YOKOYAMA Yuusaku 横山祐作

Researcher Number	10095325
Other IDs
External Links
Affiliation (Current)	2020: 東邦大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2008 – 2010: Toho University, 薬学部, 教授 2007: Toho University, Faculty of Pharmaceutical Sciences, Associate Professor 2005 – 2006: 東邦大学, 薬学部, 助教授 2000 – 2003: 東邦大学, 薬学部, 助教授 1996 – 1998: 東邦大学, 薬学部, 助教授 1988 – 1994: 東邦大学, 薬学部, 助教授 1993: 東邦大学, 薬学部・助教授, 助教授
Review Section/Research Field	Principal Investigator Chemical pharmacy / Chemical pharmacy Except Principal Investigator Chemical pharmacy
Keywords	Principal Investigator トリプトファン / 水溶液 / パラジウム / リゼルギン酸 / 光学活性 / 有機合成 / 無保護アミノ酸 / 脱炭酸 / アミノアルコール / N-メチルアミノ酸 … More Except Principal Investigator インドール / オルト置換ジアシルアニリン / N-C軸不斉 / 光学活性 / イミド / ラセミ化 / 不斉アシル化 / 化学選択的アシル化 / ねじれ / オルト置換アニリン / オルトトリフルオロメチルアニリン / N-アセチル化 / N-アシル化 / N,N-ジアセチルアニリン / トランス-アセチル化 / ピロール / アルカロイド / 位置特異的 / アシル化 / ブロム化 / ハイメニン / 脱ブロム化 / カルボリンアルカロイド / ウィティッヒ反応 / ベックマン転位 / ピロ-ル / インド-ル / Pyrrole / Indole / Alkaloid / Regiospecific / Acylation / Bromination / Hymenin / カンチン-6-オン / リゼルグ酸 / Reissertインドール合成 / ベンズトリプトファン / アシルインドール / アルキルインドール / Heck反応 / ベンズインドール / 閉環反応 / β-カルボリン / リゼルギン酸 / キノロン / バッカクアルカロイド / DMAT / ene-diamine / N-acylation / スルホンアミド / canthine-6-one / indole / lysergic acid / Reissert indole synthesis / benztryptophan / acylindole / alkylindole / Heck reaction Less

Reaction of unprotected amino acids with aldehydes : New synthetic method for stereoselective 1,2-aminoalchol.Principal Investigator
- Principal Investigator
  
  YOKOYAMA Yuusaku
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
Synthetic Reaction in Aqueous Media U sing Unprotected Amino Acid as a Starting MaterialPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Yuusaku
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
Study of the Reaction of Unprotected Amino Acids in Aqueous Media and its Application for the Short-Step Synthesis of Ergot AlkaloidsPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Yuusaku
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
Development of New Reactivities of Indole Nucleus and its Application to Syntheses of Natural Products
- Principal Investigator
  
  MURAKAMI Yasuoki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
オルト置換アニリンのN,N-ジアセチル化その立体化学への応用
- Principal Investigator
  
  MURAKAMI Yasuoki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
Synthesis of Optically Active Lysergic AcidPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Yuusaku
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
New Synthetic Method for Polyalkyl-Substituted Aromatic Bromides using Palladium and its ApplicationPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Yuusaku
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  TOHO UNIVERSITY
Synthetic Study of Naturally Occurring Indoles Possessing Various Substituents on Benzene Moiety.
- Principal Investigator
  
  MURAKAMI Yasuoki
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  TOHO UNIVERSITY
Palladium Catalyzed Direct Allylation of Aromatic Bromides and its Application.Principal Investigator
- Principal Investigator
  
  YOKOYAMA Yuusaku
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University

All 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Patent

[Journal Article] Development of an ELISA system to determine the presence of antibodies specific fortaxane structures2011
- Author(s)
  Satoshi Muto, Yuichi Kouyama, Yuusaku Yokoyama, Hiroaki Okuno, Toshihiro Ishii, Toru Masak, Yasuo Matsuzawa, Tatsuo Kawashima, Koji Shiraie
- Journal Title
  
  Biol.Parm.Bull. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590014
[Journal Article] Palladium-Catalyzed mono-N-Allylation of Unprotected Amino Acids with 1,1-Dimethylallyl Alcohol in Water2011
- Author(s)
  Hidemasa Hikawa, Yuusaku Yokoyama
- Journal Title
  
