Takata Minoru 高田穣

… Alternative Names

TAKATA Minoru 高田穣

高田穰タカダユタ

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Researcher Number	30281728
Other IDs
Affiliation (Current)	2025: 京都大学, 生命科学研究科, 特任教授
Affiliation (based on the past Project Information) *help	2023: 京都大学, 生命科学研究科, 特任教授 2020 – 2022: 京都大学, 生命科学研究科, 教授 2007 – 2017: Kyoto University, 放射線生物研究センター, 教授 2010: 京都大学, 放射性生物研究センター, 教授 2008: 京都大学, 教授 … More 2008: Kyoto University, 放射生物研究センター, 教授 2006: Hiroshima University, Research Institute for Radiation Biology and Medicine, Professor, 原爆放射線医科学研究所, 教授 2000 – 2005: 川崎医科大学, 医学部, 教授 2002: Kawasaki Medical School, Professor, 教授 2000: kawasaki medical scool. immunology (Professor), 医学研究科, 教授 1999: Kyoto Univ. Graduate School of Hed. (Assistant Professor), 医学研究科, 助教授 1999: 京都大学, 大学院・医学研究科, 助教授 1996 – 1998: 京都大学, 医学研究科, 助手 1997: 京都大学, 大学院・医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / Pathological medical chemistry / Risk sciences of radiation and chemicals / Biological Sciences / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / General medical chemistry / 環境影響評価(含放射線生物学) / Biological Sciences / Pathological medical chemistry … More Except Principal Investigator … More Molecular biology / Respiratory organ internal medicine / General medical chemistry / Biological Sciences / Hematology Less
Keywords	Principal Investigator ファンコニ貧血 / DNA修復 / モノユビキチン化 / FANCD2 / DNA repair / ユビキチン化 / 相同DNA組み換え / I-SceI / Fanconi anemia / チェックポイント … More / Rad51 / ジーンターゲティング / estrogen receptor / DNA double strand break / TAT配列 / エストロジェン受容体 / LOH / homologous recombination / XRCC3 / Rad52 / ADH5 / ALDH2 / アルデヒド / DNA損傷修復 / 複製フォーク / 相同組換え / 複製ストレス / リン酸化 / チェックポイントキナーゼ / DT40細胞 / ゲノム安定性 / FANCI / BRCA2 / シスプラチン / DNA損傷 / 複製フォーク停止 / 複製フォーク分解 / SLFNファミリー / DNAファイバー法 / 癌化学療法 / MRE11 / DNA2 / RAD51 / SLFN11 / 脱メチル化酵素 / エピジェネティックリプログラミング / リプログラミング / iPS細胞 / ゲノム損傷 / フォルムアルデヒド / エピゲノム再構成 / ADD syndrome / ADD症候群 / 脱メチル化 / reprogramming / iPS cells / iPS 細胞 / エピゲネティック再構築 / ホルムアルデヒド / DNA 損傷 / 先天性骨髄不全 / アレイCGH / 次世代シーケンサー / ゲノムシーケンス / ゼブラフィッシュ / 原因遺伝子 / RFWD3 / FA経路 / tamoxifen / non-homologous end joining / DNA二重鎖切断修復 / DNA連鎖切断修復 / protein transduction / I-Sce I / プロテイントランスダクション / TAT配 / I-Scel / DNA二重鎖切断 / Chromosome / ionizing radiation / 染色体 / 電離放射線 / sister chromatid exchanges / Rad51 paralogs / DT 40 cells / Rad51ファミリー / 相同組み換え / 複製後修復 / 相同組替え / 姉妹染色分体交換 / BLMヘリケース / Rad51パラログ / ＡＬＤＨ / 再生不良性貧血 / 内因性アルデヒド / ALDH / DNA損傷応答 / クロスリンク修復 / end resection / DNAクロスリンク損傷 / CtIP / Fanconi貧血 / 細胞周期特異的デグロン / Cdt1 / Geminin / Treslin / DNA損傷チェックポイント / ATRIP-ATR / クロマチン / 染色体ストレス / DNA複製フォーク / 非コードDNA / 染色体脆弱部位 / DNA複製 / ファンコニ貧血経路 / コア複合体 / FANCL / FANC1 / 家族性乳がん / メダカ / FAコア複合体 / ゲノム不安定性 / 家族性乳ガン / ヌクレオチド除去修復 / DNA相同組換え / 相同DNA組み換え機構 / 肺ガン細胞株 / Rad51関連遺伝子群 … More Except Principal Investigator DT40 / Rad51 / DNA修復 / 相同DNA組換え / 放射線 / ターゲットインテグレーション / DT40細胞 / 染色体断裂 / 標的組換え / DNA repair / ヌクレオチド除去修復 / ジーンターゲティング / DNA相同組換え / 相同DNA組み換え / チェックポイント / EGFR / 遺伝子改変マウス / 姉妹染色分体交換 / 組み換え修復 / 相同組み換え / 染色体不安定性 / Rad54 / Rad52 / 遺伝子ノックアウト / 遺伝子治療 / Ku / リボソームRNA遺伝子 / 出芽酵母 / 組換え / 細胞老化 / 連携研究 / 非コード機能配列 / クロマチンネットワーク / 反復配列 / クロマチン構造 / 非コードDNA領域 / セントロメア / クロマチン / テロメア / ゲノムの安定性 / 染色体 / ゲノム / インターメア / 非コードDNA / Sister chromatid exchange / DNA polymerase / Homologous DNA recombinatior / Translesion DNA synthesis / DNA replication / DNA damage / DNAポリメラーゼ / 損傷乗り越え / 複製 / DNA損傷 / Rad 51 / Homologous DNA recombination / ionizing radiation / homologous DNA recombination / chemothrapy of cancer / checkpoint / fumorigenesis / 電離放射線 / 標的組み換え / 癌治療 / 発がん / (1)含鉄蛋白質 / 体内被曝 / 含鉄蛋白 / ラット / プリミティブマントル正規化微量原素パターン / 発癌 / 鉄 / 生体内被曝 / ラジウム / 悪性中皮腫 / 非閉塞性肺疾患癌 / mTOR阻害薬 / BIBW2552 / JAK1/2阻害薬 / everolimus / ｍTOR阻害薬 / 用量依存性 / gefitinib / AZD1480 / everolims / NNK / Ogg1ホモノックアウトマウス / bevacizumab / cetuximab / JAK-1/2 inhibitors / everolimus (mTOR阻害薬), / afatinib / EGFR遺伝子改変マウス / SP-C / 非喫煙 / ZD6474 / 分子標的化学予防 / 血管内皮細胞成長因子受容体 / 肺腺癌 / バンデタニブ / ゲフィチニブ / 上皮成長因子受容体 / 化学予防 / 非喫煙者 / 腺癌 / 肺癌 / Bcl-2 / LMP-1 / NK細胞 / Epstein-Barr virus(EBV) / NKリンパ種 / P糖蛋白 / 薬剤耐性 / アポトーシス / latent membrane protein1 / エプスタイン・バーウィルス(EBV) / 鼻腔原発 / NK細胞リンパ腫 / 遺伝子相同組み換え / 染色体異常 / 誘導型ノックアウト / 相同組換え / 胸腺における選択 / アロ抗原 / 組織適合抗原 / T細胞抗原受容体 / MHC拘束性 / キラーT細胞 / 修復 / DNA2重鎖切断 / RAD54 / RAD52 / RAD51 Less

Genome-stabilizing activity of aldehyde catalyzing enzymes that support epigenetic reprogrammingPrincipal Investigator
- Principal Investigator
  
  Takata Minoru
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University
The role of SLFN11 gene that determines DNA damage sensitivity at the stalled replication forksPrincipal Investigator
- Principal Investigator
  
  Takata Minoru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kyoto University
Hunting and analysis of novel genes causing Fanconi anemiaPrincipal Investigator
- Principal Investigator
  
  Takata Minoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Analysis of tissue-specific distribution and function of ALDH isoforms in Fanconi anemia pathwayPrincipal Investigator
- Principal Investigator
  
  Takata Minoru
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Regulatory mechanisms of CtIP nuclease during DNA crosslink repairPrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Analysis of disorders defective in the mechanisms for fork stabilizationPrincipal Investigator
- Principal Investigator
  
  Minoru Takata
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Basic and clinical study of EGFR gene mutation-positive lung cancer using a genetically modified mouse
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Regulation of protein expression using a cell cyclce-specific degron and its application to functional analysisPrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
A basic studyon malignant mesothelioma pathogenesis by internal radiation exposure of radium contained in the iron-containing protein
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
The function of non-coding DNA for genome integrity
- Principal Investigator
  
  Kobayashi Takehiko
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  National Institute of Genetics
Regulation of the ubiquitin system by checkpoint kinases in response to stalled replication forksPrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
ファンコニ貧血経路の真のターゲットは内因性ホルマリンによる蛋白質ゲノム架橋か?Principal Investigator
- Principal Investigator
  
  高田穣
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Regulation of the ubiquitin system by checkpoint kinases in response to stalled replication forksPrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Chemoprevention of Lung Cancer using Epidermal Growth Factor Receptor Transgenic Mice
- Principal Investigator
  
  KIURA Katsuyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Okayama University
Functional analysis of Fanconi anemia genes that are involved in chromosomal stability and tumor preventionPrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
  Hiroshima University
  Kawasaki Medical School
Induction of single DNA double strand break in animal cell genome and its monitoring methodologyPrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  HIROSHIMA UNIVERSITY
  Kawasaki Medical School
Physical monitoring of repair process of chromosomal double stand break induced by simultaneous nuclear introduction of I-SceI endonucleasePrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kawasaki Medical School
Analysis of genetic interactions of DNA repair pathways
- Principal Investigator
  
  TAKEDA Shunichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KYOTO UNIVERSITY
家族性乳癌原因遺伝子Brca2の欠損細胞株作成によるBrca2の機能解析-乳癌由来変異Brca2分子の機能評価システムの構築-Principal Investigator
- Principal Investigator
  
  高田穣
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kawasaki Medical School
NK細胞白血病/リンパ腫の増殖機序と増殖抑制に関する研究
- Principal Investigator
  
  原田実根
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
  Okayama University
Functional analysis of genes involved in maintenance of chromosome stability and homologous recombinationPrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kawasaki Medical School
Development of new assays to evaluate cellular effects of jonizing radiationPrincipal Investigator
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KAWASAKI MEDICAL SCHOOL
ヒト癌細胞シスプラチン感受性決定因子としてのDNA損傷修復分子機構の解析Principal Investigator
- Principal Investigator
  
  高田穣
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
高頻度にターゲットインテグレーションをおこすニワトリ細胞株の相同組換え機構の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
ヒト癌細胞のシスプラチン感受性決定因子としての相同組み換え関連遺伝子群の役割-ノックアウト細胞株と肺癌細胞株による検討-Principal Investigator
- Principal Investigator
  
  高田穣
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
高頻度にターゲットインテグレーションを起すニワトリ細胞株の相同組換え機構の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
遺伝子ターゲッティングの組換え頻度の調節機構の解析-次世代の遺伝子治療への基礎的アプローチ-
- Principal Investigator
  
  園田英一朗
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  Kyoto University
Analysis of homologous DNA recombination using the chicken B-lymphocyte line
- Principal Investigator
  
  TAKEDA Shunichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Reverse Genetic Analysis of Homologous DNA Recombination in Higher Eukaryotes
- Principal Investigator
  
  TAKEDA Shunichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KYOTO UNIVERSITY
染色体安定性の癌化への関わり(DT40細胞を用いた試み)
- Principal Investigator
  
  IWAI Yuko
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
RAD54変異ニワトリBリンパ細胞株の、DNA複製中に起ったDNA損傷の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ニワトリBリンパ細胞株での、RAD遺伝子群の、DNA組換えと、修復機能の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
MHCクラスIとクラスIIの両方の分子を認識できるT細胞のT細胞抗原受容体の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
遺伝子ターゲッティングの組換え頻度を調節する分子同定の試み:次世代の遺伝子治療への基礎的アプローチ
- Principal Investigator
  
  園田英一朗
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  Kyoto University
高頻度ターゲットインテグレーションをおこす鶏細胞株での相同組換え機構の解析
- Principal Investigator
  
  TAKEDA Shunichi
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University

[Book] 先天性骨髄不全症　診療ガイドライン2017．2017
- Author(s)
  矢部普正、高田穣、村松秀樹
- Total Pages
  96
- Publisher
  診断と治療社
- ISBN
  9784787823311
- Data Source
  KAKENHI-PROJECT-15H01738
[Book] DNA Replication, Recombination, and Repair2015
- Author(s)
  Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata.
- Total Pages
  35
- Publisher
  Springer
- Data Source
  KAKENHI-PLANNED-23114010
[Book] The Fanconi Anemia Pathway and Interstrand Cross-Link Repair in DNA Replication, Recombination, and Repair.2015
- Author(s)
  Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata.
- Total Pages
  35
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-26550026
[Book] DNA Replication, Recombination, and Repair2015
- Author(s)
  Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata.
- Total Pages
  35
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-15H01738
[Book] Evaluation of Homologous Recombinational Repair in Chicken B Lymphoma Cell Line, DT40. Methods Mol Biol2011
- Author(s)
  Kitao H, Hirano S, Takata M
- Total Pages
  745
- Data Source
  KAKENHI-PROJECT-21390094
[Book] Establishment of the DNA repair-defective mutants in DT40 cells. Methods Mol Biol
- Author(s)
  Ishiai M, Uchida E, and Takata M
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] A new Fanconi anemia-like disorder, aldehyde degradation deficiency syndrome: two defense mechanisms working together for the genome and hematopoiesis2023
- Author(s)
  高田穣
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 64 Issue: 7 Pages: 639-645
- DOI
  10.11406/rinketsu.64.639
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21394
[Journal Article] Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response2023
- Author(s)
  Alvi Erin、Mochizuki Ayako L.、Katsuki Yoko、Ogawa Minori、Qi Fei、Okamoto Yusuke、Takata Minoru、Mu Anfeng
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 1-12
- DOI
  10.1038/s42003-023-05406-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14452, KAKENHI-PROJECT-23K11419, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-21K15362
[Journal Article] Fanconi anemia and Aldehyde Degradation Deficiency Syndrome: Metabolism and DNA repair protect the genome and hematopoiesis from endogenous DNA damage2023
- Author(s)
  Mu Anfeng、Hira Asuka、Mori Minako、Okamoto Yusuke、Takata Minoru
- Journal Title
  
