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RAKUGI Hiromi  樂木 宏実

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… Alternative Names

RAKUGI HIROMI  楽木 宏実

楽木 宏美  ラクギ ヒロミ

樂木 宏美  ラクギ ヒロミ

楽木 宏実  ラクギ ヒロミ

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Researcher Number 20252679
Other IDs
Affiliation (Current) 2022: 大阪大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2022: 大阪大学, 医学系研究科, 教授
2011 – 2016: 大阪大学, 医学(系)研究科(研究院), 教授
2015: 大阪大学, 大学院医学系研究科 老年・総合内科学, 教授
2015: 大阪大学, 大学院医学系研究科, 教授
2015: 大阪大学, 大学院医学系研究科老年・総合内科学, 教授 … More
2014: 大阪大学大学院医学系研究科, 老年・腎臓内科学, 教授
2013: 大阪大学, 大学院医学系研究科 老年・腎臓内科学, 教授
2013: 大阪大学, 大学院医学系研究科・老年腎臓内科, 教授
2013: 大阪大学, 老年・腎臓内科学, 教授
2012: 大阪大学, 大学院・医学系研究科 老年腎臓内科学, 教授
2012: 大阪大学, 大学院・医学系研究科, 教授
2012: 大阪大学, 大学院・医学系研究科老年・腎臓内科学, 教授
2007 – 2012: Osaka University, Graduate School of Medicine, Professor
2008: 大阪大学, 大学院・医学系研究科, 教授
2006: 大阪大学, 医学系研究科, 助教授
2003 – 2004: 大阪大学, 医学系研究科, 助教授
2002: Osaka University, Graduate School of Medicine, Lecturer, 医学系研究科, 講師
2001: 大阪大学, 医学系研究科, 助手
1999: Osaka University, Medical School Department of Geriatric Medicine Assistant Professor, 医学系研究科, 助手
1994 – 1998: Osaka University, Medical School, Department of Geriatric Medicine, Assistant Pr, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / General internal medicine (including Psychosomatic medicine) / General internal medicine(including psychosomatic medicine) / Experimental pathology / Circulatory organs internal medicine / Basic Section 52010:General internal medicine-related
Except Principal Investigator
General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) / Basic Section 52010:General internal medicine-related / Circulatory organs internal medicine … More / Circulatory organs internal medicine / Metabolomics / General medical chemistry / Medical genome science / Kidney internal medicine / Applied pharmacology / Hygiene and public health / Basic Section 54040:Metabolism and endocrinology-related / Medium-sized Section 53:Organ-based internal medicine and related fields Less
Keywords
Principal Investigator
老化 / Klotho / 動脈硬化 / 遺伝子多型 / 酸化ストレス / サルコペニア / 高血圧 / アンジオテンシン変換酵素 / 虚血性心疾患 / 免疫組織化学 … More / SOD / NO / フレイル / 血管壁再構築 / アンジオテンシン / 伸展刺激 / 分子生物学 / 脳梗塞 / ミトコンドリア / 代謝 / Apop / アポトーシス / 老年医学 / CD9/CD81 DKOマウス / 炎症性サイトカイン / 血管内皮 / ユビキチン系 / 遺伝子機能スクリーニング / 加齢性疾患 / Annexin A1 / ユビキチンシステム / 血管内皮障害 / アンジオテンシンII / キマ-ゼ / マクロファージ / angiotensin-converting / angiotensin / chymase / ischemic heart disease / immunocytochemistry / macrophages / 脈波速度 / 血管内皮機能 / 脳波速度 / atherosclerosis / gene polymorphism / pulse wave velocity / vascular endothelial function / hypertension / 血圧 / ビタミンD / Ca代謝 / PKC / 血管老化 / MnSOD / 一酸化窒素 / 内皮細胞 / cAMP / 血管 / oxidative stress / blood pressure / 脂肪分化 / 接着因子 / 3T3-L1 / 血管内皮細胞 / klotho / siRNA / adipocyte differentiation / adhesion molecle / 3T3-L1 cells / endothelial cells / 高齢癌患者 / 術前評価 / レジスタンス運動 / マイオカイン / 身体トレーニング / 必須アミノ酸 / ACE2 / トリプトファン / 骨格筋 / 小腸 … More
Except Principal Investigator
老化 / 高血圧 / サルコペニア / 遺伝子導入 / 老年医学 / 遺伝子 / アルツハイマー病 / 認知症 / バイオマーカー / 遺伝子治療 / 動脈硬化 / ミトコンドリア / インスリン抵抗性 / 肥満 / 糖尿病 / 認知機能 / アンジオテンシンII / 加齢 / ワクチン / 遺伝子解析 / hypertension / デコイ / NFkB / 生活習慣病 / アンジオテンシン / 降圧薬 / アンジオテンシンII受容体 / 閉塞性睡眠時無呼吸 / マイオカイン / レニン-アンジオテンシン系 / メタボリック症候群 / gene / gene analysis / gene therapy / レニン・アンジオテンシン系 / アンジオテンシノジェン / アンジオテンシンII受容体拮抗薬 / アミノ酸性神経伝達物質 / 吻側延髄腹外側部(RVLM) / オリゴデオキシヌクレオチド / GABA / Amino acid neurotransmitter / Rostral ventrolateral medulla / マクロファージ / 高血糖 / 抗体 / 慢性炎症 / E2F / がん / 悪疫質 / サイトカイン / hTERT / テロメア / 血管内皮細胞 / テロメラーゼ / 分子血管病態学 / アポトーシス / Apop / 脂質異常 / 糖代謝 / アルファシヌクレイン / インスリン抵抗生 / パーキンソン病 / 寿命 / 遺伝素因 / 健康長寿 / ゲノム疫学研究 / 老化関連疾患 / 長寿関連遺伝子 / 一塩基多型 / 心血管疾患 / 後肢懸垂システム / 骨格筋代謝 / アンジオテンシン IV / アンジオテンシン 1-7 / 耐糖能異常 / IRAP / angiotensin IV / angiotensin 1-7 / ACE2 / AngIV / 実験動物 / 組織学的検査 / 骨代謝 / レニン / 酸化LDL受容体 / 細胞内シグナル / 酸化LDL / G蛋白共役型受容体 / 細胞内シグナル伝達経路 / Angiotensin II受容体 / 複合体形成 / Angiotensin II 受容体 / 筋力 / 身体能力 / 睡眠呼吸障害 / 社会医学 / 循環器・高血圧 / 臨床薬理学 / 遺伝子疫学 / 家庭血圧 / HOMED-BP研究 / 降圧反応性 / モデル動物 / ミトコンドリア機能 / 骨格筋エコー / AGE受容体 / レニンーアンジオテンシン系 / AAAAA / 老年病 / 高齢者 / 遺伝子多型 / ADAR遺伝子 / 脂質異常症 / ADAR / 分子遺伝学 / 遺伝子診断 / 分子生物学 / 成因 / 分離生理学 / 高血圧症 / 高血圧自然発症ラット / 多因子疾患 / フォスフォリパーゼ / HYPERTENSION / GENE / MOLECULAR GENETICS / GENE DIAGNOSIS / GENE THERAPY / MOLECULAR BIOLOGY / GENE ANALYSIS / angiotensinogen / hepertension / vascular remodeling / HVJ / グルタミン酸 / グリシン / グルタメート / 延髄腹外側部 / γ-アミノ酪酸 / 腹外側部延髄 / Angiotensin II / Angiotensin receptor antagonist / Hypertension / Glutamate / Glycine / β遮断薬 / HVJ-リポソーム法 / 神経伝達物質 / レニン.アンジオテンシン系 / 血圧調節機構 / β-blocker / Angiotensinogen / Gene introduction / HVJ-liposome method / Oligodeoxynucleotide / Decoy / 遺伝疫学 / 遺伝-環境相互作用 / テーラーメイド医療 / 遺伝子-環境相互作用 / アンジオテンシノージェン遺伝子 / genetic dissection / genetic epidemiology / gene-environmental interaction / renin-angiotensin system / tailor-made medicine / 超高齢者 / 高血圧治療 / 認知機能障害 / フレイル / 管理基準 / FAST / 脳血管障害を伴うアルツハイマー病 / 動物モデル / 脳血管障害 / ADL / 血管障害モデルマウス / FAST分類 / ADL / 軽度認知機能障害 / 血中バイオマーカー / miRNA / CYLD / 脱ユビキチン化酵素 / 血管内皮 / 炎症 / 血管平滑筋 / 石灰化 / インフラマソーム / 内科 / 地域医療 / MSW / 自殺再企図 / 二次予防 / 自殺未遂者 / 病診連携 / 地域連携 / 閉塞性睡眠時無呼吸(OSA) / マイクロRNA(miRNA) / ポリソムノグラフィー(PSG) / 持続陽圧呼吸(CPAP) / ポリソムノグラフィー(PSG) / 持続陽圧呼吸(CPAP) / micro RNA / 糖尿病モデル動物 / SGLT2阻害薬 / myoferlin / 脂肪炎症 / 脂肪分化 / 酸化ストレス / 酸素消費量 / 糖鎖 / アラーミン / 老化細胞 / IL-15 / 運動 / 活性型ビタミンD / 骨粗鬆症 / タウ / 免疫療法 / 伝播 / 高齢者糖尿病 / オートファジー / リソソーム / アンジオテンシン変換酵素2(ACE2) / COVID-19 / SARS-CoV2 / トリプトファン Less
  • Research Projects

    (50 results)
  • Research Products

    (297 results)
  • Co-Researchers

    (87 People)
  •  高齢者糖尿病のオートファジー機能を反映するバイオマーカーの確立と標的治療法の開発

    • Principal Investigator
      高橋 利匡
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  高齢者のCOVID-19感染リスクを安全に低下し得る新規戦略の開発

    • Principal Investigator
      竹下 ひかり
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  タウ病理の脳内進展過程を標的とした認知症の層別化・個別化治療に向けた基盤的研究

    • Principal Investigator
      武田 朱公
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Clarification of the role of Interleukin-15 for the efficacy of exercise on physiological conditions promoting sarcopenia

    • Principal Investigator
      杉本 研
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kawasaki Medical School
  •  ビタミンD補充によるサルコペニア治療の可能性を探る

    • Principal Investigator
      赤坂 憲
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Translational research for regulation of senescence in association with tryptophan metabolismPrincipal Investigator

    • Principal Investigator
      樂木 宏実
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Lysosome-related molecule myoferlin on macrophages in adipose inflammation associated with obesity

    • Principal Investigator
      Takami Yoichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Osaka University
  •  Impact of bisect glycosylation

    • Principal Investigator
      Nakagami Hironori
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Osaka University
  •  Development of novel immunotherapy for chronic inflammatory diseases

    • Principal Investigator
      Nakagami Hironori
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  A comprehensive study related to the effects of improvement of hyperglycemia on skeletal muscle mass and function in older subjects with diabetes

    • Principal Investigator
      SUGIMOTO KEN
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  A comprehensive study related to the mechanism and usefulness of pre-operative intervention on physical frailty as a poor prognostic factor after surgery for gastrointestinal cancer in older adultsPrincipal Investigator

    • Principal Investigator
      Rakugi Hiromi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Exploratory research for biomarkers to diagnose and predict treatment effect in patients with obstructive sleep apnea

    • Principal Investigator
      Ito Norihisa
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Research about optimal target blood pressure in very old population

    • Principal Investigator
      Kamide Kei
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  The development of the clinical course and the animal model of Alzheimer's disease dementia with cerebrovascular disease

    • Principal Investigator
      Takeya Yasushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Exploratory research for plasma biomarkers to predict a future exploratory research in patients with mild cognitive impairment

    • Principal Investigator
      Takeda Masao
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Functional analysis of macrophage CYLD in age-related atherogenesis

    • Principal Investigator
      Takami Yoichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Translational research of therapeutic vaccine to improve the quality of anti-hypertensive therapy

    • Principal Investigator
      Hironori Nakagami
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Basic research for the clinical application of drugs for a life style disease to treat Alzheimer's disease.

    • Principal Investigator
      Yamamoto Koichi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  The elucidation of the mechanism for regulating gene expression in metabolic syndrome in the eldrly.

    • Principal Investigator
      OGURO RYOSUKE
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Prevention of Metabolic syndrome by Apop gene regulation

    • Principal Investigator
      Yasuda Osamu
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      National Institute of Fitness and Sports in Kanoya
      Kumamoto University
  •  Evaluation of hypertension vaccine using pig model

    • Principal Investigator
      NAKAGAMI Hironori
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied pharmacology
    • Research Institution
      Osaka University
  •  Functional screening for novel molecules related to endothelial dysfunction in the ubiquitin system and the potential of their clinical application.Principal Investigator

    • Principal Investigator
      Hiromi Rakugi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Population studies regarding genetic background on progression of hypertension and antihypertensive drug effect based on self-measured home blood pressure

    • Principal Investigator
      Imai Yutaka
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tohoku University
  •  The significance of activation of muscle mitochondrial function in sarcopenic obesity

    • Principal Investigator
      Sugimoto Ken
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  At the attempted suicides of secondary prevention effect of strengthening medical social worker intervention

    • Principal Investigator
      maekawa yoshihiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene and public health
    • Research Institution
      Osaka University
  •  Epigenetic analysis of the dementia progression in the sleep disordered breathing patients

    • Principal Investigator
      ITO Norihisa
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Interaction of cognitive function and glucose metabolism -angiotenisn IV and IRAP system as a new therapeutic target-

    • Principal Investigator
      OHISHI Mitsuru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Kagoshima University
      Osaka University
  •  Cross link between diabetes mellitus and bone metabolism in the aspect of renin angiotensin system

    • Principal Investigator
      SHIMIZU Hideo
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Creation of the anti-aging therapy that assumed Apop gene as a target

    • Principal Investigator
      YASUDA Osamu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Kumamoto University
  •  Is angiotensin II receptor activation involved in the mechanism and pathophysiological role of oxidized LDL?

