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OHNO Nobuhiko  大野 伸彦

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… Alternative Names

大野 伸彦  オオノ ノブヒコ

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Researcher Number 10432155
Other IDs
Affiliation (Current) 2022: 自治医科大学, 医学部, 教授
2022: 生理学研究所, 生体機能調節研究領域, 客員教授
Affiliation (based on the past Project Information) *help 2022: 生理学研究所, 生体機能調節研究領域, 客員教授
2017 – 2022: 自治医科大学, 医学部, 教授
2017: 自治医科大学, 医学部, 准教授
2016: 生理学研究所, 分子細胞生理研究領域, 特任准教授
2014 – 2015: 山梨大学, 総合研究部, 准教授
2007: University of Yamanashi, 大学院・医学工学総合研究部, 助教
2006: 山梨大学, 大学院医学工学総合研究部, 助手
Review Section/Research Field
Principal Investigator
General anatomy (including histology/embryology) / General anatomy (including Histology/Embryology) / Medium-sized Section 48:Biomedical structure and function and related fields
Except Principal Investigator
Medium-sized Section 46:Neuroscience and related fields / General anatomy (including histology/embryology) / Neurochemistry/Neuropharmacology / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 59040:Nutrition science and health science-related / Transformative Research Areas, Section (III)
Keywords
Principal Investigator
軸索 / ミトコンドリア / 脱髄 / 髄鞘 / クライオバイオプシー法 / 生体内凍結技法 / 腫瘍細胞移植モデル / 血清蛋白免疫染色 / 構造的血管 / 機能的血管 … More / 虚血 / クライオピンセット / 浸漬固定法 / 細胞異形性 / 生体内脈管分布 / Mitochondria / Myelination / Demyelination / Electron microscopy / Conductive resin / 有髄軸索 / 小胞体 / ライブイメージング / 3次元超微形態解析 / オルガネラ間相互作用 / オルガネラ相互作用 / シナプス / mitochondria / associated / membranes / リン酸カルシウム / エネルギー分散型X線分析 / 3DSEM … More
Except Principal Investigator
SBF-SEM / ミクログリア / 新規バイオマーカー / 脳、腎糖尿病疾患 / 上皮間葉転換 / 新規治療法開発 / バイオマーカー / SGLT / 高脂肪食負荷マウス / メタボリックシンドローム / 慢性腎機能障害 / メタボローム解析 / 糖尿病性尿細管障害 / スフィンゴ脂質 / オートファゴソーム / ミトコンドリア障害 / 糖尿病性腎機能障害 / 糖尿病性脳機能障害 / 解剖学一般(含組織学・発生学) / 臨床解剖学 / 脳・腎糖尿病疾患 / 髄鞘 / 硫酸化糖鎖 / 末梢神経系 / 糖蛋白質 / グリア細胞 / 海馬 / 大脳皮質 / 協調活動 / カルシウムイメージング / 脳波 / 皮質 / 脳領域間 / イメージング / 網膜アストロサイト / ABCA1 / 眼疾患 / 正常眼圧緑内障 / 緑内障 / アストロサイト / ミューラー細胞 / シナプス / 異種感覚の可塑性 / 生体イメージング / 糖尿病性自律神経障害 / アウエルバッハ神経叢 / 高脂肪食 / 糖尿病 / 神経解剖 / バイオイメージング / 光学顕微鏡支援 / 電子顕微鏡支援 / 磁気共鳴画像支援 / 画像解析支援 Less
  • Research Projects

    (12 results)
  • Research Products

    (82 results)
  • Co-Researchers

    (69 People)
  •  肥満・糖尿病に伴う自律神経障害の病態形成メカニズムの解明と新規治療法の開発

    • Principal Investigator
      志茂 聡
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Health Science University
  •  Advanced Bioimaging Support

    • Principal Investigator
      鍋倉 淳一
    • Project Period (FY)
      2022 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
    • Research Institution
      National Institute for Physiological Sciences
  •  Mechanisms underlying retinal glia-mediated glaucoma

    • Principal Investigator
      小泉 修一
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 46:Neuroscience and related fields
    • Research Institution
      University of Yamanashi
  •  Mechanism for building diversity of neural projections responsible for behavioral selection

    • Principal Investigator
      藤山 文乃
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Hokkaido University
  •  Ultra-fast observation of cortico-hippocampal functional dynamics

    • Principal Investigator
      篠原 良章
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      University of Yamanashi
      Jichi Medical University
  •  Challenge to clarify mechanisms of aging on the basis of technological development of 3 dimensional structural-element correlative analyses in the bodyPrincipal Investigator

