SHIMIZU Atsushi 清水敦史

Researcher Number	00637910
Affiliation (Current)	2021: 和歌山県立医科大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2017 – 2018: 和歌山県立医科大学, 医学部, 博士研究員 2012 – 2017: 和歌山県立医科大学, 医学部, 学内助教 2014 – 2015: 和歌山県立医科大学, 医学部, その他
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator MUC16 / mesothelin / 膵癌 / 膵癌浸潤規定遺伝子 / 浸潤能規定因子 / 新規膵癌治療標的分子 / 膵癌新規治療標的分子 / IPMN / ペプチドワクチン療法 / 膵管内乳頭粘液性腫瘍 … More Except Principal Investigator 膵癌 / iPS細胞 / 樹状細胞 / 膵癌免疫療法 / 癌ワクチン / ペプチドワクチン / がんワクチン療法 / 細胞傷害性Tリンパ球 / iPS / 癌 / 線維化 / 大腸癌 / αーSMA / adiponectin / 線維芽細胞 / 発癌 / アディポネクチン / 膵頭十二指腸切除術 / 術後合併症 / 胆汁 / サイトカイン / 網羅的解析 / 胆道ドレナージ / 胆汁中サイトカイン / 胆管ドレナージ / 膵切除 / 膵切除後合併症 / 診断法 / mesothelin / MUC16 / がんワクチン / カクテルペプチド / ペプチド / 臨床試験 / 膵癌ワクチン Less

Cancer vaccine therapy using peptide pulsed iPS derived DCs for pancreas cancer patientsOngoing
- Principal Investigator
  
  山上裕機
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Wakayama Medical University
Development of novel pancreatic cancer peptide vaccine therapy using invasion regulating genePrincipal Investigator
- Principal Investigator
  
  SHIMIZU Atsushi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Wakayama Medical University
Low invasive treatment using pancreatic cancer vaccine
- Principal Investigator
  
  Hirono Seiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Wakayama Medical University
Development of innovative peptide vaccine therapy using iPS cell-derived dendritic cells against pancreatic cancer patients
- Principal Investigator
  
  Yamaue Hiroki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Wakayama Medical University
Relationship between pancreatic cancer and adiponectin
- Principal Investigator
  
  Masaji Tani
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Shiga University of Medical Science
Model to predict the risk of intra-abdominal abscess after pancreaticoduodenectomy by analysis of cytokine in bile
- Principal Investigator
  
  Kawai Manabu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Wakayama Medical University
Development of cancer peptide vaccine therapy against newly target gene for invasive intraductal papillary mucinous carcinomaPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Atsushi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Wakayama Medical University
Analysis of the mechanism for invasive ability by MUC16 and mesothelin in the pancreatic cancer.Principal Investigator
- Principal Investigator
  
  SHIMIZU Atsushi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Digestive surgery
- Research Institution
  Wakayama Medical University

All 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Intensive perioperative rehabilitation improves surgical outcomes after pancreaticoduodenectomy.2018
- Author(s)
  Kitahata Y, Hirono S, Kawai M, Okada KI, Miyazawa M, Shimizu A, Kobayashi R, Ueno M, Hayami S, Shimokawa T, Kouda K, Tajima F, Yamaue H.
- Journal Title
  
  Langenbecks Arch Surg.
  
  Volume: 403 Pages: 711-718
- DOI
  10.1007/s00423-018-1710-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00044, KAKENHI-PROJECT-18K08655, KAKENHI-PROJECT-17H01580, KAKENHI-PROJECT-16K15623
[Journal Article] Prospective validation of patient fatigue questionnaire (FACIT-F) for fatigue assessment in nab-paclitaxel plus gemcitabine therapy.2018
- Author(s)
  Okada Ken-Ichi、Hirono Seiko、Kawai Manabu、Miyazawa Motoki、Shimizu Atsushi、Kitahata Yuji、Ueno Masaki、Hayami Shinya、Shimokawa Toshio、Yamaue Hiroki
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: - Pages: 121-126
- DOI
  10.3892/mco.2017.1485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K00044, KAKENHI-PROJECT-17H01580
[Journal Article] Transition of serum cytokines following pancreaticoduodenectomy: A subsidiary study of JAPAN-PD.2018
- Author(s)
  Maeda H, Okada KI, Fujii T, Oba MS, Kawai M, Hirono S, Kodera Y, Sho M, Akahori T, Shimizu Y, Ambo Y, Kondo N, Murakami Y, Ohuchida J, Eguchi H, Nagano H, Sakamoto J, Yamaue H.
- Journal Title
  
  Oncol Lett.
  
