Arai Atsushi 荒井敦

… Alternative Names

ARAI Atsushi 荒井敦

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Researcher Number	00532772
Affiliation (based on the past Project Information) *help	2018 – 2023: 松本歯科大学, 歯学部, 准教授 2018: 松本歯科大学, 歯学部, 講師 2016 – 2017: 松本歯科大学, 歯学部, 助教 2009 – 2012: Matsumoto Dental University, 歯学部, 助教
Review Section/Research Field	Principal Investigator Orthodontic/Pediatric dentistry / Orthodontics/Pediatric dentistry Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Functional basic dentistry / Dental engineering/Regenerative dentistry
Keywords	Principal Investigator 破骨細胞 / RANKL / 破骨細胞前駆細胞 / 歯の移動 / 矯正力 / M-CSF / c-Fos / RANK / TRAF6 / LC3B … More / Beclin 1 / オートファジー / Beclin1 / Autophagy / c-fms / c-fmsマクロファージ / QOP / H-CSF / メカニカルストレス / マクロファージ … More Except Principal Investigator 骨芽細胞 / Wnt / プロテオゲノミクス / 骨髄間葉系幹細胞 / 骨髄造血 / レプチン受容体陽性細胞 / osteoprotegerin / 老化 / 間葉系細胞 / 骨 / レプチン受容体 / OPG / 骨格幹細胞 / 骨髄 / 副甲状腺ホルモン / 脂肪細胞 / 破骨細胞 / 高感度レポーターシステム / Wnt活性レポーター / Crispr-A / リン酸化質量分析 / 骨形成 / 歯髄細胞 / 骨細胞 / プロテオミクス / VDR / 骨ミネラル代謝 / Ryk / PTH / 修復象牙質 / 細胞枯渇実験 / フェイトマッピング解析 / 細胞の枯渇実験 / ジフテリア毒素 / 歯髄幹細胞 / 第三象牙質 / 象牙芽細胞 / 光触媒 / 生体材料 / 焼結体 / 光触媒作用 / ルチル型二酸化チタン / 酸化チタン / バイオセラミックス / 傾斜機能 / 二酸化チタン Less

Development of bone anabolic drugs via evaluation of Wnt activity
- Principal Investigator
  
  Nakamichi Yuko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Matsumoto Dental University
Exploration of druggable targets for metabolic bone diseases using sensitive reporter systems and integrative proteogenomic approaches
- Principal Investigator
  
  中道裕子
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Matsumoto Dental University
Analysis fo osteoclast-regulated bone marrow aging and its application to rejuvenation of hematopoietic function
- Principal Investigator
  
  Toshihide Mizoguchi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tokyo Dental College
Development of bioceramics with biocompatibility and antibacterial properties
- Principal Investigator
  
  Yokoi Yukiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Matsumoto Dental University
Analysis of reparative dentin formation regulated by dental pulp stem cells using a fate mapping approach
- Principal Investigator
  
  Mizoguchi Toshihide
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College
  Matsumoto Dental University
Dose orthodontic force induce autophagy of osteoclast precursor ?Principal Investigator
- Principal Investigator
  
  Arai Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Roles of an atypical Wnt receptor, Ryk, for bone formation and mineral metabolism
- Principal Investigator
  
  Nakamichi Yuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Analysis of osteoclastogenesis regulated by orthodontic forcePrincipal Investigator
- Principal Investigator
  
  ARAI Atsushi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Analysis of osteoclast niche regulated by correction power loadPrincipal Investigator
- Principal Investigator
  
  ARAI Atsushi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University

All 2021 2020 2019 2018 2017 2016 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Odontoblast death drives cell-rich zone-derived dental tissue regeneration2021
- Author(s)
  Zhao Lijuan、Ito Shinichirou、Arai Atsushi、Udagawa Nobuyuki、Horibe Kanji、Hara Miroku、Nishida Daisuke、Hosoya Akihiro、Masuko Rinya、Okabe Koji、Shin Masashi、Li Xianqi、Matsuo Koichi、Abe Shinichi、Matsunaga Satoru、Kobayashi Yasuhiro、Kagami Hideaki、Mizoguchi Toshihide
- Journal Title
  
