Takeuchi Atsuko 竹内敦子

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TAKEUCHI Atsuko 竹内敦子

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Researcher Number	00535239
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2022: 東北大学, 医学系研究科, 助教 2015: 東北大学, 医学(系)研究科(研究院), 助教 2012 – 2013: 東北大学, 医学(系)研究科(研究院), 助教 2009 – 2010: Tohoku University, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Neurology / Cerebral neurosurgery Except Principal Investigator Medium-sized Section 52:General internal medicine and related fields / Neurology
Keywords	Principal Investigator プリオン病 / プリオン / in vitro / クロイツフェルト・ヤコブ病 / クロイツフェルトヤコブ病 / PMCA法 / 試験管内増幅 / PMCA / in vitro増幅 / in vitro増幅法 … More / 致死性家族性不眠症 / 視床型クロイツフェルト・ヤコブ病 / 視床型プリオン病 / 医原性クロイツフェルトヤコブ病 / 医原性プリオン病 / 獲得型CJD / CJD / 衛生 / 臨床 / 蛋白質 / 脳神経疾患 … More Except Principal Investigator ＳＦＩ / ＦＦＩ / 新しいプリオン分類 / SFI / FFI / プリオン / M2C(lv) prion / M2C(sv) prion / thalamic form / fatal familial insomnia / ウイルス / 脳・神経 / 蛋白質 / 脳神経疾患 / プリオン病 Less

視床型プリオン病の脳内プリオン分布が病理像に及ぼす影響Principal Investigator
- Principal Investigator
  
  竹内敦子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tohoku University
International study to establish a new prion identified with fatal familial or sporadic insomnia.
- Principal Investigator
  
  KITAMOTO Tetsuyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tohoku University
Neuropathological studies of thalamic form of Creutzfeldt-Jakob disease using protein misfolding cyclic amplificationPrincipal Investigator
- Principal Investigator
  
  Takeuchi Atsuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tohoku University
Rapid diagnosis of aqcuired Creutzfeldt-jakob disease with protein misfolding cyclic anplificationPrincipal Investigator
- Principal Investigator
  
  Takeuchi Atsuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Characterization of Creutzfeldt-Jakob disease strains with protein misfolfing cyclic amplificationPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Atsuko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
濾胞樹状細胞からのプリオン神経侵入経路の解明
- Principal Investigator
  
  小林篤史
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
Assessment of prion inactivation with quantitative Protein Misfolding Cyclic AmplificationPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Atsuko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tohoku University

All 2023 2021 2019 2018 2017 2016 2015 2013 2012 2011 2009

All Journal Article Presentation

[Journal Article] Preventive or promotive effects of PRNP polymorphic heterozygosity on the onset of prion disease2023
- Author(s)
  Kai Hideaki、Teruya Kenta、Takeuchi Atsuko、Nakamura Yoshikazu、Mizusawa Hidehiro、Yamada Masahito、Kitamoto Tetsuyuki
- Journal Title
  
  Heliyon
  
  Volume: 9 Issue: 3 Pages: e13974-e13974
- DOI
  10.1016/j.heliyon.2023.e13974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07531, KAKENHI-PROJECT-23K05036
[Journal Article] A point mutation in GPI-attachment signal peptide accelerates the development of prion disease2023
- Author(s)
  Kobayashi Atsushi、Hirata Tetsuya、Shimazaki Taishi、Munesue Yoshiko、Aoshima Keisuke、Kimura Takashi、Nio-Kobayashi Junko、Hasebe Rie、Takeuchi Atsuko、Matsuura Yuichi、Kusumi Satoshi、Koga Daisuke、Iwasaki Yasushi、Kinoshita Taroh、Mohri Shirou、Kitamoto Tetsuyuki
- Journal Title
  
  Acta Neuropathologica
  
  Volume: 145 Issue: 5 Pages: 637-650
- DOI
  10.1007/s00401-023-02553-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07261, KAKENHI-PROJECT-21K07062, KAKENHI-PROJECT-22K07531, KAKENHI-PROJECT-22K15357, KAKENHI-PROJECT-21K06727, KAKENHI-PROJECT-21H02415, KAKENHI-PROJECT-23K23773
[Journal Article] Genetic Creutzfeldt-Jakob disease‐M232R with the cooccurrence of multiple prion strains, M1+ M2C + M2T: Report of an autopsy case2021
- Author(s)
  Shintaku Masayuki、Nakamura Takeshi、Kaneda Daita、Shinde Akiyo、Kusaka Hirofumi、Takeuchi Atsuko、Kitamoto Tetsuyuki
- Journal Title
  