  Volume: 16 Pages: 6847-6853
- DOI
  10.3892/ol.2018.9422
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01580, KAKENHI-PROJECT-16K15623
[Journal Article] Factors Associated With Invasive Intraductal Papillary Mucinous Carcinoma of the Pancreas.2017
- Author(s)
  Hirono S, Kawai M, Okada KI, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Yanagisawa A, Yamaue H.
- Journal Title
  
  JAMA Surg.
  
  Volume: 152
- DOI
  10.1001/jamasurg.2016.5054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Postoperative Visceral Tissue Edema Assessed by Computed Tomography Is a Predictor for Severe Complications After Pancreaticoduodenectomy.2017
- Author(s)
  Shimizu Atsushi、Kawai Manabu、Hirono Seiko、Okada Ken-ichi、Miyazawa Motoki、Kitahata Yuji、Ueno Masaki、Hayami Shinya、Miyamoto Atsushi、Kimoto Yoshiki、Shimokawa Toshio、Yamaue Hiroki
- Journal Title
  
  J Gastrointest Surg.
  
  Volume: 22 Pages: 77-87
- DOI
  10.1007/s11605-017-3608-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K00044, KAKENHI-PROJECT-17H01580
[Journal Article] Multicenter, randomized, open-label Phase II study comparing S-1 alternate-day oral therapy with the standard daily regimen as a first-line treatment in patients with unresectable advanced pancreatic cancer.2017
- Author(s)
  Yamaue H, Shimizu A, Hagiwara Y, Sho M, Yanagimoto H, Nakamori S, Ueno H, Ishii H, Kitano M, Sugimori K, Maguchi H, Ohkawa S, Imaoka H, Hashimoto D, Ueda K, Nebiki H, Nagakawa T, Isayama H, Yokota I, Ohashi Y, Shirasaka T.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: in press Pages: 813-823
- DOI
  10.1007/s00280-017-3250-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308, KAKENHI-PROJECT-16K15623
[Journal Article] Left Gastric Artery Reconstruction after Distal Pancreatectomy with Celiac Axis En-Bloc Resection: How We Do It.2017
- Author(s)
  Okada KI, Hirono S, Kawai M, Hayami S, Asamura S, Wada Y, Ueno M, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H.
- Journal Title
  
  Gastrointest Tumors.
  
  Volume: 4 Pages: 28-35
- DOI
  10.1159/000469660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01580
[Journal Article] Value of apparent diffusion coefficient prior to neoadjuvant therapy is a predictor of histologic response in patients with borderline resectable pancreatic carcinoma.2017
- Author(s)
  Okada KI, Hirono S, Kawai M, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Hayami S, Kojima F, Yamaue H.
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 24 Pages: 161-168
- DOI
  10.1002/jhbp.430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Phase I Study of Nab-Paclitaxel plus Gemcitabine as Neoadjuvant Therapy for Borderline Resectable Pancreatic Cancer.2017
- Author(s)
  Okada KI, Hirono S, Kawai M, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Hayami S, Yamaue H.
- Journal Title
  
  Anticancer Res.
  
  Volume: 37 Pages: 853-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Evaluation of the efficacy of daikenchuto (TJ -100) for the prevention of paralytic ileus after pancreaticoduodenectomy: A multicenter, double-blind, randomized, placebo-controlled trial.2016
- Author(s)
  Okada K, Kawai M, Hirono S, Fujii T, Kodera Y, Sho M, Nakajima Y, Satoi S, Kwon AH, Shimizu Y, Ambo Y, Kondo N, Murakami Y, Ohuchida J, Eguchi H, Nagano H, Oba MS, Morita S, Sakamoto J, Yamaue H.
- Journal Title
  
  Surgery.
  
  Volume: 159 Pages: 1333-1341
- DOI
  10.1016/j.surg.2015.11.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Impact of treatment duration of neoadjuvant FIRINOX in patients with borderline resectable pancreatic cancer: a pilot trial2016
- Author(s)
  Okada K., Ioka T., et al.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 78(4) Pages: 719-26
- DOI
  10.1007/s00280-016-3121-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04913, KAKENHI-PROJECT-26293308, KAKENHI-PROJECT-16K15623
[Journal Article] Treatment Strategy for Borderline Resectable Pancreatic Cancer With Radiographic Artery Involvement.2016
- Author(s)
  Hirono S, Kawai M, Okada KI, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Yamaue H.
- Journal Title
  
  Pancreas.
  