    • Principal Investigator
      大野 伸彦
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Jichi Medical University
  •  感覚モダリティ理解のためのミクログリア・シナプス接触の多角的解析

    • Principal Investigator
      和氣 弘明
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 46:Neuroscience and related fields
    • Research Institution
      Nagoya University
  •  Development of novel biomarkers for therapeutic treatment of brain and renal diabetic diseases by focusing on epithelial-mesenchymal transition

    • Principal Investigator
      Saitoh Sei
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Fujita Health University
      National Institute for Physiological Sciences
  •  Mechanisms and roles of homeostatic maintenance of axonal mitochondriaPrincipal Investigator

    • Principal Investigator
      Ohno Nobuhiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Jichi Medical University
      National Institute for Physiological Sciences
  •  Roles of sulfated N-glycans in myelin

    • Principal Investigator
      YOSHIMURA TAKESHI
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
      National Institute for Physiological Sciences
  •  Molecular mechanisms and roles of mitochondrial dynamics in development and diseases of myelinated axonsPrincipal Investigator

    • Principal Investigator
      OHNO Nobuhiko
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      University of Yamanashi
  •  生体内凍結技法による移植腫瘍細胞組織の機能分子形態学的研究Principal Investigator

    • Principal Investigator
      大野 伸彦
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      University of Yamanashi

All 2020 2019 2018 2017 2016 2015 2014 2008 2007 2006

All Journal Article Presentation Patent

  • [Journal Article] Axonal and neuronal degeneration in myelin diseases2019

    • Author(s)
      Ohno Nobuhiko、Ikenaka Kazuhiro
    • Journal Title

      Neuroscience Research

      Volume: 139 Pages: 48-57

    • DOI

      10.1016/j.neures.2018.08.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Journal Article] Methodological Improvements With Conductive Materials for Volume Imaging of Neural Circuits by Electron Microscopy2018

    • Author(s)
      Nguyen Huy Bang、Thai Truc Quynh、Sui Yang、Azuma Morio、Fujiwara Ken、Ohno Nobuhiko
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 12 Pages: 1-10

    • DOI

      10.3389/fncir.2018.00108

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08517, KAKENHI-PROJECT-16K18977
  • [Journal Article] Decreased number and increased volume with mitochondrial enlargement of cerebellar synaptic terminals in a mouse model of chronic demyelination2018

    • Author(s)
      Nguyen Huy Bang、Sui Yang、Thai Truc Quynh、Ikenaka Kazuhiro、Oda Toshiyuki、Ohno Nobuhiko
    • Journal Title

      Medical Molecular Morphology

      Volume: 51 Pages: 208-216

    • DOI

      10.1007/s00795-018-0193-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Journal Article] Improved Serial Sectioning Techniques for Correlative Light-Electron Microscopy Mapping of Human Langerhans Islets2018

    • Author(s)
      Saitoh S, Ohno N, Saitoh Y, Terada N, Shimo S, Aida K, Fujii H, Kobayashi T, Ohno S.
    • Journal Title

      ACTA HISTOCHEMICA ET CYTOCHEMICA

      Volume: 51 Issue: 1 Pages: 9-12

    • DOI

      10.1267/ahc.17020

    • NAID

      130006405037

    • ISSN
      0044-5991, 1347-5800
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08439, KAKENHI-PROJECT-18K17945, KAKENHI-PROJECT-16K08463
  • [Journal Article] Interactions between mitochondria and endoplasmic reticulum in demyelinated axons2018

    • Author(s)
      Thai Truc Quynh、Nguyen Huy Bang、Sui Yang、Ikenaka Kazuhiro、Oda Toshiyuki、Ohno Nobuhiko
    • Journal Title

      Medical Molecular Morphology

      Volume: 印刷中

    • DOI

      10.1007/s00795-018-0212-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H05057, KAKENHI-PROJECT-16K18977
  • [Journal Article] Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.2017

    • Author(s)
      Morizawa YM, *Hirayama Y, *Ohno N, Shibata S, Shigetomi E, Sui Y, Nabekura J, Sato K, Okajima F, Takebayashi H, Okano H, Koizumi S.
    • Journal Title

      Nat Commun.