  Bone
  
  Volume: 150 Pages: 116010-116010
- DOI
  10.1016/j.bone.2021.116010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10065, KAKENHI-PROJECT-19K10171, KAKENHI-PROJECT-19K22727, KAKENHI-PROJECT-20K18466, KAKENHI-PROJECT-20H03853, KAKENHI-PROJECT-19H03833, KAKENHI-PROJECT-21K09961, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-21K19615
[Journal Article] RANKL/OPG ratio regulates odontoclastogenesis in damaged dental pulp2021
- Author(s)
  Daisuke Nishida , Atsushi Arai , Lijuan Zhao , Mengyu Yang , Yuko Nakamichi , Kanji Horibe , Akihiro Hosoya , Yasuhiro Kobayashi , Nobuyuki Udagawa , Toshihide Mizoguchi
- Journal Title
  
  Scientific reports
  
  Volume: 11(1) Issue: 1 Pages: 4575-4575
- DOI
  10.1038/s41598-021-84354-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K24156, KAKENHI-PROJECT-19K10171, KAKENHI-PROJECT-19K22727, KAKENHI-PROJECT-20H03853, KAKENHI-PROJECT-20H03872, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-19K22728, KAKENHI-PROJECT-20K21689, KAKENHI-PROJECT-21K19615, KAKENHI-PROJECT-19KK0234, KAKENHI-PROJECT-23K21488
[Journal Article] Beclin1 modulates bone homeostasis by regulating osteoclast and chondrocyte differentiation2019
- Author(s)
  Atsushi Arai, Sol Kim, Vadim Goldshteyn, Terresa Kim, No-Hee Park, Cun-Yu Wang, Reuben Kim
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11798
[Journal Article] Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor-Marked Stromal Population from Adipogenic to Osteoblastic Lineage.2019
- Author(s)
  Yang M, Arai A, Udagawa N, Zhao L, Nishida D, Murakami K, Hiraga T, Takao-Kawabata R, Matsuo K, Komori T, Kobayashi Y, Takahashi N, Isogai Y, Ishizuya T, Yamaguchi A, Mizoguchi T
- Journal Title
  
  J Bone Miner Res
  
  Volume: 34 Issue: 10 Pages: 1952-1963
- DOI
  10.1002/jbmr.3811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-18K19656, KAKENHI-PROJECT-19K18955, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-19H03833, KAKENHI-PROJECT-16KK0190, KAKENHI-PROJECT-19K22727
[Journal Article] Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy2017
- Author(s)
  Yang Mengyu、Arai Atsushi、Udagawa Nobuyuki、Hiraga Toru、Lijuan Zhao、Ito Susumu、Komori Toshihisa、Moriishi Takeshi、Matsuo Koichi、Shimoda Kouji、Zahalka Ali H.、Kobayashi Yasuhiro、Takahashi Naoyuki、Mizoguchi Toshihide
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 4928-4928
- DOI
  10.1038/s41598-017-05401-1
- NAID
  120006576162
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11798, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11048, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-16K15781, KAKENHI-PROJECT-26221310
[Journal Article] IL-36 Induces Bisphosphonate-Related Osteonecrosis of the Jaw-Like Lesions in Mice by Inhibiting TGF-β-Mediated Collagen Expression2017
- Author(s)
  Kim Sol、Williams Drake W、Lee Cindy、Kim Terresa、Arai Atsushi、Shi Songtao、Li Xinmin、Shin Ki-Hyuk、Kang Mo K、Park No-Hee、Kim Reuben H
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 32 Issue: 2 Pages: 309-318
- DOI
  10.1002/jbmr.2985
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11798
[Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012
- Author(s)
  Arai A, et al
- Journal Title
  