  DNA Repair
  
  Volume: 130 Pages: 103546-103546
- DOI
  10.1016/j.dnarep.2023.103546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14452, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-21K15362
[Journal Article] Effects of the major formaldehyde catalyzer ADH5 on phenotypes of fanconi anemia zebrafish model2023
- Author(s)
  Mu Anfeng、Cao Zimu、Huang Denggao、Hosokawa Hiroshi、Maegawa Shingo、Takata Minoru
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 10 Pages: 8385-8395
- DOI
  10.1007/s11033-023-08696-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14452, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-21K15362
[Journal Article] AT workshop 2023 -A platform for discussing cutting-edge science in DNA damage signaling, repair, and human disorders-2023
- Author(s)
  Takata M; Harada H
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 9 Pages: 642-645
- DOI
  10.1111/gtc.13054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18274, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-21KK0144, KAKENHI-PROJECT-23K27546
[Journal Article] The ribonuclease domain function is dispensable for <scp>SLFN11</scp> to mediate cell fate decision during replication stress response2023
- Author(s)
  Qi Fei、Alvi Erin、Ogawa Minori、Kobayashi Junya、Mu Anfeng、Takata Minoru
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 9 Pages: 663-673
- DOI
  10.1111/gtc.13056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14452, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-21K15362
[Journal Article] Lack of impact of the <scp>ALDH2</scp> rs671 variant on breast cancer development in Japanese <scp>BRCA1</scp> /2‐mutation carriers2022
- Author(s)
  Mori Tomoharu、Takata Minoru et al.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 6 Pages: 6594-6602
- DOI
  10.1002/cam4.5430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-22K19577, KAKENHI-PROJECT-21K15362, KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748
[Journal Article] RFWD3 and translesion DNA polymerases contribute to PCNA modification dependent DNA damage tolerance2022
- Author(s)
  Kanao Rie、Kawai Hidehiko、Taniguchi Toshiyasu、Takata Minoru、Masutani Chikahide
- Journal Title
  
  Life Science Alliance
  
  Volume: 5 Issue: 12 Pages: e202201584-e202201584
- DOI
  10.26508/lsa.202201584
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12238, KAKENHI-PROJECT-22K12375, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H04335, KAKENHI-PROJECT-21K19843
[Journal Article] Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.2021
- Author(s)
  Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Kazuko Inoue, Keita Kondo, Masato T. Kanemaki, Tomonari Matsuda, Etsuro Ito, Seiji Kojima, Tatsutoshi Nakahata, Seishi Ogawa, Keigo Tanaka, Keitaro Matsuo, Megumu K. Saito, Minoru Takata.
- Journal Title
  
  Blood
  
  Volume: 137 Issue: 15 Pages: 2021-2032
- DOI
  10.1182/blood.2020009111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-20H03450, KAKENHI-PUBLICLY-20H05396, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H03642, KAKENHI-PROJECT-21K15362, KAKENHI-PROJECT-23K21429, KAKENHI-PROJECT-21H04719
[Journal Article] Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress2021
- Author(s)
  Xu Xinlin、Xu Yixi、Guo Ruiyuan、Xu Ran、Fu Congcong、Xing Mengtan、Sasanuma Hiroyuki、Li Qing、Takata Minoru、Takeda Shunichi、Guo Rong、Xu Dongyi
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 28 Issue: 6 Pages: 487-500
- DOI
  10.1038/s41594-021-00602-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04267, KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-16H06279
[Journal Article] SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells2021
- Author(s)
  Okamoto Yusuke、Abe Masako、Mu Anfeng、Tempaku Yasuko、Rogers Colette B.、Mochizuki Ayako L.、Katsuki Yoko、Kanemaki Masato T.、Takaori-Kondo Akifumi、Sobeck Alexandra、Bielinsky Anja-Katrin、Takata Minoru
- Journal Title
  
  Blood
  
  Volume: 137 Issue: 3 Pages: 336-348
- DOI
  10.1182/blood.2019003782
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12161, KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-20H03450, KAKENHI-PUBLICLY-20H05396, KAKENHI-PROJECT-21H04719
[Journal Article] RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair2021
- Author(s)
  Katsuki Yoko、Abe Masako、Park Seon Young、Wu Wenwen、Yabe Hiromasa、Yabe Miharu、van Attikum Haico、Nakada Shinichiro、Ohta Tomohiko、Seidman Michael M.、Kim Yonghwan、Takata Minoru
- Journal Title
  
  Cell Reports
  
  Volume: 37 Issue: 4 Pages: 109879-109879
- DOI
  10.1016/j.celrep.2021.109879
- NAID
  120007165816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748, KAKENHI-PROJECT-20K12161, KAKENHI-PROJECT-20K21394
[Journal Article] Two aldehyde clearance systems are essential to prevent lethal formaldehyde accumulation in mice and humans.2020
- Author(s)
  Dingler FA†, Wang M†, Mu A† (Co-first), ....Takata M, Patel KJ.
- Journal Title
  
  Mol Cell
  
  Volume: 80 Issue: 6 Pages: 996-1012
- DOI
  10.1016/j.molcel.2020.10.012
- NAID
  120006951779
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21394, KAKENHI-INTERNATIONAL-15K21741, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-18H04039, KAKENHI-PROJECT-20H03450
[Journal Article] Replication stress induces accumulation of FANCD2 at central region of large fragile genes.2018
- Author(s)
  Okamoto Y, Iwasaki WM, Kugou K, Takahashi KK, Oda A, Sato K, Kobayashi W, Kawai H, Sakasai R, Takaori-Kondo A, Yamamoto T, Kanemaki MT, Taoka M, Isobe T, Kurumizaka H, Innan H, Ohta K, Ishiai M, Takata M.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 46(6) Issue: 6 Pages: 2932-2944
- DOI
  10.1093/nar/gky058
- NAID
  120006488604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00547, KAKENHI-PROJECT-26291018, KAKENHI-PLANNED-17H06380, KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-17H01408, KAKENHI-PROJECT-16H07295, KAKENHI-PROJECT-16K15095, KAKENHI-PROJECT-15K16127, KAKENHI-PROJECT-18K11648, KAKENHI-PUBLICLY-18H04719, KAKENHI-PUBLICLY-18H05097, KAKENHI-PROJECT-17H00785, KAKENHI-PROJECT-18H02170, KAKENHI-PROJECT-15H04403, KAKENHI-PROJECT-20K20310, KAKENHI-PROJECT-17H03711, KAKENHI-PROJECT-16K18477
[Journal Article] RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination2017
- Author(s)
  Inano Shojiro、Sato Koichi、Katsuki Yoko、Kobayashi Wataru、Tanaka Hiroki、Nakajima Kazuhiro、Nakada Shinichiro、Miyoshi Hiroyuki、Knies Kerstin、Takaori-Kondo Akifumi、Schindler Detlev、Ishiai Masamichi、Kurumizaka Hitoshi、Takata Minoru
- Journal Title
  
  Molecular Cell
  
  Volume: 66 Issue: 5 Pages: 622-634
- DOI
  10.1016/j.molcel.2017.04.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26241014, KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-16H07295
[Journal Article] PARI regulates stalled replication fork proessing to maintain genome stability upon replication stress in mice2017
- Author(s)
  Ayako L. Mochizuki, Ami Katanaya, Eri Hayashi, Mihoko Hosokawa, Emiko Moribe, Akira Motegi, Masamichi Ishiai,Minoru Takata, Gen Kondoh, Hitomi Watanabe, Norio Nakatsuji, and Shinichiro Chuma
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 37 (23) Issue: 23
- DOI
  10.1128/mcb.00117-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00548, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112004, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-15K21098
[Journal Article] Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes.2017
- Author(s)
  Muramatsu H, Okuno Y, Yoshida K, Shiraishi Y, Doisaki S, Narita A, Sakaguchi H, Kawashima N, Wang X, Xu Y, Chiba K, Tanaka H, Hama A, Sanada M, Takahashi Y, Kanno H, Yamaguchi H, Ohga S, Manabe A, Harigae H, Kunishima S, Ishii E, Kobayashi M, Koike K, Watanabe K, Ito E, Takata M, Yabe M, Ogawa S, Miyano S, Kojima S.
- Journal Title
  
  Genet Med.
  
  Volume: - Issue: 7 Pages: 796-802
- DOI
  10.1038/gim.2016.197
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-26293225, KAKENHI-PROJECT-15K09647, KAKENHI-PROJECT-16K09832, KAKENHI-PROJECT-16K10041, KAKENHI-PROJECT-15H04874
[Journal Article] Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia.2017
- Author(s)
  Kerstin Knies, Shojiro Inano, Maria Ramirez, Masamichi Ishiai, Jordi Suralles, Minoru Takata, and Detlev Schindler.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 127 Issue: 8 Pages: 3013-3027
- DOI
  10.1172/jci92069
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Journal Article] Common Variable Immunodeficiency Caused by FANC Mutations2017
- Author(s)
  Sekinaka Y., Mitsuiki N., Imai K., Yabe M., Yabe H., Mitsui-Sekinaka K., Honma K., Takagi M., Arai A., Yoshida K., Okuno Y., Shiraishi Y., Chiba K., Tanaka H., Miyano S., Muramatsu H., Kojima S., Hira A., Takata M., Ohara O., Ogawa S., Morio T., Nonoyama S.
- Journal Title
  
  Journal of clinical immunology
  
  Volume: 37 Issue: 5 Pages: 434-444
- DOI
  10.1007/s10875-017-0396-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-15K09468, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-15K09647
[Journal Article] Defects in HR repair behind the human diseases: FA and HBOC. Endocrine Related Cancer.2016
- Author(s)
  Katsuki Y, Takata M.
- Journal Title
  
  Endocrine Related Cancer.
  
  Volume: 23 Issue: 10 Pages: T19-T37
- DOI
  10.1530/erc-16-0221
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H01738
[Journal Article] Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks.2016
- Author(s)
  Chen Ling, Jing Huang, Zhijiang Yan, Yongjiang Li, Mioko Ohzeki, Masamichi Ishiai, Dongyi Xu, Minoru Takata, Michael Seidman, and Weidong Wang.
- Journal Title
  
  Cell Discov
  
  Volume: 2 Issue: 1 Pages: 16047-16047
- DOI
  10.1038/celldisc.2016.47
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-26281021
[Journal Article] Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells.2016
- Author(s)
  Hashimoto K, Sharma V, Sasanuma H, Tian X, Takata M, Takeda S, Swenberg JA, Nakamura J
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 37 Pages: 59795-59808
- DOI
  10.18632/oncotarget.10928
- NAID
  120005980805
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-16H02953
[Journal Article] The phenotype and clinical course of Japanese Fanconi Anaemia infants is influenced by patient, but not maternal ALDH2 genotype.2016
- Author(s)
  Yabe M, Yabe H, Morimoto T, Fukumura A, Ohtsubo K, Koike T, Yoshida K, Ogawa S, Ito E, Okuno Y, Muramatsu H, Kojima S, Matsuo K, Hira A, Takata M.
- Journal Title
  
  Br J Haematol.
  
  Volume: 175 Issue: 3 Pages: 457-461
- DOI
  10.1111/bjh.14243
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-26253041, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-16K15243
[Journal Article] FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.2016
- Author(s)
  Sato K, Shimomuki M, Katsuki Y, Takahashi D, Kobayashi W, Ishiai M, Miyoshi H, Takata M, Kurumizaka H.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 44 Issue: 22 Pages: 10758-10771
- DOI
  10.1093/nar/gkw876
- NAID
  120006318854
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-16H07295, KAKENHI-PROJECT-26281021
[Journal Article] Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium.2016
- Author(s)
  Tian X, Patel K, Ridpath JR, Chen Y, Zhou YH, Neo D, Clement J, Takata M, Takeda S, Sale J, Wright FA, Swenberg JA, Nakamura J
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 12 Pages: e0167503-e0167503
- DOI
  10.1371/journal.pone.0167503
- NAID
  120005980904
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-15H01738
[Journal Article] Mutations in the Gene Encoding the E2 Conjugating Enzyme UBE2T Cause Fanconi Anemia.2015
- Author(s)
  Hira A, Yoshida K, Sato K, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Shimamoto A, Tahara H, Ito E, Kojima S, Kurumizaka H, Ogawa S, Takata M, Yabe H, Yabe M.
- Journal Title
  
  Am J Hum Genet
  
  Volume: 96 Pages: 1001-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26550026
[Journal Article] Pluripotent cell models of Fanconi anemia identify the early pathological defect in human hemoangiogenic progenitors.2015
- Author(s)
  Suzuki NM, Niwa A, Yabe M, Hira A, Okada C, Amano N, Watanabe A, Watanabe K, Heike T, Takata M, Nakahata T, Saito MK
- Journal Title
  
  Stem Cells Transl Med
  
  Volume: 4 Issue: 4 Pages: 333-338
- DOI
  10.5966/sctm.2013-0172
- NAID
  120005980869
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461591, KAKENHI-PROJECT-26670498, KAKENHI-PROJECT-15K06921, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-26550026
[Journal Article] Conserved overlapping gene arrangement, restricted expression and biochemical activities of DNA polymerase ν; (POLN).2015
- Author(s)
  Takata KI, Tomida J, Reh S, Swanhart LM, Takata M, Hukriede NA, Wood RD.
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 40 Pages: 27278-93
- DOI
  10.1074/jbc.m115.677419
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-26550026
[Journal Article] Human FAN1 promotes strand incision in 5'-flapped DNA complexed with RPA.2015
- Author(s)
  Takahashi D, Sato K, Hirayama E, Takata M, Kurumizaka H.
- Journal Title
  
  J Biochem
  
  Volume: 158 Issue: 3 Pages: 263-70
- DOI
  10.1093/jb/mvv043
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23114010, KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-25250023, KAKENHI-PROJECT-14J06948, KAKENHI-PROJECT-26550026
[Journal Article] Rad18 and Rnf8 facilitate homologous recombination by two distinct mechanisms, promoting Rad51 focus formation and suppressing the toxic effect of nonhomologous end-joining2015
- Author(s)
  Michael Schmid, Akira Motegi (ほか総計106名、代表者は前から63番目)
- Journal Title
  
  Cytogenet. Genome Res.
  
  Volume: 145 Issue: 2 Pages: 78-179
- DOI
  10.1159/000430927
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25340030, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-26550026
[Journal Article] Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.2015
- Author(s)
  Hira A, Yoshida K, Sato K, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Shimamoto A, Tahara H, Ito E, Kojima S, Kurumizaka H, Ogawa S, Takata M, Yabe H, Yabe M.
- Journal Title
  
  Am J Hum Genet.
  
  Volume: 96(6) Issue: 6 Pages: 1001-7
- DOI
  10.1016/j.ajhg.2015.04.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-221S0001, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-26830128, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26310106
[Journal Article] Defective FANCI Binding by a Fanconi Anemia-Related FANCD2 Mutant.2014
- Author(s)
  Sato K, Ishiai M, Takata M, Kurumizaka H.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 12 Pages: e114752-e114752
- DOI
  10.1371/journal.pone.0114752
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-25116002, KAKENHI-PUBLICLY-25131706, KAKENHI-PROJECT-25250023, KAKENHI-PROJECT-26281021, KAKENHI-PROJECT-26550026, KAKENHI-PROJECT-26830128
[Journal Article] Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents2014
- Author(s)
  Yoshifumi Hosono, Takuya Abe, Masamichi Ishiai, M. Nurul Islam, Hiroshi Arakawa, Weidong Wang, Shunichi Takeda, Yutaka Ishii, Minoru Takata, Masayuki Seki, Takemi Enomoto
- Journal Title
  
  Biochimica et Biophysica Acta-Molecular Cell Research
  
  Volume: 1843 Issue: 5 Pages: 1002-1012
- DOI
  10.1016/j.bbamcr.2014.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J07075, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-24310042, KAKENHI-PUBLICLY-25131706, KAKENHI-PROJECT-26550026, KAKENHI-PLANNED-22131002
[Journal Article] Modularized functions of the Fanconi anemia core complex.2014
- Author(s)
  Huang Y, Leung JW, Lowery M, Matsushita N, Wang Y, Shen X, Huong D, Takata M, Chen J, Li L.
- Journal Title
  
  Cell Rep.
  
