YOKOYAMA Shinji 横山信治

… Alternative Names

YAKOYAMA Shinji

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Researcher Number	10142192
Other IDs
External Links
Affiliation (Current)	2025: 中部大学, 応用生物学部, 客員教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 中部大学, 応用生物学部, 客員教授 2018 – 2022: 中部大学, 生物機能開発研究所, 客員教授 2017: 中部大学, 生物機能開発研究所, 特任教授 2016: 中部大学, 応用生物学部, 特任教授 2011 – 2015: 中部大学, 応用生物学部, 教授 … More 2014: 中部大学, 次世代食育センター, 教授 2007 – 2010: 名古屋市立大学, 大学院・医学研究科, 教授 2006: Nagoya City University, Graduate School of Medical Sciences, Professor, 大学院医学研究科, 教授 2002 – 2005: 名古屋市立大学, 大学院・医学研究科, 教授 1997 – 2001: 名古屋市立大学, 医学部, 教授 1990 – 1994: アルバータ大学, 医学部, 教授 1989: NCVC, Dept. Etiology/Pathogenesis, Chief 1986 – 1987: 国立循環器病センター, 研究所・病因部, 室長 1986: National Cardiovascular Center Research Institute, その他, 研究員 Less
Review Section/Research Field	Principal Investigator Metabolomics / General medical chemistry / Biological Sciences / Basic Section 59040:Nutrition science and health science-related / Eating habits / 代謝生物化学 / 内分泌・代謝学 / Integrated Nutrition Science Except Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related … More / Metabolomics / Neurology / Biological Sciences / Basic Section 54040:Metabolism and endocrinology-related / Eating habits / 内分泌・代謝学 / Neurology Less
Keywords	Principal Investigator HDL / コレステロール / アポリポタンパク質 / 動脈硬化 / リポタンパク質 / ABCA1 / 脂質 / lipoprotein / アポリポ蛋白質 / Apolipoprotein … More / Cholesterol / 細胞 / cholesterol / apoA-I / Atherosclerosis / apolipoprotein / リポ蛋白質 / Signal Transduction / Cell / 動脈硬化症 / アストロサイト / sdLDL / 栄養摂取変動 / LDL / lipoproteins / 食品摂取 / 血漿リポタンパク質 / HDL-C / 魚介類／肉類比率 / 魚介類の摂取 / 肉類の摂取 / 疫学 / 生活環境 / probucol / apoA-II / ステロール代謝 / 栄養因子 / 栄養学的制御 / lipid transfer protein / cholesteryl ester transfer reaction / cholesteryl ester / 脂質転送タンパク質 / コレステリルエステル転送反応 / コレステリルエステル / Astrocyte / Brain / 脳 / アポリポ蛋白 / cell membrane / カペオリン / 細胞膜 / phosphlipid / 燐脂質 / calpain / nutritional sicences / atherosclrosis / 痴呆 / 脳神経疾患 / 生体分子 / 神経科学 / 脳障害修復 / アポE … More Except Principal Investigator HDL / ABCA1 / コレステロール / cholesterol / ABCA7 / アストロサイト / apoE / アポリポタンパク質 / Probucol / apolipoprotein / FGF-1 / オートクリン / active ingredient / anti-atherogenic / PMF / Cholesterol / astrocyte / apoAI / Pyrene Compound / Lipid Microemulsion / Discoidal Highdensity Plasma Lipoprotein / Apolipoprotein / Cholesterol Reverse Transport System / 脂質人工粒子 / ピレン-標識脂質 / 脂質転送蛋白質 / ディスコイダルHDL / コレステロール逆転送系 / マクロファージ / 血漿リポ蛋白 / リポ蛋白リパーゼ / SR-BI / acidicFGF / AMPK / PUFA / apoA-I / NCI-H295 / BLT-1 / 遊離コレステロール / 機能性栄養分子 / ノビレチン / タンゲレチン / functional ingredient / 炎症 / 脂質栄養 / HDLコレステロール / オキシステロール / ABCタンパク質 / AGE / 高血糖 / HDL代謝 / Atherosclerosis / Familial hypercholesterolemia / Lipoprotein lipase / Apolipoprotein E / LDL receptor / Hyperlipidemia / Plasma lipoprotein / 虚血性心疾患 / 家族性高コレステロール血症 / 動脈硬化 / アポリポ蛋白E5とE7 / 低密度リポ蛋白レセプター(LDLレセプター) / 家族性高コンステロール血症 / 粥状動脈硬化 / リポタンパク質リパ-ゼ / 〓状動脈硬化 / コレステロ-ル / 家族性高コレステロ-ル血症 / リポタンパク質リバ-ゼ / アポリポタンパク質E / LDLレセプタ- / 高脂血症 / 血漿リポタンパク質 / Stress / Astrocyte / プロブコール / ストレス / mouse primary hepatocytes / HepG2 cell / monoclonal antibody / hepatocytes / HDL generation / apolipoprotein AI / 725-1E / autocrine / Hepatocyte / マウス肝初代培養細胞 / HepG2 / モノクローナル抗体 / 肝細胞 / HDL新生 / アポAI / ABCAl / sphingomyelin / caveolin1 / apo E / acidic FGF / ニューロン / apo AI / apolipoprotein E / LDL / ホスファチジルコリン / Cholesterol efflux / Vascular smooth muscle cell / コレステロール引き出し / 血管平滑筋細胞 / マウス腹腔マクロファ-ジ / ディスコイダル HDL / アポリポタンパクA / ピレン / 脂質転送蛋白質活性化因子 / コレステロ-ル逆転送系 / ピレンーコレステロ-ル / ヘパリン静注後血漿リパーゼ活性 / トリグリセライド / カイロマイクロン / I型高リポ蛋白血症 / ABCG1 / caveolin-1 / urea / TICE / 小腸 / マウス / ABCトランスポーター / ファゴサイトーシス / phagocytosis / SAA Less

食品中の抗動脈硬化活性成分総合的研究
- Principal Investigator
  
  呂鋭
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chubu University
Studies on novel HDL cholesterol efflux mechanisms
- Principal Investigator
  
  辻田麻紀
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nagoya City University
Study on paradox between the trends in nutritional environment and plasma lipid parameters in JapanPrincipal Investigator
- Principal Investigator
  
  Yokoyama Shinji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chubu University
Nutritional Metabolic Regulation of HDL Focusing on Functional Foods
- Principal Investigator
  
  LU RUI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chubu University
Lipid nutrition and inflammatory response by ABC proteins
- Principal Investigator
  
  Abe-Dohmae Sumiko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chubu University
Molecular mechanism of HDL reduction in diabetic malnutrition
- Principal Investigator
  
  LU Rui
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Chubu University
Molecular Nutritional Regulation of Sterol Metabolism and AtherosclerosisPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shinji
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Chubu University
The new function of cave-in-1 in the ABCA1-mediated HDL biogenesis
- Principal Investigator
  
  LU Rui
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Chubu University
Nutritional regulation of sterol metabolism in development of lifestyle-related diseasesPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shinji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Chubu University
Studies of TICE and intesitinal SR-BI
- Principal Investigator
  
  TSUJITA Maki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
Roles of ABC transporters in cellular cholesterol transport and inflammatory response
- Principal Investigator
  
  ABE-DOHMAE Sumiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
HDL generation as an effector against inflammation and atherosclerosis
- Principal Investigator
  
  ABE-DOHMAE Sumiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
Mechanism of cellular cholesterol release
- Principal Investigator
  
