Hiroko、Kitaura Hiroki、Aoto Kazushi、Nakashima Mitsuko、Wang Tianying、Ohba Chihiro、Miyatake Satoko、Miyake Noriko、Kakita Akiyoshi、Miyake Kensuke、Fukuda Atsuo、Matsumoto Naomichi、Saitsu Hirotomo
- Journal Title
  
  The American Journal of Human Genetics
  
  Volume: 102 Issue: 2 Pages: 321-329
- DOI
  10.1016/j.ajhg.2018.01.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08513, KAKENHI-PROJECT-17K08534, KAKENHI-PROJECT-17K19682, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05872, KAKENHI-PROJECT-16H06388, KAKENHI-PROJECT-16H05160, KAKENHI-PROJECT-17H04025, KAKENHI-PROJECT-15K06751, KAKENHI-PROJECT-17K00918, KAKENHI-PROJECT-17K10888, KAKENHI-PROJECT-16H06276
[Journal Article] De novo variants in CAMK2A and CAMK2B cause neurodevelopmental disorders2018
- Author(s)
  Akita Tenpei、Aoto Kazushi、Kato Mitsuhiro、Shiina Masaaki、Mutoh Hiroki、Nakashima Mitsuko、Kuki Ichiro、Okazaki Shin、Magara Shinichi、Shiihara Takashi、Yokochi Kenji、Aiba Kaori、Tohyama Jun、Ohba Chihiro、Miyatake Satoko、Miyake Noriko、Ogata Kazuhiro、Fukuda Atsuo、Matsumoto Naomichi、Saitsu Hirotomo
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: 5 Issue: 3 Pages: 280-296
- DOI
  10.1002/acn3.528
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08513, KAKENHI-PROJECT-17K08534, KAKENHI-PROJECT-17K19682, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05872, KAKENHI-PROJECT-16H05160, KAKENHI-PROJECT-16H05357, KAKENHI-PROJECT-17H04025, KAKENHI-PROJECT-16K09975, KAKENHI-PROJECT-17K00918, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-16H03293
[Journal Article] Alterations of GABAergic Neuron-Associated Extracellular Matrix and Synaptic Responses in Gad1-Heterozygous Mice Subjected to Prenatal Stress2018
- Author(s)
  Wang T, Sinha AS, Akita T, Yanagawa Y, Fukuda A
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 12 Pages: 284-284
- DOI
  10.3389/fncel.2018.00284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08534, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05872, KAKENHI-PROJECT-17H04025, KAKENHI-PROJECT-17K19682
[Journal Article] Impaired neuronal KCC2 function by biallelic SLC12A5 mutations in migrating focal seizures and severe developmental delay.2016
- Author(s)
  Saitsu H, Watanabe M, Akita T, Ohba C, Sugai K, Ong WP, Shiraishi H, Yuasa S, Matsumoto H, Beng KT, Saitoh S, Miyatake S, Nakashima M, Miyake N, Kato M, Fukuda A. and Matsumoto N.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 30072-30072
- DOI
  10.1038/srep30072
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05872, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-16H05160, KAKENHI-PROJECT-16H05357, KAKENHI-PROJECT-26461549, KAKENHI-PROJECT-26670512, KAKENHI-PROJECT-16K08523, KAKENHI-INTERNATIONAL-15K21731
[Journal Article] Ion channels, guidance molecules, intracellular signaling and transcription factors regulating nervous and vascular system development.2015
- Author(s)
  Akita, T., Kumada, T., Yoshihara, S. I., Egea, J., and Yamagishi, S.
- Journal Title
  
  J Physiol Sci.
  
  Volume: 66 Issue: 2 Pages: 175-188
- DOI
  10.1007/s12576-015-0416-1
- NAID
  40020800266
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350594, KAKENHI-PROJECT-26460293, KAKENHI-PROJECT-26670090
[Journal Article] De novo KCNB1 mutations in infantile epilepsy inhibit repetitive neuronal firing.2015
- Author(s)
  Saitsu, H., T. Akita, J. Tohyama, H. Goldberg-Stern, Y. Kobayashi, R. Cohen, M. Kato, C. Ohba, S. Miyatake, Y. Tsurusaki, M. Nakashima, N. Miyake, A. Fukuda, and N. Matsumoto
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 15199-15199
- DOI
  10.1038/srep15199
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461549, KAKENHI-PROJECT-26670512, KAKENHI-PROJECT-15K19660, KAKENHI-PLANNED-15H05872, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-25293052, KAKENHI-PROJECT-25293085, KAKENHI-PROJECT-25293235, KAKENHI-ORGANIZER-15H05871
[Journal Article] Roles of taurine-mediated tonic GABAA receptor activation in radial migration of neurons in the fetal mouse cerebral cortex.2014
- Author(s)
  Furukawa T, Yamada J, Akita T, Matsushima Y, Yanagawa Y, Fukuda A
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 8 Pages: 88-88
- DOI
  10.3389/fncel.2014.00088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23612008, KAKENHI-PROJECT-25293052, KAKENHI-PUBLICLY-26110705, KAKENHI-PROJECT-26670512
[Journal Article] A newly cloned ClC-3 isoform, ClC-3d, as well as ClC-3a mediates Cd^<2+>-sensitive outwardly rectifying anion currents.2014
- Author(s)
  岡田俊昭、秋田天平、佐藤(沼田)かお理、Md. Rafiqul Islam、岡田泰伸
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 33 Issue: 3 Pages: 539-556
- DOI
  10.1159/000358633
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03403, KAKENHI-PROJECT-23612008, KAKENHI-PROJECT-24590291, KAKENHI-PROJECT-25670112, KAKENHI-PROJECT-26293045
[Journal Article] Characteristics and roles of the volume-sensitive outwardly rectifying (VSOR) anion channel in the central nervous system.2014
- Author(s)
  T. Akita & Y. Okada
- Journal Title
  
