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GOTO Katsutoshi  後藤 勝年

ORCIDConnect your ORCID iD *help
… Alternative Names

和藤 勝年  ゴトウ カツトシ

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Researcher Number 30012660
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2006: 筑波大学, 名誉教授
2004 – 2005: 筑波大学, 大学院・人間総合科学研究科, 教授
1990 – 2003: 筑波大学, 基礎医学系, 教授
2002: 筑波大, 基礎医学系, 教授
1997: 筑波大学, 臨床医学系, 教授
1987 – 1989: 筑波大学, 基礎医学系, 助教授
1986: 筑大, 基礎医学系, 助教授
Review Section/Research Field
Principal Investigator
General pharmacology / 応用薬理学・医療系薬学
Except Principal Investigator
Circulatory organs internal medicine / General pharmacology / General pharmacology / 血管生物学 / Biological Sciences / Bioproduction chemistry/Bioorganic chemistry / 応用薬理学・医療系薬学
Keywords
Principal Investigator
CGRP / エンドセリン / オレキシン / 摂食行動 / ナルコレプシー / 腸管膜動脈 / 知覚神経 / 冠血管 / mesenteric artery / SB209670 … More / エンドセリン受容体 / カプサイシン / HIF-1α / ox1受容体 / ox2受容体 / 覚醒 / OXI受容体 / OX2受容体 / 血管拡張神経 / 高血圧と加齢 / 微小循環系 / 骨格筋収縮 / 血流増加反応 / 骨格筋強縮 / 血管内皮細胞 / 心臓 / 骨格筋 / postーtetanic hyperemia / 座骨神経 / 求心性知覚神経 / CGRP拮抗薬 / 血中濃度 / 心筋 / 代謝性血流調筋 / vasodilation / hypertension / endothelium / heart / microcirculation / endothelin-1 / ET_B受容体 / アストロサイト / 凍結損傷 / 脊髄損傷 / アンタゴニスト / 中枢神経系 / 脳抽出液 / 増殖因子 / cold injury / Endothelin / ET_B receptor / Astrocytes / 局所血流 / ラット後肢 / 骨格筋運動 / CO2分圧 / カルシトニン遺伝子関連ペプチド / 二酸化炭素 / 血流 / 血管弛緩 / EDHF / ラット / regional blood flow / hindlimb / askeletal muscle / sensory nerve / CO2 / capsaicin / 慢性循環器疾患 / 心筋梗塞 / 慢性心不全 / リモデリング / ET受容体拮抗薬 / 心筋症ハムスター / 心不全 / 受容体 / 受容体拮抗薬 / アポトーシス / ミトコンドリア / 動脈硬化 / upregulation / 心筋梗塞ラット / 変換酵素 / 免疫組織化学 / endothelin / chronic circulatory disease / myocardial infarction / chronic heart failure / cardiac remodeling / cardiomyopathic hamster / ET receptor antagonist / 睡眠覚醒 / トランスジェニックマウス / ノックアウトマウス / スライスパッチクランプ / 神経回路 / 行動解析 / カルシウム感受性タンパク質 / カルシウム / イメージング / コレシストキニン / 破傷風毒素 / GFP / 免疫染色 / 睡眠 / セロトニン / アセチルコリン / パッチクランプ / 遺伝子改変マウス / 脳室内投与 / カタプレキシー / 抗体 / Orexin / Sleep and wakefulness / Feeding behavior / Transgenic mice / Knockout mice / Slice patch clamp / Neuronal network / Behavioral analysis / 非アドレナリン非コリン作動性神経 / カルシトニン遺伝子関連ペプチド(CGRP) / CGRP受容体 / アデニレートシクラーゼ / 心房筋 / 血管拡張神経内皮細胞 / サイクリックAMP / 冠動脈 / 脳底動脈 / 内皮細胞 / 非アドレナリン非コリン作動性(NANC)神経 / 陽性変時変力作用 / アデニルシクラーゼ / 神経ペプチド / Nonadrenergic noncholinergic nerve / CGRP (Calcitonin gene-related peptide) / CGRP-receptors / Adenylate cyclase / cardiac muscle / coronary artery … More
