Sakurai Yu 櫻井遊

… Alternative Names

櫻井遊サクライユウ

SAKURAI Yu 櫻井遊

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Researcher Number	00707234
Other IDs
Affiliation (based on the past Project Information) *help	2023: 千葉大学, 大学院薬学研究院, 特任助教 2021 – 2023: 東北大学, 薬学研究科, 講師 2018 – 2020: 千葉大学, 大学院薬学研究院, 特任助教 2016: 北海道大学, 薬学研究科(研究院), 特任助教 2014: 北海道大学, 薬学研究科(研究院), その他 2013: 北海道大学, 薬学研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90120:Biomaterials-related / Basic Section 90110:Biomedical engineering-related / Medical pharmacy Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 55040:Respiratory surgery-related / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 脂質ナノ粒子 / siRNA / ｓｉＲＮＡ / がん / アクティブターゲティング / RNAパッケージング / 抗体デリバリー / ｍＲＮＡ / リガンド / mRNA … More / リンパ管内皮細胞 / 核酸医薬 / リンパ / 抗体 / リガンド修飾 / 核酸 / 転移 / 肺転移がん / 免疫チェックポイント阻害剤 / 肺転移 / ドラッグデリバリー / ドラッグデリバリーシステム / 腫瘍血管内皮細胞 / がん治療 / 血管新生阻害療法 / リポソーム … More Except Principal Investigator DDS / RNA創剤 / RNA創薬 / 標的化 / がん抗原 / RNA / ワクチン / 脂質ナノ粒子 / ネオ抗原 / 癌治療 / 凍結乾燥 / ＲＮＡワクチン / 癌免疫 / RNAワクチン / 肺癌 / siRNA送達 / ナノ粒子 / がん糖鎖抗原 / 光免疫療法 / 術中マーキング / 蛍光イメージング / rabbit orthotopic model / photosensityzer / マウスxenograftモデル / 5-ALA / アブスコパル効果 / レーザー / PDT / 内視鏡 / Photosesityzer / 光線力学的治療 / 肺がん / 胸腔鏡手術 / メタボリックシンドローム / オミックス創薬 / ナノテクノロジー / 血管 / 脂肪組織 / 肥満 / リポソーム / ドラッグデリバリーシステム Less

Establishment of antibody-loaded lipid nanoparticles based on RNA packaging technology and intracellular antibody deliveryPrincipal Investigator
- Principal Investigator
  
  櫻井遊
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tohoku University
Innovation of On-demand DDS platform of RNA therapeutics based on endothelial ATLAS
- Principal Investigator
  
  秋田英万
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tohoku University
Development of a Novel Lung Tumor Marking Method Utilizing Fluorescence Spectrum Analysis Thoracoscopy and 5-ALA
- Principal Investigator
  
  Aragaki Masato
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Hokkaido University
Development of photoimmunotherapy via O-glycans and siRNA delivery system using iRGD nanoparticles in lung cancer
- Principal Investigator
  
  加藤達哉
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Hokkaido University
Ready-tp-Use RNA-drug discovery for the acceleration of personalized cancer vaccine
- Principal Investigator
  
  秋田英万
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tohoku University
  Chiba University
Development of ligand modification onto the nanoparticle via click reaction and systematic evaluationPrincipal Investigator
- Principal Investigator
  
  Sakurai Yu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Tohoku University
  Chiba University
Development of new therapy for lung-metastasis cancer by selecitve siRNA delivery to vasculaturePrincipal Investigator
- Principal Investigator
  
  Sakurai Yu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Chiba University
Nanomix for a future treatment approach of metabolic syndrome
- Principal Investigator
  
  Kajimoto Kazuaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Institute of Advanced Industrial Science and Technology
  Hokkaido University
Development of siRNA delivery system tot tumor vesssels: optimization of intracellular trafficking and pharmacokineticsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Yu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Medical pharmacy
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013

