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Nakamura Takashi  中村 孝司

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NAKAMURA Takashi  中村 孝司

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Researcher Number 20604458
Other IDs
External Links
Affiliation (Current) 2021: 北海道大学, 薬学研究院, 助教
Affiliation (based on the past Project Information) *help 2016 – 2020: 北海道大学, 薬学研究院, 助教
2012 – 2016: 北海道大学, 薬学研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Physical pharmacy / Biomedical engineering/Biomaterial science and engineering / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Except Principal Investigator
Infectious disease medicine / Drug development chemistry / Medium-sized Section 90:Biomedical engineering and related fields
Keywords
Principal Investigator
がん免疫療法 / 薬物送達学 / ドラッグデリバリー / リポソーム / 脂質ナノ粒子 / ナノ粒子 / 膀胱がん / BCG / 免疫チェックポイント阻害剤 / がん免疫 … More / ワクチン / 癌免疫療法 / 脂質抗原 / デリバリーシステム / 癌免疫 / ヒト免疫学 / 網羅的遺伝子解析 / 網羅的遺伝子発現解析 / アジュバント / STING / 免疫チェックポイント阻害 / ドラッグデリバリーシステム / リンパ節 / siRNA / ナノテクノロジー / 制御性T細胞 / 腫瘍所属リンパ節 / 腫瘍関連微小環境 / NK細胞 … More
Except Principal Investigator
ミトコンドリア / 細胞内動態制御 / 結核 / ワクチン / 脂質 / ナノマシン / MEND / マイクロ流路 / 核内動態制御 / ナノパッケージング / pH-感受性カチオニック脂質 / 還元環境応答性 / ミトコンドリア送達 / ハイドロダイナミクス法 / 自己活性化システム / バイセル / パッケージング / 核送達 / KALA / 機能性核酸 / 脂質ワクチン / 感染症 / 細菌 / マクロファージ / 好中球 / 核酸ナノ医療 / ナノDDS / がん免疫療法 / ミトコンドリア遺伝子治療 / siRNA / 細胞内局在 / 脂質ナノ粒子 / 核酸送達 / 遺伝子治療 / ナノDDS Less
  • Research Projects

    (11 results)
  • Research Products

    (68 results)
  • Co-Researchers

    (20 People)
  •  PD-1抗体への獲得抵抗性を攻略する記憶NK細胞誘導型ナノがん免疫療法の開発Principal InvestigatorOngoing

    • Principal Investigator
      中村 孝司
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Hokkaido University
  •  Innovative gene/nucleic acid delivery system based on optimized intracellular trafficking stepsOngoing

    • Principal Investigator
      原島 秀吉
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Hokkaido University
  •  腫瘍微小環境のナノDDS関連免疫ステータス解析に基づいたナノがん免疫療法の開発Principal InvestigatorOngoing

    • Principal Investigator
      中村 孝司
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Hokkaido University
  •  Combined immunotherapy based on nano-DDS targeting tumor draining lymph nodesPrincipal Investigator

    • Principal Investigator
      Nakamura Takashi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Hokkaido University
  •  Combined cancer immunotherapy of PD-1 antibody and c-di-GMP loaded lipid nanoparticlesPrincipal Investigator

    • Principal Investigator
      NAKAMURA Takashi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Physical pharmacy
    • Research Institution
      Hokkaido University
  •  Lipid immunity in rhesus monkeys and development of a new anti-tuberculosis vaccine

    • Principal Investigator
      SUGITA Masahiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Kyoto University
  •  The effect of intracellular trafficking of BCG-CWS loaded nanoparticles on anti-bladder cancer activityPrincipal Investigator

    • Principal Investigator
      NAKAMURA Takashi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Hokkaido University
  •  Development of nano medicine for anti-bladder cancer based on human immunologyPrincipal Investigator

    • Principal Investigator
      NAKAMURA Takashi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      Hokkaido University
  •  Development of a new type of anti-tuberculosis vaccines by the use of lipid immunity

    • Principal Investigator
      SUGITA Masahiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Kyoto University
  •  Induction of antitumor immunity by nanoparticle incorporating alpha-galactocylceramidePrincipal Investigator