Except Principal Investigator
エンドセリン / 心不全 / endothelin / 薬理学 / 分子生物学 / エンドセリン拮抗薬 / 心肥大 / 神経ペプチド / 循環器疾患 / heart failure / endothelin antagonist / オレキシン / レプチン / orexin / 血圧 / 内皮細胞 / 血管収縮 / カルシュウムチャンネル / Endothelin / サイトカイン / 循環薬理学 / 病態生理学 / エンドセリン受容体遮断薬 / molecular biology / pharmacology / 分子薬理学 / molecular pharmacology / 遺伝子発現 / gene expression / グレリン / 摂食行動 / 覚醒 / 睡眠 / ナルコレプシー / leptin / feeding / narcolepsy / JAK2 / NPY / エンドセリン(ET) / アイソフォーム / bigET / 変換酵素 / ホスホラミドン / ET受容体 / 内皮細胞腫瘍 / 脳血管攣縮 / big ET / 血管内皮 / 平滑筋 / 内皮由来生理活性物質 / 血管病変 / 血管収縮弛緩 / 増殖因子 / 収縮弛緩 / 血管生物学 / 血管攣縮 / 動脈変化 / 平滑筋細胞 / 動脈硬化 / EDRF / ANP / 脳動脈 / 血管拡張神経 / 一酸化窒素 / 情動 / 扁桃体 / 分解条床核 / エンドセリン受容体 / 細胞内遊離カルシュウム / ホスホリパ-ゼのリン酸化 / 平滑筋収縮機構 / 平滑筋収縮 / エンドセリンのcDNA / エンドセリンのアイソペプチド / エンドセリンのmRNA / vasoconstriction / endothelin receptor / intracellular free calcium ion / 血管拡張 / 血圧調節 / Blood pressure / Vasodilation / Vasoconstriction / 脳血管 / 血管れん縮 / 免疫組織化学 / 脳脊髄液 / 血管内皮細胞 / 脳血管れん縮 / エンザイムイムノアッセイ / Cerebral vasospasm / Cerebral artery / Immunohistochemistry / Cerebrospinal fluid / Vascular endothelium / 新規生体機能調節ペプチド / ケモカイン / 好中球活性化因子 / 細胞生存活性因子 / 構造解析 / アミノ酸配列決定 / MALDI-TOF質量分析 / 気管平滑筋弛緩因子 / アミノ酸配列分析 / FAB質量分析 / Regulatory Peptide / Cytokine / Chemokine / Neurtrophil Activator / Survival Factor / Structure-Analysis / Amino Acid Sequence / Mass-Spectra / cardiac hypertrophy / cardiovascular pharmacology / pathophysiology / 肺高血圧 / エンドセリレ拮抗薬 / 新治療法 / cardiovascular diseases / pulmonary hypertension / グルホシネート / 中毒 / 昏睡 / けいれん / 呼吸停止 / 除草剤 / 農薬 / glofosinate / poisoning / coma / seizure / apnea / herbicide / agricultural chemical / エネルギー代謝異常 / 心筋保護 / 心血管作動性物質 / 不全心筋 / 心臓血管作動性物質 / 分子循環器病学 / 心筋細胞 / energy metabolism disturbance / cardioprotection / cardrovascular substances / failing heart / 拮抗薬 / 生理薬理学 / 細胞内情報伝達系 / 分子循環器学 / エネルギー代謝 / 病状悪化 / heart failare / antagonist / phtsiology / mclesular biology / cardiac hypeitrsphy / 肥満 / OX1受容体 / OX2受容体 / ghrelin / wakefulness / sleep / obesity / アセチルコリン / セロトニン / 適応行動 / グルコース / エネルギーバランス / arousal / acetylcholine / serotonin / adaptive behavior / 転写調節 / フェノフィプレート / エンドセリン遮断薬 / 運動耐容能 / トレッドミル / 心筋リモデリング / 高血圧 / PPAR-α / フェノフィブレート / AP-1 / 脂肪代謝 / cardiovascular disease / transcription / fenofibrate / endothelin blocker / 視床下部 / TNF-α / PI3K / PI3キナーゼ / K-ATPチャンネル / JAK2キナーゼ / STAT-3 / hypothalamus / TNF-alfa Less
  • Research Projects