  Neuroscience
  
  Volume: 275 Pages: 211-231
- DOI
  10.1016/j.neuroscience.2014.06.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670112, KAKENHI-PROJECT-26293045, KAKENHI-PROJECT-26460293
[Journal Article] A newly cloned ClC-3 isoform, ClC-3d, as well as ClC-3a mediates Cd^<2+>-sensitive outwardly rectifying anion currents2014
- Author(s)
  T. Okada, T. Akita, K. Sato-Numata, M.R. Islam, Y. Okada
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 33 Pages: 539-556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Activity-dependent endogenous taurine release facilitates excitatory neurotransmission in the neocortical marginal zone of neonatal rats.2014
- Author(s)
  Qian, T., et al.,
- Journal Title
  
  Front Cell Neurosci.
  
  Volume: 8 Pages: 33-33
- DOI
  10.3389/fncel.2014.00033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500444, KAKENHI-PROJECT-23612008, KAKENHI-PROJECT-24659508, KAKENHI-PROJECT-25282164, KAKENHI-PROJECT-25293052, KAKENHI-PROJECT-26350594
[Journal Article] Modulation of allopregnanolone on excitatory transmitters release from single glutamatergic terminal2013
- Author(s)
  Iwata, S., Wakita, M., Shin, M., Fukuda, A. and Akaike, N.
- Journal Title
  
  Brain Research Bulletin
  
  Volume: 93 Pages: 39-46
- DOI
  10.1016/j.brainresbull.2012.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659508, KAKENHI-PROJECT-25293052
[Journal Article] De Novo Mutations in GNAO1, Encoding a Gαo Subunit of Heterotrimeric G Proteins, Cause Epileptic Encephalopathy.2013
- Author(s)
  Nakamura, K., et al.,
- Journal Title
  
  Am. J. Hum. Genet.
  
  Volume: 93 Issue: 3 Pages: 496-505
- DOI
  10.1016/j.ajhg.2013.07.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500444, KAKENHI-PROJECT-23612008, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118005, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-24249019, KAKENHI-PROJECT-24659508, KAKENHI-PROJECT-25293052, KAKENHI-PROJECT-25293085, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860915
[Journal Article] Early-phase occurrence of K+ and Cl- efflux in addition to Ca2+ mobilization is a prerequisite to apoptosis in HeLa cells.2012
- Author(s)
  出崎克也、前野恵美、佐藤かお理、秋田天平、岡田泰伸
- Journal Title
  
  Apoptosis
  
  Volume: 17 Issue: 8 Pages: 821-831
- DOI
  10.1007/s10495-012-0716-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010, KAKENHI-PROJECT-23591320, KAKENHI-PROJECT-23612008
[Journal Article] Early-phase occurrence of K+ and Cl^- efflux in addition to Ca^<2+> mobilization is a prerequisite to apoptosis in HeLa cells2012
- Author(s)
  K. Dezaki, E. Maeno, K. Sato, T. Akita, Y. Okada
- Journal Title
  
  Apoptosis
  
  Volume: 17 Pages: 821-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca^<2+> nanodomains in mouse astrocytes.2011
- Author(s)
  Akita T, Okada Y
- Journal Title
  
  The Journal of Physiology In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790216
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca^<2+> nanodomains in mouse astrocytes.2011
- Author(s)
  Akita T, Okada Y.
- Journal Title
  
  J Physiol
  
  Volume: 589 Pages: 3909-3927
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca^<2+> nanodomains in mouse astrocytes2011
- Author(s)
  Akita T, Okada Y.
- Journal Title
  
  The Journal of Physiology
  
  Volume: 589(16) Pages: 3909-3927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23612008
[Journal Article] Ca^<2+> nanodomain-mediated component of swelling-induced volume-sensitive outwardly rectifying anion current triggered by autocrine action of ATP in mouse astrocytes2011
- Author(s)
  T. Akita, S.V. Fedorovich, Y. Okada
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 28 Pages: 1181-1190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Ca2+ nanodomain-mediated component of swelling-induced volume-sensitive outwardly rectifying anion current triggered by autocrine action of ATP in mouse astrocytes.2011
- Author(s)
  秋田天平
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 28 Issue: 6 Pages: 1181-1190
- DOI
  10.1159/000335867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010, KAKENHI-PROJECT-23612008
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca2+ nanodomains in mouse astrocytes.2011
- Author(s)
  秋田天平
- Journal Title
  
