MANNO Sumie 萬野純恵

… Alternative Names

萬野純恵マンノスミエ

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Researcher Number	10101205
External Links
Affiliation (based on the past Project Information) *help	2003 – 2015: 東京女子医科大学, 医学部, 講師 1999: 東京女子医大, 医学部, 講師 1998: 講師
Review Section/Research Field	Principal Investigator General medical chemistry Except Principal Investigator Biological Sciences / Parasitology (including Sanitary zoology) / General medical chemistry / Infectious disease medicine / General medical chemistry
Keywords	Principal Investigator ATP / 寿命 / ペントシジン / リボース / 糖化 / 変形能(膜伸展性) / スペクトリン / 赤血球 Except Principal Investigator 赤血球 / マラリア … More / バンド3蛋白質 / 赤血球変形能 / レクチン / マラリア原虫 / バンド3 / invasion / membrane property / asymmetric distribution / raft / membrane lipid / erythrocyte / malaria / 感染 / 膜機能 / 非対称分布 / ラフト / 膜脂質 / 非対称性分布 / リン脂質 / 抑制効果 / 多量体形成 / 赤血球膜 / スクランブリング抑制効果 / 赤血球寿命 / 溶血性貧血 / リン脂質輸送メカニズム / PLSCR1 / リン脂質スクランブリング / フリッパーゼ / スクランブラーゼ / コレステロール / ヒト赤血球膜 / Eat me signal / フォスファチジルセリン / リン脂質非対称性 / G蛋白質共役受容体 / シグナル伝達 / 感染症 / 抗感染症薬 / Feline immunodeficiency virus / Plasmodium falciparum / リドカイン / 脂質ラフト / 限定分解 / アンキリン / ATP / 反転膜小胞 / ホスファチジルセリン(PS) / 4.1タンパク質 / 自己蛍光相関蛍光法 / phospholipase / リン酸化 / Ca^<2+>-Calmodulin / 単一タンパク分子 / 自己相関蛍光測定法(FCS) / PSリポソーム / 4.1タンパク Less

An inhibitory effect of cholesterol on expressing eat me signals in human erythrocyte membrane
- Principal Investigator
  
  Takakuwa Yuichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Women's Medical University
Exploration of a novel role for lidocaine as a wide range spectrum anti-infection drug
- Principal Investigator
  
  TAKAKUWA Yuichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Tokyo Women's Medical University
An ATP-dependent mechanism protects spectrin against glycation in human erythrocytesPrincipal Investigator
- Principal Investigator
  
  MANNO Sumie
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Women's Medical University
Effect of erythrocyte membrane lipid dynamism on malaria invasion
- Principal Investigator
  
  TAKAKUWA Yuichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Tokyo Women's Medical University
マラリア原虫の侵入を許す赤血球(宿主細胞側)の必要・十分条件の解明/予防と治療の手がかりを探る
- Principal Investigator
  
  高桑雄一
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
マラリア原虫の侵入を許す赤血球(宿主細胞側)の必要・十分条件の解明
- Principal Investigator
  
  高桑雄一
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
単一分子によるタンパクと生体膜の結合解析:膜骨格タンパクと赤血球膜をモデルとして
- Principal Investigator
  
  TAKAKUWA Yuichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Women's Medical University

All 2013 2009 2008 2007 2005

All Journal Article Presentation

[Journal Article] Membrane peroxidation and methemoglobin formation are both necessary for band 3 clustering: mechanistic insights into human erythrocyte senescence2013
- Author(s)
  Arashiki Nobuto, Kimata Naoki, Manno Sumie, Mohandas Narla, Takakuwa Yuichi
- Journal Title
  
  Biochemistry
  
  Volume: 52 Issue: 34 Pages: 5760-5769
- DOI
  10.1021/bi400405p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659485, KAKENHI-PROJECT-25460375
[Journal Article] Functional evidence for presence of lipid rafts in erythrocyte membranes: Gsαin rafts is essential for signal transduction2008
- Author(s)
  Kamata K, Manno S, Ozaki M, Takakuwa Y
- Journal Title
  