  J Cell Sci
  
  Volume: (印刷中) Pages: 2910-2917
- DOI
  10.1242/jcs.099986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
[Journal Article] Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice.2012
- Author(s)
  Nakamichi Y et al.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109 Issue: 25 Pages: 10006-10011
- DOI
  10.1073/pnas.1207361109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
[Journal Article] Lineage-Committed Osteoclast Precursors Circulate in Blood and Settle Down Into Bone2011
- Author(s)
  Muto, A, Mizoguchi, T, Udagawa, N., Ito, S, Kawahara, I, Abiko, Y, Arai, A., Harada, S., Kobayashi, Y., Nakamichi, Y, Penninger, JM, Noguchi, T, Takahashi, N.
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 26 Issue: 12 Pages: 2978-2990
- DOI
  10.1002/jbmr.490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-21390498, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390550, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-21592615, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-23792492
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010
- Author(s)
  Takahashi N, Muto A, Arai A, Mizoguchi T.
- Journal Title
  
  Adv Exp Med Biol. 658
  
  Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792104
[Journal Article] 海外文献紹介「インターフェロン調節因子8は破骨細胞形成を抑制することにより骨代謝を制御する」2009
- Author(s)
  荒井敦
- Journal Title
  
  骨粗鬆症治療 Vol.8 No.4
  
  Pages: 89-89
- Data Source
  KAKENHI-PROJECT-21792104
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009
- Author(s)
  Mizoguchi T Mizoguchi T, Muto A, Udagawa N, Arai A, Yamashita T, Hosoya A, Ninomiya T, Nakamura H, Yamamoto Y, Kinugawa S, Nakamura M, Nakamichi Y, Kobayashi Y, Nagasawa S, Oda K, Tanaka H, Tagaya M, Penninger JM, Ito M, Takahashi N
- Journal Title
  
  Journal of Cell Biology 184
  
  Pages: 541-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792104
[Journal Article] インターフェロン調節因子8は破骨細胞形成を抑制することにより骨代謝を制御する2009
- Author(s)
  荒井敦
- Journal Title
  