    • Principal Investigator
      NAKAMURA Takashi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Hokkaido University
  •  MENDで拓く遺伝子治療への道:遺伝子の運び屋からナノマシンへ

    • Principal Investigator
      HARASHIMA Hideyoshi
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hokkaido University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book Patent

  • [Book] ペプチド・タンパク性医薬品の新規DDS製剤の開発と応用-遺伝子医学MOOK別冊2011

    • Author(s)
      山田勇磨、中村孝司、原島秀吉
    • Total Pages
      8
    • Publisher
      メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Book] バイオテクノロジーシリーズ蛍光イメージング/MRIプローブの開発2011

    • Author(s)
      秋田英万、山田勇磨,中村孝司、畠山浩人、林泰弘、梶本和昭、原島秀吉
    • Total Pages
      10
    • Publisher
      CMC出版
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Journal Article] The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution2020

    • Author(s)
      Nakamura Takashi, Kawai Minori, Sato Yusuke, Maeki Masatoshi, Tokeshi Manabu, Harashima Hideyoshi
    • Journal Title

      Molecular Pharmaceutics

      Volume: 17 Pages: 944-953

    • DOI

      10.1021/acs.molpharmaceut.9b01182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03974, KAKENHI-PROJECT-18K19889
  • [Journal Article] The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy2019

    • Author(s)
      Endo Rikito, Nakamura Takashi, Kawakami Kyoko, Sato Yusuke, Harashima Hideyoshi
    • Journal Title

      Scientific Reports

      Volume: 9 Pages: 11335-11335

    • DOI

      10.1038/s41598-019-47799-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Journal Article] Innovative nanotechnologies for enhancing nucleic acids/gene therapy: Controlling intracellular trafficking to targeted biodistribution.2019

    • Author(s)
      Nakamura Takashi, Yamada Yuma, Sato Yusuke, Khalil A Ikramy, Harashima Hideyoshi
    • Journal Title

      Biomaterials.

      Volume: 218 Pages: 119329-119329

    • DOI

      10.1016/j.biomaterials.2019.119329

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19888, KAKENHI-PROJECT-19H01170, KAKENHI-PROJECT-17H02094, KAKENHI-PROJECT-17H03974, KAKENHI-PROJECT-17H05052, KAKENHI-PROJECT-18K19889
  • [Journal Article] Development of a Drug Delivery System for Cancer Immunotherapy2018

    • Author(s)
      Takashi Nakamura
    • Journal Title

      薬学雑誌

      Volume: 136 Issue: 11 Pages: 1477-1484

    • DOI

      10.1248/yakushi.16-00187

    • NAID

      130005267659

    • ISSN
      0031-6903, 1347-5231
    • Year and Date
      2018-08-31
    • Language
      Japanese
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-16K15102
  • [Journal Article] Reducing the Cytotoxicity of Lipid Nanoparticles Associated with a Fusogenic Cationic Lipid in a Natural Killer Cell Line by Introducing a Polycation-Based siRNA Core2018

    • Author(s)
      Nakamura Takashi、Yamada Koharu、Fujiwara Yuki、Sato Yusuke、Harashima Hideyoshi
    • Journal Title

      Molecular Pharmaceutics

      Volume: 15 Pages: 2142-2150

    • DOI

      10.1021/acs.molpharmaceut.7b01166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Journal Article] Modifying Cationic Liposomes with Cholesteryl-PEG Prevents Their Aggregation in Human Urine and Enhances Cellular Uptake by Bladder Cancer Cells2017

    • Author(s)
      Takashi Nakamura, Yosuke Noma, Yu Sakurai, Hideyoshi Harashima
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 40 Issue: 2 Pages: 234-237

    • DOI

      10.1248/bpb.b16-00770

    • NAID

      130005308415

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26713002
  • [Journal Article] Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics.2017

    • Author(s)
      Sato Y, Sakurai Y, Kajimoto K, Nakamura T, Yamada Y, Akita H, Harashima H.
    • Journal Title