  Volume: 7 Issue: 6 Pages: 1849-57
- DOI
  10.1016/j.celrep.2014.04.029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24310042, KAKENHI-PROJECT-24590391, KAKENHI-PROJECT-26550026
[Journal Article] The Trp53-Trp53inp1-Tnfrsf10b Pathway Regulates the Radiation Response of Mouse Spermatogonial Stem Cells.2014
- Author(s)
  Kei Ishii, Masamichi Ishiai, Hiroko Morimoto, Mito Kanatsu-Shinohara, Ohtsura Niwa, Minoru Takata, and Takashi Shinohara.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 3 Issue: 4 Pages: 676-89
- DOI
  10.1016/j.stemcr.2014.08.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-24310042, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-25131706, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26281021, KAKENHI-PROJECT-26293064, KAKENHI-PROJECT-26340021, KAKENHI-PROJECT-26550026, KAKENHI-PLANNED-25112003
[Journal Article] FANCD2 Binds CtIP and Regulates DNA-End Resection during DNA Interstrand Crosslink Repair.2014
- Author(s)
  Unno J
- Journal Title
  
  Cell Rep.
  
  Volume: 7 Issue: 4 Pages: 1039-1047
- DOI
  10.1016/j.celrep.2014.04.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22131004, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-25250023, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-26550026, KAKENHI-PROJECT-26830128, KAKENHI-PROJECT-26870356
[Journal Article] Modularized functions of the Fanconi anemia core complex.2014
- Author(s)
  Huang Y, Leung JW, Lowery M, Matsushita N, Wang Y, Shen X, Huong D, Takata M, Chen J, Li L.
- Journal Title
  
  Cell Reports
  
  Volume: 7 Pages: 1849-57
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23114010
[Journal Article] FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair.2014
- Author(s)
  Unno J, Itaya A, Taoka M, Sato K, Tomida J, Sakai W, Sugasawa K, Ishiai M, Ikura T, Isobe T, Kurumizaka H, Takata M.
- Journal Title
  
  Cell Reports
  
  Volume: 7 Pages: 1039-47
- NAID
  120005466588
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23114010
[Journal Article] Expression and purification of human FANCI and FANCD2 using Escherichia coli cells.2014
- Author(s)
  Daisuke Takahashi, Koichi Sato, Mayo Shimomuki, Minoru Takata, Hitoshi Kurumizaka
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 103 Pages: 8-15
- DOI
  10.1016/j.pep.2014.08.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J06948, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-25250023, KAKENHI-PROJECT-26830128
[Journal Article] Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients.2013
- Author(s)
  Hira A, Yoshida K
- Journal Title
  
  Blood
  
  Volume: 122 Issue: 18 Pages: 3206-3209
- DOI
  10.1182/blood-2013-06-507962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04216, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-24310042, KAKENHI-PROJECT-24390262
[Journal Article] NBS1 directly activates ATR independently of MRE11 and TOPBP1.2013
- Author(s)
  Kobayashi M, Hayashi N, Takata M, Yamamoto K.
- Journal Title
  
  Genes Cells.
  
  Volume: 18 Issue: 3 Pages: 238-46
- DOI
  10.1111/gtc.12031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010
[Journal Article] Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model.2013
- Author(s)
  Hayakawa H, Ichihara E, Ohashi K, Ninomiya T, Yasugi M, Takata S, Sakai K, Matsumoto K, Takigawa N, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 11 Pages: 1440-1446
- DOI
  10.1111/cas.12284
- NAID
  120005468272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24300329
[Journal Article] Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency.2013
- Author(s)
  Takeda H, Takigawa N, Ohashi K, Minami D, Kataoka I, Ichihara E, Ochi N, Tanimoto M, Kiura K.
- Journal Title
  
  Mol Cancer Res
  
  Volume: 319 Issue: 2 Pages: 417-423
- DOI
  10.1158/1541-7786.mcr-12-0401
- NAID
  120005359097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010
[Journal Article] A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair2013
- Author(s)
  J Tomida, A Itaya, T Shigechi, J Unno, E Uchida, M Ikura, Y Masuda, S Matsuda J Adachi, M Kobayashi, AR Meetei, Y Maehara, K Yamamoto K Kamiya, A Matsuura, T Matsuda. T Ikura, M Ishiai, M Takata
- Journal Title
  
  Nucleic Acids Research
  
  Volume: VOL. 41 Issue: 14 Pages: 6930-6941
- DOI
  10.1093/nar/gkt467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05844, KAKENHI-PLANNED-22131004, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-23510061, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-24310040, KAKENHI-PROJECT-24310042, KAKENHI-PUBLICLY-25131706, KAKENHI-PROJECT-25281020, KAKENHI-PROJECT-25550031
[Journal Article] DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI2012
- Author(s)
  Koichi Sato. Kazue Toda, Masamichi Ishiai, Minora Takata, Hitoshi Kurumizaka
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 40 Issue: 10 Pages: 4553-4561
- DOI
  10.1093/nar/gks053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02700, KAKENHI-PROJECT-21390094, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131505, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042
[Journal Article] Establishment of the DNA repair-defective mutants in DT40 cells2012
- Author(s)
  Ishiai M, Uchida E, Takata M
- Journal Title
  
  Methods Mol Biol
  
  Volume: (in press)
- NAID
  120004996387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] Mcm8 and Mcm9 form a complex that functions in homologous recombination induced by interstrand crosslinks2012
- Author(s)
  K. Nishimura
- Journal Title
  
  Molecular Cell
  
  Volume: 47 Issue: 4 Pages: 511-522
- DOI
  10.1016/j.molcel.2012.05.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02503, KAKENHI-PROJECT-21681027, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010, KAKENHI-PLANNED-23115003, KAKENHI-PUBLICLY-23127512, KAKENHI-PUBLICLY-23131505
[Journal Article] ATR-Chkl signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity2012
- Author(s)
  Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Gillespie DA, Yamamoto KI, Takata M, Kitao H, Maehara Y
- Journal Title
  
  DNA Repair
  
  Volume: 1(3) Issue: 3 Pages: 247-58
- DOI
  10.1016/j.dnarep.2011.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094, KAKENHI-PROJECT-21590338, KAKENHI-PROJECT-21591702, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-23651046
[Journal Article] JAK2-related pathway induces acquired erlotinib resistance in lung cancer cells harboring an epidermal growth factor receptor-activating mutation2012
- Author(s)
  Harada D, Takigawa N, Ochi N, Ninomiya T, Yasugi M, Kubo T, Takeda H, Ichihara E, Ohashi K, Takata S, Tanimoto M, Kiura K
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 10 Pages: 1795-1802
- DOI
  10.1111/j.1349-7006.2012.02363.x
- NAID
  120005311974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182
[Journal Article] Establishment of the DNA repair-defective mutants in DT40 cells.2012
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  Ishiai M, Uchida E, Takata M.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 920 Pages: 39-49
- DOI
  10.1007/978-1-61779-998-3_4
- NAID
  120004996387
- ISBN
  9781617799976, 9781617799983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131505
[Journal Article] Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair2012
- Author(s)
  Koichi Sato. Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Tachiwana, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka
- Journal Title
  
  The EMBO Journal
  
  Volume: 31 Issue: 17 Pages: 3524-3536
- DOI
  10.1038/emboj.2012.197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02700, KAKENHI-ORGANIZER-20114001, KAKENHI-PLANNED-20114006, KAKENHI-PROJECT-22370063, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PROJECT-24370071, KAKENHI-PROJECT-24570138, KAKENHI-PROJECT-24870027, KAKENHI-PLANNED-20114005, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23114711, KAKENHI-PUBLICLY-23131505
[Journal Article] Establishment of the DNA repair-defective mutants in DT40 cells2012
- Author(s)
  Ishiai M, Uchida E, Takata M
- Journal Title
  
  Methods Mol Biol
  
  Volume: (in press)
- NAID
  120004996387
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23114010
[Journal Article] A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.2012
- Author(s)
  Yan Z, Guo R, Paramasivam M, Shen W, Ling C, Fox D 3rd, Wang Y, Oostra AB, Kuehl J, Lee DY, Takata M, Hoatlin ME, Schindler D, Joenje H, de Winter JP, Li L, Seidman MM, Wang W
- Journal Title
  
  Mol Cell.
  
  Volume: 47 Issue: 1 Pages: 61-75
- DOI
  10.1016/j.molcel.2012.05.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010
[Journal Article] STAT3 expression in activating EGFR-driven adenocarcinoma of the lung2012
- Author(s)
  Takata Saburo, Takigawa Nagio, Segawa Yoshihiko, Kubo Toshio, Ohashi Kadoaki, Kozuki Toshiyuki, Teramoto Norihiro, Yamashita Motohiro, Toyooka Shinichi, Tanimoto Mitsune, Kiura Katsuyuki
- Journal Title
  
  Lung Cancer
  
  Volume: 75 Issue: 1 Pages: 24-29
- DOI
  10.1016/j.lungcan.2011.05.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590995, KAKENHI-PROJECT-23390221
[Journal Article] ATR-ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway2012
- Author(s)
  Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John K.Eykelenboom, Fabio Pessina, Yanbin Zhang, Emi Uchida, Masamichi Ishiai, Noel F.Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata
- Journal Title
  
  Cancer Research
  
  Volume: 72 Issue: 5 Pages: 1149-1156
- DOI
  10.1158/0008-5472.can-11-2904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02700, KAKENHI-PROJECT-21390094, KAKENHI-PROJECT-22310119, KAKENHI-PROJECT-22710052, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131505, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23651046
[Journal Article] Matched sibling donor stem cell transplantation for Fanconi anemia patients with T-cell somatic mosaicism2012
- Author(s)
  Yabe M, Shimizu T, Morimoto T, Koike T, Takakura H, Tsukamoto H, Muroi K, Oshima K, Asami K, Takata M, Yamashita T, Kato S, Yabe H
- Journal Title
  
  Pediatric Transplant
  
  Volume: (印刷中) Issue: 4 Pages: 340-345
- DOI
  10.1111/j.1399-3046.2012.01669.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591262, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23501257, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131503
[Journal Article] The role of SNM1 family nucleases in etoposide-induced apoptosis2011
- Author(s)
  Hosono, Y., Abe, T., Ishiai, M., Takata, M., Enomoto, T., Seki, M.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 410 Issue: 3 Pages: 568-573
- DOI
  10.1016/j.bbrc.2011.06.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21390094, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131505, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23651046
[Journal Article] FancJ/Brip1 helicase protects against genomic losses and gains invertebrate cells2011
- Author(s)
  Kitao, et al
- Journal Title
  
  Genes to Cells
  
  Volume: 16 Issue: 6 Pages: 717-724
- DOI
  10.1111/j.1365-2443.2011.01523.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
[Journal Article] Fanconi anemia : a disorder defective in the DNA damage response2011
- Author(s)
  Kitao H, Takata M
- Journal Title
  
  Int J Hematol
  
  Volume: 93(4) Issue: 4 Pages: 417-24
- DOI
  10.1007/s12185-011-0832-9
- NAID
  10029534160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
[Journal Article] Direct Inhibition of TNF-α Promoter Activity by Fanconi Anemia Prote in FANCD22011
- Author(s)
  Nobuko Matsushita, Yujiro Endo, Koichi Sato, Hitoshi Kurumizaka, Takayuki Yamashita, Minoru Takata, Shigeru Yanagi
- Journal Title
  
  PLoS One
  
  Volume: 6(電子媒体による発表) Issue: 8 Pages: e23324-e23324
- DOI
  10.1371/journal.pone.0023324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02700, KAKENHI-PROJECT-21390094, KAKENHI-PROJECT-21590345, KAKENHI-PROJECT-22310119, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131503, KAKENHI-PROJECT-23501257, KAKENHI-PROJECT-23650195, KAKENHI-PROJECT-23651046
[Journal Article] Predisposition to cancer caused by genetic and functional defects of Mammalian atad52011
- Author(s)
  Bell DW, Sikdar N, Lee KY, Price J C, Chatterjee R, Park HD, Fox J, Ishiai M, Rudd ML, Pollock LM, Fogoros SK, Mohamed H, Hanigan CL ; NISC Comparative Sequencing Program, Zhang S, Cruz P, Renaud G, Hansen NF, Cherukuri PF, Borate B, McManus KJ, Stoepel J
- Journal Title
  
  PLoS Genet
  
  Volume: 7(8) Issue: 8 Pages: e1002245-e1002245
- DOI
  10.1371/journal.pgen.1002245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131505, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23651046
[Journal Article] FancJ/Bripl helicase protects against genomic losses and gains in vertebrate cells2011
- Author(s)
  Kitao H, Nanda I, Sugino RP, Kinomura A, Yamazoe M, Arakawa H, Schmid M, Innan H, Hiom K, Takata M
- Journal Title
  
  Genes to Cells
  
  Volume: 16(6) Pages: 714-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] The involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway2011
- Author(s)
  Yamamoto KN, Kobayashi S, Tsuda M, Kurumizaka H, Takata M, Kono K, Jiricny J, Takeda S, Hirota K
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 108 Issue: 16 Pages: 6492-6496
- DOI
  10.1073/pnas.1018487108
- NAID
  120003072120
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20114001, KAKENHI-PROJECT-21390094, KAKENHI-PROJECT-22310119, KAKENHI-PROJECT-22687001, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
[Journal Article] Fanconi anemia : a disorder defective in the DNA damage response2011
- Author(s)
  Kitao, Takata
- Journal Title
  
  International Journal of Hematology
  
  Volume: 93 Issue: 4 Pages: 417-424
- DOI
  10.1007/s12185-011-0777-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
[Journal Article] Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway2011
- Author(s)
  Rosado IV, Langevin F, Crossan GP, Takata M, Patel KJ
- Journal Title
  
  Nat Struct Mol Biol
  
  Volume: 18(12) Issue: 12 Pages: 1432-4
- DOI
  10.1038/nsmb.2173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
[Journal Article] USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation2011
- Author(s)
  Guervilly JH, Renaud E, Takata M, Rosselli F
- Journal Title
  
  Hum Mol Genet
  
  Volume: 20(11) Issue: 11 Pages: 2171-81
- DOI
  10.1093/hmg/ddr103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
[Journal Article] KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents2010
- Author(s)
  azunori Yoshikiyo, Katja Kratz, Kouji Hirota, Kana Nishihara, Minoru Takata, Hitoshi Kurumizaka, Satoshi Horimoto, Shunichi Takeda and Josef Jiricny.
- Journal Title
  
