kobayashi yasuhiro 小林泰浩

… Alternative Names

Researcher Number	20264252
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Affiliation (Current)	2020: 松本歯科大学, 総合歯科医学研究所, 教授
Affiliation (based on the past Project Information) *help	2013 – 2020: 松本歯科大学, 総合歯科医学研究所, 教授 2014: 松本歯科大学, 歯学部, 教授 2010 – 2013: 松本歯科大学, 総合歯科医学研究所, 准教授 2011: 松本歯科大学, 総合歯科医学研究所, 準教授 2007 – 2010: Matsumoto Dental University, Graduate school of oral medicine, Associate professor … More
Review Section/Research Field	Principal Investigator Orthodontic/Pediatric dentistry / 矯正・小児・社会系歯学 / Orthodontics/Pediatric dentistry / Functional basic dentistry / Medium-sized Section 57:Oral science and related fields Except Principal Investigator Functional basic dentistry / Functional basic dentistry / Morphological basic dentistry / 矯正・小児・社会系歯学 / Basic Section 57010:Oral biological science-related … More
Keywords	Principal Investigator 破骨細胞 / 骨芽細胞 / Wnt5a / Wnt / 歯の移動 / RANKL / 骨吸収 / 骨代謝回転 / 歯科矯正学 / 骨形成 … More Except Principal Investigator 破骨細胞 / 骨芽細胞 / RANKL / OPG / 骨吸収 / Wnt / 破骨細胞前駆細胞 / M-CSF / Wnt5a / Wnt非古典経路 / IL-1 / マクロファージ / 骨形成 / Rho / 骨代謝共役 / リポ多糖 / MyD88 / ビスフォスフォネート / BMP / 骨誘導因子 / 口腔生化学 / Ｗｎｔ / Ror2 / 極性化 / Osterix / Wntシグナル / 骨髄間葉系幹細胞 / PTH / QOP / ラット / オステオカルシン / カルシトニン / Rat / Osteocalcin / Glycolipid / Metalloprotease / Osteoclast / Osteoprotegerin (OPG) / Shedding / MDU1 / Pkn3 / 象牙芽細胞 / 歯髄幹細胞 / 骨細胞 / 骨髄マクロファージ / PGE_2 / ヒトCD14陽性細胞 / TAK1 / 破骨細胞形成抑制因子 / RAW264細胞 / ムラミルジペプチド / Nod2 / 骨粗鬆症治療薬 / p38MAPK / 炎症性サイトカイン / p38MAPキナーゼ / Smad / SaOS-4 / 3細胞 / カルシウム / PKC / シグナル伝達 / 破骨細胞分化阻止因子ODIF / OPG欠損マウス / 可溶性RANKL / 異所性骨化 / F4 / 80陽性マクロファージ / 石灰化硬組織 / 破骨細胞分化阻止因子(ODIF) / 異所性骨形成 / 活性型ビタミンD_3 / RANK / 大理石骨病 / サイトカイン / 癌 / 癌幹細胞 / 骨転移 / IL-34 / 破骨細胞ニッチ / 波上縁 / Wnt5a-Ror2シグナル / 低分子量Gタンパク質 / 骨芽細胞分化 / SUMO化修飾 / 分化制御 / 培養細胞 / Ｏｓｔｅｒｉｘ / ＢＭＰ / 遺伝子改変マウス / SUMO / ＲＡＮＫＬ / ＯＰＧ / Sclerostin / 非古典経路 / ニッチ / 間葉系幹細胞 / Runx2 / レプチン受容体 / ＱＯＰ / osteoprotegerin / c-Fms / 細胞周期 / 完全分子型オステオカルシン / N末端オステオカルシン / 酵素免疫測定法 / カテプシンB / カテプシンL / ピリジノリン / デオキシピリジノリン / osteocalcin / 日周期性 / Intact Osteocalcin / N-terminal Osteocalcin / Enzyme Immunnorssay / イオン化カルシウム / 低カルシウム血症 / エーテル麻酔 / 血清中イオン化Ca / 血漿中イオン化Ca / ストレス / Ionized calcium / Hypocalcemia / Ether anesthesia / 歯根吸収 / 術中モニタリング / 動揺度 / 歯肉溝浸出液 / 抗菌根抗体 / 抗歯根抗体 / root resorption / monitoring / mobility / cephalometry / orthodontics / 開咬 / 嚥下 / 異常嚥下 / 舌運動 / 異常舌運動 / openbite / swallowing / abnormal swallowing / tongue movement / D-PDMP / Processing enzyme / ODF(RANKL) / ODF / プロセッシング酵素 / プロセッシング / メタロプロテアーゼ / ADAM / _D-PDMP / Processing Enzyme / オステオプロテゲリン / アルカリフォスファターゼ / TNF / Osteoclasts / Lipopolysaccharide / Lipopeptide / Toll-like receptor / 歯胚間葉系細胞 / ES細胞 / 分化誘導能 / 上皮-間葉相互作用 / コラーゲン3D担体 / テラトーマ / feeder細胞 / キメラ胚様体 / Tooth germ mesenchymal cells / Embryonic stem cells / Induction ability / Epithelium-mesenchymal interactions / Collagen 3D carrier / Teratoma / Feeder cells / カモノハシ / オポッサム / アクチンリング / カルシトニン受容体 / カップリング因子 / クラストカイン / スクレロスチン / LIF / HtrA1 / 細胞骨格 / Autophagy / Beclin1 / 矯正力 / オートファジー / Beclin 1 / LC3B / TRAF6 / 歯の移動 / 細胞枯渇実験 / フェイトマッピング解析 / 修復象牙質 / 骨リモデリング / 脱共役因子 / Ryk / 骨ミネラル代謝 / プロテオゲノミクス / VDR / プロテオミクス / 歯髄細胞 / 第三象牙質 / PTH受容体 / Cre/loxP遺伝情報改変技術 Less

Identification of novel dental pulp stem cells and analysis of their regulatory mechanisms of differentiationOngoing
- Principal Investigator
  
  溝口利英
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Tokyo Dental College
プロテインキナーゼN3による破骨細胞機能制御機構の解明とその臨床応用Ongoing
- Principal Investigator
  
  上原俊介
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Matsumoto Dental University
骨代謝―脱共役機構の統合的解明を起点にした新たな骨および歯周疾患治療薬の開発Ongoing
- Principal Investigator
  
  小出雅則
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Matsumoto Dental University
幹細胞の分化を司る組織常在型Ｍ３マクロファージとそのマスター転写因子の同定Principal InvestigatorOngoing
- Principal Investigator
  
  小林泰浩
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Matsumoto Dental University
Analysis of reparative dentin formation regulated by dental pulp stem cells using a fate mapping approachOngoing
- Principal Investigator
  
  溝口利英
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College
  Matsumoto Dental University
Wntシグナルネットワークを基盤とした歯槽骨代謝回転制御法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  小林泰浩
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Elucidation of the osteoclast-derived cytokine-Wnt signaling network responsible for coupling between bone resorption and formation.
- Principal Investigator
  
  Takahashi Naoyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Matsumoto Dental University
Elucidation of the mechanism of bone-resorption in osteoclasts regulated by Pkn3.
- Principal Investigator
  
  Uehara Shunsuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Dose orthodontic force induce autophagy of osteoclast precursor ?
- Principal Investigator
  
  Arai Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Roles of an atypical Wnt receptor, Ryk, for bone formation and mineral metabolism
- Principal Investigator
  
  Nakamichi Yuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Did calcitonine appear as a central nerve hormone?
- Principal Investigator
  
  Udagawa Nobuyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Analysis of osteoclast precursor niche regulated by BM-MSC
- Principal Investigator
  
  Mizoguchi Toshihide
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
How is the formation site of osteoclasts determined?
- Principal Investigator
  
  Takahashi Naoyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Elucidation of Wnt signaling network controlling bone metabolism
- Principal Investigator
  
  Takahashi Naoyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
骨代謝共役を担うWntシグナルの解明
- Principal Investigator
  
  高橋直之
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Development of alveolar bone turnover control method based on Wnt5aPrincipal Investigator
- Principal Investigator
  
  Kobayashi Yasuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Elucidation of molecular mechanisms for osteoclast polarization through Wnt5a-Ror2 signaling
- Principal Investigator
  
  Uehara Shunsuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Osteoclast-derived factors for inhibiting sclerostin expression is a bone coupling factor.Principal Investigator
- Principal Investigator
  
  Kobayashi Yasuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
The effect of SUMOylation on bone formation in mouse
- Principal Investigator
  
  AKIRA Yukita
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Shizuoka University
  Matsumoto Dental University
Hematopoietic cells regulate bone metabolismPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yasuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Analysis of osteoclast niche regulated by Wnt signals.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Role of Wnt-Ror2 signals in ruffled border formation in osteoclasts
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
Roles of cancer stem cells in the development and progression of cancer metastasis to bone
- Principal Investigator
  
  HIRAGA Toru
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Matsumoto Dental University
Analysis of roles of Wnt5a in alveolar bone remodeling, and their application for orthodontic tooth movement.Principal Investigator
- Principal Investigator
  
