Nakamura Takashi 中村孝司

… Alternative Names

NAKAMURA Takashi 中村孝司

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Researcher Number	20604458
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, 薬学系, 教授
Affiliation (based on the past Project Information) *help	2025: 金沢大学, 薬学系, 教授 2023 – 2025: 北海道大学, 薬学研究院, 准教授 2016 – 2022: 北海道大学, 薬学研究院, 助教 2012 – 2016: 北海道大学, 薬学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Physical pharmacy / Medium-sized Section 90:Biomedical engineering and related fields / Medium-sized Section 50:Oncology and related fields / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Infectious disease medicine / Basic Section 56030:Urology-related / Basic Section 42020:Veterinary medical science-related / Broad Section D / Medium-sized Section 90:Biomedical engineering and related fields / Drug development chemistry
Keywords	Principal Investigator 薬物送達学 / がん免疫療法 / ナノ粒子 / 脂質ナノ粒子 / リポソーム / ドラッグデリバリー / NK細胞 / がん免疫 / 免疫チェックポイント阻害剤 / アジュバント … More / BCG / 膀胱がん / デリバリーシステム / ナノDDS / 腫瘍血管破壊 / 腫瘍血管内皮 / がん治療 / メモリー細胞 / 腫瘍関連微小環境 / 腫瘍所属リンパ節 / 制御性T細胞 / ナノテクノロジー / siRNA / リンパ節 / ドラッグデリバリーシステム / 免疫チェックポイント阻害 / STING / 網羅的遺伝子発現解析 / 網羅的遺伝子解析 / ヒト免疫学 / 癌免疫 / 脂質抗原 / 癌免疫療法 / ワクチン … More Except Principal Investigator ミトコンドリア / LNP / ナノ医療 / DDS / 脂質 / ワクチン / 結核 / 細胞内動態制御 / 癌幹細胞 / 腫瘍溶解性ウイルス / 筋層浸潤性膀胱癌 / 遺伝子改変マウス / 糖脂質 / T細胞 / スフィンゴ脂質 / IBD / 腫瘍血管 / mRNA / スマートポリマー / ナノＤＤＳ / 核酸送達 / 脂質ナノ粒子 / 細胞内局在 / siRNA / ミトコンドリア遺伝子治療 / がん免疫療法 / ナノDDS / 核酸ナノ医療 / ナノ医薬品 / ゲノム編集 / がん免疫 / 律速段階 / 遺伝子治療 / 核酸医薬 / 好中球 / マクロファージ / 細菌 / 感染症 / 脂質ワクチン / 機能性核酸 / KALA / 核送達 / パッケージング / バイセル / 自己活性化システム / ハイドロダイナミクス法 / ミトコンドリア送達 / 還元環境応答性 / pH-感受性カチオニック脂質 / ナノパッケージング / 核内動態制御 / マイクロ流路 / MEND / ナノマシン Less

Development of a novel oncolytic viral therapy targeting cancer stem cell for muscle-invasive bladder cancer
- Principal Investigator
  
  白川利朗
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kobe University
メモリー様NK細胞を駆動する新たなナノがん免疫療法の開拓Principal Investigator
- Principal Investigator
  
  中村孝司
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
ナノDDSによる生体内機能強化NK細胞の創出と新規がん免疫療法基盤の構築Principal Investigator
- Principal Investigator
  
  中村孝司
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kanazawa University
  Hokkaido University
Activated mRNA delivery system based on core-shell structured LNP with smart polymers
- Principal Investigator
  
  原島秀吉
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section D
- Research Institution
  Hokkaido University
炎症性腸疾患におけるスフィンゴ糖脂質による治療を目指した基礎的研究
- Principal Investigator
  
  山下匡
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Azabu University
ナノDDSで挑む腫瘍血管内皮細胞を標的とした新機軸のがん治療法の開発Principal Investigator
- Principal Investigator
  
  中村孝司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Hokkaido University
Nano cancer immunotherapy using memory NK cells against PD-1 blockade resistant tumorPrincipal Investigator
- Principal Investigator
  
  Nakamura Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Hokkaido University
Innovative gene/nucleic acid delivery system based on optimized intracellular trafficking steps
- Principal Investigator
  
  HARASHIMA HIDEYOSHI
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
Development of nano cancer immunotherapy based on immune status in tumorPrincipal Investigator
- Principal Investigator
  
  Nakamura Takashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
Combined immunotherapy based on nano-DDS targeting tumor draining lymph nodesPrincipal Investigator
- Principal Investigator
  
  Nakamura Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hokkaido University
Combined cancer immunotherapy of PD-1 antibody and c-di-GMP loaded lipid nanoparticlesPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Hokkaido University
Lipid immunity in rhesus monkeys and development of a new anti-tuberculosis vaccine
- Principal Investigator
  
  SUGITA Masahiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kyoto University
The effect of intracellular trafficking of BCG-CWS loaded nanoparticles on anti-bladder cancer activityPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Hokkaido University
Development of nano medicine for anti-bladder cancer based on human immunologyPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hokkaido University
Development of a new type of anti-tuberculosis vaccines by the use of lipid immunity
- Principal Investigator
  
