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MASAKI Tomoo
眞崎 知生
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Alternative Names
MASAKI Tomoh 眞崎 知生
眞崎 智生 マサキ トモオ
真崎 知生 マサキ トモオ
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Researcher Number
60009991
Affiliation (based on the past Project Information)
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2007 – 2009: 東京女子医科大学, 国際統合医科学インスティテュート, 教授
2007: Tokyo Women's Medical University, 付置研究所, 特任教授
2006: 東京女子医科大学, 附属研究所, 特任顧問
1999: 国立循環器病センター, 研究所, 研究所長
1999: 国立循環器病センター研究所, バイオサイエンス部, 所長
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1997 – 1999: 国立循環器病センター研究所, 所長
1995 – 1996: Faculty of Medicine, Kyoto University Professor, 医学研究科, 教授
1991 – 1994: Kyoto University Pharmacology Professor, 医学部, 教授
1985 – 1991: 筑波大学, 基礎医学系, 教授
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Review Section/Research Field
Principal Investigator
General pharmacology
/
General medical chemistry
/
Neurophysiology and muscle physiology
/
Biological Sciences
Except Principal Investigator
General pharmacology
/
分子遺伝学・分子生理学
/
医学一般
/
Human pathology
/
動物発生・生理学
/
General pharmacology
/
Neurology
Keywords
Principal Investigator
エンドセリン / エンドセリン受容体 / 内皮細胞 / エンドセリン変換酵素 / EDRF / 一酸化窒素 / endothelin / endothelin receptor / Endothelin / 血管内皮
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More
/ 血管収縮 / エンドセリン受容体拮抗薬 / 国際薬理学連合受容体委員会 / 国際エンドセリン会議 / Endothelium / 過分極因子 / 平滑筋細胞 / 血管攣縮 / 動脈硬化 / ANP / 血管収縮弛緩 / 血圧 / 非選択的カチオンチャネル / カルシュウムチャンネル / vasoconstriction / endothelin converting enzyme / ジストログリカン / エンドセリン(ET) / アイソフォーム / bigET / 変換酵素 / ホスホラミドン / ET受容体 / 内皮細胞腫瘍 / 脳血管攣縮 / big ET / Endotheliumーderived relaxing factor / Smooth muscle / Autonomic nervous system / 酸素ラジカル / プロスタノイド / カルシュウムイオン / サブスタンスP / カルシウムイオン / 平滑筋 / 内皮由来生理活性物質 / 血管病変 / 増殖因子 / 収縮弛緩 / 血管生物学 / 動脈変化 / カルシウムチャネル / G蛋白質 / カルシウム / カルシウムインフラックス / メフェナム酸 / カルシウム拮抗薬 / 金属プロテアーゼ / ビッグエンドセリン / 平滑筋ミオシン / 平滑筋ミオシン重鎖遺伝子 / モノクロナール抗体 / α-アクチニン / 幼若平滑筋ミオシン / 小腸刷子緑ミオシン / 平滑筋ミオシン軽鎖遺伝子 / 筋発生 / 筋分化 / 筋フィラメント形成 / 筋蛋白質合成 / 収縮構造 / 細胞内遊離カルシュウム / ホスホリパ-ゼのリン酸化 / 平滑筋収縮機構 / 平滑筋収縮 / エンドセリンのcDNA / エンドセリンのアイソペプチド / エンドセリンのmRNA / intracellular free calcium ion / 血管拡張 / 血圧調節 / Blood pressure / Vasodilation / Vasoconstriction / 薬物受容体 / 受容体拮抗薬 / international receptor committee / conference on endothelin / endothelin antagonist / 細胞増殖 / 酸化LDL / 変性LDL受容体 / アルギニン輸送体 / 受容体輸送活性相関 / 変成LDL受容体 / 電位依存性カルシウムチャネル / 非選択的陽イオンチャネル / カチオンチャネル / vascular endothelium / nitric oxide / oxidized LDL / cell growth, dystroglycan / endothelin receptor antagonist / Receptor Nomenclature and Drug Classification Committee / International Union of Pharmacological Sciences / International Conference on Endothelin / エンドセリ / Endothelin receptor / IUPHA / Endothelin antagonist / ラミニン / 血管新生 / インテグリン / ファイブロネクチン / 細胞骨格 / ファイブロネクチ / 血管内皮細胞 / Laminin / Fibronectin / Endothelial cell / Dystroglycan / Integrin / Neovascularization / Cytoskeleton
…
More
Except Principal Investigator