  Org.Biomol.Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590014
[Journal Article] Cross-coupling reaction on N-(3,5-dibromo-2-pyridyl)piperazines : regioselective synthesis of 3,5-disubstituted pyridylpiperazines2010
- Author(s)
  Hikawa Hidemasa ; Yokoyama Yuusaku
- Journal Title
  
  Tetrahedron 66(49)
  
  Pages: 9552-9559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590014
[Journal Article] Mechanism for the direct synthesis of tryptophan from indole and serine: a useful NMR technique for the detection of a reactive intermediate in the reaction mixture2010
- Author(s)
  Yokoyama Yuusaku ; Nakakoshi Masamichi ; Okuno Hiroaki ; Sakamoto Yohko ; Sakurai Satoshi
- Journal Title
  
  Magnetic Resonance in Chemistry 48(10)
  
  Pages: 811-817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590014
[Journal Article] Mechanism for the direct synthesis of tryptophan from indole and serine : a useful NMR technique for the detection of a reactive intermediate in the reaction mixture2010
- Author(s)
  Yuusaku Yokoyama
- Journal Title
  
  Magnetic Resonance in Chemistry
  
  Volume: 80 Pages: 455-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590014
[Journal Article] Synthesis and evaluation of a novel liposome containing BPA-peptide conjugate for BNCT2009
- Author(s)
  Shirakawa Makoto ; Yamamto Tetsuya ; Nakai Kei ; Aburai Kenichi ; Kawatobi Sho ; Tsurubuchi Takao ; Yamamoto Yohei ; Yokoyama Yuusaku ; Okuno Hiroaki ; Matsumura Akira
- Journal Title
  
  Applied Radiation and Isotopes 67(7-8S)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590014
[Journal Article] Chemoselective palladium-catalyzed reaction in aqueous media : Selectivity in the reaction of haloanilines with 1,1-dimethylallyl alcohol2007
- Author(s)
  Yuusaku Yokoyama
- Journal Title
  
  Advanced Synthesis and Catalysis 349
  
  Pages: 662-668
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] Chemoselective palladium-catalyzed reaction in aqueous media : Selectivity in the reaction of haloanilines with 1,1-dimethylallyl alcohol2007
- Author(s)
  Yokoyama, Y., Takagi, T., Hikawa, H., Kaneko, S., Tsubaki, N., Okuno, H
- Journal Title
  
  Advanced Synthesis & Catalysis 349
  
  Pages: 662-668
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] Chemoselective palladium-catalyzed reaction in aqueous media:Selectivity in the reaction of haloanilines with 1,1-dimethylallyl alcohol2007
- Author(s)
  Yuusaku Yokoyama
- Journal Title
  
  Advanced Synthesis and Catalysis 349
  
  Pages: 662-668
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] Devolopment of Aggregation inhibitors for amyloid-J3 peptides and their evaluation by quarts-crystal microbalance2007
- Author(s)
  Okuno, H., Mori, K., Okada, T., Yokoyama, Y., Suzuki, H
- Journal Title
  
  Chem. Bia Drug Des 69
  
  Pages: 356-361
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] Synthesis and evaluation of a novel lipid-peptide conjugate for functionalized liposome2007
- Author(s)
  Yagi, N., Yano, Y., Hatanaka, K., Yokoyama, Y., Okuno, H
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 17
  
  Pages: 2590-2593
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] Chemistry of Unprotected Amino Acids in Aqueous Solution : Direct Bromination of Aromatic Amino Acids with Bromoisocyanuric acid Sodium Salt under Strong Acidic Condition2006
- Author(s)
  Yokoyama, Y, Yamaguchi, T, Sato, M, Kobayashi, E, Murakami, Y, Okuno, H
- Journal Title
  
  Chem. Pharm. Bull 54
  
  Pages: 1715-1719
- NAID
  110004863645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] An improved synthesis of optically pureR-4-bromo-N-methyl-1-tosyltryptophan derivative, a key intermediate in the synthesis of ergot alkaloids.2006
- Author(s)
  Yuusaku Yokoyama
- Journal Title
  
  Chemcal and Pharmaceutical Bulletin 54(12)
  
  Pages: 1715-1719
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] Chemistry of Unprotected Amino Acids in Aqueous Solution:Direct Bromination of Aromatic Amino Acids with Bromoisocyanuric acid Sodium Salt under Strong Acidic Condition2006
- Author(s)
  Yuusaku Yokoyama
- Journal Title
  
  Chemcal and Pharmaceutical Bulletin 54(12)
  