  Volume: 45 Pages: 1438-1446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Clinicopathological Characteristics of Young Patients With Pancreatic Cancer: An Analysis of Data From Pancreatic Cancer Registry of Japan Pancreas Society.2016
- Author(s)
  Eguchi H, Yamaue H, Unno M, Mizuma M, Hamada S, Igarashi H, Kuroki T, Satoi S, Shimizu Y, Tani M, Tanno S, Hirooka Y, Fujii T, Masamune A, Mizumoto K, Itoi T, Egawa S, Kodama Y, Tanaka M, Shimosegawa T
- Journal Title
  
  Pancreas.
  
  Volume: 45 Pages: 1411-1417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Long-term surveillance is necessary after operative resection for intraductal papillary mucinous neoplasm of the pancreas.2016
- Author(s)
  Hirono S, Kawai M, Okada K, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Yanagisawa A, Yamaue H.
- Journal Title
  
  Surgery.
  
  Volume: 160 Pages: 306-317
- DOI
  10.1016/j.surg.2016.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] A replaced right hepatic artery adjacent to pancreatic carcinoma should be divided to obtain R0 resection in pancreaticoduodenectomy.2015
- Author(s)
  Okada K, Kawai M, Hirono S, Miyazawa M, Shimizu A, Kitahata Y, Tani M, Yamaue H
- Journal Title
  
  Langenbecks Arch Surg
  
  Volume: 400 Pages: 57-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Validation of a Nomogram for Predicting the Probability of Carcinoma in Patients With Intraductal Papillary Mucinous Neoplasm in 180 Pancreatic Resection Patients at 3 High-Volume Centers.2015
- Author(s)
  Shimizu Y, Yamaue H, Maguchi H, Yamao K, Hirono S, Osanai M, Hijioka S, Kanemitsu Y, Sano T, Senda Y, Bhatia V, Yanagisawa A
- Journal Title
  
  Pancreas.
  
  Volume: 44 Pages: 459-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Randomized clinical trial of isolated Roux-en-Y versus conventional reconstruction after pancreaticoduodenectomy.2014
- Author(s)
  Tani M, Kawai M, Hirono S, Okada K, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H
- Journal Title
  
  Br J Surg
  
  Volume: 101 Pages: 1084-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Preservation of the Left Gastric Artery on the Basis of Anatomical Features in Patients Undergoing Distal Pancreatectomy with Celiac Axis En-bloc Resection (DP-CAR).2014
- Author(s)
  Okada K, Kawai M, Tani M, Hirono S, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H
- Journal Title
  
  World J Surg
  
  Volume: 38 Pages: 2980-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Isolated Roux-en-Y anastomosis of the pancreatic stump in a duct-to-mucosa fashion in patients with distal pancreatectomy with en-bloc celiac axis resection.2014
- Author(s)
  Okada K, Kawai M, Tani M, Hirono S, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: 21 Pages: 193-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Journal Article] Preoperative cholangitis during biliary drainage increases the incidence of postoperative severe complications after pancreaticoduodenectomy.2014
- Author(s)
  Kitahata Y, Kawai M, Tani M, Hirono S, Okada K, Miyazawa M, Shimizu A, Yamaue H
- Journal Title
  