LOX-1 / 内皮細胞 / 酸化LDL / 動脈硬化 / カルシウムチャンネル / クローニング / レクチン様酸化LDL受容体 / 血小板 / 平滑筋 / caged-ATP / コネクチン / αーアクチニン / 筋肉 / 酸化LDL受容体 / 血管内皮細胞 / oxidized LDL / endothelial cells / D4S10 / D4S43 / 微小循環 / 物質代謝 / 局所血流 / 分子生物学 / 医工学 / テトラヒドロビオプテリン / ドーパミン遊離 / 細胞内遊離カルシウム濃度 / パッチクランプ / 結合実験 / ビオプテリン / 結合蛋白質 / 一酸化窒素合成酵素 / 分子病理 / がん / 膵臓 / 膵臓がん / MAPK / RNA干渉 / 分子診療 / アポトーシス / 増殖抑制 / 細胞回転 / 網羅的解析 / 膵臓癌 / アクチン結合タンパク / 調節蛋白の分布 / ミオシン軽鎖キナーゼ / 重合の周期構造 / 滑り速度 / 調節タンパクの交叉実験 / cagedーATP / 構造の不均一性 / 筋の収縮弛緩 / コフィリン / ゲルゾリン / アクトミオシン / アクチン フィラメント / actin binding proteins / gizzard muscle / regulatory proteins / MLCK / connectin / structural repeat / sliding velocity / 筋分化 / 骨格筋細胞 / 中胚葉誘導 / MyoD / 転写制御 / 筋原線維形成 / 筋蛋白質 / 細胞系譜 / 筋原線継形成 / 筋原繊維形成 / 細胞分化 / 筋分化因子 / MyoDファミリ- / 収縮蛋白質 / 遺伝子制御 / Muscle differentiation / Skeletal muscle cell / Mesoderm induction / MyoD family / Cell lineage / Myofibrillogenesis / Muscle proteins / Regulation of transcription / トランスジェニックマウス / ノックアウトマウス / 炎症 / LOX-1リガンド / oxidized LDL receptor / transgenic mouse / エンドセリン / 血管平滑筋 / 非選択的陽イオンチャンネル / ストア作動性Ca^<2+>チャンネル / SK＆F96365 / LOE908 / trp / ストア作動性カルシウムチャンネル / カルシウム / endothelin-1 / vascular smooth muscle cell / nonselective cation channels / store-operated Ca^<2+> channel / SK＆F 96365 / LOE 908 / transient receptor potential / 血栓 / 内膜増殖 / atherosclerosis / thrombosis / intimal hyperplasia / 筋収縮 / Ca調節蛋白質 / 細胞骨格蛋白質 / 骨格筋 / トロポニン / トロポミオシン / α-アクチニン / Muscle / Muscle contraction / Calcium regulatory proteins / Cytoskeletal proteins / Skeletal muscle / ハンチントン病 / 第4染色体 / 遺伝子連鎖 / DNAプロ-ブ / 線条体mRNA / DNAマーカー / S4S43 / Huntington's disease / 4th chromosome / linkage analysis / DNA probes / striatal mRNA
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Research Projects
(
29
results)
Co-Researchers
(
73
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Identification of molecular targets for human pancreatic cancer
Principal Investigator
FURUKAWA Toru
Project Period (FY)
2007 – 2009
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Human pathology
Research Institution
Tokyo Women's Medical University
Clarification of the mechanisms of cardiovascular dysfunction and the resultant organ failure
Principal Investigator
SAWAMURA Tatsuya
Project Period (FY)
2006 – 2007
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
General pharmacology
Research Institution
National Cardiovascular Center Research Institute
レクチン様酸化LDL受容体の機能と病態生理的役割
Principal Investigator
沢村 達也
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
National Cardiovascular Center Research Institute
Regulation of endothelial cell behavior by dystroglycan in neovascularization
Principal Investigator
Principal Investigator
KANOH Yumiko
, 眞崎 知生
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
General pharmacology
Research Institution
National Cardiovascular Center Research Institute
Investigations for developing novel diagnostic methods, therapeutics, and drugs utilizing lectin-like oxidized LDL receptor-1 (LOX-1)
Principal Investigator
SAWAMURA Tatsuya
Project Period (FY)
1999 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
General pharmacology
Research Institution
National Cardiovascular Center Research Institute
The structure and function of Ca^<2+>-permeable nonselective cation channels
Principal Investigator
MIWA Soichi
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General pharmacology
Research Institution
Hokkaido University
Kyoto University
Pharmacology
Principal Investigator
Principal Investigator
MASAKI Tomoh
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for international Scientific Research
Research Field
General pharmacology
Research Institution
National Cardiovascular Center Research Institute