All Journal Article Presentation Patent

[Journal Article] The Effect of Cholesterol Content on the Adjuvant Activity of Nucleic-Acid-Free Lipid Nanoparticles2024
- Author(s)
  Anindita Jessica、Tanaka Hiroki、Yamakawa Takuma、Sato Yuka、Matsumoto Chika、Ishizaki Kota、Oyama Taiji、Suzuki Satoko、Ueda Keisuke、Higashi Kenjirou、Moribe Kunikazu、Sasaki Kasumi、Ogura Yumika、Yonemochi Etsuo、Sakurai Yu、Hatakeyama Hiroto、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 16 Issue: 2 Pages: 181-181
- DOI
  10.3390/pharmaceutics16020181
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-21K18035
[Journal Article] An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses2023
- Author(s)
  Oyama Ryotaro、Ishigame Harumichi、Tanaka Hiroki、Tateshita Naho、Itazawa Moeko、Imai Ryosuke、Nishiumi Naomasa、Kishikawa Jun-ichi、Kato Takayuki、Anindita Jessica、Nishikawa Yoshifumi、Maeki Masatoshi、Tokeshi Manabu、Tange Kota、Nakai Yuta、Sakurai Yu、Okada Takaharu、Akita Hidetaka
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 19 Pages: 18758-18774
- DOI
  10.1021/acsnano.3c02251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-20KK0152, KAKENHI-PROJECT-21K18035
[Journal Article] Reactivation of Anticancer Immunity by Resetting Interorgan Crosstalk in Immune-Suppressive Cells with a Nanoparticulated Anti-Inflammatory Drug2023
- Author(s)
  Doi M, Tanaka H, Ohoto T, Miura N, Sakurai Y, Hatakeyama H, Akita H
- Journal Title
  
  Small
  
  Volume: - Issue: 16
- DOI
  10.1002/smll.202205131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-21K18035
[Journal Article] Ready-to-Use-Type Lyophilized Lipid Nanoparticle Formulation for the Postencapsulation of Messenger RNA2023
- Author(s)
  Tanaka Hiroki、Hagiwara Shinya、Shirane Daiki、Yamakawa Takuma、Sato Yuka、Matsumoto Chika、Ishizaki Kota、Hishinuma Miho、Chida Katsuyuki、Sasaki Kasumi、Yonemochi Etsuo、Ueda Keisuke、Higashi Kenjirou、Moribe Kunikazu、Tadokoro Takashi、Maenaka Katsumi、Taneichi Sakura、et al.
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 3 Pages: 2588-2601
- DOI
  10.1021/acsnano.2c10501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06545, KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-21K18035
[Journal Article] siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles2023
- Author(s)
  Sakurai Y, Yoshikawa K, Arai K, Kazaoka A, Aoki S, Ito K, Nakai Y, Tange K, Furihata T, Tanaka H, Akita H
- Journal Title
  
  J Control Release
  
  Volume: 353 Pages: 122-135
- DOI
  10.1016/j.jconrel.2022.11.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18320
[Journal Article] Development of a Ready-to-Use-Type RNA Vaccine Carrier Based on an Intracellular Environment-Responsive Lipid-like Material with Immune-Activating Vitamin E Scaffolds2023
- Author(s)
  Anindita Jessica、Tanaka Hiroki、Oyama Ryotaro、Hagiwara Shinya、Shirane Daiki、Taneichi Sakura、Nakai Yuta、Tange Kota、Hatakeyama Hiroto、Sakurai Yu、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 15 Issue: 12 Pages: 2702-2702
- DOI
  10.3390/pharmaceutics15122702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-21K18035
[Journal Article] Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine‐Loaded Lipid Nanoparticles2022
- Author(s)
  Masaki Gomi, Yu Sakurai, Minami Sato, Hiroki Tanaka, Yumi Miyatake, Koichi Fujiwara, Mizuki Watanabe, Satoshi Shuto, Yuta Nakai, Kota Tange, Hiroto Hatakeyama, Hidetaka Akita
- Journal Title
  
  Advanced Healthcare Materials
  
  Volume: 12 Issue: 9 Pages: 2202528-2202528
- DOI
  10.1002/adhm.202202528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-22KJ0465
[Journal Article] Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system2022
- Author(s)
  Maishi Nako、Sakurai Yu、Hatakeyama Hiroto、Umeyama Yui、Nakamura Takashi、Endo Rikito、Alam Mohammad Towfik、Li Cong、Annan Dorcas Akuba‐Muhyia、Kikuchi Hiroshi、Morimoto Hirofumi、Morimoto Masahiro、Akiyama Kosuke、Ohga Noritaka、Hida Yasuhiro、Harashima Hideyoshi、Hida Kyoko
- Journal Title
  
  Cancer Science
  
  Volume: online ahead of print Issue: 5 Pages: 1-1
- DOI
  10.1111/cas.15323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-21K10107, KAKENHI-PROJECT-20K10175, KAKENHI-PROJECT-21K10036, KAKENHI-PROJECT-19K18549
[Journal Article] Development of Sentinel LN Imaging with a Combination of HAase Based on a Comprehensive Analysis of the Intra-lymphatic Kinetics of LPs2021
- Author(s)
  Gomi Masaki、Sakurai Yu、Okada Takaharu、Miura Naoya、Tanaka Hiroki、Akita Hidetaka
- Journal Title
  
