Maeda Takahiro 前田高宏

… Alternative Names

Takahiro Maeda 前田高宏

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Researcher Number	00791972
Other IDs	https://orcid.org/0000-0003-4530-6460
Affiliation (Current)	2025: 九州大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 九州大学, 医学研究院, 教授 2017 – 2019: 九州大学, 大学病院, 准教授
Review Section/Research Field	Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Broad Section I / Hematology Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator CRISPR/Cas9 / 急性骨髄性白血病 / 急性リンパ性白血病 / AML / CRISPR / 白血病 / 機能的ジェノミックス / PROTAC / 機能ジェノミクス / BCL2阻害剤 … More / CRSPR/Cas9 / BCL2 / ALL / 合成致死 / p53 / TP53 / 急性白血病 / ゲノム編集 / プレmRNAプロセッシング / 分化誘導療法 / CRISPR/Cas9スクリーニング / PAICS / DCPS … More Except Principal Investigator クローン性造血 / 炎症性腸疾患 / 脊椎関節炎 / 巨細胞性動脈炎 / 加齢性クローナル造血 / 成人スチル病 / 老化 / inflammaging / ベーチェット病 / クローナル造血 / がん微小環境 / システイン / トランスフェリン / PDXマウス / 白血病 / EBV / 劇症型NK白血病 / Epstein Bar virus / アグレッシブNK白血病 / HAVCR2 / 悪性リンパ腫 / 体細胞変異 / 胚細胞変異 / 急性骨髄性白血病 / 体細胞性変異 / ゲノム解析 / 発作性夜間血色素尿症 / 再生不良性貧血 / 治療効果 / 予後 / 脱メチル化薬 / 造血幹細胞移植 / 胚細胞性変異 / DDX41 / 骨髄異形成症候群 / 骨髄不全症候群 Less

難治がんに対する合成致死誘導メカニズムの解明と治療への応用Principal Investigator
- Principal Investigator
  
  前田高宏
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyushu University
自己免疫疾患における加齢性クローナル造血の関連についての検討
- Principal Investigator
  
  小野伸之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyushu University
Development of novel therapeutic strategies for therapy-refractory leukemiaPrincipal Investigator
- Principal Investigator
  
  前田高宏
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Kyushu University
Identifying molecular mechanisms underlying treatment-refractory leukemia and their targeting strategiesPrincipal Investigator
- Principal Investigator
  
  前田高宏
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyushu University
Analysis of tumor microenvironment in aggressive NK leukemia
- Principal Investigator
  
  Kotani Ai
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tokai University
Clinical application of germline and somatic mutations in bone marrow failure syndromes.
- Principal Investigator
  
  Makishima Hideki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Shinshu University
  Kyoto University
Identification of novel targets for leukemia therapy using genome-wide CRISPR/Cas9 screensPrincipal Investigator
- Principal Investigator
  
  Takahiro Maeda
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University

All 2023 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] Targeting a mitochondrial E3 ubiquitin ligase complex to overcome AML cell-intrinsic Venetoclax resistance2023
- Author(s)
  Nakao Fumihiko、Setoguchi Kiyoko、Semba Yuichiro、Yamauchi Takuji、Nogami Jumpei、Sasaki Kensuke、Imanaga Hiroshi、Terasaki Tatsuya、Miyazaki Manaka、Hirabayashi Shigeki、Miyawaki Kohta、Kikushige Yoshikane、Masuda Takeshi、Akashi Koichi、Maeda Takahiro
- Journal Title
  
  Leukemia
  
  Volume: - Issue: 5 Pages: 1028-1038
- DOI
  10.1038/s41375-023-01879-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16323, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-23K07816, KAKENHI-PROJECT-20H05699, KAKENHI-PROJECT-21H04827
[Journal Article] CELMoD for ALL: an exciting prospect2023
- Author(s)
  Maeda Takahiro
- Journal Title
  