Pharmacology of endothelin and endothelin receptor
Principal Investigator
Principal Investigator
MASAKI Tomoh
Project Period (FY)
1996
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
KYOTO UNIVERSITY
Study on the regulatory mechanisms of endothelium-dependent vasoconstriction and growth of vascular cells
Principal Investigator
Principal Investigator
MASAKI Tomoh
Project Period (FY)
1995 – 1998
Research Category
Grant-in-Aid for Specially Promoted Research
Review Section
Biological Sciences
Research Institution
National Cardiovascular Center Research Institute
Kyoto University
血管系の機能および病変の基盤としての内皮平滑筋連関
Principal Investigator
Principal Investigator
眞崎 知生
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
新しい循環調節薬としてのエンドセリン変換酵素抑制薬開発のための研究
Principal Investigator
Principal Investigator
真崎 知生, 眞崎 知生
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
General pharmacology
Research Institution
Kyoto University
バイオプテリン結合活性をもつ新しい機能蛋白質群のcDNAクローニング
Principal Investigator
三輪 聡一
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto University
Pharmacology of endothelin receptor and its agonist/antagonist
Principal Investigator
Principal Investigator
MISAKI Tomoh, 真崎 知生
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
KYOTO UNIVERSITY
内皮細胞由来血管収縮弛緩物質の産生分泌とそれによる平滑筋の応答、血管攣縮の機構
Principal Investigator
Principal Investigator
眞崎 知生
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
エンドセリン誘発収縮に関与する新しい因子の検索とそのクローニング
Principal Investigator
Principal Investigator
真崎 知生, 眞崎 知生
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
General medical chemistry
Research Institution
Kyoto University
テトラヒドロビオプテリン受容体のクローニング及びその機能解析
Principal Investigator
三輪 聡一
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto University
内皮細胞由来血管収縮弛緩物質の産生分泌とそれによる平滑筋の応答、血管攣縮の機構
Principal Investigator
Principal Investigator
眞崎 知生
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
血管系の機能および病変の基盤としての内皮平滑筋連関
Principal Investigator
Principal Investigator
眞崎 知生
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
Molecular mechanisms of myogenesis
Principal Investigator
OBINATA Takashi
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
動物発生・生理学
Research Institution
Chiba University
エンドセリンの薬理学的研究
Principal Investigator
Principal Investigator
真崎 知生, 眞崎 智生 (眞崎 知生)
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
University of Tsukuba
Kyoto University
血管系の機能および病変の基盤としての内皮平滑筋連関
Principal Investigator
Principal Investigator
真崎 知生
Project Period (FY)
1990
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Institution
University of Tsukuba
Analysis of effect of endothelin on blood pressure and its physiological meanings
Principal Investigator
Principal Investigator
MASAKI Tomoh
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
General pharmacology
Research Institution
KYOTO UNIVERSITY
University of Tsukuba
Regulation Mechanisms of Cotraction-Relaxation of Muscle
Principal Investigator
MIHASHI Koshin
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
分子遺伝学・分子生理学
Research Institution
Nagoya University
臓器微小循環と物質代謝及びその障害に関する分子生物学的・医工学的研究
Principal Investigator
神谷 瞭
Project Period (FY)
1989
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
医学一般
Research Institution
Hokkaido University
Pharmacological and biological studies of an endothelium-derived vasoconstrictive peptide, endothelium.