  KOBAYASHI Yasuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
破骨細胞が分泌するWntは骨形成を誘導するか?Principal Investigator
- Principal Investigator
  
  小林泰浩
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
破骨細胞が分泌する新規骨形成誘導因子の同定
- Principal Investigator
  
  宇田川信之
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
ヒト造血系細胞再構成マウスを用いた歯槽骨リモデリング機構の解析Principal Investigator
- Principal Investigator
  
  小林泰浩
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Application of Cre-loxP system for elucidation of mechanisms in bone remodeling during tooth movementPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yasuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
An attempt the tooth embryogenesis combined with embryonic stem cells and tooth mesenchymal stem cells that originated from neural crest
- Principal Investigator
  
  YAMAKI Mariko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Matsumoto Dental University
破骨細胞分化阻止因子(ODIF)のクローニングと生理的役割の解析
- Principal Investigator
  
  高橋直之
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
The establishment of inducible osteocyte ablation mouse model to elucidate the mechanisms of maxillo-mandibular dysmorphia.Principal Investigator
- Principal Investigator
  
  HOSOYA Akihiro, 小林泰浩
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Matsumoto Dental University
Analysis of signal transduction of osteoclast differentiation factor (RANKL) in alveolar bone destruction
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Matsumoto Dental University
破骨細胞を調節するシグナル伝達系と骨・歯周疾患における骨破壊機序の解明
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Matsumoto Dental University
  Showa University
矯正力により牽引側に誘導される破骨細胞形成阻止因子発現機構の解析Principal Investigator
- Principal Investigator
  
  小林泰浩
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Nagasaki University
Design and application of new fluoroescent substrate against membrane-bound processing enzyme
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  NAGASAKI UNIVERSITY
牽引力による成熟破骨細胞のアポトーシス誘導機構の解析Principal Investigator
- Principal Investigator
  
  小林泰浩
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Nagasaki University
The development of monitoring system of root resorption during ortodontic treatment
- Principal Investigator
  
  KOBAYASHI Kazuhide
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Nagasaki University
Analysis of abnormal tongue movement by three dimensional tongue movement measurement device with bimorph piezopolymer thin film
- Principal Investigator
  
  MARUYAMA Yoichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Nagasaki University
歯牙移動における完全型ならびに断片化オステオカルシン投与の効果に関する研究Principal Investigator
- Principal Investigator
  
  小林泰浩
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Nagasaki University
Role of osteocalcin in the calcium metabolism disorder
- Principal Investigator
  
  KATO Yuzo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Significance of osteocalcin in bone metabolism
- Principal Investigator
  
  MATAKI Shiro
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University

[Book] 骨ﾍﾟﾃﾞｨｱ　骨疾患・骨代謝キーワード辞典日本骨代謝学会編、骨芽細胞と造血幹細胞2015
- Author(s)
  溝口利英、小林泰浩、中道裕子
- Total Pages
  327
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26462826
[Book] 骨ﾍﾟﾃﾞｨｱ　骨疾患・骨代謝キーワード辞典2015
- Author(s)
  宇田川信之、小林泰浩
- Total Pages
  327
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K15688
[Book] Identification of osteoclasts in culture2011
- Author(s)
  Udagawa N, Yamashita T, Kobayashi Y, Takahashi N, Nicole I zur Nieden
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment.2019
- Author(s)
  Ochiai Nagahiro、Nakachi Yutaka、Yokoo Tomotaka、Ichihara Takahiro、Eriksson Tore、Yonemoto Yuki、Kato Takehiko、Ogata Hitoshi、Fujimoto Natsuko、Kobayashi Yasuhiro、Udagawa Nobuyuki、Kaku Shinsuke、Ueki Tomokazu、Okazaki Yasushi、Takahashi Naoyuki、Suda Tatsuo
- Journal Title
  
  Commun Biol
  
  Volume: 2 Pages: 1-13
- DOI
  10.1038/s42003-019-0334-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08487, KAKENHI-PROJECT-16H05144
[Journal Article] Non-canonical Wnt signals regulate cytoskeletal remodeling in osteoclasts2018
- Author(s)
  Uehara S, Udagawa N, Kobayashi Y
- Journal Title
  
  Cell Mol Life Sci.
  
  Volume: 75 Pages: 3683-3692
- DOI
  10.1007/s00018-018-2881-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11818
[Journal Article] Roles of non-canonical Wnt signaling pathways in bone resorption2018
- Author(s)
  Kobayashi Yasuhiro、Uehara Shunsuke、Udagawa Nobuyuki
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 60 Pages: 31-35
- DOI
  10.1016/j.job.2018.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02691
[Journal Article] The HIV co-receptor CCR5 regulates osteoclast function2018
- Author(s)
  Lee JW, Hoshino A, Inoue K, Saitou T, Uehara S, Kobayashi Y, Ueha S, Matsushima K, Yamaguchi A, Imai Y, Iimura T.
- Journal Title
  
  Nature communications
  
  Volume: 8 Pages: 2226-2226
- DOI
  10.1038/s41467-017-02368-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-17K19546, KAKENHI-PROJECT-17K19728, KAKENHI-PROJECT-16K20412, KAKENHI-PROJECT-26293392, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-15H04961, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-15F15113, KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K18578
[Journal Article] Olfactomedin-like protein OLFML1 inhibits Hippo signaling and mineralization in osteoblasts2018
- Author(s)
  Murakami K, Kikugawa S, Kobayashi Y, Uehara S, Suzuki T, Kato H, Udagawa N, Nakamura Y
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 28 Pages: 419-425
- DOI
  10.1016/j.bbrc.2018.09.112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K16686
[Journal Article] Regulatory mechanisms of sclerostin expression during bone remodeling2018
- Author(s)
  Koide Masanori、Kobayashi Yasuhiro
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 37 Pages: 9-17
- DOI
  10.1007/s00774-018-0971-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-18H02980
[Journal Article] The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid Cells2018
- Author(s)
  Bando Jennifer K.、Gilfillan Susan、Song Christina、McDonald Keely G.、Huang Stanley C.-C.、Newberry Rodney D.、Kobayashi Yasuhiro、Allan David S.J.、Carlyle James R.、Cella Marina、Colonna Marco
- Journal Title
  
  Immunity
  
  Volume: 48
- DOI
  10.1016/j.immuni.2018.04.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02691
[Journal Article] Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling2017
- Author(s)
  Uehara S, Udagawa N, Mukai H, Ishihara A, Maeda K, Yamashita T, Murakami K, Nishita M, Nakamura T, Kato S, Minami Y, Takahashi N and Kobayashi Y
- Journal Title
  
  Sci. Signaling
  
  Volume: 10
- DOI
  10.1126/scisignal.aan0023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K07168, KAKENHI-PROJECT-17K08634, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-17K16686, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05152, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11377
[Journal Article] Relationship between localization of proteoglycans and induction of neurotrophic factors in mouse dental pulp2017
- Author(s)
  Yukita A, Hara M, Hosoya A, Nakamura H
- Journal Title
  
  J Oral Biosci
  
  Volume: 59 Pages: 31-37
- DOI
  10.1016/j.job.2016.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11664, KAKENHI-PROJECT-15K11093
[Journal Article] Treatment of OPG-deficient mice with WP9QY, a RANKL-binding peptide, recovers alveolar bone loss by suppressing osteoclastogenesis and enhancing osteoblastogenesis.2017
- Author(s)
  Ozaki Yuki、Koide Masanori、Furuya Yuriko、Ninomiya Tadashi、Yasuda Hisataka、Nakamura Midori、Kobayashi Yasuhiro、Takahashi Naoyuki、Yoshinari Nobuo、Udagawa Nobuyuki
- Journal Title
  
  PLoS One
  
  Volume: 12
- DOI
  10.1371/journal.pone.0184904
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-15K11402
[Journal Article] Osteogenic factor Runx2 marks a subset of leptin receptor-positive cells that sit atop the bone marrow stromal cell hierarchy2017
- Author(s)
  Yang Mengyu、Arai Atsushi、Udagawa Nobuyuki、Hiraga Toru、Lijuan Zhao、Ito Susumu、Komori Toshihisa、Moriishi Takeshi、Matsuo Koichi、Shimoda Kouji、Zahalka Ali H.、Kobayashi Yasuhiro、Takahashi Naoyuki、Mizoguchi Toshihide
- Journal Title
  
  Sci Rep
  
  Volume: 7 Pages: 4298-4298
- DOI
  10.1038/s41598-017-05401-1
- NAID
  120006576162
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11798, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-26221310, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11048, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-16K15781
[Journal Article] A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro2017
- Author(s)
  Murakami K, Kobayashi Y, Uehara S, Suzuki T, Koide M, Yamashita T, Nakamura M, Takahashi N, Kato H, Udagawa N and Nakamura Y
- Journal Title
  
