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YAMADA Michiyuki  山田 道之

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… Alternative Names

YAMADA Michio  山田 道之

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Researcher Number 10076995
Other IDs
External Links
Affiliation (Current) 2025: 横浜市立大学, 生命医科学研究科, 客員教授
Affiliation (based on the past Project Information) *help 2003 – 2004: 横浜市立大学, 総合理学研究科, 教授
2000 – 2001: 横浜市立大学, 理学部, 教授
1995: 横浜市立大学, 理学部, 教授
1994: Yokohama City University Liberal Art and Science Professor
1993 – 1994: 横浜市立大学, 文理学部, 教授 … More
1992: 大阪大学, 蛋白質研究所, 助教授
1989 – 1992: 大阪大学, たんぱく質研究所, 助教授
1989 – 1990: 大阪大学, 蛋白質研究所, 助教授
1988: 大阪大学, 医学部・蛋白質研究所, 助教授
1986 – 1987: 大阪大学, 蛋白研究所, 助教授
1986 – 1987: 大阪大学, 蛋白質研究所, 助教授
1986: 阪大, 蛋白質研究所, 助教授
1985: 大阪大学, 蛋白研, 助教授 Less
Review Section/Research Field
Principal Investigator
代謝生物化学 / Functional biochemistry / Functional biochemistry
Except Principal Investigator
物質生物化学 / Pathological medical chemistry
Keywords
Principal Investigator
ミエロペルオキシダーゼ / 顆粒球 / 遺伝子発現 / Myeloperoxidase / 分化誘導 / 白血病細胞 / 転写調節 / 細胞分化 / レチノイン酸 / ミエロペルオキシダ-ゼ … More / monocytes / eosinophil / neutrophil / Citrullination / histone / peptidylarginine deiminase / Posttranslational modification / deimination / 単球 / 好酸球 / ヒストン / 好中球 / シトルリン化 / ペプチジルアルギニンデイミナーゼ / 翻訳後修飾 / 脱イミノ化 / cis-elements / Differentiation / Leukemia cells / Retinoic acid / Gene expression / Granulocytes / シス-エレメント / Cis-element of gene / Transfection of Recombinant Plasmid / Regulation of Gene Expression / 転写調節領域 / 遺伝子導入 / 遺伝子発現の調節 / ミエロトペルオキシダ-ゼ / ヒト白血病細胞 / mRNAの含量 / cDNAのクローニング / モノクローナル抗体 / 転写因子 / DNA結合タンパク質 / DNAメチル化 / DNaseI高感受性部位 … More
Except Principal Investigator
リソソーム / β-グルコシダーゼ / グルコセレブロシダーゼ / 癌遺伝子 / 血液幹細胞 / 選別輸送 / cDNA / ミエロペルオキシダーゼ / Acetyltransferase / Post-translational modification / Methionine aminopeptidase / Acetylation / Processing / 開始メチオニン / メチオニンアミノペプチダ-ゼ / アセチルトランスフェラ-ゼ / アセチル化 / プロセシング / (蛋白質)翻訳後修飾 / Acylamino acid releasing-enzyme / ミリスチル化 / アシルアミノ酸遊離酵素 / oxidative stress / alkaline phosphatase / proteasome / Rpn 9 / PCR-select subtraction / HL 60 / nitric oxide / hydrogen peroxide / サブトラクション法 / 抗酸化ストレス遺伝子 / NO耐性 / 差次的クローニング / HL60細胞 / 過酸化水素耐性 / 酸化ストレス / アルカリホスファターゼ / プロテアソーム / Rpn9 / PCRサブトラクション / HL60 / 一酸化窒素 / 過酸化水素 / フレンド白血病 / myc遺伝子 / WW^vマウス / PCR / トランスジェニックマウス / 白血病株細胞 / 造血因子遺伝子 / 前白血病状態 / 大顆粒リンパ球 / 多分化能幹細胞 / 自己再生産能力 / モザイクマウス / 細胞分化 / 細胞増殖 / 細胞培養 / 突然変異マウス / 増殖因子 / 結合蛋白質 / 偽遺伝子 / 偽遺伝子発現 / 貧血マウス / 松果体 / がん遺伝子 / フレンドウイルス / クローン性増殖 / 白血病 / 造血幹細胞 Less
  • Research Projects

    (18 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (19 People)
  •  Modification of histones by peptidylarginine deiminase and its biological significancePrincipal Investigator

    • Principal Investigator
      YAMADA Michiyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yokohama City University
  •  Cloning of novel anti-oxidative-stress genes form hydrogen peroxide-and nitric oxide-resistant cells

    • Principal Investigator
      NISHIKIMI Morirnitsu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Wakayama Medical University
  •  顆粒球分化における転写因子の役割Principal Investigator

    • Principal Investigator
      山田 道之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Yokohama City University
  •  マンノース6-燐酸非依存性のリソソーム酵素の識別機構

    • Principal Investigator
      今井 勝行
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Shimane Medical University
  •  マンノース6-リン酸非依存性のリソソーム酵素の識別機構

    • Principal Investigator
      今井 勝行
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Shimane Medical University
  •  Gene Expression of Myeloperoxidase during Granulocyte DifferentiationPrincipal Investigator

