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SAWAMURA TATSUYA  沢村 達也

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SAWAMURA Tatsuya  沢村 達也

沢村 逹也  サワムラ タツヤ

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Researcher Number 30243033
Other IDs
Affiliation (Current) 2022: 信州大学, 学術研究院医学系, 教授
Affiliation (based on the past Project Information) *help 2014 – 2022: 信州大学, 学術研究院医学系, 教授
2014 – 2016: 信州大学, 医学部, 教授
2014: 国立循環器病研究センター, 血管生理部, 部長
2013: 独立行政法人国立循環器病研究センター, その他部局等, 部長
2012 – 2013: 独立行政法人国立循環器病研究センター, 研究所, 部長 … More
2012: 国立循環器病センター(研究所), 脈管整理部, 部長
2010 – 2011: 独立行政法人国立循環器病研究センター, 血管生理学部, 部長
2007: National Cardiovascular Center Research Institute, 脈管生理部, 部長
2005 – 2007: National Cardiovascular Center Research Institute, Department of Vascular Physiology, Director, 脈管生理部, 部長
2004: 国立循環器病センター研究所, 脈管生理部, 部長
1997 – 2002: 国立循環器病センター研究所, バイオサイエンス部, 室長
2001: 国立循環器病センター 研究所, バイオサイエンス部, 室長
1995 – 1996: 京都大学, 医学研究科, 助手
1993 – 1994: 京都大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General pharmacology / General pharmacology / Biological Sciences / Basic Section 47040:Pharmacology-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
Except Principal Investigator
General pharmacology / Biological Sciences / Epidemiology and preventive medicine / Morphological basic dentistry / Basic Section 52010:General internal medicine-related … More / General medical chemistry / Thoracic surgery / Orthopaedic surgery / Cerebral neurosurgery / General internal medicine(including psychosomatic medicine) / General pharmacology / Cardiovascular medicine / Basic Section 53010:Gastroenterology-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 48030:Pharmacology-related / Basic Section 53020:Cardiology-related Less
Keywords
Principal Investigator
LOX-1 / 酸化LDL / 動脈硬化 / 酸化LDL受容体 / 血小板 / 内皮細胞 / 血管内皮細胞 / レクチン様酸化LDL受容体 / 炎症 / oxidized LDL … More / endothelial cells / エンドセリン変換酵素 / LOX-1リガンド / 受容体 / 血栓 / oxidized LDL receptor / 内膜増殖 / エンドセリンン / エンドセリン / 金属プロテアーゼ / 高脂血症 / マラリア / 酸化ストレス / 抗原提示 / 痛風 / 尿酸結晶 / 炎症・免疫 / 酸化 / LDL / GPCR / クロストーク / 変性LDL受容体 / 複合体形成 / 循環器・高血圧 / トランスジェニックマウス / ノックアウトマウス / transgenic mouse / arteriosclerosis / intimal thickening / atherosclerosis / thrombosis / intimal hyperplasia / DIC / 凝固因子 / 摂食 / 高脂肪食 / 依存性 … More
Except Principal Investigator
エンドセリン / エンドセリン受容体 / エンドセリン変換酵素 / LOX-1 / 一酸化窒素 / エンドセリン受容体拮抗薬 / 国際薬理学連合受容体委員会 / 国際エンドセリン会議 / endothelin / endothelin receptor / 非選択的カチオンチャネル / 脂質 / 生活習慣 / 炎症性骨破壊 / 破骨細胞 / 細胞融合 / アルツハイマー病 / アンジオテンシンII受容体 / AGE受容体 / レニン-アンジオテンシン系 / 認知症 / 高血圧 / endothelin converting enzyme / 酸化LDL / sLOX-1 / HDLコレステロール / LDLコレステロール / 疫学研究 / カルシウムチャネル / G蛋白質 / カルシウム / カルシウムインフラックス / メフェナム酸 / カルシウム拮抗薬 / テトラヒドロビオプテリン / ドーパミン遊離 / 細胞内遊離カルシウム濃度 / パッチクランプ / カルシウムチャンネル / 結合実験 / 金属プロテアーゼ / 内皮細胞 / ビッグエンドセリン / ビオプテリン / 結合蛋白質 / 一酸化窒素合成酵素 / クローニング / 感染 / ノックアウトマウス / トリパノソーマ / バベシア / トキソプラズマ / 心臓移植 / レクチン様酸化LDL受容体 / 慢性拒絶反応 / 医療・福祉 / 細胞・組織 / トランスレーショナルリサーチ / 老化 / 細胞・細胞 / トランスレーショナルリサ / ApoB含有LOX-1リガンド / 血中可溶型LOX-1 / 疫学調査 / carotid IMT / CAVI / 動脈硬化 / 血中可溶型LOX-1 / ApoB含有LOX-1リガンド / 頸動脈内膜中膜複合体 / CAVI / 腎機能 / 終末糖化産物受容体関連物質 / ペントシジン / 吹田コホート / 急性脳卒中 / 急性期脳卒中 / カットオフ値 / バイオマーカー / sRAGE / esRAGE / ケース・コントロール研究 / 骨芽細胞 / 破骨細胞形成 / 炎症性骨吸収 / RANKL産生 / 降圧薬 / レニンーアンジオテンシン系 / AAAAA / 老年病 / 薬物受容体 / 受容体拮抗薬 / international receptor committee / conference on endothelin / endothelin antagonist / 血管内皮 / 血管収縮 / 細胞増殖 / ジストログリカン / 変性LDL受容体 / アルギニン輸送体 / 受容体輸送活性相関 / 変成LDL受容体 / 電位依存性カルシウムチャネル / 非選択的陽イオンチャネル / カチオンチャネル / vascular endothelium / nitric oxide / oxidized LDL / vasoconstriction / cell growth, dystroglycan / endothelin receptor antagonist / Receptor Nomenclature and Drug Classification Committee / International Union of Pharmacological Sciences / International Conference on Endothelin / エンドセリ / Endothelin / Endothelin receptor / IUPHA / Endothelium / Endothelin antagonist / DAMPs / 受容体 / 心血管 / 血液 / LDL受容体 / 細胞膜外葉 / phosphatidylethanolamine / ABCG1 / 炎症整骨破壊 / 拡張型心筋症 / 心不全 / 酸化・変性脂質 / LDLコレステロール / HDLコレステロール / sLOX-1 / sLOX-1 / 変性HDL-C / 冠動脈硬化症 / C型慢性肝炎 / 直接作用型抗ウイルス剤 / プロ蛋白転換酵素サブチリシン/ケキシン9型 / 脂質の量的変動 / 脂質の質的変動 / 脂質変動 / 脂質プロファイル / ウイルス学的著効 / PCSK9 / 脂質異常症 / 生活習慣病 / ワクチン / アミロイドβ / アンジオテンシン / 変性リポ蛋白 / 肺高血圧症 / ゲノム編集ラット / アンジオテンシンII Less
  • Research Projects

    (40 results)
  • Research Products

    (177 results)
  • Co-Researchers

    (83 People)
  •  脂質異常症が高血圧や高血圧性腎障害を増強する新規メカニズムの解明

    • Principal Investigator
      野里 陽一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University
  •  血管機能異常による高脂肪食依存性機構の解明Principal Investigator

    • Principal Investigator
      沢村 達也
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Shinshu University
  •  変性リポ蛋白を含む脂質プロフィールと脳・心血管疾患の関連、その規定要因の解明

    • Principal Investigator
      岡村 智教
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Keio University
  •  肺高血圧症病態生理における血管内皮機能分子の意義の解明

    • Principal Investigator
      垣野 明美
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Shinshu University
  •  The risk assessment of coronary artery diseas by a novel method to measure dysfunctional HDL-C

    • Principal Investigator
      青山 琢磨
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Shinshu University
  •  Elucidation of the significance of LOX-1 and endothelial dysfunction as the pathological basis of disseminated intravascular coagulation.Principal Investigator

    • Principal Investigator
      Sawamura Tatsuya
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Shinshu University
  •  Interactions between lipid profile and PCSK9 changes and a role of oxidatively modified LDL on DAAs treatment

    • Principal Investigator
      Joshita Satoru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Shinshu University
  •  Basic research for a new concurrent treatment against lifestyle diseases and Alzehimer disease.

    • Principal Investigator
      Yamamoto Koichi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Elucidation of the relationships between pathogenic substances and DAMPs receptors.

    • Principal Investigator
      Fujita Yoshiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Shinshu University
  •  Elucidation of the mechanism of gout attacksPrincipal Investigator

    • Principal Investigator
      Sawamura Tatsuya
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Shinshu University
  •  Elucidation of Involvement of LOX-1 in inflammatory bone destruction and the molecular mechanism for the LOX-1 actions, and an approach to develop the new drug for bone diseases.

    • Principal Investigator
      HAKEDA Yoshiyuki
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Meikai University
  •  Assessment of quality of lipid parameters as a novel risk factor for cardiovascular diseases in community-based epidemiologic studies.

    • Principal Investigator
      OKAMURA Tomonori
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Epidemiology and preventive medicine
    • Research Institution
      Keio University
  •  Basic research for the clinical application of drugs for a life style disease to treat Alzheimer's disease.

    • Principal Investigator
      Yamamoto Koichi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Severity assessment and prognostic evaluation of idiopathic dilated cardiomyopathy by measurement of soluble LOX-1

    • Principal Investigator
      AOYAMA Takuma
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Gifu University
  •  Elucidation of physiological significance of LOX-1 binding moleculesPrincipal Investigator

    • Principal Investigator
      SAWAMURA Tatsuya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Shinshu University
      National Cardiovascular Center Research Institute
  •  The elucidation of the role of lipid in bone resorption of inflammatory bone diseases; in particular, the exploration of the role of LOX-1 as an oxidized LDL receptor

    • Principal Investigator
      HAKEDA Yoshiyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Meikai University
  •  The effect of soluble form LOX-1 and LOX-1 ligands containing apolipoprotein B on subclinical atherosclerosis in community dwellers..