  骨粗鬆症治療 8
  
  Pages: 89-89
- Data Source
  KAKENHI-PROJECT-21792104
[Presentation] RANKL/OPG比は損傷した歯髄における破歯細胞形成を調節する2021
- Author(s)
  西田大輔，荒井敦，堀部寛治，中道裕子，細矢明宏，中村浩彰，小林泰浩，宇田川信之，溝口利英
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0234
[Presentation] RANKL/OPG比は損傷した歯髄における破歯細胞形成を調節する2021
- Author(s)
  西田大輔、荒井敦、堀部寛治、中道裕子、細谷明宏、中村浩彰、小林泰浩、宇田川信之、溝口利英
- Organizer
  第63回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] RANKL/OPG比は損傷した歯髄における破歯細胞形成を調節する2021
- Author(s)
  西田大輔，荒井敦，堀部寛治，中道裕子，細矢明宏，中村浩彰，小林泰浩，宇田川信之，溝口利英
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22728
[Presentation] RANKL/OPG比は損傷した歯髄における破歯細胞形成を調節する2021
- Author(s)
  西田大輔、荒井敦、堀部寛治、中道裕子、細谷明宏、中村浩彰、小林泰浩、宇田川信之、溝口利英
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] 象牙芽細胞の枯渇は象牙芽細胞の分化と石灰化を誘導する2020
- Author(s)
  溝口利英, 趙麗娟, 荒井敦 ,堀部寛治, 細矢明宏, 岡部幸司, 進正史, 小林泰浩, 宇田川信之, 高橋直之
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] 破歯/破骨細胞形成を負に制御する歯髄環境の解析2020
- Author(s)
  西田大輔, 荒井敦, 宇田川信之, 中村美どり, 堀部寛治, 小林泰浩, 高橋直之, 溝口利英
- Organizer
  第5回日本骨免疫学会ウインタースクール
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] チャネルキナーゼTRPM7 の骨格形成における発現と軟骨形成制御2019
- Author(s)
  進正史，森志穂美，溝口利英，岡本富士雄，鍛治屋浩，荒井敦，宇田川信之，岡部幸司
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 象牙芽細胞の枯渇は象牙質形成を誘導する2019
- Author(s)
  趙麗娟，荒井敦，宇田川信之，細矢明宏，岡部幸司，進正史，李憲起，小林泰浩，高橋直之，溝口利英
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 象牙芽細胞の枯渇は象牙質形成を誘導する2019
- Author(s)
  趙麗娟，荒井敦，宇田川信之，細矢明宏，岡部幸司，進正史，李憲起，小林泰浩，高橋直之，溝口利英
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] チャネルキナーゼTRPM7 の骨格形成における発現と軟骨形成制御2019
- Author(s)
  進正史，森志穂美，溝口利英，岡本富士雄，鍛治屋浩，荒井敦，宇田川信之，岡部幸司
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] 破歯/破骨細胞形成を負に制御する歯髄環境の解析2019
- Author(s)
  西田大輔, 荒井敦, 宇田川信之, 中村美どり, 堀部寛治, 小林泰浩, 高橋直之, 溝口利英
- Organizer
  第5回日本骨免疫学会ウインタースクール
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] 破歯/破骨細胞形成を負に制御する歯髄環境の解析2019
- Author(s)
  西田大輔，荒井敦，宇田川信之，中村美どり，堀部寛治，小林泰浩，高橋直之，溝口利英
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 歯髄における破歯細胞抑制メカニズムの解析2019
- Author(s)
  西田大輔, 荒井敦, 宇田川信之, 中村美どり, 堀部寛治, 小林泰浩, 高橋直之, 溝口利英
- Organizer
  第4回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 歯髄における破歯細胞抑制メカニズムの解析2019
- Author(s)
  西田大輔, 荒井敦, 宇田川信之, 中村美どり, 堀部寛治, 小林泰浩, 高橋直之, 溝口利英
- Organizer
  第4回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] 破歯/破骨細胞形成を負に制御する歯髄環境の解析2019
- Author(s)
  西田大輔, 荒井敦, 宇田川信之, 中村美どり, 堀部寛治, 小林泰浩, 高橋直之, 溝口利英
- Organizer
  第5回日本骨免疫学会ウインタースクール
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 象牙芽細胞の枯渇は修復象牙質を誘導する2019
- Author(s)
  趙麗娟, 荒井敦, 堀部寛治, 細矢明宏, 増子倫也, 小林泰浩, 宇田川信之, 高橋直之, 李憲起, 各務秀明, 溝口利英
- Organizer
  第4回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] 象牙芽細胞の枯渇は修復象牙質を誘導する2019
- Author(s)
  趙麗娟, 荒井敦, 堀部寛治, 細矢明宏, 増子倫也, 小林泰浩, 宇田川信之, 高橋直之, 李憲起, 各務秀明, 溝口利英
- Organizer
  第4回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 破歯/破骨細胞形成を負に制御する歯髄環境の解析2019
- Author(s)
  西田大輔，荒井敦，宇田川信之，中村美どり，堀部寛治，小林泰浩，高橋直之，溝口利英
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] Depletion of odontoblasts induces reparative dentin formation2019
- Author(s)
  Zhao L., Arai A., Udagawa N., Horibe K., Hosoya A., Masuko R., Okabe K., Shin M., Kobayashi Y., Takahashi N., Li X., Kagami H., Mizoguchi T.
- Organizer
  The 7th Seoul Symposium on Bone Health in conjunction with the 31th Spring Scientific Congress of Korean Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] Depletion of odontoblasts induces reparative dentin formation2019
- Author(s)
  Zhao L., Arai A., Udagawa N., Horibe K., Hosoya A., Masuko R., Okabe K., Shin M., Kobayashi Y., Takahashi N., Li X., Kagami H., Mizoguchi T.
- Organizer
