IWAI Yuko 岩井裕子

Researcher Number	10281726
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007: 京大, 生命科学研究科, 助教授 2001 – 2006: 京都大学, 生命科学研究科, 助教授 1999 – 2000: Kyoto Univ. Devision of integrated, 生命科学研究科, 助手 1999: 京都大学, 大学院・生命科学研究科, 助手 1999: 京都大学, 生命科学研究所, 助手 1997 – 1998: 京都大学, 医学研究科, 助手 1997: 京都大学, 大学院・医学研究科, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Functional biochemistry / Functional biochemistry / 環境影響評価(含放射線生物学) / 基礎ゲノム科学 / Pathological medical chemistry Except Principal Investigator Molecular biology / General medical chemistry
Keywords	Principal Investigator 出芽酵母 / 鉄代謝 / DT40 / 鉄 / 鉄-硫黄クラスター / 核外移行 / 転写制御 / MRE11 / 転写因子 / DT40細胞 … More / iron metabolism / mitochondria / ROS / ミトコンドリア / 相同DNA組み換え / 毛細血管拡張性失調症 / ナイミーヘン症 / 修復 / 染色体不安定性 / Saccharomyces cerevisiae / knock-out / iron-sulfur cluster / トリBリンパ細胞 / 鉄ー硫黄クラスター / 鉄-硫黄ラスター / ノックアウト / appotosis / thioredoxin / iron-sulfer cluster / 活性酸素種 / 鉄イオウクラスター / アポトーシス / チオレドキシン / 鉄-イオウクラスター / chromosomal aberrations / telomere / homologousre combination / Ataxia-telangiectasia-like disorder / Nijmegenbreakage syndrome / Ataxia telangiectasia / ネイミーヘン症 / 毛細血管拡張失調症 / 毛細血管拡張性失調症類似症 / 染色体異常 / テロメア / 毛細血管拡張性共調症類似症 / マイクロアレイ / アルカリフォスファターゼ / ゲノム / 亜鉛 / 金属 / 酸化 / サイクリン / リボヌクレオチド還元酵素 / 細胞増殖 / IRP2 / c-myc / GAL4 / 転写活性化ドメイン / DNA結合ドメイン / Importin / CRM1 / 核外輸送シグナル / AFT1 / 低分子量G蛋白質 / 核輸送担体 / 核移行シグナル / センシング / ヘム / 核内移行担体 / 細胞内局在 / 相互作用 / 核外移行担体 / 細胞内局 / 非相同DNA組み換え / 核移行 / 鉄センシング機構 / バンド・シフト法 / 鉄取り込み / 代謝 / 細胞内鉄濃度 / P-type ATPase / Menkes病 / Wilson病 / トランスポーター / 酸化ストレス / 金属イオン代謝 / チェックポイント / 細胞周期 / 翻訳調節 / 転写調節 / ストレス応答 / 金属代謝 / DNA2重鎖切断 / RAD54 / RAD52 / RAD51 / 相同DNA組換え … More Except Principal Investigator Rad51 / DT40 / DNA修復 / 放射線 / ターゲットインテグレーション / ヌクレオチド除去修復 / ジーンターゲティング / DNA相同組換え / 染色体断裂 / 標的組換え / 相同DNA組換え / DNA repair / DT40細胞 / 組み換え修復 / 相同組み換え / Rad 51 / Homologous DNA recombination / ionizing radiation / homologous DNA recombination / chemothrapy of cancer / checkpoint / fumorigenesis / Ku / 電離放射線 / 遺伝子ノックアウト / 標的組み換え / 相同DNA組み換え / チェックポイント / 癌治療 / 発がん / 姉妹染色分体交換 / 染色体不安定性 / Rad54 / Rad52 / 遺伝子相同組み換え / 染色体異常 / 誘導型ノックアウト / 相同組換え / 胸腺における選択 / アロ抗原 / 組織適合抗原 / T細胞抗原受容体 / MHC拘束性 / キラーT細胞 Less

鉄イオンによる転写制御機構の分子基盤Principal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
鉄イオンによる転写制御の分子基盤Principal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
金属代謝機構のゲノムワイド解析Principal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Kyoto University
Roles of mitochondria in iron metabolismPrincipal Investigator
- Principal Investigator
  
