Kakino Akemi 垣野明美

… Alternative Names

KAKINO Akemi 垣野明美

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Researcher Number	00534637
Other IDs
Affiliation (Current)	2025: 信州大学, 学術研究院医学系, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 信州大学, 学術研究院医学系, 助教 2014 – 2017: 信州大学, 先鋭領域融合研究群バイオメディカル研究所, 助教(特定雇用) 2015: 信州大学, 先鋭領域融合研究群バイオメディカル研究所, 助教 2013: 独立行政法人国立循環器病研究センター, 研究所, 研究員
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / General pharmacology Except Principal Investigator General pharmacology / Basic Section 59020:Sports sciences-related / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 52010:General internal medicine-related / Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator 酸化LDL / アディポネクチン / 変性LDL / 肺高血圧症 / ゲノム編集ラット / 肺高血圧 / LOX-1 / 脳梗塞 / 動脈硬化 / 酸化LDL受容体 … More Except Principal Investigator … More LOX-1 / 受容体 / リポ蛋白質 / 尿酸結晶 / NETosis / インフラマソーム / 依存性 / 高脂肪食 / 摂食 / 変性HDL-C / 冠動脈硬化症 / 変性HDLコレステロール / 凝固因子 / DIC / 血液 / 心血管 / DAMPs / 循環器・高血圧 / 複合体形成 / 変性LDL受容体 / クロストーク / GPCR Less

高尿酸血症から痛風発作に至る生体分子機構の研究
- Principal Investigator
  
  沢村達也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Shinshu University
骨格筋の新機能としての老廃物除去機能を解明する
- Principal Investigator
  
  細田洋司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Shinshu University
血管機能異常による高脂肪食依存性機構の解明
- Principal Investigator
  
  沢村達也
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Shinshu University
Elucidation of the significance of endothelial function molecule in the pathophysiology of pulmonary arterial hypertensionPrincipal Investigator
- Principal Investigator
  
  Kakino Akemi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Shinshu University
The risk assessment of coronary artery diseas by a novel method to measure dysfunctional HDL-C
- Principal Investigator
  
  Aoyama Takuma
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Shinshu University
Elucidation of the significance of LOX-1 and endothelial dysfunction as the pathological basis of disseminated intravascular coagulation.
- Principal Investigator
  
  Sawamura Tatsuya
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Shinshu University
Elucidation of the mechanism of cerebral infarction using genome-edited ratsPrincipal Investigator
- Principal Investigator
  
  Akemi Kakino
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Shinshu University
Elucidation of the relationships between pathogenic substances and DAMPs receptors.
- Principal Investigator
  
  Fujita Yoshiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Shinshu University
Elucidation of the anti-atherogenic mechanism of adiponectinPrincipal Investigator
- Principal Investigator
  
  Kakino Akemi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Shinshu University
Identification of an endogenous oxidized LDL blocker and elucidation of its regulatory mechanism of arteriosclerotic diseasesPrincipal Investigator
- Principal Investigator
  
  KAKINO Akemi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Shinshu University
  National Cardiovascular Center Research Institute
Elucidation of physiological significance of LOX-1 binding molecules
- Principal Investigator
  
  SAWAMURA Tatsuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Shinshu University
  National Cardiovascular Center Research Institute

All 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Patent

[Journal Article] Editorial commentary: L5: An LDL fraction in which pathogenic activity of LDL is concentrated2017
- Author(s)
  Sawamura, T., Fujita, Y., Horiuchi, S., Kakino, A.
- Journal Title
  
  Trends Cardiovasc Med
  
  Volume: 27 Issue: 4 Pages: 247-248
- DOI
  10.1016/j.tcm.2016.12.004
- Data Source
  KAKENHI-PROJECT-16K19192
[Journal Article] LOX-1 in Ischemic Stroke2017
- Author(s)
  Sawamura, T., Fujita, Y., Horiuchi, S., Kakino, A.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 6 Pages: 566-568
- DOI
  10.5551/jat.ED071
- NAID
  130005687830
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Data Source
  KAKENHI-PROJECT-16K19192
[Journal Article] Modified LDL functions in human and LOX-1-mediated signal transductions2016
- Author(s)
  Kakino, A., Sawamura, T.
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 147 Issue: 2 Pages: 107-113
- DOI
  10.1254/fpj.147.107
- NAID
  130005125650
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-25670133
[Journal Article] Developmental Endothelial Locus-1 (Del-1) Inhibits Oxidized Low-Density Lipoprotein Activity by Direct Binding, and Its Overexpression Attenuates Atherogenesis in Mice2016
- Author(s)
  Akemi Kakino, Yoshiko Fujita, Atsushi Nakano, Sayaka Horiuchi, Tatsuya Sawamura
- Journal Title
  