  PNAS
  
  Volume: 107(50) Issue: 50 Pages: 21553-7
- DOI
  10.1073/pnas.1011081107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.2010
- Author(s)
  Yoshikiyo K, Kratz K, Hirota K, Nishihara K, Takata M, Kurumizaka H, Horimoto S, Takeda S, Jiricny J.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA.2010
  
  Volume: 107 Pages: 21553-21557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.2010
- Author(s)
  Yoshikiyo K, Kratz K, Hirota K, Nishihara K, Takata M, Kurumizaka H, Horimoto S, Takeda S, Jiricny J.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA.2010
  
  Volume: 107 Pages: 21553-21557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumorigenesis in activating epidermal growth factor receptor transgenic mice2009
- Author(s)
  Ohashi K, Takigawa N, Osawa M, Ichihara E, Takeda H, Kubo T, Hirano S, Yoshino T, Takata M, Tanimoto M, Kiura K.
- Journal Title
  
  Can Res 69
  
  Pages: 7088-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line2009
- Author(s)
  Takata M, Ishiai M, Kitao H
- Journal Title
  
  Invited review Mutat Res
  
  Volume: 668(1-2) Issue: 1-2 Pages: 92-102
- DOI
  10.1016/j.mrfmmm.2008.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] Insights from somatic cell genetics using DT40 cellline. Invited review2009
- Author(s)
  Takata M, Ishiai M, Kitao H., et.al.
- Journal Title
  
  Mutation Research Fanconi anemia Special Issue(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line.2009
- Author(s)
  Takata M, Ishiai M, Kitao H
- Journal Title
  
  Mutat Res 668
  
  Pages: 92-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] TheFanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line.2009
- Author(s)
  Takata M., Ishiai M., Kitao H.
- Journal Title
  
  Invited review. Mutat. Res. 668
  
  Pages: 92-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumorigenesis in activating epidermal growth factor receptor transgenic mice2009
- Author(s)
  Ohashi K, Takigawa N, Osawa M, Ichihara E, Takeda H, Kubo T, Hirano S, Yoshino T, Takata M, Tanimoto M, Kiura K.
- Journal Title
  
  Can Res 69
  
  Pages: 7088-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumori genesis in activating epidermal growth factor receptor transgenic mice2009
- Author(s)
  Ohashi K, Takigawa N, Osawa M, Ichihara E, Takeda H, Kubo T, Hirano S, Yoshino T, Takata M, Tanimoto M, Kiura K.
- Journal Title
  
  Can Res 69
  
  Pages: 7088-7095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line2009
- Author(s)
  Takata M, Ishiai M, Kitao H
- Journal Title
  
  Mutat Res 668
  
  Pages: 92-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line2009
- Author(s)
  Takata M, Ishiai M, Kitao H
- Journal Title
  
  Mutat Res 668
  
  Pages: 92-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumorigenesis in activating epidermal growth factor receptor transgenic mice.2009
- Author(s)
  Ohashi K., Takigawa N., Osawa M., Ichihara E., Takeda H., Kubo T., Hirano S., Yoshino T., Takata M., animoto M., Kiura K.
- Journal Title
  
  Cancer Res. 69
  
  Pages: 7088-7095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Chemopreventive effects of gefitinib on nonsmoking-related lung tumorigenesis in activating epidermal growth factor receptor transgenic mice2009
- Author(s)
  Ohashi K, Takigawa N, Osawa M, Ichihara E, Takeda H, Kubo T, Hirano S, Yoshino T, Takata M, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Res
  
  Volume: 69(17) Issue: 17 Pages: 7088-95
- DOI
  10.1158/0008-5472.can-08-4205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line. Invited review.2009
- Author(s)
  Takata M, Ishiai M, Kitao H
- Journal Title
  
  Mutation Research Fanconi anemia special Issue (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Detection of phosphorylation on large proteins by western blotting using Phos-tag containing gel.2008
- Author(s)
  Tomida J., Kitao H., Kinoshita E., Takata., M.
- Journal Title
  
  Nature Protocols 232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC32008
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  Wilson JB, Yamamoto K, Marriott AS, Hussain S, Sung P, Hoatlin ME, Mathew CG, Takata M, Thompson LH, Kupfer GM, Jones NJ.
- Journal Title
  
  Oncogene 27(26)
  
  Pages: 3641-52
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter2008
- Author(s)
  Ohashi K, Rai K, Fujiwara Y, Osawa M, Hirano S, Takata K, Kondo E, Yoshino T, Takata M, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Sci. 99(9)
  
  Pages: 1747-53
- NAID
  10024010760
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Enhancement of radiation induced cell death in chicken Blymphocytes by withaferin A.2008
- Author(s)
  Uma Devi P, Utsumiz H, Takata M, Takeda S., et. al.
- Journal Title
  
  Indian J Exp Biol. 46
  
  Pages: 437-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.2008
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  Ishiai M, Kitao H, Elledge SJ, Takata M., et al
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  Nat Struct Mol Biol. 15
  
  Pages: 1138-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] KU70/80,DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation2008
- Author(s)
  Abe T, Ishiai M, Hosono Y, Yoshimura A, Tada S, Adachi N, Koyama H, Takata M, Takeda S, Enomoto T, Seki M.
- Journal Title
  
  Cell Signal 20(11)
  
  Pages: 1978-85
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.2008
- Author(s)
  Ishiai M., Kitao H., Smogorzewska A., Tomida J., Kinomura A., Uchida E., Saberi A., Kinoshita E., Kinoshita-Kikuta E., Koike T., Tashiro S., Elledge S.J., Takata M.
- Journal Title
  
  Nat. Struc. Mol. Biol. 15
  
  Pages: 1138-1146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway2008
- Author(s)
  Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M.
- Journal Title
  
  Nat Struct Mol Biol 15(11)
  
  Pages: 1138-46
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2, XRCC3.2008
- Author(s)
  Wilson J.B., Yamamoto K., Marriott A.S., Hussain S., Sung P., Hoatlin M.E., Mathew C.G., Takata M., Thompson L.H., Kupfer G.M., Jones N.J.
- Journal Title
  
  Oncogene 27
  
  Pages: 3641-3652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter2008
- Author(s)
  Ohashi K, Rai K, Fujiwara Y, Osawa M, Hirano S, Takata K, Kondo E, Yoshino T, Takata M, Tanimoto M, Kiura K
- Journal Title
  
  99
  
  Pages: 1747-1753
- NAID
  10024010760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion2008
- Author(s)
  Kitao H, Kimura M, Yamamoto K, Seo H, Namikoshi K, Agata Y, Ohta K, Takata M.
- Journal Title
  
  Int Immunol 20(2)
  
  Pages: 277-84
- NAID
  10021239538
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Insights from somatic cell genetics using DT40 cell line. Invited review.2008
- Author(s)
  Takata M, Ishiai M, Kitao H., et. al.
- Journal Title
  
  Mutation Research Fanconi anemia Special Issue (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.2008
- Author(s)
  Kitao H., Kimura M., Yamamoto K., Seo H., Namikoshi K., Agata Y., Ohta K., Takata M.
- Journal Title
  
  Int. Immunol. 20
  
  Pages: 277-284
- NAID
  10021239538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Enhancement of radiation induced cell death in chicken B Iymphocytes by waithaferin A.2008
- Author(s)
  Uma Devi P, Takata M, et al
- Journal Title
  
  Indian J Exp Biol. 46
  
  Pages: 437-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Enhancement of radiation induced cell death in chicken Blymphocytes by withaferin A2008
- Author(s)
  Uma Devi P, Utsumiz H, Takata M, Takeda S., et.al.
- Journal Title
  
  Indian J Exp Biol 46
  
  Pages: 437-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non Small Cell Lung Cancer Cell Line.2007
- Author(s)
  Ogino A., Kitao H., A., Ishiai M., Kozuki T., Takigawa N., Hirano S., Uchida Takata M., Kiura K., Tanimoto M.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 7807-7014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Epidermal growth factor receptor mutation status and adjuvant chemotherapy with uracil tegafur for adenocarcinoma of the lung2007
- Author(s)
  Suehisa H, Toyooka S, Hotta K, Uchida A, Soh J, Fujiwara Y, Matsuo K, Ouchida M, Takata M, Kiura K, Date H.
- Journal Title
  
  J Clin Oncol 25(25)
  
  Pages: 3952-7
- NAID
  130004903139
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non Small Cell Lung Cancer Cell Line2007
- Author(s)
  Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Res. 67(16)
  
  Pages: 7807-14
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation2007
- Author(s)
  Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 357-363
- NAID
  10019481589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway.2007
- Author(s)
  Ling C., Ishiai M., Ali A.M., Medhurst A.L., Neveling K., Kalb R., Yan Z., Xue Y., Oostra A.B., Auerbach A.D., Hoatlin M.E., Schindler D., Joenje H., de Winter J.P., Takata M., Meetei A.R., Wang W.
- Journal Title
  
  EMBO J. 26
  
  Pages: 2104-2114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair.2007
- Author(s)
  Seki S., Ohzeki M., Uchida A., Hirano S., Matsushita N., Kitao H., Oda T., Yamashita T., Kashihara N., Tsubahara A., Takata M., Ishiai M.
- Journal Title
  
  Genes Cells 12
  
  Pages: 299-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Characterization of the short isoform of Helios overexpressed in patients with T-cell malignancies.2007
- Author(s)
  Tabayashi T, Ishimaru F, Takata M, etal.
- Journal Title
  
  Cancer science 98・2
  
  Pages: 182-188
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde.2007
- Author(s)
  Ridpath J.R., Nakamura A., Tano K., Luke A.M., Sonoda E., Arakawa H., Buerstedde J.M., Gillespie D.A., Sale J.E., Yamazoe M., Bishop D.K., Takata M., Takeda S., Watanabe M., Swenberg J.A., Nakamura J. Cells deficient
- Journal Title
  
  Cancer Res. 67
  
  Pages: 11117-11122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair.2007
- Author(s)
  Oestergaard V.H., Langevin F., Kuiken H.J., Pace P., Niedzwiedz W., Simpson L.J., Ohzeki M., Takata M., Sale J.E., Patel K.J.
- Journal Title
  
  Mol. Cell 28
  
  Pages: 798-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway.2007
- Author(s)
  Ling C, Ishiai M, Ali AM, Medhurst AL, Neveling K, Kalb R, Yan Z, Xue Y, Oostra AB, Auerbach AD, Hoatlin ME, Schindler D, Joenje H, de Winter JP, Takata M, Meetei AR, Wang W.
- Journal Title
  
  EMBO J. [Epub ahead of print]
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation.2007
- Author(s)
  Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M.
- Journal Title
  
  Cancer Sci. 98(3)
  
  Pages: 357-63
- NAID
  10019481589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non small cell lung cancer cell line.2007
- Author(s)
  Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Res. 67
  
  Pages: 7807-7814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590895
[Journal Article] genetic analysis of a human disease using chicken system.2007
- Author(s)
  Takata M, Kitao H, Ishiai M. Fanconianemia
- Journal Title
  
  Cytogenet Genome Res. 117
  
  Pages: 346-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress2007
- Author(s)
  Messaoudi L, Yang YG, Kinomura A, Stavreva DA, Yan G, Bortolin-Cavaille ML, Arakawa H, Buerstedde JM, Hainaut P, Cavaille J, Takata M, Van Dyck E.
- Journal Title
  
  Nucleic Acids Res. 35(19)
  
  Pages: 6571-6587
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde2007
- Author(s)
  Ridpath JR, Nakamura A, Tano K, Luke AM, Sonoda E, Arakawa H, Buerstedde JM, Gillespie DA, Sale JE, Yamazoe M, Bishop DK, Takata M, Takeda S, Watanabe M, Swenberg JA, Nakamura J.
- Journal Title
  
  Cancer Res. 67(23)
  
  Pages: 11117-22
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair2007
- Author(s)
  Oestergaard VH, Langevin F, Kuiken HJ, Pace P, Niedzwiedz W, Simpson LJ, Ohzeki M, Takata M, Sale JE, Patel KJ.
- Journal Title
  
  Mol Cell 28(5)
  
  Pages: 798-809
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Characterization of the short isoform of Helios overexpressed in patients with T-cell malignancies.2007
- Author(s)
  Tabayashi T, Ishimaru F, Takata M, Kataoka I, Nakase K, Kozuka T, Tanimoto M.
- Journal Title
  
  Cancer Sci. 98(2)
  
  Pages: 182-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Characterization of the short isoform of Helios overexpressed in patients with T-cell malignancies.2007
- Author(s)
  Tabayashi T, Ishimaru F, Takata M, et al.
- Journal Title
  
  Cancer science 98・2
  
  Pages: 182-188
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair.2007
- Author(s)
  Seki S, Ohzeki M, Uchida A, Hirano S, Matsushita N, Kitao H, Oda T, Yamashita T, Kashihara N, Tsubahara A, Takata M, Ishiai M.
- Journal Title
  
  Genes Cells. 12(3)
  
  Pages: 299-310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Characterization of the short isoform of Helios overexpressed in patients with T-cell malignancies.2007
- Author(s)
  Tabayashi T, Ishimaru F, Takata M, et al.
- Journal Title
  
  Cancer science 98・2
  
  Pages: 182-188
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006
- Author(s)
  Kitao H, Yamamoto K, Matsushita N, Ohzeki M, Ishiai M, Takata M.
- Journal Title
  
  J Biol Chem. 281(30)
  
  Pages: 21312-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006
- Author(s)
  Kitao H., Yamamoto K., Matsushita N., Ohzeki M., Ishiai M., Takata M.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 21312-21320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] 53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis.2006
- Author(s)
  Iwabuchi K, Hashimoto M, Matsui T, Kurihara T, Shimizu H, Adachi N, Ishiai M, Yamamoto K, Tauchi H, Takata M, Koyama H, Date T.
- Journal Title
  
  Genes Cells. 11(8)
  
  Pages: 935-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair.2005
- Author(s)
  Matsushita N, Kitao H, Ishiai M, Nagashima N, Hirano S, Okawa K, Ohta T, Yu DS, McHugh PJ, Hickson ID, Venkitaraman AR, Kurumizaka H, Takata M.
- Journal Title
  
  Mol Cell. 19(6)
  
  Pages: 841-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation-and cisplatin-induced cell death in vertebrate cells.2005
- Author(s)
  Matsushita N, Takami Y, Kimura M, Tachiiri S, Ishiai M, Nakayama T, Takata M.
- Journal Title
  
  Genes Cells. 10(4)
  
  Pages: 321-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair.2005
- Author(s)
  Matsushita N., Kitao H., Ishiai M., Nagashima N., Hirano S., Okawa K., Ohta T., Yu D.S., McHugh P.J., Hickson I.D., Venkitaraman A.R., Kurumizaka H., Takata M.
- Journal Title
  
  Mol. Cell 19
  
  Pages: 841-847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.2005
- Author(s)
  Nojima K, Hochegger H, Saberi A, Fukushima T, Kikuchi K, Yoshimura M, Orelli BJ, Bishop DK, Hirano S, Ohzeki M, Ishiai M, Yamamoto K, Takata M, Arakawa H, Buerstedde JM, Yamazoe M, Kawamoto T, Araki K, Takahashi JA, Hashimoto N, Takeda S, Sonoda E.
- Journal Title
  
  Cancer Res. 65(24)
  
  Pages: 11704-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Conserved domains in the chicken homologue of BRCA2.2001
- Author(s)
  Takata M. et al.
- Journal Title
  
  Mol Cell Bio1. 21
  
  Pages: 2858-2866
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213059
[Journal Article] Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs.2001
- Author(s)
  Takata M. et al.
- Journal Title
  
  Nature. 412
  
  Pages: 921-926
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213059
[Journal Article] Fanconi anemia : a disorder defective in the DNA damage response. "Progress in Hematology review series"
- Author(s)
  Kitao H, Takata M.
- Journal Title
  
  Int.J.Hematol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] Fanconi anemia : a disorder defective in the DNA damage response."Progress in Hematology review series"
- Author(s)
  Kitao H, Takata M.
- Journal Title
  
  Int.J.Hematol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells.
- Author(s)
  Kitao H, Nanda I, Sugino RP, Kinomura A, Yamazoe M, Arakawa H, Schmid M, Innan H, Hiom K, Takata M.
- Journal Title
  
  Genes Cells
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] The involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.
- Author(s)
  Yamamoto KY, Kobayashi S, Kurumizaka H, Takata M, Kono K, Jiricny J, Takeda S, Hirota K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA.
  