    • Principal Investigator
      YAMAMOTO Koichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  The establishment of animal model for sarcopenia and clarification of the mechanism of sarcopenia: An investigation using an animal model for chronic obstructive pulmonary diseasesPrincipal Investigator

    • Principal Investigator
      RAKUGI Hiromi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Analysis of novel molecule in aging and metabolism toward translational research

    • Principal Investigator
      NAKAGAMI Hironori
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University
  •  Genetic influence of genes related to aging on successful aging

    • Principal Investigator
      KAMIDE Kei
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical genome science
    • Research Institution
      Osaka University
  •  The role of skeletal muscle metabolism in sarcopenia: An investigation using an animal model for muscle atrophy

    • Principal Investigator
      SUGIMOTO Ken
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Analysis of the ageing mechanism induced by ApopPrincipal Investigator

    • Principal Investigator
      RAKUGI Hiromi
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Analysis of regulatory molecule on vascular aging

    • Principal Investigator
      KATSUYA Tomohiro
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Applied Reserch of Apop protein for the treatment of Atherosclerosis

    • Principal Investigator
      YASUDA Osamu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  The establishment of telomerase control technology and applicationfor medical regeneration

    • Principal Investigator
      ISHIKAWA Kazuhiko
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  The protective effect of Klotho protein from vascular senescence adipocyte differentiation and endothelial functionPrincipal Investigator

    • Principal Investigator
      RAKUGI Hiromi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Functional analysis of senescence related Klotho gene and its application for the therapyPrincipal Investigator

    • Principal Investigator
      RAKUGI Hiromi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  Gene-Enviromental Interaction of Hypertension

    • Principal Investigator
      HIGAKI Jitsuo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Ehime University
  •  Cell biological study on the genetic contribution in human atherosclerosisPrincipal Investigator

    • Principal Investigator
      RAKUGI Hiromi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      OSAKA UNIVERSITY
  •  Evaluation of the role of central neurotrans mitter in animal hypertension models due to hyperactivity of the brain renin-angiotensin system.

    • Principal Investigator
      MIKAMI Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  抗原利用型遺伝子導入法の開発とおとり型核酸医薬を用いたがん遺伝子治療に関する研究

    • Principal Investigator
      OGIHARA Toshio
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Role of vascular angiotensin-generating system in atherosclerosis and acute coronary syndrome : Specifoc role of macrophages and smooth muscle cellsPrincipal Investigator

    • Principal Investigator
      RAKUGI Hiromi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  心血管病におけるアンジオテンシン変換酵素の遺伝子多型とその病態生理的意義の検討Principal Investigator

    • Principal Investigator
      楽木 宏実
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Gene analysis of hypertension and development of new therapy

    • Principal Investigator
      OGIHARA Toshio
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Causative role of amino acids as neurotransmitters in the ventrolateral medulla for the development of hypertension in the rat

    • Principal Investigator
      MIKAMI Hiroshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  高血圧での血管壁再構築における機械的伸展刺激の影響に関する分子機構の研究Principal Investigator

    • Principal Investigator
      樂木 宏美
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Molecular Research of the Etiology and Treatment of Hypertension

    • Principal Investigator
      OGIHARA Toshio
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 Other

All Journal Article Presentation Book

  • [Book] 西村書店2012

    • Author(s)
      樂木宏実
    • Publisher
      高血圧
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] 高齢者の降圧目標と薬剤選択2012

    • Author(s)
      樂木宏実
    • Publisher
      日本医事神新報社
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] 高血圧2012

    • Author(s)
      樂木宏実
    • Publisher
      西村書店
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] アンジオテンシン変換酵素2-アンジオテンシン(1-7)/Masアキシスの基礎的・臨床的意義, 血圧19(1)2012

    • Author(s)
      大石充、楽木宏実
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Book] 内分泌性高血圧診療マニュアル2010

    • Author(s)
      樂木宏実
    • Publisher
      低カリウムを伴う高血圧の鑑別診断
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] 低カリウムを伴う高血圧の鑑別診断、内分泌性高血圧診療マニュアル2010

    • Author(s)
      樂木宏実
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] アンジオテンシン変換酵素(ACE)、内分泌性高血圧診療マニュアル2010

    • Author(s)
      樂木宏実
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] 内分泌性高血圧診療マニュアル2010

    • Author(s)
      樂木宏実
    • Publisher
      アンジオテンシン変換酵素(ACE)
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] 本態性高血圧、「2009今日の治療指針」2010

    • Author(s)
      樂木宏実
    • Total Pages
      3
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] 内分泌性高血圧診療マニュアル2010

    • Author(s)
      樂木宏実
    • Publisher
      高血圧治療ガイドラインと内分泌性高血圧
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] 高血圧治療ガイドラインと内分泌性高血圧、内分泌性高血圧診療マニュアル2010

    • Author(s)
      樂木宏実
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Book] 生体の科学612010

    • Author(s)
      安田修、楽木宏実
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Book] Geriatric Medicine 472009

    • Author(s)
      安田修、楽木宏実
    • Publisher
      ライフ・サイエンス
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] Interleukin‐15 receptor subunit alpha regulates interleukin‐15 localization and protein expression in skeletal muscle cells2022

    • Author(s)
      Yoshida Shino、Fujimoto Taku、Takahashi Toshimasa、Sugimoto Ken、Akasaka Hiroshi、Tanaka Minoru、Huang Yibin、Yasunobe Yukiko、Xie Keyu、Ohnishi Yuri、Minami Tomohiro、Takami Yoichi、Yamamoto Koichi、Rakugi Hiromi
    • Journal Title

      Experimental Physiology

      Volume: 107 Pages: 222-232

    • DOI

      10.1113/ep090205

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07802, KAKENHI-PROJECT-21K17481
  • [Journal Article] Association between uric acid and atherosclerosis in community‐dwelling older people: The <scp>SONIC</scp> study2021

    • Author(s)
      Tanaka Kentaro、Kabayama Mai、Sugimoto Ken、Akasaka Hiroshi、Takami Yoichi、Takeya Yasushi、Yamamoto Koichi、Sekiguchi Toshiaki、Kiyoshige Eri、Akagi Yuya、Godai Kayo、Yasumoto Saori、Masui Yukie、Gondo Yasuyuki、Ikebe Kazunori、Arai Yasumichi、Ishizaki Tatsuro、Rakugi Hiromi、Kamide Kei、the SONIC study group
    • Journal Title

      Geriatrics and Gerontology International

      Volume: 21 Pages: 94-101

    • DOI

      10.1111/ggi.14081

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07888, KAKENHI-PROJECT-20K07803, KAKENHI-PROJECT-18K18456
  • [Journal Article] A pressor dose of angiotensin II has no influence on the angiotensin‐converting enzyme 2 and other molecules associated with SARS‐CoV‐2 infection in mice2021

    • Author(s)
      Wang Yu、Takeshita Hikari、Yamamoto Koichi、Huang Yibin、Wang Cheng、Nakajima Tsuneo、Nozato Yoichi、Fujimoto Taku、Yokoyama Serina、Hongyo Kazuhiro、Nakagami Futoshi、Akasaka Hiroshi、Takami Yoichi、Takeya Yasushi、Sugimoto Ken、Rakugi Hiromi
    • Journal Title

      The FASEB Journal

      Volume: 35

    • DOI

      10.1096/fj.202100016r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03576
  • [Journal Article] Glycemic Control and Insulin Improve Muscle Mass and Gait Speed in Type 2 Diabetes: The MUSCLES-DM Study2021

    • Author(s)
      Sugimoto Ken、Ikegami Hiroshi、Takata Yasunori、Katsuya Tomohiro、Fukuda Masahiro、Akasaka Hiroshi、Tabara Yasuharu、Osawa Haruhiko、Hiromine Yoshihisa、Rakugi Hiromi
    • Journal Title

      Journal of the American Medical Directors Association

      Volume: 22

    • DOI

      10.1016/j.jamda.2020.11.003

    • NAID

      120006952199

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07803, KAKENHI-PROJECT-18K08530, KAKENHI-PROJECT-21H04850, KAKENHI-PROJECT-21K08589
  • [Journal Article] Double Deletion of Angiotensin II Type 2 and Mas Receptors Accelerates Aging‐Related Muscle Weakness in Male Mice2021

    • Author(s)
      Takeshita Hikari、Yamamoto Koichi、Mogi Masaki、Wang Yu、Nozato Yoichi、Fujimoto Taku、Yokoyama Serina、Hongyo Kazuhiro、Nakagami Futoshi、Akasaka Hiroshi、Takami Yoichi、Takeya Yasushi、Sugimoto Ken、Horiuchi Masatsugu、Rakugi Hiromi
    • Journal Title

      Journal of the American Heart Association

      Volume: 10

    • DOI

      10.1161/jaha.120.021030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03576
  • [Journal Article] Novel properties of myoferlin in glucose metabolism via pathways involving modulation of adipose functions.2020

    • Author(s)
      Nozato Y, Takami Y, Yamamoto K, Nagasawa M, Nozato S, Imaizumi Y, Takeshita H, Wang C, Ito Y, Takeda S, Takeya Y, Sugimoto K, Nakagami H, Hanayama R, Rakugi H.
    • Journal Title

      The FASEB Journal

      Volume: 34 Pages: 2792-2811

    • DOI

      10.1096/fj.201901539rr

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08476, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-19H03433
  • [Journal Article] ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-192020

    • Author(s)
      Yamamoto Koichi、Takeshita Hikari、Rakugi Hiromi
    • Journal Title

      Clinical Science

      Volume: 134 Pages: 3047-3062

    • DOI

      10.1042/cs20200486

    • Data Source
      KAKENHI-PROJECT-20H03576
  • [Journal Article] The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice2020

    • Author(s)
      Yoshida S, Nakagami H, Hayashi H, Ikeda Y, Sun J, Tenma A, Tomioka H, Kawano T, Shimamura M, Morishita R, Rakugi H.
    • Journal Title

      Nat Commun

      Volume: 11(1) Pages: 2482-2482

    • DOI

      10.1038/s41467-020-16347-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02730
  • [Journal Article] Overexpression of Interleukin-15 exhibits improved glucose tolerance and promotes GLUT4 translocation via AMP-Activated protein kinase pathway in skeletal muscle2019

    • Author(s)
      Fujimoto Taku、Sugimoto Ken、Takahashi Toshimasa、Yasunobe Yukiko、Xie Keyu、Tanaka Minoru、Ohnishi Yuri、Yoshida Shino、Kurinami Hitomi、Akasaka Hiroshi、Takami Yoichi、Takeya Yasushi、Yamamoto Koichi、Rakugi Hiromi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 509 Pages: 994-1000

    • DOI

      10.1016/j.bbrc.2019.01.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05277, KAKENHI-PROJECT-16K21517
  • [Journal Article] The Usefulness of an Alternative Diagnostic Method for Sarcopenia Using Thickness and Echo Intensity of Lower Leg Muscles in Older Males.2019

    • Author(s)
      Isaka M, Sugimoto K, Yasunobe Y, Akasaka H, Fujimoto T, Kurinami H, Takeya Y, Yamamoto K, Rakugi H
    • Journal Title

      Journal of the American Medical Directors Association

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05277
  • [Journal Article] Preventive effects of low-intensity exercise on cancer cachexia?induced muscle atrophy2019

    • Author(s)
      Tanaka M, Sugimoto K, Fujimoto T, Xie K, Takahashi T, Akasaka H, Kurinami H, Yasunobe Y, Matsumoto T, Fujino H, Rakugi H
    • Journal Title

      The FASEB Journal

      Volume: 27 Pages: 7852-7862

    • DOI

      10.1096/fj.201802430r

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19742, KAKENHI-PROJECT-16H05277, KAKENHI-PROJECT-16K12934, KAKENHI-PROJECT-16K21517, KAKENHI-PROJECT-18H03130, KAKENHI-PROJECT-16K12732, KAKENHI-PROJECT-16H03208
  • [Journal Article] High plasma adiponectin levels are associated with frailty in a general old-old population: The Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians study2018

    • Author(s)
      Nagasawa, M.,Takami, Y.,Akasaka, H.,Kabayama, M.,Maeda, S.,Yokoyama, S.,Fujimoto, T.,Nozato, Y.,Imaizumi, Y.,Takeda, M.,Itoh, N.,Takeya, Y.,Yamamoto, K.,Sugimoto, K.,Nakagawa, T.,Masui, Y.,Arai, Y.,Ishizaki, T.,Ikebe, K.,Gondo, Y.,Kamide, K.,Rakugi, H.
    • Journal Title

      Geriatrics & Gerontology International

      Volume: in press Pages: 839-846

    • DOI

      10.1111/ggi.13258

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15KT0009, KAKENHI-PROJECT-15K08910, KAKENHI-PROJECT-17H02633
  • [Journal Article] Longitudinal Association of Hypertension and Diabetes Mellitus with Cognitive Functioning in a General 70-year-old Population: The SONIC Study.2017

    • Author(s)
      Ryuno H, KamideK, Gondo Y, Kabayama M, Oguro R, Nakama C, Yokoyama S, Nagasawa M, Maeda-Hirao S, Imaizumi Y, Takeya M, Yamamoto H, Takeda M, Takami Y, Itoh N, Takeya Y, Yamamoto K, Sugimoto K, Nakagawa T, Yasumoto S, Ikebe K, Inagaki H, Masui Y, Takayama M, Arai Y, Ishizaki T, Takahashi R, Rakugi H.
    • Journal Title

      Hypertens Res.

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Journal Article] Longitudinal association of hypertension and diabetes mellitus with cognitive functioning in a general 70-year-old population: the SONIC study.2017

    • Author(s)
      Ryuno H, Kamide K, Gondo Y, Kabayama M, Oguro R, Nakama C, Yokoyama S, Nagasawa M, Maeda-Hirao S, Imaizumi Y, Takeya M, Yamamoto H, Takeda M, Takami Y, Itoh N, Takeya Y, Yamamoto K, Sugimoto K, Nakagawa T, Yasumoto S, Ikebe K, Inagaki H, Masui Y, Takayama M, Arai Y, Ishizaki T, Takahashi R, Rakugi H.
    • Journal Title

      Hypertension Research

      Volume: in press Pages: 665-670

    • DOI

      10.1038/hr.2017.15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15KT0009, KAKENHI-PROJECT-17H02633, KAKENHI-PROJECT-15K08910
  • [Journal Article] Factors associated with the severity of obstructive sleep apnea in older adults2017

    • Author(s)
      Kazuhiro Hongyo, Norihisa Ito, Koichi Yamamoto, Yukiko Yasunobe, Masao Takeda, Ryosuke Oguro, Yoichi Takami, Yasushi Takeya, Ken Sugimoto and Hiromi Rakugi
    • Journal Title

      Geriatrics Gerontology International

      Volume: 17 Pages: 614-621

    • DOI

      10.1111/ggi.12768

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Journal Article] Differences of Association between High Blood Pressure and Cognitive Functioning among General Japanese Population Aged 70 and 80 Years: The SONIC Study2016

    • Author(s)
      Ryuno H, Kamide K, Gondo Y, Nakama C, Oguro R, Kabayama M, Kawai T, Kusunoki H, Yokoyama S, Imaizumi Y, Takeya M, Yamamoto H, Takeda M, Takami Y, Itoh N, Yamamoto K, Takeya Y, Sugimoto K, Nakagawa T, Ikebe K, Inagaki H, Masui Y, Ishizaki T, Takayama M, Arai Y, Takahashi R, Rakugi H.
    • Journal Title

      Hypertension Research

      Volume: in press Pages: 557-63

    • DOI

      10.1038/hr.2016.25

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15KT0009, KAKENHI-PROJECT-15K01699, KAKENHI-PROJECT-15K08910, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25780388, KAKENHI-PROJECT-15K11785
  • [Journal Article] Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension2016

    • Author(s)
      Morris BJ1, Chen R2, Donlon TA2, Evans DS3, Tranah GJ3, Parimi N3, Ehret GB4, Newton-Cheh C5, Seto T6, Willcox DC7, Masaki KH8, Kamide K9, Ryuno H10, Oguro R11, Nakama C11, Kabayama M10, Yamamoto K11, Sugimoto K11, Ikebe K12, Masui Y13, Arai Y14, Ishizaki T13, Gondo Y15, Rakugi H11, Willcox BJ8.
    • Journal Title

      American Journal of Hypertension

      Volume: in press Pages: 1292-1300

    • DOI

      10.1093/ajh/hpv171

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KT0009, KAKENHI-PROJECT-15K01699, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-26310104
  • [Journal Article] Effects of calcium channel blocker-based combinations on intra-individual blood pressure variability: post hoc analysis of the COPE trial.2016

    • Author(s)
      Umemoto S, Ogihara T, Matsuzaki M, Rakugi H, Ohashi Y, Saruta T; Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial Group; Combination Therapy of Hypertension to Prevent Cardiovascular Events COPE Trial Group.
    • Journal Title

      HYPERTENSION RESEARCH

      Volume: 39 Pages: 46-53

    • DOI

      10.1038/hr.2015.104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Journal Article] Reply to 'Differences in the association between high blood pressure and cognitive functioning among the general Japanese population aged 70 and 80 years'.2016

    • Author(s)
      Ryuno H, Kamide K, Gondo Y, Kabayama M, Sugimoto K, Ikebe K, Ishizaki T, Arai Y, Rakugi H.
    • Journal Title

      Hypertens Res.

