FUJIHARA CHIHARU 藤原千春

Researcher Number	00755358
Other IDs	https://orcid.org/0000-0003-0556-9530
Affiliation (Current)	2025: 大阪大学, 歯学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪大学, 大学院歯学研究科, 助教 2017 – 2021: 大阪大学, 歯学研究科, 助教 2015 – 2016: 大阪大学, 歯学研究科, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Medium-sized Section 57:Oral science and related fields / Basic Section 57030:Conservative dentistry-related / Periodontology Except Principal Investigator Basic Section 57030:Conservative dentistry-related / Medium-sized Section 57:Oral science and related fields / Periodontology
Keywords	Principal Investigator 歯周病 / 数理モデル / ミトコンドリア / オミクス解析 / RNAシークエンス / 遺伝子発現 / 歯周組織再生 / 歯根膜細胞 / CD40 / エネルギー代謝 … More / 生物時計 / 分化 / 単球 / オミクス / 病態遷移 / 遺伝子発現データ / p-dentistry / 予防 / 遺伝子発現解析 / マウス歯周病細菌叢 / オミックス解析 / 重症化予測 / 歯周病進行経路 / 歯槽骨吸収 / 細菌叢解析 / マウスモデル / マイクロバイオーム / 歯周病重症化予測 / 再生効果 / 再生機構 / 歯周組織 / 歯周組織構成細胞 / CD40L / 骨リモデリング / メカニカルストレス / CD40-CD40L相互作用 / 炎症反応 / セメント芽細胞 / 免疫 / 歯周炎 / コンディショナルノックアウトマウス / 骨代謝 / B細胞 … More Except Principal Investigator 歯周組織再生 / 歯根膜 / 侵襲性歯周炎 / 歯周病 / 歯根膜細胞 / シングルセル解析技 / シングルセル解析 / シングルセル解析技術 / オープンクロマチン領域 / scATAC-seq / 低フォスファターゼ症 / 歯周組織再生療法 / セメント芽細胞 / モルフォゲン勾配 / 空間トランスクリプトーム / FPR2 / 遺伝子解析 / オミックス解析 / 多因子 / 口唇口蓋裂 / プロテオーム解析 / メタボローム解析 / オミクス解析 / ゲノムワイドアプローチ / CLSPN / LIPA / 疾患関連遺伝子 / エクソームシークエンス / SNP / GWAS / エクソームシークエンス解析 / コンピテンシー / 脂肪組織由来多系統前駆細胞 / 再生医療 / 幹細胞移植 / 歯周病学 / 歯周組織恒常性維持 / 歯周組織恒常性維持機構 / 遺伝子改変マウス / senolytic / NAD+中間代謝産物 / 時計遺伝子 / NAMPT / SIRT / 時間制御 / 老化制御 / 老化細胞 / ミトコンドリア / NMN / NAD+依存性 / 細胞老化 Less

モルフォゲン勾配を介した歯周組織再生機序の解明と応用
- Principal Investigator
  
  竹立匡秀
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
セメント芽細胞分化の制御機構解明に向けた新展開
- Principal Investigator
  
  村上伸也
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
数理モデルに基づく歯周病の病態遷移機序の解明Principal Investigator
- Principal Investigator
  
  藤原千春
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
生物時計制御に基づく歯周組織再生効率の向上Principal Investigator
- Principal Investigator
  
  藤原千春
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
New Strategies in Cleft Lip and Palate Research through Multifactorial Trans-Omics Analysis
- Principal Investigator
  
  INUBUSHI TOSHIHIRO
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
歯周病におけるFPR2シグナルを介した炎症収束機構の解明
- Principal Investigator
  
  森本千晶
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
細胞ダイバーシティーを基盤とした歯周組織幹細胞の運命決定機構の解明
- Principal Investigator
  
  岩山智明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Developing prediction of periodontal disease to realize p-dentistryPrincipal Investigator
- Principal Investigator
  
  Fujihara Chiharu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Prediction of periodontal disease progression by a mathematical modelPrincipal Investigator
- Principal Investigator
  
  Fujihara Chiharu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Elucidation of mechanisms of regeneration of periodontal tissue by mathematical modellingPrincipal Investigator
- Principal Investigator
  