      Volume: 8 Pages: 28-28

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Journal Article] Polymorphic regulation of mitochondrial fission and fusion modifies phenotypes of microglia in neuroinflammation2017

    • Author(s)
      Katoh M, Wu B, Nguyen HB, Thai TQ, Yamasaki R, Lu H, Rietsch AM, Zorlu MM, Shinozaki Y, Saitoh Y, Saitoh S, Sakoh T, Ikenaka K, Koizumi S, Ransohoff RM, Ohno N.
    • Journal Title

      Sci Rep.

      Volume: 7 Pages: 4942-4942

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Journal Article] GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system2017

    • Author(s)
      Yoshimura T, Hayashi A, Handa-Narumi M, Yagi H, Ohno N, Koike T, Yamaguchi Y, Uchimura K, Kadomatsu K, Sedzik J, Kitamura K, Kato K, Trapp BD, Baba H, Ikenaka K.
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 42257-42257

    • DOI

      10.1038/srep42257

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-WRAPUP-16H01694, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-15H06840, KAKENHI-PROJECT-15K15079, KAKENHI-PROJECT-15K07935, KAKENHI-PROJECT-16K18977, KAKENHI-PLANNED-25117005
  • [Journal Article] Purinergic dysregulation causes hypertensive glaucoma-like optic neuropathy.2017

    • Author(s)
      Shinozaki Y, Kashiwagi K, Namekata K, Takeda A, Ohno N, Robaye B, Harada T, Iwata T, Koizumi S.
    • Journal Title

      JCI Insight.

      Volume: 2 Pages: 93456-93456

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Journal Article] SSSEM による脳組織の3 次元再構築2016

    • Author(s)
      大野伸彦
    • Journal Title

      Clinical Neuroscience

      Volume: 34 Pages: 368-369

    • Data Source
      KAKENHI-PROJECT-26860129
  • [Journal Article] Recent advancement in the challenges to connectomics.2016

    • Author(s)
      Ohno N, Katoh M, Saitoh Y, Saitoh S.
    • Journal Title

      Microscopy

      Volume: 65 Pages: 97-107

    • DOI

      10.1093/jmicro/dfv371

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Journal Article] Proteolipid protein-deficient myelin promotes axonal mitochondrial dysfunction via altered metabolic coupling.2016

    • Author(s)
      Yin X, Kidd GJ, Ohno N, Perkins GA, Ellisman MH, Bastian C, Brunet S, Baltan S, Trapp BD.
    • Journal Title

      J Cell Biol.

      Volume: 215 Pages: 531-542

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Journal Article] Involvement of membrane skeletal molecules in the Schmidt-Lanterman incisure in Schwann cells.2016

    • Author(s)
      Terada N, Saitoh Y, Kamijo A, Ohno S, Ohno N.
    • Journal Title

      Medical Molecular Morphology

      Volume: - Pages: 5-10

    • DOI

      10.1007/s00795-015-0125-0

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460267, KAKENHI-PROJECT-26860129, KAKENHI-PROJECT-16K08463
  • [Journal Article] Rapid specimen preparation to improve the throughput of electron microscopic volume imaging for three-dimensional analyses of subcellular ultrastructures with serial block-face scanning electron microscopy.2016

    • Author(s)
      Thai TQ, Nguyen HB, Saitoh S, Wu B, Saitoh Y, Shimo S, Elewa YH, Ichii O, Kon Y, Takaki T, Joh K, Ohno N.
    • Journal Title

      Medical Molecular Morphology

      Volume: Epub ahead of print Pages: 154-162

    • DOI

      10.1007/s00795-016-0134-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21474, KAKENHI-PROJECT-26860129, KAKENHI-PROJECT-26460449
  • [Journal Article] Conductive resins improve charging and resolution of acquired images in electron microscopic volume imaging.2016

    • Author(s)
      Nguyen HB, Thai TQ, Saitoh S, Wu B, Saitoh Y, Shimo S, Fujitani H, Otobe H, Ohno N.
    • Journal Title

      Scientific reports

      Volume: 6 Pages: 23721-23721

    • DOI

      10.1038/srep23721

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Journal Article] Three-dimensional volume imaging with electron microscopy toward connectome2015

    • Author(s)
      Nobuhiko Ohno, Mitsuhiko Katoh, Yurika Saitoh, Sei Saitoh, Shinichi Ohno
    • Journal Title

      Microscopy

      Volume: 64 Pages: 17-26

    • DOI

      10.1093/jmicro/dfu112

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Journal Article] Mitochondrial Fission Augments Capsaicin-induced Axonal Degeneration2015