  PLoS One
  
  Volume: 12
- DOI
  10.1371/journal.pone.0181126
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-17K16686, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-15K11401
[Journal Article] VDR in osteoblast-lineage cells primarily mediates vitamin D treatment-induced increase in bone mass by suppressing bone resorption2017
- Author(s)
  Nakamichi Y, Udagawa N, Horibe K, Mizoguchi T, Yamamoto Y, Nakamura T, Hosoya A, Kato S, Suda T, Takahashi N
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 32 Pages: 1297-1308
- DOI
  10.1002/jbmr.3096
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-16K11493, KAKENHI-PROJECT-16K11664, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-15KK0356, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11093
[Journal Article] Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals2017
- Author(s)
  Yamashita T, Udagawa N, Thirukonda GJ, Uehara S, Yamauchi H, Suzuki N, Li F, Kobayashi Y, Takahashi N.
- Journal Title
  
  Gen Comp Endocrinol
  
  Volume: 246 Pages: 270-278
- DOI
  10.1016/j.ygcen.2017.01.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-15K15688, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508
[Journal Article] Bone Formation Is Coupled to Resorption Via Suppression of Sclerostin Expression by Osteoclasts2017
- Author(s)
  Koide M, Kobayashi Y, Yamashita T, Uehara S, Nakamura M, Hiraoka BY, Ozaki Y, Iimura T, Yasuda H, Takahashi N and Udagawa N
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 32 Pages: 2074-2086
- DOI
  10.1002/jbmr.3175
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-26293392, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-15K11402
[Journal Article] Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator.2016
- Author(s)
  Akiyama N, Takizawa N, Miyauchi M, Yanai H, Tateishi R, Shinzawa M, Yoshinaga R, Kurihara M, Demizu Y, Yasuda H, Yagi S, Wu G, Matsumoto M, Sakamoto R, Yoshida N, Penninger JM, Kobayashi Y, Inoue J, Akiyama T.
- Journal Title
  
  J Exp Med
  
  Volume: 213 Pages: 1441-1458
- DOI
  10.1084/jem.20151780
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01150, KAKENHI-PUBLICLY-15H01176, KAKENHI-ORGANIZER-15H05935, KAKENHI-PUBLICLY-16H01631, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06496, KAKENHI-PLANNED-16H06575, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05342, KAKENHI-PROJECT-26460169, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-16H06276
[Journal Article] Regulation of bone metabolism by Wnt signals.2016
- Author(s)
  Kobayashi Y, Uehara S, Koide M, Takahashi N
- Journal Title
  
  J Biochem.
  
  Volume: 4 Pages: 387-392
- DOI
  10.1093/jb/mvv124
- NAID
  40020784053
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-16K11818
[Journal Article] Specification of tissue-resident macrophages during organogenesis.2016
- Author(s)
  Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome-Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez-Perdiguero E, Schultze JL, Beyer M, Bock C, Geissmann F
- Journal Title
  
  Ｓｃｉｅｎｃｅ
  
  Volume: ３５３
- DOI
  10.1126/science.aaf4238
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02691
[Journal Article] The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts.2016
- Author(s)
  Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 34
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25221310
[Journal Article] Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals.2016
- Author(s)
  Yamashita T, Udagawa N, Thirukonda GJ, Uehara S, Yamauchi H, Suzuki N, Li F, Kobayashi Y, Takahashi N
- Journal Title
  
  Gen Comp Endocrinol
  
  Volume: 246 Pages: 270-278
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05144
[Journal Article] The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts2016
- Author(s)
  Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 34 Pages: 395-405
- DOI
  10.1007/s00774-015-0683-1
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-16K11664
[Journal Article] Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways.2016
- Author(s)
  Weivoda MM, Ruan M, Hachfeld CM, Pederson L, Howe A, Davey RA, Zajac JD, Kobayashi Y, Williams BO, Westendorf JJ, Khosla S, Oursler MJ.
- Journal Title
  
  J Bone Miner Res.
  
  Volume: 31 Pages: 65-75
- DOI
  10.1002/jbmr.2599
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293423
[Journal Article] DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine producing metabolic pathway2015
- Author(s)
  Nishikawa et al.
- Journal Title
  
  Narure Med.
  
  Volume: 21 Pages: 281-287
- DOI
  10.1038/nm.3774
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22113007, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-25750357, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116719, KAKENHI-PROJECT-26670673, KAKENHI-PROJECT-26713010, KAKENHI-PROJECT-25253070
[Journal Article] The regulation of osteoclast differentiation by Wnt signals.2015
- Author(s)
  Kobayashi Y, Uehara S, Koide M, Takahashi N
- Journal Title
  
  Bone Key Rep
  
  Volume: 4 Pages: 713-713
- DOI
  10.1038/bonekey.2015.82
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-25293423
[Journal Article] Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a2015
- Author(s)
  Kobayashi Y, Thirukonda GJ, Nakamura Y, Koide M, Yamashita T, Uehara S, Kato H, Udagawa N, Takahashi N
- Journal Title
  
  Biochem Biopys Res Commun
  
  Volume: 463 Pages: 1278-1283
- DOI
  10.1016/j.bbrc.2015.06.102
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-15K15688, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-25293423
[Journal Article] Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a.2015
- Author(s)
  Kobayashi Y, Thirukonda GJ, Nakamura Y, Koide M, Yamashita T, Uehara S, Kato H, Udagawa N, Takahashi N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 463 Pages: 1278-1283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670792
[Journal Article] Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization2015
- Author(s)
  Kanemoto S, Kobayashi Y, Yamashita T, Miyamoto T, Cui M, Asada R, Cui X, Hino K, Kaneko M, Takai T, Matsuhisa K, Takahashi N, Imaizumi K.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 128 Pages: 4353-4365
- DOI
  10.1242/jcs.176057
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-15K18377, KAKENHI-PROJECT-15K21706
[Journal Article] The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts.2015
- Author(s)
  Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y
- Journal Title
  
  J Bone Miner Metab
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15688
[Journal Article] Enhanced bone-forming activity of side population cells in the periodontal ligament.2014
- Author(s)
  Ninomiya T, Hiraga T, Hosoya A, Ohnuma K, Ito Y, Takahashi M, Ito S, Asashima M, Nakamura H.
- Journal Title
  
  Cell Transplantation
  
  Volume: (in press) Pages: 691-701
- DOI
  10.3727/096368913x663587
- URL
  http://dx.doi.org/
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-24592785, KAKENHI-PROJECT-24592786
[Journal Article] Stability of mRNA influences osteoporotic bone mass via Cnot32014
- Author(s)
  Watanabe, C. Morita, M. Yamamoto T. (13名)
- Journal Title
  
  Ｐｒｏｃ　Ｎａｔｌ　Ａｃａｃ　Ｓｃｉ　ＵＳＡ
  
  Volume: Vol.111 Pages: 111-118
- DOI
  10.1073/pnas.1316932111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-23390471, KAKENHI-PROJECT-24659833, KAKENHI-PUBLICLY-25121734, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462287, KAKENHI-PROJECT-25463168, KAKENHI-PROJECT-25670639, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-26670814
[Journal Article] Arctigenin Inhibits Osteoclast Differentiation and Function by Suppressing Both Calcineurin-Dependent and Osteoblastic Cell-Dependent NFATc1 Pathways.2014
- Author(s)
  Yamashita T, Uehara S, Udagawa N, Li F, Kadota S, Esumi H, Kobayashi Y, Takahashi N
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Pages: 1-12
- DOI
  10.1371/journal.pone.0085878
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592821, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-25670793, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26670814
[Journal Article] Noncanonical Wnt5a enhances Wnt/beta-catenin signaling during osteoblastogenesis2014
- Author(s)
  Okamoto, M., Udagawa, N., Yamashita, T., Nakamichi, Y., Uehara, S., Kato, H., Saito, N., Minami, Y., Takahashi, N., Kobayashi, Y.
- Journal Title
  
  Ｓｃｉ　Ｒｅｐ
  
  Volume: 4 Pages: 137-146
- DOI
  10.1038/srep04493
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23112007, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-24240076, KAKENHI-PROJECT-24241045, KAKENHI-PROJECT-24390080, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592821, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462385, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-25670793, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26670814
[Journal Article] Localization of SUMOylation factors and Osterix in odontoblast lineage cells during dentin formation and regeneration2013
- Author(s)
  Hosoya A, Yukita A, Ninomiya T, Hiraga T, Yoshiba K, Yoshiba N, Kasahara E, Nakamura H.
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: (in press) Pages: 201-11
- DOI
  10.1007/s00418-013-1076-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-24592785, KAKENHI-PROJECT-24592786, KAKENHI-PROJECT-24592863
[Journal Article] Roles of Wnt signals in bone resorption during physiological and pathological states2013
- Author(s)
  Maeda K et al.
- Journal Title
  
  J. Mol. Med
  
  Volume: 91 Pages: 15-23
- DOI
  10.1007/s00109-012-0974-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310
[Journal Article] Osteoprotegerin-deficient male mice as a model for severe alveolar bone loss: Comparison with RANKL-overexpressing transgenic male mice2013
- Author(s)
  Koide M et al.
- Journal Title
  