  Volume: (in press)
- NAID
  120003072120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells.
- Author(s)
  Kitao H, Nanda I, Sugino RP, Kinomura A, Yamazoe M, Arakawa H, Schmid M, Innan H, Hiom K, Takata M.
- Journal Title
  
  Genes Cells
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation.
- Author(s)
  Guervilly JH, Renaud E, Takata M, Rosselli F.
- Journal Title
  
  Hum.Mol Genet.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20651014
[Journal Article] USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation.
- Author(s)
  Guervilly JH, Renaud E, Takata M, Rosselli F.
- Journal Title
  
  Hum.Mol.Genet.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Journal Article] The involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.
- Author(s)
  Yamamoto KY, Kobayashi S, Kurumizaka H, Takata M, Kono K, Jiricny J, Takeda S, Hirota K.
- Journal Title
  
  Proc.Natl Acad.Sci.USA.
  
  Volume: (in press)
- NAID
  120003072120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] DNA 損傷感受性および複製ストレス応答増強におけるヒト SLFN11 および関連マウス遺伝子の解析2022
- Author(s)
  Minoru TAKATA, Erin Norah Corrigan ALVI, Ayako L MOCHIZUKI, Yoko KATSUKI, Minori OGAWA,Fei QI, Yusuke OKAMOTO, Anfeng MU
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] 抗がん化学療法後の細胞運命を決定する SLFN11 遺伝子とそのファミリー2022
- Author(s)
  Minoru Takata, Anfeng Mu
- Organizer
  第81回日本がん学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] ファンコニ貧血とアルデヒド代謝欠損症候群（ADDS）：DNA 修復とアルデヒド代謝のゲノム安定性と造血における役割2022
- Author(s)
  高田　穣
- Organizer
  第84回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21394
[Presentation] SLFN11とSLFNファミリー機能の統一的理解を目指して2021
- Author(s)
  高田穰1, Alvi Erin1, 小川みのり1, 勝木陽子1, 岡本祐介1, Canela Andres1,2, 望月綾子1, 牟安峰
- Organizer
  2021年日本分子生物学会第44回年会ワークショップ　「あなたの知らないSLFN11の世界」オーガナイザー：村井純子（慶應義塾大学）高田穰（京都大学）
- Invited
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] Discovery of a novel FA-like disorder Aldehyde Degradation Deficiency (ADD) Syndrome caused by ADH5/ALDH2 mutations.2021
- Author(s)
  Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Minako Mori, Yusuke Okamoto, Megumu K. Saito, Minoru Takata.
- Organizer
  2021Fanconi anemia Research Fund Scientific Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21394
[Presentation] SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.2021
- Author(s)
  岡本裕介1,3、牟安峰１,2、望月綾子１,2, 勝木陽子１,2, 高折晃史3、高田穰
- Organizer
  第16回血液学若手研究者勉強会（麒麟塾）
- Invited
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] 新規遺伝性骨髄不全症アルデヒド分解不全(ADD)症候群の発見：代謝異常によって引き起こされるゲノム不安定性2021
- Author(s)
  牟安峰1, 平明日香1, 丹羽明2, 大澤光次郎2, 森美奈子1, 岡本裕介1, 齋藤潤2, 高田穣
- Organizer
  2021年日本分子生物学会第44回年会ワークショップ「ゲノム安定性：その破綻を誘導する分子機構と破綻によりおこるゲノム異常」オーガナイザー：中田慎一郎（大阪大学）、廣田耕志（東京都立大学）
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] Responses to replication stress and human disease mechanisms2021
- Author(s)
  Minoru Takata
- Organizer
  第12回未来先端研究機構　国際シンポジウム “Genome Action”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.2021
- Author(s)
  岡本裕介1,3、牟安峰１,2、望月綾子１,2, 勝木陽子１,2, 高折晃史3、高田穰
- Organizer
  第16回血液学若手研究者勉強会（麒麟塾）
- Invited
- Data Source
  KAKENHI-PROJECT-20K21394
[Presentation] 新規遺伝性骨髄不全症アルデヒド分解不全(ADD)症候群の発見：代謝異常によって引き起こされるゲノム不安定性2021
- Author(s)
  牟安峰1, 平明日香1, 丹羽明2, 大澤光次郎2, 森美奈子1, 岡本裕介1, 齋藤潤2, 高田穣
- Organizer
  2021年日本分子生物学会第44回年会ワークショップ「ゲノム安定性：その破綻を誘導する分子機構と破綻によりおこるゲノム異常」オーガナイザー：中田慎一郎（大阪大学）、廣田耕志（東京都立大学
- Data Source
  KAKENHI-PROJECT-20K21394
[Presentation] Discovery of a novel FA-like disorder Aldehyde Degradation Deficiency (ADD) Syndrome caused by ADH5/ALDH2 mutations2021
- Author(s)
  Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Minako Mori, Yusuke Okamoto, Megumu K. Saito, Minoru Takata.
- Organizer
  2021Fanconi anemia Research Fund Scientific Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] Responses to replication stress and human disease mechanisms2021
- Author(s)
  Minoru Takata
- Organizer
  第12回未来先端研究機構　国際シンポジウム “Genome Action”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21394
[Presentation] Loss of SLFN11 gene expression rescues the Fanconi anemia phenotype by stabilizing stalled replication forks.2020
- Author(s)
  Yusuke Okamoto, Masako Abe, Mu Anfeng, Yasuko Tempaku, Colette B. Rogers, Ayako L. Mochizuki, Yoko Katsuki1, Masato T. Kanemaki, Akifumi Takaori-Kondo, Alex Sobeck, Anja-Katrin Bielinsky, and Minoru Takata.
- Organizer
  Fanconi Anemia Research Fund Virtual Scientific Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03450
[Presentation] Loss of SLFN11 gene expression rescues the Fanconi anemia phenotype by stabilizing stalled replication forks.2020
- Author(s)
  Yusuke Okamoto, Masako Abe, Mu Anfeng, Yasuko Tempaku, Colette B. Rogers, Ayako L. Mochizuki, Yoko Katsuki1, Masato T. Kanemaki, Akifumi Takaori-Kondo, Alex Sobeck, Anja-Katrin Bielinsky, and Minoru Takata.
- Organizer
  Fanconi Anemia Research Fund Virtual Scientific Symposia.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21394
[Presentation] ICL修復因子SLX4はRNF168依存的なユビキチン化経路を介して損傷部位に集積する.2017
- Author(s)
  勝木陽子, 安倍昌子, Haico van Attikum, 中田慎一郎, 鐘巻将人, Yonghwan Kim, 高田穣.
- Organizer
  生命科学系学会合同年次大会ConBio2017, 第40回日本分子生物学会年会ワークショップ.
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Regulation of homologous recombination repair by a novel Fanconi anemia E3 ligase RFWD3/FANCW.2017
- Author(s)
  Minoru Takata
- Organizer
  6th US-Japan DNA Repair Meeting, Clark-Kerr Campus, Berkeley, CA, USA.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Regulation of homologous recombination by a novel FA protein RFWD3/FANCW．2017
- Author(s)
  Minoru Takata
- Organizer
  1st International Symposium on Radiation Therapeutics and Biology (isRTB-2017)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Regulation of homologous recombination by a novel FA protein RFWD3.2017
- Author(s)
  Shojiro Inano, Koichi Sato, Yoko Katsuki, Kerstin Knies, Detlev Schindler, Masamichi Ishiai, Hitoshi Kurumizaka, Minoru Takata.
- Organizer
  FEBS workshop Nucleotide excision repair and crosslink repair - from molecules to mankind. Smolenice, Slovakia.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Pathogenesis of Fanconi anemia: an update.2017
- Author(s)
  Minoru Takata
- Organizer
  International Conference on “ Revolution of Laboratory Medicine In Modern Biology”
- Place of Presentation
  Mumbai, India
- Year and Date
  2017-02-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Novel Fanconi anemia E3 ligase RFWD3 promotes removal of both RPA and RAD51 from DNA damage sites during ICL repair.2016
- Author(s)
  Shojiro Inano, Koichi Sato, Kerstin Knies, Yoko Katsuki, Shinichiro Nakada, Akifumi Takaori-Kondo, Masamicih Ishiai, Detlev Schindler, Hitoshi Kurumizaka, Minoru Takata.
- Organizer
  28th Annual Fanconi Anemia research frund Scientific Symposium.
- Place of Presentation
  Bellevue, WA USA
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Myelodysplastic syndrome and acute myeloid leukemia in Japanese Fanconi anemia patients.2016
- Author(s)
  Miharu Yabe, Tsuyoshi Morimoto, Akiko Fukumura, Keisuke Ohtsubo, Takashi Koike, Takashi Shimizu, Hiromitsu Takakura, Katsuyoshi Koh, Etsuro Ito, Seiji Kojima, Asuka Hira, Minoru Takata and Hiromasa Yabe.
- Organizer
  28th Annual Fanconi Anemia research frund Scientific Symposium.
- Place of Presentation
  Bellevue, WA USA
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] 相同組換えにおけるRPAおよびRAD51の動態制御はRFWD3によるユビキチン化に依存する2016
- Author(s)
  稲野将二郎、佐藤浩一、勝木陽子、石合正道、中田慎一郎、胡桃坂仁志、高田　穣
- Organizer
  第75回日本癌学会学術総会　シンポジウム
- Place of Presentation
  横浜市パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] A novel Fanconi anemia gene regulates ICL repair and homologous recombination.2016
- Author(s)
  Minoru Takata
- Organizer
  第58回日本小児血液・がん学会学術集会　シンポジウム
- Place of Presentation
  品川プリンスホテル　東京
- Year and Date
  2016-12-15
- Invited
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] 相同組換えにおけるＲＰＡ２のユビキチン化を介した分解2015
- Author(s)
  稲野将二郎、佐藤浩一、石合正道、勝木陽子、中田慎一郎、胡桃坂仁志、高田　穣
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.2015
- Author(s)
  A. Hira, K. Yoshida, K.Sato, Y. Shiraishi, K. Chiba, H. Tanaka, S. Miyano, A. Shimamoto, H.Tahara, E.Ito, S.Kojima, H. Kurumizaka, S.Ogawa, M.Takata, H.Yabe, M. Yabe
- Organizer
  The 27th Annual Fanconi anemia research fund Scientific Symposium.
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.2015
- Author(s)
  Hira, K. Yoshida, K.Sato, Y. Shiraishi, K. Chiba, H. Tanaka, S. Miyano, A. Shimamoto, H.Tahara, E.Ito, S.Kojima, H. Kurumizaka, S.Ogawa, M.Takata, H.Yabe, M. Yabe.
- Organizer
  27th Annual Fanconi anemia research fund Scientific Symposium.
- Place of Presentation
  Tronto, Canada
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] DNA damage and repair in Fanconi anemia2015
- Author(s)
  高田　穰
- Organizer
  第２回IFOM－京都大学合同シンポジウム
- Place of Presentation
  京都大学紫蘭会館稲森ホール
- Year and Date
  2015-10-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] DNA damage and repair in Fanconi anemia2015
- Author(s)
  Minoru Takata
- Organizer
  第２回IFOM－京都大学合同シンポジウム
- Place of Presentation
  京都大学紫蘭会館稲森ホール
- Year and Date
  2015-10-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] 複製ストレスによるFANCD2集積部位のゲノムワイド解析2015
- Author(s)
  石合正道、岩嵜航、高橋数冴、久郷和人、小田有沙、大木千夏、福井哲也、河合秀彦、山本卓、太田邦史、印南秀樹、高田穣
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] UBE2T/FANCT is a novel FA gene identified in Japanese Fanconi anemia patients.2015
- Author(s)
  Minoru Takata, Asuka Hira, Kenichi Yoshida, Koichi Sato, Akira Shimamoto, Hitoshi Kurumizaka, Seishi Ogawa, Hiromasa Yabe, and Miharu Yabe.
- Organizer
  The 16th Ataxia-Teleangiectasia Workshop.
- Place of Presentation
  Beijing, China
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] 相同組換えにおけるＲＰＡ２のユビキチン化を介した分解2015
- Author(s)
  稲野将二郎、佐藤浩一、石合正道、勝木陽子、中田慎一郎、胡桃坂仁志、高田　穣
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] 複製ストレスによるFANCD2集積部位のゲノムワイド解析2015
- Author(s)
  石合正道、岩嵜航、高橋数冴、久郷和人、小田有沙、大木千夏、福井哲也、河合秀彦、山本卓、太田邦史、印南秀樹、高田穣
- Organizer
  BMB2015 ワークショップ
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] UBE2T/FANCT is a novel FA gene identified in Japanese Fanconi anemia patients.2015
- Author(s)
  Minoru Takata, Asuka Hira, Kenichi Yoshida, Koichi Sato, Akira Shimamoto, Hitoshi Kurumizaka, Seishi Ogawa, Hiromasa Yabe, and Miharu Yabe.
- Organizer
  The 16th Ataxia-Teleangiectasia Workshop.
- Place of Presentation
  Beijing China
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] ファンコニ貧血と遺伝性乳がん卵巣がん：相同組換え欠損を基盤とした高発がん症候群2015
- Author(s)
  高田　穰
- Organizer
  第74回日本癌学会　学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] DNA damage and repair in Fanconi anemia2015
- Author(s)
  Minoru Takata
- Organizer
  第２回IFOM－京都大学合同シンポジウム
- Place of Presentation
  京都大学紫蘭会館稲森ホール
- Year and Date
  2015-10-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.2015
- Author(s)
  A. Hira, K. Yoshida, K.Sato, Y. Shiraishi, K. Chiba, H. Tanaka, S. Miyano, A. Shimamoto, H.Tahara, E.Ito, S.Kojima, H. Kurumizaka, S.Ogawa, M.Takata, H.Yabe, M. Yabe.
- Organizer
  The 27th Annual Fanconi anemia research fund Scientific Symposium.
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] 相同組換えにおけるＲＰＡ２のユビキチン化を介した分解2015
- Author(s)
  稲野将二郎、佐藤浩一、石合正道、勝木陽子、中田慎一郎、胡桃坂仁志、高田　穣
- Organizer
  BMB2015 ワークショップ
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] ファンコニ貧血と遺伝性乳がん卵巣がん：相同組換え欠損を基盤とした高発がん症候群2015
- Author(s)
  高田　穰
- Organizer
  第74回日本癌学会　学術総会　シンポ
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] 複製ストレスによるFANCD2集積部位のゲノムワイド解析2015
- Author(s)
  石合正道、岩嵜航、高橋数冴、久郷和人、小田有沙、大木千夏、福井哲也、河合秀彦、山本卓、太田邦史、印南秀樹、高田穣
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Identification of UBE2T as a novel Fanconi anemia gene.2015
- Author(s)
  Asuka Hira, Kenichi Yoshida, Koichi Sato, Akita Shimamoto, Hidetoshi Tahara, Hitoshi Kurumizaka, Seishi Ogawa, Minoru Takata, Hiromasa Yabe, Miharu Yabe.
- Organizer
  ICRR2015
- Place of Presentation
  京都国際会館
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] ファンコニ貧血と遺伝性乳がん卵巣がん：相同組換え欠損を基盤とした高発がん症候群2015
- Author(s)
  高田　穰
- Organizer
  第74回日本癌学会　学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Identification of UBE2T as a novel Fanconi anemia gene.2015
- Author(s)
  Asuka Hira, Kenichi Yoshida, Koichi Sato, Akita Shimamoto, Hidetoshi Tahara, Hitoshi Kurumizaka, Seishi Ogawa, Minoru Takata, Hiromasa Yabe, Miharu Yabe.
- Organizer
  ICRR2015
- Place of Presentation
  Kyoto 国際会館
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01738
[Presentation] Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.2015
- Author(s)
  A. Hira, K. Yoshida, K.Sato, Y. Shiraishi, K. Chiba, H. Tanaka, S. Miyano, A. Shimamoto, H.Tahara, E.Ito, S.Kojima, H. Kurumizaka, S.Ogawa, M.Takata, H.Yabe, M. Yabe.
- Organizer
  The 16th Ataxia-Teleangiectasia Workshop.
- Place of Presentation
  Beijing, China
- Year and Date
  2015-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] Identification of UBE2T as a novel Fanconi anemia gene.2015
- Author(s)
  Asuka Hira, Kenichi Yoshida, Koichi Sato, Akita Shimamoto, Hidetoshi Tahara, Hitoshi Kurumizaka, Seishi Ogawa, Minoru Takata, Hiromasa Yabe, Miharu Yabe.
- Organizer
  ICRR2015
- Place of Presentation
  京都国際会館
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene.2014
- Author(s)
  Minoru Takata
- Organizer
  日米修復会議
- Place of Presentation
  エクシブ鳴門
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] 遺伝性DNA修復異常疾患：家族性乳がんとファンコニ貧血2014
- Author(s)
  高田　穣
- Organizer
  日本家族性腫瘍学会　第１７回家族性腫瘍セミナー
- Place of Presentation
  近畿大学・東大阪キャンパス
- Year and Date
  2014-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] 遺伝性DNA修復異常疾患：家族性乳がんとファンコニ貧血2014
- Author(s)
  高田　穣
- Organizer
  日本家族性腫瘍学会　第１７回家族性腫瘍セミナー
- Place of Presentation
  近畿大学・東大阪キャンパス
- Year and Date
  2014-08-24
- Invited
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene2014
- Author(s)
  Minoru Takata
- Organizer
  日米修復会議
- Place of Presentation
  エクシブ鳴門
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene.2014
- Author(s)
  Minoru Takata.
- Organizer
  日米修復会議
- Place of Presentation
  エクシブ鳴門
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] FANCD2 in chromatin anchors CtIP and regulates DNA end resection during crosslink repair.2013
- Author(s)
  J. Unno, A. Itaya, M. Taoka, K. Sato, J. Tomida, W. Sakai, T. Ikura, T. Isobe, H. Kurumizaka, M. Takata
- Organizer
  25th Annual Fanconi anemia research fund Scientific Symposium
- Place of Presentation
  Houston, Texas, USA
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] プログレス教育講演　　「ファンコニ貧血とＤＮＡクロスリンク修復の分子機構　ー最近の進歩ー」2013
- Author(s)
  高田　穣
- Organizer
  日本血液学会
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] FANCD2 in chromatin anchors CtIP and regulates DNA end resection during crosslink repair2013
- Author(s)
  J. Unno, A. Itaya, M. Taoka, K. Sato, J. Tomida, W. Sakai, T. Ikura, T. Isobe, H. Kurumizaka, M. Takata
- Organizer
  25th Annual Fanconi anemia research fund Scientific Symposium
- Place of Presentation
  Houston, Texas, USA
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] ファンコニ貧血とＤＮＡクロスリンク修復の分子機構　ー最近の進歩ー2013
- Author(s)
  高田　穣
- Organizer
  日本血液学会
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans”2012
- Author(s)
  Minoru Takata, Asuka Hira1, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  28th RBC-NIRS INTERNATIONAL SYMPOSIUM
- Place of Presentation
  コープイン京都（京都府）
- Invited
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] “Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans”2012
- Author(s)
  Minoru Takata, Asuka Hira, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  The 8th 3R Symposium
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Year and Date
  2012-11-25
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] 「DNA損傷への応答メカニズムと疾患」2012
- Author(s)
  高田穣
- Organizer
  第11回分子予防環境医学研究会(招待講演)
- Place of Presentation
  倉敷市市民会館（倉敷市）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] “Crosstalk signaling between checkpoint and the Fanconi anemia DNA repair pathway”2012
- Author(s)
  Junya Unno, Junya Tomida, Tomoko Shigechi, Akiko Itaya, and Minoru Takata
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌・ホテルさっぽろ芸文館・札幌市教育文化会館（北海道）
