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SUZUKI AYAKO  鈴木 絢子

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… Alternative Names

Suzuki Ayako  鈴木 絢子

鈴木 絢子  スズキ アヤコ

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Researcher Number 00770348
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院新領域創成科学研究科, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 東京大学, 大学院新領域創成科学研究科, 准教授
2019 – 2020: 東京大学, 大学院新領域創成科学研究科, 特任准教授
2016 – 2017: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Complex systems
Except Principal Investigator
Basic Section 52040:Radiological sciences-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related / Basic Section 50010:Tumor biology-related / Medium-sized Section 50:Oncology and related fields / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 53030:Respiratory medicine-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
Keywords
Principal Investigator
がん / ゲノム / ナノポアシークエンサー / トランスクリプトーム / 空間オミクス解析 / ロングリード技術 / ロングリードシークエンス技術 / 空間トランスクリプトーム解析 / 全長RNA-seq / 転写産物 … More / ネオアンチジェン / がん特異的転写産物 / 非小細胞肺がん / ロングリード / ネオ抗原 / 肺がん / 全長cDNAシークエンス / ロングリードシークエンス / フェージング / がんゲノム … More
Except Principal Investigator
シングルセル解析 / オミクス解析 / 放射線治療 / アブスコパル効果 / deconvolution / VISIUM / ドラッグリポジショニング / プロパゲルマニウム / 乳がん / 大腸癌 / 脱分化 / 線維性癌間質反応 / 簇出 / 低分化胞巣 / 抗腫瘍免疫応答 / 微小残存病変 / MYC / 卵巣がん / リンパ腫 / MYC / TET2 / メラノーマ / クローン性造血 / 病理学 / 遺伝学 / 癌 / 治療標的 / 遺伝子 / ゲノム / 肺がん / シングルセル発現解析 / 肺構成細胞 / LAMP3 / VISTA / 免疫チェックポイント / マクロファージ / 肺癌 / 特発性肺線維症 / エピゲノム / ヒストン修飾 / 精子幹細胞 / 生殖細胞 / 精子形成 / エピジェネティクス / 幹細胞 / 免疫応答 / 免疫応答スイッチ分子 Less
  • Research Projects

    (12 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (24 People)
  •  なぜ高悪性度大腸癌は浸潤先進部で脱分化を起こすのか?-分子生物学的機序の解明

    • Principal Investigator
      梶原 由規
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      National Defense Medical College
  •  VISIUMによる乳がん転移阻害剤プロパゲルマニウムによる免疫能賦活化誘導機構の解明

    • Principal Investigator
      安東 由貴
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  Analysis of network between microenvironmental-cancer cell network in solid cancers

    • Principal Investigator
      Sakata-Yanagimoto Mamiko
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      University of Tsukuba
  •  Elucidation of the molecular basis of MYC-driven cancers and development of therapeutic strategies

    • Principal Investigator
      杉原 英志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Fujita Health University
  •  がん放射線治療後に起きる免疫応答経路の選択に関わる分子の探索

    • Principal Investigator
      善光 純子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      The University of Tokyo
  •  Development of spatial genome and transcriptome analytical methods in local regions of lung cancer tissuesPrincipal Investigator

    • Principal Investigator
      Suzuki Ayako
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      The University of Tokyo
  •  Molecular regulation mechanisms of immune checkpoints by macrophages in IPF-related lung cancer

    • Principal Investigator
      Sekine Ikuo
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      University of Tsukuba
  •  Identification of novel driver genes by whole genome sequencing of early stage lung tumors

    • Principal Investigator
      Kohno Takashi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      National Cancer Center Japan
  •  Research for switch molecules involved in the cancer immune response pathways with cancer radiotherapy.