    • Author(s)
      Hao Chiang, Nobuhiko Ohno, Yu-Lin Hsieh, Don J. Mahad, Shin Kikuchi, Hitoshi Komuro, Sung-Tsang Hsieh, Bruce D. Trapp
    • Journal Title

      Acta Neuropathol

      Volume: 129 Pages: 81-96

    • DOI

      10.1007/s00401-014-1354-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26860129, KAKENHI-PROJECT-15K01419, KAKENHI-PROJECT-25750207
  • [Journal Article] Differential roles of microglia and monocytes in the inflamed central nervous system2014

    • Author(s)
      Ryo Yamasaki, Haiyan Lu, Oleg Butovsky, Nobuhiko Ohno, Anna M. Rietsch, Ron Cialic, Pauline M. Wu, Camille E. Doykan, Jessica Lin, Anne C. Cotleur, Grahame Kidd, Musab M. Zorlu, Nathan Sun, Weiwei Hu, LiPing Liu, Jar-Chi Lee, Sarah E. Taylor, Lindsey Uehlein, Debra Dixon, Jinyu Gu, Crina M. Floruta, Min Zhu, et al.
    • Journal Title

      J Exp Med.

      Volume: 211 Pages: 1533-1549

    • DOI

      10.1084/jem.20132477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Journal Article] Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons2014

    • Author(s)
      Nobuhiko Ohno, Hao Chiang, Don J. Mahad, Grahame J. Kidd, LiPing Liu, Richard M. Ransohoff, Zu-Hang Sheng, Hitoshi Komuro, Bruce D. Trapp
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 111 Pages: 9953-9958

    • DOI

      10.1073/pnas.1401155111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Journal Article] SBF-SEMによる生体内3次元微細構造観察の試料作製とその応用2014

    • Author(s)
      大野伸彦、齊藤成、齊藤百合花、大野伸一
    • Journal Title

      顕微鏡

      Volume: 49 Pages: 166-170

    • NAID

      130007701728

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Journal Article] Distribution of immunoglobulin-producing cells in immunized mouse spleensrevealed with ″in vivo cryotechnique″.2008

    • Author(s)
      Saitoh S, Terada N, Ohno N, Ohno S.
    • Journal Title

      J Immunol Methods 331(1-2)

      Pages: 114-126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Raman microscopy of freeze-dried mouse eyeball-slice in conjunction with the ″in vivo cryotechnique″.2007

    • Author(s)
      Terada N, Ohno N, Saitoh S, Fujii Y, Ohguro H, Ohno S.
    • Journal Title

      Microsc Res Tech 70(7)

      Pages: 634-639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Immunohistochemical analyses on serum proteins in nephrons of protein-overload mice by "in vivo cryotechnique".2007

    • Author(s)
      Zhou D, Ohno N, Terada N, Li Z, Morita H, Inui K, Yoshimura A, Ohno S.
    • Journal Title

      Histol Histopathol. 22(2)

      Pages: 137-145

    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Recent development of in vivo cryotechnique to cryobiopsy for living animals.2007

    • Author(s)
      Ohno N, Terada N, Saitoh S, Zhou H, Fujii Y, Ohno S.
    • Journal Title

      Histol Histopathol 22(11)

      Pages: 1281-1290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Chondrosarcoma with myxoid change: a study using a quick-freezing and deep-etching method.2007

    • Author(s)
      Hemmi A, Osaka S, Sumie O, Nemoto N, Ohno N, Terada N, Fujii Y, Ohno S.
    • Journal Title

      Ultrastruct Pathol 31(4)

      Pages: 293-302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Interaction of membrane skeletal protein, protein 4. 1B and p55, and sodiem bicarbonate cotransporterl in mouse renal S1-S2 proximal tubules.2007

    • Author(s)
      Terada N, Ohno N, Saitoh S, Seki G, Komada M, Suzuki T, Yamakawa H, Soleimani M, Ohno S.
    • Journal Title

      J Histochem Cytochem. 55(12)

      Pages: 1199-1206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Extracellular space in mouse cerebellar cortex revealed by in vivo cryotechnique.(2007)505: 292-301.2007

    • Author(s)
      Ohno N, Terada N, Saitoh S, Ohno S.
    • Journal Title

      J Comp Neurol 505(3)

      Pages: 292-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Conservation and alteration of chromosome territory arrangements in thyroid carcinoma cell nuclei.2007

    • Author(s)
      Murata S, Nakazawa T, OhnoN, Terada N, Iwashina M, Mochizuki K, Kondo T, Nakamura N, Yamane T, Iwasa S, Ohno S, Katoh R.
    • Journal Title