  SUGITA Masahiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kyoto University
Induction of antitumor immunity by nanoparticle incorporating alpha-galactocylceramidePrincipal Investigator
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hokkaido University
MENDで拓く遺伝子治療への道：遺伝子の運び屋からナノマシンへ
- Principal Investigator
  
  HARASHIMA Hideyoshi
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hokkaido University

[Book] 新規モダリティ医薬品のための新しいＤＤＳ技術と製剤化2023
- Author(s)
  中村孝司、原島秀吉
- Total Pages
  580
- Publisher
  技術情報協会
- ISBN
  9784861049361
- Data Source
  KAKENHI-PROJECT-19H01170
[Book] 創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術2021
- Author(s)
  中村孝司（他執筆者:101名、企画編集: 技術情報協会）
- Total Pages
  598
- Publisher
  技術情報協会
- ISBN
  9784861048562
- Data Source
  KAKENHI-PROJECT-20H03373
[Book] ペプチド・タンパク性医薬品の新規DDS製剤の開発と応用-遺伝子医学MOOK別冊2011
- Author(s)
  山田勇磨、中村孝司、原島秀吉
- Total Pages
  8
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-22229001
[Book] バイオテクノロジーシリーズ蛍光イメージング/MRIプローブの開発2011
- Author(s)
  秋田英万、山田勇磨,中村孝司、畠山浩人、林泰弘、梶本和昭、原島秀吉
- Total Pages
  10
- Publisher
  CMC出版
- Data Source
  KAKENHI-PROJECT-22229001
[Journal Article] Harnessing Topology and Stereochemistry of Glycidylamine‐Derived Lipid Nanoparticles for in Vivo mRNA Delivery to Immune Cells in Spleen and Their Application for Cancer Vaccination2023
- Author(s)
  Abd Elwakil Mahmoud M.、Suzuki Ryota、Khalifa Alaa M.、Elshami Rania M.、Isono Takuya、Elewa Yaser H.A.、Sato Yusuke、Nakamura Takashi、Satoh Toshifumi、Harashima Hideyoshi
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 33 Issue: 45 Pages: 1-12
- DOI
  10.1002/adfm.202303795
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ0024, KAKENHI-PROJECT-22K19907, KAKENHI-PROJECT-23H05451
[Journal Article] Innovative cancer nanomedicine based on immunology, gene editing, intracellular trafficking control2022
- Author(s)
  Yamada Yuma、Sato Yusuke、Nakamura Takashi、Harashima Hideyoshi
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 348 Pages: 357-369
- DOI
  10.1016/j.jconrel.2022.05.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03373, KAKENHI-PROJECT-20H04523
[Journal Article] Intravenous liposomal vaccine enhances CTL generation, but not until antigen presentation2022
- Author(s)
  Nakamura Takashi、Haloho Sion Elisabeth Elfainatur、Harashima Hideyoshi
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 343 Pages: 1-12
- DOI
  10.1016/j.jconrel.2022.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01170
[Journal Article] Interval- and cycle-dependent combined effect of STING agonist loaded lipid nanoparticles and a PD-1 antibody2022
- Author(s)
  Khalifa Alaa M.、Nakamura Takashi、Sato Yusuke、Sato Takanori、Hyodo Mamoru、Hayakawa Yoshihiro、Harashima Hideyoshi
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 624 Pages: 122034-122034
- DOI
  10.1016/j.ijpharm.2022.122034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03373
[Journal Article] Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines2022
- Author(s)
  Nakamura Takashi、Sato Yusuke、Yamada Yuma、Abd Elwakil Mahmoud M.、Kimura Seigo、Younis Mahmoud A.、Harashima Hideyoshi
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: 188 Pages: 114417-114417
- DOI
  10.1016/j.addr.2022.114417
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03373, KAKENHI-PROJECT-20H04523, KAKENHI-PROJECT-21F21105, KAKENHI-PROJECT-21J10047
[Journal Article] Combined nano cancer immunotherapy based on immune status in a tumor microenvironment2022
- Author(s)
  Nakamura Takashi、Kawakami Kyoko、Nomura Momoka、Sato Yusuke、Hyodo Mamoru、Hatakeyama Hiroto、Hayakawa Yoshihiro、Harashima Hideyoshi
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 345 Pages: 200-213
- DOI
  10.1016/j.jconrel.2022.03.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03387, KAKENHI-PROJECT-19H01170
[Journal Article] The nanomedicine rush: New strategies for unmet medical needs based on innovative nano DDS2021
- Author(s)
  Sato Yusuke、Nakamura Takashi、Yamada Yuma、Harashima Hideyoshi
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 330 Pages: 305-316
- DOI
  10.1016/j.jconrel.2020.12.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03373, KAKENHI-PROJECT-18K19888
[Journal Article] The hydrophobic tail of a pH-sensitive cationic lipid influences siRNA transfection activity and toxicity in human NK cell lines.2021
- Author(s)
  Nakamura T, Nakade T, Yamada K, Sato Y, Harashima H
- Journal Title
  
