BABA Hiroko 馬場広子

Researcher Number	40271499
Affiliation (Current)	2020: 東京薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2009 – 2018: Tokyo University of Pharmacy and Life Science, 薬学部, 教授 2000 – 2007: Tokyo University of Pharmacy and Life Sciences, Professor, 薬学部, 教授 1998 – 1999: 名古屋市立大学, 医学部, 講師 1995 – 1996: 岡崎国立共同研究機構, 生理学研究所, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Pain science / Neurochemistry/Neuropharmacology Except Principal Investigator Biological Sciences / Neuroscience in general / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator ミエリン / オリゴデンドロサイト / シュワン細胞 / ランビエ絞輪 / 髄鞘 / 電位依存性ナトリウムチャネル / スルファチド / 有髄神経 / 電位依存性カリウムチャネル / グリア細胞 … More Except Principal Investigator ミエリン / オリゴデンドロサイト / 電位依存性カリウムチャネル / ランビエの紋輪 / 脱髄性疾患 / 神経伝導 / myelin proteolipid protein / グリア細胞 / paranodal junction / 脂質 / 神経科学 / 糖鎖 / 脳神経疾患 / 免疫学 / ガングリオシド / 末梢神経伝導速度 / ギラン・バレー症候群 / ミエリンプロテオリピド蛋白質 / アンチセンスオリゴヌクレオチド / ホスホロチオエ-ト化 / 遺伝子治療 / 脱髄 / anti-sense olilgonucleotide / phosphorothioate / gene therapy / demyelination / myelin / 有髄神経軸策 / イオンチャネルクラスタリング / ランビエの絞輪 / パラノード / 有髄神経軸索 / myelinated fiber / ion channel clustering / Node of Ranvier / paranode / アストロサトイ / PDGFα受容体 / PLP / シスタチンC / 細胞系譜 / Glial Cell Missing / アストロサイト / レトロウィルス / GFAP / GLAST / oligodendrocyte / astrocyte / PDGFα receptor / Cystatin C / 小脳顆粒細胞 / 有髄軸索 / ランビエ絞輪 / 電位依存性K^+チャネル / 電位依存性Na^+チャネル / シナプス形成 / グルタミン酸受容体 / Ca<2+>センサータンパク / GFP / Voltage-gated K channel / Voltage-gated Na channel / Synapse formation / node of Ranvier / myelination / cerebellar granule neuron / 髄鞘 / 硫酸化糖鎖 / 末梢神経系 / 糖蛋白質 Less

Regulation of peripheral nerve function through post-translational modificationsPrincipal Investigator
- Principal Investigator
  
  Baba Hiroko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo University of Pharmacy and Life Science
Roles of sulfated N-glycans in myelin
- Principal Investigator
  
  YOSHIMURA TAKESHI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
  National Institute for Physiological Sciences
神経回路発達におけるミクログリアの機能解明Principal Investigator
- Principal Investigator
  
  馬場広子
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
Production mechanism and functional role of myelin protein produced by stop codon readthroughPrincipal Investigator
- Principal Investigator
  
  BABA Hiroko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo University of Pharmacy and Life Science
Regulation of axonal transport by local interaction with myelinPrincipal Investigator
- Principal Investigator
  
  BABA Hiroko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo University of Pharmacy and Life Science
A role of CD9 in pain pathway of spinal dorsal hornPrincipal Investigator
- Principal Investigator
  
  BABA Hiroko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tokyo University of Pharmacy and Life Science
抗ガングリオシド抗体による神経疾患発症の分子機構
- Principal Investigator
  
  結城伸泰
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Dokkyo Medical University
グリアによる神経軸索上機能分子の発現および局在化調節機構の解明Principal Investigator
- Principal Investigator
  
  馬場広子
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
Studies on molecular mechanisms of ion channel clustering at the nodes of Ranvier.Principal Investigator
- Principal Investigator
  