  IWAI Yuko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyoto University
Comprehensive study for mitochondrial iron metabolismPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Yuko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  KYOTO UNIVERSITY
細胞内鉄濃度を制御する転写因子の鉄センシング機構と転写活性化機構Principal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Myc癌遺伝子のターゲットとしての鉄代謝機構とその細胞増殖調節作用Principal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
細胞内鉄濃度を制御する転写因子の鉄センシング機構と転写活性化機構Principal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
DNA傷害の認識と修復・細胞周期停止へのシグナル伝達Principal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
高頻度に標的組換えを起すニワトリ細胞株を使った染色体構造維持構造の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
Maintenance of telomere structure by MRE11 associated with the Nijmegen breakage syndrome protein.Principal Investigator
- Principal Investigator
  
  IWAI Yuko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYOTO UNIVERSITY
高頻度にターゲットインテグレーションをおこすニワトリ細胞株の相同組換え機構の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
高頻度にターゲットインテグレーションを起すニワトリ細胞株の相同組換え機構の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
遺伝子ターゲッティングの組換え頻度の調節機構の解析-次世代の遺伝子治療への基礎的アプローチ-
- Principal Investigator
  
  園田英一朗
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  Kyoto University
Analysis of homologous DNA recombination using the chicken B-lymphocyte line
- Principal Investigator
  
  TAKEDA Shunichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Reverse Genetic Analysis of Homologous DNA Recombination in Higher Eukaryotes
- Principal Investigator
  
  TAKEDA Shunichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KYOTO UNIVERSITY
染色体安定性の癌化への関わり(DT40細胞を用いた試み)Principal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
RAD54変異ニワトリBリンパ細胞株の、DNA複製中に起ったDNA損傷の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ニワトリBリンパ細胞株での、RAD遺伝子群の、DNA組換えと、修復機能の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
MHCクラスIとクラスIIの両方の分子を認識できるT細胞のT細胞抗原受容体の解析
- Principal Investigator
  
  武田俊一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
鉄・銅代謝異常関連遺伝子の単離およびその疾患との関わりPrincipal Investigator
- Principal Investigator
  
  岩井裕子
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
遺伝子ターゲッティングの組換え頻度を調節する分子同定の試み:次世代の遺伝子治療への基礎的アプローチ
- Principal Investigator
  
  園田英一朗
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Molecular biology
- Research Institution
  Kyoto University

All 2007 2006 2005 2004 Other

All Journal Article

[Journal Article] Mechanism Underlying the Iron-Dependent Nuclear Export of the Iron-Responsive Transcription Factor Aft1p in Saccharomyces Cervisiae2007
- Author(s)
  Fujiwara N., Ueta R., Iwai K., Yamaguchi-Iwai Y.
- Journal Title
  
  Molecular Biology of the Cell (In revision)
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Zinc Transport Complexes Contribute to the Homeostatic Maintenance of Secretory Pathway Function in Vertebrate Cells2006
- Author(s)
  Ishihara K., Yamazaki T., Ishida Y., Suzuki T., Oda K., Nagao, M., Yamaguchi-Iwai Y., Kambe T.
- Journal Title
  
  The Journal of Biological Chemistry 281
  
  Pages: 17743-17750
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells2006
- Author(s)
  Wang, D., Masutani, H., Oka, S.I., Tanaka T., Yamaguchi-Iwai, Y., Nakamura, H., Yodoi, J.
- Journal Title
  
  The Journal of Biological Chemistry 281
  
  Pages: 7384-7391
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells.2006
- Author(s)
  Wang, D., Masutani, H., Oka, S.I., Tanaka, T., Yamaguchi-Iwai, Y., Nakamura, H., Yodoi, J.
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 7384-7391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Zinc Transport Complexes Contribute to the Homeostatic Maintenance of Secretory Pathway Function in Vertebrate Cells2006
- Author(s)
  Ishihara K., Yamazaki T., Ishida Y., Suzuki T., Oda K., Nagao M., Yamaguchi-Iwai Y., Kambe T.
- Journal Title
  