    (25 results)
  • Research Products

    (40 results)
  • Co-Researchers

    (58 People)
  •  扁桃体機能、情動の制御に関わる新規神経ペプチドの検索とその生理作用の解明

    • Principal Investigator
      桜井 武
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Mechanisms and physiological roles of regulation of orexin-producing neurons by leptin and TNF-alfa

    • Principal Investigator
      SAKURAI Takeshi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  Molecular pharmacological study and development of new treatment by investigating endothelin in cardiovascular diseases.

    • Principal Investigator
      MIYAUCHI Takashi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  The analysis of the mechanisms of sleep/wakefulness and feeding behavior regulated by orexinPrincipal Investigator

    • Principal Investigator
      GOTO Katsutoshi
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  Study of the mechanisms that regulate the activity of orexin-producing neuron.

    • Principal Investigator
      SAKURAI Takeshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  摂食行動に関与する新規神経ペプチド、オレキシンの生理作用に関する研究Principal Investigator

    • Principal Investigator
      後藤 勝年
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  Molecntan biological and pharmaco-physiological approach to pathophysiological roles of endothelin-1 in aggrarating heart failure

    • Principal Investigator
      MIYAUCHI Takashi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tsukuba
  •  Molecular and Developmental Biological Research on Roles of a novel neuropeptide, Orexin

    • Principal Investigator
      SAKURAI Takeshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  Exploration of the novel therapeutic methods for the treatment of chronic circulatory diseasesPrincipal Investigator

    • Principal Investigator
      GOTO Katsutoshi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      University of Tsukuba
  •  Molecular pharmacological approach to roles of endothelin in heart failure and deverlopmet of new tehrapeuetin strategy

    • Principal Investigator
      MIYAUCHI Takashi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tsukuba
  •  エンドセリン拮抗薬を用いた心不全に対する新治療法の開発のための分子薬理学的研究

    • Principal Investigator
      MIYAUCHI Takashi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tsukuba
  •  The Relationship between Serum Glufosinate Concentration and Severity of Poisoning Caused by the Ingestion of a Herbicide Containing Glufosin

    • Principal Investigator
      KOYAMA Kanji
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      University of Tsukuba
  •  The role new pepdidergic neuron in autoregulation of regional blood flow.Principal Investigator

    • Principal Investigator
      GOTO Katsutoshi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  Biochemical Study on Novel Bioregulatory Peptides

    • Principal Investigator
      GOTO Katsutoshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      University of Tsukuba
  •  The study of pathophysiological roles of endothelin in heart failure and cardiac hypertrophy and the development of a new treatment based on these findings

    • Principal Investigator
      SUGISHITA Yasuro
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tsukuba
  •  Basic research for the development of the new treatment using endothelin receptor antagonists in cardiovascular diseases

    • Principal Investigator
      SUGISHITA Yasuro
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tsukuba
  •  Analysis of dedifferentiation and growth of glial cells in tissue regeneration process after brain damagePrincipal Investigator

    • Principal Investigator
      GOTO Katsutoshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      University of Tsukuba
  •  血管系の機能および病変の基盤としての内皮平滑筋連関

    • Principal Investigator
      眞崎 知生
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  脳血管収縮の神経および内皮細胞による調節

    • Principal Investigator
      SAITO Akira
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      血管生物学
    • Research Institution
      University of Tsukuba
  •  Regulation of cardiovascular function by novel peptidergic vasodilator nervesPrincipal Investigator