  Molecular Therapy
  
  Volume: 29 Issue: 1 Pages: 225-235
- DOI
  10.1016/j.ymthe.2020.09.014
- Data Source
  KAKENHI-PROJECT-20K20195
[Journal Article] Proteomics Analysis of Lymphatic Metastasis-Related Proteins Using Highly Metastatic Human Melanoma Cells Originated by Sequential <i>in Vivo</i> Implantation2021
- Author(s)
  Chida Katsuyuki、Sakurai Yu、Ohtani Asa、Masuda Takeshi、Ohtsuki Sumio、Tanaka Hiroki、Akita Hidetaka
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 10 Pages: 1551-1556
- DOI
  10.1248/bpb.b21-00463
- NAID
  130008095758
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-10-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05544, KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-21K18035
[Journal Article] Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material2021
- Author(s)
  Tanaka Hiroki、Takata Nae、Sakurai Yu、Yoshida Tokuyuki、Inoue Takao、Tamagawa Shinya、Nakai Yuta、Tange Kota、Yoshioka Hiroki、Maeki Masatoshi、Tokeshi Manabu、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 4 Pages: 544-544
- DOI
  10.3390/pharmaceutics13040544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06811, KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-20H00657, KAKENHI-PROJECT-20K12726, KAKENHI-PROJECT-21K06468
[Journal Article] Improvement of mRNA Delivery Efficiency to a T Cell Line by Modulating PEG-Lipid Content and Phospholipid Components of Lipid Nanoparticles2021
- Author(s)
  Tanaka Hiroki、Miyama Ryo、Sakurai Yu、Tamagawa Shinya、Nakai Yuta、Tange Kota、Yoshioka Hiroki、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 12 Pages: 2097-2097
- DOI
  10.3390/pharmaceutics13122097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-20H00657, KAKENHI-PROJECT-21K18035
[Journal Article] Optimization of Sentinel Lymph Node Imaging Methodology Using Anionic Liposome and Hyaluronidase2021
- Author(s)
  Sakurai Yu、Suzuoki Miho、Gomi Masaki、Tanaka Hiroki、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 9 Pages: 1462-1462
- DOI
  10.3390/pharmaceutics13091462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-21K18035, KAKENHI-PROJECT-22KJ0465
[Journal Article] Self‐Degradable Lipid‐Like Materials Based on “Hydrolysis accelerated by the intra‐Particle Enrichment of Reactant (HyPER)” for Messenger RNA Delivery2020
- Author(s)
  Tanaka Hiroki、...Sakurai Yu、Ueda Keisuke、Higashi Kenjirou、Moribe Kunikazu、Shinsho Eiji、Nishida Ruka、Fukuzawa Kaori、Yonemochi Etsuo、Okuwaki Koji、Mochizuki Yuji、Nakai Yuta、Tange Kota、Yoshioka Hiroki、Tamagawa Shinya、Akita Hidetaka
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 30 Issue: 34 Pages: 1910575-1910575
- DOI
  10.1002/adfm.201910575
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-20H00657
[Journal Article] Involvement of Caveolin-1-mediated transcytosis in the intratumoral accumulation of liposomes.2020
- Author(s)
  Sakurai Y, Kato A, Harashima H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 525 Issue: 2 Pages: 313-318
- DOI
  10.1016/j.bbrc.2020.02.086
- NAID
  120007032614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18351, KAKENHI-PROJECT-20K20195
[Journal Article] Mitochondrial Delivery of an Anticancer Drug Via Systemic Administration Using a Mitochondrial Delivery System That Inhibits the Growth of Drug-Resistant Cancer Engrafted on Mice2020
- Author(s)
  Yamada Yuma、Munechika Reina、Satrialdi、Kubota Fumika、Sato Yusuke、Sakurai Yu、Harashima Hideyoshi
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 109 Issue: 8 Pages: 2493-2500
- DOI
  10.1016/j.xphs.2020.04.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20195
[Journal Article] Improved Stability of siRNA-Loaded Lipid Nanoparticles Prepared with a PEG-Monoacyl Fatty Acid Facilitates Ligand-Mediated siRNA Delivery2020
- Author(s)
  Sakurai, Y., Mizumura, W., Ito, K., Iwasaki, K., Katoh, T., Goto, Y., Suga, H., Harashima, H.
- Journal Title
  
  Mol Pharm
  
  Volume: 17 Issue: 4 Pages: 1397-1404
- DOI
  10.1021/acs.molpharmaceut.0c00087
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04382, KAKENHI-PROJECT-18K18351, KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-19K22243, KAKENHI-PROJECT-17H04762
[Journal Article] Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors2020
- Author(s)
  Cho Riki、Sakurai Yu、Jones Haleigh Sakura、Akita Hidetaka、Hisaka Akihiro、Hatakeyama Hiroto
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 12 Pages: 3630-3630
- DOI
  10.3390/cancers12123630
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-19H03387, KAKENHI-PROJECT-20H00657
[Journal Article] Synergistic enhancement of cellular uptake with CD44-expressing malignant pleural mesothelioma by combining cationic liposome and hyaluronic acid-lipid conjugate2019
- Author(s)
  Sakurai Y., Kato A., Hida Y., Hamada J., Maishi N., Hida K., Harashima H
- Journal Title
  