  The Journal of Biological Chemistry 281
  
  Pages: 17743-17750
- Data Source
  KAKENHI-PROJECT-18055016
[Journal Article] Sequence similarity and functional relationship among eukaryotic ZIP and CDF transporters2006
- Author(s)
  Kambe T., Suzuki T., Nagao M., Yamaguchi-Iwai Y.
- Journal Title
  
  Genomics, Proteomics ＆ Bioinformatics 4
  
  Pages: 1-9
- Data Source
  KAKENHI-PROJECT-18055016
[Journal Article] Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells2006
- Author(s)
  Ishihara, K, Yamazaki, T., Ishida, Y., Suzuki, T., Oda, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 17743-17750
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells2006
- Author(s)
  Wang, D., Masutani, H., Oka, S.I., Tanaka, T., Yamaguchi-Iwai, Y., Nakamura, H., Yodoi, J.
- Journal Title
  
  The Journal of Biological Chemistry 281
  
  Pages: 7384-7391
- Data Source
  KAKENHI-PROJECT-18055016
[Journal Article] Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells.2006
- Author(s)
  Wang, D., Masutani, H., Oka, S.I., Tanaka, T., Yamaguchi-Iwai, Y., Nakamura.H., Yodoi, J.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 7384-7391
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells.2006
- Author(s)
  Wang, D., Masutani, H., Oka, S.I., Tanaka, T., Yamaguchi-Iwai, Y., Nakamura, H., Yodoi, J.
- Journal Title
  
  J.Biol.Chem. 281(in press)
- Data Source
  KAKENHI-PROJECT-17054019
[Journal Article] Sequence similarity and functional relationship among eukaryotic ZIP and CDF transporters2006
- Author(s)
  Kambe T., Suzuki T., Nagao M., Yamaguchi-Iwai Y.
- Journal Title
  
  Genomics, Proteomics ＆ Bioinformatics 4
  
  Pages: 1-9
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells.2006
- Author(s)
  Ishihara, K, Yamazaki, T., Ishida, Y., Suzuki, T., Oda, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 17743-17750
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Sequence similarity and functional relationship among eukaryotic ZIP and CDF transporters.2006
- Author(s)
  Kambe, T., Suzuki, T., Nagao, M., Yamaguchi-Iwai, Y.
- Journal Title
  
  Genomics Proteomics Bioinformatics. 4
  
  Pages: 1-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells.2006
- Author(s)
  Wang, D., Masutani, H., Oka, S.I., Tanaka, T., Yamaguchi-Iwai, Y., Nakamura, H., Yodoi, J.
- Journal Title
  
  J.Biol.Chem. 281(in press)
- Data Source
  KAKENHI-PROJECT-16651097
[Journal Article] Sequence similarity and functional relationship among eukaryotic ZIP and CDF transporters.2006
- Author(s)
  Kambe, T., Suzuki, T., Nagao, M., Yamaguchi- Iwai, Y.
- Journal Title
  
  Genomics Proteomics Bioinformatics. 4
  
  Pages: 1-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Control of mitochondrial outer membrane permeabilization and Bcl-xL levels by thioredoxin 2 in DT40 cells.2006
- Author(s)
  Wang, D., Masutani, H., Oka, S.I., Tanaka, T., Yamaguchi-Iwai, Y., Nakamura, H., Yodoi, J.
- Journal Title
  
  J.Biol.Chem. 281(in press)
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] and assay of an oxidation-specific ubiquitin ligase, HOIL-1.2005
- Author(s)
  Iwai, K., Ishikawa, H., Kirisako, T., Identification, expression
- Journal Title
  
  Methods Enzymol. 398
  
  Pages: 256-271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.2005
- Author(s)
  Measday, V., Baetz, K., Guzzo, J., Yuen, K., Kwok, T., Sheikh, B., Ding, H., Ueta, R., Hoac, T., Cheng, B., Pot, I., Tong, A., Yamaguchi-Iwai, Y., Boone, C., Hieter, P., Andrews.B.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 102
  