    • Principal Investigator
      GOTO Katsutoshi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  Endothelium-derived vasoactive peptide and cerebral vasospasm

    • Principal Investigator
      SAITO Akira
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba
  •  エンドセリンの薬理学的研究

    • Principal Investigator
      真崎 知生, MASAKI Tomoh (眞崎 知生)
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of Tsukuba
      Kyoto University
  •  Analysis of effect of endothelin on blood pressure and its physiological meanings

    • Principal Investigator
      MASAKI Tomoh
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      KYOTO UNIVERSITY
      University of Tsukuba
  •  Pharmacological and biological studies of an endothelium-derived vasoconstrictive peptide, endothelium.

    • Principal Investigator
      MASAKI Tomoh
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University
      University of Tsukuba
  •  The control by peripheral nerves of the function and drug senaitivity of the cadiac muscle and coronary blood vessel.Principal Investigator

    • Principal Investigator
      GOTO Katsutoshi
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      University of Tsukuba

All 2006 2005 2004 2003 2002 2001 Other

All Journal Article

  • [Journal Article] Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner.2006

    • Author(s)
      Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T
    • Journal Title

      J Neurophysiol. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005

    • Author(s)
      Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M
    • Journal Title

      Neuron 46(2)

      Pages: 297-308

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Cholecystokinin Activates Orexin/Hypocretin Neurons through the Cholecystokinin A Receptor.2005

    • Author(s)
      Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T
    • Journal Title

      J Neurosci. 25(32)

      Pages: 7459-69

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005

    • Author(s)
      Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M.
    • Journal Title

      Neuron. 46(2)

      Pages: 297-308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005

    • Author(s)
      Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M.
    • Journal Title

      Neuron 46(2)

      Pages: 297-308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005

    • Author(s)
      Sakurai T, Nagata R, Yamanaka A, Kawamura H.Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M
    • Journal Title

      Neuron. 46(2)

      Pages: 297-308

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.2005

    • Author(s)
      Sakurai T, Yamanaka A, Goto K, et al.
    • Journal Title

      Neuron 46(2)

      Pages: 297-308

    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Cholecystokinin Activates Orexin/Hypocretin Neurons through the Cholecystokinin A Receptor.2005

    • Author(s)
      Tsujino N, Yamanaka A, Goto K, Sakurai T, et al.
    • Journal Title

      J Neurosci. 25(32)

      Pages: 7459-7469

    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Cholecystokinin Activates Orexin/Hypocretin Neurons through the Cholecystokinin A Receptor.2005

    • Author(s)
      Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T.
    • Journal Title

      J Neurosci. 25(32)

      Pages: 7459-7469

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Emergence of clinical applications of endothelin system inhibitors.2004

    • Author(s)
      Goto K, Miyauchi T, et al.
    • Journal Title

      Journal of Cardiovascular Pharmacololgy 44

      Pages: 13-14

    • Data Source
      KAKENHI-PROJECT-15390077
  • [Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.2004

    • Author(s)
      Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T
    • Journal Title

      J Neurosci. 24(32)

      Pages: 7159-66

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.2004

    • Author(s)
      Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T.
    • Journal Title

      J Neurosci. 24(32)

      Pages: 7159-7166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.2004

    • Author(s)
      Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T.
    • Journal Title

      J.Neurosci. 24(32)

      Pages: 7159-7166

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.2004

    • Author(s)
      Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T.
    • Journal Title

      J Neurosci. 24(32)

      Pages: 7159-7166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Chronic administration of an endothelin-A receptor antagonist improves exercise capacity in rats with myocardial infarction-induced congestive heart failure2004

    • Author(s)
      Miyauchi T, Fujimori A, Maeda S, Iemitsu M, Sakai S, Shikama H, Tanabe T, Matsuda M, Goto K, Yamaguchi I.
    • Journal Title

      Journal of Cardiovascular Pharmacology 44

      Pages: 64-67

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390077
  • [Journal Article] Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisomeproliferator-activated receptor-α partly via blockade of c-Jun NH2-terminal kinase pathway2004