      Macromolecular Biosciences

      Volume: 17 Pages: 1-16

    • DOI

      10.1002/mabi.201600179

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26282132, KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-26670741, KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-16K11180
  • [Journal Article] Integration of nano drug-delivery system with cancer immunotherapy2017

    • Author(s)
      Takashi Nakamura, Hideyoshi Harashima
    • Journal Title

      Therapeutic Delivery

      Volume: 8 Pages: 987-1000

    • DOI

      10.4155/tde-2017-0071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Journal Article] A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells2016

    • Author(s)
      Warashina S, Nakamura T, Sato Y, Fujiwara Y, Hyodo M, Hatakeyama H, Harashima H
    • Journal Title

      Journal of Controlled Release

      Volume: 225 Pages: 183-191

    • DOI

      10.1016/j.jconrel.2016.01.042

    • NAID

      120005981350

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26830101, KAKENHI-PROJECT-26713002
  • [Journal Article] Development of a multifunctional envelope-type nano device and its application to nanomedicine2016

    • Author(s)
      Sato Y, Nakamura T, Yamada Y, Harashima H.
    • Journal Title

      J Control Release.

      Volume: 244 Pages: 194-204

    • DOI

      10.1016/j.jconrel.2016.06.042

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-26670741, KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-16K11180
  • [Journal Article] Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines2016

    • Author(s)
      Takashi Nakamura, Moeka Kuroi, Yuki Fujiwara, Shota Warashina, Yusuke Sato, Hideyoshi Harashima
    • Journal Title

      Scientific Reports

      Volume: 6

    • DOI

      10.1038/srep37849

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26713002
  • [Journal Article] Influence of Endosomal Escape and Degradation of α-Galactosylceramide Loaded Liposomes on CD1d Antigen Presentation2015

    • Author(s)
      Takashi Nakamura, Moeka Kuroi, Hideyoshi Harashima
    • Journal Title

      Molecular Pharmaceutics

      Volume: 12 Pages: 2791-2799

    • DOI

      10.1021/mp500704e

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26560231
  • [Journal Article] Mechanism responsible for the antitumor effect of BCG-CWS using the LEEL method in a mouse bladder cancer model2014

    • Author(s)
      Takashi Nakamura, Masafumi Fukiage, Yoshiteru Suzuki, Ikuya Yano, Jun Miyazaki, Hiroyuki Nishiyama, Hideyuki Akaza, Hideyoshi Harashima
    • Journal Title

      Journal of Controlled Release

      Volume: 196 Pages: 161-167

    • DOI

      10.1016/j.jconrel.2014.10.007

    • NAID

      120005537473

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26560231, KAKENHI-PROJECT-26713002
  • [Journal Article] Glycerol monomycolate is a novel ligand for the human, but not mouse macrophage inducible C-type lectin, mincle2014

    • Author(s)
      Hattori Y, Morita, D, Fujiwara N, Mori D, Nakamura T, Harashima H, Yamasaki S, Sugita M.
    • Journal Title

      J Biol Chem.

      Volume: 289(22) Pages: 15405-12

    • DOI

      10.1074/jbc.m114.566489

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-12J04754, KAKENHI-PROJECT-14J03573, KAKENHI-PROJECT-24390255, KAKENHI-PROJECT-25460543, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-26670213, KAKENHI-PROJECT-26860323
  • [Journal Article] The nanoparticulation by octaarginine-modified liposome improvesα-galactosylceramide-mediated antitumor therapy via systemic administration2013

    • Author(s)
      Takashi Nakamura, Daiki Yamazaki, Jun Yamauchi, Hideyoshi Harashima
    • Journal Title

      J. Control. Release

      Volume: 171 Pages: 216-224

    • DOI

      10.1016/j.jconrel.2013.07.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Journal Article] Th1-skewed tissue responses to a mycolyl glycolipid in mycobacteria-infected rhesus macaques.2013

    • Author(s)
      Morita D, Miyamoto A, Hattori Y, Komori T, Nakamura T, lgarashi T, Harashima H, Sugita M
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 441(1) Pages: 108-113

