Suzuki Hideharu 鈴木英治

… Alternative Names

Researcher Number	40187753
Other IDs
External Links
Affiliation (Current)	2020: 帝京平成大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2014: 帝京平成大学, 薬学部, 教授 2012 – 2013: 東邦大学, 薬学部, 准教授 2005 – 2007: 東邦大学, 薬学部, 講師 2000 – 2002: 東邦大学, 薬学部, 講師 1996 – 1998: 東邦大学, 薬学部, 助手 1988 – 1993: 東邦大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Drug development chemistry Except Principal Investigator Chemical pharmacy / Living organism molecular science
Keywords	Principal Investigator アルツハイマー / アミロイドベータ / 凝集阻害剤 / 繊維化阻害剤 / ベンゾフラン / グルコサミン酸 / 多価フェノール / 有機合成 / ホスホン酸 / 繊維化阻害 … More Except Principal Investigator … More

Development of amyloid beta aggregation inhibitor for therapeutics of Alzheimer diseasePrincipal Investigator
- Principal Investigator
  
  SUZUKI Hideharu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Teikyo Heisei University
  Toho University
Development of aggregation disrupters for amyloid proteins
- Principal Investigator
  
  OKUNO Hiroaki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Toho University
Development of New Reactivities of Indole Nucleus and its Application to Syntheses of Natural Products
- Principal Investigator
  
  MURAKAMI Yasuoki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
オルト置換アニリンのN,N-ジアセチル化その立体化学への応用
- Principal Investigator
  
  MURAKAMI Yasuoki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
Synthetic Study of Naturally Occurring Indoles Possessing Various Substituents on Benzene Moiety.
- Principal Investigator
  
  MURAKAMI Yasuoki
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  TOHO UNIVERSITY
Palladium Catalyzed Direct Allylation of Aromatic Bromides and its Application.
- Principal Investigator
  
  YOKOYAMA Yuusaku
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University

All 2014 2013 2012 2008 2007 2005 Other

All Journal Article Presentation Patent

[Journal Article] Benzoyl methyl phosphates as efficient reagents in the one- pot tandem approach for the synthesis of 2-phenylbenzimidazoles in water.2014
- Author(s)
  Hikawa, Hidemasa; Imani, Maki; Suzuki, Hideharu; Yokoyama, Yuusaku; Azumaya, Isao,
- Journal Title
  
  RSC Advances
  
  Volume: 4(8) Pages: 3768-3773
- DOI
  10.1039/c3ra46749j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors.2013
- Author(s)
  Tanaka, Minoru; Li, Xin; Hikawa, Hidemasa; Suzuki, Takafumi; Tsutsumi, Katsuhiko; Sato, Masashi; Takikawa, Osamu; Suzuki, Hideharu; Yokoyama, Yuusaku,
- Journal Title
  
  Bioorg Med Chem.
  
  Volume: 21(5) Pages: 1159-1165
- DOI
  10.1016/j.bmc.2012.12.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147, KAKENHI-PROJECT-24590397
[Journal Article] Chemoselective Benzylation of Unprotected Anthranilic Acids with Benzhydryl Alcohols by Water- Soluble Au(III) /TPPMS in Water.2013
- Author(s)
  Hikawa, Hidemasa; Suzuki, Hideharu; Yokoyama, Yuusaku; Azumaya, Isao,
- Journal Title
  
  Journal of Organic Chemistry
  
  Volume: 78(13) Pages: 6714-6720
- DOI
  10.1021/jo401064f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] Au(III) /TPPMS- Catalyzed Benzylation of Indoles with Benzylic Alcohols in Water.2013
- Author(s)
  Hikawa, Hidemasa; Suzuki, Hideharu; Azumaya, Isao,
- Journal Title
  
  Journal of Organic Chemistry (2013), 78(23), 12128-12135.
  