  Journal of Physiology (London)
  
  Volume: 589 Issue: 16 Pages: 3909-3927
- DOI
  10.1113/jphysiol.2011.208173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010, KAKENHI-PROJECT-23612008
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca^<2+> nanodomains in mouse astrocytes2011
- Author(s)
  T. Akita, Y. Okada
- Journal Title
  
  Journal of Physiology (London)
  
  Volume: 589 Pages: 3909-3927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca^<2+> nanodomains in mouse astrocytes2011
- Author(s)
  T Akita, Y Okada
- Journal Title
  
  J Physiol
  
  Volume: 589 Pages: 3909-3927
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Calcium dependence of the priming, activation and inactivation of ryanodine receptors in frog motor nerve terminals.2010
- Author(s)
  Soga-Sakakibara S, Akita T, et al.
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 32(6) Pages: 948-962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790216
[Journal Article] Bradykinin-induced astrocyte-neuron signaling: glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels.2009
- Author(s)
  Liu H-T, Akita T, Shimizu T, Sabirov RZ, Okada Y.
- Journal Title
  
  J Physiol
  
  Volume: 587 Pages: 2197-209
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Bradykinin-induced astrocyte-neuron signaling : glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels2009
- Author(s)
  H.-T. Liu, T. Akita, T. Shimizu, R.Z. Sabirov, Y. Okada
- Journal Title
  
  Journal of Physiology (London)
  
  Volume: 587 Pages: 2197-2209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Bradykinin-induced astrocyte-neuron signalling : glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels2009
- Author(s)
  Liu HT, Akita T et al.
- Journal Title
  
  The Journal of Physiology 587(10)
  
  Pages: 2197-2209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790216
[Journal Article] Bradykinin-induced astrocyte-neuron signalling : glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels.2009
- Author(s)
  Liu HT, Akita T, Shimizu T, Sabirov RZ, Okada Y
- Journal Title
  
  The Journal of Physiology 587(10)
  
  Pages: 2197-2209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790216
[Journal Article] Bradykinin-induced astrocyte-neuron signaling: glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels2009
- Author(s)
  H.-T. Liu, T. Akita, T. Shimizu, R.Z. Sabirov & Y. Okada
- Journal Title
  
