Yamazaki Reiji 山崎礼二

Researcher Number	00870718
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 自治医科大学, 医学部, 講師 2022 – 2023: 自治医科大学, 医学部, 講師 2020 – 2021: 自治医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 59010:Rehabilitation science-related / Basic Section 48010:Anatomy-related / 0704:Neuroscience, brain sciences, and related fields Except Principal Investigator Basic Section 58040:Forensics medicine-related
Keywords	Principal Investigator 脱髄 / ミエリン / オリゴデンドロサイト / mTOR / 再ミエリン化 / クレアチン / 多発性硬化症 Except Principal Investigator 老化 / 加齢 / 血管リモデリング / 血管線維化 / 脳細動脈硬化 / 脳血管周囲マクロファージ

脳梗塞におけるDDR1シグナルとリハビリを応用した新たな治療戦略Principal Investigator
- Principal Investigator
  
  山崎礼二
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Jichi Medical University
Therapeutic applications for demyelinating diseases via mTOR signallingPrincipal Investigator
- Principal Investigator
  
  山崎礼二
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Jichi Medical University
Elucidation of the role of perivascular macrophages in stroke using animal models for disease and autopsy brains
- Principal Investigator
  
  稲垣健志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Jichi Medical University
Novel therapies for multiple sclerosis by targeting creatine metabolism in the brainPrincipal Investigator
- Principal Investigator
  
  Yamazaki Reiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0704:Neuroscience, brain sciences, and related fields
- Research Institution
  Jichi Medical University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] The Mouse Model of Internal Capsule Demyelination: A Novel Tool for Investigating Motor Functional Changes Caused by Demyelination and for Evaluating Drugs That Promote Remyelination2024
- Author(s)
  Yamazaki Reiji、Ohno Nobuhiko
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 57 Issue: 1 Pages: 1-5
- DOI
  10.1267/ahc.24-00005
- ISSN
  0044-5991, 1347-5800
- Year and Date
  2024-02-29
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14432, KAKENHI-PLANNED-21H05241
[Journal Article] Pharmacological treatment promoting remyelination enhances motor function after internal capsule demyelination in mice2023
- Author(s)
  Yamazaki Reiji、Osanai Yasuyuki、Kouki Tom、Huang Jeffrey K.、Ohno Nobuhiko
- Journal Title
  
  Neurochemistry International
  
  Volume: 164 Pages: 105505-105505
- DOI
  10.1016/j.neuint.2023.105505
- Data Source
  KAKENHI-PROJECT-20K22690
[Journal Article] Correlative light and electron microscopic observation of calcium phosphate particles in a mouse kidney formed under a high-phosphate diet2023
- Author(s)
  Battulga Batpurev、Shiizaki Kazuhiro、Miura Yutaka、Osanai Yasuyuki、Yamazaki Reiji、Shinohara Yoshiaki、Kubota Yoshiyuki、Hara Toru、Kuro-o Makoto、Ohno Nobuhiko
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 852-860
- DOI
  10.1038/s41598-023-28103-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03295, KAKENHI-PROJECT-20K21506, KAKENHI-PROJECT-20K22690, KAKENHI-PROJECT-19H03336
[Journal Article] Dark Rearing in the Visual Critical Period Causes Structural Changes in Myelinated Axons in the Adult Mouse Visual Pathway2022
- Author(s)
  Osanai Yasuyuki、Battulga Batpurev、Yamazaki Reiji、Kouki Tom、Yatabe Megumi、Mizukami Hiroaki、Kobayashi Kenta、Shinohara Yoshiaki、Yoshimura Yumiko、Ohno Nobuhiko
- Journal Title
  