  Endocrinology
  
  Volume: 190 Pages: 773-782
- DOI
  10.1210/en.2012-1928
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23593027, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592786, KAKENHI-PROJECT-24592849, KAKENHI-PROJECT-24593112, KAKENHI-PROJECT-24593132, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25670793
[Journal Article] Roles of cathelicidin-related antimicrobial peptide in murine2013
- Author(s)
  Horibe K, Kobayashi Y, Takahashi N, Udagawa N(他4名)
- Journal Title
  
  Immunology
  
  Volume: 140 Pages: 344-351
- DOI
  10.1111/imm.12146
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24593112, KAKENHI-PROJECT-24593132, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25253097, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905
[Journal Article] Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone.2012
- Author(s)
  Harada S, Mizoguchi T, Kobayashi Y, Nakamichi Y, Takeda S, Sakai S, Takahashi F, Saito H, Yasuda H, Udagawa N, Suda T, Takahashi N.
- Journal Title
  
  J Bone Miner Res
  
  Volume: 27 Pages: 461-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] Wnt シグナルによる骨代謝制御2012
- Author(s)
  小林泰浩、上原俊介
- Journal Title
  
  日本抗加齢医学会雑誌
  
  Volume: 8 Pages: 719-725
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] positive cells in the subodontoblastic layer possess high potential to differentiate into hard tissue-forming2012
- Author(s)
  Hosoya A, Hiraga T, Ninomiya T, Yukita A, Yoshiba K, Yoshiba N, Takahashi M, Ito S, Nakamura H.
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: 137(6) Pages: 733-42
- DOI
  10.1007/s00418-012-0928-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22592172, KAKENHI-PROJECT-22791781, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-24592785, KAKENHI-PROJECT-24592786, KAKENHI-PROJECT-24592787, KAKENHI-PROJECT-24592863
[Journal Article] Wnt による骨代謝制御機構2012
- Author(s)
  小林泰浩
- Journal Title
  
  TheBone
  
  Volume: 26 Pages: 151-159
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] Wnt による破骨細胞の分化制御機構2012
- Author(s)
  Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N
- Journal Title
  
  細胞
  
  Volume: 24 Pages: 2176-2185
- DOI
  10.1002/adma.201103832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002007, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-24659833
[Journal Article] Polarized osteoclasts put marks tartrate-resistant acid phosphatase on dentin slices; A simple method for identifying polarized osteoclasts.2012
- Author(s)
  Nakayama T, et al
- Journal Title
  
  Bone
  
  Volume: 49 Pages: 1331-1339
- DOI
  10.1016/j.bone.2011.09.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792134
[Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012
- Author(s)
  Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N
- Journal Title
  
  J. Cell Sci
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Wnt シグナルによる骨代謝制御機構2012
- Author(s)
  小林泰浩
- Journal Title
  
  Clinical Calcium.
  
  Volume: 22 Pages: 1701-1706
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] 1alpha, 25-dihydroxy vitamin D3 regulates differentiation into osteoblasts in periodontal ligament2012
- Author(s)
  Chen YC, Ninomiya T, Hosoya A, Hiraga T, Miyazawa H, Nakamura H.1
- Journal Title
  
  Arch Oral Biol
  
  Volume: 57(5) Pages: 453-459
- DOI
  10.1016/j.archoralbio.2011.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-24592786
[Journal Article] UBC9 negatively regulates BMP-mediated osteoblastic differentiation in cultured cells2012
- Author(s)
  Yukita A, Hosoya A, Ito Y, Katagiri T, Asashima M, Nakamura H
- Journal Title
  
  Bone
  
  Volume: 50 Pages: 1092-1099
- DOI
  10.1016/j.bone.2012.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21241048, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-24592278, KAKENHI-PROJECT-24592785, KAKENHI-PROJECT-24592787
[Journal Article] Wnt5a-Ror2 シグナルを標的にした新規骨吸収阻害薬の開発2012
- Author(s)
  小林泰浩
- Journal Title
  
  ケミカルエンジニアリング
  
  Volume: 57 Pages: 921-925
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone.2012
- Author(s)
  Harada S et al.
- Journal Title
  
  J. Bone Miner. Res.
  
  Volume: 27 Pages: 461-473
- DOI
  10.1002/jbmr.555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135
[Journal Article] Lineage-committed osteoclast precursors circulate in blood and settle down into bone.2012
- Author(s)
  Muto, A, Mizoguchi, T, Udagawa, N., Ito, S, Kawahara, I, Abiko, Y, Arai, A., Harada, S., Kobayashi, Y., Nakamichi, Y, Penninger, JM, Noguchi, T, Takahashi, N.
- Journal Title
  
  J Bone MinerRes.Dec;
  
  Volume: 26 Pages: 2978-2990
- DOI
  10.1002/jbmr.490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-21390498, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390550, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-21592615, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-23792492
[Journal Article] Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in CSF-1^<op/op>mice2012
- Author(s)
  Nakamichi Y et al.
- Journal Title
  
  PNAS. Jun
  
  Volume: 109 Pages: 10006-1
- DOI
  10.1073/pnas.1207361109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24659833
[Journal Article] Wntによる骨代謝制御機構2012
- Author(s)
  小林泰浩
- Journal Title
  
  The Bone
  
  Volume: 26 Pages: 151-159
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012
- Author(s)
  Arai A et al.
- Journal Title
  
  J Cell Sci. Feb;
  
  Volume: 125 Pages: 2910-17
- DOI
  10.1242/jcs.099986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
[Journal Article] Nishita M, Marumo K, Martin TJ, Minami Y, Takahashi NWnt5a-Ror2 signaling betweenosteoblast-lineage cells and osteoclast precursors enhancesosteoclastgenesis.2012
- Author(s)
  Maeda, K., Kobayashi, Y., Udagawa, N., Uehara, S., Ishihara, A., Mizoguchi, T., Kikuchi, Y., Takada, I., Kato, S., Kani, S., Nishita, M., Marumo, K., Martin, T.J., Minami, Y., Takahashi, N.
- Journal Title
  
  Nat Med.
  
  Volume: (印刷中) Pages: 405-12
- DOI
  10.1038/nm.2653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390080, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PUBLICLY-22021039, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22790291, KAKENHI-PLANNED-23112007, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23650595, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-23792134, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
[Journal Article] c-Fos plays an essential role in theup-regulation of RANK expression in osteoclast precursors within the bone microenvironment.2012
- Author(s)
  Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N.
- Journal Title
  
  J Cell Sci
  
  Volume: 125 Pages: 2910-2917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] Tetracyclines Convert the Osteoclastic-Differentiation Pathway of Progenitor Cells To Produce Dendritic Cell-like Cells2012
- Author(s)
  Kinugawa S et al.
- Journal Title
  
  J Immunology
  
  Volume: 188 Pages: 1772-1781
- DOI
  10.4049/jimmunol.1101174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22792102, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792492, KAKENHI-PROJECT-24592786
[Journal Article] Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis.2012
- Author(s)
  Maeda K, Kobayashi Y (2), Mizoguchi T (6).
- Journal Title
  
  Nat Med
  
  Volume: 18 Pages: 405-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] Two distinct processes of bone-like tissue formation by dental pulp cells after tooth transplantation2012
- Author(s)
  Hosoya A et al.
- Journal Title
  
  Journal of Histochemistry & Cytochemistry
  
  Volume: 60 Pages: 861-73
- DOI
  10.1369/0022155412459741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-24592785, KAKENHI-PROJECT-24592787, KAKENHI-PROJECT-24592863
[Journal Article] 骨芽細胞系細胞と破骨細胞前駆細胞の間の Wnt5a-Ror2 シグナルは破骨細胞形成を亢進する2012
- Author(s)
  小林泰浩,前田和洋、高橋直之
- Journal Title
  
  実験医学
  
  Volume: 30 Pages: 1933-1936
- Data Source
  KAKENHI-PROJECT-23659972
[Journal Article] Role of heparan sulfate proteoglycans surrounding osteoblast lineage cells2012
- Author(s)
  Nakamura H, Yukita A, Ninomiya T, HosoyaA, Hiraga T.
- Journal Title
  
  J Oral Biosci
  
  Volume: 54(1) Pages: 43-47
- DOI
  10.1016/j.job.2012.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23659926
[Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals2011
- Author(s)
  Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
- Journal Title
  
  Front Biosci
  
  Volume: 16 Pages: 21-30
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21196156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659339
[Journal Article] Prostaglandin E(2) receptor EP(4)-selective agonist (ONO-4819) increases bone formation by modulating mesenchymal cell differentiation2011
- Author(s)
  Ninomiya T, Hosoya A, Hiraga T, Koide M, Yamaguchi K, Oida H, Arai Y, Sahara N, Nakamura H, Ozawa H.
- Journal Title
  