    • Author(s)
      Irukayama-Tomobe Y, Miyauchi T, Sakai S, Kasuya Y, Ogata T, Takanashi M, Iemitsu M, Sudo T, Goto K, Yamaguchi I.
    • Journal Title

      Circulation 109

      Pages: 904-910

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390077
  • [Journal Article] Establishment of hypoxia inducible factor-1α overexpressing cells that produce endothelin-12004

    • Author(s)
      Takanashi M, Miyauchi T, Kakinuma Y, Goto K, Yamaguchi I.
    • Journal Title

      Journal of Cardiovascular Pharmacology 44

      Pages: 168-273

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390077
  • [Journal Article] Serotonergic regulation of the orexin/hypocretin neurons through the 5-HTIA receptor.2004

    • Author(s)
      Muraki Y, Yamanaka A, Goto K. et al.
    • Journal Title

      J.Neurosci. 24(32)

      Pages: 7159-7166

    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Hypothalamic orexin neurons regulate arousal according to energy balance in mice.2003

    • Author(s)
      Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami K, Sugiyama F, Goto K, Yanagisawa M, Sakurai T
    • Journal Title

      Neuron 38(5)

      Pages: 701-13

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Regulation of orexin neurons by the monoaminergic and cholinergic systems.2003

    • Author(s)
      Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T.
    • Journal Title

      Biochem Biophys Res Commun 303(1)

      Pages: 120-129

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Hypothalamic Orexin neurons regulate arousal according to energy balance in mice.2003

    • Author(s)
      Yamanaka A., Beuckmann CT., Willie JT., Hara J., Tsujino N., Mieda M., Tominaga M., Yagami K., Sugiyama F., Goto K., Yanagisawa M., Sakurai T.
    • Journal Title

      Neuron. 38

      Pages: 701-713

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Orexin receptor type-1 couples exclusively to pertussis toxin insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins2003

    • Author(s)
      Zhu Y., Miwa Y., Yamanaka A., Yada T., Shibahara M., Abe Y., Sakurai T., Goto K.
    • Journal Title

      J.Pharmacol.Sci. 92

      Pages: 259-266

    • NAID

      10011209728

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Orexin receptor type-1 couples exclusively to pertussis toxin insensitive G-proteins, while orexin receptor type-2 couples t both pertussis toxin-sensitive and -insensitive G-proteins2003

    • Author(s)
      Zhu Y., Miwa Y., Yamanaka A., Yada T., Shibahara M., Abe Y., Sakurai T., Goto K.
    • Journal Title

      J.Pharmacol.Sci. 92

      Pages: 259-266

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Hypothalamic orexin neurons regulate arousal according to energy balance in mice.2003

    • Author(s)
      Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami K, Sugiyama F, Goto K, Yanagisawa M, Sakurai T.
    • Journal Title

      Neuron 38(5)

      Pages: 701-713

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Regulation of orexin neurons by the monoaminergic and cholinergic systems.2003

    • Author(s)
      Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T
    • Journal Title

      Biochem Biophys Res Commun. 303(1)

      Pages: 120-9

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Regulation of orexin neurons by the monoaminergic and cholinergic systems.2003

    • Author(s)
      Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T.
    • Journal Title

      Biochem.Biophys.Res.Commun. 303(1)

      Pages: 120-129

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive nathwavs.2002

    • Author(s)
      Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T.
    • Journal Title

      Physiol Behav 77(2-3)

      Pages: 251-257

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] The human prepro-orexin gene regulatory region that activates gene expression in the lateral region and represses it in the medial regions of the hypothalamus.2002

    • Author(s)
      Moriguchi T, Sakurai T, Takahashi S, Goto K, Yamamoto M
    • Journal Title

      J Biol Chem. 277(19)

      Pages: 16985-92

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Related Articles, The human prepro-orexin gene regulatory region that activates gene expression in the lateral region and represses it in the medial regions of the hypothalamus.2002