  Volume: 78(23) Pages: 12128-12135
- DOI
  10.1021/jo402151g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] A practical regioselective synthesis of alkylthio- or arylthioindoles without the use of smelly compounds such as thiols.2013
- Author(s)
  Hamashima, Toshihiko; Mori, Yoshiaki; Sawada, Kazunori; Kasahara, Yuko; Murayama, Daisuke; Kamei, Yuto; Okuno, Hiroaki; Yokoyama, Yuusaku; Suzuki, Hideharu,
- Journal Title
  
  Chemical & Pharmaceutical Bulletin (2013), 61(3), 292-303.
  
  Volume: 61(3) Pages: 292-303
- NAID
  130002460113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] N-Benzylation/Benzylic C-H Amidation Cascade by the (η3-Benzyl)palladium System in Aqueous Media: An Effective Pathway for the Direct Construction of 3-Phenyl-3,4-dihydro- (2H)-1,2,4-benzothiadiazine 1,1-Dioxides2013
- Author(s)
  Hikawa, Hidemasa; Matsuda, Naoya; Suzuki, Hideharu; Yokoyama, Yuusaku; Azumaya, Isao,
- Journal Title
  
  Adv. Synth. Catal.
  
  Volume: 355(11-12) Pages: 2308-2320
- DOI
  10.1002/adsc.201300317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147, KAKENHI-PROJECT-25460026
[Journal Article] A Practical Regioselective Synthesis of Alkylthio- or Arylthioindoles without the Use of Smelly Compounds Such as Thiols2013
- Author(s)
  Toshihiko Hamashima, Yoshiaki Mori, Kazunori Sawada, Yuko Kasahara, Daisuke Murayama, Yuto Kamei, Hiroaki Okuno, Yuusaku Yokoyama, Hideharu Suzuki
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 61 Issue: 3 Pages: 292-303
- DOI
  10.1248/cpb.c12-00882
- NAID
  130002460113
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] Synthesis of VIP- lipopeptide using a new linker to modify liposomes: towards the development of a drug delivery system for active targeting.2013
- Author(s)
  Masaka, Toru; Matsuda, Takuya; Li, Yingpeng; Koide, Yuki; Takami, Akira; Yano, Kenji; Imai, Ryosuke; Ichihara, Risa; Yagi, Nobuhiro; Suzuki, Hideharu;
- Journal Title
  
  Chemical & Pharmaceutical Bulletin (2013), 61(11), 1184-1187.
  
  Volume: 61(11) Pages: 1184-1187
- NAID
  130003360912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] Mechanistic studies for synthesis of bis(indolyl) methanes: pd- catalyzed C- H activation of indole- carboxylic acids with benzyl alcohols in water. Hikawa,2013
- Author(s)
  Hikawa, Hidemasa; Suzuki, Hideharu; Yokoyama, Yuusaku; Azumaya, Isao,
- Journal Title
  
  Catalysts (2013), 3(2), 486-500.
  
  Volume: 3(2) Pages: 486-500
- DOI
  10.3390/catal3020486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] SYNTHESIS AND EVALUATION OF 4-ARYL-2(1H)-QUINOLINONES AS POTENT AMYLOID β FIBRILLOGENESIS INHIBITORS2012
- Author(s)
  Yoko Shimokawa
- Journal Title
  
  Heterocycles
  
  Volume: 85 Pages: 1933-1940
- DOI
  10.3987/com-12-12506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590022, KAKENHI-PROJECT-24590147
[Journal Article] Development of a New Distyrylbenzene-Derivative Amyloid-β-aggregation and Fibril Formation Inhibitor2012
- Author(s)
  Hideharu Suzuki, Akihito Ishigami, Ayako Orimoto, Akihiro Matsuyama, Setsuko Handa, Naoki Maruyama, Yuusaku Yokoyama,a Hiroaki Okuno, and Masamichi Nakakoshi
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 60 Issue: 9 Pages: 1164-1170
- DOI
  10.1248/cpb.c12-00365
- NAID
  130001852537
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] Pd-Catalyzed Benzylic C－H Amidation with Benzyl Alcohols in Water: A Strategy To Construct Quinazolinones2012
- Author(s)
  Hidemasa Hikawa, Yukari Ino, Hideharu Suzuki, Yuusaku Yokoyama
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 77 Pages: 7046-7051
- DOI
  10.1021/jo301282n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590147
[Journal Article] Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance2007
- Author(s)
  Hiroaki Okuno, Kanae Mori, Tomoko Okada, Y. Yokoyama, H. Suzuki
- Journal Title
  