  Int J Pharm
  
  Volume: 609 Pages: 121140-121140
- DOI
  10.1016/j.ijpharm.2021.121140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01170, KAKENHI-PROJECT-20H03373
[Journal Article] STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation.2021
- Author(s)
  Nakamura T, Sato T, Endo R, Sasaki S, Takahashi N, Sato Y, Hyodo M, Hayakawa Y, Harashima H.
- Journal Title
  
  J Immunotherapy Cancer
  
  Volume: 9 Issue: 7 Pages: e002852-e002852
- DOI
  10.1136/jitc-2021-002852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01170, KAKENHI-PROJECT-20H03373
[Journal Article] Evolution of drug delivery system from viewpoint of controlled intracellular trafficking and selective tissue targeting toward future nanomedicine2020
- Author(s)
  Yamada Yuma、Sato Yusuke、Nakamura Takashi、Harashima Hideyoshi
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 327 Pages: 533-545
- DOI
  10.1016/j.jconrel.2020.09.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19888
[Journal Article] Lipid nanoparticles fuse with cell membranes of immune cells at low temperatures leading to the loss of transfection activity2020
- Author(s)
  Nakamura T, Yamada K, Sato Y, Harashima H.
- Journal Title
  
  Int J Pharm.
  
  Volume: 587 Pages: 119652-119652
- DOI
  10.1016/j.ijpharm.2020.119652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01170
[Journal Article] The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution2020
- Author(s)
  Nakamura Takashi, Kawai Minori, Sato Yusuke, Maeki Masatoshi, Tokeshi Manabu, Harashima Hideyoshi
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 17 Issue: 3 Pages: 944-953
- DOI
  10.1021/acs.molpharmaceut.9b01182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03974, KAKENHI-PROJECT-18K19889, KAKENHI-PROJECT-19H01170
[Journal Article] The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy2019
- Author(s)
  Endo Rikito, Nakamura Takashi, Kawakami Kyoko, Sato Yusuke, Harashima Hideyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 11335-11335
- DOI
  10.1038/s41598-019-47799-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03974
[Journal Article] Innovative nanotechnologies for enhancing nucleic acids/gene therapy: Controlling intracellular trafficking to targeted biodistribution2019
- Author(s)
  Nakamura Takashi, Yamada Yuma, Sato Yusuke, Khalil A Ikramy, Harashima Hideyoshi
- Journal Title
  
  Biomaterials
  
  Volume: 218 Pages: 119329-119329
- DOI
  10.1016/j.biomaterials.2019.119329
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19888, KAKENHI-PROJECT-19H01170, KAKENHI-PROJECT-17H02094, KAKENHI-PROJECT-17H03974, KAKENHI-PROJECT-17H05052, KAKENHI-PROJECT-18K19889
[Journal Article] Reducing the Cytotoxicity of Lipid Nanoparticles Associated with a Fusogenic Cationic Lipid in a Natural Killer Cell Line by Introducing a Polycation-Based siRNA Core2018
- Author(s)
  Nakamura Takashi、Yamada Koharu、Fujiwara Yuki、Sato Yusuke、Harashima Hideyoshi
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 15 Issue: 6 Pages: 2142-2150
- DOI
  10.1021/acs.molpharmaceut.7b01166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03974
[Journal Article] Innovative technologies in Nanomedicines: from passive targeting to active targeting/from controlled pharmacokinetics to controlled intracellular pharmacokinetics.2017
- Author(s)
  Sato Y, Sakurai Y, Kajimoto K, Nakamura T, Yamada Y, Akita H, Harashima H.
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 17 Issue: 1 Pages: 1-16
- DOI
  10.1002/mabi.201600179
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26282132, KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-26670741, KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-16K11180
[Journal Article] Integration of nano drug-delivery system with cancer immunotherapy2017
- Author(s)
  Takashi Nakamura, Hideyoshi Harashima
- Journal Title
  
  Therapeutic Delivery
  
  Volume: 8 Issue: 11 Pages: 987-1000
- DOI
  10.4155/tde-2017-0071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03974
[Journal Article] Modifying Cationic Liposomes with Cholesteryl-PEG Prevents Their Aggregation in Human Urine and Enhances Cellular Uptake by Bladder Cancer Cells2017
- Author(s)
  Takashi Nakamura, Yosuke Noma, Yu Sakurai, Hideyoshi Harashima
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 2 Pages: 234-237
- DOI
  10.1248/bpb.b16-00770
- NAID
  130005308415
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26713002
[Journal Article] A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells.2016
- Author(s)
  Warashina S, Nakamura T, Sato Y, Fujiwara Y, Hyodo M, Hatakeyama H, Harashima H
- Journal Title
  
  J Control Release.
  