    • Author(s)
      Moriguchi T, Sakurai T, Takahashi S, Goto K, Yamamoto M.
    • Journal Title

      J Biol Chem. 277(19)

      Pages: 16985-16992

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Vascular endothelin-B receptor system in vivo plays a favorable inhibitory role in vascular remodeling after injury revealed by endothelin-B receptor-knockout mice.2002

    • Author(s)
      Murakoshi N, Miyauchi T, Kakinuma Y, Ohuchi T, Goto K, Yanagisawa M, Yamaguchi I
    • Journal Title

      Circulation 106(15)

      Pages: 1991-1998

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470147
  • [Journal Article] Orexins activate histaminergic neurons via the orexin 2 receptor.2002

    • Author(s)
      Yamanaka A, Tsujino N, Funahashi H, Honda K, Guan JL, Wang QP, Tominaga M, Goto K, Shioda S, Sakurai T
    • Journal Title

      Biochem Biophys Res Commun. 290(4)

      Pages: 1237-45

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Involvement of endogenous endothelin-1 in exercise-induced redistribution of tissue blood flow An endothelin receptor antagonist reduces the redistribution.2002

    • Author(s)
      Maeda S, Miyauchi T, Iemitsu M, Tanabe T, Irukayama-Tomobe Y, Goto K, Yamaguchi I, Matsuda M
    • Journal Title

      Circulation 106(17)

      Pages: 2188-2193

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470147
  • [Journal Article] Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways.2002

    • Author(s)
      Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T.
    • Journal Title

      Physiol.Behav. 77(2-3)

      Pages: 251-257

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370029
  • [Journal Article] Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways.2002

    • Author(s)
      Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T.
    • Journal Title

      Physiol Behav. 77(2-3)

      Pages: 251-257

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways.2002

    • Author(s)
      Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T
    • Journal Title

      Physiol Behav. 77(2-3)

      Pages: 251-7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Regulation of orexin neurons by the monoaminergic and cholinergic systems.2002

    • Author(s)
      Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T.
    • Journal Title

      Biochem Biophys Res Commun. 303(1)

      Pages: 120-129

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] A combination of oral endothelin-A receptor antagonist and oral prostacyclin analogue is superior to each drug alone in ameliorating pulmonary hypertension in rats2002

    • Author(s)
      Ueno M, Miyauchi T, Sakai S, Yamauchi-Kohno R, Goto K, Yamaguchi I
    • Journal Title

      Journal of the American College of Cardiology 40(1)

      Pages: 175-181

    • NAID

      10010226459

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470147
  • [Journal Article] Orexins activate histaminergic neurons via the orexin 2 receptor.2002

    • Author(s)
      Yamanaka A, Tsujino N, Funahashi H, Honda K, Guan JL, Wang QP, Tominaga M, Goto K, Shioda S, Sakurai T.
    • Journal Title

      Biochem Biophys Res Commun. 290(4)

      Pages: 1237-1245

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • [Journal Article] Novel molecular mechanism of increased myocardial endothelin-1 expression in the failing heart involving the transcriptional factor hypoxia-inducible factor-1α induced for impaired myocardial energy metabolism.2001

    • Author(s)
      Kakinuma Y, Miyauchi T, Yuki K, Murakoshi N, Goto K, Yamguchi I
    • Journal Title

      Circulation 103(19)

      Pages: 2387-2394

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470147
  • [Journal Article] Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner.

    • Author(s)
      Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T.
    • Journal Title

      J Neurophysiol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104009
  • 1.  SAKURAI Takeshi (60251055)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 31 results
  • 2.  KASUYA Yoshitoshi (70221877)
    # of Collaborated Projects: 7 results
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    # of Collaborated Products: 8 results
  • 4.  MASAKI Tomoh (60009991)
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  • 7.  YAMANAKA Akihiro (60323292)
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  • 8.  井村 裕夫 (10025570)
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  • 57.  WHARTON J.
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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