  Blood
  
  Volume: 142 Issue: 7 Pages: 614-615
- DOI
  10.1182/blood.2023020923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05699
[Journal Article] MOZ/ENL complex is a recruiting factor of leukemic AF10 fusion proteins2023
- Author(s)
  Komata Yosuke、Kanai Akinori、Maeda Takahiro、Inaba Toshiya、Yokoyama Akihiko
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-17
- DOI
  10.1038/s41467-023-37712-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0119, KAKENHI-PROJECT-20H05699, KAKENHI-PROJECT-21H02948, KAKENHI-PROJECT-23K24368
[Journal Article] The initial assessment of expert panel performance in core hospitals for cancer genomic medicine in Japan2021
- Author(s)
  Sunami K, Naito Y, Aimono E, Amano T, Ennishi D, Kage H, Kanai M, Komine K, Koyama T, Maeda T, Morita S, Sakai D, Kohsaka S, Tsuchihara K, Yoshino T
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 26 Issue: 3 Pages: 443-449
- DOI
  10.1007/s10147-020-01844-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-20H05699
[Journal Article] Outcome predictors after retransplantation in relapsed acute lymphoblastic leukemia: a multicenter, retrospective study2020
- Author(s)
  Mori Yasuo、Fukuoka Blood and Marrow Transplantation Group、Sasaki Kensuke、Ito Yoshikiyo、Kuriyama Takuro、Ueno Toshiyuki、Kadowaki Masanori、Aoki Takatoshi、Sugio Takeshi、Yoshimoto Goichi、Kato Koji、Maeda Takahiro、Nagafuji Koji、Akashi Koichi、Miyamoto Toshihiro
- Journal Title
  
  Annals of Hematology
  
  Volume: 100 Issue: 1 Pages: 197-208
- DOI
  10.1007/s00277-020-04310-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17403, KAKENHI-PROJECT-20J00897, KAKENHI-PROJECT-21H02951, KAKENHI-PROJECT-20H05699
[Journal Article] Beneficial tyrosine kinase inhibitor therapy in a patient with relapsed BCR-ABL1-like acute lymphoblastic leukemia with CCDC88C-PDGFRB fusion2020
- Author(s)
  Oya Shuki、Morishige Satoshi、Ozawa Hidetoshi、Sasaki Kensuke、Semba Yuichiro、Yamasaki Yoshitaka、Nakamura Takayuki、Aoyama Kazutoshi、Seki Ritsuko、Mouri Fumihiko、Osaki Koichi、Miyamoto Toshihiro、Maeda Takahiro、Nagafuji Koji
- Journal Title
  
  International Journal of Hematology
  
  Volume: 113 Issue: 2 Pages: 285-289
- DOI
  10.1007/s12185-020-03006-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H05699
[Journal Article] Aromatase is a novel neo-substrate of cereblon responsible for immunomodulatory drugs-induced thrombocytopenia. Tochigi T, Miyamoto T, Hatakeyama K, Sakoda T, Ishihara D, Irifune H, Shima T, Kato K, Maeda T, Ito T, Handa H, Akashi K, Kikushige Y.2020
- Author(s)
  Tochigi T, Miyamoto T, Hatakeyama K, Sakoda T, Ishihara D, Irifune H, Shima T, Kato K, Maeda T, Ito T, Handa H, Akashi K, Kikushige Y.
- Journal Title
  
  Blood.
  
  Volume: - Issue: 24 Pages: 2146-2158
- DOI
  10.1182/blood.2019003749
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-18K19565, KAKENHI-PROJECT-20K21617, KAKENHI-PROJECT-18K08362, KAKENHI-PROJECT-20H05699
[Journal Article] Establishment of a human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells2020
- Author(s)
  Jinnouchi Fumiaki、Yamauchi Takuji、Yurino Ayano、Nunomura Takuya、Nakano Michitaka、Iwamoto Chika、Obara Teppei、Miyawaki Kohta、Kikushige Yoshikane、Kato Koji、Maeda Takahiro、Miyamoto Toshihiro、Baba Eishi、Akashi Koichi、Takenaka Katsuto
- Journal Title
  
  Blood
  
  Volume: - Issue: 19 Pages: 1661-1672
- DOI
  10.1182/blood.2019002194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16366, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-18H02840, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-18K19565, KAKENHI-PROJECT-19K08818, KAKENHI-PROJECT-18K08362, KAKENHI-PROJECT-20H05699
[Journal Article] Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis2019
- Author(s)
  33.Sher F, Hossain M, Seruggia D, Schoonenberg V.A.C., Yao Q, Cifani P, Dassama L.M.K., Cole MA, Ren C, Vinjamur DS, Macias-Trevino C, Luk K, McGuckin C, Schupp PG, Canver M.C., Kurita R, Nakamura Y, Fujiwara Y, Wolfe SA, Pinello L, Maeda T, Kentsis A, Orkin SH, Bauer DE.
- Journal Title
  