- Year and Date
  2012-09-19
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] DNA損傷シグナルとファンコニ貧血経路2012
- Author(s)
  高田穣
- Organizer
  生体調節研究所セミナー
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] "Fanconi anemia and the DNA damage response"2012
- Author(s)
  Minoru Takata
- Organizer
  The Sugahara Memorial International Symposium(招待講演)
- Place of Presentation
  稲盛ホール（京都市）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Crosstalk signaling between checkpoint and the Fanconi anemia DNA repair pathway2012
- Author(s)
  Junya Unno, Junya Tomida, Tomoko Shigechi, Akiko l taya, and Minoru Takata
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌・ホテルさっぽろ芸文館・札幌市教育文化会館(北海道)
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] Molecular pathogenesis of Fanconi anemia2012
- Author(s)
  Minoru Takata
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2012-12-01
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Genetic interplay betweenthe Fanconi anemia pathway and aldehyde metabolism in humans2012
- Author(s)
  Minoru Takata, Asuka Hira, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  The 8th3R Symposium
- Place of Presentation
  淡路市
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans2012
- Author(s)
  Minoru Takata, Asuka Hira1, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  28th RBC-NIRS INTERNATIONAL SYMPOSIUM
- Place of Presentation
  コープイン京都（京都府）
- Year and Date
  2012-11-29
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans2012
- Author(s)
  Minoru Takata, Asuka Hiral, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  28th RBC-NIRS INTERNATIONAL SYMPOSIUM
- Place of Presentation
  コープイン京都(京都府)
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] DNA損傷への応答メカニズムと疾患2012
- Author(s)
  高田穣
- Organizer
  第11回分子予防環境医学研究会
- Place of Presentation
  倉敷市市民会館(倉敷市)(招待講演)
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Fanconi anemia and the DNA damage response2012
- Author(s)
  Minoru Takata
- Organizer
  The Sugahara Memorial International Symposium
- Place of Presentation
  稲盛ホール(京都市)(招待講演)
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Molecular pathogenesis of Fanconi anemia2012
- Author(s)
  Minoru Takata
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] DNA損傷への応答メカニズムと疾患2012
- Author(s)
  高田穣
- Organizer
  第ll回分子予防環境医学研究会シンポジウムオーガナイザー & 演者
- Place of Presentation
  倉敷市
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans2012
- Author(s)
  Minoru Takata, Asuka Hira, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  The 8th 3R Symposium
- Place of Presentation
  淡路夢舞台国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] Fanconi anemia and the DNA damage response2012
- Author(s)
  Minoru Takata
- Organizer
  The Sugahara Memorial International Symposium
- Place of Presentation
  稲盛ホール(京都市)(招待講演)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans”2012
- Author(s)
  Minoru Takata, Asuka Hira, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  The 8th 3R Symposium
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Invited
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] DNA損傷への応答メカニズムと疾患2012
- Author(s)
  高田穣
- Organizer
  第11回分子予防環境医学研究会
- Place of Presentation
  倉敷市市民会館(倉敷市)(招待講演)
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Genetic interplay betweenthe Fanconi anemia pathway and aldehyde metabolism in humans2012
- Author(s)
  Minoru Takata, Asuka Hira, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  28th RBC-NIRS INTERNATIONAL SYMPOSIUM
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Molecular pathogenesis of Fanconi anemia2012
- Author(s)
  Minoru Takata
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Invited
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] The Sugahara Memorial International Symposium on Prospective Topics and Charm of Radiation Biology2012
- Author(s)
  Minoru Takata
- Organizer
  Fanconi anemia and the DNA damage response
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Crosstalk signaling between checkpoint and the Fanconi anemia DNA repair pathway2012
- Author(s)
  Junya Unno, Junya Tomida, Tomoko Shigechi, Akiko Itaya, and Minoru Takata
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌・ホテルさっぽろ芸文館・札幌市教育文化会館（北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Molecular pathogenesis of Fanconi anemia2012
- Author(s)
  Minoru Takata
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] DNA損傷応答シグナルにおけるクロマチン動態とエピジェネティクス制御2011
- Author(s)
  Minoru Takata
- Organizer
  27th RBC-NIRS International Symposium
- Place of Presentation
  コープイン京都(京都市)(招待講演)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 「放射線被曝医療」司会2011
- Author(s)
  高田穣
- Organizer
  第28回日本医学会総会　講演会　特別企画プログラム(招待講演)
- Place of Presentation
  東京ビッグサイト（東京都）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Histone chaperone activity of the FANCD2-FANCI complex and its importance in repair of interstrand DNA crosslinks by the Fanconi anemia pathway2011
- Author(s)
  oichi Sato, Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Tachiwana, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 複製ストレスによるファンコニ貧血経路の活性化には、ATR-ATRIPキナーゼ複合体が必須である2011
- Author(s)
  茂地智子、冨田純也、佐藤浩一、小林昌彦、内田恵美、山本健一、胡桃坂仁志、前原善彦、高田穣
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] International session for DNA repair and related subjects2011
- Author(s)
  Takata, M
- Organizer
  日本放射線影響学会第54回大会(招待講演)
- Place of Presentation
  神戸商工会議所会館（神戸市）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Homologous recombinational repair and Chk1-mediated S-phase arrest protect cells from 5-FU cytotoxicity repair and Chkl-mediated S-phase arrest protect cells from2011
- Author(s)
  Hiroyuki Kitao, Yoshihiko Fujinaka, Kazuaki Matsuoka, Makoto Iimori, Munkhbold Tuul, Ryo Sakasai, Ken-ichi Yamamoto, Minoru Takata, Yoshihiko Kakeji, Yoshihiko Maehara
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Genome Dynamics : molecular network in maintenance and conversion2011
- Author(s)
  高田穣
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  パシフィコ横浜(横浜市)(招待講演)
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] ファンコニ貧血蛋白質FANCD2/FANCI結合タンパク質のプロテオーム解析2011
- Author(s)
  海野純也、板谷(内田)亜希子、冨田純也、井倉毅、高田穣
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] ファンコニ貧血コア複合体によるATR-ATRIPキナーゼのクロマチン動態制御2011
- Author(s)
  高田穣、冨田純也、板谷(内田)亜希子、茂地智子、海野純也、前原善彦、石合正道
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] ファンコニ貧血とDNA損傷シグナリン」ポジウム[Internationa session for DNA repair and related subjects2011
- Author(s)
  Takata, M
- Organizer
  H放射線影響学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] ATR-ATRIP kinase complex is responsible for triggering of the FA pathway2011
- Author(s)
  Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John Eykelenboom, Pessina Fabio, Zhang Yanbin, Emi Uchida, Masamichi Ishiai, Noel Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata
- Organizer
  日本生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Fanconi anemia and the DNA damage signaling2011
- Author(s)
  Minoru Takata
- Organizer
  7th RBC-NIRS International Symposium
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] ファンコニ貧血コア複合体によるATR-ATRIPキナーゼのクロマチン動態制御2011
- Author(s)
  高田穣、冨田純也、板谷(内田)亜希子、茂地智子、海野純也、前原善彦、石合正道
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] An Absolute Requirement of ATRIP-ATR Kinase in Replication stress-induced Triggering of the FA Pathway Activation2011
- Author(s)
  T.Shigechi, J.Tomida, K.Sato, Y.Zhang, E.Uchida, J.Eykelenbo, N.Lowndes, H.Kurumizaka, Y.Maehara, M.Takata
- Organizer
  23rd ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM
- Place of Presentation
  Princesa Sofia Hotel(スペイン)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] リン酸化プロテオミクスを用いた新規DNA損傷初期応答キナーゼの探索2011
- Author(s)
  足立淳、鳴海良平、佐野聖三、久家貴寿、白水崇、松本雅記、中山敬一、井倉正枝、井倉毅、高田穣、朝長毅
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Molecular mechanisms of the Fanconi anemia pathway.2011
- Author(s)
  Masamichi Ishiai, Junya Tomida, Tomoko Shigechi, Akiko Itaya, Emi Uchida, Junya Unno, Minoru Takata
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] ファンコニ貧血DNA修復経路の中心タンパク質FANCD2はヌクレオソームアセンブリー活性を示す2011
- Author(s)
  石合正道、佐藤浩一、高田穣、胡桃坂仁志
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 特別企画プログラム東京ビッグサイト2011
- Author(s)
  高田穣
- Organizer
  第28回日本医学会総会
- Place of Presentation
  東京
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 複製ストレスによるFA経路の活性化には、ATRIP-ATRキナーゼが必須である2011
- Author(s)
  茂地智子、冨田純也、佐藤浩一、海野純也、小林昌彦、山本健一、石合正道、胡桃坂仁志、前原善彦、高田穣
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  古屋市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Molecular mechanisms of the Fanconi anemia pathway2011
- Author(s)
  Masamichi Ishiai, Junya Tomida, Tomoko Shigechi, Akiko Itaya, Emi Uchida, Junya Unno, Minoru Takata
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] An Absolute Requirement of ATRIP-ATR Kinase in Replication Stress-induced Triggering of the FA Pathway Activation2011
- Author(s)
  T.Shigechi, J.Tomida, K.Sato, Y.Zhang, E.Uchida, J.Eykelenbo, N.Lowndes, H.Kurumizaka, Y.Maehara, M.Takata
- Organizer
  23rd　ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM
- Place of Presentation
  Princesa Sofia Hotel（スペイン）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] 放射線被曝医療2011
- Author(s)
  高田穣
- Organizer
  第28回日本医学会総会講演会特別企画プログラム
- Place of Presentation
  東京ビッグサイト(東京都)(招待講演)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] 放射線被曝医療2011
- Author(s)
  高田穣
- Organizer
  第28回日本医学会総会講演会特別企画プログラム
- Place of Presentation
  東京ビッグサイト(東京都)(招待講演)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] ファンコニ貧血コア複合体によるATR-ATRIPキナーゼのクロマチン動態制御2011
- Author(s)
  高田穣、冨田純也、板谷(内田)亜希子、茂地智子、海野純也、前原善彦、石合正道
- Organizer
  第70回日本癌学会学術総会シンポジウム
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] ファンコニ貧血コア複合体によるＡＴＲ－ＡＴＲＩＰキナーゼのクロマチン動態制御2011
- Author(s)
  高田穣、冨田純也、板谷（内田）亜希子、茂地智子、海野純也、前原善彦、石合正道
- Organizer
  第70回日本癌学会学術総会　シンポジウム"Molecular basis of genome instability in cancer"
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] "Genome Dynamics: molecular network in maintenance and conversion" organizer2011
- Author(s)
  高田　穣
- Organizer
  日本分子生物学会第34回年会(招待講演)
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Mass spectrometric analysis identifiles factors associated with the Fanconi anemia proteins FANCD2 and FANCI2011
- Author(s)
  unya Unno, Akiko Itaya, Junya Tomida, Tsuyoshi Ikura, Minoru Takata
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Robust stimulation of the FANCD2 monoubiquitination by three-way brached DNAs2011
- Author(s)
  Kazue Toda, Koichi Sato, Masamichi Ishiai, Minoru Takata, Hitoshi Kurumizaka
- Organizer
  日本生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] DNA損傷応答シグナルにおけるクロマチン動態とエピジェネティクス制御2011
- Author(s)
  Minoru Takata
- Organizer
  27th RBC-NIRS International Symposium
- Place of Presentation
  コープイン京都(京都市)(招待講演)
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] International session for DNA repair and related subjects2011
- Author(s)
  Takata, M
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸商工会議所会館(神戸市)(招待講演)
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Molecular mechanisms of the Fanconi anemia pathway2011
- Author(s)
  Masamichi Ishiai, Junya Tomida, Tomoko Shigechi, Akiko Itaya, Emi Uchida, Junya Unno, Minoru Takata
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] An Absolute Requirement of ATRIP-ATR Kinase in Replication Stress-induced Triggering of the FA Pathway Activation2011
- Author(s)
  T. Shigechi, J. Tomida, K. Sato, Y. Zhang, E. Uchida, J. Eykelenbo, N. Lowndes, H. Kurumizaka, Y. Maehara, M. Takata
- Organizer
  23rd ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 「ファンコニ貧血とDNA損傷シグナリング」シンポジウム「International session for DNA repair and related subjects」2011
- Author(s)
  Takata,M
- Organizer
  日本放射線影響学会第54回大会招待講演
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Genome Dynamics : molecular network in maintenance and conversion:molecularnetworkinmaintenanceandconversion2011
- Author(s)
  高田穣
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Inhibition of NHEJ Reveals Distinct Roles for FANCG in the Repair of Interstrand Crosslinks and DNA Strand Breaks2011
- Author(s)
  J. B. Wilson, J. K. Lingley, F. A. Makki, A. M. Alandwani, K. Lee, Y. Xiao, M. Takata, G. M. Kupfer, N. J. Jones
- Organizer
  23rd ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Fanconi anemia and the DNA damage signaling2011
- Author(s)
  Minoru Takata
- Organizer
  DNA損傷応答シグナルにおけるクロマチン動態とエピジェネティクス制御, 27th RBC-NIRS International Symposium(招待講演)
- Place of Presentation
  コープイン京都（京都市）
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] ファンコニ貧血蛋白FANCD2によるNF-kappaB転写制御機構の解析2011
- Author(s)
  松下暢子、菊間啓太、太田莉英子、もたい龍介、徳山郷±、高田穣、胡桃坂仁志、山下孝之、稲留涼子、柳茂
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] International session for DNA repair and related subjects2011
- Author(s)
  Takata, M
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸商工会議所会館(神戸市)(招待講演)
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Genome Dynamics : molecular network in maintenance and conversion2011
- Author(s)
  高田穣
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  パシフィコ横浜(横浜市)(招待講演)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] An Absolute Requirement of ATRIP-ATR Kinase in Replication Stress-induced Triggering of the FA Pathway Activation2011
- Author(s)
  T.Shigechi, J.Tomida, K.Sato, Y.Zhang, E.Uchida, J.Eykelenbo, N.Lowndes, H.Kurumizaka, Y.Maehara, M.Takata
- Organizer
  23rd ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM
- Place of Presentation
  Princesa Sofia Hotel(スペイン)
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Fanconi貧血原因遺伝子餌艦η2及びE郡01一の機能解析2011
- Author(s)
  佐藤浩一, 石合正道, 戸田和江, 古越聡, 越坂部晃永, 立和名博昭, 堂前直, 小布施力史, 木村宏, 高田穣, 胡桃坂仁志
- Organizer
  第9回核ダイナミクス研究会
- Place of Presentation
  伊豆市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Molecular mechanisms of the Fanconi anemia pathway2011
- Author(s)
  Masamicni Ishiai, Junya Tomida, Tomoko Shigechi, Akiko Itaya, Emi Uchida, Junya Unno, Minoru Takata
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] ファンコニ貧血コア複合体によるATR-ATRIPキナーゼのクロマチン動態制御2011
- Author(s)
  高田穣、冨田純也、板谷(内田)亜希子、茂地智子、海野純也、前原善彦、石合正道
- Organizer
  第70回日本癌学会学術総会シンポジウム"Molecular basis of genome instability in cancer"
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23651046
[Presentation] Mcm8 and Mcm9 form a novel complex involved in resistance to DNA crosslinking agents2011
- Author(s)
  Kohei Nishimura, Masamichi Ishiai, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato Kanemaki
- Organizer
  日本生物学会第34回年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Activation mechanisms of the Fanconi anemia pathway2010
- Author(s)
  Takata M.
- Organizer
  Preventing genomic instability, neoplasia and premature ageing emerging role of the Fanconi anemia-BRCA caretaker network. Traute Schroeder-Kurth Symposium.
- Place of Presentation
  Wurburg, Germany
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] Artemisの核内動態制御機構の解析2010
- Author(s)
  石合正道、島弘季、田代聡、高田穣
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  ワークショップ京都市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] The DT40 cell line as a model genetic system2010
- Author(s)
  Takata M.
- Organizer
  EMBO Practical Course
- Place of Presentation
  Galway, Ireland(招待講演)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] DNA損傷応答におけるファンコニ貧血経路の活性化メカニズム2010
- Author(s)
  冨田純也、板谷亜希子、内田恵美、茂地智子、井倉正枝、胡桃坂仁志、井倉毅、石合正道、高田穣
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  ワークショップ京都
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Gene targeting : vector design and construction EMBO practical course2010
- Author(s)
  Minoru Takata
- Organizer
  EMBO practical course
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] リン酸化・モノユビキチン化によるファンコニ貧血・DNA修復経路の活性化メカニズム2010
- Author(s)
  石合正道, 冨田純也, 茂地智子, 板谷亜希子, 高田穣
- Organizer
  第9回核ダイナミクス研究会
- Place of Presentation
  伊豆市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 発がんとDNA損傷応答の分子メカニズム2010
- Author(s)
  高田穣
- Organizer
  肺がん分子病態研究会