  Fujihara Chiharu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Understanding of pathogenesis of aggressive periodontitis by omics data
- Principal Investigator
  
  Shinya Murakami
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Extension of healthy longevity in body and periodontal tissue by NMN supplementation and senolytic treatment
- Principal Investigator
  
  YAMASHITA MOTOZO
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Elucidation of stem cell competencies for periodontal tissue regeneration and application to cell transplantation therapy
- Principal Investigator
  
  Takedachi Masahide
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Study of the interaction of CD40-CD40L in periodontal tissuePrincipal Investigator
- Principal Investigator
  
  FUJIHARA CHIHARU
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Osaka University
Homeodynamics analysis of periodontal ligament tissue
- Principal Investigator
  
  Yamada Satoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  Tohoku University
Analysis of bone metabolism in B cell-specific CD40 conditional knockoout micePrincipal Investigator
- Principal Investigator
  
  FUJIHARA CHIHARU
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontology
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] 歯根膜細胞の骨芽細胞分化におけるカテプシン A の影響 .2023
- Author(s)
  北垣次郎太,松本昌大,藤原千春,阪下裕美,平井麻絵,山下元三,北村正博,村上伸也
- Journal Title
  
  日本歯科保存学雑誌
  
  Volume: 66 Pages: 214-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K27771
[Journal Article] Lysosomal acid lipase regulates bioenergetic process during the cytodifferentiation of human periodontal ligament cells2023
- Author(s)
  Teerachate Nantakeeratipat, Chiharu Fujihara, Takuto Nogimori, Masahiro Matsumoto, Takuya Yamamoto, Shinya Murakami
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 662 Pages: 84-92
- DOI
  10.1016/j.bbrc.2023.04.041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19595, KAKENHI-PROJECT-19H01069, KAKENHI-PROJECT-20H03864, KAKENHI-PROJECT-23K18359
[Journal Article] Omics-Based Mathematical Modeling Unveils Pathogenesis of Periodontitis in an Experimental Murine Model2023
- Author(s)
  Fujihara C, Murakami K, Magi S, Motooka D, Nantakeeratipa N, Canela A, Tanaka RJ, Okada M, Murakami S
- Journal Title
  
  J Dent Res
  
  Volume: 102 (13) Pages: 1468-1477
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27771
[Journal Article] Identification of disease-associate variants of aggressive periodontitis using genome-wide association studies2023
- Author(s)
  Fujihara Chiharu、Hafiyyah Osa Amila、Murakami Shinya
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: 59 Pages: 357-364
- DOI
  10.1016/j.jdsr.2023.09.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00437, KAKENHI-PROJECT-23K27771
[Journal Article] CD40-CD40 ligand interaction between periodontal ligament cells and cementoblasts enhances periodontal tissue remodeling in response to mechanical stress.2023
- Author(s)
  Yamamoto Y, Fujihara C, Nantakeeratipat T, Matsumoto M, Noguchi T, Kitagawa M, Yamada S, Takata T, Kitaura H, Murakami S.
- Journal Title
  
  J Periodontal Res.
  
  Volume: 58(6) Issue: 6 Pages: 1261-1271
- DOI
  10.1111/jre.13182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18359, KAKENHI-PROJECT-22K10236, KAKENHI-PROJECT-22K17223
[Journal Article] Energy metabolism in osteogenic differentiation and reprogramming: A strategy for periodontal regeneration.2022
- Author(s)
  C Fujihara, T Nantakeeratipat, S Murakami
- Journal Title
  
  Front Dent Med
  
  Volume: 3 Pages: 815140-815140
- DOI
  10.3389/fdmed.2022.815140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01069, KAKENHI-PROJECT-20H03864
[Journal Article] Lipase-a single-nucleotide polymorphism rs143793106 is associated with increased risk of aggressive periodontitis by negative influence on the cytodifferentiation of human periodontal ligament cells2022
- Author(s)
  Masahiro Matsumoto, Chiharu Fujihara, Teerachate Nantakeeratipa, Jirouta Kitagaki, Yu Yamamoto, Satoru Yamada, Masahiro Kitamura, Shinya Murakami
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 00 Issue: 1 Pages: 1-9
- DOI
  10.1111/jre.13079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19595, KAKENHI-PROJECT-19H01069, KAKENHI-PROJECT-20H03864, KAKENHI-PROJECT-22K17035
[Journal Article] 歯周病新分類の解釈とその応用2022
- Author(s)
  村上伸也、藤原千春、岩山智明
- Journal Title
  