  J. Physiol. (London) 587
  
  Pages: 2197-2209
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Taurine depletion during fetal and postnatal development blunts firing responses of neocortical layer II/III pyramidal neurons.2023
- Author(s)
  Yasushi Hosoi, Tenpei Akita* (*principal presenter), Miho Watanabe, Takashi Ito, Hiroaki Miyajima, Atsuo Fukuda
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K06766
[Presentation] WNK3 kinase maintains neuronal excitability by regulating trafficking of KCC2 and inward rectifying K+ channels in layer V pyramidal neurons.2022
- Author(s)
  Adya Saran Sinha, Tianying Wang, Miho Watanabe, Yasushi Hosoi, Eisei Sohara, Tenpei Akita, Shinichi Uchida, Atsuo Fukuda
- Organizer
  第69回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-21K06766
[Presentation] 胎児期・生後発達期のタウリン枯渇は大脳皮質錐体神経の発火応答を鈍麻させる2021
- Author(s)
  秋田天平、細井泰志、渡部美穂、伊藤崇志、宮嶋裕明、福田敦夫
- Organizer
  第7回国際タウリン研究会日本部会学術集会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] 神経細胞内タウリンによるリン酸化を介したGABAA受容体発現制御機構2021
- Author(s)
  渡部美穂、細井泰志、秋田天平、伊藤崇志、福田敦夫
- Organizer
  第7回国際タウリン研究会日本部会学術集会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] 発達性てんかん性脳症を引き起こすKv2.1 R306C 変異の大脳皮質錐体神経発火活動への影響について2021
- Author(s)
  秋田天平、青戸一司、才津浩智、福田敦夫
- Organizer
  第68回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] 発達性てんかん性脳症を引き起こすKv2.1 R306C 変異の大脳皮質錐体神経発火活動への影響について2021
- Author(s)
  秋田天平、青戸一司、才津浩智、福田敦夫
- Organizer
  第68回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-21K06766
[Presentation] Voltage-sensitive Na+ and K+ current components in interneuron precursors in the medial ganglionic eminence of the embryonic cerebrum.2021
- Author(s)
  Akita T, Fukuda A
- Organizer
  第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] WNK3 kinase maintains basal excitability by regulating inward rectification and intracellular chloride in layer V pyramidal neurons of mouse medial prefrontal cortex.2020
- Author(s)
  Sinha AS, Wang T, Hosoi Y, Sohara E, Akita T, Uchida S, Fukuda A
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] 神経連続発火活動低下を伴うてんかん性脳症発症機序の解明を目指して2020
- Author(s)
  秋田天平、青戸一司、才津浩智、北野勝則、福田敦夫
- Organizer
  第47回日本脳科学会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Two cation current components in GABAergic interneuron precursors in the medial ganglionic eminence of the embryonic brain.2020
- Author(s)
  Akita T, Fukuda A
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] 胎生脳内側基底核原基の神経前駆細胞における２種類の電位依存性陽イオン電流の発見2020
- Author(s)
  秋田天平、福田敦夫
- Organizer
  第67回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Prenatal stress to the Gad1 heterozygotes causes epigenetic changes in neurodevelopment and behavior relating genes and affects their phenotypes.2019
- Author(s)
  Wang T, Sinha AS, Mutoh H, Akita T, Yanagawa Y, Kawai T, Hata K, Fukuda A
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] 胎生期大脳基底核原基の神経前駆細胞に生じる膜電流成分について2019
- Author(s)
  秋田天平、福田敦夫
- Organizer
  第66回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Ca2+ signaling and ion channel activation in embryonic neurons in the medial ganglionic eminence.2019
- Author(s)
  Akita T, Fukuda A
- Organizer
  The 9th Congress of the Federation of Asian and Oceanian Physiological Societies (FAOPS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Static magnetic fields reduce excitability of pyramidal neurons by enhancing membrane Cl－ conductance in the mouse motor cortex.2019
- Author(s)
  Sinha AS, Takamatsu Y, Akita T, Mima T, Fukuda A
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Prenatal stress on Gad1-heterozygotes perturbs development of GABAergic networks affecting behavior.2019
- Author(s)
  Wang T, Sinha AS, Mutoh H, Akita T, Yanagawa Y, Kawai T, Hata K, Fukuda A
- Organizer
  The 9th Congress of the Federation of Asian and Oceanian Physiological Societies (FAOPS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Mechanisms underlying WNK3 kinase mediated regulation of neuronal excitability in prefrontal cortex.2019
- Author(s)
  Sinha AS, Wang T, Hosoi Y, Sohara E, Akita T, Uchida S, Fukuda A
- Organizer
  The 9th Congress of the Federation of Asian and Oceanian Physiological Societies (FAOPS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] De novo CaMKIIalpha/beta mutants causing neurodevelopmental disorders upregulate A-type voltage-dependent K+ currents in hippocampal neurons.2018
- Author(s)
  Akita T, Aoto K, Fukuda A, Matsumoto N, Saitsu H
- Organizer
  The 95th Annual Meeting of The Physiological Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Alterations of GABAergic neuron-associated extracellular matrix and synaptic responses in Gad1-heterozygous mice subjected to prenatal stress.2018
- Author(s)
  Sinha AS, Wang T, Mutoh H, Akita T, Yanagawa Y, Fukuda A
- Organizer
  第65回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Prenatal stress on Gad1-heterozygotes selectively perturbs GABAergic neurogenesis, GABAergic synapse function and behavioral phenotypes.2018
- Author(s)
  Wang T, Sinha AS, Mutoh H, Akita T, Yanagawa Y, Kawai T, Hata K, Fukuda A
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] 胎生期大脳基底核原基の神経前駆細胞内Ca2+オシレーションについて2018
- Author(s)
  秋田天平、福田敦夫
- Organizer
  新学術領域研究「オシロロジー」第2回領域会議
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] 胎生期大脳基底核原基の神経前駆細胞内Ca2+シグナリングについて2018
- Author(s)
  秋田天平、福田敦夫
- Organizer
  第65回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] WNK3 Kinase regulates inwardly rectifying potassium channels in layer V pyramidal neurons of the mouse prefrontal cortex.2018
- Author(s)
  Sinha AS, Hosoi Y, Sohara E, Mutoh H, Akita T, Uchida S, Fukuda A
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] De novo mutants of CaMKIIα/β responsible for neurodevelopmental disorders upregulate A-type voltage-dependent K+ currents in hippocampal neurons.2018