  Am J Surg
  
  Volume: 208 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293308
[Presentation] 術後合併症ゼロを目指した安全確実な膵頭十二指腸切除術の術式と周術期管理に関する臨床試験2016
- Author(s)
  川井学，廣野誠子，岡田健一，宮澤基樹，清水敦史，北畑裕司，上野昌樹，速水晋也，宮本篤，山上裕機
- Organizer
  第71回日本消化器外科学会
- Place of Presentation
  徳島県
- Data Source
  KAKENHI-PROJECT-26462072
[Presentation] 進行膵体尾部癌に対する術中温熱化学療法2015
- Author(s)
  赤堀浩也, 塩見尚礼, 前平博充, 村上耕一郎, 北村直美, 河合由紀, 山口剛, 森毅, 園田寛道, 清水智治, 村田聡, 山本寛, 目片英治, 仲成幸, 谷眞至
- Organizer
  日本癌治療学会
- Place of Presentation
  京都
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-26462071
[Presentation] 分枝型IPMNの手術適応ついての検討2014
- Author(s)
  清水敦史
- Organizer
  第114回日本外科学会
- Place of Presentation
  京都
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-26861096
[Presentation] The specific genes related to the invasion process in pancreatic cancer, as demonstrated by genome-wide expression profiling–the role of MUC16 and mesothelin2014
- Author(s)
  Atsushi Shimizu、Seiko Hirono、Masaji Tani、Manabu Kawai、Ken-ichi Okada、Motoki Miyazawa、Yuji Kitahata、Hiroki Yamaue
- Organizer
  11^<th> World Congress of the International Hepato-Pancreato^Biliary Association
- Place of Presentation
  Seoul
- Year and Date
  2014-03-23
- Data Source
  KAKENHI-PROJECT-24890208
[Presentation] The specific genes related to the invasion process in pancreatic cancer, as demonstrated by genome-wide expression profiling – the role of MUC16 and mesothelin2014
- Author(s)
  Atsushi Shimizu
- Organizer
  11th World Congress of the International Hepato-Pancreato-Biliary Association
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24890208
[Presentation] 膵癌における浸潤およびリンパ節転移関連遺伝子を用いた新規治療戦略2013
- Author(s)
  清水敦史
- Organizer
  第 30回日本胆膵病態生理研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24890208
[Presentation] 網羅的遺伝子発現解析を用いた新規膵癌治療標的遺伝子の同定2013
- Author(s)
  清水敦史、廣野誠子,谷眞至,川井学,岡田健一、宮澤基樹,北畑裕司,山上裕機
- Organizer
  第44回膵臓学会
- Place of Presentation
  仙台
- Year and Date
  2013-07-26
- Data Source
  KAKENHI-PROJECT-24890208
[Presentation] 網羅的遺伝子発現解析を用いた新規膵癌治療標的遺伝子の同定2013
- Author(s)
  清水敦史
- Organizer
  第44回日本膵臓学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24890208
[Presentation] The specific genes related to the invasion process in pancreatic cancer、as demonstrated by genome-wide expression profiling–the role of MUC16 and mesothelin2012
- Author(s)
  Atsushi Shimizu、Seiko Hirono、Masaji Tani、Manabu Kawai、Ken-ichi Okada、Motoki Miyazawa、Yuji Kitahata、Hiroki Yamaue
- Organizer
  Pancreas cancer in Kyoto
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24890208
[Presentation] The specific genes related to the invasion process in pancreatic cancer, as demonstrated by genome-wide expression profiling – the role of MUC16 and mesothelin
- Author(s)
  Shimizu Atsushi
- Organizer
  2012 Pancreas cancer in Kyoto
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24890208
[Presentation] The impact of preservation of left gastric artery in distal pacreatectomy with celiac axis en-bloc resection(CP-CAR):Proposal of a novel surgical technique to reduce delayed gastric emptying.
- Author(s)
  Yamaue H, Kawai M, Okada K, Tani M, Hirono S, Miyazawa M, Shimizu A, Kitahata Y
- Organizer
  48th Annual Meeting of Pancreas Club
- Place of Presentation
  America
- Year and Date
  2014-05-02 – 2014-05-03
- Data Source
  KAKENHI-PROJECT-26293308

1. Yamaue Hiroki (20191190)

# of Collaborated Projects: 5 results

# of Collaborated Products: 22 results
2. Kawai Manabu (40398459)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
3. Hirono Seiko (60468288)

# of Collaborated Projects: 5 results

# of Collaborated Products: 20 results
4. 岡田健一 (50407988)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
5. 宮澤基樹 (90549734)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
6. Masaji Tani (60236677)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
7. 尾島敏康 (60448785)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 三宅亨 (70581924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 北畑裕司 (00535338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 勝田将裕 (50464673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIMOKAWA Toshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

SHIMIZU Atsushi 清水 敦史

Research Projects

Research Products

Co-Researchers

Cancer vaccine therapy using peptide pulsed iPS derived DCs for pancreas cancer patientsOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel pancreatic cancer peptide vaccine therapy using invasion regulating genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Low invasive treatment using pancreatic cancer vaccine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of innovative peptide vaccine therapy using iPS cell-derived dendritic cells against pancreatic cancer patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relationship between pancreatic cancer and adiponectin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Model to predict the risk of intra-abdominal abscess after pancreaticoduodenectomy by analysis of cytokine in bile

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of cancer peptide vaccine therapy against newly target gene for invasive intraductal papillary mucinous carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism for invasive ability by MUC16 and mesothelin in the pancreatic cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Intensive perioperative rehabilitation improves surgical outcomes after pancreaticoduodenectomy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prospective validation of patient fatigue questionnaire (FACIT-F) for fatigue assessment in nab-paclitaxel plus gemcitabine therapy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transition of serum cytokines following pancreaticoduodenectomy: A subsidiary study of JAPAN-PD.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Factors Associated With Invasive Intraductal Papillary Mucinous Carcinoma of the Pancreas.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Postoperative Visceral Tissue Edema Assessed by Computed Tomography Is a Predictor for Severe Complications After Pancreaticoduodenectomy.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multicenter, randomized, open-label Phase II study comparing S-1 alternate-day oral therapy with the standard daily regimen as a first-line treatment in patients with unresectable advanced pancreatic cancer.2017

Author(s)

Journal Title

SHIMIZU Atsushi 清水敦史