  日本臨床歯周病学会会誌39(2)
  
  Volume: 39(2) Pages: 20-26
- Data Source
  KAKENHI-PROJECT-19H01069
[Journal Article] Periodontal tissue regeneration by transplantation of autologous adipose tissue-derived multi-lineage progenitor cells2022
- Author(s)
  Takedachi Masahide、Sawada Keigo、Sakura Kazuma、Morimoto Chiaki、Hirai Asae、Iwayama Tomoaki、Shimomura Junpei、Kawasaki Kohsuke、Fujihara Chiharu、Kashiwagi Yoichiro、Miyake Akimitsu、Yamada Tomomi、Okura Hanayuki、Matsuyama Akifumi、Saito Masahiro、Kitamura Masahiro、Murakami Shinya
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 8126-8126
- DOI
  10.1038/s41598-022-11986-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09964, KAKENHI-PROJECT-21K19587, KAKENHI-PROJECT-21H03116, KAKENHI-PROJECT-20K09936
[Journal Article] 歯周病新分類の解釈とその応用2021
- Author(s)
  村上伸也、藤原千春、岩山智明
- Journal Title
  
  日本臨床歯周病学会会誌
  
  Volume: 39(2) Pages: 20-26
- Data Source
  KAKENHI-PROJECT-20H03864
[Journal Article] 歯の早期喪失と老後のQOL、認知機能、生命予後等の関連性を縦断的に追跡調査可能とするための新たな診断法の開発と罹患率のパイロット調査2021
- Author(s)
  藤原千春、北垣次郎太、桝本梨沙、松本昌大、山本　優、村上伸也
- Journal Title
  
  日本歯科医学会誌
  
  Volume: 40 Pages: 49-54
- Data Source
  KAKENHI-PROJECT-19H01069
[Journal Article] Association of periodontal disease with atherosclerosis in 70-year-old Japanese older adults2020
- Author(s)
  Kitamura M, Ikebe K, Kamide K, Gondo Y, Yamashita M, Takedachi M, Nozaki T, Fujihara C, Yamada S, Kashiwagi Y, Miki K, Iwayama T, Hatta K, Mihara Y, Kurushima Y et al
- Journal Title
  
  Odontology
  
  Volume: 109 Issue: 2 Pages: 506-513
- DOI
  10.1007/s10266-020-00567-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982, KAKENHI-PROJECT-19H01069
[Journal Article] Fibroblast growth factor-2 inhibits CD40-mediated periodontal inflammation.2019
- Author(s)
  Fujihara C*, Kanai Y, Masumoto R, Kitagaki J, Matsumoto M, Yamada S, Kajikawa T, Murakami S
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 234(5) Issue: 5 Pages: 7149-7160
- DOI
  10.1002/jcp.27469
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17349, KAKENHI-PROJECT-19K22714
[Journal Article] Response to "Genetics of Periodontitis without Bias".2019
- Author(s)
  Masumoto R, Kitagaki J, Fujihara C, Matsumoto M, Miyauchi S, Asano Y, Imai A, Kobayashi K, Nakaya A, Yamashita M, Yamada S, Kitamura M, Murakami S
- Journal Title
  