      Thyroid 17(6)

      Pages: 489-496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Involvement of follicular basement membrane and vascular endothelium in blood-follicle barrier formation of mice revealed by ″in vivo cryotechnique″.2007

    • Author(s)
      Zhou H, Ohno N, Terada N, Saitoh S, Fujii Y, Ohno S.
    • Journal Title

      Reproduction 134(2)

      Pages: 307-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Immunohistochemical detection of hypoxia in mouse liver tissues treated with pimonidazole using ″in vivo cryotechnique″.2007

    • Author(s)
      Terada N, Ohno N, Saitoh S, Ohno S.
    • Journal Title

      Histochem Cell Biol 128(3)

      Pages: 253-261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Expression of protein 4.1G in Schwann cells of the peripheral nervous system.2006

    • Author(s)
      Ohno N, Terada N, Yamakawa H, Komada M, Ohara O, Trapp BD, Ohno S.
    • Journal Title

      J Neurosci Res. 84(3)

      Pages: 568-577

    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Morphological and histochemical analyses of living mouse livers by new 'cryobiopsy' technique.2006

    • Author(s)
      Fujii Y, Ohno N, Li Z, Terada N, Baba T, Ohno S.
    • Journal Title

      J Electron Microsc. 55(2)

      Pages: 113-122

    • NAID

      10018183523

    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Immunolocalization of serum proteins in living mouse glomeruli under various hemodynamic conditions by "in vivo cryotechnique".2006

    • Author(s)
      Li Z, Ohno N, Terada N, Ohno S.
    • Journal Title

      Histochem Cell Biol. 126(3)

      Pages: 399-406

    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Immunohistochemical detection of phosphorylated rhodopsin in light-exposed retina of living mouse with in vivo cryotechnique.2006

    • Author(s)
      Terada N, Ohno N, Ohguro H, Li Z, Ohno S.
    • Journal Title

      J Histochem Cytochem. 54(4)

      Pages: 479-486

    • Data Source
      KAKENHI-PROJECT-18890075
  • [Journal Article] Histochemical analyses of living mouse liver under different hemodynamic conditions by "in vivo cryotechnique".2006

    • Author(s)
      Ohno N, Terada N, Ohno S.
    • Journal Title

      Histochem Cell Biol. 126(3)

      Pages: 389-398

    • Data Source
      KAKENHI-PROJECT-18890075
  • [Patent] 形態観察用試料の調整方法及びそれに用いる液体処理用器具、試料台.2015

    • Inventor(s)
      大野 伸彦, 乙部 博英, 藤谷 洋
    • Industrial Property Rights Holder
      大野 伸彦, 乙部 博英, 藤谷 洋
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-177235
    • Filing Date
      2015-09-09
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] 3D電顕が見せる新しいイメージと応用2020

    • Author(s)
      大野伸彦
    • Organizer
      第50回日本腎臓学会東部学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21506
  • [Presentation] 3D architectures of primary cilia of collecting duct cells in rat kidney revealed by SBF-SEM2019

    • Author(s)
      齊藤 成, 熊本 海生航, 大野 伸彦 , 高橋 和男, 長尾 静子
    • Organizer
      第79回日本解剖学会中部支部学術集会
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] SGLT inhibitor and Impaired Phospholipid Metabolism of Proximal Tubular Epithelium in Diet-Induced Obesity (DIO) Mouse Kidney2019

    • Author(s)
      Sei Saitoh, Takashi Takaki, Satoshi Shimo, Nobuhiko Ohno
    • Organizer
      第125回日本解剖学会
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] 高脂肪食摂取下でのフロリジン投与がアウエルバッハ神経叢に与える影響2019

    • Author(s)
      志茂聡、齊藤成、Huy Bang Nguyen、Truc Quynh Thai、 生友聖子、村松憲、大野伸彦
    • Organizer
      第79回日本解剖学会中部支部学術集会
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] 髄鞘疾患における細胞内オルガネラ変化のスーパーイメージング2019

    • Author(s)
      大野 伸彦
    • Organizer
      第124回日本解剖学会総会・全国学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Voxel-based morphometry of primary cilia in collecting duct of rat kidney on SBF-SEM2019

    • Author(s)
      Sei Saitoh, Kanako Kumamoto, Nobuhiko Ohno, and Shizuko Nagao
    • Organizer
      際13回日中組織化学セミナー
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] Sodium-glucose co-transporter (SGLT) inhibitor restores lost axonal varicosities of the myenteric plexus in a mouse model of high-fat diet-induced obesity2019