    • Principal Investigator
      OKAMURA Tomonori
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Epidemiology and preventive medicine
    • Research Institution
      Keio University
  •  Clinical implication of biomarker for patients with acute stroke

    • Principal Investigator
      YOKOTA Chiaki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Pathophysiological significance of the factor which enhances the action of oxidized LDL, platelets, and leukocytes on vascular wall.Principal Investigator

    • Principal Investigator
      SAWAMURA Tatsuya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Involvement of the oxidized low-density lipoprotein/lectin-like oxidized low-density lipoprotein receptor-1 system to joint cartilage degeneration

    • Principal Investigator
      AKAGI Masao
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kinki University
  •  Clarification of the mechanisms of cardiovascular dysfunction and the resultant organ failurePrincipal Investigator

    • Principal Investigator
      SAWAMURA Tatsuya
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  酸化LDL及びレクチン様酸化LDL受容体(LOX-1)の心移植後慢性拒絶への関与

    • Principal Investigator
      菅 理晴
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Thoracic surgery
    • Research Institution
      National Cardiovascular Center Research Institute
  •  STUDY ON THE SIGNIFICANCE OF LOX-1 IN OXIDATIVE STRESS-RELATED BIOLOGICAL RESPONSESPrincipal Investigator

    • Principal Investigator
      SAWAMURA Tatsuya
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  原虫感染におけるスカベンジャー受容体の機能

    • Principal Investigator
      鈴木 宏志
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Obihiro University of Agriculture and Veterinary Medicine
  •  熱帯熱マラリアの病理における血管内皮細胞の酸化LDL受容体LOX-1の役割Principal Investigator

    • Principal Investigator
      沢村 達也
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      National Cardiovascular Center Research Institute
  •  レクチン様酸化LDL受容体の機能と病態生理への関わりPrincipal Investigator

    • Principal Investigator
      沢村 達也
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  レクチン様酸化LDL受容体の機能と病態生理的役割Principal Investigator

    • Principal Investigator
      沢村 達也
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Cardiovascular Center Research Institute
  •  レクチン様酸化LDL受容体の機能と病態生理的役割Principal Investigator

    • Principal Investigator
      沢村 達也
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Cardiovascular Center Research Institute
  •  血管内皮細胞の機能変化のメカニズムPrincipal Investigator

    • Principal Investigator
      沢村 達也
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General pharmacology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Investigations for developing novel diagnostic methods, therapeutics, and drugs utilizing lectin-like oxidized LDL receptor-1 (LOX-1)Principal Investigator

    • Principal Investigator
      SAWAMURA Tatsuya
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Pharmacology

    • Principal Investigator
      MASAKI Tomoh
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      General pharmacology
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Pharmacology of endothelin and endothelin receptor

    • Principal Investigator
      MASAKI Tomoh
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY
  •  Study on the regulatory mechanisms of endothelium-dependent vasoconstriction and growth of vascular cells

    • Principal Investigator
      MASAKI Tomoh
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      National Cardiovascular Center Research Institute
      Kyoto University
  •  新しい循環調節薬としてのエンドセリン変換酵素抑制薬開発のための研究

    • Principal Investigator
      真崎 知生, 眞崎 知生
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University
  •  バイオプテリン結合活性をもつ新しい機能蛋白質群のcDNAクローニング

    • Principal Investigator
      三輪 聡一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University
  •  エンドセリン変換酵素によるエンドセリン産生制御Principal Investigator

    • Principal Investigator
      沢村 達也
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University
  •  Pharmacology of endothelin receptor and its agonist/antagonist

    • Principal Investigator
      MISAKI Tomoh, 真崎 知生
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY
  •  エンドセリン誘発収縮に関与する新しい因子の検索とそのクローニング

    • Principal Investigator
      真崎 知生, MISAKI Tomoh
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  テトラヒドロビオプテリン受容体のクローニング及びその機能解析

    • Principal Investigator
      三輪 聡一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University
  •  エンドセリン変換酵素によるエンドセリン産生制御Principal Investigator

    • Principal Investigator
      沢村 逹也
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Patent

  • [Journal Article] RAGE ligands stimulate angiotensin II type I receptor (AT1) via RAGE/AT1 complex on the cell membrane2021

    • Author(s)
      Yokoyama Serina、Kawai Tatsuo、Yamamoto Koichi、Yibin Huang、Yamamoto Hiroko、Kakino Akemi、Takeshita Hikari、Nozato Yoichi、Fujimoto Taku、Hongyo Kazuhiro、Takahashi Toshimasa、Nakagami Futoshi、Akasaka Hiroshi、Takami Yoichi、Takeya Yasushi、Sugimoto Ken、Sawamura Tatsuya、Rakugi Hiromi
    • Journal Title

      Scientific Reports

      Volume: 11 Pages: 5759-5759

    • DOI

      10.1038/s41598-021-85312-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02732
  • [Journal Article] The relationship between serum levels of LOX-1 ligand containing ApoAI as a novel marker of dysfunctional HDL and coronary artery calcification in middle-aged Japanese men2020

    • Author(s)
      Hirata A, Kakino A, Okamura T, Usami Y, Fujita Y, Kadota A, Fujiyoshi A, Hisamatsu T, Kondo K, Segawa H, Sawamura T, Miura K, Ueshima H; SESSA Research Group.
    • Journal Title

      Atherosclerosis

      Volume: 313 Pages: 20-25

    • DOI

      10.1016/j.atherosclerosis.2020.09.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05249, KAKENHI-PROJECT-18H04074
  • [Journal Article] LDL uptake-dependent phosphatidylethanolamine translocation to the cell surface promotes fusion of osteoclast-like cells.2020

    • Author(s)
      Kitano J F V, Ohyama Y, Hayashida C, Ito J, Okayasu M, Sato T, Ogasawara T, Tsujita M, Kakino A, Shimada J, Sawamura T, and Hakeda Y.
    • Journal Title

      Journal of Cell Science

      Volume: ー

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05505
  • [Journal Article] A novel cell-free, non-fluorescent method to measure LOX-1-binding activity corresponding to the functional activity of HDL.2019

    • Author(s)
      Kakino A, Usami Y, Horiuchi S, Fujita Y, Kotani K, Chen CH, Okamura T, Sawamura T.
    • Journal Title

      J Atheroscler Thromb

      Volume: in press Issue: 11 Pages: 947-958

    • DOI

      10.5551/jat.47183

    • NAID

      130007740412

    • ISSN
      1340-3478, 1880-3873
    • Description
      in press
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05249, KAKENHI-PROJECT-18H00461
  • [Journal Article] High Levels of Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Acute Stroke: An Age- and Sex-Matched Cross-Sectional Study2016

    • Author(s)
      Yokota, C., Sawamura, T., Watanabe, M., Kokubo, Y., Fujita, Y., Kakino, A., Nakai, M., Toyoda, K., Miyamoto, Y. and Minematsu, K.
    • Journal Title

      J Atheroscler Thromb

      Volume: 印刷中 Issue: 10 Pages: 1222-1226

    • DOI

      10.5551/jat.32466

    • NAID

      130005598268

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Lectin-like oxidized low density lipoprotein receptor 1-deficient mice show resistance to instability-induced osteoarthritis.2016

    • Author(s)
      K Hashimoto, S Mori, Y Oda, A Nakano, T Sawamura & M Akagi
    • Journal Title

      Scand J Rheumatol

      Volume: 2 Pages: 1-11

    • DOI

      10.3109/03009742.2015.1135979

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-16K10923
  • [Journal Article] Electronegative low-density lipoprotein increases coronary artery disease risk in uremia patients on maintenance hemodialysis.2016

    • Author(s)
      Chang, C.T., Wang, G.J., Kuo, C.C., Hsieh, J.Y., Lee, A.S., Chang, C.M., Wang, C.C., Shen, M.Y., Huang, C.C., Sawamura, T., Yang, C.Y., Stancel, N. and Chen, C.H.
    • Journal Title

      Medicine (Baltimore)

      Volume: 95

    • DOI

      10.1097/md.0000000000002265

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin.2016

    • Author(s)
      Yokoyama C, Aoyama T, Ido T, Kakino A, Shiraki T, Tanaka T, Nishigaki K, Hasegawa A, Fujita Y, Sawamura T, Minatoguchi S.
    • Journal Title

      PLoS One

      Volume: 11(5)

    • DOI

      10.1371/journal.pone.0154994

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461064
  • [Journal Article] Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation.2016

    • Author(s)
      Shen, M.Y., Chen, F.Y., Hsu, J.F., Fu, R.H., Chang, C.M., Chang, C.T., Liu, C.H., Wu, J.R., Lee, A.S., Chan, H.C., Sheu, J.R., Lin, S.Z., Shyu, W.C., Sawamura, T., Chang, K.C., Hsu, C.Y. and Chen, C.H.
    • Journal Title

      Blood

      Volume: 127 Pages: 1336-1345

    • DOI

      10.1182/blood-2015-05-646117

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Serum level of LOX-1 ligand containing ApoB is associated with increased carotid intima-media thickness in Japanese community-dwelling men, especially those with hypercholesterolemiaLOX-1 ligand and IMT in Japanese.2016

    • Author(s)
      Okamura T, Miura K, Sawamura T, Kadota A, Hisamatsu T, Fujiyoshi A, Miyamatsu N, Takashima N, Miyagawa N, Kadowaki T, Ohkubo T, Murakami Y, Nakamura Y, Ueshima H.
    • Journal Title