  Neuropathology
  
  Volume: - Issue: 3 Pages: 40-56
- DOI
  10.1111/neup.12722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0213, KAKENHI-PROJECT-18H02738, KAKENHI-PROJECT-18K07490, KAKENHI-PROJECT-19K22588
[Journal Article] Two distinct prions in fatal familial insomnia and its sporadic form2019
- Author(s)
  Takeuchi Atsuko、Mohri Shirou、Kai Hideaki、Tamaoka Akira、Kobayashi Atsushi、Mizusawa Hidehiro、Iwasaki Yasushi、Yoshida Mari、Shimizu Hiroshi、Murayama Shigeo、Kuroda Shigetoshi、Morita Masanori、Parchi Piero、Kitamoto Tetsuyuki
- Journal Title
  
  Brain Communications
  
  Volume: 1 Issue: 1
- DOI
  10.1093/braincomms/fcz045
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05963, KAKENHI-PROJECT-18K07490, KAKENHI-PROJECT-19K07841
[Journal Article] A domain responsible for spontaneous conversion of bank vole prion protein2018
- Author(s)
  Kobayashi Atsushi、Matsuura Yuichi、Takeuchi Atsuko、Yamada Masahito、Miyoshi Ichiro、Mohri Shirou、Kitamoto Tetsuyuki
- Journal Title
  
  Brain Pathology
  
  Volume: 29 Issue: 2 Pages: 155-163
- DOI
  10.1111/bpa.12638
- NAID
  120006803949
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05963, KAKENHI-PROJECT-18K07490, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-18H02738, KAKENHI-PROJECT-17K07129
[Journal Article] Application of protein misfolding cyclic amplification for the rapid diagnosis of acquired Creutzfeldt-Jakob disease2017
- Author(s)
  Takeuchi A, Kobayashi A, Morita M, Kitamoto T
- Journal Title
  
  Medical Research Archives
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09307
[Journal Article] Application of protein misfolding cyclic amplification for the rapid diagnosis of acquired Creutzfeldt-Jakob disease.2017
- Author(s)
  Takeuchi A, Kobayashi A, Morita M, Kitamoto T
- Journal Title
  
  Medical Research Archives
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09307
[Journal Article] Distinctive properties of plaque-type dura mater graft-associated Creutzfeldt-Jakob disease in cell-protein misfolding cyclic amplification2016
- Author(s)
  Atsuko Takeuchi, Atsushi Kobayashi, Piero Parchi, Masahito Yamada, Masanori Morita, Shusei Uno and Tetsuyuki Kitamoto
- Journal Title
  
  Laboratory Investigation
  
  Volume: in press Issue: 5 Pages: 581-7
- DOI
  10.1038/labinvest.2016.27
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09307, KAKENHI-PROJECT-26670435, KAKENHI-PROJECT-25257506, KAKENHI-PROJECT-16K18790
[Journal Article] Characterization of variant Creutzfeldt-Jakob disease prions in prion protein-humanized mice carrying distinct codon 129 genotypes2013
- Author(s)
  Takeuchi A, Kobayashi A, Ironside JW, Mohri S, Kitamoto T.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 21659-21666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790871
[Journal Article] Characterization of variant Creutzfeldt-Jakob disease prions in prion protein-humanized mice carrying distinct codon 129 genotypes.2013
- Author(s)
  Takeuchi A, Kobayashi A, Ironside JW, Mohri S, Kitamoto T.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 21659-21666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790871
[Journal Article] Deduction of the evaluation limit and termination timing of multi-round protein misfolding cyclic amplification from a titration curve2011
- Author(s)
  Atsuko Takeuchi, Mayumi Komiya, Tetsuyuki Kitamoto, Masanori Morita
- Journal Title
  