      Volume: 40(3) Pages: 302-303

    • DOI

      10.1038/hr.2016.140

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor2015

    • Author(s)
      Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T and Rakugi H.
    • Journal Title

      THE FASEB JOURNAL

      Volume: Apr 15 Pages: 3342-3356

    • DOI

      10.1096/fj.15-271627

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24601021, KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25670133, KAKENHI-PROJECT-25293063
  • [Journal Article] Awareness of the Japanese Society of Hypertension Guidelines for the Management of Hypertension and their use in clinical practices: 2009 survey results.2015

    • Author(s)
      Obara T, Sergio Ramón Gutiérrez Ubeda, Ohkubo T, MatsuuraH, Ishimitsu T, Takata T, Rakugi H, Imai Y; On behalf of Japanese Society of Hypertension recurrently education committee.
    • Journal Title

      HYPERTENSION RESEARCH

      Volume: - Pages: 400-404

    • DOI

      10.1038/hr.2015.21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790141, KAKENHI-PROJECT-25253059
  • [Journal Article] Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats2015

    • Author(s)
      Koriyama H, Nakagami H, Nakagami F, Osako MK, Kyutoku M, Shimamura M, Kurinami H, Katsuya T, Rakugi H, Morishita R.
    • Journal Title

      Hypertension

      Volume: 66 Pages: 167-174

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Journal Article] Low alpha-synuclein levels in the blood are associated with insulin resistance.2015

    • Author(s)
      Rodriguez-Araujo G, Nakagami H, Takami Y, Katsuya T, Akasaka H, Saitoh S, Shimamoto K, Morishita R, Rakugi H, Kaneda Y.
    • Journal Title

      SCIENTIFIC REPORTS

      Volume: 5 Pages: 12081-12081

    • DOI

      10.1038/srep12081

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Journal Article] Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.2015

    • Author(s)
      N. Kato (他104名, 山本63番目)
    • Journal Title

      Nature Genetics

      Volume: 47 Pages: 1282-1293

    • DOI

      10.1038/ng.3405

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25670353, KAKENHI-PROJECT-25293144, KAKENHI-PROJECT-26293149
  • [Journal Article] Add-on effect of hydrochlorothiazide 12.5 mg in Japanese subjects with essential hypertension uncontrolled with losartan 50 mg and amlodipine 5 mg.2015

    • Author(s)
      Rakugi H, Tsuchihashi T, Shimada K, Numaguchi H, Nishida C, Yamaguchi H, Shirakawa M, Azuma K, Fujita KP.
    • Journal Title

      HYPERTENSION RESEARCH

      Volume: 38 Pages: 329-335

    • DOI

      10.1038/hr.2015.3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Journal Article] Long-term reduction of high blood pressure by angiotensin II DNA vaccine in spontaneously hypertensive rats.2015

    • Author(s)
      Koriyama H, et. al
    • Journal Title

      HYPERTENSION

      Volume: 66 Pages: 167-174

    • DOI

      10.1161/hypertensionaha.114.04534

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461250, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25461127
  • [Journal Article] Novel effect of ezetimibe to inhibit the development of non-alcoholic fatty liver disease in Fatty Liver Shionogi mouse2014

    • Author(s)
      Wang X, Sugimoto K, Fujisawa T, Shindo N, Minato S, Kamada Y, Hamano M, Ohishi M, Ikegami H, Rakugi H
    • Journal Title

      Hepatol Res

      Volume: 44(1) Pages: 102-113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014).2014

    • Author(s)
      Shimamoto K, Hasebe N et al
    • Journal Title

      Hypertens Res. 37:253-387, 2014

      Volume: 37 Pages: 253-387

    • DOI

      10.1038/hr.2014.20

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591031, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25293187
  • [Journal Article] Tissue inhibitor of metalloproteinase-3 knockout mice exhibit enhanced energy expenditure through thermogenesis.2014

    • Author(s)
      Hanaoka Y, Yasuda O, Soejima H, Miyata K, Yamamoto E, Izumiya Y, Maeda N, Ohishi M, Rakugi H, Oike Y, Kim-Mitsuyama S, Ogawa H
    • Journal Title

      PLoS One.

      Volume: 9

    • DOI

      10.1371/journal.pone.0094930

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590886, KAKENHI-PROJECT-24790770, KAKENHI-PROJECT-25461114, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26461364, KAKENHI-PROJECT-26670405
  • [Journal Article] Tissue inhibitor of metalloproteinase-3 knockout mice exhibit enhanced energy expenditure through thermogenesis2014

    • Author(s)
      Hanaoka Y, Yasuda O, Soejima H, Miyata K, Yamamoto E, Izumiya Y, Maeda N, Ohishi M, Rakugi H, Oike Y, Kim-Mitsuyama S, Ogawa H
    • Journal Title

      PLoS One

      Volume: 9(4)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Loss of Angiotensin-converting enzyme 2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice2013

    • Author(s)
      Takeda M, Yamamoto K, Takemura Y, Takeshita H, Hongyo K, Kawai T, Hanasaki-Yamamoto H, Oguro R, Takami Y, Tatara Y, Takeya Y, Sugimoto K, Kamide K, Ohishi M, Rakugi H
    • Journal Title

      Diabetes

      Volume: 62(1) Pages: 223-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Loss of Angiotensin-converting enzyme 2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice2013

    • Author(s)
      4. Takeda M, Yamamoto K, Takemura Y, Takeshita H, Hongyo K, Kawai T, Hanasaki-Yamamoto H, Oguro R, Takami Y, Tatara Y, Takeya Y, Sugimoto K, Kamide K, Ohishi M, Rakugi H.
    • Journal Title

      Diabetes

      Volume: 62 Pages: 223-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Angiotensin (1-7) and other peptides2013

    • Author(s)
      Ohishi M, Yamamoto K, Rakugi H
    • Journal Title

      Current Pharmaceutical Design

      Volume: 19 Pages: 3060-3064

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Telmisartan modulates mitochondrial function in vascular smooth muscle cells2013

    • Author(s)
      Takeuchi K, Yamamoto K, Ohishi M, Takeshita K, Hongyo K, Kawai T, Takeda M, Kamide K, Kurtz TW, Rakugi H
    • Journal Title

      Hypertens Res

      Volume: 36 Pages: 433-439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Angiotensin (1-7) and other AngiotensinPeptides.2013

    • Author(s)
      Ohishi M, Yamamoto K, Rakugi H.
    • Journal Title

      Curr Pharm Des

      Volume: 19 Pages: 3060-3064

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Loss of ACE2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice.2013

    • Author(s)
      Takeda M, Yamamoto K, Takemura Y, Takeshita H, Hongyo K, Kawai T,Hanasaki-Yamamoto H, Oguro R, Takami Y, Tatara Y, Takeya Y, Sugimoto K, Kamide K, Ohishi M, Rakugi H.
    • Journal Title

      Diabetes.

      Volume: 62 Pages: 223-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Analysis ofhepatic gene expression profile in a spontaneous mouse model of type 2 diabetes under a high sucrose diet2013

    • Author(s)
      Nojima K, Sugimoto K, Ueda H, Babaya N, Ikegami H, Rakugi H.
    • Journal Title

      Endocr J.

      Volume: 60 Pages: 261-274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Telmisartan modulates mitochondrial function in vascular smooth muscle cells2013

    • Author(s)
      3. Takeuchi K, Yamamoto K, Ohishi M, Takeshita K, Hongyo K, Kawai T, Takeda M, Kamide K, Kurtz TW, Rakugi H
    • Journal Title

      Hypertension Research

      Volume: 36 Pages: 433-439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Molecular Mechanisms and Implications in Human Health2013

    • Author(s)
      Congrains A, Kamide K, Ohishi M, Rakugi H. ANRIL
    • Journal Title

      nt J Mol Sci.

      Volume: 14 Pages: 1278-1292

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Case report of a long-surviving Werner syndrome patient with severe aortic valve stenosis2012

    • Author(s)
      Kawai T, Yasuda O, et al.(他12名12番目)
    • Journal Title

      Geriatr Gerontol Int

      Volume: 12 Pages: 174-175

    • DOI

      10.1111/j.1447-0594.2011.00748.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300260, KAKENHI-PROJECT-21390222, KAKENHI-PROJECT-23590886
  • [Journal Article] Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.2012

    • Author(s)
      Inoue K, Matsui I, Hamano T, Fujii N, Shimomura A, Nakano C, Kusunoki Y,Takabatake Y, Hirata M, Nishiyama A, Tsubakihara Y, Isaka Y, Rakugi H.
    • Journal Title

      Lab Invest.

      Volume: 92 Pages: 1686-1697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Influence of renin angiotensin system gene polymorphisms on visit-to-visit blood pressure variability in hypertensive patients2012

    • Author(s)
      Kawai T, Ohishi M, Onishi M, Takeya Y, Ito N, Kato N, Yamamoto K, Kamide K, Rakugi H
    • Journal Title

      Am J Hypertens

      Volume: 25(12) Pages: 1249-1255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Pharmacogenomic approaches to study the effects of antihypertensive drugs.2012

    • Author(s)
      Kamide K, Kawano Y, Rakugi H.
    • Journal Title

      Hypertens Res.

      Volume: 35 Pages: 796-799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Genetic Variants at the 9q21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B2012

    • Author(s)
      Congrains CA, Kamide K, Oguro R, Yasuda O, Miyata K, Yamamoto E, Kawai T, Kusunoki H, Yamamoto H, Takeya Y, Yamamoto K, Onishi M, Sugimoto K, Katsuya T, Awata N, Ikebe K, Gondo Y, Oike Y, Ohishi M, Rakugi H
    • Journal Title

      Atherosclerosis

      Volume: 220 Pages: 449-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Screening of Antihypertensive Drugs for Osteoclastic Acid Secretion and Bone Resorption by Acridine Orange2012

    • Author(s)
      Shimizu H, Nakagami H, Yasumasa N, Osako MK, Kyutoku M, Koriyama H, Nakagami F, Shimamura M, Rakugi H, Morishita R
    • Journal Title

      Immun Endoc and Metab Agents in Med Chem

      Volume: 12(3) Pages: 161-167

    • DOI

      10.2174/187152212802001857

    • Data Source
      KAKENHI-PROJECT-23590879
  • [Journal Article] Autophagy guards against cisplatin-induced acutekidney injury.2012

    • Author(s)
      Takahashi A, Kimura T, Takabatake Y, Namba T, Kaimori J, Kitamura H, Matsui I, Niimura F, Matsusaka T, Fujita N, Yoshimori T, Isaka Y, Rakugi H.
    • Journal Title

      Am J Pathol.

      Volume: 180 Pages: 517-525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC2012

    • Author(s)
      Congrains A, Kamide K, Katsuya T, Yasuda O, Oguro R, Yamamoto K, Ohishi M, Rakugi H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 419(4) Pages: 612-616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] A single nucleotide polymorphism of the adenosine deaminase, RNA-specific gene isassociated with the serum triglyceride level, abdominal circumference, and serum adiponectin concentration.2012

    • Author(s)
      Oguro R, Kamide K, Katsuya T, Akasaka H, Sugimoto K, Congrains A, Arai Y, Hirose N, Saitoh S, Ohishi M, Miura T, Rakugi H.
    • Journal Title

      Exp Gerontol.

      Volume: 47 Pages: 183-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Combined use of vitamin D status andFGF23 for risk stratification of renal outcome.2012

    • Author(s)
      Nakano C, Hamano T, Fujii N, Matsui I, Tomida K, Mikami S, Inoue K, Obi Y,Okada N, Tsubakihara Y, Isaka Y, Rakugi H.
    • Journal Title

      Clin J Am Soc Nephrol.

      Volume: 7 Pages: 810-819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Gene polymorphisms contributing to hypertension in immunoglobulin Anephropathy.2012

    • Author(s)
      Shinzawa M, Y amamoto R, Nagasawa Y, Shoji T, Obi Y, Namba T, Kitamura H,Kaneko T, Okada N, Iwatani H, Yamauchi A, Tsubakihara Y, Imai E, Isaka Y, Rakugi H.
    • Journal Title

      Clin Exp Nephrol.