      J Clin Lipidol

      Volume: 10 Pages: 172-180

    • DOI

      10.1016/j.jacl.2015.10.010

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253046, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-26293140, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-15K10330
  • [Journal Article] The relationship between lectin-like oxidized low-density lipoprotein receptor-1 ligands containing apolipoprotein B and cardio-ankle vascular index in healthy community inhabitants: The KOBE study.2015

    • Author(s)
      Sugiyama D, Higashiyama A, Wakabayashi I, Kubota Y, Adachi Y, Hayashibe A, Kawamura K, Kuwabara K, Nishimura K, Kadota A, Nishida Y, Hirata T, Imano H, Miyamatsu N, Miyamoto Y , Sawamura T, Okamura T.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 22

    • NAID

      130004704373

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23390178
  • [Journal Article] Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction.2015

    • Author(s)
      Chang, K.C., Lee, A.S., Chen, W.Y., Lin, Y.N., Hsu, J.F., Chan, H.C., Chang, C.M., Chang, S.S., Pan, C.C., Sawamura, T., Chang, C.T., Su, M.J. and Chen, C.H
    • Journal Title

      J Mol Cell Cardiol

      Volume: 84 Pages: 36-44

    • DOI

      10.1016/j.yjmcc.2015.03.016

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor2015

    • Author(s)
      Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T and Rakugi H.
    • Journal Title

      THE FASEB JOURNAL

      Volume: Apr 15 Pages: 3342-3356

    • DOI

      10.1096/fj.15-271627

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24601021, KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25670133, KAKENHI-PROJECT-25293063
  • [Journal Article] Human serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor2015

    • Author(s)
      Tomita T, Ieguchi K, Sawamura T, Maru Y
    • Journal Title

      PLOS ONE

      Volume: 10(3)

    • DOI

      10.1371/journal.pone.0118835

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25122716, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-25870760, KAKENHI-PROJECT-26440063
  • [Journal Article] The Relationship between Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Ligands Containing Apolipoprotein B and the Cardio-Ankle Vascular Index in Healthy Community Inhabitants: The KOBE Study2015

    • Author(s)
      Sugiyama D, Higashiyama A, Wakabayashi I, Kubota Y, Adachi Y, Hayashibe A, Kawamura K, Kuwabara K, Nishimura K, Kadota A, Nishida Y, Hirata T, Imano H, Miyamatsu N, Miyamoto Y, Sawamura T, Okamura T.
    • Journal Title

      J Atheroscler Thromb

      Volume: 未定 Issue: 5 Pages: 499-508

    • DOI

      10.5551/jat.26450

    • NAID

      130004704373

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590844, KAKENHI-PROJECT-25293063
  • [Journal Article] Cross-talk between LOX-1 and PCSK9 in vascular tissues.2015

    • Author(s)
      Ding, Z., Liu, S., Wang, X., Deng, X., Fan, Y., Shahanawaz, J., Shmookler Reis, R.J., Varughese, K.I., Sawamura, T. and Mehta, J.L.
    • Journal Title

      Cardiovasc Res

      Volume: 107 Pages: 556-567

    • DOI

      10.1093/cvr/cvv178

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] The biphasic effects of oxidized-low density lipoprotein on the vasculogenic function of endothelial progenitor cells.2015

    • Author(s)
      Lin, F.Y., Tsao, N.W., Shih, C.M., Lin, Y.W., Yeh, J.S., Chen, J.W., Nakagami, H., Morishita, R., Sawamura, T. and Huang, C.Y.
    • Journal Title

      PLoS One

      Volume: 10

    • DOI

      10.1371/journal.pone.0123971

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Effect of sodium tanshinone IIA sulfonate treatment in a rat model of preeclampsia.2015

    • Author(s)
      Morton, J. S. Quon, A. Cheung, P. Y. Sawamura, T. Davidge, S. T.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 308

    • DOI

      10.1152/ajpregu.00222.2014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state2015

    • Author(s)
      Nakayachi M, Ito J, Hayashida C, Ohyama Y, Kakino A, Okayasu M, Sato T, Ogasawara T, Kaneda T, Suda N, Sawamura T, Hakeda Y
    • Journal Title

      BONE

      Volume: 75 Pages: 170-182

    • DOI

      10.1016/j.bone.2015.02.025

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659916, KAKENHI-PROJECT-25293422, KAKENHI-PROJECT-26870540, KAKENHI-PROJECT-26463085, KAKENHI-PROJECT-15K15759, KAKENHI-PROJECT-26670895, KAKENHI-PROJECT-25293376
  • [Journal Article] LOX-1 in atherosclerotic disease.2015

    • Author(s)
      Sawamura, T. Wakabayashi, I. Okamura, T.
    • Journal Title

      Clin Chim Acta

      Volume: 440 Pages: 157-163

    • DOI

      10.1016/j.cca.2014.11.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Pitavastatin decreases serum LOX-1 ligand levels and MT1-MMP expression in CD14-positive mononuclear cells in hypercholesterolemic patients.2014

    • Author(s)
      Uzui, H., Hayashi, H., Nakae, I., Matsumoto, T., Uenishi, H., Hayasaki, H., Asaji, T., Matsui, S., Miwa, K., Lee, J.D., Tada, H., Sawamura, T. and Fujita, M.
    • Journal Title

      Int J Cardiol

      Volume: 176 Pages: 1230-1232

    • DOI

      10.1016/j.ijcard.2014.07.213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Prevention of export of anoxia/reoxygenation injury from ischemic to nonischemic cardiomyocytes via inhibition of endocytosis.2014

    • Author(s)
      Khaidakov, M., Mercanti, F., Wang, X., Ding, Z., Dai, Y., Romeo, F., Sawamura, T. and Mehta, J.L.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 306

    • DOI

      10.1152/ajpheart.00043.2014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] 変性LDL(アポBを含むLOX-1リガンド)と頸動脈内膜中膜複合体の関連:日本と米国白人の中年男性における検討.シリーズ:日本発臨床研究の紹介と反省点を語る2014

    • Author(s)
      岡村智教、関川 暁、沢村達也、 上島弘嗣
    • Journal Title

      日本内科学会雑誌

      Volume: 103 Pages: 173-180

    • Data Source
      KAKENHI-PROJECT-23390178
  • [Journal Article] Significance of soluble lectin-like oxidized LDL receptor-1 levels in systemic and coronary circulation in acute coronary syndrome.2014

    • Author(s)
      Misaka T, Suzuki S, Sakamoto N, Yamaki T, Sugimoto K, Kunii H, Nakazato K, Saitoh S, Sawamura T, Ishibashi T, Takeishi Y
    • Journal Title

      Biomed Res Int, 2014

      Volume: 2014 Pages: 649185-649185

    • DOI

      10.1155/2014/649185

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591064, KAKENHI-PROJECT-24591100, KAKENHI-PROJECT-25293063
  • [Journal Article] LOX-1 plays an important role in ischemia-induced angiogenesis of limbs.2014

    • Author(s)
      Shiraki, T., Aoyama, T., Yokoyama, C., Hayakawa, Y., Tanaka, T., Nishigaki, K., Sawamura, T. and Minatoguchi, S.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0114542

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Lectin-like oxidized low-density lipoprotein 1(LOX-1) receptor inhibition protects against pre-elamspsia plasma mediated vascular dysfunction2013

    • Author(s)
      English, F.A., McCarthy, F.P., McSweeney, C.L., Quon, A.L., Morton, J.S., Sawamura, T.
    • Journal Title

      American Journal of Hypertension

      Volume: 26 Pages: 279-286

    • DOI

      10.1093/ajh/hps035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051, KAKENHI-PROJECT-25293063
  • [Journal Article] Oxidized Low Density Lipoprotein (LDL) Affects Hyaluronan Synthesis in Human Aortic Smooth Muscle Cells.2013

    • Author(s)
      181. Viola, M., Bartolini, B., Vigetti, D., Karousou, E., Moretto, P., Deleonibus, S., Sawamura, T., Wight, T.N., Hascall, V.C., De Luca, G. and Passi, A.
    • Journal Title

      The Journal of biological chemistry

      Volume: 288 Pages: 29595-29603

    • DOI

      10.1074/jbc.m113.508341

    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Electronegative low-density lipoprotein increases C-reactive protein expression in vascular endothelial cells through the LOX-1 receptor.2013

    • Author(s)
      177. Chu, C.S., Wang, Y.C., Lu, L.S., Walton, B., Yilmaz, H.R., Huang, R.Y., Sawamura, T., Dixon, R.A., Lai, W.T., Chen, C.H. and Lu, J.
    • Journal Title

      PLoS One

      Volume: 8

    • DOI

      10.1371/journal.pone.0070533

    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men2013

    • Author(s)
      Okamura T, Sekikawa A, Sawamura T, Kadowaki T, Barinas-Mitchell E, Mackey RH, Kadota A, Evans RW, Edmundowicz D, Higashiyama A, Nakamura Y, Abbott RD, Miura K, Fujiyoshi A, Fujita Y, Murakami Y, Miyamatsu N, Kakino A, Maegawa H, Murata K, Horie M, Mitsunami K, Kashiwagi A, Kuller LH, Ueshima H
    • Journal Title

      Atherosclerosis

      Volume: 229 Pages: 240-245

    • DOI

      10.1016/j.atherosclerosis.2013.04.023

    • NAID

      130004782561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390178, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-25893300
  • [Journal Article] Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Plays an Important Role in Vascular Inflammation in Current Smokers2013

    • Author(s)
      180. Takanabe-Mori, R., Ono, K., Wada, H., Takaya, T., Ura, S., Yamakage, H., Satoh-Asahara, N., Shimatsu, A., Takahashi, Y., Fujita, M., Fujita, Y., Sawamura, T. and Hasegawa, K.
    • Journal Title