    • Principal Investigator
      YAMADA Michiyuki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yokohama City University
  •  マンノース6-リン酸非依存性のリソソーム酵素の識別機構

    • Principal Investigator
      今井 勝行
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Shimane Medical University
  •  顆粒球の発生の初期に特異的なミエロペルオキシダ-ゼの発現機構Principal Investigator

    • Principal Investigator
      山田 道之
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  顆粒球の発生の初期に特異的なミエロペルオキシダーゼの発現機構Principal Investigator

    • Principal Investigator
      山田 道之
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  造血幹細胞の不死化・白血病化によるクローン性増殖発展の制御機構

    • Principal Investigator
      三浦 恭定
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Jichi Medical University
  •  Regulation of Myeloperoxidase Gene Expression in Polymorphonuclear LeukocytesPrincipal Investigator

    • Principal Investigator
      YAMADA Michiyuki
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Osaka University
  •  造血幹細胞の不死化・白血病化によるクローン性増殖発展の制御機構

    • Principal Investigator
      三浦 恭定
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Jichi Medical University
  •  Role of the Processing at Amino-Terminus on the Regulation of Half-life of Protein

    • Principal Investigator
      TSUNASAWA Susumu
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  血液幹細胞のクローン性増殖から白血病への進展

    • Principal Investigator
      北村 幸彦
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  血液幹細胞のクローン性増殖から白血病への進展

    • Principal Investigator
      北村 幸彦
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  HL-60細胞におけるミエロペルオキシダーゼmRNAの生合成と制御機構Principal Investigator

    • Principal Investigator
      山田 道之
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Osaka University
  •  Bilogical Roles on N-Acylamino Acid Releasing-enzyme-especially on the protein myristylation-

    • Principal Investigator
      TSUNASAWA Susumu
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Osaka University
  •  ヒトミエロペルオキシダーゼのモノクローナル抗体の作製と白血病の診断への利用Principal Investigator

    • Principal Investigator
      山田 道之
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University

All 2004 2003 Other

All Journal Article

  • [Journal Article] Structual basis for Ca^<2+>-induced activation of human PAD42004

    • Author(s)
      Arita K, Hashimoto H, Shimizu T, Nakashima K, Yamada M, Sato M
    • Journal Title

      Nature SMB 11

      Pages: 777-783

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570122
  • [Journal Article] Structual basis for Ca^<2+>-induced activation of human PAD42004

    • Author(s)
      Arita, K., Hashimoto, H., Shimizu, T., Nakashima, K., Yamada, M., Sato, M.
    • Journal Title

      Nature SMB 11

      Pages: 777-783

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570122
  • [Journal Article] Histone Deimination Antagonizes Arginine methylation2004

    • Author(s)
      Cuthbert GL, Daujat S, Snowden AW, Erdjument-Bromage H, Hagiwara T, Yamada M, Schneider R, Gregory PD, Tempst P, Bannister AJ, Kouzarides T
    • Journal Title

      Cell 118

      Pages: 545-553

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570122
  • [Journal Article] Histone Deimination Antagonizes Arginine methylation2004

    • Author(s)
      Cuthbert, G.L., Daujat, S., Snowden, A.W., Erdjument-Bromage, H., Hagiwara, T., Yamada, M,.Schneider, R., Gregory, P.D., Tempst, P., Bannister, A.J., Kouzarides, T.
    • Journal Title

      Cell 118

      Pages: 545-553

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570122
  • [Journal Article] Crystallization and preliminary X-ray crystallographic analysis of human peptidylarginine deiminase V2003

    • Author(s)
      Arita, K., Hashimoto, H., Shimizu, T., Yamada, M., Sato, M.
    • Journal Title

      Acta Cryst. D 59

      Pages: 2332-2333

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570122
  • [Journal Article] Crystallization and preliminary X-ray crystallographic analysis of human peptidylarginine deiminase V2003

    • Author(s)
      Arita K, Hashimoto H, Shimizu T, Yamada M, Sato M
    • Journal Title

      Acta Cryst.D 59

      Pages: 2332-2333

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570122
  • [Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes

    • Author(s)
      Hagiwara, T., Hidaka, Y., Yamada, M.
    • Journal Title

      Biochemistry (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570122
  • [Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes

    • Author(s)
      Hagiwara T, Hidaka Y, Yamada M
    • Journal Title

      Biochemistry (in press)

    • Data Source
      KAKENHI-PROJECT-15570122
  • [Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes

    • Author(s)
      Hagiwara T, Hidaka Y, Yamada M
    • Journal Title

      Biochemistry (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570122
  • 1.  高久 史磨 (40048955)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  北村 幸彦 (70028520)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  今井 勝行 (60035425)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  辻 省次 (70150612)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  TSUNASAWA Susumu (30029962)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  三浦 恭定 (60048965)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  井上 達 (50100110)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  井川 洋二 (40085618)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  森 和博 (90025635)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  須田 年生 (60118453)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  田ノ岡 宏 (90076969)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  NISHIKIMI Morirnitsu (20022816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  INAI Yoko (20316087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  BULGAC Ellena
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  STERNGLANZ Rolf
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MOERSCHELL Richard
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  DUMONT Mark
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SHERMAN Fred
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KATO Ikunoshin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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