      Volume: 16 Pages: 250-258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC2012

    • Author(s)
      Congrains A, Kamide K, Katsuya T, Yasuda O, Oguro R, Yamamoto K, Ohishi M, Rakugi H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 417 Pages: 612-616

    • Data Source
      KAKENHI-PROJECT-22510211
  • [Journal Article] Evaluation of the efficacy and tolerability of combination therapy with candesartan cilexetil and amlodipine besilate compared with candesartan cilexetil monotherapy and amlodipine besilate monotherapy in Japanese patients with mild-to-moderate essential hypertension: a multicenter, 12-week, randomized, double-blind, placebo-controlled, parallel-group study2012

    • Author(s)
      Rakugi H
    • Journal Title

      Clin Ther

      Volume: 34 Pages: 838-848

    • DOI

      10.1016/j.clinthera.2012.02.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Variations of the Angiotensin II type 1 receptor gene are associated with extreme human longevity2012

    • Author(s)
      Benigni A, Orisio S, Noris M, Iatropoulos P, Castaldi D, Kamide K, Rakugi H, Arai Y, Todeschini M, Ogliari G, Imai E, Gondo Y, Hirose N, Mari D, Remuzzi G
    • Journal Title

      AGE

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22510211
  • [Journal Article] Comparison of the efficacy and safety of azilsartan with that of candesartan cilexetil in Japanese patients with grade I-II essential hypertension: a randomized, double-blind clinical study2012

    • Author(s)
      Rakugi H
    • Journal Title

      Hypertens Res

      Volume: (印刷中) Pages: 552-528

    • DOI

      10.1038/hr.2012.8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] A single nucleotide polymorphism of the adenosine deaminase, RNA-specific gene is associated with the serum triglyceride level, abdominal circumference, and serum adiponectin concentration2012

    • Author(s)
      Oguro R, Kamide K, Katsuya T, Akasaka H, Sugimoto K, Congrains A, Arai Y , Hirose N, Saitoh S, Ohishi M, Miura T, Rakugi H
    • Journal Title

      Exp Gerontol

      Volume: 47 Pages: 183-187

    • Data Source
      KAKENHI-PROJECT-22510211
  • [Journal Article] Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy.2012

    • Author(s)
      Omori H, Kawada N, Inoue K, Ueda Y, Yamamoto R, Matsui I, Kaimori J,Takabatake Y, Moriyama T, Isaka Y, Rakugi H.
    • Journal Title

      Clin Exp Nephrol.

      Volume: 16 Pages: 549-556

    • NAID

      10031058092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Influence of renin angiotensin system gene polymorphisms onvisit-to-visit blood pressure variability in hypertensive patients.2012

    • Author(s)
      Kawai T, Ohishi M, Onishi M, Takeya Y, Ito N, Kato N, Yamamoto K, Kamide K,Rakugi H.
    • Journal Title

      Am J Hypertens.

      Volume: 25 Pages: 1249-1255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B.2012

    • Author(s)
      Congrains A, Kamide K, Oguro R, Yasuda O, Miyata K, Yamamoto E, Kawai T,Kusunoki H, Yamamoto H, Takeya Y, Yamamoto K, Onishi M, Sugimoto K, Katsuya T, Awata N, Ikebe K, Gondo Y, Oike Y, Ohishi M, Rakugi H.
    • Journal Title

      Atherosclerosis

      Volume: 220 Pages: 449-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] CVD-associated non-coding RNA, ANRIL, modulates expression ofatherogenic pathways in VSMC.2012

    • Author(s)
      Congrains A, Kamide K, Katsuya T, Yasuda O, Oguro R, Yamamoto K, Ohishi M, Rakugi H.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 419 Pages: 612-616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Relationship between renal hemodynamic status and aging in patients without diabetes evaluated by renal Doppler ultrasonography.2012

    • Author(s)
      Kawai T, Kamide K, Onishi M, Hongyo K, Yamamoto-Hanasaki H, Oguro R, Maekawa Y, Yamamoto K, Takeya Y, Sugimoto K, Ohishi M, Rakugi H.
    • Journal Title

      Clin Exp Nephrol.

      Volume: 16 Pages: 786-791

    • NAID

      10031122268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC2012

    • Author(s)
      Congrains A
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 417 Pages: 612-616

    • DOI

      10.1016/j.bbrc.2012.02.050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22510211, KAKENHI-PROJECT-23590886
  • [Journal Article] Genetic Variants at the 9p21 Locus Contribute to Atherosclerosis through Modulation of ANRIL and CDKN2A/B2012

    • Author(s)
      Congrains A, Kamide K, Oguro R, Yasuda O, Miyata K, Yamamoto E, Kawai T, Kusunoki H, Yamamoto H, Takeya Y, Yamamoto K, Onishi Y, Sugimoto K, Katsuya T, Awata N, Ikebe K, Gondo Y, Oike Y, Ohishi M, Rakugi H
    • Journal Title

      Atherosclerosis

      Volume: 220 Pages: 445-455

    • Data Source
      KAKENHI-PROJECT-22510211
  • [Journal Article] Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B2012

    • Author(s)
      Congrains, A.(共著)
    • Journal Title

      Atherosclerosis

      Volume: 220 Pages: 449-455

    • DOI

      10.1016/j.atherosclerosis.2011.11.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21330152, KAKENHI-PROJECT-22790111, KAKENHI-PROJECT-23590886, KAKENHI-PROJECT-24653194
  • [Journal Article] Angiotensin-converting enzyme single nucleotide polymorphism is a genetic riskfactor for cardiovascular disease: a cohort study of hypertensive patients.2011

    • Author(s)
      Kato N, Tatara Y, Ohishi M, Takeya Y, Onishi M, Maekawa Y, Rakugi H.
    • Journal Title

      Hypertens Res

      Volume: 34 Pages: 728-734

    • NAID

      10031163244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Klotho protein diminishes endothelial apoptosis and senescence via a mitogen activated kinase pathways2011

    • Author(s)
      Maekawa Y, Ohishi M, Ikushima M, Yamamoto K, Yasuda O, Oguro R, Yamamoto-Hanasaki H, Tatara Y, Takeya Y, Rakugi H
    • Journal Title

      Geriat Gerontrol Int

      Volume: 11(4) Pages: 510-516

    • NAID

      10030468724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Impact of concomitant diabetes and chronic kidney disease on preload-induced changes in left ventricular diastolic filling in hypertensive patients.2011

    • Author(s)
      Iwashima Y, Horio T, Suzuki Y, Takagi T, Kamide K, Ohishi M, Ogihara T, Yoshikawa J, Kawano Y, Rakugi H.
    • Journal Title

      J Hypertens

      Volume: 29 Pages: 144-153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Usefulness of the resistive index in renal Doppler ultrasonography as an indicator of vascular damage in patients with risks of atherosclerosis.2011

    • Author(s)
      Kawai T, Kamide K, Onishi M, Yamamoto-Hanasaki H, Baba Y, Hongyo K, Shimaoka I, Tatara Y, Takeya Y, Ohishi M, Rakugi H.
    • Journal Title

      Nephrol Dial Transplant.

      Volume: 26 Pages: 3256-3262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Klotho protein diminishes endothelial apoptosis and senescence via a mitogen-activated kinase pathway.2011

    • Author(s)
      Maekawa Y, Ohishi M, Ikushima M, Yamamoto K, Yasuda O, Rakugi H.
    • Journal Title

      Geriatr Gerontol Int. in press.

    • NAID

      10030468724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] Klotho protein diminishes endothelial apoptosis and senescence via a mitogen-activated kinase pathway2011

    • Author(s)
      Maekawa Y
    • Journal Title

      Geriatr Gerontol Int

      Volume: 11(4) Pages: 510-516

    • DOI

      10.1111/j.1447-0594.2011.00699.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222, KAKENHI-PROJECT-23590886
  • [Journal Article] Urinary type IV collagen in nondiabetic kidney disease.2011

    • Author(s)
      Furumatsu Y, Nagasawa Y, Shoji T, Yamamoto R, Iio K, Matsui I, Takabatake Y, Kaimori JY, Iwatani H, Kaneko T, Tsubakihara Y, Imai E, Isaka Y, Rakugi H.
    • Journal Title

      Nephron Clin Pract.

      Volume: 117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Crucial role of apoptogenic protein in cellular apoptosis and senescense2011

    • Author(s)
      Yamamoto E, Yasuda O, Fukuo K, Rakugi H, Ogihara T, Ogawa H
    • Journal Title

      Nihon Ronen Igakkai Zasshi

      Volume: 48 Pages: 138-141

    • NAID

      10030469353

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21778628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590886
  • [Journal Article] Angiotensin converting enzyme single nucleotide polymorphism is a genetic risk factor for cardiovascular disease : A cohort study of hypertensive patients2011

    • Author(s)
      Kato N, Tatara Y, Ohishi M, Takeya Y, Onishi M, Maekawa Y, Rakugi H
    • Journal Title

      Hypertens Res

      Volume: 34 Pages: 728-734

    • NAID

      10031163244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Journal Article] Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study.2010

    • Author(s)
      Sugimoto K, Katsuya T, Kamide K, Fujisawa T, Shimaoka I, Ohishi M, Morishita R, Ogihara T, Rakugi H.
    • Journal Title

      Int J Hypertens

      Volume: 2010 Pages: 196307-196307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Comparison of strict- and mild-blood pressure control in elderly hypertensive patients : a per-protocol analysis of JATOS2010

    • Author(s)
      Rakugi H
    • Journal Title

      Hypertens Res

      Volume: 33 Pages: 1124-1128

    • NAID

      10027475856

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Involvement of microsomal triglyceride transfer protein in Inonalcoholic steatohepatitis in novel spontaneous mouse model.2010

    • Author(s)
      Shindo N, Fujisawa T, Sugimoto K, Nojima K, Oze-Fukai A, Yoshikawa Y, Wang X, Yasuda O, Rakugi H.
    • Journal Title

      J Hepatol. 52

      Pages: 903-912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] Additive interaction of metabolic syndrome and chronic kidney disease on cardiac hypertrophy, and risk of cardiovascular disease in hypertension.2010

    • Author(s)
      Iwashima Y, Horio T, Kamide K, RakugiH, Kawano Y, et al
    • Journal Title

      Am J Hypertens 23

      Pages: 290-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice.2010

    • Author(s)
      Shiota A, Yamamoto K, Ohishi M, Tatara Y, Ohnishi M, Maekawa Y, Iwamoto Y, Takeda M, Rakugi H.
    • Journal Title

      Hypertens Res.

      Volume: 33 Pages: 298-307

    • NAID

      10026127523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Accumulation of common polymorphisms is associated with development of hypertension : a 12-year follow-upfrom the Ohasama study2010

    • Author(s)
      Watanabe Y, Metoki H, Rakugi H, Miki T, Imai Y, et al
    • Journal Title

      Hypertens Res 33

      Pages: 129-134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Nifedipine inhibits vascular smooth muscle cell dedifferentiation via downregulation of Akt signaling.2010

    • Author(s)
      Kaimoto T, Yasuda O, Fukuo K, Rakugi H.
    • Journal Title

      Hypertension. 56

      Pages: 247-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] Nifedipine inhibits vascular smooth muscle cell dedifferentiation via downregulation of Akt signaling.2010

    • Author(s)
      Kaimoto T, Yasuda O, Ohishi M, Mogi M, Takemura Y, Suhara T, Ogihara T, FukuoK, Rakugi H.
    • Journal Title

      Hypertension.

      Volume: 56 Pages: 247-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Microarray analysis of tonsils in immunoglobulin A nephropathy patients.2010

    • Author(s)
      Iio K, Nagasawa Y, Iwatani H, Yamamoto R, Rakugi H, et al
    • Journal Title

      Biochem Biophys Res Commun 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Strong suppression of the renin-angiotensin system has arenal-protective effect in hypertensive patients: high-dose ARB with ACEinhibitor (Hawaii) study.2010

    • Author(s)
      Ohishi M, Takeya Y, Tatara Y, Yamamoto K, Onishi M, Maekawa Y, Kamide K,Rakugi H.
    • Journal Title

      Hypertens Res.

      Volume: 33 Pages: 1150-1154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Identification of Evidence Suggestive of an Association with Peripheral Arterial Disease at the OSBPL10 Locus by Genome-Wide Investigation in the Japanese Population.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Sugimoto K, Yamashita H, Takami Y, Maeda S, Kubo M, Takahashi A, Nakamura Y, Ogihara T, Rakugi H, Kaneda Y, Morishita R.
    • Journal Title

      J Atheroscler Thromb

      Volume: 17(10) Pages: 1054-62

    • NAID

      130004845291

    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model.2010

    • Author(s)
      Shindo N, Fujisawa T, Sugimoto K, Nojima K, Oze-Fukai A, Yoshikawa Y, Wang X, Yasuda O, Ikegami H, Rakugi H.
    • Journal Title

      J Hepatol.

      Volume: 52 Pages: 903-912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Variation in OSBPL10 is associated with dyslipidemia2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Morishita R, Rakugi H, 他5名
    • Journal Title

      Hypertension Res.

      Volume: 33 Pages: 511-514

    • NAID

      10026396580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] E-cadherin and claudin-4 expression has circadian rhythm in adult ratkidney2010

    • Author(s)
      Yamato M, Ito T, Iwatani H, Yalnato M, Imai E, Rakugi H, et al
    • Journal Title

      J Nephrol 23

      Pages: 102-110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Specialist care and improved long-term survival of dialysis patients2010

    • Author(s)
      Furumatsu Y, Nagasawa Y, Yamamoto R, Rakugi H, et al
    • Journal Title

      Nephrol Dial Transplant 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Campylobacter fetus peritonitis in a patient with an unused embedded subcutaneous peritoneal catheter.2010

    • Author(s)
      Inoue K, Kitamura H, Nagasawa Y, Kawada N, Isaka Y, Rakugi H.
    • Journal Title

      Perit Dial Int.

      Volume: 30 Pages: 253-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Specialist care and improvedlong-term survival of dialysis patients.2010

    • Author(s)
      Furumatsu Y, Nagasawa Y, Yamamoto R, Iio K, Iwatani H, Matsui I, Takabatake Y, Kawada N, Shoji T, Imai E, Isaka Y, Rakugi H.
    • Journal Title

      Nephrol Dial Transplant.

      Volume: 25 Pages: 1930-1935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Comparison of strictand mild-blood pressure control in elderly hypertensive patients: a per-protocol analysis of JATOS.2010

    • Author(s)
      Rakugi H, Ogihara T, Goto Y, Ishii M; JATOS Study Group.
    • Journal Title

      Hypertens Res.

      Volume: 33 Pages: 1124-1128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice.2010

    • Author(s)
      Shiota A, Yamamoto K, Ohishi M, Tatara Y, Rakugi H, et al
    • Journal Title

      Hypertens Res 印刷中

    • NAID

      10026127523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Variation in OSBPL10 is associated with dyslipidemia.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Akasaka H, Saitoh S, Shimamoto K, Ogihara T, Kaneda Y, Morishita R, Rakugi H.
    • Journal Title

      Hypertens Res

      Volume: 33(5) Pages: 511-4

    • NAID

      10026396580

    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Cardiovascular and Renal Complications of Type 2 Diabetes in Obesity : Role of Sympathetic Nerve Activity and Insulin Resistance2010

    • Author(s)
      Masuo K, Rakugi H, Ogihara T, Esler MD, Lambert GW, et al
    • Journal Title

      Curr Diabetes Rev 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] The counterregulating role of ACE2 andACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation invascular cells.2010

    • Author(s)
      Hayashi N, Yamamoto K, Ohishi M, Tatara Y, Takeya Y, Shiota A, Oguro R,Iwamoto Y, Takeda M, Rakugi H.
    • Journal Title

      Hypertens Res.