    • DOI

      10.1016/j.bbrc.2013.10.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04754, KAKENHI-PROJECT-24390255
  • [Journal Article] A multifunctional envelope-type nano device for use in nanomedicine: concept and Applications.2012

    • Author(s)
      Nakamura T, Akita H, Yamada Y, Hatakeyama H, Harashima H
    • Journal Title

      Accounts of Chemical Research

      Volume: 45(7) Pages: 1113-1121

    • DOI

      10.1021/ar200254s

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001, KAKENHI-PUBLICLY-24107502
  • [Journal Article] KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine2011

    • Author(s)
      Shaheen SM, Akita H, Nakamura T, Takayama S, Futaki S, Yamashita A, Katoono R, Yui N, Harashima H
    • Journal Title

      Biomaterials

      Volume: 32(26) Pages: 6342-6350

    • DOI

      10.1016/j.biomaterials.2011.05.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001, KAKENHI-PROJECT-22659006
  • [Journal Article] Noninvasive and efficient transdermal delivery of CpGoligodeoxynucleotide for cancer immunotherapy2011

    • Author(s)
      Kigasawa K, Kajimoto K, Nakamura T, Hama S, Kanamura K, Harashima H, Kogure K
    • Journal Title

      J Control Release

      Volume: 150(3) Pages: 256-265

    • DOI

      10.1016/j.jconrel.2011.01.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Patent] 核内移行性を有する脂質膜構造体2011

    • Inventor(s)
      原島秀吉, 秋田英万、シャリフモハメドシャヒーン、中村孝司、石井聡一郎、二木史朗
    • Industrial Property Rights Holder
      原島秀吉,秋田英万、シャリフモハメドシャヒーン、中村孝司、石井聡一郎、二木史朗
    • Filing Date
      2011-04-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22229001
  • [Presentation] 脂質ナノ粒子のサイズと電荷がリンパ節移行とリンパ節内分布に与える影響2020

    • Author(s)
      中村孝司、河合美典、佐藤悠介、真栄城正寿、渡慶次学、原島秀吉
    • Organizer
      日本薬学会140年会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] STINGアゴニスト搭載脂質ナノ粒子によるメラノーマ肺転移の抗PD-1抗体抵抗性の改善2019

    • Author(s)
      佐藤孝紀、中村孝司、高橋直道、佐藤悠介、兵藤守、早川芳宏、原島秀吉
    • Organizer
      第23回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-18K19888
  • [Presentation] Improvement of PD-1 antibody resistance of melanoma lung metastasis by STING agonist loaded lipid nanoparticles2019

    • Author(s)
      Saro Takanori, Nakamura Takashi, Takahashi Nomichi, Sato Yusuke, Hyodo Mamoru, Hayakawa Yoshihiro, Harashima Hideyoshi
    • Organizer
      Liposome Research Days 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19888
  • [Presentation] Liposomal delivery of TLR3 agonist induces robust antitumor activity without systemic inflammation following intravenous administration.2019

    • Author(s)
      Haloho S, Nakamura T, Harashima H.
    • Organizer
      The 48th Annual Scientific Meeting of the Australian and New Zealand Society for Immunology (ASI) 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01170
  • [Presentation] TLR3 adjuvant-loaded liposome induce robust antitumor activity and reduces systemic inflammation following intravenous administration.2019

    • Author(s)
      Haloho S, Nakamura T, Harashima H
    • Organizer
      Liposome Research Days 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01170
  • [Presentation] ナノDDS技術を利用したがん免疫療法の開発2019

    • Author(s)
      中村孝司
    • Organizer
      第35回 日本DDS学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] がん免疫療法のための核酸医薬DDS技術2019

    • Author(s)
      中村孝司
    • Organizer
      日本薬剤学会 第34年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] STINGアゴニスト搭載脂質ナノ粒子の併用によるメラノーマ肺転移の抗PD-1抗体抵抗性の改善2019