  DOHMAE Sumiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
脳内HDLの機能;脳コレステロール輸送と障害の修復
- Principal Investigator
  
  伊藤仁一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya City University
Repair system against stress and injury in central nervous system
- Principal Investigator
  
  ITO Jinichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya City University
脳内HDLの機能:脳コレステロール輸送と障害の修復
- Principal Investigator
  
  伊藤仁一
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya City University
Elucidation of HDL generation mechanism in hepatocytes
- Principal Investigator
  
  TSUJITA Maki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
Molecular Basis of Intracellular Cholesterol Homeostasis and Genration of HDLPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shinji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
Mechanism of HDL Generation
- Principal Investigator
  
  ABE Sumiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
脳内HDLの機能;脳コレステロール代謝平衡と障害の修復Principal Investigator
- Principal Investigator
  
  横山信治
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya City University
脳内HDLの機能:脳ステロール代謝平衡と障害の修復Principal Investigator
- Principal Investigator
  
  横山信治
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya City University
Molecular Basis of Intracellular Cholesterol HomeostasisPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shiniji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
Mechanism of Cellular Cholesterol Release
- Principal Investigator
  
  ABE Sumiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nagoya City University
Mechanism for regulation of cholesterol metabolism of astrocite in central nervous system
- Principal Investigator
  
  ITO Jinichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya City University
Homeostasis and its pathology of cellular lipidPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shinji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya City University
Mechanism for cellular cholesterol remoral mediated by an apolipoprotein receptor(s)Principal Investigator
- Principal Investigator
  
  YOKOYAMA Sinji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya City University
Enhancement of cellular cholesterol efflux and atherosclerosis treatwent by pharmacological stimulation of an apolipoprotein receptor(s)Principal Investigator
- Principal Investigator
  
  YOKOYAMA Sinji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Nagoya City University
Function of astrocytes on cholesterol metabolism of central nervous system
- Principal Investigator
  
  ITO Jinchi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya City University
Reaction mechanism of cholesterol transport system
- Principal Investigator
  
  ICHIKAWA Yoshiyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagawa Medical School
Kinetics of cholesterol reverse transport system
- Principal Investigator
  
  ICHIKAWA Yoshiyuki, OHNISHI Taira
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagawa Medical School
本態性高脂血症の成因,特に脂質水解酵素と関連因子の変異に関する分子遺伝学的研究
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  National Cardiovascular Center Research Institute
Molecular Basis of the Etiology and Pathogenesis of Hyperlipoproteinemia
- Principal Investigator
  
  YAMAMOTO Akira
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  National Cardiovascular Center Research Institute (NCVC)
Physiological roles of non-polar lipid transfer reaction between plasma lipoproteins and the reaction mechanism of its catalyst protein.Principal Investigator
- Principal Investigator
  
  YOKOYAMA Shinji
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  National Cardiovascular Center

[Journal Article] Lipoprotein Particles in Cerebrospinal Fluid2024
- Author(s)
  Tsujita Maki、Melchior John T.、Yokoyama Shinji
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 44 Issue: 5 Pages: 1042-1052
- DOI
  10.1161/atvbaha.123.318284
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08631
[Journal Article] Vaccination against the HDL Receptor of S. japonicum Inhibits Egg Embryonation and Prevents Fatal Hepatic Complication in Rabbit Model2023
- Author(s)
  Jifeng Zhu, Lina Zhang, Zechao Xue, Zile Li, Chun Wang, Fanyan Chen, Yalin Li, Yang Dai, Yonghua Zhou, Sha Zhou, Xiaojun Chen, Kuniko Okumura-Noji, Rui Lu, Shinji Yokoyama, and Chuan Su
- Journal Title
  
  PLOS Neglected Tropical Diseases
  
  Volume: 17 Issue: 11 Pages: e0011749-e0011749
- DOI
  10.1371/journal.pntd.0011749
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11586
[Journal Article] Continuous and Marked Increase of Japanese HDL Associates Paradoxically with their Nutritional Shift2023
- Author(s)
  Shinji Yokoyama
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 30 Issue: 8 Pages: 919-933
- DOI
  10.5551/jat.63894
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2023-08-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11586
[Journal Article] 後発酵茶の糖質・脂質消化酵素に対する阻害作用2023
- Author(s)
  横山さや香, 渡邉章子, 安藤拓海, 牛丸日南子, 呂鋭, 呂暁華, 岡本威明, 田中守
- Journal Title
  
  日本末病学会雑誌
  
  Volume: 29 Pages: 9-15
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11591
[Journal Article] 後発酵茶の糖質・脂質消化酵素に対する阻害作用2023
- Author(s)
  横山さや香,渡邉章子,牛丸日南子,安藤拓海,太田鈴乃,呂鋭,香西はな,恋田彩加,田中守,
- Journal Title
  
  日本未病学会雑誌Vol.29 No.1
  
  Volume: 29 Pages: 9-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10811
[Journal Article] Expression of ATP-binding cassette transporter A1 is induced by nerve injury and its deficiency affects neurite tip morphology and elongation in cultured neurons2022
- Author(s)
  Nobue Shishioh, Sumiko Kiryu-Seo, Sumiko Abe-Dohmae, Shinji Yokoyama, Hiroshi Kiyama
- Journal Title
  
  Journal of Chemical Neuroanatomy
  
  Volume: 125 Pages: 102164-102174
- DOI
  10.1016/j.jchemneu.2022.102164
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07304, KAKENHI-PROJECT-21K19310, KAKENHI-PROJECT-19K11805, KAKENHI-PROJECT-23K24695
[Journal Article] Sichuan dark tea improves lipid metabolism and prevents aortic lipid deposition in diet-induced atherosclerosis model rats2022
- Author(s)
  Lu R, Sugimoto T, Tsuboi T, Sekikawa T, Tanaka M, Lyu X, Yokoyama S.
- Journal Title
  
  Fronteers in Nutrition
  
  Volume: 9 Pages: 1014883-1014883
- DOI
  10.3389/fnut.2022.1014883
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11586, KAKENHI-PROJECT-20K11591
[Journal Article] HDL Receptor in Schistosoma japonicum Mediating Egg Embryonation: Potential Molecular Basis for High Prevalence of Cholesteryl Ester Transfer Protein Deficiency in East Asia2022
- Author(s)
  Shinji Yokoyama
- Journal Title
  
  Front Cell Dev Biol
  
  Volume: 17
- DOI
  10.3389/fcell.2022.807289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11586
[Journal Article] Validation by HPLC analysis of new equations for estimating cholesterol in plasma lipoprotein subfractions2021
- Author(s)
  Yokoyama S, Remaley AT, Sampson M, Ai M and Okazaki M
- Journal Title
  
  BBA Molecular and Cell Biology of Lipid
  
  Volume: 1866 Issue: 9 Pages: 158986-158986
- DOI
  10.1016/j.bbalip.2021.158986
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11586
[Journal Article] ABCA7 links sterol metabolism to the host defense system: Molecular background for potential management measure of Alzheimer's disease2021
- Author(s)
  Sumiko Abe-Dohmae, Shinji Yokoyama
- Journal Title
  
  Gene
  
  Volume: 768 Pages: 145316-145316
- DOI
  10.1016/j.gene.2020.145316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11805
[Journal Article] Zinc Increases ABCA1 by Attenuating Its Clearance Through the Modulation of Calmodulin Activity2021
- Author(s)
  Rui Lu, Takahiro Ishikawa, Mamoru Tanaka, Tomoe Tsuboi, Shinji Yokoyama
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 28 Issue: 3 Pages: 261-270
- DOI
  10.5551/jat.55384
- NAID
  130007993133
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11591
[Journal Article] Molecular mechanism for nobiletin to enhance ABCA1/G1 expression in mouse macrophages.2020
- Author(s)
  Tsuboi T, Lu R, Yonezawa T, Watanabe A, Woo JT, Abe-Dohmae S, Yokoyama S.
- Journal Title
  