  BABA Hiroko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo University of Pharmacy and Life Science
Molecular mechanisms of subcellular localization of the voltage-gated Ion channels
- Principal Investigator
  
  IKENAKA Kazuhiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Okazaki National Research Institutes
神経伝導ブロックによる軸索変性機序の解明および治療の試み
- Principal Investigator
  
  IKENAKA Kazuhiro
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okazaki National Research Institutes
グリア細胞によるイオンチャンネルの発現と局在の調節機構
- Principal Investigator
  
  IKENAKA Kazuhiro
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Physiological Sciences
Analysis of glial cell lineage based on their diverse functions and clarification of the molecular mechanisms that generate them
- Principal Investigator
  
  IKENAKA Kazuhiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Neuroscience in general
- Research Institution
  National Institute for Physiological Sciences
Molecular Mechanisms for K+ channel clustering on myelinated axonsPrincipal Investigator
- Principal Investigator
  
  BABA Hiroko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagoya City University
Analysis of Gene Defect in Hypomyelinating Diseases and Development of the Therapeutic Methods.
- Principal Investigator
  
  IKENAKA Kazuhiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Okazaki National Institutes

All 2018 2017 2016 2015 2013 2011 2010 2009 2005 2004

All Journal Article Presentation Book

[Book] 糖脂質とミエリン機能(「蛋白質核酸酵素」別冊「神経糖鎖生物学」)2004
- Author(s)
  馬場広子
- Total Pages
  222
- Publisher
  共立出版株式会社
- Data Source
  KAKENHI-PROJECT-15082208
[Journal Article] GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system2017
- Author(s)
  Yoshimura T, Hayashi A, Handa-Narumi M, Yagi H, Ohno N, Koike T, Yamaguchi Y, Uchimura K, Kadomatsu K, Sedzik J, Kitamura K, Kato K, Trapp BD, Baba H, Ikenaka K.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Pages: 42257-42257
- DOI
  10.1038/srep42257
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-16H01694, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-15H06840, KAKENHI-PROJECT-15K15079, KAKENHI-PROJECT-15K07935, KAKENHI-PROJECT-16K18977, KAKENHI-PLANNED-25117005
[Journal Article] 末梢ミエリンと脱髄性ニューロパチー2013
- Author(s)
  馬場　広子
- Journal Title
  
  脳２１
  
  Volume: 16 Pages: 420-426
- Data Source
  KAKENHI-PROJECT-24500449
[Journal Article] Demyelinating neuropathy2013
- Author(s)
  Hiroko Baba
- Journal Title
  
  Peripheral Nerve
  
  Volume: 24 Pages: 210-213
- Data Source
  KAKENHI-PROJECT-24500449
[Journal Article] グリアによる神経軸索機能の調節2005
- Author(s)
  馬場広子
- Journal Title
  
  神経研究の進歩 49・6
  
  Pages: 861-866
- Data Source
  KAKENHI-PROJECT-15082208
[Journal Article] Isolation of cystatin C via functional cloning of astrocyte differentiation factors.2004
- Author(s)
  Kumada T, Hasegawa A, Iwasaki Y, Baba H, Ikenaka K
- Journal Title
  