    • Author(s)
      佐藤孝紀、中村孝司、高橋直道、佐藤悠介、兵藤守、早川芳宏、原島秀吉
    • Organizer
      日本薬学会北海道支部第146回例会
    • Data Source
      KAKENHI-PROJECT-18K19888
  • [Presentation] STINGアゴニスト搭載脂質ナノ粒子を用いた抗PD-1抗体抵抗性メラノーマ肺転移に対するがん免疫療法2019

    • Author(s)
      中村孝司、佐藤孝紀、高橋直道、佐藤悠介、兵藤守、早川芳宏、原島秀吉
    • Organizer
      第35回 日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19888
  • [Presentation] ナノDDSを基盤としたがん免疫療法開発における腫瘍微小環境の免疫状態解析の有用性検証2019

    • Author(s)
      1.川上今日子、中村孝司、佐藤悠介、兵藤守、畠山浩人、早川芳宏、原島秀吉
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K19888
  • [Presentation] ナノDDS技術を利用したがん免疫療法の開発2019

    • Author(s)
      中村孝司
    • Organizer
      第35回 日本DDS学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19888
  • [Presentation] siRNA搭載脂質ナノ粒子を用いた樹状細胞のIDO1発現制御と免疫細胞療法への展開2019

    • Author(s)
      遠藤力斗、中村孝司、川上今日子、佐藤悠介、原島秀吉
    • Organizer
      日本薬剤学会 第34年会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] ナノDDSを基盤としたがん免疫療法における腫瘍内免疫状態解析の有用性検証2019

    • Author(s)
      川上今日子、中村孝司、佐藤悠介、兵藤守、畠山浩人、早川芳宏、原島秀吉
    • Organizer
      日本薬学会北海道支部第146回例会
    • Data Source
      KAKENHI-PROJECT-18K19888
  • [Presentation] ポリカチオンを用いたsiRNA搭載脂質ナノ粒子によるヒトNK細胞株への毒性の軽減2018

    • Author(s)
      山田小春、中村孝司、藤原優希、佐藤悠介、原島秀吉
    • Organizer
      日本薬学会北海道支部第145回例会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] 脂質ナノ粒子を基盤としたがん免疫療法のためのナノDDS開発2018

    • Author(s)
      中村孝司
    • Organizer
      日本薬学会第138年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15102
  • [Presentation] 脂質ナノ粒子を基盤としたがん免疫療法のためのナノDDS開発2018

    • Author(s)
      中村孝司
    • Organizer
      日本薬学会第138年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] 微小化脂質ナノ粒子によるアジュバントのリンパ節送達2018

    • Author(s)
      中村孝司、河合美典、佐藤悠介、真栄城正寿、渡慶次学、原島秀吉
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] 脂質ナノ粒子を用いたヒトNK細胞株NK-92へのsiRNA導入2018

    • Author(s)
      中村孝司、山田小春、藤原優希、佐藤悠介、原島秀吉
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] ヒトナチュラルキラー細胞株への毒性回避を目指したsiRNA搭載脂質ナノ粒子の開発2018

    • Author(s)
      山田小春、中村孝司、藤原優希、佐藤悠介、原島秀吉
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] siRNA搭載脂質ナノ粒子を用いた免疫細胞の遺伝子発現制御2018

    • Author(s)
      中村孝司、黒井萌花、山田小春、藤原優希、藁科翔太、佐藤悠介、原島秀吉
    • Organizer
      第22回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] siRNA搭載脂質ナノ粒子を用いた樹状細胞のIDO発現抑制2018

    • Author(s)
      遠藤力斗、中村孝司、佐藤悠介、原島秀吉
    • Organizer
      日本薬学会北海道支部第145回例会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] Cancer immunotherapy by STING ligand loaded lipid nanoparticles2017

    • Author(s)
      Naomichi Takahashi, Takashi Nakamura, Yusuke Sato, Mamoru Hyodo, Yoshihiro Hayakawa, Hideyoshi Harashima
    • Organizer
      The 36th Sapporo International Cancer Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15102
  • [Presentation] 脂質ナノ粒子によるSTING経路活性化を介したがん免疫療法2017