  Volume: 225 Pages: 183-191
- DOI
  10.1016/j.jconrel.2016.01.042
- NAID
  120005981350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26830101, KAKENHI-PROJECT-26713002
[Journal Article] Development of a multifunctional envelope-type nano device and its application to nanomedicine.2016
- Author(s)
  Sato Y, Nakamura T, Yamada Y, Harashima H.
- Journal Title
  
  J Control Release
  
  Volume: 244 Pages: 194-204
- DOI
  10.1016/j.jconrel.2016.06.042
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-26670741, KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-16K11180
[Journal Article] Development of a Drug Delivery System for Cancer Immunotherapy2016
- Author(s)
  Takashi Nakamura
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 136 Issue: 11 Pages: 1477-1484
- DOI
  10.1248/yakushi.16-00187
- NAID
  130005267659
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2016-11-01
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-16K15102
[Journal Article] Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines2016
- Author(s)
  Takashi Nakamura, Moeka Kuroi, Yuki Fujiwara, Shota Warashina, Yusuke Sato, Hideyoshi Harashima
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1
- DOI
  10.1038/srep37849
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26713002
[Journal Article] Influence of Endosomal Escape and Degradation of α-Galactosylceramide Loaded Liposomes on CD1d Antigen Presentation2015
- Author(s)
  Takashi Nakamura, Moeka Kuroi, Hideyoshi Harashima
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 12 Issue: 8 Pages: 2791-2799
- DOI
  10.1021/mp500704e
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26560231
[Journal Article] Mechanism responsible for the antitumor effect of BCG-CWS using the LEEL method in a mouse bladder cancer model2014
- Author(s)
  Takashi Nakamura, Masafumi Fukiage, Yoshiteru Suzuki, Ikuya Yano, Jun Miyazaki, Hiroyuki Nishiyama, Hideyuki Akaza, Hideyoshi Harashima
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 196 Pages: 161-167
- DOI
  10.1016/j.jconrel.2014.10.007
- NAID
  120005537473
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26560231, KAKENHI-PROJECT-26713002
[Journal Article] Glycerol monomycolate is a novel ligand for the human, but not mouse macrophage inducible C-type lectin, Mincle.2014
- Author(s)
  Hattori Y, Morita, D, Fujiwara N, Mori D, Nakamura T, Harashima H, Yamasaki S, Sugita M.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289(22) Issue: 22 Pages: 15405-12
- DOI
  10.1074/jbc.m114.566489
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12J04754, KAKENHI-PROJECT-14J03573, KAKENHI-PROJECT-24390255, KAKENHI-PROJECT-25460543, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-26670213, KAKENHI-PROJECT-26860323
[Journal Article] Th1-skewed tissue responses to a mycolyl glycolipid in mycobacteria-infected rhesus macaques.2013
- Author(s)
  Morita D, Miyamoto A, Hattori Y, Komori T, Nakamura T, lgarashi T, Harashima H, Sugita M
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 441(1) Issue: 1 Pages: 108-113
- DOI
  10.1016/j.bbrc.2013.10.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04754, KAKENHI-PROJECT-24390255
[Journal Article] The nanoparticulation by octaarginine-modified liposome improves α-galactosylceramide-mediated antitumor therapy via systemic administration2013
- Author(s)
  Takashi Nakamura, Daiki Yamazaki, Jun Yamauchi, Hideyoshi Harashima
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 171 Issue: 2 Pages: 216-224
- DOI
  10.1016/j.jconrel.2013.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790037
[Journal Article] A Multifunctional Envelope-type Nanodevice for Use in Nanomedicine: Concept and Applications2012
- Author(s)
  Nakamura T, Akita H, Yamada Y, Hatakeyama H, Harashima H
- Journal Title
  
  Acc Chem Res
  
  Volume: 45(7) Issue: 7 Pages: 1113-1121
- DOI
  10.1021/ar200254s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229001, KAKENHI-PUBLICLY-24107502
[Journal Article] Noninvasive and efficient transdermal delivery of CpGoligodeoxynucleotide for cancer immunotherapy2011
- Author(s)
  Kigasawa K, Kajimoto K, Nakamura T, Hama S, Kanamura K, Harashima H, Kogure K
- Journal Title
  
  J Control Release
  
  Volume: 150(3) Issue: 3 Pages: 256-265
- DOI
  10.1016/j.jconrel.2011.01.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229001
[Journal Article] KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine2011
- Author(s)
  Shaheen SM, Akita H, Nakamura T, Takayama S, Futaki S, Yamashita A, Katoono R, Yui N, Harashima H
- Journal Title
  