  Nature Genetics
  
  Volume: 51 Issue: 7 Pages: 1149-1159
- DOI
  10.1038/s41588-019-0453-4
- Data Source
  KAKENHI-PROJECT-17H01567
[Journal Article] DrugThatGene: integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens2018
- Author(s)
  Canver Matthew C、Bauer Daniel E、Maeda Takahiro、Pinello Luca
- Journal Title
  
  Bioinformatics
  
  Volume: 5 Issue: 11 Pages: 00-00
- DOI
  10.1093/bioinformatics/bty913
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Journal Article] Microenvironmental immune cell signatures dictate clinical outcomes for PTCL-NOS.2018
- Author(s)
  Sugio T, Miyawaki K, Kato K, Sasaki K, Yamada K, Iqbal J, Miyamoto T, Ohshima K, Maeda T, Miyoshi H, Akashi K.
- Journal Title
  
  Blood Advances
  
  Volume: 2 Issue: 17 Pages: 2242-2252
- DOI
  10.1182/bloodadvances.2018018754
- NAID
  40021890654
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19565, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-17H01567, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-16K09875
[Journal Article] Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.2018
- Author(s)
  Yamauchi T, et al.
- Journal Title
  
  Cancer Cell.
  
  Volume: 33 Issue: 3 Pages: 386-400
- DOI
  10.1016/j.ccell.2018.01.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-17H01567, KAKENHI-PROJECT-17H04208, KAKENHI-PROJECT-15J10130, KAKENHI-PROJECT-17K15042
[Journal Article] Molecular pathogenesis of disease progression in MLL-rearranged AML.2018
- Author(s)
  Kotani S, Yoda A, Kon A, Kataoka K, Ochi Y, Shiozawa Y, Hirsch C, Takeda J, Ueno H, Yoshizato T, Yoshida K, Nakagawa MM, Nannya Y, Kakiuchi N, Yamauchi T, Aoki K, Shiraishi Y, Miyano S, Maeda T, Maciejewski JP, Takaori-Kondo A, Ogawa S, Makishima H.
- Journal Title
  
  Leukemia
  
  Volume: 33 Issue: 3 Pages: 612-624
- DOI
  10.1038/s41375-018-0253-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16084, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-17H01567, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-17H04990, KAKENHI-PROJECT-17J05245, KAKENHI-PROJECT-17K19595, KAKENHI-PROJECT-19H01053
[Journal Article] CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis2018
- Author(s)
  Schoonenberg Vivien A. C.、Cole Mitchel A.、Yao Qiuming、Macias-Trevino Claudio、Sher Falak、Schupp Patrick G.、Canver Matthew C.、Maeda Takahiro、Pinello Luca、Bauer Daniel E.
- Journal Title
  
  Genome Biology
  
  Volume: 19 Issue: 1 Pages: 00-00
- DOI
  10.1186/s13059-018-1563-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Journal Article] Identification of unipotent megakaryocyte progenitors in human hematopoiesis.2017
- Author(s)
  K. Miyawaki. Iwasaki, T. Jiromaru, H. Kusumoto, A. Yurino, T. Sugio, Y. Uehara, J. Odawara, S. Daitoku, Y. Kunisaki, Y. Mori, Y. Arinobu, H. Tsuzuki, Y. Kikushige, T. Iino, K. Kato, K. Takenaka, T. Miyamoto, T. Maeda, *K. Akashi
- Journal Title
  
