YAMAUCHI Shota 山内翔太

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Yamauchi Shota 山内翔太

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Researcher Number	00728941
Other IDs
Affiliation (Current)	2025: 公益財団法人がん研究会, がん研究所細胞老化研究部, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 助教 2018 – 2019: 東京大学, 大学院薬学系研究科(薬学部), 特任助教 2016: 福井大学, 学術研究院医学系部門, 特命助教 2014 – 2016: 福井大学, 医学部, 特命助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Pathological medical chemistry Except Principal Investigator Pathological medical chemistry
Keywords	Principal Investigator 細胞老化 / DNA損傷応答 / 代謝 / ミトコンドリア / チロシンキナーゼ / ウイルス-宿主相互作用 / インターフェロン / C型肝炎ウイルス Except Principal Investigator チロシンキナーゼ / C型肝炎ウイルス

細胞老化におけるミトコンドリアDNA損傷応答Principal Investigator
- Principal Investigator
  
  山内翔太
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokyo
Role of mitochondrial metabolic changes in the regulation of gene expression during senescencePrincipal Investigator
- Principal Investigator
  
  Yamauchi Shota
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokyo
Identification of genes involved in the expression of the cellular senescence marker p16INK4aPrincipal Investigator
- Principal Investigator
  
  Yamauchi Shota
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokyo
Tyrosine phosphorylation of a viral protein in the hepatitis C virus life cyclePrincipal Investigator
- Principal Investigator
  
  Yamauchi Shota
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Fukui
Role of the regulation of B cell protein-tyrosine kinase by hepatitis C virus
- Principal Investigator
  
  SADA Kiyonao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Fukui

All 2023 2022 2016 2015 2014

All Journal Article Presentation

[Journal Article] STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-lambda but not by interferon-alpha2016
- Author(s)
  Yamauchi, S., Takeuchi, K., Chihara, K., Honjoh, C., Kato, Y., Yoshiki, H., Hotta, H., and Sada, K.
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 38336-38336
- DOI
  10.1038/srep38336
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19021
[Journal Article] Hepatitis C virus particle assembly involves phosphorylation of NS5A by the c-Abl tyrosine kinase2015
- Author(s)
  Yamauchi, S., Takeuchi, K., Chihara, K., Sun, X., Honjoh, C., Yoshiki, H., Hotta, H., and Sada, K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 36 Pages: 21857-21864
- DOI
  10.1074/jbc.m115.666859
- NAID
  120005973616
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19021, KAKENHI-PROJECT-25460383
[Journal Article] Dectin-1-mediated signaling leads to characteristic gene expressions and cytokine secretion via spleen tyrosine kinase (Syk) in rat mast cells.2014
- Author(s)
  Kimura Y, Chihara K, Honjoh C, Takeuchi K, Yamauchi S, Yoshiki H, Fujieda S, Sada K
- Journal Title
  
  J Biol Chem.
  
  Volume: 289 Issue: 45 Pages: 31565-75
- DOI
  10.1074/jbc.m114.581322
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293348, KAKENHI-PROJECT-25460383, KAKENHI-PROJECT-26293368
[Journal Article] Tyrosine phosphorylation of 3BP2 is indispensable for the interaction with Vav3 in chicken DT40 cells2014
- Author(s)
  Chihara, K., Kimura, Y., Honjoh, C., Yamauchi, S., Takeuchi, K., Sada, K.
- Journal Title
  
  Exp. Cell Res.
  