- Author(s)
  Akita T, Aoto K, Kato M, Shiina M, Mutoh H, Nakashima M, Kuki I, Okazaki S, Magara S, Shiihara T, Yokochi K, Aiba K, Tohyama J, Ohba C, Miyatake S, Miyake N, Ogata K, Fukuda A, Matsumoto N, Saitsu H
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Biallelic variants in CNPY3, encoding an endoplasmic reticulum chaperone, cause early-onset epileptic encephalopathy.2018
- Author(s)
  Mutoh H, Kato M, Akita T, Shibata T, Wakamoto H, Ikeda H, Kitaura H, Aoto K, Nakashima M, Wang T, Ohba C, Miyatake S, Miyake N, Kakita A Miyake K, Fukuda A, Matsumoto N, Saitsu H
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] てんかん及び神経発達障害をもたらすCaMKII新生突然変異体の発見2017
- Author(s)
  秋田天平、青戸一司、加藤光広、椎名政昭、武藤弘樹、中島光子、九鬼一郎、岡崎伸、眞柄慎一、椎原隆、横地健治、相場佳織、遠山潤、大場ちひろ、宮武聡子、三宅紀子、緒方一博、福田敦夫、松本直通、才津浩智
- Organizer
  新学術領域研究「オシロロジー」第2回領域会議
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Taurine depletion reduces postsynaptic GABAA receptors in layer 2/3 pyramidal neurons of the somatosensory cortex.2017
- Author(s)
  Hosoi Y, Akita T, Watanabe M, Mutoh H, Miyajima H and Fukuda A.
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県・浜松市）
- Year and Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Exploring integrated regulation of membrane excitability through analyses of epilepsy-associated gene mutations.2017
- Author(s)
  Akita T, Saitsu H, Matsumoto N, Fukuda A
- Organizer
  International Symposium Neural Oscillation Conference 2017: Problems of consciousness and neuropsychiatric disorders as network diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08534
[Presentation] Excitatory roles of WNK3 in layer V pyramidal neurons in the prefrontal cortex.2017
- Author(s)
  Sinha Adya S, Hosoi Y, Sohara E, Mutoh H, Akita T, Uchida S and Fukuda A.
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県・浜松市）
- Year and Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Mild functional impairment of neuronal K+-Cl－ cotransporter KCC2 by biallelic mutations causes migrating focal seizures and severe developmental delay.2017
- Author(s)
  Akita T, Saitsu H, Watanabe M, Matsumoto N and Fukuda A.
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県・浜松市）
- Year and Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Partial loss of neuronal KCC2 function by biallelic SLC12A5 mutations causes migrating focal seizures and developmental delay.2016
- Author(s)
  Watanabe M, Akita T, Saitsu H, Matsumoto N and Fukuda A.
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] タウリン欠乏は生後の大脳皮質感覚野錐体細胞への抑制性シナプス入力を減少させる.2016
- Author(s)
  細井泰志, 秋田天平, 武藤弘樹, 渡部美穂, 伊藤崇志, 福田敦夫.
- Organizer
  第63回中部日本生理学会
- Place of Presentation
  生理学研究所（愛知県・岡崎市）
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] De novo Kv2.1 mutants causing infantile generalized seizures and psychomotor developmental delay inhibit repetitive neuronal firing.2016
- Author(s)
  Akita, T., Saitsu, H., Matsumoto, N. and Fukuda, A.
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Excitatory roles of WNK3 in layer V pyramidal neurons in the prefrontal cortex.2016
- Author(s)
  Sinha Adya S, Hosoi Y, Sohara E, Mutoh H, Akita T, Uchida S, Fukuda A.
- Organizer
  第63回中部日本生理学会
- Place of Presentation
  生理学研究所（愛知県・岡崎市）
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] De novo Kv2.1 mutants causing infantile generalized seizures and psychomotor developmental delay inhibit repetitive neuronal firing.2016
- Author(s)
  Akita, T., Saitsu, H., Matsumoto, N. and Fukuda, A.
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-25293052
[Presentation] 乳児焦点移動性部分発作はSLC12A5遺伝子の両アレル変異によるカリウム-クロライド共役担体(KCC2)機能の低下により引き起こされる.2016
- Author(s)
  渡部美穂, 秋田天平, 才津浩智, 松本直通, 福田敦夫.
- Organizer
  第63回中部日本生理学会
- Place of Presentation
  生理学研究所（愛知県・岡崎市）
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] De novo mutations in Kv2.1 channels found in infantile epileptic patients inhibit repetitive neuronal firing.2016
- Author(s)
  Akita T, Saitsu H, Matsumoto N and Fukuda A.
- Organizer
  The 13th Korea-Japan Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscle Sciences
- Place of Presentation
  佐賀大学（佐賀県・佐賀市）
- Year and Date
  2016-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Taurine depletion reduces postnatal inhibitory synaptic inputs into layer 2/3 pyramidal neurons in the somatosensory cortex.2016
- Author(s)
  Hosoi Y, Akita T, Mutoh H, Ito T, Miyajima H and Fukuda A.
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-21
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Excitatory roles of WNK3 in layer V pyramidal neurons in the prefrontal cortex.2016
- Author(s)
  Sinha Adya S, Hosoi Y, Sohara E, Mutoh H, Akita T, Uchida S, Fukuda A.
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Impaired neuronal KCC2 function by biallelic SLC12A5 mutations in migrating focal seizures and severe developmental delay.2016
- Author(s)
  Watanabe M, Akita T, Saitsu H, Matsumoto N and Fukuda A.
- Organizer
  The 13th Korea-Japan Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscle Sciences
- Place of Presentation
  佐賀大学（佐賀県・佐賀市）
- Year and Date
  2016-08-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] 生理学者への歩み－カエルの神経から遺伝子疾患に至るまで－2016
- Author(s)
  秋田　天平
- Organizer
  第13回日韓脳科学・心筋・平滑筋合同シンポジウム関連講演会
- Place of Presentation
  国立大学法人佐賀大学医学部
- Year and Date
  2016-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-26460293
[Presentation] Taurine concentration and distribution in brain of frontaltemporal lobar degeneration patients.2015
- Author(s)
  Matsushita, S., Masaki, N, Kondo, T., Takei, S., Akatsu, H., Akita, T., Sugiyama, E., Fukuda, A., Yao, I. and Setou, M.
- Organizer
  第40回日本医用マススペクトル学会年会
- Place of Presentation
  アクトシティ浜松（静岡県・浜松市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Taurine concentration and distribution in brain of frontaltemporal lobar degeneration patients.2015