  Biomaterials
  
  Volume: 32(26) Issue: 26 Pages: 6342-6350
- DOI
  10.1016/j.biomaterials.2011.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229001, KAKENHI-PROJECT-22659006
[Patent] 脂質ナノ粒子2022
- Inventor(s)
  中村孝司、原島秀吉、佐藤悠介、山田小春、中出泰誠
- Industrial Property Rights Holder
  中村孝司、原島秀吉、佐藤悠介、山田小春、中出泰誠
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20H03373
[Patent] 脂質ナノ粒子2021
- Inventor(s)
  中村孝司、原島秀吉、佐藤悠介、山田小春、中出泰誠
- Industrial Property Rights Holder
  国立大学法人北海道大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-023184
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19H01170
[Patent] 核内移行性を有する脂質膜構造体2011
- Inventor(s)
  原島秀吉, 秋田英万、シャリフモハメドシャヒーン、中村孝司、石井聡一郎、二木史朗
- Industrial Property Rights Holder
  原島秀吉,秋田英万、シャリフモハメドシャヒーン、中村孝司、石井聡一郎、二木史朗
- Filing Date
  2011-04-20
- Overseas
- Data Source
  KAKENHI-PROJECT-22229001
[Presentation] 腫瘍血管内皮細胞の機能制御と自然免疫活性化を起点とした新規がん治療法の開発2023
- Author(s)
  上田智貴、中村孝司、遠藤力斗、佐藤悠介、原島秀吉
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] ナノDDSを基盤とした腫瘍血管破壊を誘導する新規がん治療法の開発2023
- Author(s)
  遠藤力斗、中村孝司、上田智貴、佐藤悠介、原島秀吉
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19448
[Presentation] 腫瘍血管破壊を誘導する新機軸がん治療法の開発2023
- Author(s)
  中村孝司、遠藤力斗、上田智貴、佐藤悠介、原島秀吉
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] がん免疫応答を制御する薬物送達システムの開発2023
- Author(s)
  中村孝司
- Organizer
  徳島大学研究クラスター次世代DDS/iTEX合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K19448
[Presentation] 免疫システムを制御するデリバリー技術2023
- Author(s)
  中村孝司
- Organizer
  国立がん研究センター EPOC/CPOTセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K19448
[Presentation] 腫瘍血管破壊を誘導する新機軸がん治療法の開発2023
- Author(s)
  中村孝司、遠藤力斗、上田智貴、佐藤悠介、原島秀吉
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19448
[Presentation] 免疫システムを制御するデリバリー技術2023
- Author(s)
  中村孝司
- Organizer
  国立がん研究センター EPOC/CPOTセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20H03373
[Presentation] 腫瘍血管内皮細胞の機能制御と自然免疫活性化を起点とした新規がん治療法の開発2023
- Author(s)
  上田智貴、中村孝司、遠藤力斗、佐藤悠介、原島秀吉
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-22K19448
[Presentation] ナノDDSを基盤とした腫瘍血管破壊を誘導する新規がん治療法の開発2023
- Author(s)
  遠藤力斗、中村孝司、上田智貴、佐藤悠介、原島秀吉
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] アジュバント搭載薬物送達システムによる免疫制御2023
- Author(s)
  中村孝司
- Organizer
  第39回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19448
[Presentation] がん免疫療法を加速するナノDDSの開発2022
- Author(s)
  中村孝司
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] 免疫システムを制御する脂質ナノ粒子の開発2022
- Author(s)
  中村孝司
- Organizer
  日本薬物動態学会第37回年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03373
[Presentation] Nano cancer immunotherapy mediated by lipid nanoparticles2022
- Author(s)
  Takashi Nakamura
- Organizer
  The 7th Japan-Taiwan Joint Symposium For Pharmaceutical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] Nano cancer immunotherapy mediated by lipid nanoparticles.2022
- Author(s)
  Takashi Nakamura
- Organizer
  The 7th Japan-Taiwan Joint Symposium For Pharmaceutical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03373
[Presentation] がん免疫療法を加速するナノDDSの開発2022
- Author(s)
  中村孝司
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03373
[Presentation] 免疫システムを制御する脂質ナノ粒子の開発2022
- Author(s)
  中村孝司
- Organizer
  日本薬物動態学会第37回年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] ヒトNK細胞株への効率的なsiRNAデリバリーを可能とする脂質ナノ粒子の開発2021
- Author(s)
  中出泰誠、中村孝司、山田小春、佐藤悠介、原島秀吉
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03373
[Presentation] 脂質をベースとしたナノDDS（リポソーム、脂質ナノ粒子）の設計と評価方法2021
- Author(s)
  中村孝司
- Organizer
  情報機構webセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] リンパ節送達とリンパ節内分布に影響を与える脂質ナノ粒子特性2021
- Author(s)
  中村孝司、河合美典、佐藤悠介、真栄城正寿、渡慶次学、原島秀吉
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20H03373
[Presentation] 低温下での脂質ナノ粒子の免疫細胞表面への結合が引き起こすトランスフェクション活性の消失2021
- Author(s)
  中村孝司、山田小春、佐藤悠介、原島秀吉
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03373
[Presentation] 低温下での脂質ナノ粒子の免疫細胞表面への結合が引き起こすトランスフェクション活性の消失2021
- Author(s)
  中村孝司、山田小春、佐藤悠介、原島秀吉
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] Nucleic Acid Drugs and Nanomedicine: Multifunctional Envelope-type Nano Device for Nanomedicine2020
- Author(s)
  Hideyoshi Harashima, Yusuke Sato, Takashi Nakamura, Yuma Yamada
- Organizer
  The 79 Annual Meeting of the Japanese Cancer Association.
- Invited
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] ナノDDSを利用したがん免疫制御システムの開発2020
- Author(s)
  中村孝司
- Organizer
  DDS（ドラッグデリバリーシステム）/製剤技術ウェビナー
- Invited
- Data Source
  KAKENHI-PROJECT-20H03373
[Presentation] 脂質ナノ粒子のサイズと電荷がリンパ節移行とリンパ節内分布に与える影響2020
- Author(s)
  中村孝司、河合美典、佐藤悠介、真栄城正寿、渡慶次学、原島秀吉
- Organizer
  日本薬学会140年会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] 脂質ナノ粒子の特性がリンパ節送達とリンパ節内分布へ与える影響2020
- Author(s)
  中村孝司、河合美典、佐藤悠介、真栄城正寿、渡慶次学、原島秀吉