  Atherosclerosis
  
  Volume: 297 Pages: 32-39
- DOI
  10.1016/j.atherosclerosis.2020.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11805, KAKENHI-PROJECT-17K00892, KAKENHI-PROJECT-19K15778
[Journal Article] Selective correction of genotype yield by probucol in HDL-deficient mice propagation.2019
- Author(s)
  Tsujita M, Akita N, Yokota T, Kobayashi F, Yokoyama S.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 26
- NAID
  130007779024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02903
[Journal Article] Beneficial Effect of Retuning to “Japan Diet” for the Japanese2019
- Author(s)
  Yokoyama S.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 26 Issue: 1 Pages: 1-2
- DOI
  10.5551/jat.ED099
- NAID
  130007542020
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2019-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02903
[Journal Article] Application of the Japanese Guidelines for the Diagnosis of Familial Hypercholesterolemia in General Practice: It is to be Validated in International Harmonization2019
- Author(s)
  Tanaka N, Teramoto T, Yokoyama S.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 26 Issue: 1 Pages: 93-98
- DOI
  10.5551/jat.46979
- NAID
  130007542023
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2019-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02903
[Journal Article] Oxidation of methionine residues in human apolipoprotein A-I generates a potent pro-inflammatory molecule.2019
- Author(s)
  Witkowski A, Carta S, Lu R, Yokoyama S, Rubartelli A, Cavigiolio G.
- Journal Title
  
  J Biol Chem.
  
  Volume: 294 Issue: 10 Pages: 3634-3646
- DOI
  10.1074/jbc.ra118.005663
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02903, KAKENHI-PROJECT-17K00892
[Journal Article] AGE-albumin enhances ABCA1 degradation by ubiquitin-proteasome and lysosomal pathways in macrophages2018
- Author(s)
  Iborra Rodrigo Tallada、Machado-Lima Adriana、Okuda Ligia Shimabukuro、Pinto Paula Ramos、Nakandakare Edna Regina、Machado Ubiratan Fabres、Correa-Giannella Maria Lucia、Pickford Russell、Woods Tom、Brimble Margaret A.、Rye Kerry-Anne、Lu Rui、Yokoyama Shinji、Passarelli Marisa
- Journal Title
  
  Journal of Diabetes and its Complications
  
  Volume: 32 Issue: 1 Pages: 1-10
- DOI
  10.1016/j.jdiacomp.2017.09.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00892, KAKENHI-PROJECT-15H02903
[Journal Article] Trend of HDL increase among Japanese people continues in National Health and Nutrition Survey2018
- Author(s)
  Shinji Yokoyama
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 25 Issue: 6 Pages: 554-556
- DOI
  10.5551/jat.43646
- NAID
  130007382562
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2018-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02903
[Journal Article] ApoA-I/A-II-HDL positively associates with apoB-lipoproteins as a potential atherogenic indicator. Lipids in Health and Disorder.2017
- Author(s)
  Toshimi Kido, Kazuo Kondo, Hideaki Kurata, Yoko Fujiwara, Takeyoshi Urata, Hiroshige Itakura, Shinji Yokoyama
- Journal Title
  
  Lipids in Health and Disorder
  
  Volume: 16 Issue: 1 Pages: 225-225
- DOI
  10.1186/s12944-017-0619-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02903
[Journal Article] Exposure to High Glucose Concentration Decreases Cell Surface ABCA1 and HDL Biogenesis in Hepatocytes2017
- Author(s)
  Maki Tsujita, Mohammad Anwar Hossain, Rui Lu, Tomoe Tsuboi, Kuniko Okumura-Noji and Shinji Yokoyama
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 11 Pages: 1132-1149
- DOI
  10.5551/jat.39156
- NAID
  130006191604
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461370, KAKENHI-PROJECT-15H02903, KAKENHI-PROJECT-15K08615, KAKENHI-PROJECT-15K15349
[Journal Article] Methods for Monitoring ABCA1-Dependent Sterol Release2017
- Author(s)
  Yamauchi Y, Yokoyama S, Chang TY
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1583 Pages: 257-273
- DOI
  10.1007/978-1-4939-6875-6_19
- ISBN
  9781493968732, 9781493968756
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-16K08618, KAKENHI-PROJECT-15H02903
[Journal Article] Homogeneous Assays for LDL-C and HDL-C are Reliable in Both the Postprandial and Fasting State2017
- Author(s)
  Takashi Miida, Kunihiro Nishimura, Satoshi Hirayama, Yoshihiro Miyamoto, Masakazu Nakamura, Daisaku Masuda, Shizuya Yamashita, Shoji Ushiyama, Naohisa Fujita, Shinji Yokoyama, Tamio Teramoto
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 6 Pages: 583-599
- DOI
  10.5551/jat.40006
- NAID
  130005687828
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02903, KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-15K08624, KAKENHI-PROJECT-26461644
[Journal Article] Bioinformatic analysis of plasma apolipoproteins A-I and A-II revealed unique features of A-I/A-II HDL particles in human plasma.2016
- Author(s)
  Toshimi Kido, Hideaki Kurata, Kazuo Kondo, Hiroshige Itakura, Mitsuyo Okazaki, Takeyoshi Urata and Shinji Yokoyama
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1
- DOI
  10.1038/srep31532
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02903
[Journal Article] Caveolin-1 facilitates internalization and degradation of ABCA1 and probucol oxidative products interfere with this reaction to increase HDL biogenesis2016
- Author(s)
  Rui Lu, Tomoe Tsuboi, Kuniko Okumura-Noji, Noriyuki Iwamoto, and Shinji Yokoyama
- Journal Title
  
  Atherosclerosis
  
  Volume: 253 Pages: 54-60
- DOI
  10.1016/j.atherosclerosis.2016.08.025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02903, KAKENHI-PROJECT-26461370
[Journal Article] ABCA1-dependent sterol release: sterol molecule specificity and potential membrane domain for HDL biogenesis2016
- Author(s)
  Yamauchi Y, Yokoyama S, Chang TY.
- Journal Title
  
  J Lipid Res
  
  Volume: 57 Issue: 1 Pages: 77-88
- DOI
  10.1194/jlr.m063784
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-15H02903
[Journal Article] Probucol-Oxidized Products, Spiroquinone and Diphenoquinone, Promote Reverse Cholesterol Transport in Mice2016
- Author(s)
  Yakushiji E, Ayaori M, Nishida T, Shiotani K, Takiguchi S, Nakaya K, Uto-Kondo H, Ogura M, Sasaki M, Yogo M, Komatsu T, Lu R, Yokoyama S, Ikewaki K
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 36 Issue: 4 Pages: 591-597
- DOI
  10.1161/atvbaha.115.306376
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02903, KAKENHI-PROJECT-26461370, KAKENHI-PROJECT-16K09790
[Journal Article] ATP-binding Cassette Transporter A7 (ABCA7) Loss of Function Alters Alzheimer Amyloid Processing2015
- Author(s)
  Satoh, K. Abe-Dohmae, S. Yokoyama, S. St George-Hyslop, P. Fraser, P. E.
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 40 Pages: 24152-65
- DOI
  10.1074/jbc.m115.655076
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15H02903
[Journal Article] Preferential Incorporation of Shorter and Less Unsaturated Acyl Phospholipids into High Density Lipoprotein-Like Particles in the ABCA1- and ABCA7-mediated Biogenesis with apoA-I2015
- Author(s)
  Noriko Hotta, Sumiko Abe-Dohmae, Ryo Taguchi, and Shinji Yokoyama
- Journal Title
  