    • Author(s)
      高橋直道、中村孝司、佐藤悠介、兵藤守、早川芳宏、原島秀吉
    • Organizer
      第33会日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K15102
  • [Presentation] STINGリガンド搭載ナノDDSを基盤としたがん免疫療法2017

    • Author(s)
      中村孝司、高橋直道、宮部寛子、佐藤悠介、兵藤守、早川芳宏、原島秀吉
    • Organizer
      第21回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-16K15102
  • [Presentation] リンパ節内樹状細胞を標的とした極小ナノキャリアシステムの開発2017

    • Author(s)
      河合美典、中村孝司、佐藤悠介、真栄城正寿、渡慶次学、原島秀吉
    • Organizer
      第33会日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03974
  • [Presentation] STINGリガンド搭載脂質ナノ粒子を用いたがん免疫療法2017

    • Author(s)
      高橋直道、中村孝司、佐藤悠介、兵藤守、早川芳宏、原島秀吉
    • Organizer
      日本薬学会北海道支部第144回例会
    • Data Source
      KAKENHI-PROJECT-16K15102
  • [Presentation] 脂質ナノ粒子を用いたヒト免疫細胞株への効率的siRNA導入2016

    • Author(s)
      中村孝司、黒井萌花、藤原優希、藁科翔太、佐藤悠介、原島秀吉
    • Organizer
      第32回日本DDS学会学術集会
    • Place of Presentation
      グランシップ(静岡県・静岡市)
    • Year and Date
      2016-06-30
    • Data Source
      KAKENHI-PROJECT-26713002
  • [Presentation] ナノテクノロジーで制御するがんアジュバントシステムの創製2016

    • Author(s)
      中村孝司
    • Organizer
      日本薬剤学会第31年会
    • Place of Presentation
      長良川国際会議場・岐阜都ホテル(岐阜県・岐阜市)
    • Year and Date
      2016-05-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15102
  • [Presentation] ナノテクノロジーで制御するがんアジュバントシステムの創製2016

    • Author(s)
      中村孝司
    • Organizer
      日本薬剤学会第31年会
    • Place of Presentation
      長良川国際会議場・岐阜都ホテル(岐阜県・岐阜市)
    • Year and Date
      2016-05-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-26713002
  • [Presentation] STING ligand loaded lipid nanoparticles enhance cancer immunotherapy2016

    • Author(s)
      Takashi Nakamura, Hiroko Miyabe, Mamoru Hyodo, Yusuke Sato, Yoshihiro Hayakawa, Hideyoshi Harashima
    • Organizer
      3rd International Conference on Biomaterials Science
    • Place of Presentation
      東京大学伊藤国際学術センター(東京都・文京区)
    • Year and Date
      2016-11-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15102
  • [Presentation] がん免疫療法を促進するDrug Delivery Systemの開発2015

    • Author(s)
      中村孝司
    • Organizer
      日本薬学会北海道支部第142回例会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2015-05-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-26713002
  • [Presentation] がん免疫療法を促進するDrug Delivery Systemの開発2015

    • Author(s)
      中村孝司
    • Organizer
      日本薬学会北海道支部第142回例会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2015-05-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-26560231
  • [Presentation] 樹状細胞への効率的siRNAデリバリーシステムの開発2015

    • Author(s)
      中村孝司、藁科翔太、佐藤悠介、兵藤守、畠山浩人、原島秀吉
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎ブリックホール・長崎新聞文化ホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26713002
  • [Presentation] BCG-CWS搭載ナノ粒子の抗膀胱がん作用機序2014

    • Author(s)
      中村孝司、吹上雅文、鈴木嘉晃、矢野郁也、宮崎淳、西山博之、赤座英之、原島秀吉
    • Organizer
      第7回BCG注入療法研究会
    • Place of Presentation
      東京 如水会館
    • Year and Date
      2014-11-21
    • Data Source
      KAKENHI-PROJECT-26560231
  • [Presentation] オクタアルギニン修飾ナノ粒子によるNKT細胞を介した癌免疫療法の増強2014