      J Atheroscler Thromb

      Volume: 20 Issue: 6 Pages: 585-590

    • DOI

      10.5551/jat.16436

    • NAID

      130004845439

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-25893300
  • [Journal Article] Highly electronegative LDL from patients with ST-elevation myocardial infarction triggers platelet activation and aggregation.2013

    • Author(s)
      176. Chan, H.C., Ke, L.Y., Chu, C.S., Lee, A.S., Shen, M.Y., Cruz, M.A., Hsu, J.F., Cheng, K.H., Chan, H.C., Lu, J., Lai, W.T., Sawamura, T., Sheu, S.H., Yen, J.H. and Chen, C.H.
    • Journal Title

      Blood

      Volume: 122 Pages: 3632-3641

    • DOI

      10.1182/blood-2013-05-504639

    • Data Source
      KAKENHI-PROJECT-25293063
  • [Journal Article] Small Dense Low-Density Lipoproteins Cholesterol can Predict Incident Cardiovascular Disease in an Urban Japanese Cohort: The Suita Study2013

    • Author(s)
      Arai, H., Kokubo, Y., Watanabe, M., Sawamura, T., Ito, Y., Minagawa, A., Okamura, T. and Miyamato, Y.
    • Journal Title

      J Atheroscler Thromb

      Volume: 20 Issue: 2 Pages: 195-203

    • DOI

      10.5551/jat.14936

    • NAID

      130004845433

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051, KAKENHI-PROJECT-24390174, KAKENHI-PROJECT-25293063
  • [Journal Article] Dietary Cholesterol Oxidation Products Accelerate Plaque Destabilization and Rupture Associated with Monocyte Infiltration/Activation via the MCP-1-CCR2 Pathway in Mouse Brachiocephalic Arteries: Therapeutic Effects of Ezetimibe2012

    • Author(s)
      Sato, K., Nakano, K., Katsuki, S., Matoba, T., Osada, K., Sawamura, T., Sunagawa, K. and Egashira, K.
    • Journal Title

      J Atheroscler Thromb

      Volume: 19 Issue: 11 Pages: 986-998

    • DOI

      10.5551/jat.13391

    • NAID

      130004444555

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] LOX-1: a multiligand receptor at the crossroads of response to danger signals2012

    • Author(s)
      Sawamura, T.
    • Journal Title

      Curr Opin Lipidol

      Volume: 23 Pages: 439-445

    • DOI

      10.1097/mol.0b013e32835688e4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Lectin-like oxidized low-density lipoprotein 1 receptor in a reduced uteroplacental perfusion pressure rat model of preeclampsia2012

    • Author(s)
      Morton, J.S., Abdalvand, A., Jiang, Y., Sawamura, T., Uwiera, R.R. and Davidge, S.T.
    • Journal Title

      Hypertension

      Volume: 59 Pages: 1014-1020

    • DOI

      10.1161/hypertensionaha.112.191825

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Lectin-like oxidized low-density lipoprotein receptor 1 signal is a potent biomarker and therapeutic target for human rheumatoid arthritis2012

    • Author(s)
      Ishikawa, M., Ito, H., Akiyoshi, M., Kume, N., Yoshitomi, H., Mitsuoka, H., Tanida, S., Murata, K., Shibuya, H., Kasahara, T., Kakino, A., Fujita, Y., Sawamura, T., Yasuda, T. and Nakamura, T.
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 1024-1034

    • DOI

      10.1002/art.33452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051, KAKENHI-PROJECT-23659719
  • [Journal Article] An alternative protein standard to measure activity of LOX-1 ligand containing apoB (LAB)-utilization of anti-LOX-1 single-chain antibody fused to apoB fragment2011

    • Author(s)
      Iwamoto, S., Fujita, Y., Kakino, A., Yanagida, K., Matsuda, H., Yoshimoto, R., Sawamura, T.
    • Journal Title

      J Atheroscler Thromb

      Volume: 18 Pages: 818-828

    • NAID

      130004845394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Association of atherosclerotic risk factors with oxidized low-density lipoprotein evaluated by LOX-1 ligand activity in healthy men2011

    • Author(s)
      Uchida, K., Suehiro, A., Nakanishi, M., Sawamura, T. and Wakabayashi, I.
    • Journal Title

      Clinica Chimia Acta

      Volume: 412 Pages: 1643-1647

    • DOI

      10.1016/j.cca.2011.05.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Procyanidins are potent inhibitors of LOX-1: a new player in the French Paradox2011

    • Author(s)
      Nishizuka, T., Fujita, Y., Sato, Y., Nakano, A., Kakino, A., Ohshima, S., Kanda, T., Yoshimoto, R. and Sawamura, T.
    • Journal Title

      Proc. Jpn. Acad., Ser. B

      Volume: 87 Issue: 3 Pages: 104-113

    • DOI

      10.2183/pjab.87.104

    • NAID

      130000669114

    • ISSN
      0386-2208, 1349-2896
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] An Alternative Protein Standard to Measure Activity of LOX-1 Ligand Containing apoB (LAB) - Utilization of Anti-LOX-1 Single- Chain Antibody Fused to apoB Fragment2011

    • Author(s)
      Iwamoto, S., Fujita, Y., Kakino, A., Yanagida, K., Matsuda, H., Yoshimoto, R. and Sawamura, T.
    • Journal Title

      J Atheroscler Thromb

      Volume: 18 Issue: 9 Pages: 818-828

    • DOI

      10.5551/jat.9142

    • NAID

      130004845394

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Lectin-like oxidized LDL receptor 1 is involved in CRP-mediated complement activation2011

    • Author(s)
      Fujita, Y., Yamaguchi, S., Kakino, A., Iwamoto, S., Yoshimoto, R. and Sawamura, T.
    • Journal Title

      Clin Chem

      Volume: 57 Pages: 1398-1405

    • DOI

      10.1373/clinchem.2011.168625

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] LOX-1 deletion improves neutrophil responses, enhances bacterial clearance and reduces lung injury in a murine polymicrobial sepsis model2011

    • Author(s)
      Wu, Z., Sawamura, T., Kurdowska, A.K., Ji, H.L., Idell, S. and Fu, J.
    • Journal Title

      Infect Immun

      Volume: 79 Pages: 2865-2870

    • DOI

      10.1128/iai.01317-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Lectin-like oxidized low-density lipoprotein receptor-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice.2010

    • Author(s)
      Takanabe-Mori, R., Ono, K., Sowa, N., Wada, H., Takaya, T., Horie, T., Satoh-Asahara, N., Shimatsu, A., Fujita, M., Sawamura, T., Hasegawa, K.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 398 Pages: 576-580

    • NAID

      120002511316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] High efficiency CD91- and LOX-1-mediated re-presentation of gp96-chaperoned peptides by MHC II molecules.2010

    • Author(s)
      Matsutake, T., Sawamura, T., Srivastava, P.K.
    • Journal Title

      Cancer Immun

      Volume: 10 Pages: 7-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Induction of hypertrophic chondrocyte-like phenotypes by oxidized LDL in cultured bovine articular chondrocytes through increase in oxidative stress.2010

    • Author(s)
      Kishimoto, H., Akagi, M., Zushi, S., Teramura, T., Onodera, Y., Sawamura, T., Hamanishi, C.
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 18 Pages: 1284-1290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] LOX index, a novel predictive biochemical marker for coronary heart disease and stroke.2010

    • Author(s)
      Inoue, N., Okamura, T., Kokubo, Y., Fujita, Y., Sato, Y., Nakanishi, M., Yanagida, K., Kakino, A., Iwamoto, S., Watanabe, M., Ogura, S., Otsui, K., Matsuda, H., Uchida, K., Yoshimoto, R. and Sawamura, T.
    • Journal Title

      Clin Chem

      Volume: 56 Pages: 550-558

    • DOI

      10.1373/clinchem.2009.140707

    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Aldosterone augments LOX-1-mediated low-density lipoprotein uptake in human umbilical artery endothelial cells.2010

    • Author(s)
      Taye, A., Sawamura, T., Morawietz, H.
    • Journal Title

      Pharmacol Rep

      Volume: 62 Pages: 311-318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Pitavastatin reduces lectin-like oxidized low-density lipoprotein receptor-1 ligands in hypercholesterolemic humans.2010

    • Author(s)
      Matsumoto, T., Fujita, M., Sawamura, T., Kakino, A., Sato, Y., Fujita, Y., Matsuda, H., Nakanishi, M., Uchida, K., Nakae, I., Kanda, H., Yoshida, A., Miwa, K., Hayashi, H., Mitsunami, K. and Horie, M.
    • Journal Title

      Lipids

      Volume: 45 Pages: 329-335

    • DOI

      10.1007/s11745-010-3402-7

    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] LOX-1 mediates vascular lipid retention under hypertensive state.2010

    • Author(s)
      Nakano, A., Inoue, N., Sato, Y., Nishimichi, N., Takikawa, K., Fujita, Y., Kakino, A., Otsui, K., Yamaguchi, S., Matsuda, H., Sawamura, T.
    • Journal Title

      J Hypertens

      Volume: 28 Pages: 1273-1280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Dihydrotestosterone suppresses foam cell formation and attenuates atherosclerosis development.2010

    • Author(s)
      Qiu, Y., Yanase, T., Hu, H., Tanaka, T., Nishi, Y., Liu, M., Sueishi, K., Sawamura, T., Nawata, H.
    • Journal Title

      Endocrinology

      Volume: 151 Pages: 3307-3316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Journal Article] Importance of forkhead transcription factor Fkh 118 for development of testicular vasculature.2008