  J Pharm Sci
  
  Volume: 108 Issue: 10 Pages: 3218-3224
- DOI
  10.1016/j.xphs.2019.06.012
- NAID
  120006941697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09715, KAKENHI-PUBLICLY-18H05092, KAKENHI-PROJECT-18K18351, KAKENHI-PROJECT-18H02996
[Journal Article] Effective Therapy Using a Liposomal siRNA that Targets the Tumor Vasculature in a Model Murine Breast Cancer with Lung Metastasis.2018
- Author(s)
  Sakurai Y, Hada T, Kato A, Hagino Y, Mizumura W, Harashima H.
- Journal Title
  
  Mol Ther Oncolytics.
  
  Volume: 11 Pages: 102-108
- DOI
  10.1016/j.omto.2018.10.004
- NAID
  120006551598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18351
[Journal Article] Innovative technologies in Nanomedicines: from passive targeting to active targeting/from controlled pharmacokinetics to controlled intracellular pharmacokinetics.2017
- Author(s)
  Sato Y, Sakurai Y, Kajimoto K, Nakamura T, Yamada Y, Akita H, Harashima H.
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 17 Issue: 1 Pages: 1-16
- DOI
  10.1002/mabi.201600179
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26282132, KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-26670741, KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-16K11180
[Journal Article] Liver-Specific Silencing of Lipin1 Reduces Fat Mass as Well as Hepatic Triglyceride Biosynthesis in Mice2016
- Author(s)
  Kajimoto K, Suemitsu E, Sato Y, Sakurai Y, Harashima H
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 10 Pages: 1653-1661
- DOI
  10.1248/bpb.b16-00353
- NAID
  130005598493
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26282132
[Journal Article] The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus2015
- Author(s)
  Sato S, Li K, Kameyama T, Hayashi T, Ishida Y, Murakami S, Watanabe T, Iijima S, Sakurai Y, Watashi K, Tsutsumi S, Sato Y, Akita H, Wakita T, Rice CM, Harashima H, Kohara M, Tanaka Y, Takaoka A
- Journal Title
  
  Immunity
  
  Volume: 42 Issue: 1 Pages: 123-132
- DOI
  10.1016/j.immuni.2014.12.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25253030, KAKENHI-PROJECT-25870015, KAKENHI-PROJECT-25893001, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-26893001
[Journal Article] Anti-angiogenic nanotherapy via active targeting system to tumor and adipose tissue vasculature.2015
- Author(s)
  Sakurai Y, Kajimoto K, Harashima H
- Journal Title
  
  Biomater Sci.
  
  Volume: 3 Issue: 9 Pages: 1253-1265
- DOI
  10.1039/c5bm00113g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26282132
[Journal Article] Advances in an active and passive targeting to tumor and adipose tissues.2015
- Author(s)
  Sakurai Y, Kajimoto K, Hatakeyama H, Harashima H
- Journal Title
  
  Exp Opin Drug Deliv
  
  Volume: 12 Issue: 1 Pages: 41-52
- DOI
  10.1517/17425247.2015.955847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26282132
[Journal Article] An aptamer ligand based liposomal nanocarrier system that targets tumor endothelial cells2014
- Author(s)
  Ara MN, Matsuda T, Hyodo M, Sakurai Y, Hatakeyama H, Ohga N, Hida K, Harashima H
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 25 Pages: 7110-7120
- DOI
  10.1016/j.biomaterials.2014.04.087
- NAID
  120005512022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893001, KAKENHI-PROJECT-26830101
[Journal Article] Improvement of doxorubicin effect using liposomal anti-polo like kinase 1 siRNA in human renal cell carcinomas2014
- Author(s)
  Sakurai Y, Hatakeyama H, Akita H, Harashima H.
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: in press Issue: 8 Pages: 2713-2719
- DOI
  10.1021/mp500245z
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24107502, KAKENHI-PROJECT-25893001
[Journal Article] Construction of an aptamer modified liposomal system targeted to tumor endothelial cells2014
- Author(s)
  Ara MN, Matsuda T, Hyodo M, Sakurai Y, Ohga N, Hida K, Harashima H
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 37 Pages: 1742-1749
- NAID
  130004703894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893001
[Journal Article] RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system2014
- Author(s)
  Yu Sakurai, Hiroto Hatakeyama, Yusuke Sato, Mamoru Hyodo, Hidetaka Akita, Noritaka Ohga, Kyoko Hida, Hideyoshi Harashima
- Journal Title
  