    • Principal Investigator
      Zenkoh Junko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      The University of Tokyo
  •  Identification of novel neoantigen candidates in cancers by full-length cDNA sequencing using a long read sequencerPrincipal Investigator

    • Principal Investigator
      Suzuki Ayako
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      The University of Tokyo
  •  Analysis of epigenome infertiity mechanism by the state-of-art single cell and ultrtrace histone modification methods

    • Principal Investigator
      OHBO Kazuyuki
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      Yokohama City University
  •  ナノポアシークエンサーによるがん細胞の変異検出およびフェーズ情報解析手法の確立Principal Investigator

    • Principal Investigator
      鈴木 絢子
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      National Cancer Center Japan

All 2024 2023 2022 2021 2020 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Whole-genome sequencing reveals the molecular implications of the stepwise progression of lung adenocarcinoma2023

    • Author(s)
      Haga Y, Sakamoto Y, Kajiya K, Kawai H, Oka M, Motoi N, Shirasawa M, Yotsukura M, Watanabe S, Arai M, Zenkoh J, Shiraishi K, Seki M, Kanai A, Shiraishi Y, Yatabe Y, Matsubara D, Suzuki Y, Noguchi M, Kohno T, Suzuki A.
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 8375-8375

    • DOI

      10.1038/s41467-023-43732-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14469, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H00545, KAKENHI-PROJECT-23K27389, KAKENHI-PROJECT-23K27449
  • [Journal Article] Phasing analysis of lung cancer genomes using a long read sequencer2022

    • Author(s)
      Sakamoto Yoshitaka、Miyake Shuhei、Oka Miho、Kanai Akinori、Kawai Yosuke、Nagasawa Satoi、Shiraishi Yuichi、Tokunaga Katsushi、Kohno Takashi、Seki Masahide、Suzuki Yutaka、Suzuki Ayako
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 3464-3464

    • DOI

      10.1038/s41467-022-31133-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00545, KAKENHI-PROJECT-21H03549, KAKENHI-PROJECT-21J13203, KAKENHI-PROJECT-23K23970
  • [Journal Article] Tsga8 is required for spermatid morphogenesis and male fertility in mice2021

    • Author(s)
      Kobayashi Yuki、Tomizawa Shin-ichi、Ono Michio、Kuroha Kazushige、Minamizawa Keisuke、Natsume Koji、Dizdarevic Selma、Dockal Ivana、Tanaka Hiromitsu、Kawagoe Tatsukata、Seki Masahide、Suzuki Yutaka、Ogonuki Narumi、Inoue Kimiko、Matoba Shogo、Anastassiadis Konstantinos、Mizuki Nobuhisa、Ogura Atsuo、Ohbo Kazuyuki
    • Journal Title

      Development

      Volume: 148 Issue: 8

    • DOI

      10.1242/dev.196212

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07228, KAKENHI-PROJECT-20K09543, KAKENHI-PLANNED-19H05758, KAKENHI-PROJECT-18H02359, KAKENHI-PROJECT-19K23831, KAKENHI-PUBLICLY-20H04934, KAKENHI-PROJECT-19K07250, KAKENHI-PROJECT-19KK0183, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-20H05370, KAKENHI-PROJECT-23K20298
  • [Journal Article] Aberrant splicing isoforms detected by full-length transcriptome sequencing as transcripts of potential neoantigens in non-small cell lung cancer.2021

    • Author(s)
      Oka M, Xu L, Suzuki T, Yoshikawa T, Sakamoto H, Uemura H, Yoshizawa AC, Suzuki Y, Nakatsura T, Ishihama Y, Suzuki A, Seki M
    • Journal Title

      Genome Biol.

      Volume: 22(1):9 Issue: 1 Pages: 1-9

    • DOI

      10.1186/s13059-020-02240-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09297, KAKENHI-PLANNED-17H06306, KAKENHI-PROJECT-19K16108, KAKENHI-PROJECT-19K16792, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K08637, KAKENHI-ORGANIZER-17H06299
  • [Journal Article] Long-read sequencing for non-small-cell lung cancer genomes2020

    • Author(s)
      Sakamoto Y, Xu L, Seki M, Yokoyama TT, Kasahara M, Kashima Y, Ohashi A, Shimada Y, Motoi N, Tsuchihara K, Kobayashi SS, Kohno T, Shiraishi Y, Suzuki A, Suzuki Y.
    • Journal Title