      Volume: 33 Pages: 1182-1185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] E-cadherin andclaudin-4 expression has circadian rhythm in adult rat kidney.2010

    • Author(s)
      Yamato M, Ito T, Iwatani H, Yamato M, Imai E, Rakugi H.
    • Journal Title

      J Nephrol

      Volume: 23 Pages: 102-110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Morishita R, Rakugi H, 他5名
    • Journal Title

      J Atheroscler Thromb.

      Volume: 17 Pages: 1054-1062

    • NAID

      130004845291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Estrogen attenuates vascular remodeling in Lp (a) transgenic mice2010

    • Author(s)
      Nakagami F, Nakagami H, Rakugi H, Morishita R, et al
    • Journal Title

      Atherosclerosis 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Microarray analysis of tonsils in immunoglobulin A nephropathy patients.2010

    • Author(s)
      Iio K, Nagasawa Y, Iwatani H, Yamamoto R, Horii A, Okuzaki D, Furumatsu Y, Inohara H, Nojima H, Imai E, Isaka Y, Rakugi H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 393 Pages: 565-570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese2010

    • Author(s)
      Shimaoka I, Kamide K, Ohishi M, Katsuya T, Rakugi H, et al
    • Journal Title

      Hypertens Res 印刷中

    • NAID

      10026126909

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Klotho suppresses TNF-alpha-induced expression of adhesion molecules in the endothelium and attenuates NF-kappaB activation.2009

    • Author(s)
      Maekawa Y, Ishikawa K, Yasuda O, Rakugi H.
    • Journal Title

      Endocrine. 35

      Pages: 341-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] Negative effects of anemia on qualit y of life and its improvement by complete correction of anemia by administration of recombinant human erythropoietin in posttransplant patients.2009

    • Author(s)
      Kawada N, Moriyama T, Rakugi H, Imai E, Takahara S, et al
    • Journal Title

      Clin Exp Nephrol 13

      Pages: 355-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Bc1-2 protects tubular epithelial cells from ischemia/reperfusion injury by dual mechanisms.2009

    • Author(s)
      Isaka Y, Suzuki C, Rakugi H, Shimizu S, Takahara S, et al
    • Journal Title

      Transplant Proc 41

      Pages: 52-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Active vitamin D and its analogue, 22-oxacalcitriol, ameliorate puromycin aminonucleoside-induced nephrosis in rats.2009

    • Author(s)
      Matsui I, Hamano T, Rakugi H, Imai E, Isaka Y, et al
    • Journal Title

      Nephrol Dial Transplant 24

      Pages: 2354-2361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] The impact of diabetes mellituson vitamin D metabolism in predialysis patients.2009

    • Author(s)
      Tanaka H, Hamano T, Fujii N, Tomida K, Matsui I, Mikami S, Nagasawa Y, Ito T,Moriyama T, Horio M, Imai E, Isaka Y, Rakugi H.
    • Journal Title

      Bone.

      Volume: 45 Pages: 949-955

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Effect of interleukin-6 receptor blockage on renal in jury in apolipoprotein E-deficient mice2009

    • Author(s)
      Tomiyama-Hanayama M, Rakugi H, Kohara M, Nishimoto N, et al
    • Journal Title

      Am J Physiol Renal Physiol 279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Validation of Abeta1-40 administration into mouse cerebroventricles as an animal model for Alzheimer disease.2009

    • Author(s)
      Takeda S, Sato N, Rakugi H, Kano M, Morishita R, et al
    • Journal Title

      Brain Res 1280

      Pages: 137-147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] The CXCL12(SDF-1)/CXCR4 axis is essential for the development of renal vasculature.2009

    • Author(s)
      Takabatake Y, Sugiyama T, Kohara H, Rakugi H, Isaka Y, et al
    • Journal Title

      J Am Soc Nephrol 20

      Pages: 1714-1723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Angiotensin receptor blocker prevented beta-amyloid-induced cognitive impairment associated with recovery of neurovascular coupling2009

    • Author(s)
      Takeda S, Sato N, Takeuchi D, Rakugi H, Morishita R, et al
    • Journal Title

      Hypertension 54(6) :

      Pages: 1345-1352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] A novel mouse model for type 2 diabetes and non-alcoholic fatty liver disease : spontaneous amelioration of diabetes by augmented beta cell mass.2009

    • Author(s)
      Oze-Fukai A, Fujisawa T, Sugimoto K, Rakugi H, et al
    • Journal Title

      Endocr J 56

      Pages: 227-234

    • NAID

      10026913000

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Exercise-induced acute kidney injury with reversible posterior leukoencephalopathy syndrome2009

    • Author(s)
      Kimura T, Iio KI, Imai E, Rakugi H, Isaka Y, HayashiT, et al
    • Journal Title

      Clin Exp Nephrol 印刷中

    • NAID

      10027228620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009).2009

    • Author(s)
      Ogihara T, Kikuchi K, Matsuoka H, Fujita T, Rakugi H, et al
    • Journal Title

      Hypertens Res 32

      Pages: 3-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT -IgAN).2009

    • Author(s)
      Yamamoto R, Nagasawa Y, Shoji T, Inoue K, Uehata T, Kaneko T, Okada T, Yamauchi A, Tsubakihara Y, Imai E, Isaka Y, Rakugi H.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 24 Pages: 3686-3694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Quiz page June 2009 : worsening kidney function with a history of urolithiasis.2009

    • Author(s)
      Kimura T, Yasuda K, Obi Y, Rakugi H, Hayashi T, et al
    • Journal Title

      Am J Kidney Dis 53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Prevention of osteoporosis by angiotensin-converting enzyme inhibitor in spontaneous hypertensive r2009

    • Author(s)
      Shimizu H, Nakagami H, Rakugi H, Ogihara T, Morishita R, et al
    • Journal Title

      Hypertens Res 32

      Pages: 786-790

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] A promoter polymorphism of laminA/C gene is an independent genetic predisposition to arterial stiffness in a Japanese general population (the Tanno and Sobetsu study).2009

    • Author(s)
      Akasaka H, Katsuya T, Rakugi H, Ogihara T, Shimamoto K, et al
    • Journal Title

      J Atheroscler Thromb 16

      Pages: 404-409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Klotho Suppresses TNF-a-Induced Expression of Adhesion Molecules in the Endothelium and Attenuates NF-κB Activation2009

    • Author(s)
      Maekawa Y, Ishikawa K, Rakugi H et.al.
    • Journal Title

      Endocrine (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590265
  • [Journal Article] Fluvastatin improves osteoporosis in fructose-fed insulin resistant modelrats through blockade of the classical mevalonate pathway and antioxidant action.2009

    • Author(s)
      Hanayama R, Shimizu H, Nakagami H, Rakugi H, Morishita R, et al
    • Journal Title

      Int J Mol Med 23

      Pages: 581-588

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species2009

    • Author(s)
      Tatara Y, Ohishi M, Yamamoto K, Shiota A, Rakugi H, et al
    • Journal Title

      J Mol Cell Cardiol 47

      Pages: 104-111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to Dlstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN).2009

    • Author(s)
      Yamamoto R, Nagasawa Y, Shoji T, Inoue K, Rakugi H, et al
    • Journal Title

      Nephrol Dial Transplant 24

      Pages: 3686-3694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Fully phosphorylated fetuin-Aforms a mineral complex in the serum of rats with adenineinduced renal failure.2009

    • Author(s)
      Matsui I, Hamano T, Rakugi H, Imai E, Isaka Y, et al
    • Journal Title

      Kidney Int 75

      Pages: 915-928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Fas promoter region gene polymorphism is associated with an increased risk for myocardial in farction2009

    • Author(s)
      Hanasaki H, Takemura Y, Fukuo K, Ohishi M, Rakugi H, et al
    • Journal Title

      Hypertens Res 32

      Pages: 261-264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction.2009

    • Author(s)
      Hanasaki H, Takemura Y, Fukuo K, Ohishi M, Onishi M, Yasuda O, Rakugi H.
    • Journal Title

      Hypertens Res. 32

      Pages: 261-264

    • NAID

      10024830467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] C allele of angiotensin II type 1 receptor gene A1166C polymorphism affbcts plasma adiponectin concentrations in healthy young Japanese women2009

    • Author(s)
      Miyanaga K, Fukuo K, AkasakaRakugi H, Kazumi T, et al
    • Journal Title

      Hypertens Res 32

      Pages: 901-905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Telmisartan-induced inhibition of vascular cell proliferation beyond angiotensin receptor blockade and peroxisome proliferator-activated receptor-gamma activation2009

    • Author(s)
      Yamamoto K, Ohishi M, Ho C, Kurtz TW, Rakugi H, et al
    • Journal Title

      Hypertension 54

      Pages: 1353-1359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Timp-3 deficiency impairs cognitive function in mice.2009

    • Author(s)
      Baba Y, Yasuda O, Fukuo K, Rakugi H.
    • Journal Title

      Lab Invest. 89

      Pages: 1340-1347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] Rationale, study design and implementation of the COLM study : the combination of OLMesartan and calcium channel blocker or diuretic in highrisk elderly hypertensive patients.2009

    • Author(s)
      Ogihara T, Saruta T, Rakugi H, Shimamoto K, Shimada K, et al
    • Journal Title

      Hypertens Res 32

      Pages: 163-167

    • NAID

      10024829854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Timp-3 deficiency impairs cognitive function in mice.2009

    • Author(s)
      Baba Y, Yasuda O, Takemura Y, Ishikawa Y, Ohishi M, Iwanami J, Mogi M, Doe N, Horiuchi M, Maeda N, Fukuo K, Rakugi H.
    • Journal Title

      Lab Invest

      Volume: 89 Pages: 1340-1347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Elevation of plasma beta-amyloid level by glucose loading in Alzheimer mouse models.2009

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R, et al
    • Journal Title

      Biochem Biophys Res Commun 385

      Pages: 193-197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in nondiabetic predialysis CKD patients2009

    • Author(s)
      Tomida K, Hamano T, Mikami S, Fujii N, Rakugi H, et al
    • Journal Title

      Bone 44

      Pages: 678-683

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Timp-3 deficiency impairs cognitive function in mice.2009

    • Author(s)
      Baba Y, Yasuda O, Rakugi H, et al
    • Journal Title

      Lab Invest 89

      Pages: 1340-1347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Usefulness of bone resorption markers in hemodialysis patients2009

    • Author(s)
      Hamano T, Tomida K, Mikami S, Rakugi H, Isaka Y, et al
    • Journal Title

      Bone 45 Suppl 1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Relationship between the achieved blood pressure and the incidence of cardiovascular events in Japanese hypertensive patients with complications : a sub-analysis of the CASE-J trial.2009

    • Author(s)
      Ogihara T, Saruta T, Rakugi H, Higaki J, Nakao K, et al
    • Journal Title

      Hypertens Res 32

      Pages: 248-254

    • NAID

      10024830399

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Klotho suppresses TNF-alpha-induced expression of adhesion molecules in the endothelium and attenuates NF-kappaB activation.2009

    • Author(s)
      Maekawa Y, Ishikawa K, Yasuda O, Oguro R, Hanasaki H, Kida I, Takemura Y,Ohishi M, Katsuya T, Rakugi H.
    • Journal Title

      Endocrine.

      Volume: 35 Pages: 341-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Klotho suppresses TNF-alpha-induced expression of adhesion molecules in the endothelium and attenuatesNF-kappaB activation2009

    • Author(s)
      Maekawa Y, Ishikawa K, Yasuda O, Oguro R, Rakugi H, et al
    • Journal Title

      Endocrine 35

      Pages: 341-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Kid-1 participates in regulating ERK phosphorylation as a part of the circadian clock output in rat kidney.2009

    • Author(s)
      Yamato M, Ishida N, Iwatani H, Yamato M, Rakugi H, Ito T
    • Journal Title

      J Recept Signal Transduct Res 29

      Pages: 94-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Effects of hydroxyhydroquinone-reduced coffee on vasoreactivity and blood pressure2009

    • Author(s)
      Ochiai R, Chikama A, Kataoka K, Rakugi H, Mikami H, et al
    • Journal Title

      Hypertens Res 32

      Pages: 969-974

    • NAID

      10026124231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Association of (pro) renin receptor gene polymorphism with blood pressure in Japanese men : the Ohasama study2009

    • Author(s)
      Hirose T, Hashimoto M, Rakugi H, Takahashi K, Imai Y, et al
    • Journal Title

      Am J Hypertens 22

      Pages: 294-299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] The impact of diabetes mellitus on vitamin D metabolism in predialysis patients2009

    • Author(s)
      Tanaka H, Hamano T, Fujii N, Tomida K, Rakugi H, et al
    • Journal Title

      Bone 45

      Pages: 949-955

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] T elmisartan-induced inhibition of vascular cell proliferation beyond angiotensin receptor blockade and peroxisome proliferator-activated receptor-gamma activation.2009

    • Author(s)
      Yamamoto K, Ohishi M, Ho C, Kurtz TW, Rakugi H.
    • Journal Title

      Hypertension.