  Pages: 1715-1719
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] An Improved Synthesis of Optically Pure (R)-4-Bromo-N-methyl-1-tosyltryptophan Derivative, A Key Intermediate in the Synthesis of Ergot Alkaloids.2005
- Author(s)
  Yuusaku Yokoyama
- Journal Title
  
  Heterocycles 65
  
  Pages: 1455-1459
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] An improved synthesis of optically pure (R)-4-bromo-N-methyl-1-tosyltryptophan derivative, a key intermediate in the synthesis of ergot alkaloids2005
- Author(s)
  Yokoyama, Y, Hara, R, Kato, N, Murakami, Y, Okuno, H
- Journal Title
  
  Heterocycles 2005
  
  Pages: 1455-1459
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Journal Article] An Improved Synthesis of Optically Pure(R)-4-Bromo-N-methyl-1-tosyltryp tophan Derivative,A Key Intermediate in the Synthesis of Ergot Alkaloids2005
- Author(s)
  Yuusaku Yokoyama
- Journal Title
  
  Heterocycles 65
  
  Pages: 1455-1459
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590016
[Patent] トリプトファン誘導体、その製造方法及びそれを有効成分とするインドールアミン酸素添加酵素阻害剤2007
- Inventor(s)
  滝川修、秋元秀俊、奥野洋明、横山祐作
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Industrial Property Number
  2007-041962
- Filing Date
  2007-02-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Patent] 特許権2007
- Inventor(s)
  滝川修, 秋元秀俊, 奥野洋明, 横山祐作
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興財団
- Industrial Property Number
  2007-041962
- Filing Date
  2007-02-22
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] 水溶液中でのアシル化反応:反応条件の検討2010
- Author(s)
  藤岡秀輔,前田梨紗,氷川英正,横山祐作
- Organizer
  日本薬学会第129年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 3,5-ジ置換ピリジルピペラジン誘導体の位置選択的な合成2010
- Author(s)
  氷川英正、横山祐作
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 無保護アミノ酸の反応:赤堀反応の展開2010
- Author(s)
  横山祐作
- Organizer
  第36回反応と合成の進歩シンポジウム
- Place of Presentation
  ウインクあいち(愛知県)
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 水溶液中でのアシル化反応(Part II)2010
- Author(s)
  藤岡秀輔,氷川英正,横山祐作
- Organizer
  日本薬学会関東支部大会
- Place of Presentation
  八王子
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] アミノ酸の脱炭酸-アルドール反応を用いたシネフリン及びフェニレフリン塩酸塩の合成法の開発2010
- Author(s)
  熊谷修一,松田直也,氷川英正,横山祐作
- Organizer
  日本薬学会第129年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] バイオ医薬品開発に有用な親水性リンカーの合成研究2010
- Author(s)
  松田卓也、氷川英正、八木信宏、横山祐作
- Organizer
  日本薬学会関東支部大会
- Place of Presentation
  八王子
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] インドールとセリンの反応によるトリプトファン不斉合成への試み2010
- Author(s)
  瀬下麻衣子、横山祐作、中越雅道
- Organizer
  日本薬学会関東支部大会
- Place of Presentation
  八王子
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] バイオ医薬品開発に有用な親水性ポリマーの合成研究2010
- Author(s)
  松田卓也,氷川英正,八木信宏,横山祐作
- Organizer
  日本薬学会第129年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 無保護アミノ酸の反応:赤堀反応の展開2010
- Author(s)
  横山祐作、氷川英正、松田直也、熊谷修一
- Organizer
  第36回反応と合成のシンポジウム-ライフサイエンスを試行した理論、反応および合成-
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Esterification of Water Soluble Alcohols in Homogeneous Aqueous Solution2009
- Author(s)
  横山祐作
- Organizer
  7^<th> AFMC International Medicinal Chemistry Symposiumu(AIMECS09)
- Place of Presentation
  The Cairns Convention Center, Queensland Australia
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Mechanistic Consideration for the Synthesis of Tryptophan from Indole and Serine Based on NMR Spectra.2009
- Author(s)
  Yuusaku Yokoyama, Masamichi Nakakoshi, Hiroaki Okuno, Yoko Sakamoto, Satoshi Sakurai
- Organizer
  The Paul A. Grieco Symposium
- Place of Presentation
  Montana, USA
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Mechanistic Consideration for the Synthesis of Tryptophan from Indole and Serine Based on NMR Spectra2009
- Author(s)
  横山祐作
- Organizer
  12^<th> Meeting of the International Society for Tryptophan Research(ISTRY)
- Place of Presentation
  Florence Polo Didattiodi Viale Morgagni(Italy)
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 無保護アミノ酸、糖を用いた新しい合成反応の開発2009
- Author(s)
  横山祐作
- Organizer
  文部科学省戦略的基盤形成支援事業有機合成と天然物化学の手法による医薬品素材の開発第3回研究発表会
- Place of Presentation
  徳島文理大学薬学部
- Year and Date
  2009-12-19
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Esterification of Water Soluble Alcohols in Homogeneous Aqueous Solution2009
- Author(s)
  横山祐作
- Organizer
  The 6^<th> Joint Seminar on Biomedicinal Science among Prince of Songla University(PSU), Chiang Mai University(CMU), Kunming Medical University(KMU), and Toho University
- Place of Presentation
  Grand Prince Hotel New Takanawa Conference Hall(Tokyo)