    • Author(s)
      Sato, Y., Baba, T., Zubair, M., Miyabayashi, K., Toyama, Y., Maekawa, M., Owaki, A., Mizusaki, H., Sawamura, T., Toshimori, K., Morohashi, K.I. and Katoh-Fukui, Y.
    • Journal Title

      Mol Reprod Dev (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Electronegative LDL circulating in smokers impairs endothehal progenitor cell differentiation by inhibiting Akt phosphorylation via LOX-1.2008

    • Author(s)
      Tang, D., Lu, J., Walterscheid, J.P., Chen, H.H., Engler, D.A., Sawamura, T., Chang, P. Y., Safi, H.J., Yang, C.Y. and Chen, C.H.
    • Journal Title

      J Lipid Res 49

      Pages: 33-47

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] LOX-1 abrogation reduces myocardial ischemia-reperfusion injury in mice.2008

    • Author(s)
      Hu, C., Chen, J., Dandapat, A., Fujita, Y., Inoue, N., Kawase, Y., Jishage, K., Suzuki, H., Li, D., Hermonat, P.L., Sawamura, T.and Mehta, J.L.
    • Journal Title

      J Mol Cell Cardiol 44

      Pages: 76-83

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Possible involvement of the oxidized low-density lipoprotein/lectin-like oxidized low-density lipoprotein receptor-1 system in pathogenesis and progression of human osteoarthritis.2007

    • Author(s)
      Akagi, M., Kanata, S., Mori, S., Itabe, H., Sawamura, T. and Hamanishi, C.
    • Journal Title

      Osteoarthritis Cartlage 15

      Pages: 281-290

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet.2007

    • Author(s)
      Mehta, J. L., Sanada, N., Hu, C.P., Chen, J., Dandapat, A., Sugawara, F., Satoh, H., Inoue, K., Kawase, Y., Jishage, K., Suzuki, H., Takeya, M., Schnackenberg, L., Beger, R., Hermonat, P. L., Thomas, M. and Sawamura, T.
    • Journal Title

      Circ Res 100

      Pages: 1634-1642

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Modulation of ADP-induced platelet activation by aspirin and pravastatin : role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling.2007

    • Author(s)
      Marwali, M.R., Hu, C.P., Mohandas, B., Dandapat, A., Deonikar, P., Chen, J., Cawich, I., Sawamura, T., Kavdia, M. and Mehta, J.L.
    • Journal Title

      J Pharmacol Exp Ther 322

      Pages: 1324-1332

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Lectin-like oxidized LDL receptor-1 as extracellular chaperone receptor : Its versatile functions and human diseases.2007

    • Author(s)
      Inoue, N. and Sawamura, T.
    • Journal Title

      Methods 43

      Pages: 218-222

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] LOX-1 deletion alters signals of myocardial remodeling immediately after ischemia-reperfuision.2007

    • Author(s)
      Hu, C., Dandapat, A., Chen, J., Fujita, Y., Inoue, N., Kawase, Y., Jishage, K., Suzuki, H., Sawamura, T. and Mehta, J.L.
    • Journal Title

      Cardiovasc Res 76

      Pages: 292-302

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Low-density lipoprotein oxidized to various degrees activates ERK1/2 through LOX-1.2006

    • Author(s)
      Tanigawa, H., Miura, S., Zhang, B., Uehara, Y., Matsuo, Y., Fujino, M., Sawamura, T. and Saku, K.
    • Journal Title

      Atherosclerosis 188

      Pages: 245-250

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Oxidized LDL binding to LOX-1 upregulates VEGF expression in cultured bovine chondrocytes through activation of PPAR-gamma.2006

    • Author(s)
      Kanata, S., Akagi, M., Nishimura, S., Hayakawa, S., Yoshida, K., Sawamura, T., Munakata, H. and Hamanishi, C.
    • Journal Title

      Biochem Biophys Res Commun 348

      Pages: 1003-1010

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Cyclic tensile stretch load and oxidized low density lipoprotein synergistically induce lectin-like oxidized LDL receptor-1 in cultured bovine chondrocytes, resulting in decreased cell viability and proteoglycan synthesis.2006

    • Author(s)
      Akagi, M., Nishimura, S., Yoshida, K., Kakinuma, T., Sawamura, T. Munakata, H. and Hamanishi, C.
    • Journal Title

      J Orthop Res 24

      Pages: 1782-1790

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Dominant-negative LOX-1 blocks homodimenzation of wild-type LOX-1-induced cell proliferation through extracellular signal regulated kinase 1/2 activation.2006

    • Author(s)
      Tanigawa, H., Miura, S., Matsuo, Y., Fujino, M., Sawamura, T. and Saku, K.
    • Journal Title

      Hypertension 48

      Pages: 294-300

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Antioxidants Suppress Plasma Levels of Lectinlike Oxidized Low-Density Lipoprotein Receptor-Ligands and Reduce Atherosclerosis in Watanabe Heritable Hyperlipidemic Rabbits.2006

    • Author(s)
      Oka, K., Yasuhara, M., Suzumura, K., Tanaka, K. and Sawamura, T.
    • Journal Title

      J Cardiovasc Pharmacol 48

      Pages: 177-183

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase.2006

    • Author(s)
      Ma, F. X., Zhou, B., Chen, Z., Ren, Q., Lu, S.H., Sawamura, T. and Han, Z. C.
    • Journal Title

      J Lipid Res 47

      Pages: 1227-1237

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Journal Article] Dynamics and participation of lectin-like oxidized low-density lipoprotein receptor-1(LOX-1) in the development of cardiac allograft vasculopathy2005

    • Author(s)
      Suga M, Sawamura T, Nagaya N, Nakatani T
    • Journal Title

      Transplant International 18(Suppl 1)

      Pages: 33-33

    • Data Source
      KAKENHI-PROJECT-16659376
  • [Journal Article] LOX-1 Unlocked.2005

    • Author(s)
      Sawamura, T.
    • Journal Title

      Structure(Camb) 13

      Pages: 834-835

    • Data Source
      KAKENHI-PROJECT-16390070
  • [Journal Article] LOX-l Unlocked.2005

    • Author(s)
      Sawamura, T.
    • Journal Title

      Structure (Camb) 13

      Pages: 834-835

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390070
  • [Journal Article] LOX-1 Unlocked.2005

    • Author(s)
      Sawamura, T.
    • Journal Title

      Structure (Camb) 13

      Pages: 834-835

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390070
  • [Journal Article] Expression of lectin-like oxidized low-density lipoprotein receptor-1 in allografted hearts2004

    • Author(s)
      Suga M, Sawamura T, Nakatani T, et al.
    • Journal Title

      Transplant Proc 36(8)

      Pages: 2440-2442

    • Data Source
      KAKENHI-PROJECT-16659376
  • [Patent] 融合タンパク質、及びそれを用いた高密度リポタンパク質の測定キット2018

    • Inventor(s)
      沢村達也、垣野明美
    • Industrial Property Rights Holder
      国立大学法人信州大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-024007
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H05249
  • [Patent] 酸化LDL阻害剤2015

    • Inventor(s)
      沢村達也、垣野明美
    • Industrial Property Rights Holder
      国立研究開発法人国立循環器病研究センター、国立大学法人信州大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-08-15
    • Acquisition Date
      2016-02-19
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Patent] LOX-1 阻害活性を高めた後発酵茶精製組成物2014

    • Inventor(s)
      沢村達也、新家康弘、土井聡、來住明宜、松川泰治、
    • Industrial Property Rights Holder
      独立行政法人 国立循環器病研究センター、ユーハ味覚糖株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-001888
    • Filing Date
      2014-01-08
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Patent] 酸化LDL阻害剤2013

    • Inventor(s)
      沢村達也、垣野明美
    • Industrial Property Rights Holder
      国立循環器病研究センター
    • Filing Date
      2013-02-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Patent] 酸化LDL阻害剤2013

    • Inventor(s)
      沢村達也、垣野明美
    • Industrial Property Rights Holder
      沢村達也、垣野明美
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-02-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Patent] 抗血液凝固剤2013

    • Inventor(s)
      沢村達也、藤田佳子、垣野明美
    • Industrial Property Rights Holder
      独立行政法人 国立循環器病研究センター
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-273308
    • Filing Date
      2013-12-27
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Patent] 酸化LDL阻害剤2012

    • Inventor(s)
      沢村達也、垣野明美
    • Industrial Property Rights Holder
      国立循環器病研究センター
    • Industrial Property Number
      2012-027793
    • Filing Date
      2012-02-10
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Patent] 酸化LDL結合阻害剤組成物2011

    • Inventor(s)
      沢村達也、新家康弘
    • Industrial Property Rights Holder
      ユーハ味覚糖株式会社、独立行政法人国立循環器病研究センター
    • Industrial Property Number
      2011-285615
    • Filing Date
      2011-12-27
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Patent] 酸化LDL結合阻害剤2011

    • Inventor(s)
      沢村達也、土井聡
    • Industrial Property Rights Holder
      ユーハ味覚糖株式会社、独立行政法人国立循環器病研究センター
    • Industrial Property Number
      2011-288621
    • Filing Date
      2011-12-28
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Patent] LOX-1アンタゴニスト剤2011

    • Inventor(s)
      沢村達也、新家康弘
    • Industrial Property Rights Holder
      ユーハ味覚糖株式会社、独立行政法人国立循環器病研究センター
    • Industrial Property Number
      2011-236448
    • Filing Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Patent] 緑茶飲料2011

    • Inventor(s)
      沢村達也、松川泰治
    • Industrial Property Rights Holder
      ユーハ味覚糖株式会社、独立行政法人国立循環器病研究センター
    • Industrial Property Number
      2011-122644
    • Filing Date
      2011-05-31
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Patent] 融合タンパク質、核酸、ベクター、細胞、LABの測定方法、並びに、LAB測定用キット2010