  Am J Hematol
  
  Pages: 371-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590289
[Journal Article] Erythrocyte Shape Change Prevents Plasmodium falciparum Invasion Membrane2007
- Author(s)
  Boampong J N, Manno S, Koshino I, Takakuwa Y
- Journal Title
  
  32
  
  Pages: 95-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590289
[Journal Article] 翻訳後修飾による赤血球膜機能の調節2007
- Author(s)
  萬野純恵、高桑雄一
- Journal Title
  
  膜 32
  
  Pages: 122-128
- NAID
  130005077795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590289
[Journal Article] 翻訳後修飾による赤血球膜機能の調節膜2007
- Author(s)
  萬野純恵、高桑雄一
- Journal Title
  
  32
  
  Pages: 122-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590289
[Journal Article] 翻訳後修飾による赤血球膜機能の調節2007
- Author(s)
  萬野純恵, 他
- Journal Title
  
  膜 32
  
  Pages: 122-128
- NAID
  130005077795
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590408
[Journal Article] Erythrocyte Shape Change Prevents Plasmodium Falciparum Invasion2007
- Author(s)
  Boampong JN, Manno S, Koshino I, Takakuwa Y
- Journal Title
  
  Membrane 32
  
  Pages: 95-102
- NAID
  10018865838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590408
[Journal Article] Modulations occur in erythrocite membrane surface properties following malaria parasite invasion.2005
- Author(s)
  Aryee NA, Koshino T, Manno S, Takakuwa Y.
- Journal Title
  
  Membrane 30
  
  Pages: 157-164
- Data Source
  KAKENHI-PROJECT-16017296
[Journal Article] Modulation Occur in Erythrocyte Membrane Surface Properties Following Malaria Parasite Invasion2005
- Author(s)
  Aryee N.A., Koshino I., Manno S., Takakuwa Y.
- Journal Title
  
  Membrane 30・3(in press)
- Data Source
  KAKENHI-PROJECT-16017296
[Journal Article] Modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation.2005
- Author(s)
  Manno S, Takakuwa Y, Mohandas N.
- Journal Title
  
  J.Biol.Chem 280
  
  Pages: 7581-7487
- Data Source
  KAKENHI-PROJECT-16017296
[Journal Article] Modulation of Erythrocyte Membrane Mechanical Function by Protein 4.1 Phosphorylation2005
- Author(s)
  Manno S., Takakuwa Y., Mohandas N.
- Journal Title
  