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] ナノDDSを利用したがん免疫制御システムの開発2020
- Author(s)
  中村孝司
- Organizer
  DDS（ドラッグデリバリーシステム）/製剤技術ウェビナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] BCG-CWS搭載脂質ナノ粒子の全身投与型がんアジュバントへの応用2020
- Author(s)
  中村孝司、増田秀幸、野間洋輔、原島秀吉
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] Improvement of PD-1 antibody resistance of melanoma lung metastasis by STING agonist loaded lipid nanoparticles2019
- Author(s)
  Saro Takanori, Nakamura Takashi, Takahashi Nomichi, Sato Yusuke, Hyodo Mamoru, Hayakawa Yoshihiro, Harashima Hideyoshi
- Organizer
  Liposome Research Days 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] TLR3 adjuvant-loaded liposome induce robust antitumor activity and reduces systemic inflammation following intravenous administration.2019
- Author(s)
  Haloho S, Nakamura T, Harashima H
- Organizer
  Liposome Research Days 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] siRNA搭載脂質ナノ粒子を用いた樹状細胞のIDO1発現制御と免疫細胞療法への展開2019
- Author(s)
  遠藤力斗、中村孝司、川上今日子、佐藤悠介、原島秀吉
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] ナノDDSを基盤としたがん免疫療法における腫瘍内免疫状態解析の有用性検証2019
- Author(s)
  川上今日子、中村孝司、佐藤悠介、兵藤守、畠山浩人、早川芳宏、原島秀吉
- Organizer
  日本薬学会北海道支部第146回例会
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] Liposomal delivery of TLR3 agonist induces robust antitumor activity without systemic inflammation following intravenous administration.2019
- Author(s)
  Haloho S, Nakamura T, Harashima H.
- Organizer
  The 48th Annual Scientific Meeting of the Australian and New Zealand Society for Immunology (ASI) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01170
[Presentation] ナノDDS技術を利用したがん免疫療法の開発2019
- Author(s)
  中村孝司
- Organizer
  第35回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] STINGアゴニスト搭載脂質ナノ粒子の併用によるメラノーマ肺転移の抗PD-1抗体抵抗性の改善2019
- Author(s)
  佐藤孝紀、中村孝司、高橋直道、佐藤悠介、兵藤守、早川芳宏、原島秀吉
- Organizer
  日本薬学会北海道支部第146回例会
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] ナノDDSを基盤としたがん免疫療法開発における腫瘍微小環境の免疫状態解析の有用性検証2019
- Author(s)
  1.川上今日子、中村孝司、佐藤悠介、兵藤守、畠山浩人、早川芳宏、原島秀吉
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] ナノDDS技術を利用したがん免疫療法の開発2019
- Author(s)
  中村孝司
- Organizer
  第35回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] STINGアゴニスト搭載脂質ナノ粒子によるメラノーマ肺転移の抗PD-1抗体抵抗性の改善2019
- Author(s)
  佐藤孝紀、中村孝司、高橋直道、佐藤悠介、兵藤守、早川芳宏、原島秀吉
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] STINGアゴニスト搭載脂質ナノ粒子を用いた抗PD-1抗体抵抗性メラノーマ肺転移に対するがん免疫療法2019
- Author(s)
  中村孝司、佐藤孝紀、高橋直道、佐藤悠介、兵藤守、早川芳宏、原島秀吉
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19888
[Presentation] がん免疫療法のための核酸医薬DDS技術2019
- Author(s)
  中村孝司
- Organizer
  日本薬剤学会第34年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] 微小化脂質ナノ粒子によるアジュバントのリンパ節送達2018
- Author(s)
  中村孝司、河合美典、佐藤悠介、真栄城正寿、渡慶次学、原島秀吉
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] siRNA搭載脂質ナノ粒子を用いた樹状細胞のIDO発現抑制2018
- Author(s)
  遠藤力斗、中村孝司、佐藤悠介、原島秀吉
- Organizer
  日本薬学会北海道支部第145回例会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] 脂質ナノ粒子を用いたヒトNK細胞株NK-92へのsiRNA導入2018
- Author(s)
  中村孝司、山田小春、藤原優希、佐藤悠介、原島秀吉
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] 脂質ナノ粒子を基盤としたがん免疫療法のためのナノDDS開発2018
- Author(s)
  中村孝司
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15102
[Presentation] ヒトナチュラルキラー細胞株への毒性回避を目指したsiRNA搭載脂質ナノ粒子の開発2018
- Author(s)
  山田小春、中村孝司、藤原優希、佐藤悠介、原島秀吉
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] siRNA搭載脂質ナノ粒子を用いた免疫細胞の遺伝子発現制御2018
- Author(s)
  中村孝司、黒井萌花、山田小春、藤原優希、藁科翔太、佐藤悠介、原島秀吉
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] ポリカチオンを用いたsiRNA搭載脂質ナノ粒子によるヒトNK細胞株への毒性の軽減2018
- Author(s)
  山田小春、中村孝司、藤原優希、佐藤悠介、原島秀吉
- Organizer
  日本薬学会北海道支部第145回例会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] 脂質ナノ粒子を基盤としたがん免疫療法のためのナノDDS開発2018
- Author(s)
  中村孝司
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] 脂質ナノ粒子によるSTING経路活性化を介したがん免疫療法2017
- Author(s)
  高橋直道、中村孝司、佐藤悠介、兵藤守、早川芳宏、原島秀吉
- Organizer
  第33会日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15102
[Presentation] Cancer immunotherapy by STING ligand loaded lipid nanoparticles2017
- Author(s)
  Naomichi Takahashi, Takashi Nakamura, Yusuke Sato, Mamoru Hyodo, Yoshihiro Hayakawa, Hideyoshi Harashima
- Organizer
  The 36th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15102
[Presentation] リンパ節内樹状細胞を標的とした極小ナノキャリアシステムの開発2017
- Author(s)
  河合美典、中村孝司、佐藤悠介、真栄城正寿、渡慶次学、原島秀吉
- Organizer
  第33会日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03974
[Presentation] STINGリガンド搭載ナノDDSを基盤としたがん免疫療法2017
- Author(s)
  中村孝司、高橋直道、宮部寛子、佐藤悠介、兵藤守、早川芳宏、原島秀吉
- Organizer
  第21回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-16K15102
[Presentation] STINGリガンド搭載脂質ナノ粒子を用いたがん免疫療法2017
- Author(s)
  高橋直道、中村孝司、佐藤悠介、兵藤守、早川芳宏、原島秀吉
- Organizer
  日本薬学会北海道支部第144回例会
- Data Source