      Volume: 54 Pages: 1353-1359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Genetic basis of hypertension for the development of tailored medicine.2009

    • Author(s)
      Katsuya T, Morishita R, Rakugi H, Ogihrara T, et al
    • Journal Title

      Hypertens Res 32

      Pages: 643-648

    • NAID

      10025164481

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Journal Article] Akt activation prevents Apop-1-induced death of cells.2008

    • Author(s)
      Sun X, Yasuda O, Fukuo K, Rakugi H.
    • Journal Title

      Biochem Biophys Res Commun. 77

      Pages: 31097-31101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] Anti-oxidative effect of Klotho on endothelial cells through cAMP activation.2008

    • Author(s)
      Rakugi, H, et. al.
    • Journal Title

      Endocrine 31(1)

      Pages: 82-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590811
  • [Journal Article] A polymorphism regulates CYP4A11 transcriptional activity and is associated with hypertension in a Japanese population.2008

    • Author(s)
      Sugimoto K, Akasaka H, Katsuya T, Node K, Fujisawa T, Shimaoka I, Yasuda O, Rakugi H.
    • Journal Title

      Hypertension. 52

      Pages: 1142-1148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Journal Article] Anti-oxidative effect of Klotho on endothelial cells through cAMP activation2007

    • Author(s)
      H Rakugi, et. al.
    • Journal Title

      Endocrine 31(1)

      Pages: 82-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590265
  • [Journal Article] Anti-oxidative effect of Klotho on endothelial cells through cAMP activation2007

    • Author(s)
      H Rakugi, Ishikawa K, Ogihara T et.al.
    • Journal Title

      Endocrine 31(1)

      Pages: 82-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590265
  • [Journal Article] Anti-oxidative effect of Klotho on endothelial cells through cAMP activation2007

    • Author(s)
      Rakugi H, et. al.
    • Journal Title

      Endocrine 31(1)

      Pages: 82-87

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590811
  • [Journal Article] Anti-oxidative effect of Klotho on endothelial cells through cAMP activation2007

    • Author(s)
      H Rakugi, et. al.
    • Journal Title

      Endocrine 31(1)

      Pages: 82-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590811
  • [Journal Article] Klotho gene delivery suppresses oxidative stress in vivo2007

    • Author(s)
      Ohta J, Rakugi H, Ishikawa K, Ogihara T et.al.
    • Journal Title

      Geriatrics & Gerontology International 7(3)

      Pages: 293-299

    • NAID

      10020021335

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590265
  • [Journal Article] Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells2006

    • Author(s)
      Ikushima M, Rakugi H, Ishikawa K, Ogihara T et.al.
    • Journal Title

      Biochem Biophys Res Commun 339(3)

      Pages: 827-832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590265
  • [Journal Article] Klotho protein promotes adipocyte differentiation2006

    • Author(s)
      Chihara Y, Rakugi H, Ishikawa K, Ogihara T et.al.
    • Journal Title

      Endocrinology 147(8)

      Pages: 3835-3842

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590265
  • [Journal Article] Insulin-mediated regulation of the endothelial renin-angiotensin system and vascular cell growth.2004

    • Author(s)
      Kamide K, Rakugi H, Higaki J, Ogihara T, Tuck M, et al.
    • Journal Title

      Journal of Hypertension 22

      Pages: 121-127

    • Data Source
      KAKENHI-PROJECT-14370226
  • [Presentation] アルツハイマー病のBiological subtypeと髄液バイオマーカーの関連2021

    • Author(s)
      高岡 秀旭,武田 朱公,中嶋 恒男,大山 茜,伊藤 祐規,鷹見 洋一,竹屋 泰,山本 浩一,杉本 研,樂木 宏実,森下 竜一
    • Organizer
      第232回 日本内科学会 近畿地方会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 糖尿病はアルツハイマー病関連タウ蛋白のリン酸化修飾パターンを変化させることで認知機能障害を増悪させる2021

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、竹下 ひかり、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第50回日本心脈管作動物質学会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] アイトラッキング式認知機能評価によるアルツハイマー病バイオマーカー陽性MCIの検出2021

    • Author(s)
      中嶋 恒男、武田 朱公、大山 茜、 伊藤 祐規、鷹見 洋一、竹屋 泰、杉本 研、山本 浩一、樂木 宏実、森下 竜一
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 糖尿病はアルツハイマー病関連タウ蛋白のリン酸化パターンを変化させることで認知機能障害を増悪させる2021

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、竹下 ひかり、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第21回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 糖尿病病態はアルツハイマー病関連タウ蛋白のリン酸化パターンを変化させることで認知機能障害を増悪させる2021

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、竹下 ひかり、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第26回日本基礎理学療法学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 糖尿病はタウのリン酸化パターンの変化を介して認知機能障害を増悪させる2021

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、竹下 ひかり、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 骨格筋におけるIL-15RaによるIL-15調整機構の解明2021

    • Author(s)
      高橋利匡、吉田紫乃、藤本拓、横山世理奈、本行一博、中神太志、赤坂憲、鷹見洋一、杉本研、山本浩一、楽木宏実
    • Organizer
      第57回高血圧関連疾患モデル学会
    • Data Source
      KAKENHI-PROJECT-20K07802
  • [Presentation] アルツハイマー病のサブタイプ分類における脳MRI visual rating scaleの有用性の検討2021

    • Author(s)
      高岡 秀旭,武田 朱公,中嶋 恒男,大山 茜,伊藤 祐規,鷹見 洋一,竹屋 泰,山本 浩一,杉本 研,樂木 宏実,森下 竜一
    • Organizer
      第232回 日本内科学会 近畿地方会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 高精度視線検出技術を用いた定量的認知機能評価法の開発と認知症鑑別診断への応用2021

    • Author(s)
      大山 茜、武田 朱公、伊藤 祐規、中嶋 恒男、鷹見 洋一、竹屋 泰、山本 浩一、杉本 研、片山 泰一、樂木 宏実、森下 竜一
    • Organizer
      第10回日本認知症予防学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 糖尿病はタウ蛋白のリン酸化修飾パターンを変化させることでアルツハイマー病マウスの認知機能障害を増悪させる2021

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、竹下 ひかり、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第10回日本認知症予防学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] アルツハイマー病のBiological subtypeと髄液バイオマーカーの関連2021

    • Author(s)
      武田 朱公、高岡 秀旭、中嶋 恒男、伊藤 祐規、鷹見 洋一、竹屋 泰、山本 浩一、杉本 研、樂木 宏実、森下 竜一
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] アルツハイマー病のBiological subtype分類におけるMRI visual rating scaleの有用性2021

    • Author(s)
      武田 朱公、高岡 秀旭、中嶋 恒男、伊藤 祐規、鷹見 洋一、竹屋 泰、山本 浩一、杉本 研、樂木 宏実、森下 竜一
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 糖尿病はタウのリン酸化パターンを変化させることでアルツハイマー病マウスの認知機能障害を増悪させる2021

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、竹下 ひかり、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第11回日本脳血管・認知症学会総会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 糖尿病はタウのリン酸化パターンの変化を介してアルツハイマー病マウスの認知機能障害を増悪させる2021

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、竹下 ひかり、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      脳心血管抗加齢研究会第17回学術大会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] アイトラッキング式認知機能評価法によるアルツハイマー病バイオマーカー陽性MCIの視線パターン2021

    • Author(s)
      中嶋 恒男、武田 朱公、大山 茜、 伊藤 祐規、鷹見 洋一、竹屋 泰、杉本 研、山本 浩一、樂木 宏実、森下 竜一
    • Organizer
      脳心血管抗加齢研究会第17回学術大会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 髄液Neurofilament値の認知症における病的意義はサブユニット間で異なる2021

    • Author(s)
      高岡 秀旭,武田 朱公,藤岡 智宏,中嶋 恒男,大山 茜,伊藤 祐規,鷹見 洋一,竹屋 泰,山本 浩一,杉本 研,樂木 宏実,森下 竜一
    • Organizer
      第232回 日本内科学会 近畿地方会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 髄液中リン酸化Neurofilament heavy chain濃度と脳白質病変の重症度の関連2021

    • Author(s)
      中嶋 恒男、武田 朱公、大山 茜、 伊藤 祐規、鷹見 洋一、竹屋 泰、杉本 研、山本 浩一、樂木 宏実、森下 竜一
    • Organizer
      第40回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02828
  • [Presentation] 肥満病態におけるMyoferlinの新規機能解明2019

    • Author(s)
      野里陽一、鷹見洋一、山本浩一、中神啓徳、華山力成、楽木宏実
    • Organizer
      第23回日本心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08476
  • [Presentation] 脂肪分化及び肥満形成におけるMyoferlinの機能解明2019

    • Author(s)
      野里陽一、鷹見洋一、山本浩一、中神啓徳、華山力成、楽木宏実
    • Organizer
      第42回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-18K08476
  • [Presentation] Myoferlinは脂肪分化を介して肥満を形成する2018

    • Author(s)
      野里陽一、鷹見洋一、中神啓徳、山本浩一、華山力成、樂木宏実
    • Organizer
      第54回高血圧関連疾患モデル学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08476
  • [Presentation] マイオカインIL-15は骨格筋においてPI3-Akt伝達系を通じてグルコース取り込みを亢進させる2018

    • Author(s)
      藤本拓, 高橋利匡, 安延由紀子, 謝可宇, 田中稔, 栗波仁美, 赤坂憲, 杉本研, 樂木宏実
    • Organizer
      第22回日本心血管内分泌代謝学会
    • Data Source
      KAKENHI-PROJECT-16H05277
  • [Presentation] マイオカインIL-15は骨格筋においてPI3-Akt経路とAMPK経路を介して糖取り込みを亢進させる2018

    • Author(s)
      藤本拓, 杉本研, 高橋利匡, 栗波仁美, 赤坂憲, 樂木宏実
    • Organizer
      第29回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05277
  • [Presentation] 閉塞性睡眠時無呼吸の重症度と関連する血漿中micro RNAの探索2018

    • Author(s)
      伊東範尚 山本浩一 本行一博 鷹見洋一 竹屋泰 杉本研 楽木宏実
    • Organizer
      第7回臨床高血圧フォーラム
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] 加齢性動脈硬化における脱ユビキチン化酵素CYLD(cylindomatosis)の関与2018

    • Author(s)
      鷹見洋一、今泉友希、山本浩一、中神啓徳、楽木宏実
    • Organizer
      第22回 心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 閉塞性睡眠時無呼吸の重症度と関連する血漿中micro RNA の探索2018

    • Author(s)
      伊東範尚、本行一博、永澤元規、武田昌生、赤坂憲、鷹見洋一、竹屋泰、山本浩一、 杉本研、楽木宏実、楽木宏実
    • Organizer
      第7 回臨床高血圧フォーラム
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] Myoferin-mediated lysosomal exocytosis of macophages regulates obesity-induced adipose inflammation2018

    • Author(s)
      Yoichi Nozato, Yoichi Takami, Hironori Nakagami, Koichi Yamamoto, Rikinari Hanayama, Hiromi Rakugi
    • Organizer
      27th Scientific Meeting of the Inernational Society of Hypertension (ISH 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08476
  • [Presentation] 癌悪液質に伴う筋萎縮に対する低強度全身運動が筋タンパク質の合成系経路に与える効果2018

    • Author(s)
      田中稔,杉本研,藤本拓,謝可宇,安延由紀子,高橋利匡, 栗波仁美,赤坂憲,藤野英己,楽木宏実
    • Organizer
      第23回日本基礎理学療法学会学術大会
    • Data Source
      KAKENHI-PROJECT-16H05277
  • [Presentation] 閉塞性睡眠時無呼吸の重症度と関連する血漿中 micro RNA の探索2018

    • Author(s)
      中丸 遼、本行 一博、伊東 範尚山本 浩一、赤坂 憲、鷹見 洋一、竹屋 泰、杉本研、楽木宏実
    • Organizer
      第41 回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] Usefulness of the new index using thickness and echo intensity in a diagnosis of sarcopenia of lower leg muscles2018

    • Author(s)
      Masaaki Isaka, Ken Sugimoto, Yukiko Yasunobe, Minoru Tanaka, Taku Fujimoto, Hiroshi Akasaka, Koichi Yamamoto, Hitomi Kurinami, Yasushi Takeya, Hiromi Rakugi.
    • Organizer
      4th Asian Conference for Frailty and Sarcopeni
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05277
  • [Presentation] 高齢地域住民におけるA/G比と認知機能との関連(SONIC研究)2017

    • Author(s)
      前田聡美,竹屋 泰,赤坂 憲,山本浩一,杉本 研,権藤恭之,石崎達郎,新井康通,神出 計,樂木宏実
    • Organizer
      第59回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 生活習慣病を有する地域一般住民高齢者における喫煙が認知機能に与える影響について:SONIC研究2017

    • Author(s)
      澤山泰佳,樺山 舞,龍野洋慶,杉本 研,権藤恭之,増井幸恵,新井康通,石崎達郎,樂木宏実,神出 計
    • Organizer
      第59回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 高齢者におけるフレイルと血中アディポネクチン濃度についての検討―SONIC研究―2017

    • Author(s)
      永澤元規,鷹見洋一,竹屋 泰,杉本 研,山本浩一,樺山 舞,池邉一典,権藤恭之,神出 計,樂木宏実
    • Organizer
      第59回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] The Association of Blood Pressure with Frailty among Community-Dwelling Older People.2017

    • Author(s)
      Kabayama M,Kamide K,Gondo Y,Sugimoto K,Masui Y,Ishizaki Y,Arai Y,Rakugi H
    • Organizer
      The 21ST IAGG World Congress of Gerontology & Geriatrics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 高齢者における血圧値と認知機能の年代別関連性の検討(SONIC研究)2017

    • Author(s)
      樺山 舞,神出 計,龍野洋慶,権藤恭之,山本浩一,杉本 研,増井幸恵,新井康通,石崎達郎,樂木宏実
    • Organizer
      第59回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 高齢高血圧患者の家庭血圧における起床後高血圧(Zigzag型血圧)に関連する因子の検討2017

    • Author(s)
      本行一博、伊東範尚、栗波仁美、武田昌生、鷹見洋一、杉本 研、竹屋 泰、山本浩一、楽木宏実
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] 高齢高血圧患者の家庭血圧における起床後高血圧に関連する因子の検討2017

    • Author(s)
      伊東 範尚、本行一博、安延由紀子、武田昌生、栗波仁美、鷹見洋一、竹屋 泰、山本浩一、杉本 研、楽木宏実
    • Organizer
      第59回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] 高齢高血圧患者の家庭血圧における起床後高血圧に関連する因子2017

    • Author(s)
      伊東範尚、本行一博、安延由紀子、武田昌生、栗波仁美、竹屋 泰、山本浩一、杉本 研、大塚篤弘、楽木宏実
    • Organizer
      第28回日本老年医学会近畿地方会
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] 地域一般住民高齢者における喫煙と認知機能―生活習慣病の関与:SONIC研究2017

    • Author(s)
      澤山泰佳,樺山 舞,権藤恭之,龍野洋慶,関口敏彰,清重映里,赤木優也,山本浩一,杉本 研,池邉一典,新井康通,増井幸恵,石崎達郎,樂木宏実,神出 計
    • Organizer
      第53回日本循環器病予防学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 高齢高血圧患者の家庭血圧における起床後高血圧に関連する因子の検討2017

    • Author(s)
      本行一博、伊東範尚、栗波仁美、武田昌生、鷹見洋一、杉本 研、竹屋 泰、山本浩一、楽木宏実
    • Organizer
      第6回臨床高血圧フォーラム
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] Genome-wide Association Study of Day-to-day Blood Pressure Variability in Pre-treated Hypertensive Patients: The HOMED-BP Study2016

    • Author(s)
      大久保孝義、佐藤倫広、浅山敬、神出計、田原康玄、尾形宗士郎、杉本研、勝谷友宏、樂木宏実、今井潤、HOMED-BP study group
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      せんだい青葉山交流広場(宮城県仙台市)
    • Year and Date
      2016-03-19
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 高齢者睡眠時無呼吸症候群の重症度に関連する因子の検討2016

    • Author(s)
      本行一博 伊東範尚 山本浩一 安延由紀子 武田昌生 小黒亮輔 鷹見洋一 竹屋泰 杉本研 樂木宏実
    • Organizer
      第58回老年医学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] PIVOTAL ROLES OF DEUBIQIUTINATING ENZYME CYLD (CYLINDROMATOSIS) IN DEVELOPMENT OF AGEING-RELATED ATHEROSCLEROSIS IN THE VASCULATURE.2016

