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Akita Hidetaka  秋田 英万

ORCIDConnect your ORCID iD *help
… Alternative Names

AKITA Hidetaka  秋田 英万

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Researcher Number 80344472
Other IDs
External Links
Affiliation (Current) 2021: 千葉大学, 大学院薬学研究院, 教授
Affiliation (based on the past Project Information) *help 2016 – 2020: 千葉大学, 大学院薬学研究院, 教授
2015: 北海道大学, 薬学研究科(研究院), 准教授
2012: 北海道大学, 大学院・薬学研究院, 准教授
2011: 北海道大学, 大学院薬学研究院, 准教授
2011: Hokkaido University, 薬学研究科(研究院), 助教 … More
2009 – 2010: 北海道大学, 大学院・薬学研究院, 准教授
2007 – 2009: Hokkaido University, Fac Pharm. Sci, Associate Professor
2006: 北海道大学, 大学院 薬学研究院, 助手
2006: 北海道大学, 大学院薬学研究院, 助手
2003 – 2005: 北海道大学, 大学院・薬学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Medical pharmacy / Science and Engineering / Biomedical engineering/Biological material science / Physical pharmacy / Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering / Pharmaceutical Sciences and related fields
Except Principal Investigator
Biomedical engineering/Biological material science / Medical pharmacy / Biological Sciences … More / Drug development chemistry / Physical pharmacy / Respiratory organ internal medicine / Biomedical engineering/Biomaterial science and engineering / Plastic surgery / Pharmaceutical Sciences and related fields Less
Keywords
Principal Investigator
細胞内動態 / 遺伝子デリバリー / 細胞内動態制御 / 遺伝子治療 / 人工ベクター / アデノウイルス / リアルタイムイメージング / トランスサイトーシス / ナノ粒子 / ナノ材料 … More / ナノバイオ / ナノマシン / エンドサイトーシス脱出 / 核膜誘過 / 核膜透過 / 定量化 / mRNA検出 / heterogeneity / 極性細胞 / リポソーム / 肺 / 遺伝子・核酸デリバリー / 自己組織化 / 癌免疫 / 環境応答性材料 / ワクチン / DNA / 遺伝子 / 薬学 / DNA / 癌免役 / ドラッグデリバリーシステム / リガンド / 脂質様材料 / DDS / 脂質 / 癌治療 / DDS / 体内動態 / プロドラッグ / 炎症 … More
Except Principal Investigator
MEND / 遺伝子治療 / siRNA / ミトコンドリア / オクタアルギニン / がん / 遺伝子デリバリー / 多機能性エンベロープ型ナノ構造体 / ハイドロダイナミクス法 / ワクチン / 抗腫瘍効果 / アジュバント / 非ウィルスベクター / 外来DNA / 核内動態 / 核内動態制御 / 細胞内動態制御 / KALA / 人工遺伝子デリバリーシステム / 非ウイルスベクター / 核酸医薬 / MTS / オルガネラターゲティング / 多重型 / 細胞内ターゲティング / 遺伝子導入 / MMP / がん治療 / PPD-MEND / エンドサイトーシス / トランスサイトーシス / 血管透過 / 2型糖尿病 / 網羅的解析 / 遺伝子診断 / 遺伝子デリバリーシステム / GALA / IRO / カベオラ / R8-NEND / デリバリーシステム / PPD / エンドソーム脱出 / トポロジー / ナノ構造体 / 細胞性免疫 / 細胞透過性ペプチド / MHCクラス-I / 抗原提示 / ナノマシン / マイクロ流路 / ナノパッケージング / pH-感受性カチオニック脂質 / 還元環境応答性 / ミトコンドリア送達 / 自己活性化システム / バイセル / パッケージング / 核送達 / 機能性核酸 / スイッチ機能 / DNAワクチン / 樹状細胞 / ウイルスベクター / スイッチ / スイツチ / 細胞内シグナル / ソーティング素子 / 細胞内動態 / アデノウイルス / 定量的評価 / gene delivery system / endocytosis / octaarginin / programmed packaging / 発現効率 / nonviral vector / exogenous DNA / gene therapy / intranuclear disposition / transgene expression / 多機能性エンベロープナノ構造体 / Nrf2 / 薬物送達システム / リンパ浮腫 / リンパ管 / 超音波 / カニュレーション / リンパ管静脈吻合 / リンパ外科 / DDS / リンパ節 / リンパ菅 / リンパ管細静脈吻合 / 定量評価 / drug delivery system / ナノ粒子 / がん分子標的 / ドラッグデリバリー / がん分子標的治療 / がん型OATP1B3 / がんドラッグデリバリーシステム / 転写リプログラミング Less
  • Research Projects

    (26 results)
  • Research Products

    (196 results)
  • Co-Researchers

    (33 People)
  •  自己ナノ組織化プロドラッグの創製:癌免疫サイクルの矯正と癌治療への応用展開Principal InvestigatorOngoing

    • Principal Investigator
      秋田 英万
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Chiba University
  •  抗癌剤を利用しない癌治療用ナノDDS :RISET療法の提唱と機能検証Principal InvestigatorOngoing

    • Principal Investigator
      秋田 英万
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Chiba University
  •  Development of the nanoDDS platform for the penetrarion or intracellular delivery: Develioment of the rapid ligand-identification system and in vivo control of intracellular traffickingPrincipal Investigator

    • Principal Investigator
      Akita Hidetaka
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Pharmaceutical Sciences and related fields
    • Research Institution
      Chiba University
  •  Percutaneous Access to the Lymphatic System Using Ultrasonography and Translymphatic DDS Using Nanoparticles

    • Principal Investigator
      Akita Shinsuke
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Chiba University
  •  Development of cancer suicide gene therapy using RNA trans-splicing technology

    • Principal Investigator
      Furihata Tomomi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Pharmaceutical Sciences and related fields
    • Research Institution
      Chiba University
  •  Debelopment of nano satelite-organized archetecture as a technology to control an intracellular traffickingPrincipal Investigator

    • Principal Investigator
      Akita Hidetaka
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Physical pharmacy
    • Research Institution
      Chiba University
      Hokkaido University
  •  Innovation of multi-Drug delivery platform based on the ssPalm: Immune-engineering and cancer therapyPrincipal Investigator

    • Principal Investigator
      Hidetaka Akita
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Chiba University
      Hokkaido University
  •  Challenge for treatment of refractory lung diseases using a multifunctional envelope-type nanodevice that targets the lung endothelium

    • Principal Investigator
      Nishimura Masaharu
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hokkaido University
  •  Development of nanomachine for mitochondrial gene therapy targeted to cells derived from mitochondrial disease patients

    • Principal Investigator
      YAMADA Yuma
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Hokkaido University
  •  MENDで拓く遺伝子治療への道:遺伝子の運び屋からナノマシンへ

    • Principal Investigator
      原島 秀吉
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hokkaido University
  •  Novel gene delivery system with switch function

    • Principal Investigator
      HARASHIMA Hideyoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Physical pharmacy
    • Research Institution
      Hokkaido University
  •  肺血管標的及び透過型DDSを目的としたナノ粒子のインビボ細胞内動態制御法の確立Principal Investigator

    • Principal Investigator
      秋田 英万
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      Hokkaido University
  •  Control of intranuclear disposition of DNA for gene therapy

    • Principal Investigator
      KAMIYA Hiroyuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Ehime University
  •  Multifunctional Envelope-type Nano Device as non-viral gene delivery system for cancer therapy

    • Principal Investigator
      HARASHIMA Hideyoshi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  細胞内動態の精密制御に基づいたナノキャリアのトランスサイトーシス輸送制御の新戦略Principal Investigator

    • Principal Investigator
      秋田 英万
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Hokkaido University
  •  抗原提示バランスとアジュバントの制御に基づいたオーダーメイド癌ワクチン

    • Principal Investigator
      原島 秀吉
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Hokkaido University
  •  DNA・mRNAの細胞内高感度可視化情報に基づく高性能人工遺伝子べクターの創製Principal Investigator

    • Principal Investigator
      秋田 英万
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hokkaido University
  •  Development of new-generation gene vectors by a control of intracellular trafficking and dispersion based in a real-time imaging of DNAPrincipal Investigator

    • Principal Investigator
      AKITA Hidetaka
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Hokkaido University
  •  がん選択的多機能性エンベロープ型ナノ構造体の開発とがん遺伝子治療への応用

    • Principal Investigator
      原島 秀吉
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  1分子イメージングに基づく細胞内動態・解離制御型デリバリーシステムの創製Principal Investigator

    • Principal Investigator
      秋田 英万
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hokkaido University
  •  Development of in vivo gene delivery system for siRNA and genome wide screening of type-two diabetes related genes in mice and rats

    • Principal Investigator
      HARASHIMA Hideyoshi
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Hokkaido University
  •  Novel DNAs for efficient and durable transgene expression

    • Principal Investigator
      KAMIYA Hiroyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hokkaido University
  •  ミトコンドリアを標的とする多重型・多機能性エンベロープ型ナノ構造体の開発

    • Principal Investigator
      HARASHIMA Hideyoshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Hokkaido University
  •  ウイルスの細胞内動態定量化情報に基づいた人工遺伝子ベクター開発の新規アプローチPrincipal Investigator

    • Principal Investigator
      秋田 英万
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Hokkaido University
  •  核膜透過過程の新規定量化システムの構築と核膜輸送の基質認識性、機能多様性の解析Principal Investigator