    • Author(s)
      Satoshi Shimo, Sei Saitoh, Huy Bang Nguyen, Truc Quynh Thai, Masako Ikutomo, Ken Muramatsu, and Nobuhiko Ohno
    • Organizer
      第125回日本解剖学会
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] 慢性脱髄モデルマウスにおける小脳シナプス終末の変化2018

    • Author(s)
      Huy Bang Nguyen、Yang Sui、Truc Quynh Thai、池中 一裕、小田 賢幸、大野 伸彦
    • Organizer
      第59回日本組織細胞化学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Volume EM Imaging of The White Matter2018

    • Author(s)
      Nobuhiko Ohno
    • Organizer
      日本顕微鏡学会第74回学術講演会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] SGLT inhibitor and Impaired Phospholipid Metabolism of Proximal Tubular Epithelium in Diet-Induced Obesity (DIO) Mouse Kidney2018

    • Author(s)
      齊藤 成、高木 孝士、志茂 聡、大野 伸彦
    • Organizer
      第78回日本解剖学会中部支部学術集会 (富山県)
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] Correlative Light-electron Microscopy Mapping of Human Langerhans Islets2018

    • Author(s)
      Sei Saitoh, Nobuhiko Ohno, Yurika Saitoh, Nobuo Terada, Satoshi Shimo, Kaoru Aida, Hideki Fujii, Tetsuro Kobayashi and Shinichi Ohno
    • Organizer
      日本顕微鏡学会第74回学術講演会 (久留米シティプラザ 福岡県)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] 生物組織の電子顕微鏡ボリュームイメージングに資する導電性素材と金属染色2018

    • Author(s)
      大野 伸彦
    • Organizer
      第27回素材工学研究懇談会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] SBF-SEMによる3次元微細構造観察が明らかにする新しい中枢神経系のグリア細胞像2017

    • Author(s)
      大野伸彦
    • Organizer
      第69回日本細胞生物学会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Increased connection between mitochondria and endoplasmic reticulum in demyelinated axons2017

    • Author(s)
      Thai TQ, Nguyen HB, Sui Y, Bao Wu, Zheng Huang, Ikenaka K, Ohno N.
    • Organizer
      第60回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Organelle Dynamics in Myelin Diseases Revealed by SBF-SEM2017

    • Author(s)
      Ohno N.
    • Organizer
      2017 Yonsei Univ-Korea Univ-NIPS Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Improved Serial Sectioning Techniques for Correlative Light-Electron Microscopy Mapping of Human Langerhans Islets.2017

    • Author(s)
      Sei Saitoh, Nobuhiko Ohno, Yurika Saitoh, Nobuo Terada, Satoshi Shimo, Kaoru Aida, Hideki Fujii, Tetsuro Kobayashi and Shinichi Ohno.
    • Organizer
      第12回日中合同組織細胞化学セミナー (2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] A novel model: optical stimulation causes axonal degeneration mediated by axoplasmic calcium.2017

    • Author(s)
      Sui Y, Nguyen HB, Thai TQ, Ikenaka K, Ohno N.
    • Organizer
      第60回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Microscopic and LC-MS Analyses of Lipid Metabolism Abnormality in Proximal Renal Tubule of Diet Induced Obesity Mice.2017

    • Author(s)
      Sei Saitoh, Takashi Takaki, Satoshi Shimo, Truc Quynh Thai, Huy Bang Nguyen, Nobuhiko Ohno.
    • Organizer
      The 1st ABiS Symposium- Towards the Future of Advanced Bioimaging for Life Sciences
    • Place of Presentation
      Okazaki Conference Center, NINS 愛知県岡崎市明大寺町
    • Year and Date
      2017-02-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] Microscopic and LC-MS Analyses of Lipid Metabolism Abnormality in Proximal Renal Tubule of Diet Induced Obesity Mice.2017

    • Author(s)
      Saitoh Sei, Takaki Takashi, Satoshi Shimo, Truc Quynh Thai, Huy Bang Nguyen, Ohno Nobuhiko.
    • Organizer
      ABiS 1st meeting (2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] Relationship between axonal mitochondria and endoplasmic reticulum in demyelinating diseases2017

    • Author(s)
      Thai TQ, Nguyen HB, Sui Y, Ikenaka K, Ohno N.
    • Organizer
      第49回日本臨床分子形態学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] A novel model: optical stimulation causes axonal degeneration mediated by axoplasmic calcium.2017