  Microbiology and Immunology
  
  Volume: (未定印刷中)
- NAID
  10031121496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791343
[Journal Article] Heparin enhances the cell-protein misfolding cyclic amplification efficiency of variant Creutzfeldt-Jakob disease.2011
- Author(s)
  Yokoyama T, Takeuchi A, Yamamoto M, Kitamoto T, Ironside JW, Morita M.
- Journal Title
  
  Neuroscience Letters. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791343
[Journal Article] Deduction of the evaluation limit and termination timing of multi-round protein misfolding cyclic amplification from a titration curve.2011
- Author(s)
  Takeuchi A, Komiya M, Kitamoto T, Morita M.
- Journal Title
  
  Microbiology and Immunology in press
- NAID
  10031121496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791343
[Presentation] Diagnosis of MMiK type acquired Creutzfeldt-Jakob disease with cell- protein misfolding amplification (PMCA)2017
- Author(s)
  Takeuchi A, Kobayashi A, Morita M, Kitamoto T
- Organizer
  日本認知症学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09307
[Presentation] Identification of the origin of Creutzfeldt-Jakob disease after cadaver-sourced pituitary growth hormone treatment using an amplification property in protein misfolding cyclic amplificatiton2016
- Author(s)
  Takeuchi A, Yamamoto M, Parchi P, HaiK S, Morita M, Kobayashi A, Kitamoto T
- Organizer
  PRION2016
- Place of Presentation
  学術総合センター（東京）
- Year and Date
  2016-05-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09307
[Presentation] cell-PMCA of acquired Creutzfeldt-Jakob disease2015
- Author(s)
  Atsuko Takeuchi, Atsushi Kobayashi, Piero Parchi, Masahito Yamada, Masanori Morita, Shuusei Uno and Tetsuyuki Kitamoto
- Organizer
  Asia Pacific Society of Prion Research
- Place of Presentation
  金沢 (石川県立音楽堂)
- Year and Date
  2015-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09307
[Presentation] Efficient amplificaiton of variant Creutzfeldt-Jacob disease (vCJD) prion spiked into plasma by heparinized cell-protein misfolding cyclic amplification (PMCA)2012
- Author(s)
  Masatoshi Oshita, Takashi Yokoyama, Atsuko Takeuchi, Miyuki Yamamoto, Tetsuyuki Kitamoto, Masanori Morita
- Organizer
  アジア太平洋プリオン研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790871
[Presentation] リコンビナントPrP^cを用いたPMCA法によるヒトプリオンの増幅2009
- Author(s)
  竹内敦子, 山本幸、北本哲之、森田将典
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-21791343

1. Kitamoto Tetsuyuki (20192560)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. 小林篤史 (50431507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 甲斐英朗 (70648261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KOGA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takeuchi Atsuko 竹内 敦子

TAKEUCHI Atsuko 竹内 敦子

Research Projects

Research Products

Co-Researchers

視床型プリオン病の脳内プリオン分布が病理像に及ぼす影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

International study to establish a new prion identified with fatal familial or sporadic insomnia.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neuropathological studies of thalamic form of Creutzfeldt-Jakob disease using protein misfolding cyclic amplificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Rapid diagnosis of aqcuired Creutzfeldt-jakob disease with protein misfolding cyclic anplificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of Creutzfeldt-Jakob disease strains with protein misfolfing cyclic amplificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

濾胞樹状細胞からのプリオン神経侵入経路の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Assessment of prion inactivation with quantitative Protein Misfolding Cyclic AmplificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Preventive or promotive effects of PRNP polymorphic heterozygosity on the onset of prion disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A point mutation in GPI-attachment signal peptide accelerates the development of prion disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic Creutzfeldt-Jakob disease‐M232R with the cooccurrence of multiple prion strains, M1+ M2C + M2T: Report of an autopsy case2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two distinct prions in fatal familial insomnia and its sporadic form2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A domain responsible for spontaneous conversion of bank vole prion protein2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Application of protein misfolding cyclic amplification for the rapid diagnosis of acquired Creutzfeldt-Jakob disease2017

Author(s)

Journal Title

Data Source

[Journal Article] Application of protein misfolding cyclic amplification for the rapid diagnosis of acquired Creutzfeldt-Jakob disease.2017

Author(s)

Journal Title

Takeuchi Atsuko 竹内敦子

TAKEUCHI Atsuko 竹内敦子