    • Principal Investigator
      秋田 英万
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Hokkaido University
  •  Development of Multifunctional Envelope type Nano Device based on Programmed Packaging

    • Principal Investigator
      HARASHIMA Hideyoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      HOKKAIDO UNIVERSITY

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] ドラッグキャリア設計入門~DDSからナノマシンまで~2018

    • Author(s)
      秋田 英万
    • Total Pages
      21
    • Publisher
      丸善出版
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Book] Nonviral Vectors for Gene Therapy (Vol. 88): Lipid- and Polymer-based Gene Transfer2014

    • Author(s)
      Yusuke Sato, Takashi Nakamura, Yuma Yamada, Hidetaka Akita, Hideyoshi Harashima
    • Total Pages
      428
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-26282131
  • [Book] Delivery of Nucleic Acids and Gene Delivery2011

    • Author(s)
      H.Akita, H.Hatakeyama, I.A.Khalil, Y.Yamada, H.Harashima
    • Total Pages
      34
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Book] バイオテクノロジーシリーズ蛍光イメージング/MRIプローブの開発2011

    • Author(s)
      秋田英万、山田勇磨,中村孝司、畠山浩人、林泰弘、梶本和昭、原島秀吉
    • Total Pages
      10
    • Publisher
      CMC出版
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Book] A Novel Nonviral Gene Delivery System : Multifunctional Envelope-type Nano Device2010

    • Author(s)
      H.Hatakeyama, H.Akita, et al
    • Total Pages
      33
    • Publisher
      T.Scheper, Volume Editors I.Endo and T.Nagamune, Springer
    • Data Source
      KAKENHI-PROJECT-22659006
  • [Book] Adv Biochem Eng Biotechnol(A Novel Nonviral Gene Delivery System: Multifunctional Envelope-Type Nano Device.)2009

    • Author(s)
      H.Hatakeyama, H.Akita, K.Kogure, H.Harashima
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Book] 分子薬物動態学(第17章高分子・遺伝子の体内動態の制御(細胞内動態を中心に))2008

    • Author(s)
      秋田英万、原島秀吉
    • Total Pages
      19
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Book] Contrib Nephrol (Nonviral gene delivery)2008

    • Author(s)
      Akita H, Harashima H.
    • Total Pages
      19
    • Publisher
      KARGER
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Book] "New Drug Delivery System and Application to Gene Therapy" Knaeblein, Muller Eds. Modern Biopharmaceuticals.2005

    • Author(s)
      K.Kogure, H.Akita, H.Kamiya, H.Harashima.
    • Total Pages
      15
    • Publisher
      Wiley-VCH
    • Data Source
      KAKENHI-PROJECT-17659039
  • [Book] 1Pharmacokinetics of Gene Delivery in Cells. In Non-viral Gene Therapy: Gene Design and Delivery Edit. by Kazunari Taira, Kazunori Kataoka,2005

    • Author(s)
      H.Akita, I.A Khalil, K.Kogure, H.Harashima.
    • Total Pages
      19
    • Publisher
      Springer-Verlag Tokyo, Inc.
    • Data Source
      KAKENHI-PROJECT-17659039
  • [Journal Article] Intraoperative Detection of Efferent Lymphatic Vessels Emerging from Lymph Node during Lymphatic Microsurgery.2019

    • Author(s)
      Yamaji Yoshihisa、Kuriyama Motone、Tokumoto Hideki、Ishigaki Tatsuya、Tezuka Takafumi、Ogata Hideyuki、Kubota Yoshitaka、Mitsukawa Nobuyuki、Akita Shinsuke
    • Journal Title

      J Reconstr Microsurg.

      Volume: Epub ahead of print Pages: 372-378

    • DOI

      10.1055/s-0038-1677039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11529
  • [Journal Article] A hepatic pDNA delivery system based on an intracellular environment sensitive vitamin E-scaffold lipid-like material with the aid of an anti-inflammatory drug.2019

    • Author(s)
      Togashi R, Tanaka H, Nakamura S, Yokota H, Tange K, Nakai Y, Yoshioka H, Harashima H, Akita H
    • Journal Title

      J Control Release.

      Volume: 279 Pages: 262-270

    • DOI

      10.1016/j.jconrel.2018.04.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-17K19473
  • [Journal Article] Development of a mouse model for the visual and quantitative assessment of lymphatic trafficking and function by in vivo imaging2018

    • Author(s)
      Yamaji Yoshihisa、Akita Shinsuke、Akita Hidetaka、Miura Naoya、Gomi Masaki、Manabe Ichiro、Kubota Yoshitaka、Mitsukawa Nobuyuki
    • Journal Title

      Scientific Reports

      Volume: 8

    • DOI

      10.1038/s41598-018-23693-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11529, KAKENHI-PROJECT-16K20351
  • [Journal Article] The delivery of mRNA to colon inflammatory lesions by lipid-nano-particles containing environmentally-sensitive lipid-like materials with oleic acid scaffolds2018

    • Author(s)
      Tanaka H, Watanabe A, Konishi M, Nakai Y, Yoshioka H, Ohkawara T, Takeda H, Harashima H, Akita H.
    • Journal Title

      Heliyon

      Volume: 4

    • DOI

      10.1016/j.heliyon.2018.e00959

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K05500, KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-17K19473
  • [Journal Article] In Vivo Introduction of mRNA Encapsulated in Lipid Nanoparticles to Brain Neuronal Cells and Astrocytes via Intracerebroventricular Administration.2018

    • Author(s)
      Tanaka H, Nakatani T, Frihata T, Tange K, Nakai Y, Yoshioka H, Harashima H, Akita H.
    • Journal Title

      Mol Pharm.

      Volume: 15 Pages: 2060-2067

    • DOI

      10.1021/acs.molpharmaceut.7b01084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-17K19473
  • [Journal Article] Cancer-type organic anion transporting polypeptide 1B3 is a target for cancer suicide gene therapy using RNA trans-splicing technology.2018

    • Author(s)
      Sun Y, Pinon Hofbauer J, Harada M, Woss K, Koller U, Morio H, Stierschneider A, Kitamura K, Hashimoto M, Chiba K, Akita H, Anzai N, Reichelt J, Bauer JW, Guttmann-Gruber C, Furihata T.
    • Journal Title

      Cancer Letters

      Volume: 433 Pages: 107-116

    • DOI

      10.1016/j.canlet.2018.06.032

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19475
  • [Journal Article] Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics.2017

    • Author(s)
      Sato Y, Sakurai Y, Kajimoto K, Nakamura T, Yamada Y, Akita H, Harashima H.
    • Journal Title

      Macromolecular Biosciences

      Volume: 17 Pages: 1-16

    • DOI

      10.1002/mabi.201600179

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26282132, KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-26670741, KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-16K11180
  • [Journal Article] Temperature and pH sensitivity of stabilized self-nanoemulsion formed using an ionizable lipid-like material via an oil-to-surfactant transition2017

    • Author(s)
      Tanaka H, Oasa S, Kinjo M, Tange K, Nakai Y, Harashima H, Akita H
    • Journal Title

      Colloids and Surfaces B: Biointerfaces

      Volume: 151 Pages: 95-101

    • DOI

      10.1016/j.colsurfb.2016.11.020

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H01806, KAKENHI-PROJECT-14J02588, KAKENHI-PROJECT-15K14934
  • [Journal Article] Modifying Antigen-Encapsulating Liposomes with KALA Facilitates MHC Class I Antigen Presentation and Enhances Anti-tumor Effects2017

    • Author(s)
      Miura N, Akita H, Tateshita N, Nakamura T, Harashima H.
    • Journal Title

      Molecular Therapy

      Volume: 印刷中 Pages: 1003-1013

    • DOI

      10.1016/j.ymthe.2017.01.020

    • NAID

      120006425607

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H01806, KAKENHI-PROJECT-15J01221
  • [Journal Article] Cellular environment-responsive nanomaterials for use in gene and siRNA delivery: molecular design for biomembrane destabilization and intracellular collapse2016

    • Author(s)
      Tanaka H, Sato Y, Harashima H, Akita H
    • Journal Title

      Expert Opin Drug Deliv.

      Volume: 13(7) Pages: 1015-1027

    • DOI

      10.1517/17425247.2016.1154531

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H01806, KAKENHI-PROJECT-15K14934
  • [Journal Article] Identification of a Nucleoporin358-Specific RNA Aptamer for Use as a Nucleus-Targeting Liposomal Delivery System.2016

    • Author(s)
      Shrivastava G, Hyodo M, Yoshimura SH, Akita H, Harashima H
    • Journal Title

      Nucleic Acid Ther

      Volume: 26(5) Pages: 286-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Journal Article] Cellular environment-responsive nanomaterials for use in gene and siRNA delivery: molecular design for biomembrane destabilization and intracellular collapse.2016

    • Author(s)
      Tanaka H, Sato Y, Harashima H, Akita H.
    • Journal Title

      Expert Opin Drug Deliv

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Journal Article] Transcytosis Targeting Peptide: A Conductor of Liposomal Nanoparticles through the Endothelial Cell Barrier2016

    • Author(s)
      Akita H, Fujiwara T, Santiwarangkool S, Hossen N, Kajimoto K, El-Sayed A, Tabata Y, Harashima H.
    • Journal Title

      Small

      Volume: 12 Pages: 1212-1221

    • DOI

      10.1002/smll.201500909

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H01806, KAKENHI-PROJECT-26282132
  • [Journal Article] Cellular environment-responsive nanomaterials for use in gene and siRNA delivery: molecular design for biomembrane destabilization and intracellular collapse.2016

    • Author(s)
      Tanaka H, Sato Y, Harashima H, Akita H.
    • Journal Title

      Expert Opin Drug Deliv.