    • Author(s)
      Sui Y, Nguyen HB, Thai TQ, Ikenaka K, Ohno N.
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Alterations of synaptic terminals in cerebellum of the chronic demyelination mouse model2017

    • Author(s)
      Nguyen HB, Sui Y, Thai TQ, Ikenaka K, Ohno N.
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] 3次元超微形態解析により見えてくる疾患の病態生理2017

    • Author(s)
      大野伸彦
    • Organizer
      第49回日本臨床分子形態学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Increased connection between mitochondria and endoplasmic reticulum in demyelinated axons2017

    • Author(s)
      Nguyen HB, Sui Y, Thai TQ, Ikenaka K, Ohno N..
    • Organizer
      第60回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Serial block-face imaging combined with carbon-based conductive resins for pathophysiological analyses of demyelinating diseases2017

    • Author(s)
      Nobuhiko Ohno, Huy Bang Nguyen, Mitsuhiko Katoh, Yang Sui, Truc Quynh Thai, Kazuhiro Ikenaka
    • Organizer
      2017 Connectomics Berlin
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] オルガネラ動態の生理機能に迫る最先端3次元微細構造解析法2016

    • Author(s)
      大野伸彦
    • Organizer
      第63回中部日本生理学会
    • Place of Presentation
      岡崎コンファレンスセンター(愛知県岡崎市)
    • Year and Date
      2016-11-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Microscopy and LC-MS analyses of lipid metabolism abnormality in proximal convoluted tubules on type 2 diabetes2016

    • Author(s)
      齊藤 成、高木 孝士 、志茂 聡、Truc Quynh Thai、Huy Bang Nguyen、大野 伸彦
    • Organizer
      生体ボリュームイメージング研究会&生理研研究会合同ワークショップ
    • Place of Presentation
      Okazaki Conference Center, NINS 愛知県岡崎市明大寺町
    • Year and Date
      2016-11-16
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] Polarization of energy metabolism and mitochondrial behavior in myelinated axons2016

    • Author(s)
      大野伸彦
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] 生物組織のSEM連続断面観察法に資する樹脂の開発2016

    • Author(s)
      大野伸彦
    • Organizer
      日本顕微鏡学会第72回学術講演会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-06-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] 2型糖尿病性近位腎尿細管障害における脂質代 謝異常の顕微鏡解析2016

    • Author(s)
      齊藤 成 ,高木 孝士,志茂 聡,タイ トラック クエン,寺嶋 博,大野 伸彦 。
    • Organizer
      日本顕微鏡学会 第72回学術講演会.
    • Place of Presentation
      仙台国際センター 宮城県仙台市青葉区青葉山
    • Year and Date
      2016-06-14
    • Data Source
      KAKENHI-PROJECT-16K08439
  • [Presentation] 有髄軸索におけるミトコンドリア恒常性2016

    • Author(s)
      大野伸彦
    • Organizer
      ミトコンドリアサイエンスワークショップ2016
    • Place of Presentation
      福岡リーセントホテル(福岡県福岡市)
    • Year and Date
      2016-07-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] 試料作製法の進歩が拓くSEM連続断面観察法の展望2016

    • Author(s)
      大野伸彦
    • Organizer
      第121回日本解剖学会総会
    • Place of Presentation
      ビッグパレット福島(福島県郡山市)
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] 髄鞘による軸索のオルガネラ動態制御とその破綻2016

    • Author(s)
      大野伸彦
    • Organizer
      第59回神経化学会大会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] Successful applications and pitfalls in three dimensional ultrastructural analyses of biological specimens with SEM2016

    • Author(s)
      大野伸彦
    • Organizer
      日本顕微鏡学会第59回シンポジウム
    • Place of Presentation
      帝京平成大学池袋キャンパス(東京都豊島区)
    • Year and Date
      2016-11-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] 有髄神経におけるミトコンドリア恒常性の維持機構2016

    • Author(s)
      大野伸彦
    • Organizer
      第2回日本ミエリン研究会
    • Place of Presentation
      横浜ランドマークセンター(神奈川県横浜市)
    • Year and Date
      2016-07-23
    • Data Source
      KAKENHI-PROJECT-16K18977
  • [Presentation] SEM断面観察法をより簡便にする試料作製法の進歩2015

    • Author(s)
      大野伸彦、乙部博英、藤谷洋
    • Organizer
      日本臨床分子形態学会
    • Place of Presentation
      長崎大学(長崎県長崎市)
    • Year and Date
      2015-09-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] Mitochondrial fission and elongation in microglia induced by activation with LPS2015