  Eur J Pharmcol
  
  Volume: 650(1) Pages: 396-402
- DOI
  10.1016/j.ejphar.2010.10.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22792102, KAKENHI-PROJECT-23659883
[Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices-A simple method for identifying polarized osteoclasts-2011
- Author(s)
  Nakayama T, Mizoguchi T, Uehara S, Yamashita T, Kawahara I, Kobayashi Y, Moriyama Y, Kurihara S, Sahara N, Ozawa H, Udagawa N, Takahashi N
- Journal Title
  
  Bone
  
  Volume: 49(6) Pages: 1331-1339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659339
[Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices-a simple method for identifying polarized osteoclasts2011
- Author(s)
  Nakayama T, Mizoguchi T, Uehara S, Yamashita T, Kawahara I, Kobayashi Y, Moriyama Y, Kurihara S, Sahara N, Ozawa H, Udagawa N, Takahashi N
- Journal Title
  
  Bone
  
  Volume: 49 Pages: 1331-1339
- URL
  http://dx.doi.org/10.1016/j.bone.2011.09.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Identification of osteoclasts in culture.2011
- Author(s)
  Udagawa N, et al
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 690 Pages: 273-284
- DOI
  10.1007/978-1-60761-962-8_18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339
[Journal Article] Prostaglandin E(2) receptor EP(4)-selective agonist(ONO-4819) increases bone formation by modulating mesenchymal cell differentiation2011
- Author(s)
  Ninomiya T, Hosoya A, Hiraga T, Koide M, Yamaguchi K, Oida H, Arai Y, Sahara N, Nakamura H, Ozawa H
- Journal Title
  
  Eur. J. Pharmacol
  
  Volume: 650 Pages: 396-402
- URL
  http://dx.doi.org/10.1016/j.ejphar.2010.10.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals2011
- Author(s)
  Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
- Journal Title
  
  Front. Biosci
  
  Volume: 16 Pages: 21-30
- URL
  http://dx.doi.org/10.2741/3673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals.2011
- Author(s)
  Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
- Journal Title
  
  Front Biosci
  
  Volume: 16 Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390351
[Journal Article] Potential of periodontal ligament cells to regenerate alveolar bone.2010
- Author(s)
  Hosoya A, et al.
- Journal Title
  
  J Oral Biosci
  
  Volume: 52 Pages: 72-80
- NAID
  10027105411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Potential of Periodontal Ligament Cells to Regenerate Alveolar Bone2010
- Author(s)
  Hosoya A, Ninomiya T, Hiraga T, Yoshiba K, Yoshiba N, Kasahara E, Ozawa H, Nakamura H.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 52(2) Issue: 2 Pages: 72-80
- DOI
  10.2330/joralbiosci.52.72
- NAID
  10027105411
- ISSN
  1349-0079, 1880-3865
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Localization of Thy-1-positive cells in the perichondrium during endochondral ossification.2010
- Author(s)
  Nakamura H, Yukita A, Ninomiya T, Hosoya A, Hiraga T, Ozawa H.
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 58(5)
- DOI
  10.1369/jhc.2010.955393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Immunohistochemical localization of cytokeratins in the junctional region of ectoderm and endoderm.2010
- Author(s)
  Hosoya A, et al.
- Journal Title
  
  Anat Rec (Hoboken)
  
  Volume: 293 Pages: 1864-1872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Zoledronic acid delays wound healing of the tooth extraction socket in mice : Insights into the pathogenesis of bisphosphonate-related osteonecrosis of the jaw.2010
- Author(s)
  Kobayashi Y, et al.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 28 Pages: 165-175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Zoledronic acid delays wound healing of the tooth extraction socket, inhibits oral epithelial cell migration, and promotes proliferation and adhesion to hydroxyapatite of oral bacteria, without causing osteonecrosis of the jaw, in mice.2010
- Author(s)
  Kobayashi Y, Hiraga T, Ueda A, Wang L, Matsumoto-Nakano M, Hata K, Yatani H, Yoneda T.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 28(2) Pages: 165-75
- DOI
  10.1007/s00774-009-0128-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Administration of the bisphosphonate zoledronic acid during tooth development inhibits tooth eruption and formation and induces dental abnormalities in rats2010
- Author(s)
  Hiraga T, Ninomiya T, Hosoya A, Nakamura H.
- Journal Title
  
  Calcif. Tissue Int
  
  Volume: 86(6) Pages: 502-10
- DOI
  10.1007/s00223-010-9366-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551
[Journal Article] Zoledronic acid delays wound healing of the tooth extraction socket in mice : Insights into the pathogenesis of bisphosphonate-related osteonecrosis of the jaw.2010
- Author(s)
  Kobayashi Y, et al.
- Journal Title
  
  J Bone Miner Metab (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in mice2010
- Author(s)
  Lee JW, Kobayashi Y, Nakamichi Y, Udagawa N, Takahashi N, Im NK, Seo HJ, Jeon WB, Yonezawa T, Cha BY, Woo JT.
- Journal Title
  
  Biochem. Pharmacol
  
  Volume: 80 Pages: 352-361
- URL
  http://dx.doi.org/10.1016/j.bcp.2010.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Expression of p^<63> during early craniofacial development of the mouse embryo.2009
- Author(s)
  Hosoya A, et al.
- Journal Title
  
  Dev Reprod 13
  
  Pages: 89-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Action of RANKL and OPG for osteoclastogenesis.2009
- Author(s)
  Kobayashi Y, et al.
- Journal Title
  
  Crit Rew Eukaryot Gene Expr 19
  
  Pages: 61-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Formation of bone-like mineralized matrix by periodontal ligament cells in vivo: a morphological study in rats.2009
- Author(s)
  Hiraga T, Ninomiya T, Hosoya A, Takahashi M, Nakamura H.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 27(2) Pages: 149-57
- DOI
  10.1007/s00774-009-0039-9
- NAID
  10025336621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505
[Journal Article] Action of RANKL and OPG for osteoclastogenesis2009
- Author(s)
  Kobayashi Y, Udagawa N, Takahashi N
- Journal Title
  
  Crit. Rev. Eukaryot. Gene Expr
  
  Volume: 19 Pages: 61-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390551
[Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2009
- Author(s)
  Mizoguchi T, Muto A, Udagawa N, Arai A, Yamashita T, Hosoya A, Ninomiya T, Nakamura H, Yamamoto Y, Kinugawa S, Nakamura M, Nakamichi Y, Kobayashi Y, Nagasawa S, Oda K, Tanaka H, Tagaya M, Penninger JM, Ito M, Takahashi N.
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 184(4) Pages: 541-54
- DOI
  10.1083/jcb.200806139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378
[Journal Article] The action of RANKL and OPG for osteoclastogenesis2008
- Author(s)
  Yasuhiro Kobayashi
- Journal Title
  
  Critical review in Eukaryotic gene expression. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Roles of Wnt signaling in bone formation and resorption2008
- Author(s)
  Yasuhiro Kobayashi, et. al.
- Journal Title
  
  The Japanese Dental Science Review (In press)(掲載確定)
- NAID
  10023922839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Roles of Wnt signaling in bone formation and resorption2008
- Author(s)
  Yasuhiro Kobayashi, et. al.
- Journal Title
  
  The Japanese Dental Science Review (In press)
- NAID
  10023922839
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] The action of RANKL and OPG for osteoclastogenesis2008
- Author(s)
  Yasuhiro Kobayashi, et. al.
- Journal Title
  
  Critical Review in Eukaryotic gene expression (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Roles of Wnt signaling in bone formation and resorption.2008
- Author(s)
  Yasuhiro Kobayashi
- Journal Title
  
  The Japanese Dental Science Review (in press)
- NAID
  10023922839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Roles of Wnt signaling in bone formation and resorption2008
- Author(s)
  Yasuhiro Kobayashi
- Journal Title
  
  The Japanese Dental Science Review (In press)(掲載確定)
- NAID
  10023922839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659618
[Journal Article] 歯槽骨のリモデリング機構2007
- Author(s)
  小林泰浩, 他
- Journal Title
  
  Clinical Calcium 17
  
  Pages: 69-75
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] 下垂体ホルモンTSHとFSHによる骨代謝調節2007
- Author(s)
  小林泰浩
- Journal Title
  
  The Bone 21
  
  Pages: 93-98
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Regulation of bone metabolism by TSH and FSH2007
- Author(s)
  Yasuhiro Kobayashi
- Journal Title
  
  The Bone 21
  
  Pages: 93-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Hard tissue formation in subcutaneously transplanted rat dental pulp2007
- Author(s)
  A.Hosoya
- Journal Title
  
  J Dent Res 86
  
  Pages: 463-468
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592019
[Journal Article] Mechanisms of alveolar bone remodeling2007
- Author(s)
  Yasuhiro Kobayashi
- Journal Title
  
  Clinical Calcium 17
  
  Pages: 69-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Hard tissue formation in subcutaneously transplanted rat dental pulp.2007
- Author(s)
  A. Hosoya
- Journal Title
  
  J Dent Res. 86
  
  Pages: 463-468
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592019
[Journal Article] 歯槽骨のリモデリング機構2007
- Author(s)
  小林泰浩
- Journal Title
  
  Clinical Calcium 17・(2)
  