  Chemical Biology ＆ Drug Design (submitted)
- Data Source
  KAKENHI-PROJECT-17310132
[Journal Article] Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance2007
- Author(s)
  Okuno, Mori, Okada, Yokoyama and Suzuki
- Journal Title
  
  Chemical Biology & Drug Design 69
  
  Pages: 356-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17310132
[Journal Article] Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance2007
- Author(s)
  Okuno, Mori, Okada, Yokoyama, Suzuki
- Journal Title
  
  Chemical Biology&Drug Design 69
  
  Pages: 356-361
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17310132
[Journal Article] Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance2007
- Author(s)
  Hiroaki, Okuno, Kanae, Mori, Tomoko, Okada, Yuusaku, Yokoyama, Hideharu, Suzuki
- Journal Title
  
  Chemical Biology & Drug Design 69(5)
  
  Pages: 356-361
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17310132
[Journal Article] A Total Synthesis of 1-Methoxycanthin-6-one : An Efficient One-Pot Synthesis of the Canthin-6-one Skeleton from b-Carboline-1-carboxyaldehyde2005
- Author(s)
  Suzuki H, Adachi M, Ebihara Y, Gyoutoku H, Furuya H, Murakami Y, Okuno H
- Journal Title
  
  Synthesis
  
  Pages: 28-32
- Data Source
  KAKENHI-PROJECT-17310132
[Journal Article] A New Synthesis of 4-Oxygenated β-carboline Derivatives by Fischer Indolization2005
- Author(s)
  Suzuki, H., Tsukakoshi, Y., Tachikawa, T., Miura, Y., Adachi, M., Murakaimi Y.
- Journal Title
  
  Tetrahedron Letters
  
  Pages: 3831-3834
- Data Source
  KAKENHI-PROJECT-17310132
[Patent] アミロイドベータ凝集阻害作用を有するフェノール誘導体2008
- Inventor(s)
  奥野、鈴木、石神
- Industrial Property Rights Holder
  奥野、鈴木、石神、興和(株)
- Industrial Property Number
  2008-041928
- Filing Date
  2008-02-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17310132
[Patent] アミロイドベータ凝集阻害作用を有するフェノール誘導体2007
- Inventor(s)
  奥野洋明, 鈴木英治, 石神昭人
- Industrial Property Rights Holder
  奥野洋明, 鈴木英治, 石神昭人, 興和創薬
- Industrial Property Number
  2007-044155
- Filing Date
  2007-02-23
- Data Source
  KAKENHI-PROJECT-17310132
[Presentation] 水中でのAu(III)TPPMS触媒を用いたインドールのベンジル化反応
- Author(s)
  氷川英正、鈴木英治、東屋功
- Organizer
  第４０回反応と合成の進歩シンポジウム
- Place of Presentation
  東北大学川内萩ホール（宮城県仙台市）
- Year and Date
  2014-11-10 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] 水中でのPd触媒を用いたアニリンのベンジル化
- Author(s)
  泉京江、井野友加里、氷川英正、鈴木英治、横山祐作、東屋功
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] アルツハイマー病治療薬を目的としたアミロイドβ凝集阻害剤の開発：D-Gluco samic acidを親水性部位とするベンゾフラン誘導体の合成
- Author(s)
  角田まりえ、町野有望、丸山慧、田中晴希、中越雅道、津吹政可、氷川英正、鈴木英治、東屋功
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] 水中でのグリセリンとMBPの不斉アシル化反応の検討
- Author(s)
  深山翔太、氷川英正、鈴木英治、横山祐作
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] D-グルコサミンからFmoc固相合成に適したD-グルコサミン酸保護体の合成
- Author(s)
  丸山慧、田中晴希、小倉有季奈、松山明弘、氷川英正、横山祐作、鈴木英治
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] 水中でのπｰベンジルPdを用いたN-ベンジル化／ベンジル位C-Hアミド化連続反応
- Author(s)
  氷川英正、松田直也、鈴木英治、横山祐作、東屋功
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] グリセリンの不斉アシル化反応
- Author(s)
  内田有華、深山翔太、氷川英正、鈴木英治、横山祐作、東屋功
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] 新規Aβ凝集阻害剤の開発～2-フェニルベンゾフランのホスホン酸誘導体～
- Author(s)
  町野有望、丸山慧、田中晴希、柏田歩、中越雅道、津吹政可、氷川英正、鈴木英治、東屋功
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] アミロイドβ凝集阻害・繊維溶解作用をもつジアリルベンゾフラン誘導体
- Author(s)
  鈴木英治，矢島聖也，山口勇樹，佐々木雄大，中越雅道，石神昭人，津吹政可，横山祐作
- Organizer
  第30回メディシナルケミストリーシンポジウム
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] 紅藻ソゾノハナ由来の抗菌物質MC5-MC-8の全合成と抗菌活性
- Author(s)
  亀井勇統、濱島利彦、鈴木英治
- Organizer
  第２７回日本水産学会春季大会
- Place of Presentation
  東京海洋大学品川キャンパス（東京都港区）
- Year and Date
  2015-03-27 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] インドールを含む芳香族スルホンアミドの結晶構造中に見られる特徴的な分子間相互作用
- Author(s)
  前埜伊沙恵、片桐幸輔、氷川英正、鈴木英治、東屋功
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] Echinosulfone Aの全合成研究
- Author(s)
  村山大介、濱島利彦、池上蘭、森善昭、氷川英正、横山祐作、鈴木英治
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24590147
[Presentation] アントラセン骨格をもつボロン酸誘導体の結晶構造および蛍光特性
- Author(s)
  佐藤ひかり、枡飛雄真、氷川英正、鈴木英治、東屋功
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590147