  Dev.Neurosci. 26
  
  Pages: 68-76
- Data Source
  KAKENHI-PROJECT-15082208
[Presentation] Peripheral nerve dysfunction mediated by translational readthrough of myelin protein zero mRNA2018
- Author(s)
  Baba Hiroko, Yamaguchi Yoshihide
- Organizer
  Cold Spring Harbor Asia; Novel Insights into Glia Function & Dysfunction
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07069
[Presentation] Increased ratio of large myelin protein zero (L-MPZ) in myelin leads to Charcot- Marie-Tooth disease like phenotype2018
- Author(s)
  大谷　嘉典、山口　宜秀、崔　晶晶、馬場　広子
- Organizer
  第40日本生物学的精神医学会，第61回日本神経化学大会　合同年会
- Data Source
  KAKENHI-PROJECT-16K07069
[Presentation] Translational readthrough isoform, L-MPZ, exhibits unique localization pattern and functional aspects in the PNS myelin which differ from canonical myelin protein zero (P0/MPZ)2018
- Author(s)
  Yamaguchi Yoshihide, Otani Yoshinori, Cui Jingjing, Baba Hiroko
- Organizer
  Neuroscience 2018, Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07069
[Presentation] Replacement of P0 with L-MPZ in myelin caused peripheral neuropathy2018
- Author(s)
  Otani Yoshinori, Yoamaguchi Yoshihide, Cui Jingjing, Baba Hiroko
- Organizer
  15th Meeting of the Asian-Pacific Society for Neurochemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07069
[Presentation] Sulfated N-glycans modulate myelination in the peripheral nervous system.2016
- Author(s)
  吉村武, 半田麻衣, 林明子, 矢木宏和, 山口宜秀, 内村健治, 門松健治, 加藤晃一, 馬場広子, 池中一裕
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Data Source
  KAKENHI-PROJECT-15H06840
[Presentation] Loss of PLD4 in activated microglia affect myelination in brain development2015
- Author(s)
  馬場　広子
- Organizer
  12th Biennial ISN Satellite Meeting Myelin Biology 2015: Glial Neuronal Interactionsシンポジウム
- Place of Presentation
  フィッツロイアイランド、オーストラリア
- Year and Date
  2015-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26117517
[Presentation] Regulation of myelination in brain2015
- Author(s)
  馬場　広子
- Organizer
  第56回日本神経学会大会シンポジウム
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PUBLICLY-26117517
[Presentation] 硫酸化糖鎖は末梢神経系髄鞘の形成を制御する2015
- Author(s)
  吉村武、半田（鳴海）麻衣、林明子、矢木宏和、内村健治、門松健治、加藤晃一、Bruce D. Trapp, 馬場広子、池中一裕
- Organizer
  糖鎖科学中部拠点・第12回若手の力フォーラム
- Place of Presentation
  名城大学薬学部（愛知県名古屋市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15H06840
[Presentation] GlcNAc6ST-1はN結合型糖鎖の硫酸化を介して末梢神経系の髄鞘形成を制御する2015
- Author(s)
  吉村武、半田麻衣、林明子、矢木宏和、内村健治、門松健治、加藤晃一、馬場広子、池中一裕
- Organizer
  第5回名古屋大学医学系研究科・生理学研究所合同シンポジウム
- Place of Presentation
  生理学研究所大会議室（愛知県岡崎市）
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-15H06840
[Presentation] GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system.2015
- Author(s)
  Takeshi Yoshimura, Mai Handa-Narumi, Akiko Hayashi, Hirokazu Yagi, Yoshihide Yamaguchi, Kenji Uchimura, Kenji Kadomatsu, Kunio Kitamura, Koichi Kato, Bruce D. Trapp, Hiroko Baba, Kazuhiro Ikenaka.
- Organizer
  12th Biennial ISN Satellite Meeting Myelin Biology 2015
- Place of Presentation
  Fitzroy Island (Australia)
- Year and Date
  2015-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06840
[Presentation] GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system2015
- Author(s)
  Takeshi Yoshimura, Mai Handa-Narumi, Akiko Hayashi, Hirokazu Yagi, Yoshihide Yamaguchi, Kenji Uchimura, Kenji Kadomatsu, Koichi Kato, Hiroko Baba, Kazuhiro Ikenaka
- Organizer
  第20回グリア研究会
- Place of Presentation
  名古屋市立大学医学部研究棟（愛知県名古屋市）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15H06840
[Presentation] GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system2015
- Author(s)
  Takeshi Yoshimura, Akiko Hayashi, Kenji Uchimura, Kenji Kadomatsu, Yoshihide Yamaguchi, Hiroko Baba, Kazuhiro Ikenaka
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮ソニックシティ（埼玉県さいたま市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15H06840
[Presentation] 脱髄性末梢神経障害と髄鞘再生2013
- Author(s)
  馬場　広子
- Organizer
  第２４回日本末梢神経学会学術集会
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-24500449
[Presentation] パラノーダルジャンクション形成不全時における小脳プルキンエ細胞の変化2011
- Author(s)
  石橋智子、馬場広子
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光(石川県)
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-21500355
[Presentation] Disruption of the axo-glial interaction causes focal axonal damages in cerebellar Purkinje neurons2011
- Author(s)
  Hiroko Baba
- Organizer
  10^<th> Biennial Meeting of the Asian Pacific Society for Neurochemistry
- Place of Presentation
  Phuket, Thailand
- Data Source
  KAKENHI-PROJECT-21500355
[Presentation] Disruption of axo-glial interaction causes focal damages in cerebellar Purkinje neurons2011
- Author(s)
  Tomoko Ishibashi, Hiroko Baba
- Organizer
  10th Biennial ISN satellite Meeting on Myelin Biology
- Place of Presentation
  Crete (Greece)
- Data Source
  KAKENHI-PROJECT-21500355
[Presentation] Disruption of axo-glial interaction causes focal damages in cerebellar Purkinje neurons2011
- Author(s)
  Tomoko Ishibashi, Hiroko Baba
- Organizer
  10^<th> Biennial International Society for Neurochemistry satellite Meeting on Myelin Biology
- Place of Presentation
  Crete(Greece)
- Data Source
  KAKENHI-PROJECT-21500355
[Presentation] Disruption of the axo-glial interaction causes focal axonal damages in cerebellar Purkinje neurons.2010
- Author(s)
  Hiroko Baba
- Organizer
  The 10^<th> Biennial Meeting of the Asian Pacific Society for Neurochemistry
- Place of Presentation
  Phuket, Thailand
- Data Source
  KAKENHI-PROJECT-21500355
[Presentation] 末梢神経系パラノーダル・ジャンクション形成異常における軸索の変化2009
- Author(s)
  児玉明子、立石陽子、石橋智子、馬場広子
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  伊香保(群馬県)
- Year and Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-21500355