  The 7th Seoul Symposium on Bone Health in conjunction with the 31th Spring Scientific Congress of Korean Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22727
[Presentation] Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) plays important roles in the induction of both bone-resorbing activity of osteoclasts and osteoblast differentiation.2018
- Author(s)
  Udagawa N., Koide M., Uehara S., Arai A., Mizoguchi T., Yamashita T., Nakamura M., Kobayashi Y., Takahashi N., Kumakura S., Fukuda C., Tsuda E.
- Organizer
  Annual Meeting of the American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 骨髄間葉系幹細胞は低レベルにRunx2を発現している2018
- Author(s)
  溝口利英, 楊孟雨, 荒井敦, 小林泰浩, 宇田川信之, 高橋直之
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 歯髄における破歯細胞抑制メカニズムの解析2018
- Author(s)
  西田大輔, 荒井敦, 宇田川信之, 中村美どり, 堀部寛治, 小林泰浩, 高橋直之, 溝口利英
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 骨髄間葉系幹細胞は低レベルにRunx2を発現している2018
- Author(s)
  溝口利英、楊孟雨、荒井敦、小林泰浩、宇田川信之、高橋直之
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] 象牙芽細胞の枯渇は修復象牙質を誘導する2018
- Author(s)
  趙麗娟, 荒井敦, 堀部寛治, 楊孟雨, 細矢明宏, 小林泰浩, 宇田川信之, 高橋直之, 溝口利英
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 破骨細胞に発現するSiglec-15の中和抗体は骨吸収を抑制しながら骨芽細胞の分化を促進する2018
- Author(s)
  宇田川信之, 小出雅則, 上原俊介, 荒井敦, 溝口利英, 山下照仁, 中村美どり, 小林泰浩, 高橋直之, 熊倉誠一郎, 福田千恵, 津田英資
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 修復象牙質形成に対する象牙芽細胞死の重要性2018
- Author(s)
  趙麗娟, 荒井敦, 宇田川信之, 堀部寛治, 小林泰浩, 高橋直之, 李憲起, 各務秀明, 溝口利英
- Organizer
  第4回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] Analysis of PTH-induced osteoblastic differentiation from BM-MSCs2018
- Author(s)
  楊孟雨，荒井敦，宇田川信之，平賀徹，小林泰浩，高橋直之，溝口利英
- Organizer
  第4回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 象牙芽細胞の枯渇は修復象牙質を誘導する2018
- Author(s)
  趙麗娟, 荒井敦, 堀部寛治, 細矢明宏, 小林泰浩, 宇田川信之, 高橋直之, 李憲起, 各務秀明, 溝口利英
- Organizer
  第87回松本歯科大学学会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 破骨細胞に発現するSiglec-15の骨代謝カップリングにおける重要性2018
- Author(s)
  宇田川信之, 上原俊介, 小出雅則, 荒井敦, 溝口利英, 中村美どり,小林泰浩, 高橋直之, 福田千恵, 津田英資
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 修復象牙質形成における象牙芽細胞死の重要性2018
- Author(s)
  趙麗娟, 溝口利英, 荒井敦, 堀部寛治, 宇田川信之, 高橋直之, 李憲起, 各務秀明
- Organizer
  第72回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 間葉系幹細胞由来TRPM7による骨格形成制御2018
- Author(s)
  進正史, 溝口利英, 岡本富士雄, 鍛冶屋浩, 荒井敦, 宇田川信之, 岡部幸司
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 破骨細胞に発現するSiglec-15の骨代謝カップリングにおける重要性2018
- Author(s)
  宇田川信之、上原俊介、小出雅則、荒井敦、溝口利英、中村美どり、小林泰浩、高橋直之、福田千恵、津田英資
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] Autophagy関連遺伝子Beclin 1は破骨細胞分化を誘導する2018
- Author(s)
  荒井敦、宇田川信之、高橋直之、Wang Cun-yu, Kim Reuben
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] 破骨細胞に発現するSiglec-15の骨代謝カップリングにおける重要性2017
- Author(s)
  20.宇田川信之, 上原俊介, 小出雅則, 荒井敦, 溝口利英, 中村美どり,小林泰浩, 高橋直之, 福田千恵, 津田英資
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] オートファジーの活性は破骨細胞分化を誘導する2017
- Author(s)
  荒井敦，山田一尋，宇田川信之，高橋直之，ワンクンユー，キムリューベン
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] Autophagyの活性は破骨細胞分化を誘導する2017
- Author(s)
  荒井敦, 山田一尋, 宇田川信之, 高橋直之, Wang, Cun-Yu, Kim, Reuben
- Organizer
  第２回日本骨免疫学会ウインターセミナー
- Place of Presentation
  ホテルマロウド軽井沢 (長野)
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] isphosphonate inhibits bone resorption by blocking autophagy in osteoclasts.2017
- Author(s)
  Kim S, Goldshteyn A, Arai A, Park NH, Kim RH
- Organizer
  American Society for Bone and Mineral Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] 髄間葉系幹細胞は低レベルにRunx2を発現している2017
- Author(s)
  溝口利英, 楊孟雨, 荒井敦, 小林泰浩, 宇田川信之, 高橋直之
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] 矯正力負荷によるAutophagyの活性は破骨細胞分化を誘導する2016
- Author(s)
  荒井敦, 宇田川信之, Kim, Reuben，山田一尋
- Organizer
  第75回日本矯正歯科学会大会
- Place of Presentation
  アスティ徳島 (徳島)
- Year and Date
  2016-11-07