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K14934
  • [Journal Article] Effect of particle size on thier accumulation in an inflammatory lesion in a dextran sulfate sodium (DSS)-induced colitis model2016

    • Author(s)
      Watanabe A, Tanaka H, Sakurai Y, Tange K, Nakai Y, Ohkawara T, Takeda H, Harashima H, Akita H.
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 509(1-2) Pages: 118-122

    • DOI

      10.1016/j.ijpharm.2016.05.043

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H01806, KAKENHI-PROJECT-14J02588, KAKENHI-PROJECT-15K14934
  • [Journal Article] Effect of hydrophobic scaffold on the cellular uptake and gene transfection activities of DNA-encapsulating liposomal nanoparticles via intracerebroventricular administration.2015

    • Author(s)
      Akita H, Nakatani T, Kuroki K, Maenaka K, Tange K, Nakai Y, Harashima H.
    • Journal Title

      Int J Pharm

      Volume: 490 Pages: 142-145

    • DOI

      10.1016/j.ijpharm.2015.05.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Journal Article] Effect of the Compaction and the Size of DNA on the Nuclear Transfer Efficiency after Microinjection in Synchronized Cells2015

    • Author(s)
      Akita H, Kurihara D, Schmeer M, Schleef M, Harashima H.
    • Journal Title

      Pharmaceutics

      Volume: 7 Pages: 64-73

    • DOI

      10.3390/pharmaceutics7020064

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Journal Article] Molecular Tuning of a Vitamin E-Scaffold pH-Sensitive and Reductive Cleavable Lipid-like Material for Accelerated in Vivo Hepatic siRNA Delivery2015

    • Author(s)
      Akita, H. Noguchi Y, Hatakeyama H, Tange K, Nakai Y, Harashima H
    • Journal Title

      ACS Biomater Sci Eng

      Volume: 1 Pages: 834-844

    • DOI

      10.1021/acsbiomaterials.5b00203

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14934, KAKENHI-PROJECT-15H01806
  • [Journal Article] Particle tracking analysis for the intracellular trafficking of nanoparticles modified with African swine fever virus protein p54-derived peptide2013

    • Author(s)
      Akita H, Enoto K, Tanaka H, Harashima H
    • Journal Title

      Molecular Therapy

      Volume: 21(2) Pages: 309-317

    • DOI

      10.1038/mt.2012.235

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Journal Article] A multifunctional envelope-type nano device for use in nanomedicine: concept and Applications.2012

    • Author(s)
      Nakamura T, Akita H, Yamada Y, Hatakeyama H, Harashima H
    • Journal Title

      Accounts of Chemical Research

      Volume: 45(7) Pages: 1113-1121

    • DOI

      10.1021/ar200254s

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001, KAKENHI-PUBLICLY-24107502
  • [Journal Article] Effect of the Anchor in Polyethylene Glycol-Lipids on the Transfection Activity of PEGylated Cationic Liposomes Encapsulating DNA2012

    • Author(s)
      Kusumoto K, Akita H, El-Sayed A, Harashima H
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 35(4) Issue: 4 Pages: 445-448

    • DOI

      10.1248/bpb.35.445

    • NAID

      130001872189

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10F00421, KAKENHI-PROJECT-22229001
  • [Journal Article] Stearylated INF7 Peptide enhances endosomal escape and gene expression of PEGylated nanoparticles both in vitro and in vivo2012

    • Author(s)
      El-Sayed A, Masuda T, Akita H, Harashima H
    • Journal Title

      J Pharm Sci

      Volume: 101(2) Pages: 879-882

    • DOI

      10.1002/jps.22807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10F00421, KAKENHI-PROJECT-22229001
  • [Journal Article] Cell penetrating peptide-mediated systemic siRNA delivery to the liver.2011

    • Author(s)
      Hayashi Y, Yamauchi J, Khalil IA, Kajimoto K, Akita H, Harashima H
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 419(1-2) Pages: 308-13

    • DOI

      10.1016/j.ijpharm.2011.07.038

    • NAID

      120003504743

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001, KAKENHI-PROJECT-23790038
  • [Journal Article] Quantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET.2011

    • Author(s)
      Shaheen SM, Akita H, et al
    • Journal Title

      H.Nucleic Acids Res.

      Volume: (印刷中)

    • NAID

      120002989236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659006
  • [Journal Article] Improving in Vivo Hepatic Transfection Activity by Controlling Intracellular Trafficking : The Function of GALA and Maltotriose2011

    • Author(s)
      Akita H, Masuda T, Nishio T, Niikura K, Ijiro K, Harashima H
    • Journal Title

      Mol.Pharmaceutics

      Volume: 8(4) Pages: 1436-1442

    • DOI

      10.1021/mp200189s

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001, KAKENHI-PROJECT-22350076, KAKENHI-PROJECT-22655050, KAKENHI-PROJECT-22655059
  • [Journal Article] KALA-modified multi-layered nano- particles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine2011

    • Author(s)
      Shaheen SM, Akita H, Nakamura T, Takayama S, Futaki S, Yamashita A, Katoono R, Yui N, Harashima H
    • Journal Title

      Biomaterials

      Volume: 32(26) Pages: 6342-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659006
  • [Journal Article] Functional improvement of an I.RQ-PEG-MEND for delivering genes to the lung2011

    • Author(s)
      Ishitsuka T, Akita H, Harashima H
    • Journal Title

      J Control Release

      Volume: 154(1) Pages: 77-83

    • DOI

      10.1016/j.jconrel.2011.05.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Journal Article] Dual imaging of mRNA and protein production : an investigation of the mechanism of heterogeneity in cationic lipid-mediated transgene expression2011

    • Author(s)
      Akita H, Umetsu Y, Kurihara D, Harashima H
    • Journal Title

      Int J Pharm

      Volume: 415(1-2) Pages: 218-220

    • DOI

      10.1016/j.ijpharm.2011.05.051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Journal Article] KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine2011

    • Author(s)
      Shaheen SM, Akita H, Nakamura T, Takayama S, Futaki S, Yamashita A, Katoono R, Yui N, Harashima H
    • Journal Title

      Biomaterials

      Volume: 32(26) Pages: 6342-6350

    • DOI

      10.1016/j.biomaterials.2011.05.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001, KAKENHI-PROJECT-22659006
  • [Journal Article] A DNA Microarray-based Analysis of the Host Response to a Nonviral Gene Carrier: A Strategy for Improving the Immune Response2011

    • Author(s)
      Hatakeyama H, Ito E, Yamamoto M, Akita H, Hayashi Y, Kajimoto K, Kaji N, Baba Y, Harashima H
    • Journal Title

      Mol Ther

      Volume: 19(8) Pages: 1487-98

    • NAID

      120003762627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659006
  • [Journal Article] Intracellular fate of octaarginine-modified liposomes in polarized MDCK cells2010

    • Author(s)
      Fujiwara T, Akita H, Harashima H.
    • Journal Title

      Int J Pharm 386

      Pages: 122-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines : Programmed endosomal escape and dissociation2010

    • Author(s)
      Akita H, Kogure K, Moriguchi R, Nakamura Y, Higashi T, Nakamura T, Serada S, Fujimoto M, Naka T, Futaki S, Harashima H.
    • Journal Title

      J Control Release. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Intracellular fate of octaarginine- modified liposomes in polarized MDCK cells.2010

    • Author(s)
      T.Fujiwara, H.Akita, H.Harashima
    • Journal Title

      Int J Pharm 386

      Pages: 122-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines : Programmed endosomal escape and dissociation2010

    • Author(s)
      Akita H, et al.
    • Journal Title

      J.Cont.Rel. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Journal Article] Intracellular fate of octaarginine-modified liposomes in polarized MDCK cells.2010

    • Author(s)
      Fujiwara T, Akita H, Harashima H.
    • Journal Title

      Int J Pharm 386

      Pages: 122-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20650072
  • [Journal Article] Leptin-derived peptide, a targeting ligand for mouse brain-derived endothelial cells via macropinocytosis.2010

    • Author(s)
      Tamaru M, Akita H, Fujiwara T, Kajimoto K, Harashima H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 394(3) Pages: 311-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689002
  • [Journal Article] Particle Tracking of Intracellular Trafficking of Octaarginine-modified Liposomes : A Comparative Study With Adenovirus2010

    • Author(s)
      Akita H, Enoto K, Masuda T, Mizuguchi H, Tani T, Harashima H.
    • Journal Title

      Mol Ther (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Leptin-derived peptide, a targeting ligand for mouse brain-derived endothelial cells via macropinocytosis.2010

    • Author(s)
      Tamaru M, Akita H, Fujiwara T, Kajimoto K, Harashima H.
    • Journal Title

      Biochem Biophys Res Commun. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20650072
  • [Journal Article] Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancervaccines : Programmed endosomal escape and dissociation.2010

    • Author(s)
      Akita H, Kogure K, et al
    • Journal Title

      J Control Release.