    • Author(s)
      Katoh M, Wu B, Nguyen HB, Thai TQ, Sakoh T, Saitoh Y, Saitoh S, Shinozaki Y, Koizumi S, Ohno N
    • Organizer
      日本神経化学会
    • Place of Presentation
      大宮ソニックシティ(埼玉県さいたま市)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] Development of conductive resin to facilitate 3D ultrastructural imaging in life science2015

    • Author(s)
      Ohno N, Otobe H, Fujitani H
    • Organizer
      The 2nd East-Asia Microscopy Conference Young Scientists Satellite Meeting
    • Place of Presentation
      淡路夢舞台(兵庫県淡路市)
    • Year and Date
      2015-11-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] 有髄神経における神経活動依存性のミトコンドリア動態2015

    • Author(s)
      大野伸彦
    • Organizer
      第120回 日本解剖学会総会・全国学術集会
    • Place of Presentation
      神戸国際会議場・展示場(兵庫県)
    • Year and Date
      2015-03-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] SBF-SEMを用いた3次元微細構造観察のターゲットと試料作製2014

    • Author(s)
      大野伸彦
    • Organizer
      日本顕微鏡学会第70回記念学術講演会
    • Place of Presentation
      幕張メッセ 国際会議場(千葉県)
    • Year and Date
      2014-05-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] 髄鞘の異常におけるオルガネラ動態の変化2014

    • Author(s)
      大野伸彦
    • Organizer
      第55回日本組織細胞化学会総会・学術集会
    • Place of Presentation
      松本市中央公民館(長野県)
    • Year and Date
      2014-09-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] 末梢神経軸索障害におけるミトコンドリア動態の役割2014

    • Author(s)
      大野伸彦
    • Organizer
      第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
    • Place of Presentation
      奈良県文化会館、奈良県新公会堂(奈良県)
    • Year and Date
      2014-09-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] SBF-SEMの応用による疾病モデルおよびヒト組織の3次元微細構造観察2014

    • Author(s)
      大野伸彦、齊藤成 、齊藤百合花 、井上朋大 、加藤良平 、大野伸一
    • Organizer
      第46回日本臨床分子形態学会総会・学術集会
    • Place of Presentation
      TKP市ヶ谷カンファレンスセンター(東京都)
    • Year and Date
      2014-10-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26860129
  • [Presentation] クライオバイオプシー法による移植ヒト肺癌腫瘍モデルにおける機能的血管の構築の検討2007

    • Author(s)
      大野伸彦、寺田信生、白玉勤、齊藤成、藤井靖久、大野伸一.
    • Organizer
      日本解剖学会 中部地方会
    • Place of Presentation
      愛知医科大学
    • Year and Date
      2007-10-13
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Presentation] クライオバイオプシー法によるヒト腫瘍細胞移植マウスモデルの組織学的解析2007

    • Author(s)
      大野伸彦、寺田信生、斎藤成、藤井靖久、白玉勤、大野伸一.
    • Organizer
      日本顕微鏡学会
    • Place of Presentation
      新潟コンベンションセンター
    • Year and Date
      2007-05-22
    • Data Source
      KAKENHI-PROJECT-18890075
  • [Presentation] 生体内凍結試料を用いたマウス小脳間質組織の形態計測解析2007

    • Author(s)
      大野伸彦、寺田信生、斎藤成、大野伸一.
    • Organizer
      合同学術集会 第48回日本組織細胞化学会総会 第39回日本臨床分子形態学会総会
    • Place of Presentation
      甲府市総合市民会館
    • Year and Date
      2007-09-29
    • Data Source
      KAKENHI-PROJECT-18890075
  • 1.  Saitoh Sei (10456444)
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  • 2.  YOSHIMURA TAKESHI (60402567)
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  • 3.  KADOMATSU Kenji (80204519)
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  • 4.  UCHIMURA Kenji (20450835)
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  • 5.  BABA Hiroko (40271499)
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  • 20.  村松 憲 (00531485)
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  • 39.  佐藤 良勝 (30414014)
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  • 56.  舟橋 啓 (70324548)
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  • 59.  TERADA Nobuo
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  • 60.  YAMAGUCHI Takumi
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  • 61.  YAGI Maho
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  • 62.  YAGI Hirokazu
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  • 63.  KIKUCHI Shin
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  • 69.  池中 一裕
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