  Pages: 69-76
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] 歯槽骨のリモデリング機構2007
- Author(s)
  小林泰浩
- Journal Title
  
  Clinical Calcium 17・(2)
  
  Pages: 69-76
- Data Source
  KAKENHI-PROJECT-18659618
[Journal Article] 下垂体ホルモンTSHとFSHによる骨代謝調節2007
- Author(s)
  小林泰浩
- Journal Title
  
  The Bone 21
  
  Pages: 93-98
- Data Source
  KAKENHI-PROJECT-18659618
[Journal Article] The pathophysiology of osteoporosis/osteopenia in gene mutant mice2006
- Author(s)
  Yasuhiro Kobayashi
- Journal Title
  
  Clinical Calcium 16
  
  Pages: 311-318
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] 骨量減少症を発症する遺伝子改変マウス2006
- Author(s)
  小林泰浩, 他
- Journal Title
  
  Clinical Calcium 16
  
  Pages: 87-93
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Journal Article] Cyclic AMP/protein kinase A signals enhance osteoclastic differentiation through TAK1 in osteoclast precursors.2005
- Author(s)
  Kobayashi Y et al.
- Journal Title
  
  J Biol Chem (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390641
[Journal Article] Prostaglandin E_2 receptors EP2 and EP4 are down-regulated during differentiation of mouse osteoclasts from their precursors.2005
- Author(s)
  Kobayashi Y, et al.
- Journal Title
  
  J Biol Chem (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390641
[Journal Article] Prostaglandin E_2 receptors EP2 and EP4 are down-regulated during differentiation of mouse osteoclasts from their precursors.2005
- Author(s)
  Kobayashi Y et al.
- Journal Title
  
  J Biol Chem (in press)
- Data Source
  KAKENHI-PROJECT-15659445
[Journal Article] Cyclic AMP/protein kinase A signals enhance osteoclastic differentiation through TAK1 in osteoclast precursors.2005
- Author(s)
  Kobayashi Y et al.
- Journal Title
  
  J Biol Chem (in press)
- Data Source
  KAKENHI-PROJECT-15659445
[Journal Article] Prostaglandin E_2 receptors EP2 and EP4 are down-regulated during differentiation of mouse osteoclasts from their precursors.2005
- Author(s)
  Kobayashi Y et al.
- Journal Title
  
  J Biol Chem (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390641
[Journal Article] Prostaglandin E_2 receptors EP2 and EP4 are down-regulated during differentiation of mouse osteoclasts from their precursors.2005
- Author(s)
  Kobayashi Y et al.
- Journal Title
  
  J Biol Chem (in press)
- Data Source
  KAKENHI-PROJECT-12137209
[Journal Article] Prostaglandin E_2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAKI.2005
- Author(s)
  Kobayashi Y, et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 11395-11403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390641
[Journal Article] Cyclic AMP/protein kinase A signals enhance osteoclastic differentiation through TAK1 in osteoclast precursors.2005
- Author(s)
  Kobayashi Y et al.
- Journal Title
  
  J Biol Chem (in press)
- Data Source
  KAKENHI-PROJECT-12137209
[Journal Article] Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in CSF-1^<op/op> mice
- Author(s)
  Nakamichi Y, Mizoguchi T, Arai A, Kobayashi Y, Sato M, Penninger JM, Yasuda H, Kato S, DeLuca HF, Suda T, Udagawa N, Takahashi N
- Journal Title
  
  Proc Natl Acad Sci UAS
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659339
[Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment
- Author(s)
  Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N
- Journal Title
  