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Mechanistic Consideration for the Synthesis of Tryptophan from Indole and Serine Based on NMR SPECTRA2009
- Author(s)
  横山祐作
- Organizer
  The Paul A.Grieco Symposium
- Place of Presentation
  Montana State University, USA
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Esterification of Water Soluble Alcohols in Homogeneous Aqueous Solution2009
- Author(s)
  横山祐作
- Organizer
  The Paul A.Grieco Symposium
- Place of Presentation
  Montana State University, USA
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Esterification of Polyols in Water (Part II)2009
- Author(s)
  Yuusaku Yokoyama, Risa Maeda, Hidemasa Hikawa, Hiroaki Okuno, Shusuke Fujioka
- Organizer
  日本プロセス学会 2009 サマーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Mechanistic consideration for the synthesis of tryptophan from indole and serine based on nmr spectra2009
- Author(s)
  Yuusaku Yokoyama, Masamichi Nakakoshi, Hiroaki Okuno, Yohko Sakamoto, Satoshi Sakurai
- Organizer
  12th Meeting of the International Society for Tryptophan Research (ISTRY)
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 水中でのポリオールのエステル化反応2009
- Author(s)
  氷川英正、藤岡秀輔、前田梨紗、奥野洋明、横山祐作
- Organizer
  第35回反応と合成の進歩シンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Esterification of Water Soluble Alcohols in Homogeneous Aqueous Solution2009
- Author(s)
  Yuusaku Yokoyama, Risa Maeda, Hiroaki Okuno
- Organizer
  The Paul A. Grieco Symposium
- Place of Presentation
  Montana, USA
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Indolamine 2,3-Dioxygenase(IDO)の新規阻害剤開発の新展開2009
- Author(s)
  横山祐作
- Organizer
  日本トリプトファン研究会第31回学術集会
- Place of Presentation
  九州栄養福祉大学(北九州市)
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Esterification of Water Soluble Alcohols in Homogeneous Aqueous Solution2009
- Author(s)
  Yuusaku Yokoyama, Risa Maeda, Hiroaki Okuno
- Organizer
  7th AFMC International Medicinal Chemistry Congress (AIMECS09)
- Place of Presentation
  Cairns, Australia
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Synthesis and biological evaluation of indoleamine 2,3-dioxygenase (IDO) inhibitor2009
- Author(s)
  Takafumi Suzuki, Osamu Takikawa, Hiroaki Okuno, Yuusaku Yokoyama
- Organizer
  The 6th Joint Seminar on Biomedicinal Science among Prince of Songla University (PSU), Chiang Mai University (CMU), Kunming Medical University (KMU), and Toho University.
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 水中でのポリオールのエステル化反応(Part II)2009
- Author(s)
  横山祐作
- Organizer
  日本プロセス化学会 2009サマーシンポジウム
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 無保護アミノ酸、糖を用いた新しい合成反応の開発(文部科学省戦略的基盤形成支援有機合成と天然物化学の手法による医薬品素材の開発)2009
- Author(s)
  横山祐作
- Organizer
  第3回研究発表会
- Place of Presentation
  徳島市(招待講演)
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Synthesis and Inhibitory Activity of Indoleamine 2, 3-Dioxygenase2008
- Author(s)
  横山祐作
- Organizer
  Synthesis and Inhibitory Activity of Indoleamine 2, 3-Dioxygenase
- Place of Presentation
  神戸国際会議場, 神戸市
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Esterification of polyalcohol in water2008
- Author(s)
  Risa Maeda, Yuusaku Yokoyama, Hiroaki Okuno
- Organizer
  The First International Symposium on Process Chemistry (ISPC08)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Synthesis and Inhibitory Activity of Indoleamine 2, 3-Dioxygenase2008
- Author(s)
  Yuusaku Yokoyama, Katsuhiko Tsutsumi, Hidetoshi Akimoto, Osamu Takikawa, Hiroaki Okuno
- Organizer
  The Eighth China-Japan Joint Symposium on Drug Design and Development
- Place of Presentation
  Kobe Japan
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Indoleamine 2,3-Dioxygenase (IDO) 阻害剤の合成2008
- Author(s)
  鈴木貴文、堤勝彦、山口智之、横山祐作、滝川修、奥野洋明
- Organizer
  第12回生体触媒化学シンポジウム-生体触媒による物質変換-
- Place of Presentation
  千葉、船橋
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] NMRによるセリンと無水酢酸の反応の検討:インドールとセリンの反応によるトリプトファン生成のメカニズム2008
- Author(s)
  横山祐作
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Indoleamine 2,3-Dioxygenase(IDO)阻害剤の開発 Part22008
- Author(s)
  鈴木貴文,横山祐作,滝川修,奥野洋明
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] 多価アルコールの水溶液中のエステル化; Part32008
- Author(s)
  前田梨紗,横山祐作,奥野洋明
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] beta-カルボリン骨格を有する新規五環性化合物の合成と Indoleamine 2, 3-Dioxygenase(IDO)阻害活性2008
- Author(s)
  横山祐作
- Organizer
  日本トリプトファン研究会第30回学術集会
- Place of Presentation
  川崎医科大学倉敷市
