KATSUKI Yoko 勝木陽子

… Alternative Names

Katsuki Yoko 勝木陽子

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Researcher Number	00645377
Other IDs	https://orcid.org/0000-0002-2549-7426
Affiliation (Current)	2025: 九州大学, 薬学研究院, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 九州大学, 薬学研究院, 助教 2020 – 2022: 京都大学, 生命科学研究科, 特定講師 2020: 京都大学, 生命科学研究科, 特定助教 2018: 京都大学, 生命科学研究科, 特定助教 2017: 京都大学, 放射線生物研究センター, 特定助教 2014 – 2015: 京都大学, 放射線生物研究センター, 研究員 2014: 京都大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related / Risk sciences of radiation and chemicals Except Principal Investigator Basic Section 49010:Pathological biochemistry-related / Biological Sciences / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator SLX4 / DNA修復 / Ubiquitination / FA pathway / ICL repair / フォーカス形成 / ICL修復 / ユビキチン化 / DNA-タンパク質複合体 / 複製ストレス … More / SUMO認識モチーフ / ユビキチン結合ドメイン / lacO-LacI相互作用 / 内因性複製ストレス / BioID / ファンコニ貧血経路 / SLX4/FANCP / ユビキチン化経路 / ファンコニ貧血 … More Except Principal Investigator ファンコニ貧血 / FANCD2 / 複製フォーク / 複製ストレス / チェックポイント / DNA損傷 / 複製フォーク停止 / 複製フォーク分解 / SLFNファミリー / DNAファイバー法 / 癌化学療法 / MRE11 / DNA2 / RAD51 / SLFN11 / ATRIP-ATR / クロマチン / 染色体ストレス / DNA複製フォーク / 非コードDNA / 染色体脆弱部位 / 相同組換え / DNA複製 / ファンコニ貧血経路 / ゲノム安定性 / DNA修復 / DNA損傷応答 / Fanconi anemia / モノユビキチン化 / クロスリンク修復 / end resection / DNA損傷修復 / DNAクロスリンク損傷 / ユビキチン化 / CtIP / Fanconi貧血 Less

複製ストレス応答におけるDNA修復因子SLX4の局在制御ネットワークの解明Principal Investigator
- Principal Investigator
  
  勝木陽子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kyushu University
Elucidation of molecular mechanism for recruitment of SLX4 by BioID-based identification of novel interactorsPrincipal Investigator
- Principal Investigator
  
  Katsuki Yoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kyushu University
  Kyoto University
The role of SLFN11 gene that determines DNA damage sensitivity at the stalled replication forks
- Principal Investigator
  
  Takata Minoru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kyoto University
Elucidation of the ubiquitination pathway mediating recruitment of SLX4 during ICL repairPrincipal Investigator
- Principal Investigator
  
  Katsuki Yoko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Regulatory mechanisms of CtIP nuclease during DNA crosslink repair
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Analysis of disorders defective in the mechanisms for fork stabilization
- Principal Investigator
  
  Minoru Takata
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2018 2017 2015 Other

All Journal Article Presentation

[Journal Article] Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response2023
- Author(s)
  Alvi Erin、Mochizuki Ayako L.、Katsuki Yoko、Ogawa Minori、Qi Fei、Okamoto Yusuke、Takata Minoru、Mu Anfeng
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 1-12
- DOI
  10.1038/s42003-023-05406-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14452, KAKENHI-PROJECT-23K11419, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-21K15362
[Journal Article] RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair2021
- Author(s)
  Katsuki Yoko、Abe Masako、Park Seon Young、Wu Wenwen、Yabe Hiromasa、Yabe Miharu、van Attikum Haico、Nakada Shinichiro、Ohta Tomohiko、Seidman Michael M.、Kim Yonghwan、Takata Minoru
- Journal Title
  
  Cell Reports
  
  Volume: 37 Issue: 4 Pages: 109879-109879
- DOI
  10.1016/j.celrep.2021.109879
- NAID
  120007165816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748, KAKENHI-PROJECT-20K12161, KAKENHI-PROJECT-20K21394
[Journal Article] SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells2021
- Author(s)
  Okamoto Yusuke、Abe Masako、Mu Anfeng、Tempaku Yasuko、Rogers Colette B.、Mochizuki Ayako L.、Katsuki Yoko、Kanemaki Masato T.、Takaori-Kondo Akifumi、Sobeck Alexandra、Bielinsky Anja-Katrin、Takata Minoru
- Journal Title
  