  The Journal of Periodontal Research
  
  Volume: 54(5) Issue: 5 Pages: 455-456
- DOI
  10.1111/jre.12652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01069
[Journal Article] Identification of genetic risk factors of aggressive periodontitis using genomewide association studies in association with those of chronic periodontitis.2018
- Author(s)
  Masumoto R, Kitagaki J, Fujihara C*, Matsumoto M, Miyauchi S, Asano Y, Imai A, Kobayashi K, Nakaya A, Yamashita M, Yamada S, Kitamura M, Murakami S
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: - Issue: 3 Pages: 12620-12620
- DOI
  10.1111/jre.12620
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17349, KAKENHI-PROJECT-18K19547
[Presentation] 歯周病進行過程におけるCCL2の時空間的発現変化2023
- Author(s)
  藤原千春、村上伸也
- Organizer
  2023年度秋季日本歯科保存学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27771
[Presentation] Non-synergistic interaction between periodontal pathogens and Ccl2 in periodontitis progression2023
- Author(s)
  Fujihara C, Murakami S
- Organizer
  第71回国際歯科研究学会日本部会(JADR)総会・学術大会
- Data Source
  KAKENHI-PROJECT-23K27771
[Presentation] オミクス解析と数理モデリングによる歯周病進行の病態理解と口腔疾患解明への展望2023
- Author(s)
  藤原千春
- Organizer
  広島大学
- Invited
- Data Source
  KAKENHI-PROJECT-23K27771
[Presentation] The localization and timing of MCP-1 expression during periodontitis progression2023
- Author(s)
  Fujihara C, Murakami S
- Organizer
  102th General Session & Exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27771
[Presentation] 脂質代謝を介した歯根膜細胞の硬組織形成細胞への分化におけるエネルギー供給機構の解明2023
- Author(s)
  藤原千春、Nantakeeratipat T, 村上伸也
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K18359
[Presentation] リソソーム酸性リパーゼを介した脂質代謝による歯根膜細胞の分化制御機構の解明2023
- Author(s)
  藤原千春、Nantakeeratipat T, 村上伸也
- Organizer
  第44回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-23K18359
[Presentation] 数理モデルを用いた歯周病重症化の病因解明2022
- Author(s)
  藤原　千春、Teerachate Nantakeeratipat, 井元　宏明、岡田　眞里子、村上　伸也
- Organizer
  第43回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-20H03864
[Presentation] 歯周病における歯槽骨吸収に影響を及ぼす要因の検討2022
- Author(s)
  藤原千春、村上伸也
- Organizer
  第157回日本歯科保存学会学術大会秋季大会
- Data Source
  KAKENHI-PROJECT-21K19595
[Presentation] 数理モデルを用いた歯周病進行の病態理解2022
- Author(s)
  藤原千春、村上伸也
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03864
[Presentation] 歯周病における歯槽骨吸収に影響を及ぼす要因の検討2022
- Author(s)
  藤原千春、村上伸也
- Organizer
  第157回日本歯科保存学会学術大会秋季大会
- Data Source
  KAKENHI-PROJECT-20H03864
[Presentation] Elucidation of pathogenesis of periodontal disease using a mathematical modeling2021
- Author(s)
  Chiharu Fujihara
- Organizer
  the 2nd Ankara-Osaka University Dental Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03864
[Presentation] 日本人侵襲性歯周炎の疾患関連遺伝子LIPA SNP rs14379316のヒト歯根膜細胞における機能解析2021
- Author(s)
  松本　昌大、藤原　千春、北垣　次郎太、Teerachate Nantakeeratipat、桝本　梨沙、山本　優、村上　伸也
- Organizer
  第155回秋季日本歯科保存学会
- Data Source
  KAKENHI-PROJECT-19H01069
[Presentation] 日本人侵襲侵襲炎疾患関連遺伝子Claspinのヒト歯根膜細胞における機能解析2021
- Author(s)
  Teerachate Nantakeeratipat、藤原　千春、松本　昌大、桝本　梨沙、山本　優、北垣　次郎太、北村　正博、村上　伸也
- Organizer
  第154回春季日本歯科保存学会
- Data Source
  KAKENHI-PROJECT-19H01069
[Presentation] Lipolysis Is Involved in Cytodifferentiation of Human Periodontal Ligament Cells2021
- Author(s)
  Teerachate Nantakeeratipat, Chiharu Fujihara, Masahiro Matsumoto, Risa Masumoto, Yu Yamamoto, Jirouta Kitagaki, Shinya Murakami
- Organizer
  The 2021 IADR/AADR/CADR General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01069
[Presentation] 遺伝子多型解析から侵襲性歯周炎を再考する2020
- Author(s)
  藤原　千春
- Organizer
  日本歯周病学会　第５回近畿地区（滋賀）臨床研修会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01069
[Presentation] Paraoxonase-1, a risk factor of Aggressive Periodontitis2020
- Author(s)
  Masumoto R, Fujihara C, Matsumoto M, Kitagaki J, Murakami S
- Organizer
  The 98th General Session of the International Association of Dental Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01069
[Presentation] 日本人侵襲性歯周炎の疾患関連遺伝子Paraoxonase-1の機能解析2020
- Author(s)
  枡本梨沙, 藤原千春, 松本昌大, 山本優, 北垣次郎太, 北村正博, 村上伸也
- Organizer
  第153回秋季日本歯科保存学会学術大会
- Data Source
  KAKENHI-PROJECT-19H01069
[Presentation] Identification of genetic risk factors of aggressive periodontitis in the Japanese population2020
- Author(s)
  Teerachate Nantakeeratipat, 藤原千春, 松本昌大, 桝本梨沙, 北垣次郎太, 山本優, 木下茉優, 北村正博, 村上伸也
- Organizer
  第63回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19H01069
[Presentation] 侵襲性歯周炎の遺伝子多型を考える2020
