CAAVEIRO Jose ＣＡＡＶＥＩＲＯＪｏｓｅ

Researcher Number	00536732
Other IDs
Affiliation (Current)	2025: 九州大学, 薬学研究院, 教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 九州大学, 薬学研究院, 教授 2016 – 2018: 九州大学, 薬学研究院, 准教授 2015: 東京大学, 工学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Structural biochemistry Except Principal Investigator Biofunction/Bioprocess
Keywords	Principal Investigator Antobody / antibody / Antibody / mechanism / molecular interactions / Molecular interactios / Mechanism / protein expression / fc receptor / HIV-1 … More / bnAbs / glycosylation / immunology / structure / hinge / Fc receptor / X-ray Crystallography / Thernodynamics / Pore forming protein / kinetics / pore forming protein / enzyme / sugar / glycan / Kinetics / Thermodynamics / X-ray crystallography / Pore-forming protein / Enzyme / Sugar / Glycan … More Except Principal Investigator 蛋白質間相互作用 / 遷移状態 / 薬学 / 創薬 / 物理化学 / 蛋白質 / 速度論 / 熱力学 / 阻害剤 / 低分子 / 抗体 / 蛋白質-蛋白質相互作用 Less

Understanding the efficacy of therapeutic antibodies through their interaction with cellular receptors.Principal Investigator
- Principal Investigator
  
  CAAVEIRO Jose
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyushu University
Screening and design of ligands regulating the process of protein-protein interactions based on biophysical approaches
- Principal Investigator
  
  Tsumoto Kouhei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
Thermodynamic basis of life: protein-carbohydrate interactionPrincipal Investigator
- Principal Investigator
  
  CAAVEIRO Jose
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
  The University of Tokyo

All 2022 2021 2020 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 黄色ブドウ球菌の鉄取り込み機構：Isdシステム生化学, 90(3), 279-2892018
- Author(s)
  Jose M. M. Caaveiro, 津本浩平
- Total Pages
  11
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] 薬学雑誌, 138(8), 1033-10412018
- Author(s)
  長門石曉, Jose M. M. Caaveiro, 津本浩平次世代の低分子創薬を拓くタンパク質-低分子間相互作用の物理化学的解析
- Total Pages
  9
- Publisher
  日本薬学会
- Data Source
  KAKENHI-PROJECT-16H02420
[Journal Article] Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope2022
- Author(s)
  Torralba Johana、de la Arada Igor、Partida-Hanon Angelica、Rujas Edurne、Arribas Madalen、Insausti Sara、Valotteau Claire、Valle Javier、Andreu David、Caaveiro Jose M. M.、Jimenez Maria Angeles、Apellaniz Beatriz、Redondo-Morata Lorena、Nieva Jose L.
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1-14
- DOI
  10.1038/s42003-022-04219-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03228
[Journal Article] Functional Delineation of a Protein?Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E82022
- Author(s)
  Insausti Sara、Garcia-Porras Miguel、Torralba Johana、Morillo Izaskun、Ramos-Caballero Ander、de la Arada Igor、Apellaniz Beatriz、Caaveiro Jose M. M.、Carravilla Pablo、Eggeling Christian、Rujas Edurne、Nieva Jose L.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 18 Pages: 10767-10767
- DOI
  10.3390/ijms231810767
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03228
[Journal Article] Antibody recognition of complement Factor H reveals a flexible loop involved in Atypical Hemolytic Uremic Syndrome pathogenesis2022
- Author(s)
  Yokoo Takanori、Tanabe Aki、Yoshida Yoko、Caaveiro Jose M.M.、Nakakido Makoto、Ikeda Yoichiro、Fujimura Yoshihiro、Matsumoto Masanori、Entzminger Kevin、Maruyama Toshiaki、Okumura C.J.、Nangaku Masaomi、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: - Issue: 6 Pages: 101962-101962
- DOI
  10.1016/j.jbc.2022.101962
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-21K08272, KAKENHI-PLANNED-21H05090, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H03228
[Journal Article] Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR32022
- Author(s)
  Kinoshita Seisho、Nakakido Makoto、Mori Chinatsu、Kuroda Daisuke、Caaveiro Jose M.M.、Tsumoto Kouhei
- Journal Title
  