      Genome Res

      Volume: 30 Issue: 9 Pages: 1243-57

    • DOI

      10.1101/gr.261941.120

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07036, KAKENHI-PROJECT-20H00545, KAKENHI-PROJECT-16K21746, KAKENHI-PROJECT-16H06279
  • [Journal Article] DBTSS/DBKERO for integrated analysis of transcriptional regulation2018

    • Author(s)
      Suzuki Ayako、Kawano Shin、Mitsuyama Toutai、Suyama Mikita、Kanai Yae、Shirahige Katsuhiko、Sasaki Hiroyuki、Tokunaga Katsushi、Tsuchihara Katsuya、Sugano Sumio、Nakai Kenta、Suzuki Yutaka
    • Journal Title

      Nucleic Acids Research

      Volume: 46 Issue: (D1) Pages: D229-D238

    • DOI

      10.1093/nar/gkx1001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01582, KAKENHI-PROJECT-15H02369, KAKENHI-PROJECT-16H06279
  • [Journal Article] Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines2018

    • Author(s)
      Sereewattanawoot Sarun、Suzuki Ayako、Seki Masahide、Sakamoto Yoshitaka、Kohno Takashi、Sugano Sumio、Tsuchihara Katsuya、Suzuki Yutaka
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 4926-4926

    • DOI

      10.1038/s41598-018-23342-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01582, KAKENHI-PROJECT-17H04298, KAKENHI-PROJECT-16H06279
  • [Journal Article] Sequencing and phasing cancer mutations in lung cancers using a long-read portable sequencer2017

    • Author(s)
      Suzuki Ayako、Suzuki Mizuto、Mizushima-Sugano Junko、Frith Martin C、Maka?owski Wojciech、Kohno Takashi、Sugano Sumio、Tsuchihara Katsuya、Suzuki Yutaka
    • Journal Title

      DNA Research

      Volume: 24 Issue: 6 Pages: 585-596

    • DOI

      10.1093/dnares/dsx027

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01582, KAKENHI-PROJECT-16H06279
  • [Presentation] 肺オルガノイド空間的トランスクリプトーム解析による次世代創薬プラットフォーム開発 -ニッチオーム介入評価系の新ツールとしての可能性-2024

    • Author(s)
      鈴木敏夫、鈴木 穣、Harry Choi、中川智貴、松原大祐、関根郁夫、永元哲治、池尾 聡、鹿島幸恵、鈴木絢子、山本佑樹
    • Organizer
      第64回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20K08511
  • [Presentation] Spermatogonial chromatin priming for spermiogenic and post-fertilization development2023

    • Author(s)
      富澤 信一、小林 裕貴、Rachel Fellows、鈴木 穣、小倉 淳郎、大保 和之
    • Organizer
      第16回エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-19KK0183
  • [Presentation] ロングリード解析とシングルセル・空間解析の統合に向けて2023

    • Author(s)
      鈴木絢子
    • Organizer
      第45回日本分子生物学会年会(バイオテクノロジーセミナー)
    • Data Source
      KAKENHI-PROJECT-21K15566
  • [Presentation] Role of a novel protease inhibitor for spermatogenesis and immune homeostasis2023

    • Author(s)
      富澤信一, Rachel Fellows, 尾野道男, 黒羽一誠, Ivana Dockal, 南澤恵佑, 鈴木穣, 才津 浩智, 大保和之
    • Organizer
      第128回日本解剖学会総会・全国学術総会
    • Data Source
      KAKENHI-PROJECT-19KK0183
  • [Presentation] 長鎖シークエンス技術を用いた非小細胞肺がんオミクス解析2023

    • Author(s)
      鈴木絢子
    • Organizer
      令和4年度国際がん研究シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00545
  • [Presentation] Research for immune response pathway related molecules following cancer radiation therapy2023