- Author(s)
  Matsushita, S., Masaki, N, Kondo, T., Takei, S., Akatsu, H., Akita, T., Sugiyama, E., Fukuda, A., Yao, I. and Setou, M.
- Organizer
  第40回日本医用マススペクトル学会年会
- Place of Presentation
  アクトシティ浜松（静岡県・浜松市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25293052
[Presentation] Roles of volume-regulated anion channels during neuronal migration in the developing brain.2015
- Author(s)
  Akita T, Furukawa T & Fukuda A
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-03-23
- Data Source
  KAKENHI-PROJECT-26460293
[Presentation] イオンチャネルにより駆動される局所的な細胞容積調節と細胞間情報伝達の意義を明らかにする2014
- Author(s)
  秋田天平
- Organizer
  水シグナリングの分子動態から病態へ
- Place of Presentation
  福井市地域交流プラザ　アオッサ（福井県）
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] 母体由来タウリンによるトニックGABAA受容体刺激が胎仔脳の放射状細胞移動に及ぼす影響2014
- Author(s)
  福田敦夫，古川智範，山田順子，秋田天平，松島芳隆，柳川右千夫
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26460293
[Presentation] et al. Exploring the role of anion channels in cell volume regulation and intercellular communications in the developing brain2014
- Author(s)
  Akita T, et al
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Year and Date
  2014-03-17
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Maternally-derived ambient taurine plays a pivotal role in radial migration in the embryonic mouse neocortex by tonically activating GABAA receptors.2014
- Author(s)
  Fukuda, A., Furukawa, T., Yamada, J., Akita, T., Matsushima, Y., Yanagawa, Y.
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26670512
[Presentation] Exploring the role of anion channels in cell volume regulation and intercellular communications in the developing brain.2014
- Author(s)
  Akita T, Fukuda A
- Organizer
  The 91th Annual Meeting of The Physiological Society of Japan
- Place of Presentation
  Kagoshima University, Korimoto Campus, Kagoshima, Japan
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Maternally-derived ambient taurine plays a pivotal role in radial migration in the embryonic mouse neocortex by tonically activating GABAA receptors.2014
- Author(s)
  Fukuda, A., Furukawa, T., Yamada, J., Akita, T., Matsushima, Y., Yanagawa, Y.
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-25293052
[Presentation] Activity dependent release of taurine facilitates the excitatory neurotransmission in the marginal zone of developing cerebral cortex.2013
- Author(s)
  熊田竜郎, 千太哲, 中村直人, 古川智範, 山田順子, 秋田天平, Welner Kilb, Heiko, J. Luhmann, 中原大一郎, 福田敦夫.
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293052
[Presentation] Exploring the role of local control of cell volume regulation mediated by volume-sensitive outwardly channels2013
- Author(s)
  Akita T.
- Organizer
  rectifying The (VSOR) anion 13th Hamamatsu-Kyungpook Joint Medical Symposium
- Place of Presentation
  慶北大学医学部(大邸市、韓国)
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Analysis of basic electrophysiological properties of a new isoform of ClC-3, ClC-3d.2013
- Author(s)
  Okada T, Akita T, Okada Y
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Volume-sensitive outwardly rectifying anion channels in the developing brain2013
- Author(s)
  Akita T.
- Organizer
  Cell Volume Regulation : Novel Therapeutic Targets and Pharmacological Approaches
- Place of Presentation
  M.V. Lomonosov Moscow State University (Russia)
- Year and Date
  2013-08-28
- Invited
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Volume-sensitive outwardly rectifying (VSOR) anion channels in the developing brain2013
- Author(s)
  Akita T, et al
- Organizer
  The 11th Korea-Japan Joint Symposi m of Brain Sciences, and Cardiac and Smooth Muscle Sciences
- Place of Presentation
  アクトシティ浜松コングレスセンター
- Year and Date
  2013-09-06
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Volume-sensitive outwardly rectifying anion channels in the developing brain.2013
- Author(s)
  Akita T
- Organizer
  Cell Volume Regulation: Novel Therapeutic Targets and Pharmacological Approaches
- Place of Presentation
  M.V. Lomonosov Moscow State University, Russia
- Invited
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Volume-sensitive outwardly rectifying (VSOR) anion channels in the developing brain.2013
- Author(s)
  Akita T, Fukuda A
- Organizer
  The 11th Korea-Japan Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscle Sciences
- Place of Presentation
  Act City Hamamatsu Congress Center, Hamamatsu, Japan
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] アストログリアにおけるATP及びグルタミン酸による細胞容積感受性外向整流性アニオンチャネル(VSOR)の容積非依存的な活性化2012
- Author(s)
  秋田天平、岡田泰伸
- Organizer
  第59回中部日本生理学会
- Place of Presentation
  自然科学研究機構　岡崎コンファレンスセンター（愛知県）
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Autocrine actions of ATP and glutamate activate volume-sensitive outwardly rectifying (VSOR) anion channels via Ca2+ nanodomains in mouse astrocytes.2012
- Author(s)
  Akita T, Fedorovich SV, Okada Y
- Organizer
  Purine 2012
- Place of Presentation
  九州大学医学部　百年講堂（福岡県）
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Ca2+ nanodomain-mediated component of swelling-induced volume-sensitive outwardly rectifying (VSOR) anion channel activity in mouse astrocytes.2012
- Author(s)
  Akita T, Fedorovich S, Okada Y
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館（長野県）
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Ca^<2+> nanodomain-mediated component of swelling-induced volume-sensitive outwardly rectifying (VSOR) anion channel activity in mouse astrocytes2012
- Author(s)
  Akita T, et al
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Autocrine actions of ATP and glutamate activate volume-sensitive outwardly rectifying (VSOR) anion channels via Ca^<2+> nanodomains in mouse astrocytes2012
- Author(s)
  Akita T, et al
- Organizer