  Blood
  
  Volume: 印刷中 Issue: 25 Pages: 3332-3343
- DOI
  10.1182/blood-2016-09-741611
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-15H04859, KAKENHI-PROJECT-15K15364, KAKENHI-PROJECT-16K09897, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-17H01567, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-16H06250, KAKENHI-PROJECT-15K15365, KAKENHI-PROJECT-16K19578
[Patent] Identification of 131 Acute Myeloid Leukemia (AML) essential genes2018
- Inventor(s)
  Maeda T, Yamauchi T, MaedaM
- Industrial Property Rights Holder
  Maeda T, Yamauchi T, MaedaM
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17H01567
[Patent] DCPS as a target for Acute Myeloid Leukemia2017
- Inventor(s)
  Maeda T, Yamauchi T, MaedaM
- Industrial Property Rights Holder
  Maeda T, Yamauchi T, MaedaM
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] Identifying novel combination therapies for B-ALL harboring the IgH::CRLF2 rearrangement using functional genomics tools2023
- Author(s)
  Takahiro Maeda
- Organizer
  3rd Translational Research Conference Acute Lymphoblastic Leukaemia.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05699
[Presentation] Identifying novel targets for AML therapy using functional genomic tools.2023
- Author(s)
  Takahiro Maeda
- Organizer
  BMT/HM Grand Rounds, Dana-Farber Cancer Institute.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05699
[Presentation] Identifying novel targets for AML therapy using functional genomic tools.2023
- Author(s)
  Takahiro Maeda
- Organizer
  Japanese Society of Medical Oncology Annual meeting.
- Invited
- Data Source
  KAKENHI-PROJECT-20H05699
[Presentation] The XPO7/NPAT axis as a potential therapeutic target for TP53-mutated AML.2023
- Author(s)
  Takahiro Maeda
- Organizer
  FASEB Hematologic Malignancies Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05699
[Presentation] Multifaceted roles of the transcription factor ZBTB7A in normal and malignant hematopoiesis2023
- Author(s)
  Takahiro Maeda
- Organizer
  Tsuruoka Conference 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05699
[Presentation] Harnessing functional genomics to uncover potential targets for AML therapy.2023
- Author(s)
  Takahiro Maeda
- Organizer
  Japanese Cancer Society annual meeting
- Invited
- Data Source
  KAKENHI-PROJECT-20H05699
[Presentation] CRISPR/Cas9 遺伝子改変技術を用いた白血病治療標的分子の同定2020
- Author(s)
  前田高宏
- Organizer
  鶴岡カンファレンス 2020
- Invited
- Data Source
  KAKENHI-PROJECT-20H05699
[Presentation] 白血病のクローン多様性克服に向けて2020
- Author(s)
  前田高宏
- Organizer
  日本造血幹細胞移植学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H05699
[Presentation] Genome-wide CRISPR screen identifies PAICS, and enzyme involved in de novo purine synthesis, as a potential target for AML therapy.2019
- Author(s)
  Yamauchi T, Miyawaki K, Semba Y, Nakao F, Nogami J, Sugio T, Sasaki K, Canver MC, Osborne S, Pinello L, Taylor D, Bauer DR, Akashi K, Maeda T
- Organizer
  FASEB: The Hematologic Malignancies Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] CRISPR-Cas9 screen identifies XPO7 as a potential therapeutic target for TP53-mutated AML.2019
- Author(s)
  42.SembaY, Yamauchi T, Nakao F, Nogami J, Canver MC, Pinello L, Bauer DE, Akashi K, Maeda T.
- Organizer
  61th American Society of Hematology annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] CRISPR-Cas9 screen identifies Me2, a mitochondrial malic enzyme, as a molecule relevant for MCL1 inhibitor resistance2019
- Author(s)
  Nakao F, Yamauchi T, SembaY, Nogami J, Akashi K and Maeda T.
- Organizer
  FASEB: The Hematologic Malignancies Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] CRISPR-Cas9 screen identifies Me2, a mitochondrial malic enzyme, as a molecule relevant for MCL1 inhibitor resistance in AML.2019
- Author(s)
  Nakao F, Yamauchi T, SembaY, Nogami J, Akashi K and Maeda T.
- Organizer
  61th American Society of Hematology annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] CRISPR-Cas9 screen identifies XPO7 as a novel therapeutic target for TP53-mutated AML2019
- Author(s)
  SembaY, Yamauchi T, Nakao F, Nogami J, Canver MC, Pinello L, Bauer DE, Akashi K, Maeda T.
- Organizer
  Society of Hematologic Oncology (SOHO) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] Genome-wide CRISPR screen identifies PAICS, an enzyme involved in de novo purine synthesis, as a potential target for AML therapy2019
- Author(s)
  amauchi T, Miyawaki K, Semba Y, Nakao F, Nogami J, Sugio T, Sasaki K, Canver MC, Osborne S, Pinello L, Taylor D, Bauer DR, Akashi K, Maeda T.
- Organizer
  Society of Hematologic Oncology (SOHO) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] CRISPR-Cas9 screen identifies XPO7 as a novel therapeutic target for TP53-mutated AML2019
- Author(s)
  34.SembaY, Yamauchi T, Nakao F, Nogami J, Canver MC, Pinello L, Bauer DE, Akashi K, Maeda T.
- Organizer
  FASEB: The Hematologic Malignancies Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] PAICS, a de novo purine synthetic enzyme, is a novel target for AML therapy.2019
- Author(s)
  Yamauchi T, Miyawaki K, Semba Y, Nakao F, Nogami J, Sugio T, Sasaki K, Canver MC, Osborne S, Pinello L, Taylor D, Bauer DR, Akashi K, Maeda T.
- Organizer
  61th American Society of Hematology annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] PAICS inhibition is a potential therapeutic strategy for MYC-positive DLBCL2019
- Author(s)
  Miyawaki K, Yamauchi T, SugioT, Sasaki K, Miyoshi H, Osborne S, Taylor D, Ohshima K, Kato K, Maeda T, Akashi K
- Organizer
  61th American Society of Hematology annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] PAICS inhibition is a potential therapeutic strategy for MYC-positive aggressive DLBCL2019
- Author(s)
  Miyawaki K, Yamauchi T, SugioT, Sasaki K, Miyoshi H, Osborne S, Taylor D, Ohshima K, Kato K, Maeda T, Akashi K
- Organizer
  Society of Hematologic Oncology (SOHO) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] Leukemia-specific dependence on a nuclear pre-mRNA processing pathway regulated by the DCPS decapping enzyme. Novel insights into nuclear events in cancer.2018
- Author(s)
  Takahiro Maeda
- Organizer
  Novel insights into nuclear events in cancer, Singapore
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01567
[Presentation] Identifying novel targets for leukemia therapy using the CRISPR/Cas9 gene-editing tool2018
- Author(s)
  Takahiro Maeda
- Organizer
  Japanese Cancer Association Annual Meeting, Osaka
- Invited
- Data Source
  KAKENHI-PROJECT-17H01567