  Circ J
  
  Volume: 80 Issue: 12 Pages: 2541-2549
- DOI
  10.1253/circj.CJ-16-0808
- NAID
  130005284982
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-16K19192
[Journal Article] High Levels of Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Acute Stroke: An Age- and Sex-Matched Cross-Sectional Study2016
- Author(s)
  Yokota, C., Sawamura, T., Watanabe, M., Kokubo, Y., Fujita, Y., Kakino, A., Nakai, M., Toyoda, K., Miyamoto, Y. and Minematsu, K.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 23 Issue: 10 Pages: 1222-1226
- DOI
  10.5551/jat.32466
- NAID
  130005598268
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-16K19192
[Journal Article] Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin.2016
- Author(s)
  Yokoyama C, Aoyama T, Ido T, Kakino A, Shiraki T, Tanaka T, Nishigaki K, Hasegawa A, Fujita Y, Sawamura T, Minatoguchi S.
- Journal Title
  
  PLoS One
  
  Volume: 11（5） Issue: 5 Pages: e0154994-e0154994
- DOI
  10.1371/journal.pone.0154994
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461064, KAKENHI-PROJECT-16K19192
[Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.2015
- Author(s)
  Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T and Rakugi H.
- Journal Title
  
  The FASEB Journal
  
  Volume: Apr 15 Issue: 8 Pages: 3342-3356
- DOI
  10.1096/fj.15-271627
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24601021, KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25670133, KAKENHI-PROJECT-25293063
[Journal Article] 変性LDLとsLOX-1のバイオマーカーとしての意義2015
- Author(s)
  垣野明美, 沢村達也
- Journal Title
  
  動脈硬化予防
  
  Volume: 14 Pages: 40-45
- Data Source
  KAKENHI-PROJECT-25670133
[Journal Article] Lectin-like oxidized low-density lipoprotein recepto-r1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state.2015
- Author(s)
  Nakayachi M, Ito J, Hayashida C, Ohyama Y, Kakino A, Okayasu M, Sato T, Ogasawara T, Kaneda T, Suda N, Sawamura T, Hakeda Y.
- Journal Title
  
  Bone
  
  Volume: 75 Pages: 170-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670133
[Journal Article] LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men.2013
- Author(s)
  Okamura T, Sekikawa A, Sawamura T, Kadowaki T, Barinas-Mitchell E, Mackey RH, Kadota A, Evans RW, Edmundowicz D, Higashiyama A, Nakamura Y, Abbott RD, Miura K, Fujiyoshi A, Fujita Y, Murakami Y, Miyamatsu N, Kakino A, Maegawa H, Murata K,　Horie M, Mitsunami K, Kashiwagi A, Kuller LH, Ueshima H
- Journal Title
  