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Activation mechanisms of the Fanconi anemia pathway2010
- Author(s)
  Takata M.
- Organizer
  Preventing genomic instability, neoplasia and premature ageing emerging role of the Fanconi anemia- BRCA caretaker network.Traute Schroeder-Kurth Symposium.
- Place of Presentation
  Wurburg, Germany(招待講演)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] Activation mechanisms of the Fanconi anemia pathway via ATR signaling2010
- Author(s)
  高田穣
- Organizer
  放射線生物若手の会(原子炉実験所
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] The DT40 cell line as a model genetic system2010
- Author(s)
  Takata M.
- Organizer
  EMBO Practical Course
- Place of Presentation
  Galway, Ireland
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] Activation mechanisms of the Fanconi anemia pathway2010
- Author(s)
  Minoru Takata
- Organizer
  Traute Schroeder-Kurth Symposium at the University of Wu rzburg
- Place of Presentation
  Gemmany
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 発がんとDNA損傷応答の分子メカニズム2010
- Author(s)
  高田穣
- Organizer
  肺がん分子病態研究会
- Place of Presentation
  東京
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] DNAダメージにおけるArtemisの核内動態制御2010
- Author(s)
  石合正道、島弘季、田代聡、高田穣
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] FAAP20 is Required for Normal Activation of the Fanconi Anemia-associated DNA Damage Response Pathway2010
- Author(s)
  Z. Yan, R. Guo, W. Shen, D. FoxIII, A. B. Oostra, M. Takata, D. Schindler, H. oatlin, J. de Winter, W. Wang.
- Organizer
  22nd Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Minnesota(USA)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] FANCI phosphorylation by ATR kinase proceeds in a Rad17/TopBP1-independent manner2010
- Author(s)
  Junya Tomida, Akiko Itaya, Emi Uchida, Tomoko Shigechi, Masahiko Kobayashi, Ken-ichi Yamamoto, Masae Ikura, Tsuyoshi Ikura, Agata Smogorzewska, Masamichi Ishiai, Minoru Takata
- Organizer
  第33回年会日本生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] How we can achieve disruption of the genes essential for cell viability in DT40 cells?2010
- Author(s)
  Minoru Takata
- Organizer
  EMBO practical course
- Place of Presentation
  Ireland
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] FANCG Functions Independently of the FA Core Complex in Homologous Recombination Repair of Phleomycin-induced DNA Damage2010
- Author(s)
  N. J. Jones, A. Aladwani, Y. Xiao, V. S. Mysore, G. M. Kupfer, M. Takata, J. B. Wilson
- Organizer
  22nd Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Minnesota(USA)
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] REGULATION OF CROSS-LINK REPAIR THROUGH THE FANCONI ANEMIA PATHWAY.2009
- Author(s)
  Minoru Takata, Junya Tomida, Akiko Itaya, Tomoko Shigechi, Masamichi Ishiai
- Organizer
  The Fortieth International Symposium of the Princess Takamatsu Cancer Research Fund
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway2009
- Author(s)
  Minoru Takata, Junya Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itaya, Masamichi Ishiai
- Organizer
  Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Baltimore, MA, USA
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 高発がん遺伝病ファンコニ貧血の分子メカニズム, 小児血液腫瘍の発症リスクと先天異常2009
- Author(s)
  高田穣
- Organizer
  第71回日本血液学会学術集会シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] REGULATION OF CROSS-LINK REPAIR THROUGH THE FANCONI ANEMIA PATHWAY2009
- Author(s)
  Minoru Takata, Junya Tomida, Akiko Itaya, Tomoko Shigechi, Masamichi Ishiai
- Organizer
  The Fortieth International Symposium of the Princess Takamatsu Cancer Research Fund
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] DNA damage response and hematological disorder, DNA damage signaling in the Fanconi anemia pathogenesis2009
- Author(s)
  Takata M.
- Organizer
  第51回小児血液学会シンポジウム
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] 高発がん遺伝病ファンコニ貧血の分子メカニズム2009
- Author(s)
  高田穣
- Organizer
  第71回日本血液学会学術集会シンポジウム「小児血液腫瘍の発症リスクと先天異常」
- Place of Presentation
  京都市国際会館
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] 高発がん遺伝病ファンコニ貧血の分子メカニズム2009
- Author(s)
  高田穣
- Organizer
  第71回日本血液学会学術集会シンポジウム「小児血液腫瘍の発症リスクと先天異常」
- Place of Presentation
  京都市国際会館
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] DNA damage signaling in the Fanconi anemia pathogenesis2009
- Author(s)
  高田穣
- Organizer
  第51回小児血液学会血液プレジデンシャルシンポジウム「DNA damage response and hematological disorder」
- Place of Presentation
  千葉東京ベイホテル東急
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] DNA damage signaling in the Fanconi anemia pathogenesis2009
- Author(s)
  Minoru Takata
- Organizer
  第51回小児血液学会血液プレジデンシャルシンポジウム「DNA damage response and hematological disorder」
- Place of Presentation
  千葉東京ベイホテル東急
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] REGULATION OF CROSS-LINK REPAIR THROUGH THE FANCONI ANEMIA PATH WAY2009
- Author(s)
  Minoru Takata, Junya Tomida, Akiko Itaya, Tomoko Shigechi, Masamichi Ishiai
- Organizer
  The Fortieth International Symposium of the Princess Takamatsu Cancer Research Fund
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] Regulation Of Cross-Link Repair Through The Fanconi Anemia Pathway.2009
- Author(s)
  Takata M., Tomida J., Itaya A., Shigechi T., Ishiai M.
- Organizer
  高松宮がん研究基金シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] DNA damage signaling in the Fanconi anemia pathogenesis2009
- Author(s)
  高田穣
- Organizer
  第51回小児血液学会血液プレジデンシャルシンポジウム「DNA damage response and hemato logical disorder」
- Place of Presentation
  千葉東京ベイホテル東急
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway2009
- Author(s)
  Minom Takata, Junva Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itava, Masamichi Ishiai
- Organizer
  Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium
- Data Source
  KAKENHI-PROJECT-21390094
[Presentation] 高発がん遺伝病ファンコニ貧血の分子メカニズム2009
- Author(s)
  高田穣
- Organizer
  第71回日本血液学会学術集会シンポジウム「小児血液腫瘍の発症リスクと先天異常」
- Place of Presentation
  京都市国際会館
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway2009
- Author(s)
  Minoru Takata, Junya Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itaya, Masamichi Ishiai
- Organizer
  Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Baltimore, MA, USA
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] Monoubiquitination and phosphorylation dependent activation of the Fanconi anemia pathway, Recent Development in DNA Repair Studies2009
- Author(s)
  Minoru Takata
- Organizer
  The 3rd International Open Laboratory Workshop
- Place of Presentation
  放射線総合医学研究所千葉県
- Year and Date
  2009-02-27
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway.2009
- Author(s)
  Minoru Takata, Junya Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itaya, Masamichilshiai
- Organizer
  Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Baltimore, MA, USA
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] 「ファンコニ貧血経路によるゲノム安定化メカニズム」「生き物はどのようにして放射線に立ち向かうか-DNA損傷応答と適応応答-」2008
- Author(s)
  高田穣(招待講演)
- Organizer
  第3回放射線防護研究センターシンポジウム(放射線総合医学研究所)
- Place of Presentation
  千葉県
- Year and Date
  2008-12-16
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] ファンコニ貧血経路の制御とFANCI タンパク質のリン酸化メカニズム2008
- Author(s)
  冨田純也、内田亜希子、北尾洋之、木下英司、内田恵美、小林昌彦、山本健一、小池透、石合正道、高田穣
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Role of FANCI protein and its phosphorylation for the Fanconi anemia pathway function2008
- Author(s)
  M. Takata, H. Kitao, A. kinomura, A. Smogorzewska, S. J. Elledge, M. Ishiai
- Organizer
  Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Chemopreventive effect of gefitinib on tumorgenesis in smoking unrelated lung cancer mouse model AACR Annual Meeting 20082008
- Author(s)
  Ohashi K, Kiura K, Osawa M, Takeda H, Kubo T, Ichihara E, Takigawa N, Hirano S, Tanimoto M, Takata M
- Organizer
  米国癌学会総会, ミニシンポジウム
- Place of Presentation
  San Diego, CA Abstract # 4186 Minisymposium
- Data Source
  KAKENHI-PROJECT-19590895
[Presentation] ゲノムの安定性維持メカニズムとファンコニ貧血2008
- Author(s)
  高田穣
- Organizer
  第101回小児血液腫瘍懇話会
- Place of Presentation
  東京都
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] ファンコニ貧血経路の活性化制御とFANCIタンパク質のリン酸化メカニズム2008
- Author(s)
  冨田純也、内田亜希子、北尾洋之、木下英司、内田恵美、小林昌彦、山本健一、小池透、石合正道、高田穣
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] フアンコニ貧血経路によるゲノム安定化メカニズム2008
- Author(s)
  高田穣
- Organizer
  第3回放射線防護研究センターシンポジウム
- Place of Presentation
  千葉県放射線総合医学研究所
- Year and Date
  2008-12-16
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Symposium "DNA repair network deficiency and carcinogenesis".2008
- Author(s)
  Ishiai M., Kitao H., Takata M.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Faneoni anemia pathway. Symposium2008
- Author(s)
  Ishiai M, Kitao H, Takata M
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-20651014
[Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Symposium : "DNA repair network deficiency and carcinogenesis"2008
- Author(s)
  Ishiai M, Kitao H, Takata M.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市, 神戸
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Frequent Loss of the Immunogolobulin Heavy Chain Gene Occurs in FANCJ deficient DT40 Cell Line2008
- Author(s)
  H. Kitao, I. Nada, A. Kinomura, M. Takata
- Organizer
  Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway Symposium.2008
- Author(s)
  Ishiai M, Kitao H, Takata M
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] ゲノムの安定性維持メカニズムとファンコニ貧血2008
- Author(s)
  高田穣
- Organizer
  第1 0 1回小児血液腫瘍懇話会
- Place of Presentation
  東京・経団連会館
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] FANCI phosphorylation functions as a-molecular switch toturn on the Fanconi anemia pathway. Symposium2008
- Author(s)
  Ishiai M, Kitao H, Takata M
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] ファンコニ貧血経路によるゲノム安定化メカニズム2008
- Author(s)
  高田穣
- Organizer
  第3回放射線防護研究センターシンポジウム
- Place of Presentation
  千葉県放射線総合医学研究所
- Year and Date
  2008-12-16
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Role of Fanci protein and its phosphorylation for the Fanconiaanemia pathway function2007
- Author(s)
  Minoru Takata
- Organizer
  Nineteenth Annual Fanconia Anemia Research Fund Sceintific Symposium
- Place of Presentation
  The Westin Michigan Avenue, Chicago,II, USA
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] ファンコニ貧血コア複合体によるFANCD2/FANCI複合体のモノユビキチン化と相同組換え修復。ワークショップ放射線DNA損傷修復機構研究の最前線2007
- Author(s)
  高田穣、北尾洋之、木野村愛子、石合正道
- Organizer
  放射線影響学会6第50回大会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] FANCJ 遺伝子欠損DT40細胞株で起こる免疫グロブリン重鎖遺伝子でのゲノム欠失2007
- Author(s)
  北尾洋之、ナンダインドラジット、木野村愛子、シュミットマイケル、高田穣
- Organizer
  ワークショップ第30回分子生物学会第80回日本生化学会合同大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] FancD2/FancI complex regulates crosslink repair in the Fanconi anemia pathway. "Chromosome and Genome Stability and Instability"2007
- Author(s)
  M.Takata
- Organizer
  Chromosome Cycle International Symposium
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Chromosome and Genome Stability and FancD2/FancI complex regulates crosslink repair in the Fanconi anemia pathway. Instability2007
- Author(s)
  Takata M.
- Organizer
  Chromosome Cycle International Symposium
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] Role of Fanci protein and its phosphorylation for the Fanconia anemia pathway function2007
- Author(s)
  Minoru Takata
- Organizer
  Nineteenth Annual Fanconia Anemia Research Fund Sceintific Symposium
- Place of Presentation
  The westin Michigan Avenue, Chicago, Il, U.S.A
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Transgenic mice with mouse EGFR mutation developed lung adenocarcinoma.2007
- Author(s)
  Ohashi K, Rai K, Kiura K, Osawa M, Hirano S, Fujiwara Y, Yoshino T, Takigawa N, Takata M, Tanimoto M
- Organizer
  2007 AACR Annual Meeting 米国癌学会
- Place of Presentation
  Los Angeles, CA, 米国
- Year and Date
  2007-04-17
- Data Source
  KAKENHI-PROJECT-19590895
[Presentation] ファンコニ貧血コア複合体によるモノユビキチン化とDNAクロスリンク修復制御2007
- Author(s)
  高田穣、北尾洋之、木野村愛子、石合正道
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Functional Pathways in Recombinational Repair.2007
- Author(s)
  Takata M.
- Organizer
  Keystone Symposia "Genome Instability and Repair" Breckenridge
- Place of Presentation
  CO, USA.
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] Fanconi貧血とゲノム不安定性
- Author(s)
  高田　穣
- Organizer
  第13回血液フォーラム21　－造血不全－
- Place of Presentation
  東京フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] Fanconi貧血とゲノム不安定性
- Author(s)
  高田　穣
- Organizer
  第13回血液フォーラム21　－造血不全－
- Place of Presentation
  東京フォーラム
- Invited
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Infant Japanese Fanconi anemia patients with the ALDH2-AA genotype.
- Author(s)
  M. Yabe, A. Hira, H, Yabe, T. Morimoto, A. Fukumura, M. Miyashita, K. Ohtsubo, K. Matsuo, M. Takata.
- Organizer
  26th Annual Fanconi Anemia Research Fund Scientific Symposium.
- Place of Presentation
  Bethesda MA, USA
- Year and Date
  2014-09-18 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] 日本人ファンコニ貧血患者における新規原因遺伝子UBE2Tの同定
- Author(s)
  平明日香, 吉田健一, 佐藤浩一, 嶋本顕, 田原栄俊, 胡桃坂仁志, 小川誠司, 高田穣, 矢部普正, 矢部みはる
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] UBE2T is a novel FA gene identified in Japanese Fanconi anemia patients
- Author(s)
  Minoru Takata, Asuka Hira, Kenichi Yoshida, Koichi Sato, Akira Shimamoto, Hidetoshi Tahara, Hitoshi Kurumizaka, Seishi Ogawa, Hiromasa Yabe, and Miharu Yabe
- Organizer
  The 9th 3R Symposium,
- Place of Presentation
  Gotemba Kogen Hotel
- Year and Date
  2014-11-17 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] UBE2T is a novel FA gene identified in Japanese Fanconi anemia patients
- Author(s)
  Minoru Takata, Asuka Hira, Kenichi Yoshida, Koichi Sato, Akira Shimamoto, Hidetoshi Tahara, Hitoshi Kurumizaka, Seishi Ogawa, Hiromasa Yabe, and Miharu Yabe
- Organizer
  The 9th 3R Symposium
- Place of Presentation
  Gotemba Kogen Hotel
- Year and Date
  2014-11-17 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] 日本人ファンコニ貧血患者における新規原因遺伝子UBE2Tの同定
- Author(s)
  平明日香, 吉田健一, 佐藤浩一, 嶋本顕, 田原栄俊, 胡桃坂仁志, 小川誠司, 高田穣, 矢部普正, 矢部みはる
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26550026
[Presentation] 日本人ファンコニ貧血患者における新規原因遺伝子UBE2Tの同定
- Author(s)
  平明日香, 吉田健一, 佐藤浩一, 嶋本顕, 田原栄俊, 胡桃坂仁志, 小川誠司, 高田穣, 矢部普正, 矢部みはる
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  横浜市みなとみらいパシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] ファンコニ貧血経路とそのキータンパク質FANCD2の機能解析
- Author(s)
  高田穣, 勝木陽子, 佐藤浩一, 石合正道, 胡桃坂仁志
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] Infant Japanese Fanconi anemia patients with the ALDH2-AA genotype.
- Author(s)
  M. Yabe, A. Hira, H, Yabe, T. Morimoto, A. Fukumura, M. Miyashita, K. Ohtsubo, K. Matsuo, M. Takata.
- Organizer
  26th Annual Fanconi Anemia Research Fund Scientific Symposium.
- Place of Presentation
  Bethesda MA, USA
- Year and Date
  2014-09-18 – 2014-09-21
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] ファンコニ貧血経路とそのキータンパク質FANCD2の機能解析
- Author(s)
  高田穣, 勝木陽子, 佐藤浩一, 石合正道, 胡桃坂仁志
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  横浜市みなとみらいパシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] UBE2T is a novel FA gene identified in Japanese Fanconi anemia patients
- Author(s)
  Minoru Takata, Asuka Hira1, Naoya Suzuki, Akira Niwa, Tatsutoshi Nakahata, Hiromasa Yabe, Megumu K. Saito, Keitaro Matsuo, Miharu Yabe
- Organizer
  The 9th 3R Symposium
- Place of Presentation
  Gotemba Kogen Hotel
- Year and Date
  2014-11-17 – 2014-11-21
- Data Source
  KAKENHI-PLANNED-23114010
[Presentation] Infant Japanese Fanconi anemia patients with the ALDH2-AA genotype.
- Author(s)
  M. Yabe, A. Hira, H, Yabe, T. Morimoto, A. Fukumura, M. Miyashita, K. Ohtsubo, K. Matsuo, M. Takata.
- Organizer
  26th Annual Fanconi Anemia Research Fund Scientific Symposium.
- Place of Presentation
  Bethesda MA, USA
- Year and Date
  2014-09-18 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-24310042
[Presentation] ファンコニ貧血経路とそのキータンパク質FANCD2の機能解析
- Author(s)
  高田穣, 勝木陽子, 佐藤浩一, 石合正道, 胡桃坂仁志
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26550026