    • Inventor(s)
      沢村達也、岩元真
    • Industrial Property Rights Holder
      国立循環器病研究センター、(株)バイオマーカーサイエンス
    • Industrial Property Number
      2010-251701
    • Filing Date
      2010-11-10
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 血清変性HDLと脳卒中発症との関連:鶴岡メタボロームコホート研究.2020

    • Author(s)
      佐田みずき,飯田美穂,垣野明美,原田成,平田あや,桑原和代,杉山大典,宇佐美陽子,藤田佳子,大木宏一,伊澤良兼,高橋愼一,武林亨,沢村達也,岡村智教.
    • Organizer
      第45回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05249
  • [Presentation] 日本の中年男性においてLOX-1 ligand containing ApoAIは冠動脈疾患と関連する.2020

    • Author(s)
      平田あや、垣野明美、岡村智教、門田文、藤吉朗、久松隆史、沢村達也、三浦克之、上島弘嗣.
    • Organizer
      第84回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05249
  • [Presentation] Serum modified HDL was associated with cardiovascular disease in a Japanese community-based cohort.2019

    • Author(s)
      Okamura T, Sata M, Iida M, Kakino A, Harada S, Hirata A, Kuwabara K, Sugiyama D, Sawamura T, Takabayashi T.
    • Organizer
      12th European Public Health Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05249
  • [Presentation] Serum modified HDL levels assessed by a novel assay was associated with coronary artery calcification in an apparently healthy population.2018

    • Author(s)
      Okamura T, Kakino A, Miura K, Fujiyoshi A, Kadota A, Fujita Y, Zaid M, Usami Y, Hisamatsu T, Horiuchi S, Kunimura A, Sugiyama D, Kondo K, Sawamura T and Ueshima H. Serum modified HDL levels assessed by a novel assay was associated with coronary artery calcification in an apparently healthy population.
    • Organizer
      European Society of Cardiology Congress, Munich 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05249
  • [Presentation] 一般住民における飲酒量とHDL-C・変性HDLの関連:神戸研究.2018

    • Author(s)
      平田 匠, 垣野 明美, 東山 綾, 杉山 大典, 久保田 芳美, 西田 陽, 久保 佐智美, 宮松 直美, 宮本 恵宏, 沢村 達也, 岡村 智教.
    • Organizer
      第50回日本動脈硬化学会総会・学術集会(大阪)
    • Data Source
      KAKENHI-PROJECT-16H05249
  • [Presentation] C型慢性肝炎のDAAs治療におけるLDL-Cの変化とPCSK9との関連2018

    • Author(s)
      城下智、杉浦亜弓、梅村武司、沢村達也、太田正穂、田中榮司
    • Organizer
      第115回日本内科学会講演会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] The effect of alcohol drinking and smoking on modified atherogenic high density lipoprotein cholesterol levels in a Japanese general population.2017

    • Author(s)
      Okamura T, Sawamura T, Miura K, Fujiyoshi A, Miyagawa N, Miyamastu N, Ueshima H.
    • Organizer
      European Society for Biomedical Research on Alcoholism Congress 2017, Crete, Greece
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05249
  • [Presentation] 多様な分子との相互作用から明らかになってきたLOX-1の新しい病態生理学的意義2015

    • Author(s)
      沢村達也
    • Organizer
      第10回神戸生活習慣病研究会
    • Place of Presentation
      兵庫県神戸市、ラッセルホール
    • Year and Date
      2015-07-04
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] 多様な分子と相互作用する受容体LOX-1の病態生理学的意義2015

    • Author(s)
      沢村達也
    • Organizer
      第1回 J-ISCP(国際心血管薬物療法学会日本部会)学術集会
    • Place of Presentation
      京都府京都市、ハイアットリージェンシー京都
    • Year and Date
      2015-06-20
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] PAF receptor interacts with LOX-1 and promotes oxidized LDL-induced cellular responses2015

    • Author(s)
      Kakino, A., Fujita, Y., Yamamoto, K., Rakugi, H., Sawamura, T
    • Organizer
      17th International Congress on Atherosclerosis 2015
    • Place of Presentation
      Amsterdam (Holland)
    • Year and Date
      2015-05-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] LOX-1: the receptor for modified LDL and beyond.2015

    • Author(s)
      Tatsuya Sawamura
    • Organizer
      International Symposium:New Era of Lipid and Glycomedicine Research
    • Place of Presentation
      高雄、台湾
    • Year and Date
      2015-03-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] AT1はLOX-1を介した酸化LDLによるシグナル伝達を促進する2015

    • Author(s)
      垣野明美、山本浩一、藤田佳子、楽木宏美、沢村達也
    • Organizer
      第1回J-ISCP学術集会
    • Place of Presentation
      京都府京都市、ハイアットリージェンシー京都
    • Year and Date
      2015-06-20
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] 脳出血とアテローム血栓性脳梗塞における可溶性Lectin-like oxidized LDL receptor-1高値:症例・対照研究2015

    • Author(s)
      横田千晶、沢村達也、渡邊至、小久保喜弘、藤田佳子、垣野明美、中井陸運、豊田一則、宮本恵宏、峰松一夫
    • Organizer
      第27回日本脳循環代謝学会総会
    • Place of Presentation
      富山県富山市、富山国際会議場
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] LOX-1 遺伝子欠損SHRSPの作製とその形質の予備的解析2014

    • Author(s)
      垣野明美、李 蕾、池末昌弘、中野厚史、藤田佳子、岡澤 慎、真下知士、沢村達也
    • Organizer
      第50回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      和歌山県立医科大学 生涯研修センター、和歌山
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] Overexpression of Del-1, An oxidized LDL blocking protein, suppressed atherogenesis in mice without lowering oxidized LDL concentration, but with reducing LOX-1 ligand containing apoB activity (LAB).2014

    • Author(s)
      Akemi. Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura.
    • Organizer
      American Association for Clinical Chemistry Annual Meeting and Clinical Lab Expo
    • Place of Presentation
      Chicago, U.S.A.
    • Year and Date
      2014-07-30
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] AT1 directly interacting with LOX-1 mediates signal transduction induced by oxidized LDL.2014

    • Author(s)
      A. Kakino, K.Yamamoto, A.Nakano, L.Li, Y. Fujita, H.Rakugi, T.Sawamura
    • Organizer
      The 82nd Congress of the European Atherosclerosis Society (EAS 2014)
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2014-06-01
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] 異物受容体としてのLOX-1から見た新展開2013

    • Author(s)
      沢村達也
    • Organizer
      第17回日本心血管内分泌代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] An endogenous blocker of oxidized LDL2013

    • Author(s)
      Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
    • Organizer
      13th International Conference on Endothelin (ET-13)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] Role of lectin-like oxidized low-density of lipoprotein receptor-1 in regulating osteoclastogenesis and inflammatory bone destruction.2013

    • Author(s)
      Nakayachi M, Ito J, Okayasu M, Hayashida C, Sato T, Suda N, Sawamura T, Hakeda
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe Convention Center and Kobe Portpia Hotel, Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-25293376
  • [Presentation] 内因性蛋白質による新しい酸化LDL作用阻害機構 Inhibition of oxidized LDL action by an endogenous protein2013

    • Author(s)
      垣野明美、中野厚史、藤田佳子、沢村達也
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] Lectin-like oxidized low-density of lipoprotein receptor-1 is involved in RANKL-production elevated by lipopolysaccharide-injection on mouse calvaria and thereby contributes to inflammatory bone destruction2013

    • Author(s)
      Nakayachi M, Ito J, Okayasu M, Hayashida C, Sato T, Suda N, Sawamura T, Hakeda Y.
    • Organizer
      35th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Baltimore Convention Center, Baltimore, Maryland, USA
    • Data Source
      KAKENHI-PROJECT-25293376
  • [Presentation] Del-1は酸化LDL-受容体相互作用を阻害し、血管壁脂質沈着を抑制する Del-1 as an endogenous blocker of oxidized LDL which suppresses arterial lipid accumulation2013

    • Author(s)
      垣野明美、中野厚史、藤田佳子、沢村達也
    • Organizer
      第17回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] Identification of Endogenous Anti-Atherogenic Protein Which Blocks the Interaction between Oxidized LDL and Its Receptors2013

    • Author(s)
      Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
    • Organizer
      AHA Scientific Sessions 2013
    • Place of Presentation
      アメリカ・ダラス
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] Regulation Of Cellular Lipid Metabolism In Atherogenesis2013

    • Author(s)
      Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
    • Organizer
      The 81st Congress of the European Atherosclerosis Society (EAS 2013)
    • Place of Presentation
      フランス・リヨン
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] LOX-1 ligands containing apolipoprotein B and catroid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men2013

    • Author(s)
      Tatsuya Sawamura
    • Organizer
      AACC annual meeting&clinical lab expo 2013
    • Place of Presentation
      アメリカ・ヒューストン
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] AT1はLOX-1を介した酸化LDLによるシグナル伝達と血管壁脂質沈着を促進する2013

    • Author(s)
      垣野明美、山本浩一、中野厚史、李蕾、藤田佳子、楽木宏実、沢村達也
    • Organizer
      第49回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] 十年後の脳閉塞を予測する~新規バイオマーカー『LOX-index』~2012

    • Author(s)
      沢村達也
    • Organizer
      第12回日本抗加齢医学会総会 イブニングセミナー
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1とそのリガンドを標的とした心血管病の診断・予防・治療の試み2012

    • Author(s)
      沢村達也
    • Organizer
      関西広域バイオメディカルクラスター成果発表
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Identification of Del-1 as an endogenous oxidized LDL inhibitor2012