  Protein Science
  
  Volume: 31 Issue: 11 Pages: 1-12
- DOI
  10.1002/pro.4450
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05090, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H03228, KAKENHI-PLANNED-19H05766
[Journal Article] High-level expression of human CH2 domain from the Fc region in <i>Pichia pastoris</i> and preparation of anti-CH2 antibodies2021
- Author(s)
  Oyama Kosuke、Ohkuri Takatoshi、Inoue Mao、Caaveiro Jose M M、Ueda Tadashi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 2 Pages: 289-297
- DOI
  10.1093/jb/mvab039
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03228
[Journal Article] Abolition of aggregation of CH2 domain of human IgG1 when combining glycosylation and protein stabilization2021
- Author(s)
  Oyama Kosuke、Ohkuri Takatoshi、Ochi Jinta、Caaveiro Jose M.M.、Ueda Tadashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 558 Pages: 114-119
- DOI
  10.1016/j.bbrc.2021.04.070
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03228
[Journal Article] Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile2021
- Author(s)
  Rujas Edurne、Leaman Daniel P.、Insausti Sara、Carravilla Pablo、Garc?a-Porras Miguel、Largo Eneko、Morillo Izaskun、S?nchez-Eugenia Rub?n、Zhang Lei、Cui Hong、Iloro Ibon、Elortza F?lix、Julien Jean-Philippe、Eggeling Christian、Zwick Michael B.、Caaveiro Jose M.M.、Nieva Jos? L.
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 9 Pages: 102987-102987
- DOI
  10.1016/j.isci.2021.102987
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03228
[Journal Article] Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments2020
- Author(s)
  Rujas Edurne、various authors, Ojida Akio、Domene Carmen、Caaveiro Jose M.M.、Nieva Jose L.
- Journal Title
  
  Cell Reports
  
  Volume: 32 Issue: 7 Pages: 108037-108037
- DOI
  10.1016/j.celrep.2020.108037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03228
[Journal Article] Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody.2018
- Author(s)
  Miyanabe, K., Akiba, H., Kuroda, D., Nakakido, M., Kusano-Arai, O., Iwanari, H., Hamakubo, T., Caaveiro, J.M.M., and Tsumoto, K.
- Journal Title
  
  J. Biochem.
  
  Volume: in press Issue: 1 Pages: 65-76
- DOI
  10.1093/jb/mvy032
- NAID
  40021625331
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420
[Journal Article] Tyrosine sulfation restricts the conformational ensemble of a flexible peptide, strengthening the binding affinity for an antibody2018
- Author(s)
  K. Miyanabe, T. Yamashita, Y. Abe, H. Akiba, Y. Takamatsu, M. Nakakido, T. Hamakubo, T. Ueda, JMM. Caaveiro, and K. Tsumoto
- Journal Title
  
  Biochemistry
  
  Volume: 57 Issue: 28 Pages: 4177-4185
- DOI
  10.1021/acs.biochem.8b00592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0103, KAKENHI-PROJECT-15H05752, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-17H06109
[Journal Article] Biophysical Analysis of the Protein-Small Molecule Interactions to Develop Small Molecule Drug Discovery2018
- Author(s)
  Nagatoishi S, Caaveiro JMM, Tsumoto K.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 8 Pages: 1033-1041
- DOI
  10.1248/yakushi.17-00211-2
- NAID
  130007429352
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-08-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
[Journal Article] Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin2018
- Author(s)
  Takumi Tashima , Satoru Nagatoishi, Jose M.M. Caaveiro, Makoto Nakakido, Hiroshi Sagara, Osamu Kusano-Arai, Hiroko Iwanari, Hitomi Mimuro, Takao Hamakubo, Shin-ichi Ohnuma and Kouhei Tsumoto
- Journal Title
  