  J. Control. Release
  
  Volume: 173 Pages: 110-118
- DOI
  10.1016/j.jconrel.2013.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05557, KAKENHI-PROJECT-21229002, KAKENHI-PUBLICLY-24107502, KAKENHI-PROJECT-25462909, KAKENHI-PROJECT-25893001, KAKENHI-PROJECT-26830101
[Journal Article] Ligand density at the surface of a nanoparticle and different uptake mechanism: two important factors for successful siRNA delivery to liver endothelial cells2014
- Author(s)
  Akhter A, Hayashi Y, Sakurai Y, Ohga N, Hida K, Harashima H
- Journal Title
  
  Int J Pharm
  
  Volume: 475 Issue: 1-2 Pages: 227-237
- DOI
  10.1016/j.ijpharm.2014.08.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25893001
[Patent] 脾臓組織へ核酸を送達するための脂質ナノ粒子およびこれを用いて脾臓組織へ核酸を送達する方法2022
- Inventor(s)
  秋田英万、櫻井遊、田中浩揮ら
- Industrial Property Rights Holder
  秋田英万、櫻井遊、田中浩揮ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-051918
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20K20195
[Patent] 細胞指向性を有する脂質ナノ粒子2021
- Inventor(s)
  秋田英万，櫻井遊，田中浩揮ら
- Industrial Property Rights Holder
  秋田英万，櫻井遊，田中浩揮ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-161235
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K20195
[Patent] 核酸を脳組織に送達するために用いられる脂質ナノ粒子2021
- Inventor(s)
  秋田英万，田中浩揮，櫻井遊ら
- Industrial Property Rights Holder
  秋田英万，田中浩揮，櫻井遊ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-161237
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K20195
[Patent] 核酸をリンパ管内皮細胞に送達するために用いられる脂質ナノ粒子2021
- Inventor(s)
  秋田英万，櫻井遊，田中浩揮ら
- Industrial Property Rights Holder
  秋田英万，櫻井遊，田中浩揮ら
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-161239
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K20195
[Patent] センチネルリンパ節イメージング剤2020
- Inventor(s)
  秋田英万，櫻井遊，田中浩揮，五味昌樹
- Industrial Property Rights Holder
  国立大学法人千葉大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-044942
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K18351
[Patent] センチネルリンパ節イメージング剤2020
- Inventor(s)
  秋田英万、櫻井遊、五味昌樹、田中浩揮
- Industrial Property Rights Holder
  秋田英万、櫻井遊、五味昌樹、田中浩揮
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K20195
[Patent] 届出時名称：新規ヒアルロン酸誘導体を含む薬剤キャリア及び、新規ヒアルロン酸誘導体とカチオン性脂質による薬剤送達方法2018
- Inventor(s)
  加藤月、櫻井遊、原島秀吉、樋田京子、樋田泰浩、間石奈湖
- Industrial Property Rights Holder
  加藤月、櫻井遊、原島秀吉、樋田京子、樋田泰浩、間石奈湖
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K18351
[Presentation] Contribution of lipid composition and morphology of lipid nanoparticle to its immunostimulatory properties2024
- Author(s)
  essica Anindita, 田中浩揮、山川拓真、佐藤裕果、石崎弘汰、松本千佳、植田圭祐、東顕二郎、森部久仁一、佐々木香純、米持悦生、櫻井遊、秋田英万
- Organizer
  日本薬剤学会　第38年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] Lipid composition and morphology of lipid nanoparticle contributed to its immuostimulatory properties2024
- Author(s)
  Jessica Anindita, 田中浩揮、植田圭祐、東顕二郎、森部久仁一、佐々木香純、米持悦生、櫻井遊、秋田英万
- Organizer
  日本DDS学会　第39年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 2本鎖アンチセンスオリゴ核酸内封 Ready-to-Use型脂質ナノ粒子の開発2024
- Author(s)
  松本千佳、田中浩揮、佐藤裕果、中井悠太、丹下耕太、櫻井遊、秋田英万
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 脂質ナノ粒子を用いた血液脳関門を構成する脳毛細血管内皮細胞への核酸送達システムの開発2024
- Author(s)
  渡邉妃香、櫻井遊、西尾一真、橋本耕平、原田純希、大山遼太朗、中井裕太、丹下耕太、田中浩揮、秋田英万
- Organizer
  日本DDS学会　第39年会
- Data Source
  KAKENHI-PROJECT-23H00542
[Presentation] リンパ球指向性を有する脂質ナノ粒子の開発2022
- Author(s)
  岩崎光希、櫻井遊、丹下耕太、中井悠太、田中浩揮、秋田英万
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] アニオン性脂質ナノ粒子による脾臓標的化mRNA送達技術の開発2022
- Author(s)
  堀瑞歩、櫻井遊、五味昌樹、中井悠太、丹下耕太、田中浩揮、秋田英万
- Organizer
  第7回日本核酸医薬学会年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] Ready-to-Use型LNP製剤の開発2022
- Author(s)
  田中浩揮、萩原伸哉、山川拓真、白根大貴、高田奈依、櫻井遊、福田翔、福澤薫、米持悦生、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  第7回日本核酸医薬学会年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] Ready-to-Use型mRNA内封脂質ナノ粒子製剤の物性評価2022
- Author(s)
  山川拓真、田中浩揮、萩原伸哉、櫻井遊、佐々木香純、米持悦生、福澤薫、中井悠太、丹下耕太、秋田英万