  Chemistry and Physics of Lipids
  
  Volume: 187 Pages: 1-9
- DOI
  10.1016/j.chemphyslip.2015.01.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24614018, KAKENHI-PROJECT-24619007, KAKENHI-PROJECT-25461375
[Journal Article] Prevention of fatal hepatic complication in schistosomiasis by inhibition of CETP2015
- Author(s)
  Yokoyama S, Okumura-Noji K, Lu R
- Journal Title
  
  J Biomed Res
  
  Volume: 29 Issue: 3 Pages: 176-188
- DOI
  10.7555/jbr.29.20150005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02903
[Journal Article] Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum2015
- Author(s)
  Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S.
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 39 Pages: 23464-23477
- DOI
  10.1074/jbc.m115.662668
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460385, KAKENHI-PROJECT-25461375, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-15H02500, KAKENHI-PROJECT-15H02903, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-15H04696
[Journal Article] Unique Features of High-Density Lipoproteins in the Japanese: In Population and in Genetic Factors2015
- Author(s)
  Shinji Yokoyama
- Journal Title
  
  Nutrients
  
  Volume: 7 Issue: 4 Pages: 2359-2381
- DOI
  10.3390/nu7042359
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24614018, KAKENHI-PROJECT-15H02903
[Journal Article] Apolipoprotein A-I induces tubulin phosphorylation in association with cholesterol release in fetal rat astrocytes2014
- Author(s)
  Jin-ichi Ito, Rui Lu, Yuko Nagayasu and Shinji Yokoyama
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1841 Issue: 9 Pages: 1234-1240
- DOI
  10.1016/j.bbalip.2014.04.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24614018
[Journal Article] A potential screening factor for accumulation of cholesteyl ester transfer protein deficiency in East Asia: Schistosoma japonicum2014
- Author(s)
  Yokoyama S.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1841 Issue: 4 Pages: 495-504
- DOI
  10.1016/j.bbalip.2013.12.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24614018
[Journal Article] Involvement of cdc42/Rho kinase in apoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes.2014
- Author(s)
  11. Kheirollah A., Nagayasu Y., Ueda H., Yokoyama S. Michikawa M. and Ito J.
- Journal Title
  
  J. Neurosci. Res.
  
  Volume: 92 Issue: 4 Pages: 455-463
- DOI
  10.1002/jnr.23324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590073, KAKENHI-PROJECT-24614018, KAKENHI-PROJECT-25461375
[Journal Article] High-density lipoprotein of Japanese has markedly increased over the past twenty years2014
- Author(s)
  Shinji Yokoyama, Hirotsugu Ueshima, Takashi Miida, Masakazu Nakamura, Koki Takata, Tatsuyuki Fukukawa, Takaaki Goto, Mariko Harada-Shiba, Michitaka Sano, Kiminori Kato, Kazuhiro Matsuda
- Journal Title
  
  J. Atheroscl. Thromb
  
  Volume: 21 Pages: 151-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24614018
[Journal Article] High-density lipoprotein of Japanese has markedly increased over the past twenty years. J. Atheroscl. Thromb.2014
- Author(s)
  Shinji Yokoyama, Hirotsugu Ueshima, Takashi Miida, Masakazu Nakamura, Koki Takata, Tatsuyuki Fukukawa, Takaaki Goto, Mariko Harada-Shiba, Michitaka Sano, Kiminori Kato, Kazuhiro Matsuda.
- Journal Title
  
  J. Atheroscl. Thromb.
  
  Volume: 21 Pages: 151-160
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24614018
[Journal Article] CD36-Related Protein in Schistosoma japonicum: Candidate mediator of selective cholesteryl ester uptake from high density lipoprotein for egg maturation.2013
- Author(s)
  Kuniko Okumura-Noji, Yutaka Miura, Rui Lu, Kiyoufmi Asai, Nobuo Ohta, Paul J. Brindley, and Shinji Yokoyama.
- Journal Title
  
  FASEB Journal
  
  Volume: 27 Issue: 3 Pages: 1236-1244
- DOI
  10.1096/fj.12-219816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24614018
[Journal Article] Enhancement of FGF-1 release along with cytosolic proteins from rat astrocytes by hydrogen peroxide.2013
- Author(s)
  Ito J, Nagayasu Y, Hoshikawa M, Kato KH, Miura Y, Asai K, Hayashi H, Yokoyama S, Michikawa M.
- Journal Title
  
  Brain Res.
  
  Volume: 1522 Pages: 12-21
- DOI
  10.1016/j.brainres.2013.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591509, KAKENHI-PROJECT-24614018, KAKENHI-PROJECT-25461375
[Journal Article] Defining Patients at Extremely High Risk for Coronary Artery Disease in Heterozygous Familial Hypercholesterolemia2012
- Author(s)
  Sugisawa T, Okamura T, Makino H, Watanabe M, Kishimoto I, Miyamoto Y, Iwamoto N, Yamamoto A, Yokoyama S, Harada-Shiba M
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 19 Issue: 4 Pages: 369-375
- DOI
  10.5551/jat.11536
- NAID
  130004444603
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390252, KAKENHI-PROJECT-22591004, KAKENHI-PUBLICLY-23122525, KAKENHI-PROJECT-24390174, KAKENHI-PROJECT-24614018
[Journal Article] Background to Discuss Guidelines for Control of Plasma HDL-Cholesterol in Japan*2012
- Author(s)
  Yokoyama S, Yamashita S, Ishibashi S, Sone H, Oikawa S, Shirai K, Ohta T, Bujo H, Kobayashi J, Arai H, Harada-Shiba M, Eto M, Hayashi T, Gotoda T, Suzuki H, Yamada N
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 19 Issue: 3 Pages: 207-212
- DOI
  10.5551/jat.11452
- NAID
  130004444591
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300227, KAKENHI-PROJECT-20406004, KAKENHI-PROJECT-21590762, KAKENHI-PROJECT-22591004, KAKENHI-PROJECT-24614018
[Journal Article] ABCA7: a potential mediator between cholesterol homeostasis and the host defense system.2012
- Author(s)
  Sumiko Abe-Dohmae, Shinji Yokoyama
- Journal Title
  
  Clinical Lipidology
  
  Volume: 7 Issue: 6 Pages: 677-687
- DOI
  10.2217/clp.12.67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24614018
[Journal Article] HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A72011
- Author(s)
  Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S
- Journal Title
  
  Atherosclerosis
  
  Volume: 217(2) Issue: 2 Pages: 407-414
- DOI
  10.1016/j.atherosclerosis.2011.06.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591164
[Journal Article] Impact of self-association on function of apolipoprotein A-I2011
- Author(s)
  Jayaraman S, Abe-Dohmae S, Yokoyama S, Cavigiolio G
- Journal Title
  
  J Biol Chem
  
  Volume: 286巻 Issue: 41 Pages: 35610-35623
- DOI
  10.1074/jbc.m111.262485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390188, KAKENHI-PROJECT-21591164
[Journal Article] Insulin Down-Regulates Specific Activity Of ATP-Binding Cassette Transporter A1 For High Density Lipoprotein Biogenesis Through Its Specific Phosphorylation2011
- Author(s)
  Kazuhiko N, Arai Y, Mitani H, Abe-Dohmae S, Yokoyama S
- Journal Title
  