1. IKENAKA Kazuhiro (00144527)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
2. YAMAGUCHI Yoshihide (50311832)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. HAYASHI Akiko (90232090)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. NAKAHIRA Kensuke (10260043)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. KAGAWA Tetsushi (50270484)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. FUJIMOTO Ichiro (70264710)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. IWASAKI Yasuno (40311196)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OHNO Nobuhiko (10432155)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. ONO Katsuhiko (30152523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YOSHIMURA TAKESHI (60402567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. KADOMATSU Kenji (80204519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. UCHIMURA Kenji (20450835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
13. 結城伸泰 (60285913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 石橋智子 (50453808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKANISHI Hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YANO Noriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Otani Yoshinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. YAMAGUCHI Takumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. YAGI Maho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. YAGI Hirokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 安藤明子

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
22. 加藤晃一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

BABA Hiroko 馬場 広子

Research Projects

Research Products

Co-Researchers

Regulation of peripheral nerve function through post-translational modificationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of sulfated N-glycans in myelin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経回路発達におけるミクログリアの機能解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Production mechanism and functional role of myelin protein produced by stop codon readthroughPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of axonal transport by local interaction with myelinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A role of CD9 in pain pathway of spinal dorsal hornPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抗ガングリオシド抗体による神経疾患発症の分子機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

グリアによる神経軸索上機能分子の発現および局在化調節機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on molecular mechanisms of ion channel clustering at the nodes of Ranvier.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of subcellular localization of the voltage-gated Ion channels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経伝導ブロックによる軸索変性機序の解明および治療の試み

Principal Investigator

Project Period (FY)

Research Category

Research Institution

グリア細胞によるイオンチャンネルの発現と局在の調節機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of glial cell lineage based on their diverse functions and clarification of the molecular mechanisms that generate them

Principal Investigator

Project Period (FY)

Research Category

Research Field

BABA Hiroko 馬場広子