    • Author(s)
      垣野明美、藤田佳子、高谷智英、岩元真、沢村達也
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 多機能受容体LOX-1の循環器疾患における役割2012

    • Author(s)
      沢村達也
    • Organizer
      明海大学第350回研修会(第219回大学院総合セミナー共催)
    • Place of Presentation
      埼玉
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Identification of an endogenous inhibitor to block the interaction between oxLDL and its receptors2012

    • Author(s)
      Akemi Kakino, Yoshiko Fujita, Tomohide Takaya, Shin Iwamoto, Tatsuya Sawamura
    • Organizer
      第44回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 十年後の脳閉塞を予測する~新規バイオマーカー『LOX-index』~2012

    • Author(s)
      沢村達也
    • Organizer
      第12回日本抗加齢医学会総会イブニングセミナー
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-23
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Identification of DEL-1 as an endogenous oxidized LDL inhibitor2012

    • Author(s)
      垣野明美、藤田佳子、高谷智英、岩元真、沢村達也
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 心血管機能におけるLOX-1の意義とその診断治療への応用2012

    • Author(s)
      沢村達也
    • Organizer
      第4回酸化LDL勉強会
    • Place of Presentation
      香川
    • Year and Date
      2012-09-28
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1とそのリガンドを標的とした心血管病の診断・予防・治療の試み2012

    • Author(s)
      沢村達也
    • Organizer
      関西広域バイオメディカルクラスター成果発表会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1 研究を支えてくれた人と言葉2012

    • Author(s)
      沢村達也
    • Organizer
      第44回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Elevated Serum Soluble Lectin-like Oxidized LDL Receptor-1 (sLOX1) is Associated With Increased Ischemic Stroke Risk : A Case-control Study. International Stroke Conference2012

    • Author(s)
      Fukuda M, Yokota C, Kokubo Y, Sawamura T, Miyamoto Y, Toyoda K, Minematsu K
    • Organizer
      New Orleans
    • Place of Presentation
      USA
    • Data Source
      KAKENHI-PROJECT-23592110
  • [Presentation] 内因性酸化LDL阻害分子の同定2012

    • Author(s)
      垣野明美、藤田佳子、高谷智英、岩元真、沢村達也
    • Organizer
      第8回宮崎サイエンスキャンプ
    • Place of Presentation
      宮崎
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Serium level of LOX-1 ligand containing apoB (LAB) was associated with an increased risk of subclinical atherosclerosis in us white and Japanese men2012

    • Author(s)
      Okamura, T., Sekikawa, A., Sawamura, T., Kadowaki, T., Tyrrell, K.S., Edmundowicz, D., Murakami, Y., Miura, K., L.Kuller, L.H., Ueshima, H
    • Organizer
      XVI International Symposium on Atherosclerosis
    • Place of Presentation
      シドニー
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 酸化LDL受容体LOX-1の研究からわかったこと2012

    • Author(s)
      沢村達也
    • Organizer
      静岡県立大学薬学月例セミナー
    • Year and Date
      2012-06-11
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] An endogenous oxidized LDL inhibitor DEL-12012

    • Author(s)
      Kakino, A., Fujita, F., Takaya, T., Iwamoto, S., Sawamura, T.
    • Organizer
      XVI International Symposium on Atherosclerosis
    • Place of Presentation
      シドニー
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] ヒト核内受容体PPARαによる生体防御レクチンMBL2の発現制御機構の解析2012

    • Author(s)
      橘敬祐、竹内健太郎、稲田大彦、杉本研、石本憲司、田中十志也、楽木宏実、浜窪隆雄、酒井寿郎、児玉龍彦、沢村達也、土井健史
    • Organizer
      第121回日本薬理学会近畿部会
    • Place of Presentation
      徳島
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 酸化LDL受容体LOX-1の機能を通してわかってきた心血管機能不全のメカニズム2012

    • Author(s)
      沢村達也
    • Organizer
      私立大学戦略的研究基盤形成支援事業・薬学総合研究所サイエンスフォーラム心血管系の老化と疾患に対する研究戦略
    • Place of Presentation
      大阪
    • Year and Date
      2012-10-27
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1研究を支えてくれた人と言葉2012

    • Author(s)
      沢村達也
    • Organizer
      第44回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 変性LDLの考え方2012

    • Author(s)
      沢村達也
    • Organizer
      地域イノベーション戦略支援プログラム 神戸トライアルに関する研究者会議
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 変性LDLの考え方2012

    • Author(s)
      沢村達也
    • Organizer
      地域イノベーション戦略支援プログラム神戸トライアルに関する研究者会議
    • Place of Presentation
      神戸
    • Year and Date
      2012-12-13
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] An endogenous oxidized LDL inhibitor Del-12012

    • Author(s)
      Akemi Kakino, Yoshiko Fujita, Tomohide Takaya, Shin Iwamoto, Tatsuya Sawamura
    • Organizer
      XVI International Symposium on Atherosclerosis
    • Place of Presentation
      シドニー
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Serum level of LOX-1 ligand containing apoB (LAB) was associated with an increased risk of subclinical atherosclerosis in us white and Japanese men2012

    • Author(s)
      Okamura, T., Sekikawa, A., Sawamura, T., Kadowaki,T., Kim Sutton-Tyrrell, Daniel Edmundowicz, Murakami, Y., Miura, K., Lewis H Kuller,Ueshima,H.
    • Organizer
      XVI International Symposium on Atherosclerosis
    • Place of Presentation
      シドニー
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 酸化LDL受容体LOX-1の機能を通してわかってきた心血管機能不全のメカニズム2012

    • Author(s)
      沢村達也
    • Organizer
      私立大学戦略的研究基盤形成支援事業・薬学総合研究所サイエンスフォーラム
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Measurement and manipulation of lox-1 ligand level to predict and to prevent2012

    • Author(s)
      Tatsuva Sawamura
    • Organizer
      17th World Congress on Heart Disease
    • Place of Presentation
      カナダ
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 循環器臨床研究の今後の展望について2012

    • Author(s)
      沢村達也
    • Organizer
      21世紀の循環器医療を考える会
    • Place of Presentation
      京都
    • Year and Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 酸化LDL受容体LOX-1の研究からわかったこと2012

    • Author(s)
      沢村達也
    • Organizer
      静岡県立大学 薬学月例セミナー
    • Place of Presentation
      静岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 血中可溶型LOX-1高値は脳梗塞の発症と関連する2012

    • Author(s)
      福田真弓, 横田千晶, 小久保喜弘, 沢村達也, 宮本恵宏, 豊田一則, 峰松一夫:
    • Organizer
      第37回日本脳卒中学会総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23592110
  • [Presentation] 多機能受容体LOX-1の循環器疾患における役割2012

    • Author(s)
      沢村達也
    • Organizer
      明海大学 第350回研修会(第219回大学院総合セミナー共催)
    • Place of Presentation
      埼玉
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 血管機能における変性LDL受容体LOX-1研究の新しい展開2011

    • Author(s)
      沢村達也
    • Organizer
      第4回最新動脈硬化フォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2011-11-04
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 超高齢化社会への処方隻一酸化LDL受容体研究からの展望2011

    • Author(s)
      沢村達也
    • Organizer
      Bio Japan 2011
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 心不全における左室LOX-1の発現量と可溶型LOX-1の血中濃度は心機能を反映する2011

    • Author(s)
      高谷智英、和田啓道、藤田佳子、森本達也、長谷川浩二、沢村達也
    • Organizer
      第15回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Procyanindin inhibits oxidized LDL binding to LOX-1 and suppresses vascular lipid accumulation in SHRSP rats2011

    • Author(s)
      Ryo Yoshimoto, Taichi Nshizuka, Yoshiko Fujita, Yuko Sato, Atsushi Nakano, Shunji Ohshima, Tomomasa Kanda, Tatsuya Sawamura
    • Organizer
      第43回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 天然物から見出したLOX-1アンタゴニスト・プロシアニジンはSHRSP血管壁への脂質沈着を抑制する2011

    • Author(s)
      垣野明美、西塚太一、藤田佳子、佐藤優子、中野厚史、善本亮、沢村達也
    • Organizer
      第15回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Implication of small dense LDL as a risk for coronary artery disease in a urban Japanese cohort : The Suita study2011

    • Author(s)
      Hidenori Arai, Yoshihiko Kokubo, Makoto Watanabe, Yoshihiro Miyamoto, Tatsuya Sawamura. Tomonori Okamura
    • Organizer
      第43回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Contribution of LOX-1 in the aortic aneurysm and effects of PI polyamide targeting LOX-12011

    • Author(s)
      Ayako Takasaka, Noboru Fukuda, Takahiro Ueno, Akiko Tunemi, Yoshiaki Kusumi, Yukihiko Orime, Motomi Shiono, Tatsuya Sawamura
    • Organizer
      第43回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 高血圧性心不全モデルラットにおける左室LOX-1の発現量は心機能と相関する2011

    • Author(s)
      高谷智英、和田啓道、藤田佳子、森本達也、長谷川浩二、沢村達也
    • Organizer
      第47回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] プロシアニジンはLOX-1アンタゴニストであり、血管壁への脂質沈着を抑制する2011

    • Author(s)
      善本亮、西塚太一、藤田佳子、佐藤優子、中野厚史、垣野明美、大嶋俊二、神田智正、沢村達也
    • Organizer
      第84回日本薬理学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 心不全Dahlラットの心機能低下に伴い左室LOX-1の発現は亢進する2011