  Atherosclerosis
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591164
[Journal Article] Calpain-mediated ABCA1 degradation : Post-translational regulation of ABCA1 for HDL biogenesis2011
- Author(s)
  Yokoyama S, Arakawa R, Wu CA, Iwamoto N, Lu R, Tsujita M, Abe-Dohmae S
- Journal Title
  
  Biochim Biophys Acta 2012 Mar
  
  Volume: 1821(3) Issue: 3 Pages: 547-551
- DOI
  10.1016/j.bbalip.2011.07.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591164, KAKENHI-PROJECT-23591338, KAKENHI-PROJECT-24614018
[Journal Article] Calpain-mediated ABCA1 degradation : Post-translational regulation of ABCA1 for HDL biogenesis2011
- Author(s)
  Yokoyama S, Arakawa R, Wu CA, Iwamoto N, Lu R, Tsujita M, Abe-Dohmae S
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1821(Review) Pages: 547-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591164
[Journal Article] Roles of ATP-Binding Cassette Transporter A7 in Cholesterol Homeostasis and Host Defense System2011
- Author(s)
  Tanaka N, Abe-Dohmae S, Iwamoto N, Yokoyama S
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 18 Issue: 4 Pages: 274-281
- DOI
  10.5551/jat.6726
- NAID
  130004845365
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390188, KAKENHI-PROJECT-21591164
[Journal Article] Roles of ATP-Binding Cassette Transporter A7 in Cholesterol Homeostasis and Host Defense System.2011
- Author(s)
  Tanaka N, Abe-Dohmae S, Iwamoto N, Yokoyama S.
- Journal Title
  
  J Atheroscler Thromb.
  
  Volume: (Review in press)
- NAID
  130004845365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591164
[Journal Article] ApoA-I enhances generation of HDL-like lipoproteins through interaction between ABCA1 and phospholipase Cγ in rat astrocytes2011
- Author(s)
  Ito J, Nagayasu Y, Kheirollah A, Abe-Dohmae S, Yokoyama S
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1811巻 Issue: 12 Pages: 1062-1069
- DOI
  10.1016/j.bbalip.2011.08.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390188, KAKENHI-PROJECT-21591164
[Journal Article] Insulin down-regulates specific activity of ATP-binding cassette transporter A1 for high density lipoprotein biogenesis through its specific phosphorylation2011
- Author(s)
  Nonomura K, Arai Y, Mitani H, Abe-Dohmae S, Yokoyama S
- Journal Title
  
  Atherosclerosis
  
  Volume: 216 Issue: 2 Pages: 334-341
- DOI
  10.1016/j.atherosclerosis.2011.02.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390188, KAKENHI-PROJECT-21591164
[Journal Article] Calmodulin Interacts With ATP Binding Cassette Transporter A1 to Protect From Calpain-Mediated Degradation and Upregulates High-Density Lipoprotein Generation2010
- Author(s)
  Iwamoto N, Lu R, Tanaka N, Abe-Dohmae S, Yokoyama S
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 30巻 Issue: 7 Pages: 1446-1452
- DOI
  10.1161/atvbaha.110.203927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390188, KAKENHI-PROJECT-21591164
[Journal Article] Calmodulin Interacts With ATP Binding Cassette Transporter A1 to Protect From Calpain-Mediated Degradation and Upregulates High-Density Lipoprotein Generation.2010
- Author(s)
  Iwamoto N, Lu R, Tanaka N, Abe-Dohmae S, Yokoyama S.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 30 Pages: 1446-1452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591164
[Journal Article] Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7.2010
- Author(s)
  Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S.
- Journal Title
  
  J Lipid Res.
  
  Volume: 51 Pages: 2591-2599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591164
[Journal Article] Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A72010
- Author(s)
  Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S
- Journal Title
  
  J Lipid Res
  
  Volume: 51巻 Issue: 9 Pages: 2591-2599
- DOI
  10.1194/jlr.m006049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390188, KAKENHI-PROJECT-21591164
[Journal Article] Pharmacological inhibition of ABC A1 degradation increases HDL biogenesis and exhibits antiatherogenesis2009
- Author(s)
  Arakawa R, Tsujita M, Iwamoto N, Ito-Ohsumi C, Lu R, Wu CA, Shimizu K, Aotsuka T, Kanazawa H, Abe-Dohmae S, Yokoyama S.
- Journal Title
  
  J Lipid Res.
  
  Volume: 50巻 Issue: 11 Pages: 2299-2305
- DOI
  10.1194/jlr.m900122-jlr200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390188, KAKENHI-PROJECT-21591164
[Journal Article] Involvement of protein kinase D in phosphorylation and increase of DNA binding of activator protein 2[alpha] to downregulate ATP-binding cassette transporter Al2008
- Author(s)
  Iwamoto N, Abe-Dohmae S, Rui L, and Yokoyama S
- Journal Title
  
  Arterioscler Thromb Vasc Biol 28
  
  Pages: 2282-2287
- Data Source
  KAKENHI-PROJECT-19591063
[Journal Article] The RXR agonists PA024 and HX630 have different abilities to activate LXR/RXR and to induce ABCA1 expression in macrophage cell lines2008
- Author(s)
  Nishimaki-Mogami T, Tamehiro N, Sato Y, Okuhira KI, Sai K, Kagechika H, Shudo K, Abe-Dohmae S, Yokoyama S, Ohno Y, Inoue K, and Sawada JI
- Journal Title
  
  Biochem Pharmacol 76
  
  Pages: 1006-1013
- Data Source
  KAKENHI-PROJECT-19591063
[Journal Article] Biogenesis of HDL by SAA is dependent on ABCA1 in the liver in vivo2008
- Author(s)
  Hu W, Abe-Dohmae S, Tsujita M, Iwamoto N, Ogikubo 0, Otsuka T, Kumon Y, and Yokoyama S
- Journal Title
  
  J Lipid Res 49
  
  Pages: 386-393
- Data Source
  KAKENHI-PROJECT-19591063
[Journal Article] Apolipoprotein A-I increases association of cytosolic cholesterol and caveolin-1 with microtubule-cytoskeletons in rat astrocytes.2006
- Author(s)
  Ito J, Kheirollh Alireza, Rui Lu, Kato K, Yokoyama S.
- Journal Title
  
  J.Neurochem. 97
  
  Pages: 1034-1043
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590839
[Journal Article] Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in amanner of autocrine action.2005
- Author(s)
  Ito J, Nagayasu Y, Lu R, Kheirollah A, Hayashi M, Yokoyama S.
- Journal Title
  
  J.Lipid Res. 46
  
  Pages: 679-686
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590839
[Journal Article] On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway.2005
- Author(s)
  Tsujita M, Wu CA, Abe-Dohmae S, Usui S, Okazaki M, Yokoyama S.
- Journal Title
  
  J Lipid Res. 46(1)
  
  Pages: 154-162
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway2005
- Author(s)
  辻田麻紀, 呉成愛, 堂前純子, 臼井真一, 岡崎三代, 横山信治
- Journal Title
  
  Journal of Lipid Reserach 46
  
  Pages: 154-162
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] An Inhibitor of acylCoA : cholesterol acyltransferase increases expression of ABC-binding cassett transporter AI and thereby enhances the ApoAI-mediated release of cholesterol from macrophages2004
- Author(s)
  杉本佳奈美, 辻田麻紀, 呉成愛, 鈴木和夫, 横山信治
- Journal Title
  