  Communications Biology
  
  Volume: 1:33 Issue: 1 Pages: 1-10
- DOI
  10.1038/s42003-018-0038-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17J10207, KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K19551, KAKENHI-PLANNED-18H05425
[Journal Article] Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column2018
- Author(s)
  Kiyoshi M, Caaveiro JMM, Tada M, Tamura H, Tanaka T, Terao Y, Morante K, Harazono A, Hashii N, Shibata H, Kuroda D, Nagatoishi S, Oe S, Ide T, Tsumoto K, Ishii-Watabe A
- Journal Title
  
  Scientific Reports
  
  Volume: 8:3955 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41598-018-22199-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18113, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-15K06962
[Journal Article] Discovery and Optimization of Inhibitors of the Parkinson’s Disease Associated Protein DJ-12018
- Author(s)
  Tashiro Shinya、Caaveiro Jose M. M.、Nakakido Makoto、Tanabe Aki、Nagatoishi Satoru、Tamura Yasushi、Matsuda Noriyuki、Liu Dali、Hoang Quyen Q.、Tsumoto Kouhei
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 13 Issue: 9 Pages: 2783-2793
- DOI
  10.1021/acschembio.8b00701
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H02443, KAKENHI-PROJECT-17J07322, KAKENHI-PROJECT-17K19338, KAKENHI-PROJECT-15H05705, KAKENHI-PROJECT-16H04710
[Journal Article] Glycosylation of IgG-Fc: a molecular perspective2017
- Author(s)
  Kiyoshi Masato、Tsumoto Kouhei、Ishii-Watabe Akiko、Caaveiro Jose M M
- Journal Title
  
  International Immunology
  
  Volume: 29 Issue: 7 Pages: 311-317
- DOI
  10.1093/intimm/dxx038
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962
[Journal Article] Functional contacts between MPER and the anti-HIV-1 broadly neutralizing antibody 4E10 extend into the core of the membrane2017
- Author(s)
  Rujas, E., Insausti, S., Garcia-Porras, M., Sanchez-Eugenia, R., Tsumoto, K., Nieva, J.L., and Caaveiro, J.M.M.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 429 Issue: 8 Pages: 1213-1226
- DOI
  10.1016/j.jmb.2017.03.008
- NAID
  120006328970
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420
[Journal Article] Peripheral membrane interactions boost the engagement by an anti HIV-1 broadly neutralizing antibody2017
- Author(s)
  Rujas, E., Caaveiro, J.M.M., Insausti, S., Garcia-Porras, M., Tsumoto, K., and Nieva, J.L.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 292 Issue: 13 Pages: 5571-5583
- DOI
  10.1074/jbc.m117.775429
- NAID
  120006328971
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011
[Journal Article] Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin2017
- Author(s)
  S. Kudo, J. M. M. Caaveiro, S. Nagatoishi, T. Miyafusa, T. Matsuura, Y. Sudou, and K. Tsumoto
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 39518-39518
- DOI
  10.1038/srep39518
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011
[Journal Article] Haemolytic actinoporins interact with carbohydrates using their lipid-binding module.2017
- Author(s)
  Tanaka K, Caaveiro JMM, Morante K and Tsumoto K.
- Journal Title
  
  Philos. Trans. R. Soc. B.
  
  Volume: 372 Issue: 1726 Pages: 20160216-20160216
- DOI
  10.1098/rstb.2016.0216
- NAID
  120006328969
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-15K06962
[Journal Article] In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis.2016
- Author(s)
  Sigala PA, Morante K, Tsumoto K, Caaveiro JM, Goldberg DE.
- Journal Title
  
  Biochemistry
  
  Volume: 55 Issue: 34 Pages: 4836-4849
- DOI
  10.1021/acs.biochem.6b00562
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Journal Article] Differential effect of membrane composition on the pore forming ability of four different sea anemone actinoporins2016
- Author(s)
  Garcia-Linares, S., Rivera-de-Torre, E., Morante, K., Tsumoto, K., Caaveiro, J.M.M., Gavilanes, J.G., Slotte, J.P., and Martinez-del-Pozo, A.
- Journal Title
  