  Atherosclerosis
  
  Volume: 229 Issue: 1 Pages: 240-245
- DOI
  10.1016/j.atherosclerosis.2013.04.023
- NAID
  130004782561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390178, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-25893300
[Patent] 酸化ＬＤＬ阻害剤2015
- Inventor(s)
  沢村達也、垣野明美
- Industrial Property Rights Holder
  国立研究開発法人国立循環器病研究センター、国立大学法人信州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-08-15
- Acquisition Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-25293063
[Patent] 抗血液凝固剤2013
- Inventor(s)
  沢村達也、藤田佳子、垣野明美
- Industrial Property Rights Holder
  独立行政法人　国立循環器病研究センター
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-273308
- Filing Date
  2013-12-27
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] アディポネクチン系と酸化LDL系の相互拮抗作用2017
- Author(s)
  垣野明美, 藤田佳子, 堀内清香, 沢村達也
- Organizer
  第27回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-16K19192
[Presentation] アディポネクチンの抗動脈硬化作用の検討2017
- Author(s)
  垣野明美, 藤田佳子, 堀内清香, 沢村達也
- Organizer
  第64回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-16K19192
[Presentation] 受容体結合活性で測定する変性LDL2017
- Author(s)
  沢村達也, 岡村智教, 藤田佳子, 堀内清香, 垣野明美
- Organizer
  第49回日本動脈硬化学会
- Data Source
  KAKENHI-PROJECT-16K19192
[Presentation] Identification of oxLDL blocking protein and its anti-atherogenic function2016
- Author(s)
  Kakino, A., Nakano, A., Fujita, Y., Sawamura, T.
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] Adiponectin as a blocker of oxidized LDL.2016
- Author(s)
  Kakino, A., Fujita, Y., Sawamura, T.
- Organizer
  The 84th European Atherosclerosis Society Congress (EAS 2016)
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2016-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19192
[Presentation] Oxidized LDL and adiponectin interact and regulate the other’s respective functions.2016
- Author(s)
  Kakino, A., Fujita, Y., Sawamura, T.
- Organizer
  American Heart Association’s Scientific Sessions 2016
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19192
[Presentation] AT1はLOX-1を介した酸化LDLによるシグナル伝達を促進する2015
- Author(s)
  垣野明美、山本浩一、藤田佳子、楽木宏美、沢村達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  ハイアットリージェンシー京都（京都）
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] PAF receptor interacts with LOX-1 and promotes oxidized LDL-induced cellular responses2015
- Author(s)
  Kakino, A., Fujita, Y., Yamamoto, K., Rakugi, H., Sawamura, T
- Organizer
  17th International Congress on Atherosclerosis 2015
- Place of Presentation
  Amsterdam (Holland)
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] PAF receptor interacts with LOX-1 and promotes oxidized LDL-induced cellular responses2015
- Author(s)
  Kakino, A., Fujita, Y., Yamamoto, K., Rakugi, H., Sawamura, T.
- Organizer
  17th International Congress on Atherosclerosis
- Place of Presentation
  Amsterdam RAI Congress Centre (オランダ)
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] AT1はLOX-1を介した酸化LDLによるシグナル伝達を促進する2015
- Author(s)
  垣野明美、山本浩一、藤田佳子、楽木宏美、沢村達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都府京都市、ハイアットリージェンシー京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] 脳出血とアテローム血栓性脳梗塞における可溶性Lectin-like oxidized LDL receptor-1高値：症例・対照研究2015
- Author(s)
  横田千晶、沢村達也、渡邊至、小久保喜弘、藤田佳子、垣野明美、中井陸運、豊田一則、宮本恵宏、峰松一夫
- Organizer
  第27回日本脳循環代謝学会総会
- Place of Presentation
  富山県富山市、富山国際会議場
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] LOX-1 遺伝子欠損SHRSPの作製とその形質の予備的解析2014
- Author(s)
  垣野明美、李　蕾、池末昌弘、中野厚史、藤田佳子、岡澤　慎、真下知士、沢村達也
- Organizer
  第50回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  和歌山県立医科大学生涯研修センター、和歌山
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] AT1 directly interacting with LOX-1 mediates signal transduction induced by oxidized LDL.2014
- Author(s)
  A. Kakino, K.Yamamoto, A.Nakano, L.Li, Y. Fujita, H.Rakugi, T.Sawamura
- Organizer
  The 82nd Congress of the European Atherosclerosis Society (EAS 2014)
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-06-01
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Overexpression of Del-1, An oxidized LDL blocking protein, suppressed atherogenesis in mice without lowering oxidized LDL concentration, but with reducing LOX-1 ligand containing apoB activity (LAB).2014
- Author(s)
  Akemi. Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura.
- Organizer
  American Association for Clinical Chemistry Annual Meeting and Clinical Lab Expo
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] 内因性蛋白質による新しい酸化LDL作用阻害機構2013
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] Del-1は酸化LDL－受容体相互作用を阻害し、血管壁脂質沈着を抑制する Del-1 as an endogenous blocker of oxidized LDL which suppresses arterial lipid accumulation2013
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第17回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] 酸化LDL作用の新しい抑制機構2013
- Author(s)
  垣野明美
- Organizer
  第14回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] Identification of Endogenous Anti-Atherogenic Protein Which Blocks the Interaction between Oxidized LDL and Its Receptors2013
- Author(s)
  Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
- Organizer
  AHA Scientific Sessions 2013
- Place of Presentation
  アメリカ・ダラス
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] An endogenous blocker of oxidized LDL2013
- Author(s)
  Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
- Organizer
  13th International Conference on Endothelin
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] Del-1は酸化LDL－受容体相互作用を阻害し、血管壁脂質沈着を抑制する2013
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第17回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] An endogenous blocker of oxidized LDL2013
- Author(s)
  Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
- Organizer
  13th International Conference on Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] 内因性蛋白質による新しい酸化LDL作用阻害機構 Inhibition of oxidized LDL action by an endogenous protein2013
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Identification of Endogenous Anti-Atherogenic Protein Which Blocks the Interaction between Oxidized LDL and Its Receptors2013
- Author(s)
  Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
- Organizer
  AHA Scientific Sessions 2013
- Place of Presentation
  Dallas, Texas
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] 酸化LDL阻害分子Del-1の過剰発現は、マウス血管壁脂質沈着を抑制する2013
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第23回日本循環薬理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] AT1はLOX-1を介した酸化LDLによるシグナル伝達と血管壁脂質沈着を促進する2013
- Author(s)
  垣野明美、山本浩一、中野厚史、李蕾、藤田佳子、楽木宏実、沢村達也
- Organizer
  第49回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Regulation Of Cellular Lipid Metabolism In Atherogenesis2013
- Author(s)
  Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
- Organizer
  The 81st Congress of the European Atherosclerosis Society (EAS 2013)
- Place of Presentation
  フランス・リヨン
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] 酸化LDL阻害分子Del-1の過剰発現は、マウス血管壁脂質沈着を抑制する
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第23回日本循環薬理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] AT1 promotes oxLDL-induced cell responses through interact with LOX-1.
- Author(s)
  Akemi Kakino, Koichi Yamamoto, Lei Li, Yoshiko Fujita, Hiromi Rakugi, Tatsuya Sawamura
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場、神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Overexpression of Del-1, an oxLDL blocking protein, suppressed atherogenesis in mice without lowering oxLDL concentration, but with reducing LOX-1 ligand containing apoB activity (LAB)
- Author(s)
  Kakino A, Nakano A, Fujita Y, Sawamura T
- Organizer
  2014 AACC ANNUAL MEETING
- Place of Presentation
  USA, Chicago
- Year and Date
  2014-07-29 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] AT1 directly interacting with LOX-1 mediates signal transduction induced by oxidized LDL.
- Author(s)
  Kakino A, Yamamoto K, Li L, Fujita Y, Rakugi H, Sawamura T
- Organizer
  The 82nd Congress of the European Atherosclerosis Society (EAS 2014)
- Place of Presentation
  Spain, Madrid
- Year and Date
  2014-05-31 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] Interaction between AT1 and LOX-1 promote oxLDL-induced cell responses.
- Author(s)
  Kakino A, Yamamoto K, Li L, Fujita Y, Rakugi H, Sawamura T
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] AT1 promotes oxLDL-induced cell responses through interact with LOX-1.
- Author(s)
  Kakino A, Yamamoto K, Li L, Fujita Y, Rakugi H, Sawamura T
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25670133
[Presentation] Interaction between AT1 and LOX-1 promote oxLDL-induced cell responses.
- Author(s)
  Akemi Kakino, Koichi Yamamoto, Lei Li, Yoshiko Fujita, Hiromi Rakugi, Tatsuya Sawamura
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25293063