  Biochemica et Biophysica Acta 1636
  
  Pages: 69-76
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] Promoter polymorphism in fibroblast growth factor 1 gene increases risk of definite Alzheimer's disease.2004
- Author(s)
  Yamagata H, Chen Y, Akatsu H, Kamino K, Ito J, Yokoyama S, Yamagata T, Kosaka K, Miki T, Kondo I.
- Journal Title
  
  Biochem Biophys Res Commun 321
  
  Pages: 320-323
- Data Source
  KAKENHI-PROJECT-16015294
[Journal Article] Fibroblast growth factor 1 is produced prior to apolipoprotein E in the astrocytes after cryo-injury of mouse brain.2004
- Author(s)
  Tada T., Ito J., Asai M., Yokoyama S.
- Journal Title
  
  Neurochem. 45
  
  Pages: 23-30
- Data Source
  KAKENHI-PROJECT-16590839
[Journal Article] Apolipoprotein A-I induces translocation of protein kinase Ca to a cytosolic lipid-protein particle in astrocytes.2004
- Author(s)
  Ito J, Nagayasu Y, Kheirollah A, Yokoyama S.
- Journal Title
  
  J.Lipid Res 45
  
  Pages: 2269-2276
- Data Source
  KAKENHI-PROJECT-16590839
[Journal Article] Apolipoprotein A-I induces translocation of protein kinase Ca to a cytosolic lipid-protein particle in astrocytes.2004
- Author(s)
  Ito J, Nagayasu Y, Kheirollah A, Yokoyama S.
- Journal Title
  
  J.Lipid Res 45
  
  Pages: 2269-2276
- Data Source
  KAKENHI-PROJECT-16015294
[Journal Article] An inhibitor of acylCoA: cholesterol acyltransferase increases expression of ATP-binding cassette transporter A1 and thereby enhances the ApoA-I-mediated release of cholesterol from macrophages.2004
- Author(s)
  Sugimoto K, Tsujita M, Wu CA, Suzuki K, Yokoyama S.
- Journal Title
  
  Biochim Biophys Acta. 1636(1)
  
  Pages: 69-76
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] Potential involvement of dissociated apolipoprotein A-I in the ABCA1-dependent cellular lipid release by high density lipoprotein.2004
- Author(s)
  Okuhira K, Tsujita M, Yamauchi Y, Abe-Dohmae S, Kato K, Handa T, Yokoyama S.
- Journal Title
  
  J Lipid Res. 45(4)
  
  Pages: 645-652
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] Probucol Inactivates ABCA1 in the Plasma Membrane with Respect to Its Mediation of Apolipoprotein Binding and High Density Lipoprotein Assembly and to Its Proteolytic Degradation2004
- Author(s)
  呉成愛, 辻田麻紀, 林弥智, 横山信治
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 30168-30174
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] Promoter polymorphism in fibroblast growth factor 1 gene increases risk of definite Alzheimer's disease.2004
- Author(s)
  Yamagata H, Chen Y, Akatsu H, Kamino K, Ito J, Yokoyama S, Yamagata T, Kosaka K, Miki T, Kondo I.
- Journal Title
  
  Biochem Biophys Res Commun 321
  
  Pages: 320-323
- Data Source
  KAKENHI-PROJECT-16590839
[Journal Article] Fibroblast growth factor 1 is produced prior to apolipoprotein E in the astrocytes after cryo-iniury of mouse brain.2004
- Author(s)
  Tada T., Ito J., Asai M., Yokoyama S.
- Journal Title
  
  Neurochem.Int. 45
  
  Pages: 23-30
- Data Source
  KAKENHI-PROJECT-16015294
[Journal Article] Probucol inactivates ABCA1 in the plasma membrane with respect to its mediation of apolipoprotein binding and high density lipoprotein assembly and to its proteolytic degradation.2004
- Author(s)
  Wu CA, Tsujita M, Hayashi M, Yokoyama S.
- Journal Title
  
  J Biol Chem. 279(29)
  
  Pages: 30168-30174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL2004
- Author(s)
  奥平桂一郎, 辻田麻紀, 山内祥生, 堂前純子, 加藤幸一, 半田哲夫, 横山信治
- Journal Title
  
  Journal of Lipid Research 45
  
  Pages: 645-652
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] 低HDL血症マウスにおけるストレス時の糖質コルチコイド産生抑制2003
- Author(s)
  辻田麻紀, 呉成愛, 横山信治
- Journal Title
  
  名古屋市立大医学会雑誌 54
  
  Pages: 155-165
- NAID
  110007391179
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] 低HDL血症マウスにおけるストレス時の糖質コルチコイド産生抑制2003
- Author(s)
  辻田麻紀, 呉成愛, 横山信治
- Journal Title
  
  名古屋市立大学医学会雑誌 54
  
  Pages: 155-165
- NAID
  110007391179
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] Stress-mediated corticosterone synthesis is defective in low plasma HDL mouse.2003
- Author(s)
  Maki Tsujita, Cheng-ai Wu, Shinji Yokoyama
- Journal Title
  
  Nagoyashiritudaigaku igakukaizasshi 54
  
  Pages: 155-165
- NAID
  110007391179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590952
[Journal Article] Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in a manner of autocrine action.
- Author(s)
  Ito J, Nagayasu Y, Lu R, Kheirollah A, Hayashi M, Yokoyama S.
- Journal Title
  
  J.Lipid Res. (in press)
- Data Source
  KAKENHI-PROJECT-16015294
[Journal Article] Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in a manner of autocrine action.
- Author(s)
  Ito J, Nagayasu Y, Lu R, Kheirollah A, Hayashi M, Yokoyama S
- Journal Title
  
  J.Lipid Res. (in press)
- Data Source
  KAKENHI-PROJECT-16590839
[Journal Article] Apolipoprotein A-I increases association of cytosolic cholesterol and caveolin-1 with microtubule-cytoskeletons in rat astrocytes.
- Author(s)
  Ito J, Kheirollh Alireza, Rui Lu, kato K, Yokoyama S.
- Journal Title
  