1. TAKEDA Shunichi (60188191)

# of Collaborated Projects: 14 results

# of Collaborated Products: 2 results
2. SONODA Eiichiro (50281093)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
3. IWAI Yuko (10281726)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
4. KIURA Katsuyuki (10243502)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
5. KITAO Hiroyuki (30368617)

# of Collaborated Projects: 5 results

# of Collaborated Products: 34 results
6. ISHIAI Masamichi (90298844)

# of Collaborated Projects: 4 results

# of Collaborated Products: 32 results
7. MATSUSHITA Nobuko (30333222)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
8. HIRANO Seiki (20368616)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
9. TAKIGAWA Nagio (60325107)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
10. TOMIDA Junya (50511367)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
11. YOSHINO Tadashi (70183704)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
12. KATSUKI Yoko (00645377)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
13. ICHIHARA Eiki (40549705)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
14. 原田実根 (00019621)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. YAGI Takashi (80182301)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 牟安峰 (20894455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
17. CIARAN Morri

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. ITAYA Akiko (50535812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
19. HOTTA Katsuyuki (70379816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKABEPPU Yusaku (30180350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NAKAMURA Eizo (80201672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. UNNO Junya (50614153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. NAKAYAMA Tatsuo (60031712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Hosokawa Hiroshi (90359779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Maegawa Shingo (30467401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Kobayashi Takehiko (40270475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. NAKAYAMA Jun-ichi (60373338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. OHTA Kunihiro (90211789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. INNAN Hideki (90444140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KAJIKAWA Masaki (90361766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. HISHIDA Takashi (60335388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. Masumoto Hiroshi (70229384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. KANOH Junko (10323809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 下田和哉 (90311844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 権藤久司 (10253428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 池田和真 (50176088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 品川克至 (00273988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 石丸文彦 (50284097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 平明日香 (30772777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
40. 山本和彦 (40333223)

# of Collaborated Projects: 1 results

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41. 藤森亮 (50314183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 佐藤浩一 (60708585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
43. 望月綾子 (80817148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
44. 大橋圭明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 頼冠明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 高田三郎

# of Collaborated Projects: 1 results

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47. 大澤昌宏

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 武田洋昌

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 藤井昌学

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 久保寿夫

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 柏原宏美

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 原田大二郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 越智宣昭

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. 八杉昌幸

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. HOEIJMAKAS J

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. THOMAS Lawre

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. MORRISON Cia

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. SAITOH Megumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. NAKADA Shinichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. MOTEGI Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
61. KANAO Rie

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. TANAKA Hideo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. ITO Hidemi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
64. Chiba Shigeru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
65. YABE Miharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
66. YABE Hiromasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
67. KATO Shunichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
68. 関政幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
69. 笹沼博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
70. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
71. 江藤浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
72. 原田浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
73. 小川勝洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
74. 田中恵太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
75. 田中祐吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
76. 田中勇悦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
77. 田原栄俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
78. 吉田稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
79. 河合秀彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
80. 胡桃坂仁志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takata Minoru 高田 穣

TAKATA Minoru 高田 穣

高田 穰 タカダ ユタ

Research Projects

Research Products

Co-Researchers

Genome-stabilizing activity of aldehyde catalyzing enzymes that support epigenetic reprogrammingPrincipal Investigator

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The role of SLFN11 gene that determines DNA damage sensitivity at the stalled replication forksPrincipal Investigator

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Hunting and analysis of novel genes causing Fanconi anemiaPrincipal Investigator

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Analysis of tissue-specific distribution and function of ALDH isoforms in Fanconi anemia pathwayPrincipal Investigator

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Regulatory mechanisms of CtIP nuclease during DNA crosslink repairPrincipal Investigator

Principal Investigator

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Analysis of disorders defective in the mechanisms for fork stabilizationPrincipal Investigator

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Basic and clinical study of EGFR gene mutation-positive lung cancer using a genetically modified mouse

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Regulation of protein expression using a cell cyclce-specific degron and its application to functional analysisPrincipal Investigator

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A basic studyon malignant mesothelioma pathogenesis by internal radiation exposure of radium contained in the iron-containing protein

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The function of non-coding DNA for genome integrity

Principal Investigator

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Regulation of the ubiquitin system by checkpoint kinases in response to stalled replication forksPrincipal Investigator

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ファンコニ貧血経路の真のターゲットは内因性ホルマリンによる蛋白質ゲノム架橋か?Principal Investigator

Principal Investigator

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Regulation of the ubiquitin system by checkpoint kinases in response to stalled replication forksPrincipal Investigator

Principal Investigator

Takata Minoru 高田穣

TAKATA Minoru 高田穣

高田穰タカダユタ