  KAKENHI-PROJECT-16K15102
[Presentation] 脂質ナノ粒子を用いたヒト免疫細胞株への効率的siRNA導入2016
- Author(s)
  中村孝司、黒井萌花、藤原優希、藁科翔太、佐藤悠介、原島秀吉
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ（静岡県・静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-26713002
[Presentation] STING ligand loaded lipid nanoparticles enhance cancer immunotherapy2016
- Author(s)
  Takashi Nakamura, Hiroko Miyabe, Mamoru Hyodo, Yusuke Sato, Yoshihiro Hayakawa, Hideyoshi Harashima
- Organizer
  3rd International Conference on Biomaterials Science
- Place of Presentation
  東京大学伊藤国際学術センター（東京都・文京区）
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15102
[Presentation] ナノテクノロジーで制御するがんアジュバントシステムの創製2016
- Author(s)
  中村孝司
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場・岐阜都ホテル（岐阜県・岐阜市）
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-26713002
[Presentation] ナノテクノロジーで制御するがんアジュバントシステムの創製2016
- Author(s)
  中村孝司
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場・岐阜都ホテル（岐阜県・岐阜市）
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-16K15102
[Presentation] 樹状細胞への効率的siRNAデリバリーシステムの開発2015
- Author(s)
  中村孝司、藁科翔太、佐藤悠介、兵藤守、畠山浩人、原島秀吉
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール・長崎新聞文化ホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26713002
[Presentation] がん免疫療法を促進するDrug Delivery Systemの開発2015
- Author(s)
  中村孝司
- Organizer
  日本薬学会北海道支部第142回例会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-05-16
- Invited
- Data Source
  KAKENHI-PROJECT-26560231
[Presentation] がん免疫療法を促進するDrug Delivery Systemの開発2015
- Author(s)
  中村孝司
- Organizer
  日本薬学会北海道支部第142回例会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-05-16
- Invited
- Data Source
  KAKENHI-PROJECT-26713002
[Presentation] BCG-CWS搭載ナノ粒子の抗膀胱がん作用機序2014
- Author(s)
  中村孝司、吹上雅文、鈴木嘉晃、矢野郁也、宮崎淳、西山博之、赤座英之、原島秀吉
- Organizer
  第7回BCG注入療法研究会
- Place of Presentation
  東京　如水会館
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-26560231
[Presentation] オクタアルギニン修飾ナノ粒子によるNKT細胞を介した癌免疫療法の増強2014
- Author(s)
  中村孝司、山崎大樹、山内順、原島秀吉
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] オクタアルギニン修飾ナノ粒子によるNKT細胞を介した癌免疫療法の増強2014
- Author(s)
  中村孝司、山崎大樹、山内順、原島秀吉
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本　熊本大学
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] The nanoparticulation of α-galactosylceramide by octaarginine-modified liposome enhances α-galactosylceramide mediated antitumor effects in an experimental lung metastasis model2013
- Author(s)
  Nakamura T, Yamazaki D, Yamauchi J, Harashima H
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center, Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] オクタアルギニン修飾ナノ粒子によるNKT細胞を介した抗腫瘍免疫の促進2013
- Author(s)
  中村孝司、山崎大樹、山内順、原島秀吉
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋　ウインクあいち
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] オクタアルギニン修飾ナノ粒子によるNKT細胞を介した抗腫瘍免疫の促進2013
- Author(s)
  中村孝司、山崎大樹、山内順、原島秀吉
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] The nanoparticulation ofα-galactosylceramide by octaarginine-modified liposome enhancesα-galactosylceramide mediated antitumor effects in an experimental lung metastasis model2013
- Author(s)
  Nakamura T, Yamazaki D, Yamauchi J, Harashima H
- Organizer
  40^<th> Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] Delivery system for cancer immunotherapy2013
- Author(s)
  Nakamura T
- Organizer
  The 16th SNU-HU JOINT SYMPOSIUM
- Place of Presentation
  Seoul National University, Soul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] α-Galactosylceramide incorporated octaarginine-modified nanoparticles inhibit experimental tumor metastasis2012
- Author(s)
  Yamazaki Daiki, Nakamura Takashi, Harashima Hideyoshi
- Organizer
  第41回　日本免疫学会総会
- Place of Presentation
  神戸国際会議場、神戸国際展示場、神戸ポートピアホテル（兵庫県）
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] α-Galactosylceramide incorporated octaarginine-modified nanoparticles inhibit experimental tumor metastasis2012
- Author(s)
  Yamazaki D, Nakamura T, Harashima H
- Organizer
  第41回日本免疫学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790037
[Presentation] BCG-CWS搭載ナノ粒子を用いた膀胱がん免疫療法剤の開発
- Author(s)
  中村孝司、吹上雅文、鈴木嘉晃、矢野郁也、宮崎淳、西山博之、赤座英之、中山俊憲、原島秀吉
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸　神戸学院大学　兵庫医療大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26713002
[Presentation] 免疫応答の増強を可能とするエンドソーム脱出促進型siRNAナノキャリアの開発
- Author(s)
  藁科翔太、中村孝司、佐藤悠介、兵藤守、畠山浩人、原島秀吉
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島　徳島大学
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-26713002
[Presentation] BCG-CWS搭載ナノ粒子を用いた膀胱がん免疫療法剤の開発
- Author(s)
  中村孝司、吹上雅文、鈴木嘉晃、矢野郁也、宮崎淳、西山博之、赤座英之、中山俊憲、原島秀吉
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸　神戸学院大学　兵庫医療大学
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26560231