- Organizer
  遺伝子・デリバリー研究会　第21回シンポジウム・第20回夏季セミナー
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 一工程で使用可能なmRNA内封脂質ナノ粒子Ready-to-Use液体製剤の開発2022
- Author(s)
  佐藤裕果、田中浩揮、萩原伸哉、山川拓真、櫻井遊、中井悠太、丹下耕太、秋田英万
- Organizer
  第43回生体膜と薬物相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] mRNA delivery to Secondary Lymphoid Tissues by Lipid Nanoparticles Loading Phosphatidylserine2022
- Author(s)
  Gomi M, Sakurai Y, Tanaka H, Sato M, Miyatake Y, Fujiwara K, Watanabe M, Shuto S, Nakai Y, Tange K, Akita H
- Organizer
  NIMS WEEK2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 機能素子を用いたsiRNA搭載脂質ナノ粒子による新規がん治療法の開発2022
- Author(s)
  櫻井遊
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] Ready-to-Use型脂質ナノ粒子製剤の物性評価2021
- Author(s)
  "山川拓真、田中浩揮、萩原伸哉、白根大貴、高田奈依、櫻井遊、福田翔、福澤薫、米持悦生、玉川晋也、中井悠太、丹下耕太、秋田英万 "
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 抗腫瘍免疫の正常化を介したRISET療法の作用機序解析と応用展開2021
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 使用者の利便性を限りなく追求したmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] リポソームを用いたセンチネルリンパ節イメージング技術の開発2021
- Author(s)
  鈴置真歩、櫻井遊、五味昌樹、田中浩輝、秋田英万
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 水和の一工程のみで使用可能なmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  若手シンポジウム（日本核酸医薬学会第６回年会）
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] リンパ管内皮細胞選択的siRNA送達システムの開発2021
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] T細胞エンジニアリングを可能とする脂質ナノキャリアの開発2021
- Author(s)
  三山亮、田中浩揮、中井悠太、櫻井遊、玉川晋也、丹下耕太、秋田英万
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] ビタミンE足場型pH応答性材料が誘導するワクチン効果メカニズムの解明2021
- Author(s)
  大山遼太朗，舘下菜穂，Jessica Anindita，田中浩揮，三浦尚也，櫻井遊，石亀晴道，岡田隆陽，丹下耕太，中井裕太，吉岡宏樹，秋田英万
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] ビタミンE足場型新規材料を用いたmRNAがんワクチン技術の開発とその機能解析（学生シンポジウム）2021
- Author(s)
  大山遼太朗、舘下菜穂、Jessica Anindita、田中浩揮、三浦尚也、櫻井遊、石亀晴道、岡田峰陽、丹下耕太、中井裕太、吉岡宏樹、秋田英万
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] エクソソームのリンパシステム内動態解析とそのメカニズムの解明2021
- Author(s)
  大谷あさ、櫻井遊、千田克幸、田中浩輝、秋田英万
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 一工程でmRNAを内封できるReady-to-Use型脂質ナノ粒子製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] リンパ球指向性を有する脂質ナノ粒子の創製2021
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] メラノーマから放出されるエクソソームの生体内動態の解明2021
- Author(s)
  大谷あさ、櫻井遊、千田克幸、田中浩輝、秋田英万
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 使用者の利便性を限りなく追求したmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 水和の一工程のみで使用可能なmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  日本核酸医薬学会第６回年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 使用者の利便性を限りなく追求したmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] センチネルリンパ節検出を志向したリンパ節標的型リポソームの開発2021
- Author(s)
  五味昌樹、櫻井遊、三浦尚也、田中浩揮、秋田英万
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 使用者の利便性を限りなく追求したmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] pH応答性脂質を基盤としたT細胞へのmRNA送達技術の開発2021
- Author(s)
  三山亮、田中浩揮、中井悠太、櫻井遊、玉川晋也、丹下耕太、秋田英万
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] ビタミンE足場型材料が誘導する免疫活性化メカニズムの解明2021
- Author(s)
  "大山遼太朗, Jessica Anindita，田中浩揮, 櫻井遊，石亀晴道，岡田峰陽，丹下耕太，中井裕太，吉岡宏樹，秋田英万 "
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 水和の一工程のみで使用可能なmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  日本核酸医薬学会第６回年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 組織間の免疫抑制クロストークを標的としたがん免疫療法の提唱2021
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 組織間のクロストークを標的とした新規がん治療戦略の提唱2021
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] mRNA内封脂質ナノ粒子Ready-to-Use製剤の物性評価2021
- Author(s)
  "山川拓真、田中浩揮、萩原伸哉、白根大貴、高田奈依、櫻井遊、福田翔、福澤薫、米持悦生、玉川晋也、中井悠太、丹下耕太、秋田英万 "
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] ビタミンE足場型材料を基盤とするmRNAワクチンの開発2021
- Author(s)
  大山遼太朗，舘下菜穂，Jessica Anindita，田中浩揮，三浦尚也，櫻井遊，石亀晴道，岡田隆陽，丹下耕太，中井裕太，吉岡宏樹，秋田英万
- Organizer
  日本核酸医薬学会第６回年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] mRNAとビタミンE足場型の新規pH応答性材料を基盤とするがんワクチン技術の開発2020