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] RANKL Induces Ubiquitination of Autophagy Protein Beclin1, and Mediates Osteoclast Differentiation2016
- Author(s)
  A.Arai, S.Kim, T.Kim, C.Lee, C.-Y.Wang, N.-H.Park, R.Kim
- Organizer
  94th General session of International Association of Dental Research
- Place of Presentation
  COEX Convention Center (Seoul, Korea)
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] c-Fos plays an essential role in up-regulation of RANK expression in osteoclast precursors2012
- Author(s)
  Atsushi Arai
- Organizer
  2012 the American Society for Bone and Mineral Research Annual Meeting
- Place of Presentation
  Minneapolis USA
- Data Source
  KAKENHI-PROJECT-23792455
[Presentation] in vivoにおける破骨細胞分化機構の解析-M-CSFはc-Fosを介し前駆細胞のRANKを上昇する2011
- Author(s)
  荒井敦, 溝口利英, 小林泰浩, 山下照仁, 山田一尋, 宇田川信之, 高橋直之
- Organizer
  松本歯科大学学会
- Data Source
  KAKENHI-PROJECT-23792455
[Presentation] IOF Regionals 2nd Asia-Pacific Osteoporosis and Bone Meeting ANZBMS Annual Scientific Meeting, with JSBMR2011年 9月BMP-induced ectopic bone formation in c-Fos-deficient mice2011
- Author(s)
  M. Nakamura, T. Ninomiya, T. Mizoguchi, A. Arai, N. Takahashi, N. Udagawa
- Organizer
  第2回アジア太平洋骨粗鬆症学会プログラム抄録集
- Data Source
  KAKENHI-PROJECT-23792455
[Presentation] 生体内における破骨細胞分化機構の解析-M-CSFはc-Fosを介して破骨細胞前駆細胞のRANK発現を上昇する2011
- Author(s)
  荒井敦, 溝口利英, 原田卓, 武藤昭紀, 小林泰浩, 山下照仁, 保田尚孝, 山田一尋,宇田川信之,高橋直之
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Data Source
  KAKENHI-PROJECT-23792455
[Presentation] IOF Regionals 2nd Asia-Pacific Osteoporosis and Bone Meeting ANZBMS Annual Scientific Meeting, with JSBMR2011 年 9 月 c-Fos plays an essential role in up-regulation of RANK expression in osteoclast precursors2011
- Author(s)
  A. Arai, T. Mizoguchi , Y. Kobayashi ,T.Yamashita, K. Yamada , J. M. Penninger , N. Udagawa, N. Takahashi
- Organizer
  第2回アジア太平洋骨粗鬆症学会プログラム抄録集
- Data Source
  KAKENHI-PROJECT-23792455
[Presentation] c-Fos plays an essential role in up-regulation of RANK expression in osteoclast precursors2011
- Author(s)
  Atsushi Arai, Toshihide Mizoguchi, Yasuhiro Kobayashi,Teruhito Yamashita, Kazuhiro Yamada, Josef M. PenningerNobuyuki Udagawa , and Naoyuki Takahashi
- Organizer
  IOF Regionals Asia-Pacific Osteoporosis and Bone Meeting
- Place of Presentation
  Australia(Gold Coast)
- Data Source
  KAKENHI-PROJECT-23792455
[Presentation] 生体内における破骨細胞分化機構の解析-M-CSF は c-Fos を介して破骨細胞前駆細胞の RANK 発現を上昇する-2011
- Author(s)
  荒井敦 , 溝口利英, 原田卓, 武藤昭紀, 小林泰浩, 山下照仁, 保田尚孝, 山田一尋,宇田川信之, 高橋直之
- Organizer
  第29回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-23792455
[Presentation] 細胞周期の停止した静止期破骨細胞前駆細胞(QOP)の性状解析-QOPはB細胞マーカーを発現している2009
- Author(s)
  武藤昭紀, 溝口利英, 荒井敦, 小林泰浩, 中道裕子, 吉成伸夫, 宇田川信之, 高橋直之
- Organizer
  日本骨代謝学会学術集会(第27回)
- Place of Presentation
  大阪・国際会議所
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21792104
[Presentation] c-Fos遺伝子欠損マウスを用いた静止期破骨細胞前駆細胞(QOP)の解析-c-FosはRANKの発現を誘導しQOP分化を制御する2009
- Author(s)
  荒井敦, 溝口利英, 武藤昭紀, 小林泰浩, 川原一郎, 中村美どり, 宇田川信之, 山田一尋, 高橋直之
- Organizer
  日本骨代謝学会学術集会(第27回)
- Place of Presentation
  大阪・国際会議所
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21792104
[Presentation] Characterization of cell cycle-arrested quiescent osteoclast precursors2009
- Author(s)
  溝口利英, 武藤昭紀, 宇田川信之, 荒井敦, 小林泰浩, Penninger JM, 高橋直之
- Organizer
  第26回内藤カンファレンスオステオバイオロジー
- Place of Presentation
  兵庫・淡路夢舞台国際会議場
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21792104
[Presentation] 破骨細胞前駆細胞の同定と動態解析2009
- Author(s)
  溝口利英, 武藤昭紀, 荒井敦, 小林泰浩, 中道裕子, 宇田川信之, 高橋直之
- Organizer
  運動器科学研究会(第10回)
- Place of Presentation
  東京・東京ステーションコンファレンス
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21792104