  J.Neurochem. (In press)
- Data Source
  KAKENHI-PROJECT-16590839
[Presentation] 柑橘類フラボノイドタンゲレチン・シネンセチンによるHDL産生促進2023
- Author(s)
  笠原涼佑、花田桃子、米澤貴之、禹済泰、横山信治、呂鋭
- Organizer
  第45回日本臨床栄養学会総会　第44回日本臨床栄養協会総会
- Data Source
  KAKENHI-PROJECT-23K10811
[Presentation] SR-BI 欠損マウスは遊離コレステロールに富む大型 HDL が上昇する2023
- Author(s)
  辻田麻紀、中須賀公亮、横山信治
- Organizer
  第161回日本循環器学会東海地方会
- Data Source
  KAKENHI-PROJECT-22K08631
[Presentation] Rumex japonicusに含まれるポリフェノール(Nepodin)によるABCA1/ABCG1発現・活性制御2023
- Author(s)
  関川達志、和田敢斗、前野善孝、米澤貴之、禹済泰、横山信治、呂鋭
- Organizer
  第45回日本臨床栄養学会総会　第44回日本臨床栄養協会総会
- Data Source
  KAKENHI-PROJECT-23K10811
[Presentation] 多価不飽和脂肪酸(PUFA)によるHDL産生への影響2023
- Author(s)
  佐藤優芽花、横山信治、呂鋭
- Organizer
  第45回日本臨床栄養学会総会　第44回日本臨床栄養協会総会
- Data Source
  KAKENHI-PROJECT-23K10811
[Presentation] ApoA-I/SR-BI double knockout mice plasma is rich in very large HDL with high free cholesterol2023
- Author(s)
  Maki Tsujita, Kosuke Nakasuka, Hiroshi Takase, Mayuko Kamiya, Chieko Mineo, Phillp W Shaul, Keiichiro Okuhira, Shinji Yokoyama, Alan T Remaley
- Organizer
  Vascular Discovery 2023: From Genes to Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08631
[Presentation] プロポリス抽出物(Baccharin)によるHDL代謝制御について2023
- Author(s)
  足立早希、織田彩乃、米澤　貴之、禹済秦、横山信治、呂　鋭
- Organizer
  第45回日本臨床栄養学会総会　第44回日本臨床栄養協会総会
- Data Source
  KAKENHI-PROJECT-23K10811
[Presentation] マウスは高コレステロール飼料を嗜好するが高齢マウスではその嗜好が消失する2023
- Author(s)
  辻田麻紀、山本惇貴、奥平桂一郎、横山信治、鵜川眞也
- Organizer
  第55回日本動脈硬化学会総会
- Data Source
  KAKENHI-PROJECT-22K08631
[Presentation] Contents and food functions of catechins and free amino acids in microorganism-fermented teas2022
- Author(s)
  Watanabe A, Yokoyama S, Kusano Y, Kozai H, Lyu X, Lu R, Tanaka M
- Organizer
  IUNS-ICN 22nd International Congress of Nutrition in Tokyo, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11591
[Presentation] タンゲレチンによるABCA1・ABCG1活性制御の分子機構2022
- Author(s)
  呂鋭、花田桃子、米澤貴之、禹済泰、横山信治
- Organizer
  第54回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K11591
[Presentation] 後発酵茶の糖質・脂質消化酵素に対する阻害作用2022
- Author(s)
  横山さや香, 渡邉章子, 安藤拓海, 牛丸日南子, 呂鋭, 呂暁華, 岡本威明, 田中守
- Organizer
  第69回日本栄養改善学会学術総会，岡山
- Data Source
  KAKENHI-PROJECT-20K11591
[Presentation] 摂餌誘導性動脈硬化モデルにおける四川黒茶の脂質代謝とアテローム性動脈硬化症に対する効果2022
- Author(s)
  呂鋭、杉本拓海、坪井知恵、関川達志、田中守、呂暁華、横山信治
- Organizer
  第４４回日本臨床栄養学会総会　第４３回日本臨床栄養協会総会
- Data Source
  KAKENHI-PROJECT-20K11591
[Presentation] Heterogeneity of HDL: What should be a target ?2021
- Author(s)
  Yokoyama, Shinji
- Organizer
  International Symposium on Atherosclerosis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11586
[Presentation] 摂餌誘導性動脈硬化モデルにおける四川黒茶の脂質代謝とアテローム性動脈硬化症に対する効果2021
- Author(s)
  呂鋭、杉本拓海、坪井知恵、関川達志、田中守、呂暁華、横山信治
- Organizer
  第５3回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K11591
[Presentation] Sichuan Dark Tea improves Lipid Metabolism and Prevents Atherosclerosis in Diet-Induced Atherosclerosis Model Rats.2021
- Author(s)
  Rui Lu, Takumi Sugimoto, Tomoe Tsuboi, Tatsushi Sekikawa, Mamoru Tanaka1, Xiaohua, Shinji Yokoyama
- Organizer
  ISA2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11591
[Presentation] 柑橘類果皮由来機能性成分ノビレチンのHDL産生促進の分子機構2021
- Author(s)
  坪井知恵、呂鋭、米澤貴之、渡辺章夫、禹済泰、堂前純子、横山信治
- Organizer
  第５3回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K11591
[Presentation] 柑橘類果皮由来機能性成分ノビレチンによるステロール代謝の制御2019
- Author(s)
  坪井知恵, 呂鋭, 米澤貴之, 渡辺章夫, 禹済泰, 堂前純子, 横山信治
- Organizer
  日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-19K11805
[Presentation] Molecular mechanism of promotion of HDL production by Nobiletin, a functional ingredient in citrus peel2019
- Author(s)
  Tomoe Tsuboi, Rui Lu, Takayuki Yonezawa, Akio Watanabe, Je-Tae Woo, Sumiko Dohmae, Shinji Yokoyama
- Organizer
  2019 High Density Lipoprotein (HDL) Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11805
[Presentation] 亜鉛によるABCA1発現・活性への制御機序2019
- Author(s)
  呂鋭、石河　貴大、横山　信治
- Organizer
  第５１回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K00892
[Presentation] Zinc ion regulates ABCA1 by modulating calmodulin activity2019
- Author(s)
  Lu Rui, Ishikawa Takahiro, Yokoyama Shinji
- Organizer
  International Atherosclerosis Society: HDL workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00892
[Presentation] 柑橘類果皮由来機能性成分ノビレチンのHDL産生促進の分子機構2019
- Author(s)
  坪井知恵、呂鋭、米澤貴之、渡辺章夫、禹済泰、堂前純子、横山信治
- Organizer
  第４１回日本臨床栄養学会総会　第４０回日本臨床栄養協会総会
- Data Source
  KAKENHI-PROJECT-17K00892
[Presentation] ノビレチンのHDL産生促進の分子機構2019
- Author(s)
  坪井知恵, 呂鋭, 米澤貴之, 渡辺章夫, 禹済泰, 堂前純子, 横山信治
- Organizer
  ノビレチン研究会
- Data Source
  KAKENHI-PROJECT-19K11805
[Presentation] 柑橘類果皮由来機能性成分ノビレチンによるABCA1・ABCG1活性制御2019
- Author(s)
  坪井知恵, 呂鋭, 米澤貴之, 渡辺章夫, 禹済泰, 堂前純子, 横山信治
- Organizer
  日本動脈硬化学会
- Data Source
  KAKENHI-PROJECT-19K11805
[Presentation] Molecular mechanism for a functional ingredient in citrus peel nobiletin to enhance production of HDL2019
- Author(s)
  Tsuboi Tomoe、Lu Rui、Yonezawa Takayuki、Watanabe Akio、Woo Je-Tae、Abe-Dohmae Sumiko、Yokoyama Shinji
- Organizer
  International Atherosclerosis Society: HDL workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00892
[Presentation] High D-glucose level reduced distribution of ABCA1 on plasma membrane and reduced HDL assembly in liver cells.2018
- Author(s)
  M. Tsujita, Lu, R Tsuboi, Okumura-Noji, Hossain, Yokoyama
- Organizer
  7th FEBS Special Meeting on ABC Proteins
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00892
[Presentation] Exposure to High Glucose Concentration Decreases Cell Surface ABCA1 and HDL Biogenesis in Hepatocytes2017
- Author(s)
  Tsujita M, Hossain MA, Lu R, Tsuboi T, Okumura-Noji K, Yokoyama S.
- Organizer
  第49回　日本動脈硬化学会
- Data Source
  KAKENHI-PROJECT-17K00892
[Presentation] ABCA1分解による活性制御と無機栄養因子による調節2015
- Author(s)
  石河貴大、呂鋭、横山信治
- Organizer
  第37回日本臨床栄養学会総会　第36回日本臨床栄養協会総会
- Place of Presentation
  都市センターホテル　東京都千代区
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26461370
[Presentation] 膜蛋白質機能制御の新規薬剤標的としてのカベオリン－1相互作用2015
- Author(s)
  呂鋭、山口知恵、野路久仁子、横山信治
- Organizer
  第47回日本動脈硬化学会総会・学術集会
- Place of Presentation
  仙台国際センター　宮城県　仙台市
- Year and Date