      Volume: 143 Pages: 311-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Journal Article] Particle Tracking of Intracellular Trafficking of Octaarginine-modified Liposomes : A Comparative Study With Adenovirus.2010

    • Author(s)
      Akita H, Enoto K, Masuda T, Tani T, Mizuguchi H, Harashima H
    • Journal Title

      Mol Ther

      Volume: 18(5) Pages: 955-964

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689002
  • [Journal Article] Envelope-type lipid nanoparticles incorporating a short PEG-lipid conjugate for improved control of intracellular trafficking and transgene transcription2009

    • Author(s)
      Masuda, T., Akita, H., Niikura, K., Nishio, T., Ukawa, M., Enoto, K., Danev, R., Nagayama, K., Ijiro, K., Harashima, H
    • Journal Title

      Biomaterials 30

      Pages: 4806-4814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Enhanced gene expression by a novel stearylated INF7 peptide derivative through fusion independent endosomal escape.2009

    • Author(s)
      El-Sayed A, Masuda T, Khalil I, Akita H, Harashima H.
    • Journal Title

      J Control Release. 138(2)

      Pages: 160-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Journal Article] Novel Lipidated Sorbitol-based Molecular Transporters for Non-viral Gene Delivery2009

    • Author(s)
      Higashi T, Khalil IA, Maiti KK, Lee WS, Akita H, Harashima H, Chung SK.
    • Journal Title

      J Control Release (in press)

    • NAID

      120001390961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Multi-layered nano particles for penetrating the endosome and nuclear membrane via a steo-wise membrane fusion process.2009

    • Author(s)
      H.Akita, A.Kudo, A.Minoura, M.Yamaguchi, IA.Khalil, R.Moriguchi, T.Masuda, R.Danev, K.Nagayama, K.Kogure, H.Harashima
    • Journal Title

      Biomaterials 30

      Pages: 2940-2949

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Journal Article] A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.2009

    • Author(s)
      H.Hatakeyama, E.Ito, H.Akita, M.Oishi, Y.Nagasaki, S.Futaki, H.Harashima
    • Journal Title

      J.Control.Release 139

      Pages: 127-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Journal Article] Multilayered nano particles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process2009

    • Author(s)
      H. Akita, A. Kudo, A. Minoura, M. Ya maguchi, I. A Khalil, R. Moriguchi, T. Masuda, R. Danev, K. Nagayama, K. Ko gure and H. Harashima.
    • Journal Title

      Biomaterials (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Multi-layered nano particles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process.2009

    • Author(s)
      H. Akita, A. Kudo, A. Minoura, M. Yamaguchi, I. A Khalil, R. Moriguchi, T. Masuda, R. Danev, K. Nagayama, K. Kogure, H. Harashima
    • Journal Title

      Biomaterials 30(15)

      Pages: 2940-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Journal Article] Efficient siRNA delivery to tumor cells using the combination of octaarginine, GALA and tumor-specific, cleavable PEG system.2009

    • Author(s)
      Y.Sakurai, H.Hatakeyama, H.Akita, M.Oishi, Y.Nagasaki, S.Futaki, H.Harashima
    • Journal Title

      Biol.Pharm.Bull. 32

      Pages: 928-932

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Journal Article] Envelope-type lipid nanoparticles incorporating a short PEG-lipid conjugate for improved control of intracellular trafficking and transgene transcription.2009

    • Author(s)
      T.Masuda, H.Akita, K.Niikura, T.Nishio, M.Ukawa, K.Enoto, R.Danev, K.Nagayama, K.Ijiro, H.Harashima
    • Journal Title

      Biomaterials 30

      Pages: 4806-4814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Multi-layered nano particles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process.2009

    • Author(s)
      H.Akita, A.Kudo, A.Minoura, M.Yamaguchi, I.A Khalil, R.Moriguchi, T.Masuda, R.Danev, K.Nagayama, K.Kogure, H.Harashima
    • Journal Title

      Biomaterials 30

      Pages: 2940-2949

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Multi-layered nano particles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process.2009

    • Author(s)
      H.Akita, et al.
    • Journal Title

      Biomaterials 30(15)

      Pages: 2940-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Journal Article] Envelope-type lipid nanoparticles incorporating a short PEG-lipid conjugate for improved control of intracellular trafficking and transgene transcription.2009

    • Author(s)
      Masuda T, Akita H, Niikura K, Nishio T, Ukawa M, Enoto K, Danev R, Nagayama K, Ijiro K, Harashima H.
    • Journal Title

      Biomaterials 30(27)

      Pages: 4806-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Journal Article] Multi-layered nano particles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process2009

    • Author(s)
      H. Akita, A. Kudo, A. Minoura, M. Yamaguchi, I. A. Khalil, R. Moriguchi, T. Masuda, R. Danev, K. Nagayama, K. Kogure and H. Harashima.
    • Journal Title

      Biomaterials 30(15)

      Pages: 2940-9

    • Data Source
      KAKENHI-PROJECT-18200032
  • [Journal Article] Development of lipid particles targeted via sugar-lipid conjugates as novel nuclear gene delivery system2008

    • Author(s)
      T. Masuda, H. Akita, T. Nishio, K. Niikura, K. Kogure, K. Ijiro, H. Harashima.
    • Journal Title

      Biomaterials 29

      Pages: 709-723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] A novel IRQ ligand-modified nano-carrier targeted to a unique pathway of caveolar endocytic pathway.2008

    • Author(s)
      D. Mudhakir, H. Akita, E. Tan, H. Harashima
    • Journal Title

      J Control Release 125(2)

      Pages: 164-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Journal Article] Development of lipid particles targeted via sugar-lipid conjugates as novel nuclear gene delivery system.2008

    • Author(s)
      T.Masuda, H.Akita, T.Nishio, K.Niikura, A.Kudo, K.Kogure, K.Ijiro, H.Harashima
    • Journal Title

      Biomaterials 29

      Pages: 709-723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] A novel IRQ ligand-modified nano-carrier targeted to a unique pathway of caveolar endocytic pathway2008

    • Author(s)
      Diky Mudhakir, H. Akita, E. Tan, H. Harashima.
    • Journal Title

      J Controlled Rel 125

      Pages: 164-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Oligosaccharide-Mediated Nuclear Transport of Nanoparticles2008

    • Author(s)
      K. Niikura, S. Sekiguchi, T. Nishio, T. Masuda, H. Akita, Y. Matsuo, K.Kogure, H. Harashima. K. Iiiro
    • Journal Title

      Chembiochem 9

      Pages: 2623-2627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Photosensitized breakage and damage of DNA by CdSe-ZnS quantum dots2008

    • Author(s)
      Anas A, Akita H, Harashima H, Itoh T, Ishikawa M, Biju. V.
    • Journal Title

      J Phys Chem B 112

      Pages: 10005-10011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021003
  • [Journal Article] Advances in non-viral gene delivery : using multifunctional envelope-type nano device2008

    • Author(s)
      H. Akita and H. Harashima.
    • Journal Title

      Expert Opinion on Drue Delivery 5

      Pages: 847-859

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20650072
  • [Journal Article] MITO-Porter: a liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion2008

    • Author(s)
      Y. Yamada, H. Akita, H. Kamiya, K. Kogure, T. Yamamoto, Y. Shinohara, K. Yamashita, H. Kobayashi, H. Kikuchi, and H. Harashima
    • Journal Title

      Biochim. Biophys. Acra (In press)

    • NAID

      120000952609

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390034
  • [Journal Article] MITO-Porter: a liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion.2008

    • Author(s)
      Y. Yamada, H. Akita, H. Kamiya, K. Kogure, T. Yamamoto, Y. Shinohara, K. Yamashita, H. Kobayashi, H. Kikuchi, and H. Harashima
    • Journal Title

      Biochim. Biophys. Acta. (In press)

    • NAID

      120000952609

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390034
  • [Journal Article] A novel IRQ ligand-modified nano-carrier targeted to a unique pathway of caveolar endocytic pathway2008

    • Author(s)
      D.Mudhakir, H.Akita, E.Tan, H.Harashima
    • Journal Title

      J Controlled Rel. 125(2)

      Pages: 164-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Supramolecular control of polyplex dissociation and cell transfection : efficacy of amino groups and threading cyclodextrins in biocleavable polyrotaxanes2008

    • Author(s)
      Yamashita A, Kinda D, Katoono R, Yui N, Ooya T, Maruyama A, Akita H, Kogure K, Harashima H.
    • Journal Title

      J Control Release 131

      Pages: 137-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021003
  • [Journal Article] Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex.2007

    • Author(s)
      S. Hama, H. Akita, S. Iida, H. Mizuguchi and H. Harashima
    • Journal Title

      Nucl. Acids Res. 35

      Pages: 1533-1543

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390034
  • [Journal Article] Octaarginine-modified envelope-type nanoparticles for gene delivery. Gene Therapy nanoparticles for gene delivery2007

    • Author(s)
      I. A. Khalil, K. Kogure, S. Futaki, S. Hama, H. Akita, K. Kataoka, and H. Harashima
    • Journal Title

      Gene Therapy 14(8)

      Pages: 682-9

    • Data Source
      KAKENHI-PROJECT-18200032
  • [Journal Article] Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex2007

    • Author(s)
      S. Hama, H. Akita, S. Iida, H. Mizuguchi and H. Harashima
    • Journal Title

      Nucl. Acids Res. 35

      Pages: 1533-1543

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390034
  • [Journal Article] Cell-cycle dependent transcription, a determinant factor of heterogeneity in cationic lipid-mediated transgene expression2007

    • Author(s)
      H. Akita, R. Ito, H. Kamiya, K. Kogure, and H. Harashima:
    • Journal Title