  Blood
  
  Volume: 137 Issue: 3 Pages: 336-348
- DOI
  10.1182/blood.2019003782
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12161, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-20H03450, KAKENHI-PUBLICLY-20H05396, KAKENHI-PROJECT-21H04719
[Journal Article] USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA-RNA helicase DHX92020
- Author(s)
  Matsui M, Sakasai R, Abe M, Kimura Y, Kajita S, Torii W, Katsuki Y, Ishiai M, Iwabuchi K, Takata M, Nishi R.
- Journal Title
  
  Oncogenesis
  
  Volume: 9 Issue: 6 Pages: 60-60
- DOI
  10.1038/s41389-020-00244-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11642, KAKENHI-PROJECT-20K12161, KAKENHI-PROJECT-18K11648
[Presentation] Elucidation of ubiquitin signaling for recruitment of SLX4 during replication-coupled DNA interstrand crosslink repair2023
- Author(s)
  Y. Katsuki, M. Abe, H. Kosako, M. Takata and M. Fujita
- Organizer
  The 19th Ataxia-Telangiectasia workshop (ATW2023Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11419
[Presentation] 複製ストレス応答におけるDNA修復因子SLX4の局在制御機構の解明2023
- Author(s)
  勝木陽子
- Organizer
  第 10 回 DNA 損傷応答ワークショップ
- Data Source
  KAKENHI-PROJECT-23K11419
[Presentation] ヒト染色体上における内因性複製ストレス誘導モデルを用いた修復因子SLX4-XPFの局在制御の解明2023
- Author(s)
  勝木陽子、岡野拓真、藤井純平、松村友輝、吉田和真、藤田雅俊
- Organizer
  第27回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-23K11419
[Presentation] Two distinct ubiquitination pathways coordinating DNA interstrand crosslink repair in human cells2023
- Author(s)
  Yoko Katsuki
- Organizer
  Sussex Japan Genome Stability Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K11419
[Presentation] ヒト染色体上における内因性複製ストレス誘導モデルを用いた修復因子SLX4-XPFの局在制御の解明2023
- Author(s)
  勝木陽子、岡野拓真、藤井純平、松村友輝、吉田和真、藤田雅俊
- Organizer
  第96回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K11419
[Presentation] Two distinct ubiquitination pathways coordinating DNA interstrand crosslink repair in human cells2023
- Author(s)
  Yoko Katsuki
- Organizer
  Sussex Japan Genome Stability Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12161
[Presentation] Elucidation of ubiquitin signaling for recruitment of SLX4 during replication-coupled DNA interstrand crosslink repair2023
- Author(s)
  Y. Katsuki, M. Abe, H. Kosako, M. Takata and M. Fujita
- Organizer
  The 19th Ataxia-Telangiectasia workshop (ATW2023Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12161
[Presentation] ヒト染色体上における内因性複製ストレス誘導モデルを用いた修復因子SLX4-XPFの局在制御機構2023
- Author(s)
  勝木陽子、岡野拓真、藤井純平、松村友輝、吉田和真、藤田雅俊
- Organizer
  第46回日本分子生物学会年会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K11419
[Presentation] 家族性乳癌を抑制する分子ネットワークが制御するゲノムストレス応答機構.2022
- Author(s)
  勝木陽子, 髙田穰, 藤田雅俊
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12161
[Presentation] 複製とカップルしたDNA損傷修復におけるSLX4のユビキチン化経路を介した制御機構の解析2022
- Author(s)
  勝木陽子、安倍昌子、岡野拓真、藤井純平、白石都、西野耕平、小迫英尊、髙田穰、藤田雅俊
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K12161
[Presentation] DNA 損傷感受性および複製ストレス応答増強におけるヒト SLFN11 および関連マウス遺伝子の解析2022
- Author(s)
  Minoru TAKATA, Erin Norah Corrigan ALVI, Ayako L MOCHIZUKI, Yoko KATSUKI, Minori OGAWA,Fei QI, Yusuke OKAMOTO, Anfeng MU
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] 複製依存的DNAクロスリンク修復因子SLX4のユビキチン化経路を介したリクルートの制御機構2022
- Author(s)
  勝木陽子、安倍昌子、髙田穰
- Organizer
  第65回日本放射線影響学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12161
[Presentation] SLFN11とSLFNファミリー機能の統一的理解を目指して2021
- Author(s)
  高田穰1, Alvi Erin1, 小川みのり1, 勝木陽子1, 岡本祐介1, Canela Andres1,2, 望月綾子1, 牟安峰
- Organizer
  2021年日本分子生物学会第44回年会ワークショップ　「あなたの知らないSLFN11の世界」オーガナイザー：村井純子（慶應義塾大学）高田穰（京都大学）
- Invited
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.2021
- Author(s)
  岡本裕介1,3、牟安峰１,2、望月綾子１,2, 勝木陽子１,2, 高折晃史3、高田穰
- Organizer
  第16回血液学若手研究者勉強会（麒麟塾）
- Invited
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] RNF168は複製依存的DNAクロスリンク修復因子SLX4のユビキチン化経路を介したリクルートを制御する2021