  Purine 2012
- Place of Presentation
  九州大学医学部
- Year and Date
  2012-05-31
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Ca2+ nanodomain-mediated regulation of volume-sensitive outwardly rectifying (VSOR) anion channels in mouse astrocytes.2011
- Author(s)
  Akita T
- Organizer
  Cell Volume Regulation Meeting 2011 Hydration & Cell Volume Regulation(招待講演)
- Place of Presentation
  チュービンゲン大学（ドイツ）
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] アストログリアにおける自己放出されたATPによる細胞容積感受性外向整流性アニオンチャネル(VSOR)のCa2+依存的な活性化2011
- Author(s)
  秋田天平、Sergei V Fedorovich、岡田泰伸
- Organizer
  第58回中部日本生理学会
- Place of Presentation
  福井県県民ホール（福井県）
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] アストログリアにおける自己放出されたATPによる細胞容積感受性外向整流性アニオンチャネル(VSOR)のCa^<2+>依存的な活性化2011
- Author(s)
  秋田天平他
- Organizer
  第58回中部日本生理学会
- Place of Presentation
  福井県県民ホール
- Year and Date
  2011-11-02
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Ca^<2+>-mediated augmentation of volume-sensitive outwardly rectifying (VSOR) anion channel activity triggered by autocrine action of ATP in mouse astrocytes2011
- Author(s)
  Akita T, et al
- Organizer
  The 7th Congress of the Federation of Asian and Oceanian Physiological Societies (FAOPS)
- Place of Presentation
  台大醫院國際會議中心(台湾)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Ca^<2+> nanodomain-mediated regulation of volume-sensitive outwardly rectifying (VSOR) anion channels in mouse astrocytes2011
- Author(s)
  Akita T.
- Organizer
  Cell Volume Regulation Meeting 2011: Hydration & Cell Volume Regulation
- Place of Presentation
  Eberhard Karls Universität Tübingen (Germany)
- Year and Date
  2011-09-04
- Invited
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Ca2+-mediated augmentation of volume-sensitive outwardly rectifying (VSOR) anion channel activity triggered by autocrine action of ATP in mouse astrocytes.2011
- Author(s)
  Akita T, Fedorovich S, Okada Y
- Organizer
  The 7th Congress of the Federation of Asian and Oceanian Physiological Societies (FAOPS)
- Place of Presentation
  台大醫院國際會議中心（台湾）
- Data Source
  KAKENHI-PROJECT-23612008
[Presentation] Ca^<2+> nanodomain-mediated regulation of volume-sensitive outwardly rectifying (VSOR) anion channels in mouse astrocytes. Abstract p72011
- Author(s)
  Akita T, Okada Y
- Organizer
  Hydration & Cell Volume Regulation: Cell Volume regulation Meeting 2011
- Place of Presentation
  Tubingen, Germany
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying (VSOR) anion channels via "Ca^<2+> nanodomains" in mouse cortical astrocytes.2010
- Author(s)
  秋田天平(発表代表者)
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール・マリオス(岩手県)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21790216
[Presentation] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying (VSOR) anion channels via “Ca^<2+> nanodomains” in mouse cortical astrocytes. J. Physiol. Sci. 60 (Suppl), S662010
- Author(s)
  Akita T, Okada Y
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール・いわて県民情報交流センター, 盛岡, (シンポジウム口演)
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying (VSOR) anion channels via "Ca^<2+> nanodomains" in mouse cortical astrocytes2010
- Author(s)
  秋田天平
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  いわて県民情報交流センター盛岡市民文化ホール(岩手)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Bradykinin-induced glutamate release via volume-sensitive outwardly rectifying (VSOR) anion channels in mouse cortical astrocytes. J Physiol Sci 59 Suppl 1 p3922009
- Author(s)
  Akita T, Liu H, Sabirov R, Shimizu T, Okada Y
- Organizer
  XXXVI International Congress of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying (VSOR) anion channels via "Ca^<2+> nanodomains" in mouse cortical astrocytes.2009
- Author(s)
  秋田天平(発表代表者)
- Organizer
  第40回生理学研究所国際シンポジウムPAT-CVR2009
- Place of Presentation
  岡崎コンファレンスセンター(愛知県)
- Data Source
  KAKENHI-PROJECT-21790216
[Presentation] 「Ca^<2+>ナノドメイン」を介するブラジキニン誘起性アストログリア細胞容積センサー外向整流性アニオンチャネル(VSOR)活性化機構2009
- Author(s)
  秋田天平、岡田泰伸
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県・石川県立音楽堂
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21790216
[Presentation] 「Ca^<2+>ナノドメイン」を介するブラジキニン誘起性アストログリア細胞容積センサー外向整流性アニオンチャネル(VSOR)活性化機構2009
- Author(s)
  秋田天平(発表代表者)
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県立音楽堂(石川県)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21790216
[Presentation] Bradykinin-induced glutamate release via volume-sensitive outwardly rectifying(VSOR)anion channels in mouse cortical astrocytes2009
- Author(s)
  秋田天平 et al.
- Organizer
  第36回国際生理学会
- Place of Presentation
  京都府・国立京都国際会館
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-21790216
[Presentation] Bradykinin-induced glutamate release via volume-sensitive outwardly rectifying(VSOR)anion channels in mouse cortical astrocytes2009
- Author(s)
  Tenpei Akita
- Organizer
  XXXVI International Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying(VSOR)anion channels via "Ca^<2+> nanodomains" in mouse cortical astrocytes2009
- Author(s)
  秋田天平、岡田泰伸
- Organizer
  第40回生理学研究所国際シンポジウムPAT-CVR2009
- Place of Presentation
  愛知県・岡崎コンファレンスセンター
- Data Source
  KAKENHI-PROJECT-21790216
[Presentation] Bradykinin-induced glutamate release via volume-sensitive outwardly rectifying (VSOR) anion channels in mouse cortical astrocytes.2009
- Author(s)
  秋田天平(発表代表者)
- Organizer
  第36回国際生理学会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-21790216
[Presentation] Exploring the role of local control of cell volume regulation mediated by volume-sensitive outwardly rectifying (VSOR) anion channels.
- Author(s)
  Akita T
- Organizer
  The 13th Hamamatsu-Kyungpook Joint Medical Symposium
- Place of Presentation
  School of Medicine, Kyungpook National University, Daegu, Korea
- Data Source
  KAKENHI-PROJECT-23612008