  J Cell Science
  
  Volume: (In press)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22454522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659339
[Journal Article] Regulatory mechanism of osteoclastogenesis by Wnt signaling.
- Author(s)
  Kobayashi Y, Maeda K, Uehara S, Yamashita T, Takahashi N
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: (In press)
- NAID
  130004943807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390351
[Journal Article] Regulatory mechanism of osteoclastogenesis by Wnt signaling
- Author(s)
  Kobayashi Y, Maeda K, Uehara S, Yamashita T, Takahashi N
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: (In press)
- NAID
  130004943807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659339
[Patent] タンパク質、破骨細胞分化阻害剤、炎症性骨破壊治療薬、遺伝子、組み替えベクター、及びタンパク質の製造方法2007
- Inventor(s)
  小林泰浩
- Industrial Property Rights Holder
  学校法人松本歯科大学
- Industrial Property Number
  2007-240015
- Filing Date
  2007-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] Rho-Pkn3-c-Src pathways promote the bone-resorbing activity of osteoclasts under Wnt5a-Ror2 signaling pathways2018
- Author(s)
  Uehara S, Yamashita T, Murakami K, Koide M, Nakamura T, Kato S, Udagawa N, Takahashi N, Kobayashi Y
- Organizer
  第15回Bone Biology Forum
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] 破骨細胞に発現するSiglec-15の骨代謝カップリングにおける重要性2018
- Author(s)
  宇田川信之、上原俊介、小出雅則、荒井敦、溝口利英、中村美どり、小林泰浩、高橋直之、福田千恵、津田英資
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] Wnt5a-Ror2シグナルによるPkn3を介した破骨細胞機能促進2018
- Author(s)
  上原俊介，村上康平，山下照仁，小出雅則，高橋直之，宇田川信之，小林泰浩
- Organizer
  第３回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] Wnt5a-Ror2シグナルは、Daam2-Rho-Pkn3-c-Src経路を介して破骨細胞の骨吸収を促進する2018
- Author(s)
  上原俊介，山下照仁，村上康平，小出雅則，中村貴，加藤茂明，宇田川信之，高橋直之，小林泰浩
- Organizer
  第36回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] Pkn3阻害薬による破骨細胞の骨吸収制御2018
- Author(s)
  上原俊介，山下照仁，小出雅則，村上康平，中村貴，加藤茂明，宇田川信之，高橋直之，小林泰浩
- Organizer
  第４回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] 骨髄間葉系幹細胞は低レベルにRunx2を発現している2018
- Author(s)
  溝口利英、楊孟雨、荒井敦、小林泰浩、宇田川信之、高橋直之
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-16K11798
[Presentation] 破骨細胞に発現するSiglec-15の骨代謝カップリングにおける重要性2017
- Author(s)
  20.宇田川信之, 上原俊介, 小出雅則, 荒井敦, 溝口利英, 中村美どり,小林泰浩, 高橋直之, 福田千恵, 津田英資
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] Ror2-Rho-Pkn3シグナルは破骨細胞の骨吸収活性を促進する2017
- Author(s)
  上原俊介，山下照仁，宇田川信之，高橋直之，小林泰浩
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] 有袋類や単孔類のカルシトニンは強力な生物活性を持つ2017
- Author(s)
  山下照仁，宇田川信之，山内広世，鈴木信雄，上原俊介，小林泰浩，高橋直之
- Organizer
  日本骨代謝学会学術集会 (第35回)
- Place of Presentation
  ホテル日航福岡(福岡県)
- Year and Date
  2017-07-27
- Data Source
  KAKENHI-PROJECT-15K15688
[Presentation] 髄間葉系幹細胞は低レベルにRunx2を発現している2017
- Author(s)
  溝口利英, 楊孟雨, 荒井敦, 小林泰浩, 宇田川信之, 高橋直之
- Organizer
  第3回日本骨免疫学会ウインターセミナー
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] Wnt5a-Ror2シグナルによる骨吸収活性調節の病態モデルにおける役割2017
- Author(s)
  上原俊介，山下照仁，中村貴，加藤茂明，宇田川信之，高橋直之，小林泰浩
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] 破骨細胞におけるRor2シグナルは炎症性骨破壊を増悪する2017
- Author(s)
  上原俊介，山下照仁，中村貴，加藤茂明，宇田川信之，高橋直之，小林泰浩
- Organizer
  第２回日本骨免疫学会ウィンターセミナー
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] Vdr in osteoblast-lineage cells primarily mediates a 1α,25(OH)2D3 derivative-induced increase in bone mass by suppressing bone resorption2017
- Author(s)
  Nakamichi, Y., Udagawa, N., Horibe, K., Mizoguchi, T., Yamamoto, Y., Nakamura, T., Hosoya, A., Kato, S., Suda, T., and Takahashi, N.
- Organizer
  20th Vitamin D Workshop, March, 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04374
[Presentation] Wnt5a-Ror2 signaling promotes osteoclast function via Daam2-Rho-Pkn3 pathways.2017
- Author(s)
  Uehara S, Udagawa N, Yamashita T, Murakami K, Takahashi N and Kobayashi Y
- Organizer
  第65回国際歯科研究学会日本部会総会・学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] VDR in osteoblast-lineage cells primarily mediates a 1a,25(OH)2D3 derivative-induced increase in bone mass by suppressing bone resorption.2017
- Author(s)
  Nakamichi Y, Udagawa N, Horibe K, Mizoguchi T, Yamamoto Y, Nakamura T, Hosoya A, Kato S, Suda T, and Takahashi N.
- Organizer
  第20回ビタミンDワークショップ
- Place of Presentation
  Rosen Centre (米国フロリダ州オランド)
- Year and Date
  2017-03-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11493
[Presentation] Wnt5a-Ror2 シグナルは Rho-Pkn3-c-Src 経路を介して破骨細胞の骨吸収活性を制御する2016
- Author(s)
  上原俊介、山下照仁、宇田川信之、高橋直之、小林泰浩
- Organizer
  第５８回日本歯科基礎医学会学術大会
- Place of Presentation
  札幌　札幌コンベンションセンター
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] カテプシンＫ阻害剤投与は、オステオプロテゲリン欠損マウスにおいて、骨吸収抑制と共に骨形成促進作用を示す2016
- Author(s)
  宇田川信之、中村美どり、中道裕子、溝口利英、小林泰浩、高橋直之
- Organizer
  第83回松本歯科大学学会
- Place of Presentation
  松本歯科大学　(長野県・塩尻市)
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] カテプシンＫ阻害剤投与は、オステオプロテゲリン欠損マウスにおいて、骨吸収抑制と共に骨形成促進作用を示す2016
- Author(s)
  中村美どり、中道裕子、溝口利英、小林泰浩、高橋直之、宇田川信之
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場　(大阪府・大阪市)
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] Wnt5a-Ror2シグナルにより活性化されるRor-Pkn3経路はc-Srcを介して骨吸収を調節する。2016
- Author(s)
  上原俊介、山下照仁、中村　貴、加藤茂明、宇田川信之、高橋直之、小林泰浩
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場、大阪市北区中之島
- Year and Date
  2016-07-21
- Data Source
  KAKENHI-PROJECT-16H05144
[Presentation] Pkn3はRor2-Rhoシグナルの下流でc-Srcを介して破骨細胞の骨吸収を制御する2016
- Author(s)
  上原俊介、山下照仁、中村貴、加藤茂明、宇田川信之、高橋直之、小林泰浩
- Organizer
  第２回日本骨免疫学会
- Place of Presentation
  沖縄　ホテルモントレ―
- Year and Date
  2016-07-06
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] PTHアナボリック作用に対する骨髄間葉系幹細胞の寄与2016
- Author(s)
  楊孟雨、溝口利英、宇田川信之、松尾光一、小守壽文、森石武史、小林泰浩、高橋直之
- Organizer
  第34回日本骨代謝学会
- Place of Presentation
  大阪国際会議場　(大阪府・大阪市)
- Year and Date
  2016-07-22
- Data Source
  KAKENHI-PROJECT-26462826
[Presentation] Wnt5a-Ror2シグナルにより活性化されるRho-Pkn3経路はc-Srcを介して骨吸収を調節する2016
- Author(s)
  上原俊介、山下照仁、中村貴、加藤茂明、宇田川信之、高橋直之、小林泰浩
- Organizer
  第３４回日本骨代謝学会学術集会
- Place of Presentation
  大阪　大阪国際会議場
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K11494
[Presentation] Rho-Pkn3 pathway regulates the bone-resorbing activity of osteoclasts under Wnt5a-Ror2 signaling2015
- Author(s)
  Uehara S, Mukai H, Yamashita T, Nakamura T, Kato S, Kikuchi A, Nishita M, Minami Y, Udagawa N, Takahashi N, Kobayashi Y
- Organizer
  第37回アメリカ骨代謝学会(ASBMR)
- Place of Presentation
  ワシントン州コンベンションセンター　アメリカ　シアトル
- Year and Date
  2015-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462904
[Presentation] Rho-Pkn3 Pathway Regulates the Bone-resorbing Activity of Osteoclasts under Wnt5a-Ror22015
- Author(s)
  Uehara S, Mukai H, Yamashita T, Nakamura T, Kato S, Kikuchi A, Nishita M, Minami Y, Udagawa N, Takahashi N, Kobayashi Y
- Organizer
  米国骨代謝学会（ASBMR）
- Place of Presentation
  ワシントンステートコンベンションセンター（米国ワシントン州）
- Year and Date
  2015-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15688
[Presentation] Wnt5a-Ror2シグナルの下流で骨吸収機能を調節するPKN32015
- Author(s)
  上原俊介，山下照仁，中村貴，加藤茂明，宇田川信之，高橋直之，小林泰浩
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル　東京　新宿
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-25462904
[Presentation] オステオプロテゲリン結合サイトカインであるTRAILの骨組織における役割2015
- Author(s)
  宇田川信之, 中村美どり，中道裕子，小出雅則，小林泰浩，高橋直之
- Organizer
  日本骨免疫学会（第１回）
- Place of Presentation
  ブリーズベイマリーナ（沖縄県宮古島市）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K15688
[Presentation] Wnt5a-Ror2 signal regulates function of osteoclasts through Daam2-Rho pathway2014
- Author(s)
  Uehara S, Ishihara A, Maeda K, Yamashita T, Nakamura T, Kato S, Kikuchi A, Nishita M, Minami Y, Udagawa N, Takahashi N, Kobayashi Y
- Organizer
  第5回International conference on osteoimmunology
- Place of Presentation
  へロナリゾート　ギリシャ　コス島
- Year and Date
  2014-06-16
- Data Source
  KAKENHI-PROJECT-25462904
[Presentation] Wnt5a-Ror2シグナルは、Daam2-Rhoを介して骨吸収機能を促進する2014
- Author(s)
  上原俊介、山下照仁、中村貴、加藤茂明、宇田川信之、高橋直之、小林泰浩
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル　東京　新宿
- Year and Date
  2014-07-28
- Data Source
  KAKENHI-PROJECT-25462904
[Presentation] Wnt5a enhances Wnt/beta-catenin signaling through the up-regulation of Lrp5/6 during osteogenesis2013
- Author(s)
  Okamoto M, UdagawaN, Yamashita T, Uehara S, Kato H, Saito N, Minami Y, Takahashi N, Kobayashi Y
- Organizer
  2013　米国骨代謝学会
- Place of Presentation
  Baltimore　Convention Center, USA
- Data Source
  KAKENHI-PROJECT-25293423
[Presentation] Roles Wnt5a-Ror2 signals in bone resorption2012
- Author(s)
  Kobayashi Yasuhiro
- Organizer
  2012年韓国骨代謝学会
- Place of Presentation
  san Medical Center (ソウル、韓国)
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23659972
[Presentation] Wnt5a-Ror2 シグナルのよる破骨細胞の分化と機能の制御機構2012
- Author(s)
  小林泰浩
- Organizer
  東北大学大学院セミナー
- Place of Presentation
  東北大学歯学部(仙台)
- Year and Date
  2012-09-13
- Data Source
  KAKENHI-PROJECT-23659972
[Presentation] Wnt5a-Ror2シグナルによる破骨細胞分化制御機構2012
- Author(s)
  小林泰浩
- Organizer
  第10回口腔医科学フロンティア学術集会
- Place of Presentation
  大阪
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Wnt5a-Ror2シグナルによる破骨細胞分化制御機構.2012
- Author(s)
  小林　泰浩
- Organizer
  第10回口腔医科学フロンティア学術集会(招待講演)
- Place of Presentation
  大阪大学歯学部（吹田市）
- Data Source
  KAKENHI-PROJECT-23659972
[Presentation] Wnt5a-Ror2 シグナルのよる破骨細胞分化制御機構2012
- Author(s)
  小林泰浩
- Organizer
  奥羽大学歯学部
- Place of Presentation
  郡山
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-23659972
[Presentation] Wnt5a-Ror2シグナルによる破骨細胞分化制御機構2012