  Biochemistry
  
  Volume: 55 Issue: 48 Pages: 6630-6641
- DOI
  10.1021/acs.biochem.6b01007
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420
[Journal Article] Identification of a membrane-bound prepore species clarifies the lytic mechanism of actinoporins2016
- Author(s)
  Morante, K., Bellomio, A., Gil-Carton, D., Redondo-Morata, L., Sot, J., Scheuring, S., Valle, M., Gonzalez-Manas, J.M., Tsumoto, K., and Caaveiro, J.M.M.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 37 Pages: 19210-19219
- DOI
  10.1074/jbc.m116.734053
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420
[Journal Article] Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface2016
- Author(s)
  Rujas, E., Caaveiro, J.M.M., Partida-Hanon, A., Gulzar, N., Morante, K., Apellaniz, B., Garcia-Porras, M., Bruix, M., Tsumoto, K., Scott, J.K., Jimenez, M.A., and Nieva, J.L.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 38177-38177
- DOI
  10.1038/srep38177
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420
[Journal Article] Adhesive dimerization of human P-cadherin catalyzed by a chaperone-like mechanism2016
- Author(s)
  Kudo, S., Caaveiro, J.M.M., and Tsumoto, K.
- Journal Title
  
  Structure
  
  Volume: 24 Issue: 9 Pages: 1523-1536
- DOI
  10.1016/j.str.2016.07.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420
[Journal Article] Structural and thermodynamics basis of epitope binding to neutralizing and non-neutralizing forms of the anti-HIV-1 4E10 antibody2015
- Author(s)
  Rujas, E., Gulzar, N., Morante, K., Tsumoto, K., Scott, J.K., Nieva, J.L. and Caaveiro, J.M.M.
- Journal Title
  
  Journal of Virology
  
  Volume: 89 Issue: 23 Pages: 11975-11991
- DOI
  10.1128/jvi.01793-15
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115
[Journal Article] Bidirectional transformation of a protein between its Native Water-Soluble and Transmembrane Conformations.2015
- Author(s)
  Tanaka, K., Caaveiro, J.M.M., and Tsumoto, K.
- Journal Title
  
  Biochemistry
  
  Volume: 54 Issue: 46 Pages: 6863-6866
- DOI
  10.1021/acs.biochem.5b01112
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J07513, KAKENHI-PROJECT-24000011
[Journal Article] Structural Analysis of Fc/FcγR Complexes: A Blueprint for Antibody Design.2015
- Author(s)
  Caaveiro, J.M.M., Kiyoshi, M. and Tsumoto, K.
- Journal Title
  