1. HARASHIMA Hideyoshi (00183567)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
2. 山田勇磨 (60451431)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. 佐藤悠介 (10735624)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. SUGITA Masahiko (80333532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. IGARASHI Tatuhiko (90467431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 兵藤守 (30548186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 馬場嘉信 (30183916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 篠原康雄 (60226157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小暮健太朗 (70262540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 紙谷浩之 (10204629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 渡慶次学 (60311437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 松尾保孝 (90374652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 秋田英万 (80344472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 西山伸宏 (10372385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 内田智士 (20710726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 石垣和慶 (00790338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 山野友義 (40724183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山下匡 (30220338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 永根大幹 (10772064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 白川利朗 (70335446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 植木秀登 (00903296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 畠山浩人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Takashi 中村 孝司

NAKAMURA Takashi 中村 孝司

Research Projects

Research Products

Co-Researchers

Development of a novel oncolytic viral therapy targeting cancer stem cell for muscle-invasive bladder cancer

Principal Investigator

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メモリー様NK細胞を駆動する新たなナノがん免疫療法の開拓Principal Investigator

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ナノDDSによる生体内機能強化NK細胞の創出と新規がん免疫療法基盤の構築Principal Investigator

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Activated mRNA delivery system based on core-shell structured LNP with smart polymers

Principal Investigator

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炎症性腸疾患におけるスフィンゴ糖脂質による治療を目指した基礎的研究

Principal Investigator

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ナノDDSで挑む腫瘍血管内皮細胞を標的とした新機軸のがん治療法の開発Principal Investigator

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Nano cancer immunotherapy using memory NK cells against PD-1 blockade resistant tumorPrincipal Investigator

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Innovative gene/nucleic acid delivery system based on optimized intracellular trafficking steps

Principal Investigator

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Development of nano cancer immunotherapy based on immune status in tumorPrincipal Investigator

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Combined immunotherapy based on nano-DDS targeting tumor draining lymph nodesPrincipal Investigator

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Combined cancer immunotherapy of PD-1 antibody and c-di-GMP loaded lipid nanoparticlesPrincipal Investigator

Principal Investigator

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Lipid immunity in rhesus monkeys and development of a new anti-tuberculosis vaccine

Principal Investigator

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Research Institution

The effect of intracellular trafficking of BCG-CWS loaded nanoparticles on anti-bladder cancer activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Nakamura Takashi 中村孝司

NAKAMURA Takashi 中村孝司