  Pages: 13956-13961
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cells.2005
- Author(s)
  Suzuki, T., Ishihara, K., Migaki, H., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 30956-30962
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphates in vertebrate cells.2005
- Author(s)
  Suzuki, T, Ishihara, K., Migaki, H., Ishihara, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 30956-30962
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Identification, expression, and assay of an oxidation-specific ubiquitin ligase, HOIL-1.2005
- Author(s)
  Iwai, K., Ishikawa, H., Kirisako, T.
- Journal Title
  
  Methods Enzymol. 398
  
  Pages: 256-271
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Identification, expression, and assay of an oxidation-specific ubiquitin ligase, HOIL-1.2005
- Author(s)
  Iwai, K., Ishikawa, H., Kirisako, T.
- Journal Title
  
  Methods Enzymol. 398
  
  Pages: 256-271
- Data Source
  KAKENHI-PROJECT-17054019
[Journal Article] Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.2005
- Author(s)
  Suzuki, T, Ishihara, K., Migaki, H., Matsuura, W., Kohda, A., Okumura, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 637-643
- Data Source
  KAKENHI-PROJECT-12147204
[Journal Article] Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.2005
- Author(s)
  Suzuki, T, Ishihara, K., Migaki, H., Matsuura, W., Kohda, A., Okumura, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 637-643
- Data Source
  KAKENHI-PROJECT-16651097
[Journal Article] Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.2005
- Author(s)
  Measday, V., Baetz, K., Guzzo, J., Yuen, K., Kwok, T., Sheikh, B., Ding, H., Ueta, R., Hoac, T., Cheng, B., Pot, I., Tong, A., Yamaguchi-Iwai, Y., Boone, C., Hieter, P., Andrews, B.
- Journal Title
  
  Proc.Natl.Acad.Sci. 102
  
  Pages: 13956-13961
- Data Source
  KAKENHI-PROJECT-16651097
[Journal Article] Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2.2005
- Author(s)
  Ishikawa, H., Kato, M., Hori, H., Ishimori, K., Kirisako, T., Tokunaga, F., Iwai, K.
- Journal Title
  
  Mol Cell 19
  
  Pages: 171-181
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2.2005
- Author(s)
  Ishikawa, H., Kato, M., Hori, H., Ishimori, K., Kirisako, T., Tokunaga, F., Iwai, K.
- Journal Title
  
  Molecular Cell 19
  
  Pages: 171-181
- Data Source
  KAKENHI-PROJECT-17054019
[Journal Article] Identification, expression, and assay of an oxidation-specific ubiquitin ligase, HOIL-1.2005
- Author(s)
  Iwai, K., Ishikawa, H., Kirisako, T.
- Journal Title
  
  Methods Enzymol 398
  
  Pages: 256-271
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.2005
- Author(s)
  Measday, V., Baetz, K., Guzzo, J., Yuen, K., Kwok, T., Sheikh, B., Ding, H., Ueta, R., Hoac, T., Cheng, B., Pot, I., Tong, A., Yamaguchi-Iwai, Y., Boone, C., Hieter, P., Andrews, B.
- Journal Title
  
  Proc.Natl.Acad.Sci. 102
  
  Pages: 13956-13961
- Data Source
  KAKENHI-PROJECT-17054019
[Journal Article] Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatase in vertebrate cells.2005
- Author(s)
  Suzuki, T, Ishihara, K., Migaki, H., Ishihara, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 30956-30962
- Data Source
  KAKENHI-PROJECT-17054019
[Journal Article] Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.2005
- Author(s)
  Suzuki, T., Ishihara, K., Migaki, H., Matsuura, W., Kohda, A., Okumura, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 637-643
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.2005
- Author(s)
  Measday, V., Baetz, K., Guzzo, J., Yuen, K., Kwok, T., Sheikh, B., Ding, H., Ueta, R., Hoac, T., Cheng, B., Pot, I., Tong, A., Yamaguchi-Iwai, Y., Boone, C., Hieter, P., Andrews, B.
- Journal Title
  