Principal Investigator
Principal Investigator
MASAKI Tomoh
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
General pharmacology
Research Institution
Kyoto University
University of Tsukuba
筋分化における可塑性の分子生物学
Principal Investigator
Principal Investigator
眞崎 知生
Project Period (FY)
1988
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
Neurophysiology and muscle physiology
Research Institution
University of Tsukuba
New Strategies for Elucidation of a Gene Defect in Huntington's Disease
Principal Investigator
KANAZAWA Ichiro
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Neurology
Research Institution
University of Tsukuba
Regulatory mechanisms of structure and function of muscle
Principal Investigator
OHTSUKI Iwao
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
分子遺伝学・分子生理学
Research Institution
Kyushu University
細胞の構造変化の基礎をなす収縮蛋白質の多様な機能と形態
Principal Investigator
Principal Investigator
真崎 知生
Project Period (FY)
1985
Research Category
Grant-in-Aid for Special Project Research
Research Institution
University of Tsukuba
# of Projects (Dsc)
# of Projects (Asc)
1.
SAWAMURA Tatsuya
(30243033)
# of Collaborated Projects:
11 results
# of Collaborated Products:
0 results
2.
MAWA Soichi
(40157706)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
3.
NINOMIYA Haruaki
(80212124)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
4.
多田 道彦
(90093434)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
5.
OBINATA Yakashi
(40012413)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
6.
GOTO Katsutoshi
(30012660)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
7.
TAIRA Norio
(60004553)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
8.
江橋 節郎
(10009863)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
9.
VANHOUTTE P
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
10.
VANE J
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
11.
TODA Noboru
(50025590)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
井村 裕夫
(10025570)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
13.
山野 俊雄
(40028270)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
14.
OOTSUKI Iwao
(70009992)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
YANAGISAWA Masashi
(20202369)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
YAZAKI Yoshio
(20101090)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
NONOMURA Yoshiaki
(80009993)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
NABESHIMA Yoichi
(60108024)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
19.
SHIMADA Yutaka
(70009116)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
20.
YAMADA Kazuhiro
(20053027)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
21.
MARUYAMA Koscack
(60012267)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
22.
KANOH Yumiko
(30214498)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
23.
鈴木 光
(80037548)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
24.
藤原 元始
(90025536)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
25.
柳澤 輝行
(90133941)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
26.
越村 邦夫
(90192575)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
27.
岡本 安雄
(80293877)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
28.
FURUKAWA Toru
(30282122)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
TAKAGAKI Yohtaro
(50281324)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
YAMAMOTO Masakazu
(60220498)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
HATORI Takashi
(50208550)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
HIRATA Yasunobu
(70167609)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
MIHASHI Koshin
(30022594)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
SATO Noriyuki
(30025481)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
ASASHIMA Makoto
(00090564)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
FUKAO Mitsuhiro
(10250432)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
TAKAHASHI Koui
(40001432)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
KANAZAWA Ichiro
(30110498)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
神谷 瞭
(50014072)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
大橋 俊夫
(80020832)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
古川 俊之
(20101082)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
大島 宣雄
(50015971)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
43.
林 紘三郎
(90026196)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
44.
木村 定雄
(40134225)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
45.
多久和 陽
(60171592)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
46.
平田 結喜緒
(50135787)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
47.
村上 和雄
(70110517)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
48.
入沢 宏
(30033947)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
49.
北 徹
(60161460)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
50.
室田 誠逸
(50072989)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
51.
浜田 義雄
(10132739)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
52.
小沢 〓二郎
(20014178)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
53.
栗山 煕
(40037495)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
54.
山本 研二郎
(30046825)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
55.
比企 一晃
(30263099)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
56.
藤原 敬己
(10190092)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
57.
ANGGARD E.E.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
58.
LIPPTON H.L.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
59.
SNYDER S.H.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
60.
KON V.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
61.
REID J.J.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
62.
LUSCHER T.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
63.
MAGUN B.U.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
64.
HIGHSMITH R.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
65.
POLAK J.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
66.
DUNN M.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
67.
WARTON J.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
68.
SCOTTーBURDEN
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
69.
RYAN U.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
70.
DAVENPORT A.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
71.
SCOTT Burden
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
72.
WHARTON J.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
73.
VANE John
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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