    • Author(s)
      善光純子 鈴木穣 鈴木絢子
    • Organizer
      日本放射線影響学会第66回大会
    • Data Source
      KAKENHI-PROJECT-22K07766
  • [Presentation] ロングリード全ゲノムシークエンスとフェーズ情報解析による肺がんゲノム変異パターンの解明2022

    • Author(s)
      鈴木絢子、坂本祥駿、鈴木穣
    • Organizer
      第81回日本肺癌学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00545
  • [Presentation] Elucidation of diverse transcriptome statuses and their spatial transition in lung adenocarcinoma tissues2021

    • Author(s)
      Suzuki A, Araki T, Suzuki J, Zenkoh J, Suzuki Y.
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K15566
  • [Presentation] 放射線治療と免疫チェックポイント阻害剤を併用した担癌マウスにおける末梢血単核細胞のシングルセルトランスクリプトーム解析2021

    • Author(s)
      善光 純子、鈴木 絢子、松本 孔貴、菅原 裕、鈴木 穣
    • Organizer
      放射線影響学会第64回大会
    • Data Source
      KAKENHI-PROJECT-19K08146
  • [Presentation] ロングリードシークエンス技術を駆使した早期および進行肺がんの比較全ゲノム解析2021

    • Author(s)
      鈴木絢子
    • Organizer
      第62回日本肺癌学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00545
  • [Presentation] Characterization of aberrant transcriptional regulations in lung cancers2018

    • Author(s)
      Ayako Suzuki, Sarun Sereewattanawoot, Yutaka Suzuki, Katsuya Tsuchihara
    • Organizer
      Advances in Genome Biology and Technology (AGBT) 2018 General Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01582
  • [Presentation] Cancer genome phasing of lung adenocarcinoma using long-read sequencing technologies2017

    • Author(s)
      Ayako Suzuki, Sarun Sereewattanawoot, Yutaka Suzuki, Katsuya Tsuchihara
    • Organizer
      The 2017 Advances in Genome Biology and Technology (AGBT) General Meeting
    • Place of Presentation
      フロリダ(米国)
    • Year and Date
      2017-02-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01582
  • [Presentation] Cancer genome phasing for regulatory mutations and allelic transcriptional imbalances using long read sequencing2017

    • Author(s)
      Ayako Suzuki, Sarun Sereewattanawoot, Yutaka Suzuki, Katsuya Tsuchihara
    • Organizer
      第76回 日本癌学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-16H01582
  • [Presentation] Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines2017

    • Author(s)
      Sarun Sereewattanawoot, Ayako Suzuki, Masahide Seki, Takashi Kohno, Sumio Sugano, Katsuya Tsuchihara, Yutaka Suzuki
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PUBLICLY-16H01582
  • [Presentation] ロングリード技術を駆使したregulatory SNVsの転写領域へのフェージング2016

    • Author(s)
      鈴木 絢子
    • Organizer
      第5回生命医薬情報学連合大会IIBMP2016
    • Place of Presentation
      東京国際交流館プラザ平成(東京都江東区)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01582
  • [Presentation] ナノポアシークエンサーによる肺腺癌の変異検出およびフェージング解析2016

    • Author(s)
      鈴木 絢子, 河野 隆志, 土原 一哉, 鈴木 穣
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PUBLICLY-16H01582
  • 1.  鈴木 穣 (40323646)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 2.  Zenkoh Junko (20710148)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  OHBO Kazuyuki (70250751)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  Sekine Ikuo (10508310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  Kohno Takashi (80280783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  Sakata-Yanagimoto Mamiko (80451805)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  坪井 康次 (90188615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  富澤 信一 (00704628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  野口 雅之 (00198582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  鈴木 敏夫 (70771856)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  NGUYEN THI・MINH・YEN (20968010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  杉原 英志 (50464996)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  増田 健太 (30773460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  梶原 由規 (20753023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  上野 秀樹 (90597535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  望月 早月 (80365428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  山寺 勝人 (70993195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  安東 由貴 (50869568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  三森 功士 (50322748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  増田 隆明 (50463493)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  黒羽 一誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  河合 瞳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  元井 紀子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  吉川 聡明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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