- Author(s)
  勝木陽子, 安倍昌子, Haico van Attikum, 中田慎一郎, 鐘巻将人, Yonghwan Kim, 矢部みはる, 矢部普正, 高田穣.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K12161
[Presentation] RNF168は複製依存的DNAクロスリンク修復因子SLX4のユビキチン化経路を介したリクルートを制御する2021
- Author(s)
  勝木陽子, 安倍昌子, Haico van Attikum, 中田慎一郎, 鐘巻将人, Yonghwan Kim, 矢部みはる, 矢部普正, 高田穣.
- Organizer
  第38回染色体ワークショップ・第19回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20K12161
[Presentation] Loss of SLFN11 gene expression rescues the Fanconi anemia phenotype by stabilizing stalled replication forks.2020
- Author(s)
  Yusuke Okamoto, Masako Abe, Mu Anfeng, Yasuko Tempaku, Colette B. Rogers, Ayako L. Mochizuki, Yoko Katsuki1, Masato T. Kanemaki, Akifumi Takaori-Kondo, Alex Sobeck, Anja-Katrin Bielinsky, and Minoru Takata.
- Organizer
  Fanconi Anemia Research Fund Virtual Scientific Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] ファンコニ貧血原因遺伝子SLX4のユビキチン化経路を介した損傷集積メカニズム2020
- Author(s)
  勝木陽子, 安倍昌子, Haico van Attikum, 中田慎一郎, 鐘巻将人, Yonghwan Kim, 矢部みはる, 矢部普正, 高田穣.
- Organizer
  日本遺伝学会第92回大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K12161
[Presentation] RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair.2018
- Author(s)
  Yoko Katsuki, Masako Abe, Haico van Attikum, Masato T. Kanemaki, Shinichiro Nakada, Miharu Yabe, Hiromasa Yabe, Yonghwan Kim, Minoru Takata.
- Organizer
  The 2nd International Symposium on Radiation Therapeutics and Biology. Kyoto University, Kyoto, Japan.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12822
[Presentation] DNAクロスリンク修復因子SLX4のユビキチン化による制御機構.2018
- Author(s)
  勝木陽子, 安倍昌子, 中田慎一郎, 鐘巻将人, 矢部みはる, 矢部普正, 高田穣.
- Organizer
  日本遺伝学会第90回大会（奈良大会）ワークショップ. 奈良先端科学技術大学院大学
- Invited
- Data Source
  KAKENHI-PROJECT-17K12822
[Presentation] DNAクロスリンク修復因子SLX4のユビキチン化による制御機構.2018
- Author(s)
  勝木陽子, 安倍昌子, 中田慎一郎, 鐘巻将人, 矢部みはる, 矢部普正, 高田穣.
- Organizer
  日本放射線影響学会第61回大会ワークショップ. 長崎ブリックホール
- Invited
- Data Source
  KAKENHI-PROJECT-17K12822
[Presentation] RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair2018
- Author(s)
  Yoko Katsuki, Masako Abe, Haico van Attikum, Masato Kanemaki, Shinichiro Nakada, Miharu Yabe, Hiromasa Yabe, Yonghwan Kim, Minoru Takata
- Organizer
  3rd DNA replication/repair structures and cancer conference, 11 Feb 2018 - 14 Feb 2018, Cancun, Mexico
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12822
[Presentation] RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair.2018
- Author(s)
  Yoko Katsuki, Masako Abe, Haico van Attikum, Masato T. Kanemaki, Shinichiro Nakada, Miharu Yabe, Hiromasa Yabe, Yonghwan Kim, Minoru Takata.
- Organizer
  Gordon Research Conference Genomic Instability. The Hong Kong University of Science and Technology, Hong Kong, China.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12822
[Presentation] DNAクロスリンク修復因子SLX4のユビキチン化による制御機構.2018
- Author(s)
  勝木陽子, 安倍昌子, Haico van Attilum, 中田慎一郎, 鐘巻将人, Youghwan Kim, 矢部みはる, 矢部普正, 高田穣.
- Organizer
  第41回日本分子生物学会年会ワークショップ. パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-17K12822
[Presentation] ICL修復因子SLX4はRNF168依存的なユビキチン化経路を介して損傷部位に集積する2017
- Author(s)
  Yoko Katsuki, Masako Abe, Haico van Attikum, Shinichiro Nakada, Masato Kanemaki, Yonghwan Kim, Minoru Takata
- Organizer
  2017年度生命科学系学会合同年次大会・第40回日本分子生物学会年会, 2017年12月8日, 神戸ポートピアホテル
- Invited
- Data Source
  KAKENHI-PROJECT-17K12822
[Presentation] 相同組換えにおけるＲＰＡ２のユビキチン化を介した分解2015
- Author(s)
  稲野将二郎、佐藤浩一、石合正道、勝木陽子、中田慎一郎、胡桃坂仁志、高田　穣
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] ファンコニ貧血経路とそのキータンパク質FANCD2の機能解析
- Author(s)
  高田穣, 勝木陽子, 佐藤浩一, 石合正道, 胡桃坂仁志
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] ファンコニ貧血経路とそのキータンパク質FANCD2の機能解析
- Author(s)
  高田穣, 勝木陽子, 佐藤浩一, 石合正道, 胡桃坂仁志
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  横浜市みなとみらいパシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PLANNED-23114010

