Kohsaka Shinji 高阪真路

… Alternative Names

Researcher Number	00627119
Other IDs
Affiliation (Current)	2021: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
Affiliation (based on the past Project Information) *help	2021: 国立研究開発法人国立がん研究センター, その他部局等, その他 2020: 国立研究開発法人国立がん研究センター, 研究所, ユニット長 2018 – 2020: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員 2016 – 2017: 東京大学, 大学院医学系研究科(医学部), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Orthopaedic surgery / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 56020:Orthopedics-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 肉腫 / 融合遺伝子 / バイオマテリアル / 機能解析 Except Principal Investigator 骨軟部腫瘍 / 融合遺伝子 / 骨軟部肉腫 / チロシンキナーゼ / 肉腫 / ゲノム解析 … More

分子標的治療耐性化メカニズムの網羅的探索Principal InvestigatorOngoing
- Principal Investigator
  
  高阪真路
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Cancer Center Japan
Reprogramming of cancer stem cells by high-function hydrogels creates basis to establish novel cancer therapyOngoing
- Principal Investigator
  
  田中伸哉
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
がんクリニカルシークエンス解析に基づいた「骨軟部腫瘍分子標的」の作用機序解明Ongoing
- Principal Investigator
  
  末原義之
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
骨軟部腫瘍の「小胞体ストレス」機能解析に基づいた新規治療法開発Ongoing
- Principal Investigator
  
  末原義之
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Juntendo University
肉腫融合遺伝子による発がんメカニズムの統合的探索Principal InvestigatorOngoing
- Principal Investigator
  
  高阪真路
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cancer Center Japan
Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcomaOngoing
- Principal Investigator
  
  松田浩一
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Screening for alternative transcription initiation of tyrosine kinase genes in bone and soft tissue tumors
- Principal Investigator
  
  Suehara Yoshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University

All 2019 2018

All Presentation Book

[Book] Precision Medicine　2019年2月号　がんクリニカルシークエンス検査の開発と臨床応用2019
- Author(s)
  高阪真路, 辰野健二, 織田克利
- Total Pages
  102
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] 病理と臨床 2019年10月号シングルセル解析遺伝子解析2019
- Author(s)
  高阪真路
- Total Pages
  112
- Publisher
  文光堂
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] BIO Clinica 2019年 8月臨時増刊号 VUS解釈のためのハイスループット機能解析法2019
- Author(s)
  高阪真路
- Total Pages
  100
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] 医学のあゆみがん研究10か年戦略の成果と課題プレシジョンメディシンの実現に向けた意義不明変異の解釈2019
- Author(s)
  高阪真路
- Total Pages
  272
- Publisher
  医歯薬出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] 実験医学増刊 Vol.36 No.15　動き始めた　がんゲノム医療2018
- Author(s)
  高阪真路
- Total Pages
  243
- Publisher
  羊土社
- ISBN
  9784758103732
- Data Source
  KAKENHI-PROJECT-18H02677
[Book] 特集　がんゲノム医療・Precision Medicineの展開と諸問題2018
- Author(s)
  高阪真路, 辰野健二, 織田克利
- Total Pages
  132
- Publisher
  科学評論社
- ISBN
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] シングルセル解析のがんゲノム医療への応用2019
- Author(s)
  高阪真路
- Organizer
  第16回日本病理学会カンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 軟部肉腫pazopanib著効例の特徴的遺伝子増幅変化.2019
- Author(s)
  末原義之, 高阪真路, 山口茂夫, 林大久生, 栗原大聖, 赤池慶祐, 金子和夫, 齋藤剛, 間野博行, 加藤俊介.
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 軟部肉腫のROS1融合遺伝子同定とその機能解析.2019
- Author(s)
  末原義之, 高阪真路, 林大久生, 赤池慶祐, 佐藤信吾, 小林英介, 金栄智, 大久保武人, 金子和夫, 間野博行, 齋藤剛.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Nanostringを用いたinflammatory myofibroblastic tumor/Inflammatory pseudotumorにおける融合遺伝子解析.2019
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 林大久生, 長谷川延彦, 高阪真路, 八尾隆史, 金子和夫, 齋藤剛.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 軟部肉腫pazopanib著効例の12q13-14遺伝子増幅変化.2019
- Author(s)
  末原義之, 高阪真路, 山口茂夫, 林大久生, 栗原大聖, 赤池慶祐, 金子和夫, 齋藤剛, 間野博行, 加藤俊介.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] がん遺伝子における意義不明バリアントのハイスループット機能解析法2019
- Author(s)
  高阪真路, 長野匡晃, 上野敏秀, 間野博行
- Organizer
  第17回日本臨床学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] Application of a High-throughput Functional Evaluation of Variants of Unknown Significance to Personalized Medicine2019
- Author(s)
  高阪真路
- Organizer
  第38回札幌国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] シンポジウム：骨・軟部腫瘍のゲノム医療とカウンセリング_軟部肉腫のTyrosine kinase融合遺伝子・遺伝子変異体の探索2019
- Author(s)
  末原義之, 高阪真路, 栗崎愛子, 林大久生, 赤池慶祐, 佐藤信吾, 小林英介, 金子和夫, 間野博行, 齋藤剛.
- Organizer
  52回日本整形外科学会骨・軟部腫瘍学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] がん研究からがんゲノム医療への応用2019
- Author(s)
  高阪真路
- Organizer
  2019年度第1回教育研修・講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] EGFR遺伝子exon 20挿入変異に対するハイスループット機能解析2019
- Author(s)
  廣瀬毅, 高阪真路, 池上政周, 間野博行
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] Nanostringを用いたIMT/IPTにおけるチロシンキナーゼ融合遺伝子の解析2019
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 長谷川延彦, 林大久生, 高阪真路, 高木辰哉, 八尾隆史, 金子和夫, 斎藤剛.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] ハイスループット遺伝子機能解析法のがんゲノム医療への応用2019
- Author(s)
  高阪真路
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 骨・軟部肉腫における血中循環腫瘍細胞の同定.2019
- Author(s)
  長谷川延彦, 高阪真路, 末原義之, 赤池慶祐, 大久保武人, 高木辰哉, 林大久生, 齋藤剛, 金子和夫, 間野博行.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨軟部肉腫におけるマイクロ流路チップ・セルソーターを使用した循環腫瘍細胞の同定と次世代シーケンシング2019
- Author(s)
  長谷川延彦, 高阪真路, 中村育子, 末原義之, 高木辰哉, 林大久生, 斎藤剛, 金子和夫, 間野博行.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] がん個別化医療の実現に向けた戦略的研究開発2019
- Author(s)
  高阪真路
- Organizer
  第237回呼吸器学会関東地方会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がんゲノム医療の実現にむけたがん遺伝子ハイスループット機能解析法の構築2019
- Author(s)
  高阪真路
- Organizer
  第30回日本医学会総会
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] ゲノム医療におけるリキッドバイオプシーの有用性2019
- Author(s)
  高阪真路, 間野博行
- Organizer
  第108回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がんゲノム医療のためのハイスループット機能解析法の確立2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第107回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] ハイスループット機能解析法のがんゲノム医療への応用2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 肺がん関連遺伝子変異のハイスループット機能解析2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第22回がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] がん遺伝子ハイスループット機能解析によるがん生物学の統合的理解2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第41回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] NGSのゲノム解析レポートの読み方2018
- Author(s)
  高阪真路
- Organizer
  第107回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677
[Presentation] 意義不明変異陽性がんに対する分子標的治療2018
- Author(s)
  高阪真路, 長野匡晃, 間野博行
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02677