- Author(s)
  藤原　千春
- Organizer
  日本歯周病学会　臨床研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22714
[Presentation] Building a mathematical model of periodontal disease2020
- Author(s)
  Teerachate Nantakeeratipat, Chiharu Fujihara, Johannes Nicolaus Wibisana, Hiroaki Imoto, Keita Iida, Mariko Okada and Shinya Murakami
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03864
[Presentation] オミクス解析を用いた歯周病による組織破壊機構の理解2020
- Author(s)
  藤原千春, Teerachate Nantakeeratipat, Wibisana, Johannes Nicolaus, 飯田渓太, 井元宏明, 岡田眞里子、村上伸也
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03864
[Presentation] 歯周組織再生過程におけるFibroblast Growth Factor-2 (FGF-2) の抗炎症作用2019
- Author(s)
  藤原千春、金井　優、桝本梨沙、松本昌大、村上伸也
- Organizer
  第四回日本骨免疫学会ウィンターセミナー
- Data Source
  KAKENHI-PROJECT-17K17349
[Presentation] CD40-CD40Lクロストークによる歯周組織の炎症と再生誘導機構2019
- Author(s)
  藤原　千春
- Organizer
  第61回日本歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22714
[Presentation] ノックアウトマウスを用いたPLAP-1の歯根膜機械的機能解析2019
- Author(s)
  木下昌毅1、山田聡、藤原千春、佐々木淳一、下村純平、川嵜公輔　川村聡子、粟田敏仁、津島賢一朗、竹立匡秀、村上伸也
- Organizer
  日本歯周病学会
- Data Source
  KAKENHI-PROJECT-17H04417
[Presentation] 細胞特異的CD40コンディショナルノックアウトマウスを用いた骨代謝機能解析2018
- Author(s)
  藤原千春、金井　優、北垣次郎太、山田　聡、村上伸也
- Organizer
  第三回日本骨免疫学会ウィンターセミナー
- Data Source
  KAKENHI-PROJECT-17K17349
[Presentation] 細胞特異的 CD40 分子が骨恒常性維持機構に及ぼす影響2018
- Author(s)
  藤原千春、金井優、北垣次郎太、山田聡,村上伸也
- Organizer
  日本歯科保存学会春季学術大会（第148回）
- Data Source
  KAKENHI-PROJECT-17K17349
[Presentation] FGF-2 suppressed CD40-mediated inflammation in periodontal ligament cells2018
- Author(s)
  C. Fujihara, Y. Kanai, S. Murakami
- Organizer
  96th General Session and Exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17349
[Presentation] B細胞特異的CD40コンディショナルノックアウトマウスを用いた骨代謝解析2018
- Author(s)
  藤原　千春、金井　優、北垣次郎太、山田　聡、村上　伸也
- Organizer
  第3回日本骨免疫学ウィンターセミナー
- Data Source
  KAKENHI-PROJECT-17K17349
[Presentation] ノックアウトマウスを用いたPLAP-1の歯周組織における機能解析2018
- Author(s)
  木下昌毅、山田　聡、藤原千春、川村聡子、粟田敏仁、津島賢一朗、竹立匡秀、村上伸也
- Organizer
  日本歯周病学会
- Data Source
  KAKENHI-PROJECT-17H04417
[Presentation] FGF-2は歯根膜細胞上のCD40の発現を抑制し炎症反応を抑制する2017
- Author(s)
  藤原千春、山田　聡、北垣次郎太、村上伸也
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-17K17349
[Presentation] CD40分子が誘導するダイナミックな生体機能2017
- Author(s)
  藤原千春
- Organizer
  第二回口腔医科学フロンティア
- Place of Presentation
  Zaoセンタープラザ (山形県上山市)
- Year and Date
  2017-03-05
- Invited
- Data Source
  KAKENHI-PROJECT-15H06391
[Presentation] CD40分子が誘導するダイナミックな生態機能ー全身における免疫機能制御から歯周組織における局所の炎症反応・骨代謝制御までー2017
- Author(s)
  藤原千春
- Organizer
  第60回日本歯周病学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K17349
[Presentation] CD40-CD40L interaction maintains thymic B cells in the absence of MHC-TCR interaction2016
- Author(s)
  Chiharu Fujihara, Richard J Hodes, Joy Williams
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター (沖縄県宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15H06391
[Presentation] Role of CD40 in immune response and periodontal inflammation2016
- Author(s)
  Chiharu Fujihara
- Organizer
  International symposium Tissue Regeneration and Immunology
- Place of Presentation
  Yonsei University college of Dentistry (Seoul, Korea)
- Year and Date
  2016-02-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06391
[Presentation] FGF-2 inhibits CD40-mediated inflammatory response in periodontal ligament cells2016
- Author(s)
  Chiharu Fujihara, Satoru Yamada, Jirota Kitagaki, Shinya Murakami
- Organizer
  日本歯科保存学会秋季学術大会（第145回）
- Place of Presentation
  長野キッセイ文化ホール (長野県松本市)
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15H06391
[Presentation] CD40-CD40L cognate interaction mediates maintenance of thymic B cells.2015
- Author(s)
  藤原千春、Richard J Hides、村上伸也
- Organizer
  第63回国際歯科研究学会 (JADR) 学術大会
- Place of Presentation
  福岡国際会議場 (福岡県博多市）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-15H06391
[Presentation] Role of CD40 in immune response and periodontal inflammation2015
- Author(s)
  Chiharu Fujihara
- Organizer
  International Symposium 2015 Oral and Craniofacial Development and Diseases
- Place of Presentation
  Osaka University Dental School 大阪府吹田市)
- Year and Date
  2015-12-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06391
[Presentation] 胸腺B細胞維持機構におけるCD40-CD40L相互作用の重要性2015
- Author(s)
  藤原千春、村上伸也、Richard Hodes
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアランド (兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H06391