1. TAKATA Minoru (30281728)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. UNNO Junya (50614153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Ishiai Masamichi (90298844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 平明日香 (30772777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 牟安峰 (20894455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 望月綾子 (80817148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. ABE masako

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

KATSUKI Yoko 勝木 陽子

Katsuki Yoko 勝木 陽子

Research Projects

Research Products

Co-Researchers

複製ストレス応答におけるDNA修復因子SLX4の局在制御ネットワークの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecular mechanism for recruitment of SLX4 by BioID-based identification of novel interactorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of SLFN11 gene that determines DNA damage sensitivity at the stalled replication forks

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the ubiquitination pathway mediating recruitment of SLX4 during ICL repairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulatory mechanisms of CtIP nuclease during DNA crosslink repair

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of disorders defective in the mechanisms for fork stabilization

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA-RNA helicase DHX92020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Elucidation of ubiquitin signaling for recruitment of SLX4 during replication-coupled DNA interstrand crosslink repair2023

Author(s)

Organizer

Data Source

[Presentation] 複製ストレス応答におけるDNA修復因子SLX4の局在制御機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] ヒト染色体上における内因性複製ストレス誘導モデルを用いた修復因子SLX4-XPFの局在制御の解明2023

Author(s)

Organizer

Data Source

[Presentation] Two distinct ubiquitination pathways coordinating DNA interstrand crosslink repair in human cells2023

Author(s)

Organizer

Data Source

[Presentation] ヒト染色体上における内因性複製ストレス誘導モデルを用いた修復因子SLX4-XPFの局在制御の解明2023

Author(s)

KATSUKI Yoko 勝木陽子

Katsuki Yoko 勝木陽子

[Presentation] DNA 損傷感受性および複製ストレス応答増強におけるヒト SLFN11 および関連マウス遺伝子の解析2022

[Presentation] RNF168は複製依存的DNAクロスリンク修復因子SLX4のユビキチン化経路を介したリクルートを制御する2021

[Presentation] RNF168は複製依存的DNAクロスリンク修復因子SLX4のユビキチン化経路を介したリクルートを制御する2021