  Journal of Biological Chemistry 280・9
  
  Pages: 7581-7587
- Data Source
  KAKENHI-PROJECT-16017296
[Presentation] 膜リン脂質非対称性の維持機構における膜コレステロールの役割2013
- Author(s)
  斎藤将樹、萬野純恵、高桑雄一
- Organizer
  日本膜学会第35年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] 脂質過酸化によってバンド3タンパク質に生じるメトヘモグロビンとの結合様式の変化のメカニズム2013
- Author(s)
  新敷信人、萬野純恵、高桑雄一
- Organizer
  日本膜学会第35年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] Phospholipid scramblase 1を介するリン脂質scramblingにおけるヒト赤血球膜コレステロールの抑制効果の検討2013
- Author(s)
  斎藤将樹、萬野純恵、高桑雄一
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] Phospholipid scramblase 1 (PLSCR1) を介したリン脂質のscrambling機構の検討2013
- Author(s)
  斎藤将樹、萬野純恵、高桑雄一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460375
[Presentation] 赤血球におけるSpectrinの糖化部位の解析と糖化防御機構の解明2009
- Author(s)
  萬野純恵、高桑雄一
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] The red cells have evolved an ATP-dependent protection mechanism against spectrin glycation2009
- Author(s)
  Manno S, Mohandas N, Takakuwa Y
- Organizer
  Gordon research conference
- Place of Presentation
  USA
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] 赤血球におけるSpectrinの糖化部位の解析と糖化防御機構の解明2009
- Author(s)
  萬野純恵、高桑雄一
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] The blood cells have evolved an ATP-dependent protective mechanism against spectrin glycation2009
- Author(s)
  Sumie MANNO
- Organizer
  Red Cells (Gordon Research Conferences 2009)
- Place of Presentation
  University of New England (USA)
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] 赤血球はATP濃度を維持することによりSpectrinの糖化を防ぐ機構を備えている2008
- Author(s)
  萬野純恵、高桑雄一
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] The red cells have evolved an ATP-dependent protection mechanism against spectrin glycation2008
- Author(s)
  Manno S, Takakuwa Y
- Organizer
  W. Mejbaum-Katzenellebogen's Molecular Biology Seminars
- Place of Presentation
  Zakopane
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] The Red Blood Cells Have Evolved an ATP-dependent Protective Machanism Against Spectrin Glycation2008
- Author(s)
  Sumie MANNO Yuichi TAKAKUWA
- Organizer
  European Membrane Skeleton Club (W. Mejbaum-Katzenellebogen's Molecular Biology Seminars)
- Place of Presentation
  Poland (Zakopane)
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] スペクトリンの糖化による赤血球膜機能2007
- Author(s)
  萬野純恵、高桑雄一
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] 赤血球膜機能の糖化による調節2007
- Author(s)
  萬野純恵、高桑雄一
- Organizer
  日本膜学会第29年会
- Place of Presentation
  東京
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-19590289
[Presentation] 赤血球膜機能の糖化による調節2007
- Author(s)
  萬野純恵、高桑雄一
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590289

1. TAKAKUWA Yuichi (40113740)

# of Collaborated Projects: 7 results

# of Collaborated Products: 23 results
2. KOSHINO Ichiro (80328377)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. TANAKA Shotaro (90380667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ARASHIKI Nobuto (80569658)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 小早川隆敏 (10072951)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SAITO Masaki (50400271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. NUNOMURA Wataru (70256478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 伊東栄子 (50119939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 金城政孝 (70177971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 加藤昌彦 (30349641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Mohandas Narla

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MANNO Sumie 萬野 純恵

萬野 純恵 マンノ スミエ

Research Projects

Research Products

Co-Researchers

An inhibitory effect of cholesterol on expressing eat me signals in human erythrocyte membrane

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of a novel role for lidocaine as a wide range spectrum anti-infection drug

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An ATP-dependent mechanism protects spectrin against glycation in human erythrocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of erythrocyte membrane lipid dynamism on malaria invasion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マラリア原虫の侵入を許す赤血球(宿主細胞側)の必要・十分条件の解明/予防と治療の手がかりを探る

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マラリア原虫の侵入を許す赤血球(宿主細胞側)の必要・十分条件の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

単一分子によるタンパクと生体膜の結合解析:膜骨格タンパクと赤血球膜をモデルとして

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Membrane peroxidation and methemoglobin formation are both necessary for band 3 clustering: mechanistic insights into human erythrocyte senescence2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional evidence for presence of lipid rafts in erythrocyte membranes: Gsαin rafts is essential for signal transduction2008

Author(s)

Journal Title

Data Source

[Journal Article] Erythrocyte Shape Change Prevents Plasmodium falciparum Invasion Membrane2007

Author(s)

Journal Title

Data Source

[Journal Article] 翻訳後修飾による赤血球膜機能の調節2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 翻訳後修飾による赤血球膜機能の調節膜2007

Author(s)

Journal Title

Data Source

[Journal Article] 翻訳後修飾による赤血球膜機能の調節2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Erythrocyte Shape Change Prevents Plasmodium Falciparum Invasion2007

Author(s)

Journal Title

NAID

Data Source

MANNO Sumie 萬野純恵

萬野純恵マンノスミエ