1. 山内拓司 (20796213)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. 野上順平 (60801751)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 増田豪 (70383940)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 仙波雄一郎 (90816787)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. Makishima Hideki (40402127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Kotani Ai (00517477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 菊繁吉謙 (40619706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 村松秀城 (00572570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宮崎泰司 (40304943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 半田寛 (90282409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小野伸之 (00336025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 江里口芳裕 (70552016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KATO Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. YOSHIDA Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 赤司浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 宮脇恒太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 杉尾健志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 平林茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 宮本敏浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 高阪真路

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 岩本千佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 昆彩奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 小俣洋介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 金井昭教

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maeda Takahiro 前田 高宏

Takahiro Maeda 前田 高宏

Research Projects

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難治がんに対する合成致死誘導メカニズムの解明と治療への応用Principal Investigator

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自己免疫疾患における加齢性クローナル造血の関連についての検討

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Development of novel therapeutic strategies for therapy-refractory leukemiaPrincipal Investigator

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Identifying molecular mechanisms underlying treatment-refractory leukemia and their targeting strategiesPrincipal Investigator

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Analysis of tumor microenvironment in aggressive NK leukemia

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Clinical application of germline and somatic mutations in bone marrow failure syndromes.

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Identification of novel targets for leukemia therapy using genome-wide CRISPR/Cas9 screensPrincipal Investigator

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[Journal Article] Targeting a mitochondrial E3 ubiquitin ligase complex to overcome AML cell-intrinsic Venetoclax resistance2023

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[Journal Article] CELMoD for ALL: an exciting prospect2023

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[Journal Article] MOZ/ENL complex is a recruiting factor of leukemic AF10 fusion proteins2023

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[Journal Article] The initial assessment of expert panel performance in core hospitals for cancer genomic medicine in Japan2021

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[Journal Article] Outcome predictors after retransplantation in relapsed acute lymphoblastic leukemia: a multicenter, retrospective study2020

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[Journal Article] Beneficial tyrosine kinase inhibitor therapy in a patient with relapsed BCR-ABL1-like acute lymphoblastic leukemia with CCDC88C-PDGFRB fusion2020

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[Journal Article] Aromatase is a novel neo-substrate of cereblon responsible for immunomodulatory drugs-induced thrombocytopenia. Tochigi T, Miyamoto T, Hatakeyama K, Sakoda T, Ishihara D, Irifune H, Shima T, Kato K, Maeda T, Ito T, Handa H, Akashi K, Kikushige Y.2020

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Maeda Takahiro 前田高宏

Takahiro Maeda 前田高宏