- Author(s)
  大山遼太朗、舘下菜穂、Jessica Anindita、田中浩揮、三浦尚也、櫻井遊、石亀晴道、岡田峰陽、秋田英万
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] リンパ管内皮細胞の共移植がメラノーマの腫瘍微小環境に与える影響の解析2020
- Author(s)
  新井健太、櫻井遊、千田克幸、梅原健太、降幡知巳、秋田英万
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] リポソームのリンパシステム内動態の網羅的解析とセンチネルリンパ節イメージングへの応用2020
- Author(s)
  櫻井遊、五味昌樹、三浦尚也、田中浩揮、秋田英万
- Organizer
  第44回リンパ学会総会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] リポソームの物性制御によるリンパ節標的技術の開発2020
- Author(s)
  五味昌樹、櫻井遊、田中浩揮、秋田英万
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 抗腫瘍免疫の正常化を目的とした脾臓の炎症環境の改善：RISET療法の提唱2020
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 原発巣リンパ管内皮細胞がメラノーマのリンパ節転移に与える影響の解析2020
- Author(s)
  新井健太、櫻井遊、千田克幸、梅原健太、降幡知己、秋田英万
- Organizer
  第44回リンパ学会総会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] ビタミンE足場型pH応答性新規材料を基盤とするmRNAがんワクチンの開発2020
- Author(s)
  大山遼太朗、舘下菜穂、Jessica Anindita、田中浩揮、三浦尚也、櫻井遊、石亀晴道、岡田峰陽、丹下耕太、中井裕太、吉岡宏樹、秋田英万
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 人工mRNAベクターを基盤とするT細胞エンジニアリング技術の開発2020
- Author(s)
  三山亮、田中浩揮、中井悠太、櫻井遊、玉川晋也、丹下耕太、秋田英万
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] リンパ管内皮細胞を標的とする核酸搭載脂質ナノ粒子の開発2020
- Author(s)
  櫻井遊、阿部のどか、小笠原諭、加藤幸成、村田武士、丹下耕太、中井悠太、吉岡宏樹、玉川晋也、田中浩揮、秋田英万
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] リンパ節高転移性メラノーマ細胞株の樹立とタンパク質発現の解析2020
- Author(s)
  千田克幸、櫻井遊、新井健太、梅原健太、増田豪、大槻純男、降幡知巳、田中浩輝、秋田英万
- Organizer
  第44回リンパ学会総会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] エマルション型ナノ粒子製剤における薬物の疎水性が血中動態に及ぼす影響2020
- Author(s)
  土井瑞貴、田中浩揮、櫻井遊、秋田英万
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 脾臓に対する抗炎症薬送達(RISET療法)の動態およびメカニズム解析2020
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 人工mRNAベクターを基盤とするT細胞エンジニアリング技術の開発2020
- Author(s)
  三山亮、田中浩揮、中井悠太、櫻井遊、玉川晋也、丹下耕太、秋田英万
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] 抗炎症薬搭載ナノ粒子による脾臓を標的とした新規がん治療戦略の開発2020
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K20195
[Presentation] サイズ・表面電化に基づく脂質ナノ粒子のリンパシステム内動態制御2019
- Author(s)
  五味昌樹、櫻井遊、田中浩揮、三浦尚哉、秋田新介、山路佳久、三科信之、秋田英万．
- Organizer
  第25回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-18K18351
[Presentation] リンパ管内皮細胞標的化siRNA搭載脂質ナノ粒子の開発2019
- Author(s)
  阿部のどか、櫻井遊、小笠原諭、村田武士、丹下耕太、中井悠太、吉岡宏樹、玉川晋也、田中浩揮、秋田英万．
- Organizer
  第25回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-18K18351
[Presentation] ビタミンE足場型pH応答性脂質用材料を基盤とするmRNAワクチンの開発2019
- Author(s)
  大山遼太郎、館下菜穂、Jessica Anindita、田中浩揮、三浦尚也、櫻井遊、丹下耕太、中井悠太、吉岡宏樹、秋田英万．
- Organizer
  第25回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-18K18351
[Presentation] 転移がんの血管を標的とするsiRNA封入脂質ナノ粒子を用いた治療法の開発2019
- Author(s)
  櫻井遊、羽田智也、加藤月、萩野裕太、水村航、原島秀吉．
- Organizer
  第25回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-18K18351
[Presentation] Development of siRNA delivery system by EpCAM-targeting lipid nanoparticles using non-standard macrocyclic peptide.2018
- Author(s)
  Yu Sakurai, Wataru Mizumura, Hideyoshi Harashima
- Organizer
  the 29th Annual Meeting of the European Society for Biomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18351
[Presentation] 腫瘍血管内皮細胞へのin vivo siRNA導入法の確立2013
- Author(s)
  2) 櫻井遊、畠山浩人、佐藤悠介、兵藤守、秋田英万、大賀則孝、樋田京子、原島秀吉
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル、大阪
- Data Source
  KAKENHI-PROJECT-25893001
[Presentation] 腫瘍血管内皮細胞へのアクティブターゲティング型siRNAデリバリーシステム2013
- Author(s)
  櫻井遊、畠山浩人、秋田秀万、大賀則孝、樋田京子、原島秀吉
- Organizer
  第23回アンチセンスシンポジウム
- Place of Presentation
  徳島大学大塚講堂、徳島
- Data Source
  KAKENHI-PROJECT-25893001
[Presentation] Development of an in vivo Active siRNA Delivery System to Tumor Endothelial Cells using Cyclic RGD-modified Liposomal siRNA2013
- Author(s)
  1) Y. Sakurai, H. Hatakeyama, Y. Sato, M. Hyodo, H. Akita, H. Harashima
- Organizer
  9 th Annual Meeting of Oligonucleotide Therapeutics Society
- Place of Presentation
  Royal Continental Hotel、ナポリ、イタリア
- Data Source
  KAKENHI-PROJECT-25893001