    • Author(s)
      Imaizumi Y, Takami Y, Yamamoto K, Nakagami H, Rakugi H
    • Organizer
      The 26th Scientific Meeting of the International Society of Hypertension
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-09-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 高齢者における重症閉塞性睡眠時無呼吸の関連因子についての検討2016

    • Author(s)
      伊東範尚 山本浩一 本行一博 武田昌生 小黒亮輔 前川佳敬 鷹見洋一 竹屋泰 杉本研 樂木宏実
    • Organizer
      第113回日本内科学会
    • Place of Presentation
      東京
    • Year and Date
      2016-04-15
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] 家庭血圧測定における起床後高血圧と睡眠呼吸障害の有無2016

    • Author(s)
      伊東範尚 本行一博 武田昌生 鷹見洋一 竹屋泰 山本浩一 杉本研 樂木宏実
    • Organizer
      第39回日本高血圧学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-30
    • Data Source
      KAKENHI-PROJECT-16K09238
  • [Presentation] 身体的フレイル指標および高次生活機能をアウトカムとした高齢者高血圧の治療における高圧下限値の検討―SONIC研究2016

    • Author(s)
      樺山 舞,神出 計,龍野洋慶,中間千香子,横山世理奈,永澤元規,平尾聡美,小黒亮輔,山本浩一,杉本 研,樂木宏実
    • Organizer
      第39回日本高血圧学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-30
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 高齢期における動脈硬化進展リスクの検討-SONIC研究3年間の追跡調査からの知見-2015

    • Author(s)
      龍野洋慶,神出 計,中間千香子,樺山 舞,小黒亮輔,横山世理奈,武田昌生,伊東範尚,鷹見洋一,竹屋美幸,竹屋 泰,山本浩一,杉本 研,樂木宏実
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      愛媛県県民文化会館(愛媛県・松山市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(cylindromatosis)の病態生理的役割の検討2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      第57回日本老年医学会学術集会、総会
    • Place of Presentation
      横浜
    • Year and Date
      2015-06-14
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 高齢者における飲酒と血圧の関連(SONIC研究)2015

    • Author(s)
      福崎円香、神出計、樺山舞、龍野洋慶、奈古由美子、清重映里、中間千香子、小黒亮輔、杉本研、池邉一典、石崎達郎、新井康通、権藤恭之、樂木宏実
    • Organizer
      第57回日本老年医学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-06-12
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] Association between Hypertension and Cognitive Function in Age 70 and 80 Years from Japanese SONIC Study2015

    • Author(s)
      Ryuno H, Kamide K, Gondo Y, Oguro R, Nakama C, Ikebe K, Masui Y, Ishizaki T, Arai Y, Rakugi H
    • Organizer
      The International Association of Gerontology and Geriatrics European Region 8th Congress
    • Place of Presentation
      Dublin(Ireland)
    • Year and Date
      2015-04-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 塩分チェックシートを用いた高齢期における高血圧と塩分摂取状況との関連(SONIC研究)2015

    • Author(s)
      龍野洋慶、神出計、樺山舞、渡邉智絵、奈古由美子、福崎円香、清重映里、小黒亮輔、中間千香子、横山世理奈、杉本研、池邉一典、権藤恭之、樂木宏実
    • Organizer
      第4回臨床高血圧フォーラム
    • Place of Presentation
      アクロス福岡(福岡県福岡市)
    • Year and Date
      2015-05-23
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] Association of Longevity Gene Polymorphism, FOXO3A SNP, with Hypertension in Japanese Older Subjects -SONIC Study-2015

    • Author(s)
      Kamide K, Ryuno H, Oguro R, Nakama C, Yokoyama S, Kabayama M, Takeya M, Takeda M, Takami Y, Itoh N, Takeya Y, Yamamoto K, Sugimoto K, Rakugi H
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      愛媛県県民文化会館(愛媛県・松山市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 70歳前期高齢者における高血圧と認知機能低下との関連-SONIC研究3年間の追跡調査からの知見-2015

    • Author(s)
      龍野洋慶、神出計、権藤恭之、小黒亮輔、中間千香子、樺山舞、池邉一典、新井康通、石崎達郎、樂木宏実
    • Organizer
      第26回日本老年医学会近畿地方会
    • Place of Presentation
      京都府立医科大学基礎医学学舎・図書館ホール(京都府京都市)
    • Year and Date
      2015-11-14
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] サルコペニア肥満の定義と意義に関する検討2015

    • Author(s)
      杉本 研、王 中奇、藤本 拓、竹屋 泰、山本浩一、楽木宏実
    • Organizer
      第19回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-25460897
  • [Presentation] 70歳前期高齢者における高血圧と認知機能低下との関連-SONIC研究3年間の追跡調査からの知見-2015

    • Author(s)
      龍野洋慶,神出 計,権藤恭之,小黒亮輔,中間千香子,樺山 舞,池邉一典,新井康通,石崎達郎,樂木宏実
    • Organizer
      第26回日本老年医学会近畿地方会
    • Place of Presentation
      京都府立医科大学(京都府・京都市)
    • Year and Date
      2015-11-14
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 高齢者高血圧治療における降圧薬感受性遺伝子の関与-SONIC研究-2015

    • Author(s)
      神出計、小栗亮輔、中間千香子、横山世里奈、龍野洋慶、樺山舞、杉本研、池邉一典、権藤恭之、樂木宏実
    • Organizer
      第57回日本老年医学会学術集会・総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-06-13
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 高齢者糖尿病患者におけるサルコペニアの頻度とその意義2015

    • Author(s)
      杉本 研、中間千香子、王 中奇、藤本 拓、竹屋 泰、山本浩一、楽木宏実
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      下関
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25460897
  • [Presentation] 高齢者における高血圧と認知機能との関連-服薬アドヒアランスの影響:SONIC研究-2015

    • Author(s)
      龍野洋慶、神出計、権藤恭之、小黒亮輔、中間千香子、横山世理奈、中川威、樺山舞、杉本研、池邉一典、新井康通、増井幸恵、石崎達郎、樂木宏実
    • Organizer
      第51回日本循環器病予防学会学術集会
    • Place of Presentation
      大阪大学中之島センター(大阪府大阪市)
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(cylindromatosis)の病態生理的役割の検討2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      松山
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] Association of Longevity Gene Polymorphism, FOXO3A SNP, with Hypertension in Japanese Older Subjects -SONIC Study-2015

    • Author(s)
      Kamide K, Ryuno H, Oguro R, Nakama C, Yokoyama S, Kabayama M, Takeya M, Takeda M, Takami Y, Itoh N, Takeya Y, Yamamoto K, Sugimoto K, Rakugi H
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      愛媛県県民文化会館(愛媛県松山市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] Effects of Anti-hypertensive Medication on Cognitive Function in Older Subjects: The SONIC Study2015

    • Author(s)
      Ryuno H, Kamide K, Gondo Y, Nakama C, Oguro R, Kabayama M, Ikebe K, Masui Y, Inagaki H, Ishizaki T, Arai Y, Rakugi H
    • Organizer
      The International Association of Gerontology and Geriatrics European Region 8th Congress
    • Place of Presentation
      Dublin (Ireland)
    • Year and Date
      2015-04-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 加齢に伴う動脈硬化形成過程における脱ユビキチン化酵素CYLD(cylindromatosis)のマクロファージの泡沫化への影響2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      CVMW2015心血管代謝週間
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(cylindromatosis)の病態生理的役割の検討2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      第51回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 高齢者における高血圧と認知機能との関連-服薬アドヒアランスの影響:SONIC研究-2015

    • Author(s)
      龍野洋慶,神出 計,権藤恭之,小黒亮輔,中間千香子,樺山 舞,池邉一典,新井康通,石崎達郎,樂木宏実
    • Organizer
      第57回日本老年医学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2015-06-12
    • Data Source
      KAKENHI-PROJECT-15K08910
  • [Presentation] 古典的な血圧関連遺伝子の現在における位置づけについて2015

    • Author(s)
      勝谷友宏、森下竜一、樂木宏実
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      愛媛県県民文化会館(愛媛県松山市)
    • Year and Date
      2015-10-11
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 加齢に伴う動脈硬化形成過程における脱ユビキチン化酵素CYLD(cylindromatosis)のマクロファージの泡沫化への影響2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      12月 第10回 高血圧と冠動脈疾患研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-12-19
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 高齢期における動脈硬化進展リスクの検討-SONIC研究3年間の追跡調査からの知見-2015

    • Author(s)
      龍野洋慶、神出計、中間千香子、樺山舞、小黒亮輔、横山世理奈、武田昌生、伊東範尚、鷹見洋一、竹屋美幸、竹屋泰、山本浩一、杉本研、樂木宏実
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      愛媛県県民文化会館(愛媛県松山市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 高齢者における高血圧と認知機能との関連-服薬アドヒアランスの影響:SONIC研究-2015

    • Author(s)
      龍野洋慶、神出計、権藤恭之、小黒亮輔、中間千香子、樺山舞、池邉一典、新井康通、石崎達郎、樂木宏実
    • Organizer
      第57回日本老年医学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-06-12
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 高齢者高血圧と認知機能障害の関連における降圧薬の影響-SONIC研究-2014

    • Author(s)
      龍野洋慶,神出 計,小黒亮輔,中間千香子,樺山 舞,河合達男,竹屋 泰,山本浩一,杉本 研,樂木宏実
    • Organizer
      第37回日本高血圧学会総会
    • Place of Presentation
      パシフィコ横浜( 神奈川県横浜市)
    • Year and Date
      2014-10-19
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 高齢者における高血圧とフレイルとの関連-SONIC研究2014

    • Author(s)
      中間千香子,杉本研,神出 計,小黒亮輔,龍野洋慶,樺山 舞,樂木宏実
    • Organizer
      第37回日本高血圧学会総会
    • Place of Presentation
      パシフィコ横浜( 神奈川県横浜市)
    • Year and Date
      2014-10-19
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 高齢者における生活習慣病と認知機能障害との関連性-SONIC研究-2014

    • Author(s)
      龍野洋慶,神出 計,権藤恭之,小黒亮輔,中間千香子,樺山 舞,竹屋 泰,山本浩一,杉本 研,池邉一典,荒井康通,増井幸恵,高橋龍太郎,楽木宏実
    • Organizer
      第3回臨床高血圧フォーラム
    • Place of Presentation
      広島国際会議場( 広島県広島市)
    • Year and Date
      2014-05-24
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 百寿者の動脈硬化と血圧値の検討-70歳、80歳との比較検討 SONIC研究-2013

    • Author(s)
      神出 計,小黒亮輔,中間千香子,立平由紀子,中川 威,山本浩一,杉本 研,池邉一典,権藤恭之,楽木宏実
    • Organizer
      第24回日本老年医学会近畿地方会
    • Place of Presentation
      京都大学医学部芝蘭会館 (京都府京都市)
    • Year and Date
      2013-11-16
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 多様な老化表現型を示す新たな老化モデル:テトラスパニンCD9/CD81 二重欠損マウス2013

    • Author(s)
      武田吉人、金 英姫、杉本 研、熊ノ郷淳、楽木宏実
    • Organizer
      第55回日本老年医学会総会
    • Year and Date
      2013-06-05
    • Data Source
      KAKENHI-PROJECT-23659379
  • [Presentation] 高齢者における高血圧と認知機能障害との関連性-SONIC研究-2013

    • Author(s)
      龍野洋慶,神出 計,権藤恭之,小黒亮輔,中間千香子,樺山 舞,竹屋 泰,山本浩一,杉本 研,池邉一典,荒井康通,増井幸恵,高橋龍太郎,楽木宏実
    • Organizer
      第36回日本高血圧学会総会
    • Place of Presentation
      大阪国際会議場( 大阪府大阪市)
    • Year and Date
      2013-10-25
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] Apop Gene Expression is Implicated in the Senescence of Vascular Endothelial Cells Induced by High Glucose2012

    • Author(s)
      Yasuda O, Yamamoto E, Soejima H, Hanaoka Y, Rakugi H, Kim-Mitsuyama S, Ogawa H
    • Organizer
      76th Japanese Circulation Society
    • Place of Presentation
      Fukuoka International Congress Center, Fukuoka
    • Data Source
      KAKENHI-PROJECT-23590886
  • [Presentation] 新規降圧薬の開発2012

    • Author(s)
      樂木宏実
    • Organizer
      第一回臨床高血圧フォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2012-05-12
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] Effect of azilsartan on the circadian rhythm of blood pressure in Japanese essential hypertension2012

    • Author(s)
      Rakugi H
    • Organizer
      Abstracts of the 24th Meeting of the Internal Society of Hypertension
    • Place of Presentation
      Sydney
    • Year and Date
      2012-10-03
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 日本 JSH20092012

    • Author(s)
      樂木宏実
    • Organizer
      第35回日本高血圧学会総
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-22
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 高齢者高血圧の血圧正常化の有用性と安全性:VALISH研究サブ解析2012

    • Author(s)
      樂木宏実
    • Organizer
      第35回日本高血圧学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 高血圧制圧の戦略:新規降圧療法の開発2012

    • Author(s)
      樂木宏実
    • Organizer
      第35回日本高血圧学会総会
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 日本JSH20092012

    • Author(s)
      樂木宏実
    • Organizer
      第35回日本高血圧学会総会
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 降圧以上にぷらあすアルファの効果は本当にあるのか?2012

    • Author(s)
      樂木宏実
    • Organizer
      第33回日本臨床薬理学会学術総会
    • Place of Presentation
      沖縄
    • Invited
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 実地医家の教育2012

    • Author(s)
      樂木宏実
    • Organizer
      第54回日本老年医学会学術集会・総会
    • Place of Presentation
      東京
    • Year and Date
      2012-06-30
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 降圧薬の多面的効果、骨代謝改善作用について2012

    • Author(s)
      志水秀郎、中神啓徳、楽木宏実、森下隆一
    • Organizer
      アンチエイジングフェスタ2012
    • Place of Presentation
      大阪市
    • Year and Date
      2012-11-17
    • Data Source
      KAKENHI-PROJECT-23590879
  • [Presentation] 健康長寿診療ハンドブックと高齢期の疾病・介護の予防2012

    • Author(s)
      樂木宏実
    • Organizer
      第19回日本未病システム学会
    • Place of Presentation
      金沢
    • Year and Date
      2012-10-28
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 降圧薬の多面的効果、骨代謝改善作用について2012

    • Author(s)
      志水秀郎、中神啓徳、楽木宏実、森下隆一
    • Organizer
      アンチエイジングフェスタ(脳心血管加齢研究会)
    • Place of Presentation
      大阪(ハービスホール)
    • Data Source
      KAKENHI-PROJECT-23590879
  • [Presentation] 高齢者高血圧の血圧正常化の有用性と安全性:VALISH 研究サブ解析2012