  Proc.Natl.Acad.Sci. 102
  
  Pages: 13956-13961
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Zinc transporters, ZnT5, ZnT7 are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.2005
- Author(s)
  Suzuki, T., Ishihara, K., Migaki, H., Matsuura, W., Kohda, A., Okumura, K., Nagao, M., Yamaguchi- Iwai, Y., Kambe, T.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 637-643
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatase in vertebrate cells.2005
- Author(s)
  Suzuki, T, Ishihara, K., Migaki, H., Ishihara, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 30956-30962
- Data Source
  KAKENHI-PROJECT-16651097
[Journal Article] Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2.2005
- Author(s)
  Ishikawa, H., Kato, M., Hori, H., Ishimori, K., Kirisako, T., Tokunaga, F., Iwai, K.
- Journal Title
  
  Molecular Cell 19
  
  Pages: 171-181
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.2005
- Author(s)
  Suzuki, T, Ishihara, K., Migaki, H., Matsuura, W., Kohda, A., Okumura, K., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J.Biol.Chem 280
  
  Pages: 637-643
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.2005
- Author(s)
  Measday, V., Baetz, K., Guzzo, J., Yuen, K., Kwok, T., Sheikh, B., Ding, H., Ueta, R., Hoac, T., Cheng, B., Pot, I., Tong, A., Yamaguchi-Iwai, Y., Boone, C., Hieter, P., Andrews, B.
- Journal Title
  
  Proc.Natl.Acad.Sci. USA 102
  
  Pages: 13956-13961
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cells.2005
- Author(s)
  Suzuki, T., Ishihara, K., Migaki, H., Nagao, M., Yamaguchi-Iwai, Y., Kambe, T.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 30956-30962
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2.2005
- Author(s)
  Ishikawa, H., Kato, M., Hori, H., Ishimori, K., Kirisako, T., Tokunaga, F., Iwai, K.
- Journal Title
  
  Mol.Cell. 19
  
  Pages: 171-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains.2004
- Author(s)
  Tenno, T., Fujiwara, K., Tochio, H., Iwai, K., Morita, E.H., Hayashi, H., Murata, S., Hiroaki, H., Sato, M., Tanaka, K., Shirakawa, M.
- Journal Title
  
  Genes Cells. 9
  
  Pages: 865-875
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Overview of mammalian zinc transporter.2004
- Author(s)
  Kambe, T., Yamaguchi-Iwai, Y., Sasaki R., Nagao, M.
- Journal Title
  
  Cell.Mol.Life Sci. 61
  
  Pages: 49-68
- Data Source
  KAKENHI-PROJECT-12147204
[Journal Article] Overview of mammalian zinc transporter.2004
- Author(s)
  Kambe, T., Yamaguchi-Iwai, Y., Sasaki R., Nagao, M.
- Journal Title
  
  Cell.Mol.Life Sci. 61
  
  Pages: 49-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Structural basis of sugar-recognizing ubiquitin ligase.2004
- Author(s)
  Mizushima, T., Hirao, T., Yoshida, Y., Lee, S.J., Chiba, T., Iwai, K., Yamaguchi, Y., Kato, K., Tsukihara, T., Tanaka, K.
- Journal Title
  
  Nat.Struct.Mol.Biol. 11
  
  Pages: 365-370
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Overview of mammalian zinc transporter.2004
- Author(s)
  Kambe, T., Yamaguchi-Iwai, Y., Sasaki R., Nagao, M.
- Journal Title
  
  Cell. Mol. Life Sci. 61
  
  Pages: 49-68
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Overview of mammalian zinc transporter.2004
- Author(s)
  Kambe, T., Yamaguchi-Iwai, Y., Sasaki, R., Nagao, M.
- Journal Title
  
  Cell.Mol.Life Sci. 61
  
  Pages: 49-68
- Data Source
  KAKENHI-PROJECT-16651097
[Journal Article] 分子遺伝学アプローチによる鉄代謝機構研究の進展2004
- Author(s)
  岩井裕子
- Journal Title
  
  生化学 76
  
  Pages: 441-444
- NAID
  10013052821
- Data Source
  KAKENHI-PROJECT-12147204
[Journal Article] The Ubiquitin System : From Basic Mechanisms to the Patient Bed.2004
- Author(s)
  Ciechanover, A, Iwai, K.
- Journal Title
  
  IUBMB Life 56
  
  Pages: 193-201
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] 分子遺伝学アプローチによる鉄代謝機構研究の進展2004
- Author(s)
  岩井裕子
- Journal Title
  