  Neurochemical Research
  
  Volume: 47 Issue: 9 Pages: 2815-2825
- DOI
  10.1007/s11064-022-03689-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15197, KAKENHI-PLANNED-21H05241, KAKENHI-PROJECT-20K22690, KAKENHI-ORGANIZER-21H05238
[Journal Article] Heterogeneity and regulation of oligodendrocyte morphology2022
- Author(s)
  Osanai Yasuyuki、Yamazaki Reiji、Shinohara Yoshiaki、Ohno Nobuhiko
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 1-13
- DOI
  10.3389/fcell.2022.1030486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15197, KAKENHI-PLANNED-21H05241, KAKENHI-PROJECT-20H03295, KAKENHI-PROJECT-20K22690
[Journal Article] Macroscopic detection of demyelinated lesions in mouse PNS with neutral red dye2021
- Author(s)
  Yamazaki Reiji、Osanai Yasuyuki、Kouki Tom、Shinohara Yoshiaki、Huang Jeffrey K.、Ohno Nobuhiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-021-96395-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22690, KAKENHI-PROJECT-20H03295
[Journal Article] Perivascular macrophages produce type I collagen around cerebral small vessels under prolonged hypertension in rats2021
- Author(s)
  Inagaki Takeshi、Fujiwara Ken、Shinohara Yoshiaki、Azuma Morio、Yamazaki Reiji、Mashima Kiyomi、Sakamoto Atsushi、Yashiro Takashi、Ohno Nobuhiko
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: Published online Issue: 4 Pages: 1-10
- DOI
  10.1007/s00418-020-01948-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22690, KAKENHI-PROJECT-17H02221, KAKENHI-PROJECT-17K08517, KAKENHI-PROJECT-20K15834, KAKENHI-PROJECT-20H03295
[Presentation] 白質障害領域に分泌される I 型コラーゲンは白質の再生を阻害する2024
- Author(s)
  山崎礼二, 東森生, 長内康幸, 幸喜富, 大野伸彦
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-23K14432
[Presentation] 白質障害領域に沈着する I 型コラーゲンは再ミエリン化を阻害する2024
- Author(s)
  山崎礼二, 東森生, 長内康幸, 幸喜富, 大野伸彦
- Organizer
  第8回日本ミエリン研究会
- Data Source
  KAKENHI-PROJECT-23K14432
[Presentation] 新たな病変標識法と病態モデルを応用した脱髄研究2023
- Author(s)
  山崎礼二, 大野伸彦
- Organizer
  第64回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-23K14432
[Presentation] The morphological analysis of individual oligodendrocytes in aged mice by serial block face-scanning electron microscopy2023
- Author(s)
  Sasikarn Looprasertkul, Reiji Yamazaki, Yasuyuki Osanai, Megumi Yatabe, Kouki Tom, Kimiyo Yagai, Batpurev Battulga, Nobuhiko Ohno
- Organizer
  第66回日本顕微鏡学会シンポジウム
- Data Source
  KAKENHI-PROJECT-23K14432
[Presentation] Clemastine improves motor dysfunction caused by internal capsule demyelination in mice.2023
- Author(s)
  山崎　礼二，長内　康幸，幸喜　富，大野　伸彦
- Organizer
  第128回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] 脳細動脈硬化における血管線維化と脳血管周囲マクロファージの役割2023
- Author(s)
  稲垣健志, 山崎礼二, 長内康幸, 東森生, 鈴木秀人, 大野伸彦
- Organizer
  第55回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-23K09773
[Presentation] 脳虚血に伴う白質再生障害機構の解明2023
- Author(s)
  山崎　礼二，東　森生、長内　康幸，幸喜　富，大野　伸彦
- Organizer
  第７回日本ミエリン研究会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] 内包脱髄モデルマウスによる再髄鞘化促進薬の新たな評価法2022
- Author(s)
  山崎　礼二，長内　康幸，幸喜　富，篠原　良章，大野　伸彦
- Organizer
  第65回日本神経化学会，第45回日本神経科学会，第32回日本神経回路学会合同大会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] クレマスチンはマウスの内包脱髄に伴う運動機能障害を改善する。2022
- Author(s)
  山崎　礼二，長内　康幸，幸喜　富，大野　伸彦
- Organizer
  日本解剖学会第110回関東支部学術集会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] 単眼の視覚欠如と両眼の視覚欠如が髄鞘形成に与える影響の解析2021
- Author(s)
  長内康幸, バッツルガバツプレブ, 山崎礼二, 山本真理子, 幸喜富, 矢田部恵, 水上浩明, 上野将紀, 小林憲太, 吉村由美子, 篠原良章, 大野伸彦
- Organizer
  第 64 回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] 脳細動脈硬化における血管線維化と脳血管周囲マクロファージの関連2021
- Author(s)
  稲垣健志, 山崎礼二, 長内康幸, 篠原良章, 坂本敦司, 大野伸彦
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] ニュートラルレッドを用いたマウス末梢神経系脱髄病変の新たな検出方法2021
- Author(s)
  山崎礼二、長内康幸、幸喜富、篠原　良章、大野伸彦
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] マウス内包脱髄後の急性運動機能障害と再髄鞘化に伴う機能回復2021
- Author(s)
  山崎礼二、ジェフリーハング、大野伸彦
- Organizer
  第126回日本解剖学会、第98回日本生理学会合同大会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] 多発性硬化症に対する新たな薬剤評価法の開発2021
- Author(s)
  山崎礼二、ジェフリーハング、大野伸彦
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] ニュートラルレッド色素によるマウス末梢神経系脱髄部位の肉眼的検出2021
- Author(s)
  山崎礼二、長内康幸、幸喜富、篠原　良章、大野伸彦
- Organizer
  第 64 回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] 末梢神経系脱髄に対する新たな病変部位標識法の開発2020
- Author(s)
  山崎礼二、長内康幸、幸喜富、篠原　良章、大野伸彦
- Organizer
  第61回日本組織細胞化学会
- Data Source
  KAKENHI-PROJECT-20K22690
[Presentation] 新規内包脱髄マウスモデルの開発2020
- Author(s)
  山崎礼二、ジェフリーハング、大野伸彦
- Organizer
  日本解剖学会第108回関東支部学術集会
- Data Source
  KAKENHI-PROJECT-20K22690