    • Author(s)
      高谷智英、和田啓道、藤田佳子、森本達也、沢村達也、長谷川浩二
    • Organizer
      第21回日本循環薬理学会
    • Place of Presentation
      岡山
    • Year and Date
      2011-12-02
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 超高齢化社会への処方箋-酸化LDL受容体研究からの展望2011

    • Author(s)
      沢村達也
    • Organizer
      Bio Japan2011
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 心不全Dah1ラットの心機能低下に伴い左室LOX-1の発現は亢進する2011

    • Author(s)
      高谷智英、和田啓道、藤田佳子、森本達也、沢村達也、長谷川浩二
    • Organizer
      第21回日本循環薬理学会
    • Place of Presentation
      岡山
    • Year and Date
      2011-12-02
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1 in cardiovascular dysfunction2010

    • Author(s)
      Sawamura.T.
    • Organizer
      15th World Cogress on Heart Disease
    • Place of Presentation
      バンクーバー
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1 in cardiovascular dysfunction2010

    • Author(s)
      Sawamura, T.
    • Organizer
      New Frontier in Diagnosis and Management of CV Diseases in 2010
    • Place of Presentation
      Taichung, Taiwan
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] C-Reactive protein binds to LOX-1 and causes vascular dysfunction via complement activation.2010

    • Author(s)
      Fujita, Y., Otsui, K., Kakino, A., Yamaguchi, S., Sato, Y., Yoshimoto, R., Sawamura, T.
    • Organizer
      第14回国際SHRシンポジウム
    • Place of Presentation
      Montreal,Canada
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1 in cardiovascular dysfunction.2010

    • Author(s)
      Sawamura, T.
    • Organizer
      15th World Cogress on Heart Disease
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 酸化LDL測定のための人工標準蛋白作製2010

    • Author(s)
      岩元真、藤田佳子、垣野明美、柳田一樹、善本亮、沢村達也
    • Organizer
      第83回日本生化学会大会、第33回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOχ-l,the oxidized LDL receptor, in cardiovascular dysfunction2010

    • Author(s)
      沢村達也
    • Organizer
      Basic Research Seminar at Texas Heart Institute
    • Place of Presentation
      ヒューストン
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] C-Reactive protein binds to LOX-1 and causes vascular dysfunction via complement activation2010

    • Author(s)
      Fujita, Y., Otsui, K., Kakino, A.,Yamaguchi, S.,Sato, Y., Yoshimoto, R., SawamuraX
    • Organizer
      第14回国際SHRシンポジウム
    • Place of Presentation
      モントリオール
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Recognition of endogenous C-reactive protein by LOX-1 abrogates myocardial infarction.2010

    • Author(s)
      藤田佳子、垣野明美、佐藤優子、善本亮、沢村達也
    • Organizer
      ISHR World Corgress 2010
    • Place of Presentation
      京都
    • Year and Date
      2010-05-13
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1, the oxidized LDL receptor, in cardiovascular dysfunction.2010

    • Author(s)
      沢村達也
    • Organizer
      Basic Research Seminar at Texas Heart Institute
    • Place of Presentation
      Houston, USA
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] The effect of LOX-1 and LOX-1 ligands containing ApoB on the incidence of coronary heart disease and stroke in an 11-year population-based cohort study: The Suita study2010

    • Author(s)
      Okamura, T., Inoue, N., Kokubo, Y, Fujita, Y, Sato, Y., Watanabe, M。Sawamura,T.
    • Organizer
      第42回日本動脈硬化学会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] CRP in LOX-1 Biology2010

    • Author(s)
      沢村達也
    • Organizer
      Workshop on C-Reactive Protein
    • Place of Presentation
      バーミンガム
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1 is involved in the complement activation by endogenous C-Reactive protein and myocardial reperfusion injury2010

    • Author(s)
      Fujita, Y., Otsui, K., Kakino, A.,Yamaguchi, S., Sato,Y., Yoshimoto, R.,Sawamura,T.
    • Organizer
      15th World Cogress on Heart Disease
    • Place of Presentation
      バンクーバー
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] 酸化LDL受容体LOX-1と心血管病2010

    • Author(s)
      沢村達也
    • Organizer
      第3回臨床研究フォーラム
    • Place of Presentation
      静岡
    • Year and Date
      2010-08-06
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] CRP in LOX-1 Biology.2010

    • Author(s)
      沢村達也
    • Organizer
      Workshop on C-Reactive Protein
    • Place of Presentation
      Birmingham, USA
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1 in cardiovascular dysfunction2010

    • Author(s)
      Sawamura, T.
    • Organizer
      New Frontier in Diagnosis and Management of CV Diseases in 2010
    • Place of Presentation
      タイチェン
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] プロシアニジンは酸化LDL受容体LOX-1のアンタゴニストであり、ラット血管壁への脂質沈着を抑制する2010

    • Author(s)
      西塚太一、藤田佳子、佐藤優子、中野厚史、垣野明美、大嶋俊二、神田智正、善本亮、沢村達也
    • Organizer
      第20回日本循環薬理学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] SHR-SPの血管壁脂質沈着におけるLOX-1の役割2010

    • Author(s)
      沢村達也
    • Organizer
      第13回Vitamin E Update Forum
    • Place of Presentation
      東京
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] The effect of LOX-1 and LOX-1 ligands containing ApoB on the incidence of coronary heart disease and stroke in an 11-year population-based cohort study : The Suita study.2010

    • Author(s)
      Okamura, T., Inoue, N., Kokubo, Y., Fujita, Y., Sato, Y., Watanabe, M., Sawamura, T.
    • Organizer
      第42回日本動脈硬化学会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1 is involved in the complement activation by endogenous C-Reactive protein and myocardial reperfusion injury.2010

    • Author(s)
      Fujita, Y., Otsui, K., Kakino, A., Yamaguchi, S., Sato,Y., Yoshimoto, R., Sawamura, T.
    • Organizer
      15th World Cogress on Heart Disease
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] Recognition of endogenous C-reactive protein by LOX-1 abrogates myocardial infarction2010

    • Author(s)
      藤田佳子,垣野明美,佐藤優子,善本亮,沢村達也
    • Organizer
      ISHR World Corgress 2010
    • Place of Presentation
      京都
    • Year and Date
      2010-05-13
    • Data Source
      KAKENHI-PROJECT-22390051
  • [Presentation] LOX-1 as a potential therapeutic target for cardiovascular disease.2007

    • Author(s)
      沢村 達也
    • Organizer
      X IX World Congress of the ISHR
    • Place of Presentation
      Palazzo della Cultura e dei Congressi
    • Year and Date
      2007-06-23
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Presentation] LOX-1 is Involved in high fat diet-induced arterial lipid-deposition in SHR-SP.2007

    • Author(s)
      沢村 達也
    • Organizer
      13th World Congress on Heart Disease
    • Place of Presentation
      The Hyatt Regency Vancouver
    • Year and Date
      2007-07-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Presentation] LOX-1 is Involved in high fat diet-induced arterial lipid-deposition in SHR-SP.2007

    • Author(s)
      Tatsuya Sawamura
    • Organizer
      3th World Congress on Heart Disease
    • Place of Presentation
      The Hyatt Regency Vancouver
    • Year and Date
      2007-07-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Presentation] LOX-1 as a potential therapeutic target for cardiovascular disease.2007

    • Author(s)
      沢村 達也
    • Organizer
      XIX World Congress of the ISHR
    • Place of Presentation
      Palazzo della Cultura e dei Congressi
    • Year and Date
      2007-06-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390078
  • [Presentation] Modified LDL (Serum level of LOX-1 ligand containing ApoB) was associated with increased carotid intima-media thickness in Japanese community dwelling men especially with hypercholesterolemia.

    • Author(s)
      Okamura T, Sawamura T, Hisamatsu T, Fujiyoshi A, Kadota A, Miyamastu N, Miura K, Ueshima H
    • Organizer
      9th World Stroke Congress
    • Place of Presentation
      Istanbul, Turky
    • Year and Date
      2014-10-22 – 2014-10-25
    • Data Source
      KAKENHI-PROJECT-23390178
  • [Presentation] AT1 promotes oxLDL-induced cell responses through interact with LOX-1.

    • Author(s)
      Akemi Kakino, Koichi Yamamoto, Lei Li, Yoshiko Fujita, Hiromi Rakugi, Tatsuya Sawamura
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸国際会議場、神戸
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] Interaction between AT1 and LOX-1 promote oxLDL-induced cell responses.

    • Author(s)
      Akemi Kakino, Koichi Yamamoto, Lei Li, Yoshiko Fujita, Hiromi Rakugi, Tatsuya Sawamura
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場、名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] 酸化LDL阻害分子Del-1の過剰発現は、マウス血管壁脂質沈着を抑制する

    • Author(s)
      垣野明美、中野厚史、藤田佳子、沢村達也
    • Organizer
      第23回日本循環薬理学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] 酸化LDL受容体LOX-1を利用した変性LDL測定方法と動脈硬化性疾患の評価

    • Author(s)
      沢村達也
    • Organizer
      第45回日本臨床検査自動化学会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293063
  • [Presentation] LOX-1は血管内皮障害から動脈硬化性疾患発症を担う

    • Author(s)
      沢村達也
    • Organizer
      第13回日本NO学会学術集会
    • Place of Presentation
      沖縄
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293063
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  • 2.  MAWA Soichi (40157706)
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  • 3.  NINOMIYA Haruaki (80212124)
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  • 4.  KAKINO Akemi (00534637)
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    # of Collaborated Products: 18 results
  • 5.  OKAMURA Tomonori (00324567)
    # of Collaborated Projects: 3 results
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  • 6.  HIGASHIYAMA Aya (20533003)
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  • 7.  FUJITA Yoshiko (30416218)
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  • 12.  OKAYASU Mari (10610941)
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  • 83.  須田 直人
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