  Immunological Reviews
  
  Volume: 268 Issue: 1 Pages: 201-221
- DOI
  10.1111/imr.12365
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25000006
[Presentation] Structural, physicochemical and computational analysis to reveal the mechanism of recognition of phosphorylated antigen by an antibody2018
- Author(s)
  KAWADE, Raiji、AKIBA, Hiroki; NAKAKIDO, Makoto; KURODA, Daisuke; MARUYAMA, Toshiaki; OKUMURA, Shigeru; ENTZMINGER, Kevin; CAAVEIRO, Jose; TSUMOTO, Kouhei
- Organizer
  日本化学会第98春季年会2018
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] リステリア菌感染におけるE-cadherin-InlA間相互作用を阻害する低分子及びVHHの探索2018
- Author(s)
  山﨑太一、長門石曉、中木戸誠、ホセカアベイロ、三室仁美、津本浩平
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 病原性微生物における鉄獲得関連蛋白質の物理化学解析と新規抗菌剤の探索2018
- Author(s)
  中木戸誠、妹尾暁暢、サンドラバレンシアノ、星野将人、相川知宏、長門石曉、ホセカアベイロ、中川一路、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Role of linker region in heme transporter IsdH from Staphylococcus aureus2018
- Author(s)
  バレンシアノサンドラ、シュスコタチアナ、中木戸誠、カアベイロホセ、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 結晶構造と変異導入解析によるウサギ抗体のリン酸基認識機構の解明2017
- Author(s)
  河出来時、秋葉宏樹、カアベイロホセ、奥村繁、丸山俊昭、Kevin Entzminger 、津本浩平
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Thermodynamic analysis of the recognition of a flexible peptide by an antibody2017
- Author(s)
  Kouichi Miyanabe, Hiroki Akiba, Jose M. Caaveiro, Disuke Kuroda, Kouhei Tsumoto
- Organizer
  日本化学会第97春季年会(2017)
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 次世代の低分子創薬を拓く蛋白質-低分子間相互作用の物理化学的解析2017
- Author(s)
  長門石曉、カアベイロホセ、津本浩平
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Molecular recognition phenomena involving proteins of therapeutic interest.2017
- Author(s)
  Caaveiro J.M.M.
- Organizer
  3rd HU-TMU-KU Joint Symposium for Pharmaceutical Sciences
- Invited
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] 熱分析から低分子薬剤の探索・設計に挑む2017
- Author(s)
  長門石曉, Caaveiro Jose,　津本浩平
- Organizer
  第30回九州分析化学若手の会春の講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] The Fascinating journey of a metamorphic protein to the cell membrane2017
- Author(s)
  Caaveiro, J.M.M.
- Organizer
  Bioforo 5th Alumni Research Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] Specificity-determining structural elements of antibody against antigen2017
- Author(s)
  Hiroki Akiba, Ryosuke Yoshida, Raiji Kawade, Jose M. Caaveiro, Kouhei Tsumoto
- Organizer
  日本化学会第97春季年会(2017)
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗体によるリン酸基認識機構の結晶構造と熱力学的手法による解析2017
- Author(s)
  河出来時、秋葉宏樹、カアベイロホセ、奥村繁、丸山俊昭、Kevin Entzminger , 津本浩平
- Organizer
  日本化学会第97春季年会(2017)
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗原ペプチドの硫酸化がペプチド－抗体間相互作用に与える影響の熱力学的解析2017
- Author(s)
  宮鍋一紘、秋葉宏樹、高松佑一郎、山下雄史、カアベイロホセ、津本浩平
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Protein-lipid interactions in a pore-forming toxin.2017
- Author(s)
  Tsumoto, K. and Caaveiro, J.M.M.
- Organizer
  55th Annual Meeting of the Biophysical Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] Thermodynamic properties of the transition state in biomolecular recognition phenomena2017
- Author(s)
  Caaveiro, J.M.M.
- Organizer
  23rd Forum of Pharmaceutical Sciences, The Biophysical Society of Japan
- Place of Presentation
  Sapporo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] 抗原配列の硫酸化が抗体との相互作用に与える影響の熱力学的解析2017
- Author(s)
  宮鍋一紘、秋葉宏樹、カアベイロホセ、黒田大祐、中木戸誠、高松佑一郎、山下雄史、津本浩平
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Thermodynamic analysis of the effect of sulfation on a peptide-antibody interaction2017
- Author(s)
  宮鍋一紘、秋葉宏樹、高松佑一郎、山下雄史、カアベイロホセ、津本浩平
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Thermodynamic effects of intramolcular hydrogen bonds within peptide on the peptide-antibody interaction2017
- Author(s)
  Kazuhiro Miyanabe, Hiroki Akiba, Jose Caaveiro, Makoto Nakakido, Daisuke Kuroda, Kouhei Tsumoto
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Thermodynamic tools in fragment-based drug discovery2016
- Author(s)
  Caaveiro, J.M.M.
- Organizer
  2016 UT-PUCC Joint Workshop for Frontiers in Bioengineering and Biomedical Engineering
- Place of Presentation
  Santiago, Chile
- Invited
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] Pore formation assisted by lipids2016
- Author(s)
  Caaveiro, J.M.M.
- Organizer
  Membrane pores: from structure and assembly, to medicine and technology, The Royal Society
- Place of Presentation
  London, UK
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] Principles of Biomolecular Recognition of IgG-Fc by its receptors2016
- Author(s)
  Caaveiro, J.M.M., Kiyoshi, M. and Tsumoto, K.
- Organizer
  Gordon Conference (Antibody Biology and Engineering)
- Place of Presentation
  Galveston, TX, USA
- Year and Date
  2016-03-20
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] Lipids as structural elements in pore formation2016
- Author(s)
  Koldo Morante, Kouji Tanaka, Jose M. Caaveiro, Kouhei Tsumoto
- Organizer
  IMI translocation 2016 - Novel approaches to fight bacteria
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Biomolecular recognition: a structural and physicochemical perspective2016
- Author(s)
  Caaveiro, J.M.M.
- Organizer
  Chile-Japan Academic Forum 2016 at Patagonia
- Place of Presentation
  Puerto Natales, Chile
- Year and Date
  2016-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] コラーゲン線維形成プロセスを制御する蛋白質Osteomodulinの制御機構解析2016
- Author(s)
  田島卓実、長門石暁、カアベイロホセ、中木戸誠、相良洋、大沼信一、津本浩平
- Organizer
  第10回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Structural and mechanistic basis of capsular polysaccharide-synthesizing enzymes CapE/F, and the route to discovery novel inhibitors with antibacterial properties.2015
- Author(s)
  Caaveiro J.M.M., Miyafusa, T., Chigira, T., Nakano, K., Nagatoishi, S. and Tsumoto, K.
- Organizer
  7th International Chemical Congress of Pacific Basin Societies PacificChem
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] Use of thermodynamic tools in the early stages of fragment-based drug discovery2015
- Author(s)
  Caaveiro J.M.M., Kobe, A., Mitani, T. and Tsumoto, K
- Organizer
  7th International Chemical Congress of Pacific Basin Societies PacificChem
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962
[Presentation] Molecular basis of heme transfer between NEAT transporters in Staphylococcus aureus2015
- Author(s)
  Caaveiro, J.M.M., Morante, K., Vu, N., Moriwaki, Y., and Tsumoto, K.
- Organizer
  7th International Chemical Congress of Pacific Basin Societies PacificChem
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962