1. 加藤達哉 (20624232)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 樋田泰浩 (30399919)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 秋田英万 (80344472)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
4. Kajimoto Kazuaki (10416216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Aragaki Masato (30788245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 海老原裕磨 (50632981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 加賀基知三 (80224335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 畑中佳奈子 (10399834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小川美香子 (20344351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 畑中豊 (30589924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中浩揮 (60801743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
12. 松下博和 (80597782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 内田康雄 (70583590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIDA Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. MAISHI Nako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. HIGASHI Kenjirou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. GOTO Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 小原道法

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 山田勇磨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 井上貴雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 畠山浩人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 森部久仁一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 植田圭祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 渡邉瑞貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakurai Yu 櫻井 遊

櫻井 遊 サクライ ユウ

SAKURAI Yu 櫻井 遊

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Establishment of antibody-loaded lipid nanoparticles based on RNA packaging technology and intracellular antibody deliveryPrincipal Investigator

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Innovation of On-demand DDS platform of RNA therapeutics based on endothelial ATLAS

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Development of a Novel Lung Tumor Marking Method Utilizing Fluorescence Spectrum Analysis Thoracoscopy and 5-ALA

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Development of photoimmunotherapy via O-glycans and siRNA delivery system using iRGD nanoparticles in lung cancer

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Ready-tp-Use RNA-drug discovery for the acceleration of personalized cancer vaccine

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Development of ligand modification onto the nanoparticle via click reaction and systematic evaluationPrincipal Investigator

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Development of new therapy for lung-metastasis cancer by selecitve siRNA delivery to vasculaturePrincipal Investigator

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Nanomix for a future treatment approach of metabolic syndrome

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Development of siRNA delivery system tot tumor vesssels: optimization of intracellular trafficking and pharmacokineticsPrincipal Investigator

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[Journal Article] The Effect of Cholesterol Content on the Adjuvant Activity of Nucleic-Acid-Free Lipid Nanoparticles2024

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[Journal Article] An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses2023

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[Journal Article] Reactivation of Anticancer Immunity by Resetting Interorgan Crosstalk in Immune-Suppressive Cells with a Nanoparticulated Anti-Inflammatory Drug2023

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[Journal Article] Ready-to-Use-Type Lyophilized Lipid Nanoparticle Formulation for the Postencapsulation of Messenger RNA2023

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Sakurai Yu 櫻井遊

櫻井遊サクライユウ

SAKURAI Yu 櫻井遊