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] アシラーゼを用いた光学活性トリプトファン合成法の開発と光学活性 Clavicipitic Acid の3行程全合成2008
- Author(s)
  横山祐作
- Organizer
  第12回生体触媒化学シンポジウム-生体触媒による物質変換-
- Place of Presentation
  東邦大学船橋市
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-20590014
[Presentation] Development of Inhibitors of Indoleamine 2,3-dioxygenase(IDO)2007
- Author(s)
  Yokoyama Yuusaku
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul,Turke
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] 保護アミノ酸の反応:赤堀反応 Part22007
- Author(s)
  横山祐作
- Organizer
  第33回反応と合成の進歩シンポジウム-ライフサイエンスを志向した理論、反応および合成-
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Development of Inhibitors of Indoleamine 2,3-dioxygenase(IDO)2007
- Author(s)
  Yokoyama Yuusaku
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Development of Inhibitors of Indoleamine 2,3-dioxygenase (IDO)2007
- Author(s)
  Yokoyama,Y., Tsutsumi, K., Akimoto,H., Takikawa, O., Okuno, H
- Organizer
  6th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Istanbul, Turkey
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Indoleamine 2,3-Dioxygenase(IDO)阻害剤の開発 Part22007
- Author(s)
  横山祐作
- Organizer
  第26回メディシナルケミストリーシンポジウム
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] β-カルボリン骨格を有する新規五環性化合物の合成とIndoleamine 2,3-Dioxygenase(IDO)阻害活性2007
- Author(s)
  横山祐作
- Organizer
  日本トリプトファン研究会第29回学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] 無保護アミノ酸とアルデヒドの反応:アミノアルコールの一行程合成2007
- Author(s)
  横山祐作
- Organizer
  日本プロセス化学会2007サマーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Chemoselective Palladium Catalyzed Reaction in Aqueous Media : Selectivity in the Reaction of Bromoanilines with Allylic Alcohol2006
- Author(s)
  Yokoyama, Y., Takagi, N., Tsubaki, N., Kaneko, N., Hikawa, H., Okuno, H
- Organizer
  The llth Korea-Japan Joint Symposium on Drug Design And Development
- Place of Presentation
  Jeju Island, Korea
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Chemoselective Palladium Catalyzed Reaction in Aqueous Media:Selectivity in the Reaction of Bromoanilines with Allylic Alcohol2006
- Author(s)
  Yuusaku Yokoyama
- Organizer
  The 11th Korea-Japan Joint Symposium on Drug Design and Development
- Place of Presentation
  Jeju Island,Korea
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Chemoselective Palladium Catalyzed Reaction in Aqueous Media : Selectivity in the Reaction of Bromoanilines with Allylic Alcohol2006
- Author(s)
  Yokoyama, Y., Takagi, N., Tsubaki, N., Kaneko, N., Hikawa, H., Oktino, H
- Organizer
  The Tenth International Conference on New Aspects of Organic Chemistry (IKCOC-10)
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Chemoselective Palladium Catalyzed Reaction in Aqueous Media:Selectivity in the Reaction of Bromoanilines with Allylic Alcohol2006
- Author(s)
  Yuusaku Yokoyama
- Organizer
  The Tenth International Conference on New Aspects of Organic Chemistry(IKCOC-10)
- Place of Presentation
  Kyoto,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Bromoisocyanuric Acid Sodium Salt as a Brominating Reagent for Aromatic Amino Acid under Strong Acidic Condition2005
- Author(s)
  Yokoyama Yuusaku
- Organizer
  20th International Congress of Heterocyclic Chemistry, Palermo, Italy
- Place of Presentation
  Palermo,Italy
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Chemistry of Unprotected Amino Acid in Aqueous Solution:Direct Bromination of Aromatic Amino Acids in Strong Acidic Aqueous Media with Bromoisocyanuric Acid Sodium Salt2005
- Author(s)
  Yokoyama Yuusaku
- Organizer
  The Seventh China-Japan Joint Symposium on Drug Design and Development
- Place of Presentation
  Tokushima,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Bromoisocyanuric Acid Sodium Salt as a Brominating Reagent for Aromatic Amino Acid under Strong Acidic Condition2005
- Author(s)
  Yokoyama, Y., Satou, M., Yamaguchi, T., Kobayashi, E., Okuno, H., Murakami, Y
- Organizer
  20th International Congress of Heterocyclic Chemistry
- Place of Presentation
  Palermo, Italy
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016
[Presentation] Chemistry of Unprotected Amino Acid in Aqueous Solution : Direct Bromination of Aromatic Amino Acids in Strong Acidic Aqueous Media with Bromoisocyanuric Acid Sodium Salt2005
- Author(s)
  Yokoyama, Y., Yamaguchi, T., Satou, M., Okuno, H
- Organizer
  The Seventh China-Japan Joint Symposium on Drug Design and Development, Tokushima
- Place of Presentation
  Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590016