1. SAWAMURA Tatsuya (30243033)

# of Collaborated Projects: 8 results

# of Collaborated Products: 17 results
2. FUJITA Yoshiko (30416218)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. 細田洋司 (40359807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Aoyama Takuma (60422713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 堀内清香 (20789820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 川崎雅規 (50214630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 河嶋秀和 (70359438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIGASHIYAMA Aya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. MINATOGUCHI Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 岡村智教

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 上島弘嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 三浦克之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 中野厚史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 西垣和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kakino Akemi 垣野 明美

KAKINO Akemi 垣野 明美

Research Projects

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高尿酸血症から痛風発作に至る生体分子機構の研究

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骨格筋の新機能としての老廃物除去機能を解明する

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血管機能異常による高脂肪食依存性機構の解明

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Elucidation of the significance of endothelial function molecule in the pathophysiology of pulmonary arterial hypertensionPrincipal Investigator

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The risk assessment of coronary artery diseas by a novel method to measure dysfunctional HDL-C

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Elucidation of the significance of LOX-1 and endothelial dysfunction as the pathological basis of disseminated intravascular coagulation.

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Elucidation of the mechanism of cerebral infarction using genome-edited ratsPrincipal Investigator

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Elucidation of the relationships between pathogenic substances and DAMPs receptors.

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Elucidation of the anti-atherogenic mechanism of adiponectinPrincipal Investigator

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Identification of an endogenous oxidized LDL blocker and elucidation of its regulatory mechanism of arteriosclerotic diseasesPrincipal Investigator

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Elucidation of physiological significance of LOX-1 binding molecules

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[Journal Article] Editorial commentary: L5: An LDL fraction in which pathogenic activity of LDL is concentrated2017

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[Journal Article] LOX-1 in Ischemic Stroke2017

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Kakino Akemi 垣野明美

KAKINO Akemi 垣野明美