      J. Gene Med 9

      Pages: 197-207

    • NAID

      120000973870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021003
  • [Journal Article] Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex.2007

    • Author(s)
      S.Hama, H.Akita, S.Iida, H.Mizuguchi, H.Harashima
    • Journal Title

      Nucleic Acids Res. 35

      Pages: 1533-1543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex.2007

    • Author(s)
      Hama S, Akita H, Mizuguchi H, Hayakawa Y, Harashima H
    • Journal Title

      Nucleic Acids Res (In press)

    • Data Source
      KAKENHI-PROJECT-17790110
  • [Journal Article] Cell cycle- dependent transcription, a determinant factor of heterogeneity in cationic lipid-mediated transgene expression.2007

    • Author(s)
      H. Akita, R. Ito, H. Kamiya, K. Kogure, and H. Harashima
    • Journal Title

      J. Gene Med. 9

      Pages: 197-207

    • NAID

      120000973870

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390034
  • [Journal Article] Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex.2007

    • Author(s)
      Hama S, Akita H, Mizuguchi H, Hayakawa Y, Harashima H
    • Journal Title

      Nucleic Acids Res (In press)

    • Data Source
      KAKENHI-PROJECT-18038001
  • [Journal Article] Cell-cycle dependent transcription, a determinant factor of heterogeneity in cationic lipid-mediated transgene expression2007

    • Author(s)
      H.Akita, R.Ito, H.Kamiya, K.Kogure, H.Harashima
    • Journal Title

      J. Gene Med. (in press)

    • NAID

      120000973870

    • Data Source
      KAKENHI-PROJECT-18390034
  • [Journal Article] Cell cycle dependent transcription, a determinant factor of heterogeneity in cationic lipid-mediated transgene expression2007

    • Author(s)
      H. Akita, R. Ito, H. Kamiya, K. Kogure, and H. Harashima
    • Journal Title

      J. Gene Med. 9

      Pages: 197-207

    • NAID

      120000973870

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390034
  • [Journal Article] Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems.2006

    • Author(s)
      Hama S, Akita H, Mizuguchi H, Hayakawa Y, Harashima H
    • Journal Title

      Mol Ther 13(4)

      Pages: 786-794

    • Data Source
      KAKENHI-PROJECT-17790110
  • [Journal Article] Evaluation of the nuclear delivery and intra-nuclear transcription of the plasmid DNA condensed with m (mu) and NLS-m by cytoplasmic and nuclear microinjection : comparative study with poly L-lysine.2006

    • Author(s)
      H.Akita
    • Journal Title

      J. Gen.Med. 8・2

      Pages: 198-206

    • Data Source
      KAKENHI-PROJECT-18015004
  • [Journal Article] Development of efficient packaging method of oligodeoxynucleotides by a condensed nano particle in lipid envelope structure.2005

    • Author(s)
      Y.Yamada, K.Kogure, Y.Nakamura, K.Inoue, H.Akita, F.Nagatsugi, S.Sasaki, T.Suhara, H.Harashima
    • Journal Title

      Biol Pharm Bull 28

      Pages: 1939-1942

    • NAID

      110003666368

    • Data Source
      KAKENHI-PROJECT-17790110
  • [Journal Article] Sunflower-shaped cyclodextrin-conjugated poly(epsilon-lysine) polyplex as a controlled intracellular trafficking device.2005

    • Author(s)
      H.S.Choi, A.Yamashita, T.Ooya, N.Yui, H.Akita, K.Kogure, R.Ito, H.Harashima.
    • Journal Title

      Chembiochem 6

      Pages: 1986-1990

    • Data Source
      KAKENHI-PROJECT-17790110
  • [Journal Article] Development of an efficient method for packaging oligodeoxynucleotides in a condensed nano particle with a lipid-envelope structure.2005

    • Author(s)
      Y.Yamada, K.Kogure, Y.Nakamura, K.Inoue, H.Akita, F.Ngatsugi, S.Sasaki, T.Suhara, H.Harashima.
    • Journal Title

      Biol. Pharm. Bull. 28・10

      Pages: 1939-1942

    • Data Source
      KAKENHI-PROJECT-17659039
  • [Journal Article] Evaluation of nuclear transfer and transcription of plasmid DNA condensed with protamine by microinjection : the use of a nuclear transfer score.2005

    • Author(s)
      T.Masuda, H.Akita, H.Harashima
    • Journal Title

      FEBS Lett 579

      Pages: 2143-2148

    • Data Source
      KAKENHI-PROJECT-17790110
  • [Journal Article] A multifunctional envelope-type nano device for novel gene delivery of siRNA plasmids2005

    • Author(s)
      R.Moriguchi, K.Kogure, H.Akita, S.Futaki, M.Miyagishi, K.Taira, H.Harashima
    • Journal Title

      Int J Pharm 301

      Pages: 277-285

    • Data Source
      KAKENHI-PROJECT-17790110
  • [Journal Article] Pharmacokinetic analysis of the tissue distribution of octaarginine modified liposomes in mice2005

    • Author(s)
      D.Mudhakir, H.Akita, I.A.Khalil, S.Futaki, H.Harashima
    • Journal Title

      Drug Metab Pharmacokinet 20

      Pages: 275-281

    • NAID

      130004933331

    • Data Source
      KAKENHI-PROJECT-17790110
  • [Journal Article] Quantitative three-dimesional analysis of the intracellular trafficking of plasmid DNA transfected by non-viral gene delivery system using con focal laser scanning microscopy.2004

    • Author(s)
      H.Akita
    • Journal Title

      Mol.Ther. 9

      Pages: 443-451

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300151
  • [Journal Article] Quantitative three-dimesional analysis of the intracellular trafficking of plasmid DNA transfected by non-viral gene delivery system using confocal laser scanning microscopy.2004

    • Author(s)
      H.Akita
    • Journal Title

      Mol.Ther. 9

      Pages: 443-451

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300151
  • [Journal Article] Quantitative three dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivary system using confocal laser scanning microscopy2004

    • Author(s)
      Akita H, Ito R, Khalil I, Futaki S, Harashima H
    • Journal Title

      Mol Ther 9(3)

      Pages: 443-450

    • Data Source
      KAKENHI-PROJECT-15790084
  • [Journal Article] Pharmacokinetic and pharmacodynamic considerations in gene therapy2003

    • Author(s)
      Kamiya H, Akita H, Harashima H
    • Journal Title

      Drug Discovery Today 18(21)

      Pages: 990-996

    • Data Source
      KAKENHI-PROJECT-15790084
  • [Journal Article] Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines

    • Author(s)
      H.Akita, K.Kogure, R.Moriguchi, Y.Nakamura, T.Higashi, T.Nakamura, S.Serada, M.Fujimoto, T.Naka, S.Futaki, H.Harashima
    • Journal Title

      Programmed endosomal escape and dissociation (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article] Multi-layered nano particles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process

    • Author(s)
      H. Akita
    • Journal Title

      Biomaterials (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Journal Article] Particle Tracking of Intracellular Trafficking of Octaarginine-modified Liposomes: A Comparative Study With Adenovirus.

    • Author(s)
      H.Akita, K.Enoto, T, Masuda, H.Mizuguchi, T.Tani, H.Harashima
    • Journal Title

      Mol Ther. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Journal Article]

    • Author(s)
      H.Akita, K.Kogure, R.Moriguchi, Y.Nakamura, T.Higashi, T.Nakamura, S.Serada, M.Fujimoto, T.Naka, S.Futaki, H.Harashima
    • Journal Title

      J.Control.Release (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Patent] 細胞内動態を改善した新規カチオン性脂質2018

    • Inventor(s)
      秋田英万、田中浩揮、高田奈依、高橋達也、小西真奈美
    • Industrial Property Rights Holder
      秋田英万、田中浩揮、高田奈依、高橋達也、小西真奈美
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Patent] 組換え発現ベクター及び当該ベクターを封入した脂質膜構造体2016

    • Inventor(s)
      原島秀吉, 山田勇磨, 石川卓哉, 秋田英万
    • Industrial Property Rights Holder
      国立大学法人 北海道大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-11-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26282131
  • [Patent] 組換え発現ベクター及び当該ベクターを封入した脂質膜構造体2015

    • Inventor(s)
      原島秀吉、山田勇磨、石川卓哉、秋田英万
    • Industrial Property Rights Holder
      国立大学法人北海道大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-230498
    • Filing Date
      2015-11-26
    • Data Source
      KAKENHI-PROJECT-26282131
  • [Patent] O/W型エマルション2015

    • Inventor(s)
      原島秀吉、秋田英万、田中浩揮など
    • Industrial Property Rights Holder
      原島秀吉、秋田英万、田中浩揮など
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-200148
    • Filing Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Patent] O/W型エマルション2015

    • Inventor(s)
      原島秀吉、秋田英万、田中浩揮、渡邊綾香など7名
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-200148
    • Filing Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K14934
  • [Patent] 結合剤およびその利用2012

    • Inventor(s)
      原島秀吉、林泰弘、秋田英万、鳥谷部尚之、富樫亮平
    • Industrial Property Rights Holder
      原島秀吉、林泰弘、秋田英万、鳥谷部尚之、富樫亮平
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-174272
    • Filing Date
      2012-08-06
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Patent] 核移行性を有する脂質膜構造体2011

    • Inventor(s)
      原島秀吉、秋田英万、シャリフモハメドシャヒーン、中村孝司、石井聡一郎、二木史朗
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2011-04-10
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22659006
  • [Patent] 核内移行性を有する脂質膜構造体2011