  生化学 76
  
  Pages: 441-444
- NAID
  10013052821
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] 分子遺伝学アプローチによる鉄代謝機構研究の進展2004
- Author(s)
  岩井裕子
- Journal Title
  
  生化学 76
  
  Pages: 441-444
- NAID
  10013052821
- Data Source
  KAKENHI-PROJECT-16651097
[Journal Article] Mechanism Underlying the Iron-Dependent Nuclear Export of the Iron-Responsive Transcription Factor Aftlp in Saccharomyces Cervisiae
- Author(s)
  Ueta R., Fujiwara N., Iwai K., Yamaguchi-Iwai Y.
- Journal Title
  
  Molecular Biology of the Cell (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Mechanism Underlying the Iron-Dependent Nuclear Export of the Iron-Responsive Transcription Factor Aftlp in Saccharomyces Cervisiae
- Author(s)
  Fujiwara N., Ueta R., Iwai K., Yamaguchi-Iwai Y.
- Journal Title
  
  Molecular Biology of the Cell (In revision)
- Data Source
  KAKENHI-PROJECT-18055016
[Journal Article] Sequence similarlity and functional relationship among eukaryotic ZIP and CDF transporters
- Author(s)
  Kambe, K., Suzuki, T., Nagao, M., Yamaguchi-Iwai, Y.
- Journal Title
  
  Genomics Proteomics and Bioinformatics (in press)
- Data Source
  KAKENHI-PROJECT-17054019
[Journal Article] Mechanism Underlying the Iron-Dependent Nuclear Export of the Iron-Responsive Transcription Factor Aftlp in Saccharomyces Cervisiae
- Author(s)
  Ueta R., Fujiwara N., Iwai K., Yamaguchi-Iwai Y.
- Journal Title
  
  Molecular Biology of the Cell (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Sequence similarlity and functional relationship among eukaryotic ZIP and CDF transporters
- Author(s)
  Kambe, K., Suzuki, T., Nagao, M., Yamaguchi-Iwai, Y.
- Journal Title
  
  Genomics Proteomics and Bioinformatics (in press)
- Data Source
  KAKENHI-PROJECT-16370061
[Journal Article] Sequence similarity and functional relationship among eukaryotic ZIP and CDF transporters
- Author(s)
  Kambe, K., Suzuki, T., Nagao, M., Yamaguchi-Iwai, Y.
- Journal Title
  
  Genomics Proteomics and Bioinformatics (in press)
- Data Source
  KAKENHI-PROJECT-16651097

1. SONODA Eiichiro (50281093)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
2. TAKEDA Shunichi (60188191)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
3. TAKATA Minoru (30281728)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
4. IWAI Kazuhiro (60252459)

# of Collaborated Projects: 4 results

# of Collaborated Products: 45 results
5. YAGI Takashi (80182301)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 神戸大朋 (90303875)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. CIARAN Morri

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 江島洋介 (50127057)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐々木正夫 (20013857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐々木隆造 (60077378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HOEIJMAKAS J

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. THOMAS Lawre

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MORRISON Cia

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IWAI Yuko 岩井 裕子

Research Projects

Research Products

Co-Researchers

鉄イオンによる転写制御機構の分子基盤Principal Investigator

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鉄イオンによる転写制御の分子基盤Principal Investigator

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金属代謝機構のゲノムワイド解析Principal Investigator

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Roles of mitochondria in iron metabolismPrincipal Investigator

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Comprehensive study for mitochondrial iron metabolismPrincipal Investigator

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細胞内鉄濃度を制御する転写因子の鉄センシング機構と転写活性化機構Principal Investigator

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Myc癌遺伝子のターゲットとしての鉄代謝機構とその細胞増殖調節作用Principal Investigator

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細胞内鉄濃度を制御する転写因子の鉄センシング機構と転写活性化機構Principal Investigator

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DNA傷害の認識と修復・細胞周期停止へのシグナル伝達Principal Investigator

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Maintenance of telomere structure by MRE11 associated with the Nijmegen breakage syndrome protein.Principal Investigator

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Principal Investigator

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Project Period (FY)

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Principal Investigator

IWAI Yuko 岩井裕子