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OHKUMA Shoji
大熊 勝治
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Alternative Names
大態 勝治 オオクマ ショウジ
大熊 勝治 オオクマ シヨウジ
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Researcher Number
10119563
External Links
Affiliation (based on the past Project Information)
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2004 – 2005: 金沢大学, 自然科学研究科, 教授
2000 – 2003: Pharmaceutical Sciences, Kanazawa University Professor, 薬学部, 教授
2001: Kanazawa University Graduate School, Professor, 薬学部・分子細胞薬学, 教授
1998 – 2000: Graduate School of Kanazawa University, Professor, 大学院・自然科学研究科, 教授
1999: 金沢大学, 大学院・自然科学研究所, 教授
1991 – 1997: 金沢大学, 薬学部, 教授
1986 – 1987: 帝京大学, 薬学部, 助教授
Review Section/Research Field
Principal Investigator
Biological pharmacy
/
Cell biology
/
Biological Sciences
/
代謝生物化学
Except Principal Investigator
Biological pharmacy
/
Biological Sciences
/
Functional biochemistry
Keywords
Principal Investigator
PC12 / プロトンポンプ / ATPase / バフィロマイシン / アポトーシス / プロジギオシン / V-ATPase / プロトン・ポンプ / 再構成 / リソゾーム
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More
/ 膜融合 / GTP結合蛋白質 / 細胞分化 / コンカナマイシン / apoptosis / リソゾ-ム / cDNAクロ-ニング / ホスホリパーゼ / GTPγS / パフィロマイシン / H^+ / 突起伸展 / デストラキシン / bafilomycins / prodigiosins / cell-differentiation / concanamycins / 分化 / 癌 / Bafilomycin / Concanamycin / ペルオキシゾ-ム / クロフィブレ-ト / 単クロ-ン抗体 / イオン・チャンネル / パルオキシゾーム / クロフィプレート / ペルオキシゾーム / リソソーム / ペルオキシソーム / 神経突起 / 増殖阻害 / 塩化アンモニウム / 突起進展 / Cl^-シンポーター / PC12細胞 / 動脈硬化 / フォト・アフィニティー / ラット / 肝臓 / Lysosome / プロトン / ポンプ / H^+-ATPase / Triton-X-114 / C_<12>E_9 / bafilomycin / proton pump / neurite outgrowth / prodigiosin / cell differentiation / destruxin / 突起伸展(NOG) / nurite outgrowth (NOG) / CΓシンポーター / オートファジー / ドミナントネガティブ / 二次元電気泳動 / Cl^- / 二次元静電気泳動 / HeLa細胞 / CHO細胞 / neurite outgrowth (NOG) / V-ATpase / Affinity probe / 神経突起様突起伸長 / ネクローシス / 細胞増殖 / 細胞死 / プロトン輸送 / Affinity Probe / Neurite OutGrowth / Apoptosis / Necrosis / Cell Growth
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More
Except Principal Investigator
リソソーム / 膜融合 / Thermus / ペルオキシソーム / ATPase / タンパク輸送 / 基質能動輸送 / エネルギー共役 / オルガネラ / ラット / 肝臓 / リソソーム崩壊 / GTP結合蛋白質 / 塩基性薬物 / プトロン・ポンプ / グルココルチコイド核移行促進因子 / ホスホリパーゼA2 / N-エチルマレイミド / GTPγS / ウォルトマニン / ゴルジ体 / ゼブラフィッシュ / 初期発生 / 動脈硬化 / 過酸化脂質 / リポ蛋白 / 泡沫細胞 / 内皮細胞 / リポタン白質 / フルオレッセインデキストラン / 透過 / V-ATPase / T.thermophilus / ATP synthase
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Research Projects
(
21
results)
Co-Researchers
(
15
People)
Project Start Year (Newest)
Project Start Year (Oldest)
ゴルジ体が発生・分化に果たす役割の解析
Principal Investigator
中村 暢宏
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Kanazawa University
V-ATPase Inhibitor, pH and Cell Growth Inhibition
Principal Investigator
Principal Investigator
OHKUMA Shoji
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
V-ATPaseとがん治療
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
2001
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Kanazawa University
Study of mechanics
Principal Investigator
YOKOYAMA Ken
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
kanazawa University
V-ATPase阻害剤による新規制癌機構と治療戦略
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Kanazawa University
Control mechanisms of autophagy and apoptosis by a new group H^+/Cl^- symporting antibiotics
Principal Investigator
Principal Investigator
OHKUMA Shoji
Project Period (FY)
1999 – 2001
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
Search for cell-death inducing antitumor agents based on the anti-tumor activity of V-ATPase inhibitors
Principal Investigator
Principal Investigator
OHKUMA Shoji
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Biological pharmacy
Research Institution
Kanazawa University
リソソームのホモティピカルな膜融合機構の解析
Principal Investigator
新井 國三
Project Period (FY)
1997
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Biological pharmacy
Research Institution
Kanazawa University
Mechanism of induction of cell differentiation and cell death by inhibitors against V-ATPase
Principal Investigator
Principal Investigator
OHKUMA Shoji
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
空胞系プロトンポンプ阻害剤を用いたプロトン輸送機構と分化・細胞死誘導機構の解析
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
空胞系プロトンポンプ阻害剤による細胞分化誘導機構の解析
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cell biology
Research Institution
Kanazawa University
Endomembrane H^+-ATPaseと蛋白質輸送機構
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kanazawa University
ペルオキシソームATPaseの構造と機能
Principal Investigator
清水 栄
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
リソソームの崩壊機構とGTP結合蛋白質
Principal Investigator
荒井 國三
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
リソゾームの膜融合とペルオキシゾームのタンパク質輸送におけるATPaseの機能
Principal Investigator
Principal Investigator
大態 勝治
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kanazawa University
リソゾームとパルオキシゾームのタンパク質輸送に抱ける膜結合性ATPaseの機能
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kanazawa University
膜結合性ATPoseからみたリソゾ-ムとペルオキシゾ-ムの蛋白質輸送機構
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kanazawa University
リソゾ-ム膜上のH^±ATPaseと2種の新規ATPaseーその構造と機能に関する生化学的研究
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
培養血管内皮細胞を用いた物質輸送機構の解析
Principal Investigator
高野 達哉
Project Period (FY)
1987
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Teikyo University
Lysosome H^+-ATPaseの分子構築に関する生化学的・免疫化学的研究
Principal Investigator
Principal Investigator
大熊 勝治
Project Period (FY)
1987
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
代謝生物化学
Research Institution
Teikyo University
動脈硬化巣に蓄積する過酸化脂質とその意義
Principal Investigator
高野 達哉
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Teikyo University
# of Projects (Dsc)
# of Projects (Asc)
1.
ARAI Kunizo
(50126562)
# of Collaborated Projects:
14 results
# of Collaborated Products:
0 results
2.
清水 栄
(10110545)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
3.
YOKOYAMA Ken
(70271377)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
4.
木下 邦則
(20234320)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
5.
SOMEI Masanori
(20110546)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
6.
HATANAKA Yasumaru
(30111181)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
7.
OHTA Tetsuo
(09671290)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
8.
OHTA Tetsuo
(40194170)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
9.
高野 達哉
(40124995)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
10.
毛利 裕臣
(30182158)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
中村 暢宏
(50294955)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
酒井 則良
(50202081)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
峰尾 千恵子
(00190710)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
佐藤 隆一郎
(50187259)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
永井 和夫
(00011974)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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