1. 宇田川信之 (70245801)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
2. Mizoguchi Toshihide (90329475)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
3. Kobayashi Yasuhiro (20264252)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
4. Nakamichi Yuko (20350829)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. Horibe Kanji (70733509)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. 岩本莉奈 (20907216)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Yokoi Yukiko (60469012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山田一尋 (40182521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 大須賀直人 (80247535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 細矢明宏 (70350824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 東俊文 (00222612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Takahashi Naoyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. Mori Tomoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Reuben Kim

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. Wang Cun-Yu

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. Major Michael Ben

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SHIN Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 安孫子宜光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 岡部幸司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 西田大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Arai Atsushi 荒井 敦

ARAI Atsushi 荒井 敦

Research Projects

Research Products

Co-Researchers

Development of bone anabolic drugs via evaluation of Wnt activity

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Exploration of druggable targets for metabolic bone diseases using sensitive reporter systems and integrative proteogenomic approaches

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Analysis fo osteoclast-regulated bone marrow aging and its application to rejuvenation of hematopoietic function

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Review Section

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Development of bioceramics with biocompatibility and antibacterial properties

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Analysis of reparative dentin formation regulated by dental pulp stem cells using a fate mapping approach

Principal Investigator

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Dose orthodontic force induce autophagy of osteoclast precursor ?Principal Investigator

Principal Investigator

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Roles of an atypical Wnt receptor, Ryk, for bone formation and mineral metabolism

Principal Investigator

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Analysis of osteoclastogenesis regulated by orthodontic forcePrincipal Investigator

Principal Investigator

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Analysis of osteoclast niche regulated by correction power loadPrincipal Investigator

Principal Investigator

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[Journal Article] Odontoblast death drives cell-rich zone-derived dental tissue regeneration2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RANKL/OPG ratio regulates odontoclastogenesis in damaged dental pulp2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Beclin1 modulates bone homeostasis by regulating osteoclast and chondrocyte differentiation2019

Author(s)

Journal Title

Data Source

[Journal Article] Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor-Marked Stromal Population from Adipogenic to Osteoblastic Lineage.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy2017

Author(s)

Arai Atsushi 荒井敦

ARAI Atsushi 荒井敦