    • Author(s)
      樂木宏実
    • Organizer
      第35回日本高血圧学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 高血圧制圧の戦略:新規降圧療法の開発2012

    • Author(s)
      樂木宏実
    • Organizer
      第35回日本高血圧学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] Combination therapy in hypertension with CKD2012

    • Author(s)
      Rakugi H
    • Organizer
      Abstracts of the 24th Meeting of the Internal Society of Hypertension
    • Place of Presentation
      Sydney
    • Year and Date
      2012-10-02
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 降圧以上にぷらあすアルファの効果は本当にあるのか?2012

    • Author(s)
      樂木宏実
    • Organizer
      第33回日本臨床薬理学会学術総会
    • Place of Presentation
      沖縄
    • Year and Date
      2012-11-03
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 高齢者と高血圧治療2012

    • Author(s)
      樂木宏実
    • Organizer
      第54回日本老年医学会学術集会・総会
    • Place of Presentation
      東京
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] VALISH: The valsartan in elderly isolated systolic hypertension study2012

    • Author(s)
      樂木宏実
    • Organizer
      第35回日本高血圧学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] ハンドブックが目指すもの:編集者の立場から2012

    • Author(s)
      樂木宏実
    • Organizer
      第54回日本老年医学会学術集会・総会
    • Place of Presentation
      東京
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] ハンドブックが目指すもの:編集者の立場から2012

    • Author(s)
      樂木宏実
    • Organizer
      第54回日本老年医学会学術集会・総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] Implication of Apop, a Novel Mitochondrial Protein, in the Mitochondrial Oxidative Stress Production2011

    • Author(s)
      Yasuda O, Yamamoto E, Ohishi M, Kim-Mitsuyama S, Rakugi H, Ogawa H
    • Organizer
      75th Japanese Circulation Society
    • Place of Presentation
      Pacifico Yokohama, Yokohama
    • Data Source
      KAKENHI-PROJECT-23590886
  • [Presentation] 骨代謝に対するアンジオテンシン受容体拮抗薬の効果2011

    • Author(s)
      志水秀郎、中神啓徳、大石充、楽木宏実、森下竜一
    • Organizer
      第22回日本老年病学会近畿地方会
    • Place of Presentation
      兵庫医科大学
    • Data Source
      KAKENHI-PROJECT-23590879
  • [Presentation] 生活習慣病が骨格筋に及ぼす影響:自然発症高血圧ラット(SHR)を用いた検討2011

    • Author(s)
      杉本 研、楽木宏実
    • Organizer
      第22回日本老年病学会近畿地方会
    • Place of Presentation
      神戸
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-23659379
  • [Presentation] ACE2/Angiotensin(1-7)/mas軸の最新知見2011

    • Author(s)
      大石充、楽木宏実
    • Organizer
      第40回日本心脈管作動物質学会
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-23590877
  • [Presentation] 本態性高血圧-成因・診断・治療-2010

    • Author(s)
      樂木宏実
    • Organizer
      老年医学会 北陸地方会
    • Place of Presentation
      福井
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 本態性高血圧-成因・診断・治療-2010

    • Author(s)
      樂木宏実
    • Organizer
      老年医学会 北陸地方会
    • Place of Presentation
      福井(招待講演)
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 糖尿病患者の高血圧治療と糖尿病発症予防の高血圧治療2010

    • Author(s)
      樂木宏実
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] VALISH からのレッスン2010

    • Author(s)
      樂木宏実
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 高血圧と血管老化2010

    • Author(s)
      樂木宏実
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] VALISH studyから2010

    • Author(s)
      樂木宏実
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] Optimal Target Blood Pressure for Elderly Hypertensive Patients2010

    • Author(s)
      樂木宏実
    • Organizer
      The 23^<rd> scientific meeting of the International Society of Hypertension (ISH2010)
    • Place of Presentation
      バンクーバー(カナダ)(招待講演)
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 老年医学の新しい展望2010

    • Author(s)
      樂木宏実
    • Organizer
      第21回老年医学会北陸地方会
    • Place of Presentation
      福井
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] Functional Analysis of Apop Gene in the Viability of Cardiomyocytes.2010

    • Author(s)
      安田修, 樂木宏実
    • Organizer
      第14回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      奈良県新公会堂、奈良
    • Year and Date
      2010-04-01
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Presentation] 高血圧と血管老化2010

    • Author(s)
      樂木宏実
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 高齢者高血圧の治療指針2010

    • Author(s)
      樂木宏実
    • Organizer
      第52回日本老年医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-24
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 糖尿病患者の高血圧治療と糖尿病発症予防の高血圧治療2010

    • Author(s)
      樂木宏実
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山(招待講演)
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] VALISHからのレッスン2010

    • Author(s)
      樂木宏実
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] VALISH study から2010

    • Author(s)
      樂木宏実
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 老年医学の新しい展望2010

    • Author(s)
      樂木宏実
    • Organizer
      第21回老年医学会北陸地方会
    • Place of Presentation
      福井(招待講演)
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] ガイドライン改訂の課題2010

    • Author(s)
      樂木宏実
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] Optimal Target Blood Pressure for Elderly Hypertensive Patients2010

    • Author(s)
      Rakugi H
    • Organizer
      The 23rd scientific meeting of the International Society of Hypertension
    • Place of Presentation
      Vancouver
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 動脈硬化血管の遺伝子発現解析2010

    • Author(s)
      安田修、樂木宏実
    • Organizer
      第52回日本老年医学会学術集会・総会
    • Place of Presentation
      神戸国際会議場、神戸
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Presentation] ガイドライン改訂の課題2010

    • Author(s)
      樂木宏実
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 高齢者高血圧の治療指針2010

    • Author(s)
      樂木宏実
    • Organizer
      第52回日本老年医学会学術集会
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2010-06-24
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] Impairedmemory function in Timp-3 deficient mice.2009

    • Author(s)
      Yasuda O, Fukuo K, Rakugi H.
    • Organizer
      Japan Society of Gene Therapy The 15th Annual Meeting 2009.
    • Place of Presentation
      Osaka University Convention Center, Osaka
    • Year and Date
      2009-07-10
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Presentation] Treatment of very elderly patients with arrhythmia : from the point of geriatric medicine2009

    • Author(s)
      樂木宏実
    • Organizer
      The 73rd Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      大阪
    • Year and Date
      2009-03-20
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] New Japanese evidence of hypertension : -lessons from CASE-J & HIJ-CREATE-2009

    • Author(s)
      樂木宏実
    • Organizer
      17th A sian Pacific Congress of Cardiolog
    • Place of Presentation
      京都
    • Year and Date
      2009-05-21
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] ガイドラインが目指す厳格な降圧とその対策2009

    • Author(s)
      樂木宏実
    • Organizer
      第94回日本循環器学会九州・四国合同地方会ランチョンセミナー
    • Place of Presentation
      高知
    • Year and Date
      2009-06-26
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] 細胞外基質代謝による認知機能低下機構の解析2009

    • Author(s)
      安田修、樂木宏実
    • Organizer
      第51回日本老年医学会学術集会・総会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Presentation] Cardiovascular continuumにおけるβ遮断薬の役割 : 高血圧の立場から2009

    • Author(s)
      樂木宏実
    • Organizer
      第57回日本心臓病学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2009-09-20
    • Data Source
      KAKENHI-PROJECT-21390222
  • [Presentation] inhibition of apop gene prevents death of cells in culture following hypoxia/reoxigenation.2008

    • Author(s)
      Yasuda O, Fukuo K, Rakugi H.
    • Organizer
      The 72nd Annual Scientific Meeting of the Japanese Circulation Society.
    • Place of Presentation
      Fukuoka International Congress Center , Fukuoka
    • Year and Date
      2008-03-29
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Presentation] Apop gene is involved in hypoxia/reoxigenation induced cell death.2008

    • Author(s)
      Yasuda O, Fukuo K, Rakugi H.
    • Organizer
      22nd International Society of Hypertension.
    • Place of Presentation
      Internationales Congress Centrum Berlin, Berlin, Germany
    • Year and Date
      2008-06-19
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Presentation] Timp-3欠損マウスの認知機能解析2008

    • Author(s)
      安田修、樂木宏実
    • Organizer
      第50回日本老年医学会学術集会・総会
    • Place of Presentation
      幕張メッセ国際会議場、千葉
    • Year and Date
      2008-06-21
    • Data Source
      KAKENHI-PROJECT-20590882
  • [Presentation] 地域高齢者における認知機能とアルブミン/グロブリン比との関連( SONIC研究)

    • Author(s)
      小黒 亮輔,神出 計,中間 千香子,龍野洋慶,樺山 舞,稲垣 宏樹,増井 幸恵,池邉 一典,権藤 恭之,樂木 宏実
    • Organizer
      第56回日本老年医学会
    • Place of Presentation
      福岡国際会議場( 福岡県福岡市)
    • Year and Date
      2014-06-12 – 2014-06-14
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 閉塞性睡眠時無呼吸を有する高齢者における筋力・身体能力と閉塞性睡眠時無呼吸の重症度の関連性についての検討

    • Author(s)
      (a)伊東範尚(b)安延由紀子、武田昌生、小黒亮輔、前川佳敬、鷹見洋一、竹屋泰、山本浩一、杉本研、樂木宏実
    • Organizer
      第56回日本老年医学会学術集会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Data Source
      KAKENHI-PROJECT-24590882
  • [Presentation] Apoptogenic Protein is a Novel Phenotypic Marker of the Contractile Vascular Smooth Muscle Cells

    • Author(s)
      Osamu Yasuda, Hirofumi Soejima, Keishi Miyata, Hisayo Yasuda, Hiromi Rakugi, Yuichi Oike, Shoukei-Kim Mitsuyama, Hisao Ogawa
    • Organizer
      American Heart Association
    • Place of Presentation
      Chicago
    • Year and Date
      2014-11-17 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-26461364
  • [Presentation] 生活習慣病と認知機能障害との関連性-SONIC研究-

    • Author(s)
      龍野洋慶,神出 計,権藤恭之,小黒亮輔,中間千香子,樺山 舞,竹屋 泰,山本浩一,杉本 研,池邉一典,荒井康通,増井幸恵,高橋龍太郎,楽木宏実
    • Organizer
      第50回日本循環器病予防学会学術集会
    • Place of Presentation
      京都市勧業館 みやこめっせ( 京都府京都市)
    • Year and Date
      2014-07-20 – 2014-07-21
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] 閉塞性睡眠時無呼吸患者の無呼吸低呼吸評価法とbaPWVの関係

    • Author(s)
      (a)伊東範尚(b)武田昌生、小黒亮輔、前川佳敬、鷹見洋一、竹屋泰、山本浩一、杉本研、樂木宏実
    • Organizer
      第14回臨床血圧脈波研究会
    • Place of Presentation
      品川インターシティホール(東京都)
    • Data Source
      KAKENHI-PROJECT-24590882
  • [Presentation] 高齢者における降圧コントロール別にみた認知機能障害との関連( SONIC研究)

    • Author(s)
      龍野洋慶,神出 計,権藤恭之,小黒亮輔,中間千香子,樺山 舞,池邉一典,新井康通,増井幸恵,樂木宏実
    • Organizer
      第56回日本老年医学会
    • Place of Presentation
      福岡国際会議場( 福岡県福岡市)
    • Year and Date
      2014-06-12 – 2014-06-14
    • Data Source
      KAKENHI-PROJECT-25253059
  • [Presentation] Cognitive Function is associated with Serum Albumin/Globulin ratio in Japanese Elderly (SONIC study).

    • Author(s)
      Ryosuke Oguro,Kei Kamide, Chikako Nakama, Hirochika Ryuno, Mai Kabayama, Hiroki Inagaki, Yukie Masui, Kazunori Ikebe, Yasuyuki Gondo, Hiromi Rakugi
    • Organizer
      The 10th Congress of the European Union Geriatric Medicine Society
    • Place of Presentation
      Rotterdam (Netherlands)
    • Year and Date
      2014-09-17 – 2014-09-19
    • Data Source
      KAKENHI-PROJECT-25253059
  • 1.  NAKAGAMI Hironori (20325369)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 19 results
  • 2.  YAMAMOTO Koichi (00528424)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 42 results
  • 3.  SUGIMOTO Ken (20437403)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 31 results
  • 4.  OHISHI Mitsuru (50335345)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 41 results
  • 5.  OGIHARA Toshio (60107042)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 5 results
  • 6.  HIGAKI Jitsuo (70189744)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 7.  KATSUYA Tomohiro (30311757)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 12 results
  • 8.  KAMIDE Kei (80393239)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 44 results
  • 9.  FUKUO Keisuke (40156758)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 12 results
  • 10.  MORIGUCHI Atsushi (10273666)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  YASUDA Osamu (00372615)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 35 results
  • 12.  MIKI Tetsuro (00174003)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 13.  SATO Naoyuki (70372612)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  MORISHITA Ryuichi (40291439)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 15.  Takami Yoichi (90621756)
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  • 16.  MIKAMI Hiroshi (80173996)
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  • 18.  ISHIKAWA Kazuhiko (60379245)
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  • 19.  ITO Norihisa (00621757)
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  • 20.  GONDO Yasuyuki (40250196)
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  • 21.  IKEBE Kazunori (70273696)
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  • 22.  KARIO Kazuomi (60285773)
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  • 23.  高橋 利匡 (60807270)
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  • 24.  赤坂 憲 (70468081)
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  • 28.  Imai Yutaka (40133946)
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  • 29.  TABARA Yasuharu (00268749)
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  • 30.  OHKUBO Takayoshi (60344652)
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  • 31.  NODE Koichi (80359950)
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  • 32.  KAWANO Yuhei (90118076)
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  • 33.  MIURA Katsuyuki (90257452)
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  • 56.  池上 博司 (20221062)
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  • 65.  林 宏樹 (20813364)
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  • 66.  RYUNO Hirochika
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  • 67.  Staessen Jan A.
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  • 68.  NAKAGAWA Takeshi
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  • 69.  FUJITA Yoshiko
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  • 71.  HIROMINE Yoshihisa
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  • 72.  FUJINO Hidemi
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  • 73.  淺山 敬
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  • 74.  池邊 一典
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  • 75.  稲垣 宏樹
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  • 78.  小原 拓
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  • 79.  田中 稔
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  • 81.  加藤 和人
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  • 82.  小原 克彦
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  • 83.  市原 学
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  • 84.  長谷部 直幸
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  • 85.  宮田 敬士
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    # of Collaborated Products: 1 results
  • 86.  尾池 雄一
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    # of Collaborated Products: 1 results
  • 87.  郡山 弘
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    # of Collaborated Products: 1 results

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