1. FUKUDA Atsuo (50254272)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
2. OKADA Yasunobu (10025661)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
3. NUMATA Tomohiro (20455223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. AKATSUKA Yuhko (90321611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OKADA Toshiaki (00373283)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. WATANABE MIHO (10399321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. HATA KENICHIRO (60360335)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAKAHASHI Nobuyuki (50370135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. INOUE Hana (20390700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. LEE Elbert (30425425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIMIZU Takahiro (40353437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. ONO Koh (00359275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOIZUMI Amane (10296551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KUKITA Fumio (40113427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. URAMOTO Hiromi (50390696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SATO Kaori (60614196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. MURAKAMI GEN (70613727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MUTOH Hiroki (60443040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
19. UCHIDA Shinichi (50262184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. 青戸一司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. ISLAM Md.rafiqul

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. ISLAM Md. Rafiqul

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 熊田竜郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 水口剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 加藤光広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 宮冬樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 宮武聡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akita Tenpei 秋田 天平

AKITA Tenpei 秋田 天平

Research Projects

Research Products

Co-Researchers

Elucidating regulatory mechanisms for neural precursor development by voltage-dependent ion channelsPrincipal Investigator

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Exploration of the integrated physiological mechanism of membrane excitability regulation through analyses of disease-causing gene mutationsPrincipal Investigator

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Exploring the mechanisms for neuronal migration and intercellular communication steered by ion channels in the embryonic brainPrincipal Investigator

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Models for developmental disorder induced by interaction of maternal stress and fetal factors

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Multimodal GABA systems responding to environmental stress

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Mechanisms and roles of volume-sensitive anion channel activation mediated by chemical transmitters released in response to cell membrane stretchPrincipal Investigator

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Molecular characterization of volume-activated anion channels and elucidation of cell death-survival switching mechanisms

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Research on the activation mechanism of volume-sensitive ion channels in neurons and gliaPrincipal Investigator

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Volume-sensor anion channel and mechano-sensor cation channel: Their functional modal shifts and molecular interaction

Principal Investigator

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Review Section

Research Institution

[Book] "Regulation of neuronal cell migration and cortical development by chloride transporter activities." In Neuronal Chloride Transporters in Health and Disease2020

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[Book] 脳科学辞典 「塩素チャネル」2013

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[Book] Patch-clamp techniques : general remarks. In Patch Clamp Techniques : From Beginning to Advanced Protocols, ed. Okada Y, pp 21-41, Springer Protocols Handbooks2012

Author(s)

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[Book] "Patch-clamp techniques: general remarks." In Patch Clamp Techniques: From Beginning to Advanced Protocols2012

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[Book] 最新パッチクランプ実験技術法（岡田泰伸編）「２章 パッチクランプ法総論」2011

Author(s)

Publisher

Akita Tenpei 秋田天平

AKITA Tenpei 秋田天平

[Book] 脳科学辞典　「塩素チャネル」2013

[Book] 最新パッチクランプ実験技術法（岡田泰伸編）「２章　パッチクランプ法総論」2011