1. Tsumoto Kouhei (90271866)

# of Collaborated Projects: 2 results

# of Collaborated Products: 37 results
2. 長門石曉 (30550248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 高橋大輔 (70791523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山下雄史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中木戸誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 黒田大祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 田村康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

CAAVEIRO Jose ＣＡＡＶＥＩＲＯ Ｊｏｓｅ

Research Projects

Research Products

Co-Researchers

Understanding the efficacy of therapeutic antibodies through their interaction with cellular receptors.Principal Investigator

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Screening and design of ligands regulating the process of protein-protein interactions based on biophysical approaches

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Thermodynamic basis of life: protein-carbohydrate interactionPrincipal Investigator

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[Book] 黄色ブドウ球菌の鉄取り込み機構：Isdシステム 生化学, 90(3), 279-2892018

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[Book] 薬学雑誌, 138(8), 1033-10412018

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[Journal Article] Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope2022

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[Journal Article] Functional Delineation of a Protein?Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E82022

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[Journal Article] Antibody recognition of complement Factor H reveals a flexible loop involved in Atypical Hemolytic Uremic Syndrome pathogenesis2022

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[Journal Article] Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR32022

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[Journal Article] High-level expression of human CH2 domain from the Fc region in <i>Pichia pastoris</i> and preparation of anti-CH2 antibodies2021

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[Journal Article] Abolition of aggregation of CH2 domain of human IgG1 when combining glycosylation and protein stabilization2021

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[Journal Article] Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile2021

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[Journal Article] Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments2020

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[Journal Article] Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody.2018

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NAID

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[Journal Article] Tyrosine sulfation restricts the conformational ensemble of a flexible peptide, strengthening the binding affinity for an antibody2018

Author(s)

CAAVEIRO Jose ＣＡＡＶＥＩＲＯＪｏｓｅ

[Book] 黄色ブドウ球菌の鉄取り込み機構：Isdシステム生化学, 90(3), 279-2892018