1. TANI Masanobu (50057733)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. YOKOYAMA Yuusaku (10095325)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MURAKAMI Yasuoki (20009179)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KONDO Kasuhiro (90277343)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. WATANABE Toshiko (40120323)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ISHIGAMI Akihito (50270658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. OKUNO Hiroaki (20356710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 滝川修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 氷川英正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Hideharu 鈴木 英治

SUZUKI Hideharu 鈴木 英治

鈴木 英治 スズキ ヒデハル

Research Projects

Research Products

Co-Researchers

Development of amyloid beta aggregation inhibitor for therapeutics of Alzheimer diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of aggregation disrupters for amyloid proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of New Reactivities of Indole Nucleus and its Application to Syntheses of Natural Products

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

オルト置換アニリンのN,N-ジアセチル化その立体化学への応用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthetic Study of Naturally Occurring Indoles Possessing Various Substituents on Benzene Moiety.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Palladium Catalyzed Direct Allylation of Aromatic Bromides and its Application.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Benzoyl methyl phosphates as efficient reagents in the one- pot tandem approach for the synthesis of 2-phenylbenzimidazoles in water.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemoselective Benzylation of Unprotected Anthranilic Acids with Benzhydryl Alcohols by Water- Soluble Au(III) /TPPMS in Water.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Au(III) /TPPMS- Catalyzed Benzylation of Indoles with Benzylic Alcohols in Water.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A practical regioselective synthesis of alkylthio- or arylthioindoles without the use of smelly compounds such as thiols.2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] N-Benzylation/Benzylic C-H Amidation Cascade by the (η3-Benzyl)palladium System in Aqueous Media: An Effective Pathway for the Direct Construction of 3-Phenyl-3,4-dihydro- (2H)-1,2,4-benzothiadiazine 1,1-Dioxides2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Practical Regioselective Synthesis of Alkylthio- or Arylthioindoles without the Use of Smelly Compounds Such as Thiols2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

Suzuki Hideharu 鈴木英治

SUZUKI Hideharu 鈴木英治

鈴木英治スズキヒデハル

[Journal Article] Development of a New Distyrylbenzene-Derivative Amyloid-β-aggregation and Fibril Formation Inhibitor2012