    • Author(s)
      中村孝司、山崎大樹、山内順、原島秀吉
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] オクタアルギニン修飾ナノ粒子によるNKT細胞を介した癌免疫療法の増強2014

    • Author(s)
      中村孝司、山崎大樹、山内順、原島秀吉
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本 熊本大学
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] オクタアルギニン修飾ナノ粒子によるNKT細胞を介した抗腫瘍免疫の促進2013

    • Author(s)
      中村孝司、山崎大樹、山内順、原島秀吉
    • Organizer
      日本薬剤学会 第28年会
    • Place of Presentation
      名古屋 ウインクあいち
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] The nanoparticulation ofα-galactosylceramide by octaarginine-modified liposome enhancesα-galactosylceramide mediated antitumor effects in an experimental lung metastasis model2013

    • Author(s)
      Nakamura T, Yamazaki D, Yamauchi J, Harashima H
    • Organizer
      40^<th> Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] オクタアルギニン修飾ナノ粒子によるNKT細胞を介した抗腫瘍免疫の促進2013

    • Author(s)
      中村孝司、山崎大樹、山内順、原島秀吉
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] Delivery system for cancer immunotherapy2013

    • Author(s)
      Nakamura T
    • Organizer
      The 16th SNU-HU JOINT SYMPOSIUM
    • Place of Presentation
      Seoul National University, Soul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] The nanoparticulation of α-galactosylceramide by octaarginine-modified liposome enhances α-galactosylceramide mediated antitumor effects in an experimental lung metastasis model2013

    • Author(s)
      Nakamura T, Yamazaki D, Yamauchi J, Harashima H
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] α-Galactosylceramide incorporated octaarginine-modified nanoparticles inhibit experimental tumor metastasis2012

    • Author(s)
      Yamazaki D, Nakamura T, Harashima H
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] α-Galactosylceramide incorporated octaarginine-modified nanoparticles inhibit experimental tumor metastasis2012

    • Author(s)
      Yamazaki Daiki, Nakamura Takashi, Harashima Hideyoshi
    • Organizer
      第41回 日本免疫学会総会
    • Place of Presentation
      神戸国際会議場、神戸国際展示場、神戸ポートピアホテル(兵庫県)
    • Data Source
      KAKENHI-PROJECT-24790037
  • [Presentation] BCG-CWS搭載ナノ粒子を用いた膀胱がん免疫療法剤の開発

    • Author(s)
      中村孝司、吹上雅文、鈴木嘉晃、矢野郁也、宮崎淳、西山博之、赤座英之、中山俊憲、原島秀吉
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸 神戸学院大学 兵庫医療大学
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26713002
  • [Presentation] 免疫応答の増強を可能とするエンドソーム脱出促進型siRNAナノキャリアの開発

    • Author(s)
      藁科翔太、中村孝司、佐藤悠介、兵藤守、畠山浩人、原島秀吉
    • Organizer
      第36回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      徳島 徳島大学
    • Year and Date
      2014-11-20 – 2014-11-21
    • Data Source
      KAKENHI-PROJECT-26713002
  • [Presentation] BCG-CWS搭載ナノ粒子を用いた膀胱がん免疫療法剤の開発

    • Author(s)
      中村孝司、吹上雅文、鈴木嘉晃、矢野郁也、宮崎淳、西山博之、赤座英之、中山俊憲、原島秀吉
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸 神戸学院大学 兵庫医療大学
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-26560231
  • 1.  HARASHIMA Hideyoshi (00183567)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 2.  SUGITA Masahiko (80333532)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  山田 勇磨 (60451431)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 4.  IGARASHI Tatuhiko (90467431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  兵藤 守 (30548186)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  馬場 嘉信 (30183916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  篠原 康雄 (60226157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  小暮 健太朗 (70262540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  紙谷 浩之 (10204629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  渡慶次 学 (60311437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  松尾 保孝 (90374652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  秋田 英万 (80344472)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  佐藤 悠介 (10735624)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 14.  KAJIMOTO Kazuyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  櫻井 遊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  喜多 知子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  藤原 永年
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  山崎 晶
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  森田 大輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  畠山 浩人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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