1. TANI Masanobu (50057733)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. SUZUKI Hideharu (40187753)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MURAKAMI Yasuoki (20009179)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KONDO Kasuhiro (90277343)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. WATANABE Toshiko (40120323)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results

YOKOYAMA Yuusaku 横山 祐作

Research Projects

Research Products

Co-Researchers

Reaction of unprotected amino acids with aldehydes : New synthetic method for stereoselective 1,2-aminoalchol.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthetic Reaction in Aqueous Media U sing Unprotected Amino Acid as a Starting MaterialPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of the Reaction of Unprotected Amino Acids in Aqueous Media and its Application for the Short-Step Synthesis of Ergot AlkaloidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of New Reactivities of Indole Nucleus and its Application to Syntheses of Natural Products

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

オルト置換アニリンのN,N-ジアセチル化その立体化学への応用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis of Optically Active Lysergic AcidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New Synthetic Method for Polyalkyl-Substituted Aromatic Bromides using Palladium and its ApplicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthetic Study of Naturally Occurring Indoles Possessing Various Substituents on Benzene Moiety.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Palladium Catalyzed Direct Allylation of Aromatic Bromides and its Application.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Development of an ELISA system to determine the presence of antibodies specific fortaxane structures2011

Author(s)

Journal Title

Data Source

[Journal Article] Palladium-Catalyzed mono-N-Allylation of Unprotected Amino Acids with 1,1-Dimethylallyl Alcohol in Water2011

Author(s)

Journal Title

Data Source

[Journal Article] Cross-coupling reaction on N-(3,5-dibromo-2-pyridyl)piperazines : regioselective synthesis of 3,5-disubstituted pyridylpiperazines2010

Author(s)

Journal Title

Data Source

[Journal Article] Mechanism for the direct synthesis of tryptophan from indole and serine: a useful NMR technique for the detection of a reactive intermediate in the reaction mixture2010

Author(s)

Journal Title

Data Source

[Journal Article] Mechanism for the direct synthesis of tryptophan from indole and serine : a useful NMR technique for the detection of a reactive intermediate in the reaction mixture2010

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis and evaluation of a novel liposome containing BPA-peptide conjugate for BNCT2009

Author(s)

YOKOYAMA Yuusaku 横山祐作