    • Inventor(s)
      原島秀吉, 秋田英万、シャリフモハメドシャヒーン、中村孝司、石井聡一郎、二木史朗
    • Industrial Property Rights Holder
      原島秀吉,秋田英万、シャリフモハメドシャヒーン、中村孝司、石井聡一郎、二木史朗
    • Filing Date
      2011-04-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Patent] 肺送達のためのベクター、導入剤及び使用2011

    • Inventor(s)
      秋田英万、楠本憲司、原島秀吉、畠山浩人、石塚太一
    • Industrial Property Rights Holder
      大鵬薬品工業株式会社
    • Industrial Property Number
      2011-055765
    • Filing Date
      2011-03-14
    • Data Source
      KAKENHI-PROJECT-22689002
  • [Patent] 細胞内動態を改善したカチオン性脂質2011

    • Inventor(s)
      丹下耕太、新井将也、久保和弘、秋田英万、原島秀吉、畠山浩人、石破諒平、鵜川真実
    • Industrial Property Rights Holder
      丹下耕太、新井将也、久保和弘、秋田英万、原島秀吉、畠山浩人、石破諒平、鵜川真実
    • Industrial Property Number
      2011-252309
    • Filing Date
      2011-11-18
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Patent] 核内移行性を有する脂質膜構造体2011

    • Inventor(s)
      原島秀吉,秋田英万、シャリフモハメドシャヒーン、中村孝司、石井聡一郎、二木史朗、権利者
    • Filing Date
      2011-04-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22659006
  • [Patent] 機能性ポリペプチド及び当該ポリペプチドで修飾された脂質膜構造体2010

    • Inventor(s)
      原島秀吉、秋田英万、榎戸薫、畠山浩人、櫻井遊
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2010-039667
    • Filing Date
      2010-02-25
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] 機能性ポリペプチド及び当該ポリペプチドで修飾された脂質膜構造体2010

    • Inventor(s)
      原島秀吉, 秋田英万, 畠山浩人, 他
    • Industrial Property Rights Holder
      国立大学法人北海道大学
    • Industrial Property Number
      2010-039667
    • Filing Date
      2010-02-25
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Patent] 機能性ポリペプチドお呼び当該ポリペプチドで就職された脂質膜構造体2010

    • Inventor(s)
      原島秀吉, 秋田英万、榎戸薫、畠山浩人、桜井遊
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2010-02-25
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Patent] 高分子化合物またはその複合体の細胞透過性評価装置及びその細胞透過性評価方法.2009

    • Inventor(s)
      原島秀吉, 秋田英万、藤原孝博、田畑泰彦
    • Industrial Property Rights Holder
      北海道大学、京都大学
    • Filing Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Patent] 脂質膜構造体に細胞透過能を付与するペプチド、およびそれらペプチドと結合した脂質を構成脂質として含む、細胞透過能を有する脂質膜構造体2009

    • Inventor(s)
      秋田英万、藤原孝博、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-283091
    • Filing Date
      2009-12-14
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] 脂質膜構造体2009

    • Inventor(s)
      原島秀吉, 秋田英万、アイマンエルサイド、増田智也
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2009-03-23
    • Data Source
      KAKENHI-PROJECT-20659020
  • [Patent] 脂質膜構造体2009

    • Inventor(s)
      原島秀吉, 秋田英万、アイマンエルサイド、増田智也
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2009-03-23
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Patent] 脂質膜構造体に細胞透過能を付与するペプチド、およびそれらペプチドと結合した脂質を構成脂質として含む、細胞透過能を有する脂質膜構造体2009

    • Inventor(s)
      秋田英万、藤原孝博、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-283091
    • Filing Date
      2009-12-14
    • Data Source
      KAKENHI-PROJECT-20650072
  • [Patent] 核輸送性脂質膜構造体2009

    • Inventor(s)
      原島秀吉, 秋田英万, 増田智也, 新倉謙一, 西尾崇, 居城邦治
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-069438
    • Filing Date
      2009-03-23
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] 高分子化合物またはその複合体の細胞透過性評価装置およびその細胞透過性評価方法2009

    • Inventor(s)
      秋田英万、藤原孝博、田畑泰彦、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-275877
    • Filing Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-20650072
  • [Patent] 高分子化合物またはその複合体の細胞透過性評価装置およびその細胞透過性評価方法2009

    • Inventor(s)
      秋田英万、藤原孝博、田畑泰彦、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-275877
    • Filing Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] 核輸送性脂質膜構造体2009

    • Inventor(s)
      原島秀吉, 増田智也、秋田英万、西尾崇、新倉謙一、居城邦治
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2009-03-23
    • Data Source
      KAKENHI-PROJECT-20659020
  • [Patent] 脂質膜構造体2009

    • Inventor(s)
      原島秀吉, 秋田英万、アイマンエルサイド、増田智也
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2009-03-23
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Patent] 脂質膜構造体に細胞透過能を付与するペプチドと結合した脂質を構成脂質として含む、細胞透過能を有する脂質膜構造体.2009

    • Inventor(s)
      原島秀吉, 秋田英万、藤原孝博
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2009-12-14
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Patent] 生体内で機能する核輸送性脂質膜構造体2009

    • Inventor(s)
      秋田英万、増田智也、西尾崇、新倉謙一、居城邦治、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-069438
    • Filing Date
      2009-03-23
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] オリゴアルキレングリコール修飾された脂質膜構造体2009

    • Inventor(s)
      秋田英万、増田智也、居城邦治、新倉謙一、西尾崇、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2009-04-24
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] オリゴアルキレングリコール修飾された脂質膜構造体2008

    • Inventor(s)
      秋田英万、増田智也、居城邦治、新倉謙一、西尾崇、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2008-115388
    • Filing Date
      2008-04-25
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] 腫瘍組織で選択的に分解性を示す血中滞留性素子2008

    • Inventor(s)
      秋田英万, 畠山浩人, 原島秀吉
    • Industrial Property Rights Holder
      国立大学法人北海道大学
    • Filing Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-20015003
  • [Patent] リポソーム用生体成分抵抗性増強剤及びこれにより修飾されたリポソーム2008

    • Inventor(s)
      小暮健太朗、秋田英万、岩朝亮忠、中村宜夫、二木史朗、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2008-02-27
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] 脂質膜構造体2008

    • Inventor(s)
      原島秀吉,増田智也、秋田英万、石原一彦、金野智浩
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Patent] オリゴアルキレングリコール修飾された脂質膜構造体2008

    • Inventor(s)
      原島秀吉,増田智也、秋田英万、居城邦治、新倉謙一、西尾崇
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2008-04-25
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Patent] リポソーム用生体成分抵抗性増強剤及びこれにより修飾されたリポソーム2007

    • Inventor(s)
      小暮健太朗、秋田英万、岩朝亮忠、中村宜夫、二木史朗、原島秀吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2007-085628
    • Filing Date
      2007-02-28
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Patent] 腫瘍選択的分解性を示す血中滞留性素子2007

    • Inventor(s)
      秋田 英万・畠山 浩人・長崎 幸夫・大石 基・菊池 寛・小林 英夫・原島 秀吉
    • Industrial Property Rights Holder
      北海道大学、筑波大学、塩野義製薬株式会社
    • Filing Date
      2007-07-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18015004
  • [Patent] 目的物質をミトコンドリア内に送達可能な脂質膜構造体2006

    • Inventor(s)
      山田勇磨, 秋田英万, 小暮健太朗, 紙谷浩之, 原島秀吉, 菊池寛, 小林英夫
    • Industrial Property Rights Holder
      北海道大学, 第一製薬株式会社
    • Filing Date
      2006-03-09
    • Data Source
      KAKENHI-PROJECT-17659039
  • [Patent] 目的物質をミトコンドリア内に送達可能な脂質膜構造体.2005

    • Inventor(s)
      山田 勇磨, 秋田 英万, 小暮 健太朗, 紙谷 浩之, 原島 秀吉, 菊池 寛, 小林 英夫
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2005-066385
    • Filing Date
      2005-03-09
    • Data Source
      KAKENHI-PROJECT-17659039
  • [Patent] 細胞に導入した核酸の標的オルガネラにおける局在量を定量する方法2003

    • Inventor(s)
      原島 秀吉, 秋田 英万
    • Industrial Property Rights Holder
      科学技術振興機構
    • Industrial Property Number
      2003-193038
    • Filing Date
      2003
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300151
  • [Presentation] Lymphatic microsurgeryにおけるリンパ節のドレナージ路の確保2020

    • Author(s)
      秋田新介 三川信之
    • Organizer
      第25回日本形成外科手術手技学会
    • Data Source
      KAKENHI-PROJECT-17K11529
  • [Presentation] How to maximize the effect of surgical treatment of lymphoedema2019

    • Author(s)
      Shinsuke Akita, Yoshihisa Yamaji, Nobuyuki Mitsukawa
    • Organizer
      第10回国際マイクロサージャリー学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11529
  • [Presentation] How to maximize the effect of surgical treatment of lymphoedema2019

    • Author(s)
      Akita S, Mitsukawa N
    • Organizer
      10th Congress of World Society for Reconstructive MIcrosurgery
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11529
  • [Presentation] Cytoplasmic delivery of exogenous IVT-mRNA using self-degradable lipid-like material.2018