1. Shinya Murakami (70239490)

# of Collaborated Projects: 10 results

# of Collaborated Products: 30 results
2. 岩山智明 (80757865)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
3. Takedachi Masahide (60452447)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
4. 柏木陽一郎 (20598396)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. YAMASHITA MOTOZO (90524984)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 岡田眞里子 (10342833)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. 三木康史 (10598395)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Yamada Satoru (40359849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. INUBUSHI TOSHIHIRO (30550941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 森崎隆幸 (30174410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 鈴木茂樹 (30549762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 北垣次郎太 (90570292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山口佳則 (20386634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 大倉華雪 (20589684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 北村正博 (10243247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. Canela Andres (90837585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 田中晋 (00367541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山口雅也 (00714536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 黒坂寛 (20509369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 白石優季 (40912457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 内橋俊大 (60757839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 山城隆 (70294428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 飛澤悠葵 (70623768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 森本千晶 (70806801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 石谷太 (40448428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 新保敬史 (70780609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJIHARA CHIHARU 藤原 千春

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

数理モデルに基づく歯周病の病態遷移機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生物時計制御に基づく歯周組織再生効率の向上Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developing prediction of periodontal disease to realize p-dentistryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prediction of periodontal disease progression by a mathematical modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanisms of regeneration of periodontal tissue by mathematical modellingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of the interaction of CD40-CD40L in periodontal tissuePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

FUJIHARA CHIHARU 藤原千春