1. 稲垣健志 (20775895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 鈴木秀人 (00508749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 大野伸彦 (10432155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 東森生 (90709643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 長内康幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 篠原良章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamazaki Reiji 山崎 礼二

Research Projects

Research Products

Co-Researchers

脳梗塞におけるDDR1シグナルとリハビリを応用した新たな治療戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic applications for demyelinating diseases via mTOR signallingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the role of perivascular macrophages in stroke using animal models for disease and autopsy brains

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel therapies for multiple sclerosis by targeting creatine metabolism in the brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The Mouse Model of Internal Capsule Demyelination: A Novel Tool for Investigating Motor Functional Changes Caused by Demyelination and for Evaluating Drugs That Promote Remyelination2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Pharmacological treatment promoting remyelination enhances motor function after internal capsule demyelination in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlative light and electron microscopic observation of calcium phosphate particles in a mouse kidney formed under a high-phosphate diet2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dark Rearing in the Visual Critical Period Causes Structural Changes in Myelinated Axons in the Adult Mouse Visual Pathway2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heterogeneity and regulation of oligodendrocyte morphology2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Macroscopic detection of demyelinated lesions in mouse PNS with neutral red dye2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Perivascular macrophages produce type I collagen around cerebral small vessels under prolonged hypertension in rats2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 白質障害領域に分泌される I 型コラーゲンは白質の再生を阻害する2024

Author(s)

Organizer

Data Source

[Presentation] 白質障害領域に沈着する I 型コラーゲンは 再ミエリン化を阻害する2024

Author(s)

Organizer

Data Source

[Presentation] 新たな病変標識法と病態モデルを応用した脱髄研究2023

Author(s)

Organizer

Data Source

[Presentation] The morphological analysis of individual oligodendrocytes in aged mice by serial block face-scanning electron microscopy2023

Author(s)

Yamazaki Reiji 山崎礼二

[Presentation] 白質障害領域に沈着する I 型コラーゲンは再ミエリン化を阻害する2024