  Volume: 322 Issue: 1 Pages: 99-107
- DOI
  10.1016/j.yexcr.2013.12.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591105, KAKENHI-PROJECT-25460383
[Presentation] 細胞老化におけるミトコンドリア代謝リプログラミングの役割2023
- Author(s)
  山内翔太　一條秀憲
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-21K06061
[Presentation] DNA損傷応答シグナルはミトコンドリア代謝のリモデリングにより細胞老化を誘導する2022
- Author(s)
  山内翔太
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-21K06061
[Presentation] Role of NS5A tyrosine phosphorylation in hepatitis C virus particle assembly2015
- Author(s)
  Yamauchi, S., Takeuchi, K., Chihara, K., Sun, X., Honjoh, C., Yoshiki, H., Hotta, H., and Sada, K.
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-23
- Data Source
  KAKENHI-PROJECT-15K19021
[Presentation] C型肝炎ウイルス粒子形成におけるc-Ablの役割2015
- Author(s)
  山内翔太, 竹内健司, 千原一泰, 孫雪東, 本定千知, 吉木はつみ, 堀田博, 定清直
- Organizer
  BMB2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25460383
[Presentation] アダプター蛋白質3BP2は分化したAML細胞においてSrc型チロシンキナーゼの活性化を促進する2015
- Author(s)
  千原一泰，吉木はつみ，加藤雄士，本定千知，山内翔太，竹内健司，定清直
- Organizer
  BMB2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25460383
[Presentation] チロシンキナーゼによるHCV複製の制御機構2015
- Author(s)
  山内翔太
- Organizer
  第33回日本生化学会北陸支部大会
- Place of Presentation
  富山
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-15K19021
[Presentation] マスト細胞におけるC型レクチンMincleの機能解析2015
- Author(s)
  本定千知, 千原一泰, 吉木はつみ, 山内翔太, 竹内健司, 飛田征男, 岩野正之, 石塚全, 定清直
- Organizer
  日本生化学会北陸支部第33回大会
- Place of Presentation
  富山
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-25460383
[Presentation] マスト細胞におけるC型レクチンMincleの機能解析2015
- Author(s)
  本定千知, 千原一泰, 吉木はつみ, 山内翔太, 竹内健司, 飛田征男, 岩野正之, 石塚全, 定清直
- Organizer
  BMB2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25460383
[Presentation] チロシンキナーゼによるHCV複製の制御機構2015
- Author(s)
  山内翔太, 竹内健司, 千原一泰, 孫雪東, 本定千知, 吉木はつみ, 堀田博, 定清直
- Organizer
  日本生化学会北陸支部第33回大会, シンポジウム「病原性ウイルス・免疫応答研究の最前線」
- Place of Presentation
  富山
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-25460383
[Presentation] Role of c-Abl in hepatitis C virus particle assembly2015
- Author(s)
  Yamauchi, S., Takeuchi, K., Chihara, K., Sun, X., Honjoh, C., Yoshiki, H., Hotta, H., and Sada, K.
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K19021
[Presentation] マスト細胞におけるDectin-1の機能解析：真菌感染防御におけるマスト細胞の新たな役割．2014
- Author(s)
  千原一泰，木村幸弘，本定千知，吉木はつみ，山内翔太，竹内健司，定　清直．
- Organizer
  日本生化学会北陸支部第32回大会
- Place of Presentation
  富山大学杉谷キャンパス
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25460383

1. SADA Kiyonao (10273765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. CHIHARA Kazuyasu (00314948)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. TAKEUCHI Kenji (40236419)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
4. HOTTA Hak (40116249)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. 藤枝重治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAUCHI Shota 山内 翔太

Yamauchi Shota 山内 翔太

Research Projects

Research Products

Co-Researchers

細胞老化におけるミトコンドリアDNA損傷応答Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of mitochondrial metabolic changes in the regulation of gene expression during senescencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of genes involved in the expression of the cellular senescence marker p16INK4aPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tyrosine phosphorylation of a viral protein in the hepatitis C virus life cyclePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of the regulation of B cell protein-tyrosine kinase by hepatitis C virus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-lambda but not by interferon-alpha2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hepatitis C virus particle assembly involves phosphorylation of NS5A by the c-Abl tyrosine kinase2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Dectin-1-mediated signaling leads to characteristic gene expressions and cytokine secretion via spleen tyrosine kinase (Syk) in rat mast cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tyrosine phosphorylation of 3BP2 is indispensable for the interaction with Vav3 in chicken DT40 cells2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 細胞老化におけるミトコンドリア代謝リプログラミングの役割2023

Author(s)

Organizer

Data Source

[Presentation] DNA損傷応答シグナルはミトコンドリア代謝のリモデリングにより細胞老化を誘導する2022

Author(s)

Organizer

Data Source

[Presentation] Role of NS5A tyrosine phosphorylation in hepatitis C virus particle assembly2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] C型肝炎ウイルス粒子形成におけるc-Ablの役割2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] アダプター蛋白質3BP2は分化したAML細胞においてSrc型チロシンキナーゼの活性化を促進する2015

Author(s)

Organizer

Place of Presentation

YAMAUCHI Shota 山内翔太

Yamauchi Shota 山内翔太