    • Author(s)
      Hiroki Tanaka, Manami Konishi, Nae Takada, Tatsunari Takahashi, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Shinya Tamagawa, Hidetaka Akita
    • Organizer
      第20回武田科学振興財団生命科学シンポジウム RNAネオバイオロジー
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] 還元環境依存的な粒子内分解機構を搭載した自己崩壊型RNA送達システムの開発2018

    • Author(s)
      高田奈依、田中浩揮、高橋達成、小西真奈美、中井悠太、丹下耕太、吉岡宏樹、玉川晋也、秋田英万
    • Organizer
      日本核酸医薬学会第4回年会
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] 細胞内環境応答性材料ssPalmを基盤とした遺伝子・核酸デリバリーとイムノエンジニアリングへの応用2018

    • Author(s)
      秋田英万
    • Organizer
      第27回 日本癌転移学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] Intracellular environment-responsive material (ssPalm), as a technology for the DNA/RNA-based immune-engineering2018

    • Author(s)
      Hidetaka Akita
    • Organizer
      THE 12th SUGIYAMA LABORATORY (RIKEN) OPEN SYMPOSIUM
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] 凍結乾燥ワンポット法によるsiRNA 搭載型中性脂質ナノ粒子の開発と機能評価2018

    • Author(s)
      白根 大貴, 田中 浩揮, 丹下 耕太, 中井 悠太, 吉岡 宏樹, 秋田英万
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] 細胞内環境応答性脂質様材料を基盤とするin vivoメッセンジャーRNA送達システムの開発2018

    • Author(s)
      小西真奈美、田中浩揮、高橋達也、高田奈依、中井悠太、丹下耕太、吉岡宏樹、玉川晋也、秋田英万
    • Organizer
      第12回 次世代を担う若手医療薬科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] Development of RNA vaccine platform based on an intracellular environment-responsive lipid like material with vitamin E-scaffold2018

    • Author(s)
      Jessica Anndita、Naho Tateshita、Hiroki Tanaka、Naoya Miura, Yu Sakurai、Kota Tange 、Yuta Nakai、Hiroki Yoshioka、Hidetaka Akita
    • Organizer
      日本薬学会 第139年会
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] Development of DNA/RNA vaccine platform based on the intracellular environment-responsive lipid-like material2018

    • Author(s)
      Hidetaka Akita
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] Cancer-type organic anion transporting polypeptide 1B3 is a promising target for spliceosome-mediated RNA trans-splicing based suicide gene therapy2018

    • Author(s)
      Hanae Morio, Yuchen Sun, Manami Harada, Ulrich Koller, Anna Stierschneider, Josefina Pinon Hofbauer, Christina Gruber, Hidetaka Akita, Naohiko Anzai, Kan Chiba, Tomomi Furihata.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19475
  • [Presentation] Development of mRNA nanocarriers based on environment- responsive materials for the application to cancer vaccines2018

    • Author(s)
      Naho Tateshita, Hidetaka Akita
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] 凍結乾燥ワンポット法を用いたsiRNA搭載ナノ粒子の開発2018

    • Author(s)
      白根大貴、田中浩揮、櫻井遊、丹下耕太、中井悠太、吉岡宏樹、秋田英万
    • Organizer
      日本薬学会 第139年会
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] Development of self-hydrolyzable lipid-like material equipped with environment sensing motifs2018

    • Author(s)
      Hiroki Tanaka, Manami Konishi, Nae Takata, Tatunari, Takahashi, Yuta Nakai, Hiroki Yoshioka, Hidetaka Akita
    • Organizer
      18th Symposium for Gene, Design and Delivery
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19473
  • [Presentation] リンパ浮腫非侵襲評価方法の確立と侵襲的定量評価方法の開発2017

    • Author(s)
      秋田新介 山路佳久 窪田吉孝  手塚崇文 笹原資太郎 三川信之
    • Organizer
      第44回日本マイクロサージャリー学会
    • Data Source
      KAKENHI-PROJECT-17K11529
  • [Presentation] リンパ輸送能の定量評価を目的とした腹部リンパシステム可視化マウスモデルの作 成2017

    • Author(s)
      山路佳久 秋田新介 三川信之
    • Organizer
      第26回日本形成外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-17K11529
  • [Presentation] がん特異的遺伝子Cancer-type OATP1B3を標的としたRNA trans-splicing分子によるがん自殺遺伝子治療の基盤確立2017

    • Author(s)
      井手秀行、孫雨晨、原田まなみ、森尾花恵、秋田英万、Ulrich Koller、Anna Stierschneider、Josefina Pion Hofbauer、Christina Gruber、千葉寛、安西尚彦、降幡知巳
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-17K19475
  • [Presentation] A novel mouse model for visualized and quantitative assessment of lymphatic function using an in vivo imaging system2017

    • Author(s)
      Yoshihisa Yamaji, Shinsuke Akita, Nobuyuki Mitsukawa
    • Organizer
      26th World Congress of Lymphology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11529
  • [Presentation] がん特異的遺伝子産物cancer-type OATP1B3を標的とした分子標的遺伝子治療法開発2017

    • Author(s)
      降幡知巳、孫雨晨、原田まなみ、Hofbauer P Josefina, Gruber Christina、秋田英万、安西尚彦
    • Organizer
      日本がん分子標的治療学会 第1回シーズ・ニーズ(SN)ワークショップ
    • Data Source
      KAKENHI-PROJECT-17K19475
  • [Presentation] がん特異的遺伝子Cancer-type OATP1B3標的型RNA trans-splicing分子によるがん遺伝子治療の基盤構築2017

    • Author(s)
      森尾花恵、降幡知巳、孫雨晨、原田まなみ、秋田英万、Ulrich Koller、Anna Stierschneider、Josefina Pion Hofbauer、Christina Gruber、千葉寛、安西尚彦
    • Organizer
      第136回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-17K19475
  • [Presentation] 細胞内環境応答性脂質様材料を基盤としたマルチ創剤基盤2016

    • Author(s)
      秋田 英万
    • Organizer
      第31回 日本薬物動態学会
    • Place of Presentation
      松本 キッセイ文化ホール
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14934
  • [Presentation] 細胞内環境応答性脂質様材料: ssPalmが拓くマルチ創剤基盤2016

    • Author(s)
      秋田 英万
    • Organizer
      第1回 黒潮カンファレンス
    • Place of Presentation
      サンライズ九十九里
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] 細胞内環境応答性脂質様材料を 基盤としたマルチ創剤基盤2016

    • Author(s)
      秋田 英万
    • Organizer
      第31回 日本薬物動態学会
    • Place of Presentation
      松本 キッセイ文化ホール
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] 体内・細胞内動態の情報に基づくベクター開発と蛍光技術を用いたナノ粒子物性評価2016

    • Author(s)
      秋田 英万
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14934
  • [Presentation] Particle formed with ssPalm as a multi-nanoDDS platform2016

    • Author(s)
      Hidetaka Akita
    • Organizer
      3rd International Conference on Biomaterials Science in Tokyo (ICBS2016)
    • Place of Presentation
      東京大学本郷キャンパス
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14934
  • [Presentation] Particle formed by ssPalm as a multi-nanoDDS platform2016

    • Author(s)
      Hidetaka Akita
    • Organizer
      HIGOprogram in Kumamoto Univ
    • Place of Presentation
      熊本大学
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] 効率的な肝臓へのsiRNAデリバリーのための ビタミンE骨格、pH応答性並びにジスルフィド結合 開裂能を有する脂質様物質の分子チューニング2016

    • Author(s)
      秋田 英万
    • Organizer
      油脂優秀論文賞受賞講演会
    • Place of Presentation
      奈良女子大学
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] Particle formed by ssPalm as a nanoDDS platform for the genes and nucleic acids2016

    • Author(s)
      Hidetaka Akita
    • Organizer
      The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics
    • Place of Presentation
      Kyoto
    • Year and Date
      2016-06-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] Particle formed with ssPalm as a multi-nanoDDS platform2016

    • Author(s)
      Hidetaka Akita
    • Organizer
      3rd International Conference on Biomaterials Science in Tokyo (ICBS2016)
    • Place of Presentation
      東京大学本郷キャンパス
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] Functionalized Self-Nanoemulsion formed with SS-cleavable and pH-activated Lipid-like Material via Oil-to-Surfactant Transition2015

    • Author(s)
      Hiroki Tanaka, Syo Oasa, Masataka Kinjo, Kota Tange, Yuta Nakai, and Hideyoshi Harashima, Hidetaka Akita
    • Organizer
      第9回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      千葉大学(千葉県千葉市)
    • Year and Date
      2015-11-07
    • Data Source
      KAKENHI-PROJECT-15K14934
  • [Presentation] INVESTIGATION OF OPTIMAL NANOPARTICLE PROPERTIES ON DELIVERY TO THE INFLAMED COLON2015

    • Author(s)
      Ayaka Watanabe, Hiroki Tanaka, Tatsuya Ohkawara, Kota Tange, Hiroshi Takeda, Hideyoshi Harashima, Hidetaka Akita
    • Organizer
      第9回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      千葉大学(千葉県千葉市)
    • Year and Date
      2015-11-07
    • Data Source
      KAKENHI-PROJECT-15K14934
  • [Presentation] Keynote Lecture: Development of non-viral nanoDDS for DNA: Analysis, control of the intracellular trafficking and beyond…2015