1. Suehara Yoshiyuki (70509405)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. 小林英介 (40365292)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 林大久生 (70569128)

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# of Collaborated Products: 8 results
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5. 北野滋久 (60402682)

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6. 松田浩一 (90401257)

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51. ENDO Makoto

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53. MUKAIHARA Kenta

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55. TANABE Yu

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56. ISHII Midori

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Kohsaka Shinji 高阪 真路

高阪 真路 コウサカ シンジ

Research Projects

Research Products

Co-Researchers

分子標的治療耐性化メカニズムの網羅的探索Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reprogramming of cancer stem cells by high-function hydrogels creates basis to establish novel cancer therapyOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がんクリニカルシークエンス解析に基づいた「骨軟部腫瘍分子標的」の作用機序解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨軟部腫瘍の「小胞体ストレス」機能解析に基づいた新規治療法開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肉腫融合遺伝子による発がんメカニズムの統合的探索Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcomaOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening for alternative transcription initiation of tyrosine kinase genes in bone and soft tissue tumors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Precision Medicine 2019年2月号 がんクリニカルシークエンス検査の開発と臨床応用2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 病理と臨床 2019年10月号 シングルセル解析遺伝子解析2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] BIO Clinica 2019年 8月臨時増刊号 VUS解釈のためのハイスループット機能解析法2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 医学のあゆみ がん研究10か年戦略の成果と課題 プレシジョンメディシンの実現に向けた意義不明変異の解釈2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 実験医学増刊 Vol.36 No.15 動き始めた がんゲノム医療2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 特集 がんゲノム医療・Precision Medicineの展開と諸問題2018

Author(s)

Total Pages

Kohsaka Shinji 高阪真路

高阪真路コウサカシンジ

[Book] Precision Medicine　2019年2月号　がんクリニカルシークエンス検査の開発と臨床応用2019

[Book] 病理と臨床 2019年10月号シングルセル解析遺伝子解析2019

[Book] 医学のあゆみがん研究10か年戦略の成果と課題プレシジョンメディシンの実現に向けた意義不明変異の解釈2019

[Book] 実験医学増刊 Vol.36 No.15　動き始めた　がんゲノム医療2018

[Book] 特集　がんゲノム医療・Precision Medicineの展開と諸問題2018