- Author(s)
  小林泰浩
- Organizer
  第10回口腔医科学フロンティア学術集会
- Place of Presentation
  大阪大学・歯学部(吹田市)
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Wnt5aはRANKの発現を亢進し、破骨細胞分化を促進する2010
- Author(s)
  小林泰浩
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  京王プラホテル、東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21659478
[Presentation] Wnt5aはRANKの発現を亢進し、破骨細胞分化を促進する2010
- Author(s)
  小林泰浩, 前田和洋、上原俊介、高田伊知郎、加藤茂明、丸毛啓史、宇田川信之、高橋直之
- Organizer
  第28回日本骨代謝学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] 漢方牛蒡子由来のアルクチゲニンは破骨細胞の機能と分化を抑制する2010
- Author(s)
  山下照仁、上原俊介、小林泰浩、宇田川信之、高橋直之
- Organizer
  第28回日本骨代謝学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Ror2-mediated noncanonical Wnt signaling enhances RANKL-induced osteoclast formation in physiological and pathological conditions2010
- Author(s)
  Kobayashi Y, et al
- Organizer
  3^<rd> International conference on osteoimmun ology
- Place of Presentation
  Santorini, Greece
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Wntシグナルによる破骨細胞分化調節機構の解析2010
- Author(s)
  小林泰浩、溝口利英、上原俊介、高橋直之、宇田川信之
- Organizer
  第71回松本歯科大学学会例会
- Place of Presentation
  塩尻
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Ror2-mediated noncanonical Wnt signaling stimulates physiological and pathological osteoclastogenesis in a cell autonomous manner2009
- Author(s)
  小林泰浩
- Organizer
  第6回 Bone Biology Forum
- Place of Presentation
  帝人富士教育研修所
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21659478
[Presentation] 炎症性骨疾患におけるWntシグナルの役割2009
- Author(s)
  小林泰浩
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Ror2-mediated noncanonical Wnt signaling stimulates physiological and pathological osteoclastogenesis in a cell autonomous manner2009
- Author(s)
  小林泰浩
- Organizer
  第6回 Bone Biology Forum
- Place of Presentation
  帝人富士教育研修所
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Ror2-mediated noncanonical Wnt signaling enhances RANKL-induced osteoclast formation in physiological and pathological conditions2009
- Author(s)
  小林泰浩
- Organizer
  第26回内藤カンファレンスOsteobiology
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] 炎症性骨疾患におけるWntシグナルの役割2009
- Author(s)
  小林泰浩
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-21659478
[Presentation] Ror2-mediated noncanonical Wnt signaling stimulates physiological and pathological osteoclastogenesis in a cell autonomous manner2009
- Author(s)
  Kobayashi Y
- Organizer
  第6回Bone Biology Forum
- Place of Presentation
  裾野
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Treatment with bisphosphonate during tooth development inhibits tooth formation and eruption, and induces odontomas.2009
- Author(s)
  Hiraga T, Ninomiya T, Hosoya A, Nakamura H.
- Organizer
  31st Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Denver, Colorado, USA
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-21390505
[Presentation] Ror2-mediated noncanonical Wnt signaling enhances RANKL-induced osteoclast formation in physiological and pathological conditions2009
- Author(s)
  小林泰浩
- Organizer
  第26回内藤カンファレンスOsteobiology
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21659478
[Presentation] 炎症性骨疾患におけるWntの役割2009
- Author(s)
  小林泰浩
- Organizer
  第27回日本骨代謝学会、ミニシンポジウムOsteoimmunology 11
- Place of Presentation
  大阪
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-21390551
[Presentation] Roles of Wnt signaling in bone formation and resorption.2007
- Author(s)
  Y. Kobayashi
- Organizer
  The Japanese Society for Bone and Mineral Research
- Place of Presentation
  Oosaka Convention Center
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592019
[Presentation] Wntによる破骨細胞の分化制御機構2007
- Author(s)
  小林泰浩
- Organizer
  第66回日本矯正歯科学会大会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] Wntによる破骨細胞分化調節機構2007
- Author(s)
  小林泰浩
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592019
[Presentation] Wnt regulates osteoclast differentiaion2007
- Author(s)
  Yasuhiro Kobayashi, et. al.
- Organizer
  The 66th annual meeting of the Japanese orthodontic society
- Place of Presentation
  Osaka international convention center
- Year and Date
  2007-09-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] Wntによる破骨細胞分化調節機構2007
- Author(s)
  小林泰浩
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-18659618
[Presentation] Wntによる破骨細胞分化調節機構2007
- Author(s)
  小林泰浩
- Organizer
  第25回日本骨代謝学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] Wntによる破骨細胞分化の制御機構2007
- Author(s)
  小林泰浩, 他
- Organizer
  第66回日本矯正歯科学会大会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-09-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] Wntによる破骨細胞の分化制御機構2007
- Author(s)
  小林泰浩
- Organizer
  第66回日本矯正歯科学会大会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-18659618
[Presentation] Wnts regulate osteoclast differentiation.2007
- Author(s)
  Yasuhiro Kobayashi
- Organizer
  The 25th Annual meeting of the Japanese society for bone and mineral research
- Place of Presentation
  Osaka international convention center
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] Wntによる破骨細胞分化制御機構2007
- Author(s)
  小林泰浩, 他
- Organizer
  第25回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390557
[Presentation] Wnt5a-Ror2 signals boosts bone destruction in arthritis
- Author(s)
  Kobayashi Y et al.
- Organizer
  1st Asia-pacific bone and mineral research meeting, 22nd Annual scientific meeting Austrian & New Zealand bone & mineral Society
- Place of Presentation
  Perth, Australia
- Data Source
  KAKENHI-PROJECT-21390505
[Presentation] 破骨細胞の機能を制御するWnt5a-Ror2シグナルによるRho活性化
- Author(s)
  上原俊介、山下照仁、宇田川信之、高橋直之、小林泰浩
- Organizer
  第55回歯科基礎医学会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Data Source
  KAKENHI-PROJECT-25462904
[Presentation] Wnt5a-Ror2　signal regulates　osteoclast polarization through Daam2 and Rho
- Author(s)
  Uehara　S, Ishihara A, Maeda K, Yamashita T, Nakamura T, Imai Y, Kato S, Kikuchi A, Nishita M, Minami Y, Udagawa N, Takahashi N, Kobayashi Y
- Organizer
  国際骨代謝学会(IBMS)・日本骨代謝学会第2回合同学術集会
- Place of Presentation
  神戸コンベンションセンター（神戸市）
- Data Source
  KAKENHI-PROJECT-25462904
[Presentation] Origin of bone-like tissues in dental pulp after tooth transplantation.
- Author(s)
  Hosoya A et al.
- Organizer
  The 60th Annual Meeting of Japanese Association for Dental Research
- Place of Presentation
  新潟コンベンションセンター（新潟）
- Data Source
  KAKENHI-PROJECT-21390505
[Presentation] Wnt5a-Ror2シグナルによる破骨細胞分化制御機構
- Author(s)
  小林　泰浩
- Organizer
  第54回歯科基礎医学会学術集会「サテライトシンポジウム６」
- Place of Presentation
  奥羽大学歯学部（郡山）
- Invited
- Data Source
  KAKENHI-PROJECT-23659972
[Presentation] Wnt5a-Ror2シグナルによる破骨細胞分化制御機構
- Author(s)
  小林　泰浩ら
- Organizer
  第54回歯科基礎医学会学術大会
- Place of Presentation
  奥羽大学（福島県）
- Data Source
  KAKENHI-PROJECT-21390505
[Presentation] 破骨細胞の分化に必須な因子NFATc1の転写活性を抑制するアルクチゲニンの作用メカニズム
- Author(s)
  山下照仁，李峰，上原俊介，小林泰浩，宇田川信之，門田重利，高橋直之
- Organizer
  第76回松本歯科大学学会例会
- Place of Presentation
  松本歯科大学（塩尻市）
- Data Source
  KAKENHI-PROJECT-25462904
[Presentation] Wnt5a enhances Wnt/-catenin signaling through the up-regulation of Lrp5/6 during osteogenesis
- Author(s)
  Okamoto M, Udagawa N, Yamashita T, Uehara S, Kato H, Saito N, Minami Y, Takahashi N and Kobayashi Y
- Organizer
  第35回アメリカ骨代謝学会(ASBMR)
- Place of Presentation
  ボルチモアコンベンションセンター（アメリカ　メリーランド州ボルチモア）
- Data Source
  KAKENHI-PROJECT-25462904
[Presentation] Roles of Wnt5a-Ror2 signals in bone resorption.
- Author(s)
  Kobayashi Yasuhiro
- Organizer
  2012 韓国骨代謝学会学術集会
- Place of Presentation
  Asan Medical Center (ソウル, 韓国）
- Invited
- Data Source
  KAKENHI-PROJECT-23659972
[Presentation] Wnt5a-Ror2 シグナルによる破骨細胞の分化と機能の制御機構
- Author(s)
  小林　泰浩
- Organizer
  東北大学大学院セミナー
- Place of Presentation
  東北大学歯学部（仙台）
- Invited
- Data Source
  KAKENHI-PROJECT-23659972
[Presentation] Wnt5a-Ror2シグナルは関節炎に伴う骨破壊を増悪する
- Author(s)
  小林　泰浩ら
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-21390505

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74. KOBAYASHI Shinsuke

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86. KIM YOONG AHM

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88. 山本雅之

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105. 齋藤暁子

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106. 齋藤卓

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107. 加藤博之

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kobayashi yasuhiro 小林 泰浩

KOBAYASHI Yasuhiro 小林 泰浩

Research Projects

Research Products

Co-Researchers

Identification of novel dental pulp stem cells and analysis of their regulatory mechanisms of differentiationOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

プロテインキナーゼN3による破骨細胞機能制御機構の解明とその臨床応用Ongoing

Principal Investigator

Project Period (FY)

Research Category

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骨代謝―脱共役機構の統合的解明を起点にした新たな骨および歯周疾患治療薬の開発Ongoing

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幹細胞の分化を司る組織常在型Ｍ３マクロファージとそのマスター転写因子の同定Principal InvestigatorOngoing

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Analysis of reparative dentin formation regulated by dental pulp stem cells using a fate mapping approachOngoing

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Wntシグナルネットワークを基盤とした歯槽骨代謝回転制御法の開発Principal InvestigatorOngoing

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kobayashi yasuhiro 小林泰浩

KOBAYASHI Yasuhiro 小林泰浩