    • Author(s)
      Hidetaka Akita
    • Organizer
      World Drug Delivery Summit 2015
    • Place of Presentation
      Houston (USA)
    • Year and Date
      2015-08-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] Development of a nanoDDS platform based on an analysis of intracellular trafficking2015

    • Author(s)
      秋田 英万
    • Organizer
      日本薬物動態学会 第30回年会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-11-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14934
  • [Presentation] ssPalmの分子チューニングに基づく肝臓標的型遺伝子・核酸デリバリー技術の開発2015

    • Author(s)
      秋田英万
    • Organizer
      日本DDS学会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] KALA修飾型脂質ナノ粒子を用いたナノワクチンプラットフォーム2015

    • Author(s)
      秋田英万、三浦尚也、シャヒーンモハメド、中村孝司、原島秀吉
    • Organizer
      遺伝子・デリバリー研究会 第15回シンポジウム
    • Place of Presentation
      京都薬科大学 (京都府京都市)
    • Year and Date
      2015-05-01
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] INVESTIGATION OF OPTIMAL NANOPARTICLE PROPERTIES ON DELIVERY TO THE INFLAMED COLON2015

    • Author(s)
      Ayaka Watanabe, Hiroki Tanaka, Tatsuya Ohkawara, Kota Tange, Hiroshi Takeda, Hideyoshi Harashima, Hidetaka Akita
    • Organizer
      第9回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      千葉大学(千葉県千葉市)
    • Year and Date
      2015-11-07
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] Particle formed by ssPalm as a nanoDDS platform for the genes and nucleic acids2015

    • Author(s)
      Hidetaka Akita
    • Organizer
      World Drug Delivery Summit 2015
    • Place of Presentation
      Houston (USA)
    • Year and Date
      2015-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] Development of a nanoDDS platform based on an analysis of intracellular trafficking2015

    • Author(s)
      Hidetaka Akita
    • Organizer
      日本薬物動態学会 第30回年会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-11-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] KALA修飾ナノ粒子の蛋白ワクチン技術としての応用2015

    • Author(s)
      秋田英万、三浦尚也、中村孝司、原島秀吉
    • Organizer
      日本薬剤学会 第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] pH応答性脂質様物質(ssPalm)を用いたナノ粒子構造体の物性評価2015

    • Author(s)
      田中浩揮、秋田英万、丹下耕太、中井悠太、原島秀吉
    • Organizer
      日本DDS学会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-02
    • Data Source
      KAKENHI-PROJECT-15H01806
  • [Presentation] KALA-modified multi-layered nano particles as antigen gene carrier for MHC Class-I mediated antigen presentation in DNA vaccine approach2011

    • Author(s)
      Shaheen SM, Akita H, Nakamura T, Takayama S, Futaki S, Yanashita A, Katoono R, Yui N, Harashima H
    • Organizer
      38th Annual Meeting & Exposition of the Controlled Release Society (CRS)
    • Place of Presentation
      Gaylord National Hotel and Convention Center (U.S.A.)
    • Year and Date
      2011-08-02
    • Data Source
      KAKENHI-PROJECT-22659006
  • [Presentation] 樹状細胞由来細胞を標的としたDNA遺伝子導入システム~DNAワクチンへの応用へ向けて~2011

    • Author(s)
      秋田英万
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都)(招待講演)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22659006
  • [Presentation] Dynamic analysis and control of intracellular trafficking of gene-encapsulating nano-carrier based on a real-time imaging2010

    • Author(s)
      秋田英万
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡(招待講演)
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-22689002
  • [Presentation] 遺伝子核酸医薬のin vivo適応型ナノキャリアーの実現に向けて2010

    • Author(s)
      秋田英万
    • Organizer
      第54回 日本薬学会関東支部大会
    • Place of Presentation
      東京薬科大学(招待講演)
    • Year and Date
      2010-10-02
    • Data Source
      KAKENHI-PROJECT-22689002
  • [Presentation] 多機能性エンベロープ型ナノ構造体を用いた遺伝子・核酸の細胞内動態制御へのアプローチ2010

    • Author(s)
      秋田英万
    • Organizer
      BMB2010
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22689002
  • [Presentation] Particle Tracking for Intracellular Trafficking of Octaarginine-Modified Liposome : Comparative Study with Adenovirus2010

    • Author(s)
      Akita H, Enoto K, Masuda T, Tani T, Mizuguchi H, Harashima H
    • Organizer
      The 13th Annual Meeting of the American Society of Gene and cell Therapy
    • Place of Presentation
      Wachington DC(USA)
    • Year and Date
      2010-05-23
    • Data Source
      KAKENHI-PROJECT-22689002
  • [Presentation] 体内動態制御と細胞内動態制御による低毒性ddsキャリア構築へのアプローチ2009

    • Author(s)
      秋田英万
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Presentation] 多機能性エンベロープ型ナノ構造体を用いた遺伝子の核輸送戦略2009

    • Author(s)
      秋田英万
    • Organizer
      第32回日本分子生物学会年会(ワークショップ)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Presentation] 多機能性エンベロープ型ナノ構造体を用いた細胞内動態制御:in vivo適応型ナノキャリアの実現に向けたアプローチ2009

    • Author(s)
      秋田英万
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京、後楽園ホテル
    • Data Source
      KAKENHI-PROJECT-20650072
  • [Presentation] 多機能性エンベロープ型ナノ構造体を用いた細胞内動態制御:in vivo適応型ナノキャリアの実現に向け2009

    • Author(s)
      秋田英万
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Presentation] Analysis of intracellular trafficking of pDNA and siRNA for a development of non-viral vector2009

    • Author(s)
      H. Akita, S. Hama, K. Kogure and H. Harashima
    • Organizer
      日本遺伝子治療学会
    • Place of Presentation
      札幌医科大学
    • Year and Date
      2009-06-12
    • Data Source
      KAKENHI-PROJECT-19021003
  • [Presentation] 多機能性エンベロープ型ナノ構造体を用いた遺伝子の核輸送戦略2009

    • Author(s)
      秋田英万
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜, パシフィコ横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Presentation] Novel approach for the nuclear delivery of DNA via step-wise membrane fusion2008

    • Author(s)
      H. Akita, A. Kudo, A. Minoura, K. Kog ure and H. Harashima
    • Organizer
      11th Liposome Research Days Conference
    • Place of Presentation
      横浜
    • Year and Date
      2008-07-20
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Presentation] 遺伝子デリバリーシステムの開発における細胞内動態の定量評価の意義:トランスレーショナルリサーチにおける新しい視点2007

    • Author(s)
      秋田英万
    • Organizer
      創剤フォーラム第13回若手研究会
    • Place of Presentation
      大阪
    • Year and Date
      2007-12-08
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Presentation] Cellular uptake mechanism and intracellular trafficking study of the novel C152-peptide-modified liposomes(C152-Lip)2007

    • Author(s)
      ディッキームダキュル、秋田英万、タンエルダル、原島秀吉
    • Organizer
      第23回日本DDS学会
    • Place of Presentation
      熊本(熊本日航ホテル)
    • Year and Date
      2007-06-15
    • Data Source
      KAKENHI-PROJECT-18200032
  • [Presentation] 細胞内動態解析に基づいた遺伝子キャリア開発へのアプローチ2007

    • Author(s)
      秋田英万.原島秀吉
    • Organizer
      生体機能シンポジウム若手フォーラム
    • Place of Presentation
      仙台(東北大学)
    • Year and Date
      2007-09-30
    • Data Source
      KAKENHI-PROJECT-19021003
  • [Presentation] 血管内皮標的化ペプチド搭載リポソームの細胞内取り込み機構の解析2007

    • Author(s)
      秋田英万、ディッキームダキュル、タンエルダル、原島秀吉
    • Organizer
      日本薬剤学会第22年会
    • Place of Presentation
      埼玉(大宮)大宮ソニックシティ
    • Year and Date
      2007-05-23
    • Data Source
      KAKENHI-PROJECT-19680025
  • [Presentation] 血管内皮細胞標的化ペプチド搭載リポソームの細胞内取り込み機構の解析2007

    • Author(s)
      秋田英万、ディッキー・ムダキュル、タン・エルダル、原島秀吉
    • Organizer
      日本薬剤学会第22年会
    • Place of Presentation
      大宮(大宮ソニックシティ)
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-18200032
  • 1.  HARASHIMA Hideyoshi (00183567)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 32 results
  • 2.  KAMIYA Hiroyuki (10204629)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 6 results
  • 3.  YAMADA Yuma (60451431)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 4.  小暮 健太朗 (70262540)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 7 results
  • 5.  BABA Yoshinobu (30183916)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  HYODO Mamoru (30548186)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KAJIMOTO Kazuaki (10416216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  HAYASHI Yasuhiro (30548178)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  Nishimura Masaharu (00208224)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Akita Shinsuke (00436403)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 11.  Furihata Tomomi (80401008)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 12.  中谷 明弘 (60301149)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  谷 知己 (80332378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  南川 典昭 (40209820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  畠山 浩人 (70504786)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 16.  中村 孝司 (20604458)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 17.  篠原 康雄 (60226157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  渡慶次 学 (60311437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  松尾 保孝 (90374652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  鈴木 雅 (10374290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  三川 信之 (40595196)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 22.  山口 匡 (40334172)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  KIMURA Hiroki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SANTIWARANGKOOL Sarochin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  Kaneda Atsushi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SATO Yusuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  OHKAWARA Tatsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  TAKEDA Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  居城 邦治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  新倉 謙一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  櫻井 遊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  喜多 知子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  山路 佳久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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