  2015-07-08
- Data Source
  KAKENHI-PROJECT-26461370
[Presentation] ABCA1分解による活性制御と無機栄養因子による調節2015
- Author(s)
  石河貴大、呂鋭、横山信治
- Organizer
  第47回日本動脈硬化学会総会・学術集会
- Place of Presentation
  仙台国際センター　宮城県　仙台市
- Year and Date
  2015-07-08
- Data Source
  KAKENHI-PROJECT-26461370
[Presentation] ABCG1 null and SR-BI null mice reduced plasma HDL uptake by liver and small intestine.2014
- Author(s)
  Maki Tsujita, Nobukatsu Akita, M Anwar Hossain, Tomo Yokota, Alan T Remaley, Natsuko Kumamoto, Takashi Ueda, Shinya Ugawa, Shinji Yokoyama
- Organizer
  ATVB 2014 Scientific Sessions
- Place of Presentation
  Sheraton Centre Toronto Hotel, Toronto, Ontario, Canada
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] 栄養因子としてのコレステロールと動脈硬化の発症2014
- Author(s)
  横山信治
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  札幌市教育会館、札幌
- Year and Date
  2014-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-24614018
[Presentation] 我が国を含む東アジアにおけるCETP欠損症高頻度発症のスクリーニング因子：日本住血吸虫症2014
- Author(s)
  横山信治
- Organizer
  日本動脈硬化学会
- Place of Presentation
  京王プラザホテル、東京
- Year and Date
  2014-07-11
- Invited
- Data Source
  KAKENHI-PROJECT-24614018
[Presentation] Probucol oxidized products, spiroquinone and diphenoquinone promote reverse cholesterol transport in mice2014
- Author(s)
  M. Ayaori, E. Yakushiji, S. Takiguchi, H. Uto-Kondo, M. Sasaki, M. Yogo, T. Komatsu, L. Ru, S. Yokoyama, K. Ikewaki
- Organizer
  European Society of Cardiology Congress
- Place of Presentation
  Barcelona (Spain)
- Year and Date
  2014-09-01
- Data Source
  KAKENHI-PROJECT-24614018
[Presentation] A Screening Factor for High Prevalence of CETP Deficiency in East Asia: Schistosoma japonicum2014
- Author(s)
  S. Yokoyama
- Organizer
  Canadian Lipoprotein Conference
- Place of Presentation
  Saskatoon (Canada)
- Year and Date
  2014-10-04
- Invited
- Data Source
  KAKENHI-PROJECT-24614018
[Presentation] CETP欠損症の日本住血吸虫感染抵抗性2013
- Author(s)
  横山信治、野路久仁子、三浦裕、浅井清文、太田伸生、Paul J. Brindley
- Organizer
  日本脂質生化学会
- Place of Presentation
  宮城県松島市、ホテル大観荘
- Data Source
  KAKENHI-PROJECT-24614018
[Presentation] 日本人のHDLコレステロール測定値の長期上昇傾向について2013
- Author(s)
  横山信治、上島弘嗣、三井田孝、高田耕基、福川辰之、五藤孝秋、中村雅一、斯波真理子
- Organizer
  日本動脈硬化学会
- Place of Presentation
  東京都、京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24614018
[Presentation] ABCA1の分解調節によるHDL産生機構の制御2013
- Author(s)
  呂鋭、野路久仁子、横山　信治
- Organizer
  日本生化学会
- Place of Presentation
  神奈川県横浜市、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24614018
[Presentation] CETP欠損症の日本住血吸虫感染抵抗性2013
- Author(s)
  横山信治、野路久仁子、三浦裕、浅井清文、太田伸生、Paul J. Brindley
- Organizer
  日本動脈硬化学会
- Place of Presentation
  東京都、京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24614018
[Presentation] 高グルコースにより誘発される低HDL産生の分子制御機構の解明High D-glucose reduced apoA-I and HDL generation in liver cells.2012
- Author(s)
  辻田麻紀、秋田展克、横山信治、野路久仁子、道川　誠
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡)
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] PI3 kinase negatively regulates apolipoprotein-dependent HDL generation2012
- Author(s)
  Sumiko Abe-Dohmae, Yoshitaka Nobukuni, Narehiko Hayashi, Yoshiaki Marumo, Jyunko Masumoto, Shinji Yokoyama
- Organizer
  HDL Satellite for ISA 2012
- Place of Presentation
  Hilton Cairns Hotel (Australia)
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] An anion-exchange chromatography isolated sub-fraction of mouse apolipoprotein A-I is unable to activate cellular cholesterol release from mouse peritoneal macrophage foam cells.2012
- Author(s)
  Okumura-Noji Kuniko, Cavigiolio Giorgio, Huang Rong, Davidson W Sean, Akita Nobukatsu, Okuhira Kei-ichiro, Yokoyama Shinji, Tsujita Maki.
- Organizer
  Arteriosclerosis, Thrombosis and Vascular Biology 2012 Scientific Sessions
- Place of Presentation
  Hilton Chicago, Chicago, Il, USA.
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] Stress-mediated acute corticosterone production is depending on plasma HDL level but not long-term stress response in mice.2012
- Author(s)
  Maki Tsujita, Nobukatsu Akita, M Anwar Hossain, Frank J Gonzalez, Shinji Yokoyama, and Makoto Michikawa
- Organizer
  The 50th Anniversary Symposium on Cytochrome P450 in Fukuoka
- Place of Presentation
  Kyushu University Center-I for Collaborative Research, Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] Heterogeneity of human and mouse apolipoprotein A-I fractioned revealed by ion-exchange chromatography.2012
- Author(s)
  Okumura-Noji K, Huang R, Akita N, Remaley AT, Gonzalez FJ, Yokoyama S, Davidson WS , Tsujita M.
- Organizer
  International Symposium on Atherosclerosis Satellite Symposium High Density Lipoproteins: biology and therapeutics
- Place of Presentation
  Hilton Hotel Cairns, Cairns, TNQ, Australia
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] HMG-CoA Reductase Inhibitors Enhance Phagocytosis by Up-regulating ABCA72012
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama
- Organizer
  International Symposium on Atherosclerosis (ISA)
- Place of Presentation
  Sydney Convention and Exhibition Centre (Australia)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] Plasma prebeta-HDL in hypo-, normal- and hyper-alphalipoproteinemia model mice2012
- Author(s)
  Tomo Yokota, Kuniko Okumura-Noji, Nobukatsu Akita, Giorgio Cavigiolio, Alan T Remaley, Maki Tsujita, Shinji Yokoyama
- Organizer
  4th FEBS Special Meeting, ATP-binding Cassette(ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] PI3 kinase inhibits HDL generation through reducing protein levels of ABCA1 and ABCA72012
- Author(s)
  Sumiko Abe-Dohmae, Yoshitaka Nobukuni, Narehiko Hayashi, Yoshiaki Marumo, Jyunko Masumoto, Shinji Yokoyama
- Organizer
  International Symposium on Atherosclerosis (ISA)
- Place of Presentation
  Sydney Convention and Exhibition Centre (Australia)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] PI3 kinase inhibits ABCA1- and ABCA7-mediated HDL generation through reducing their protein levels2011
- Author(s)
  Sumiko Abe-Dohmae, Yoshitaka Nobukuni, Narehiko Hayashi, Yoshiaki Marumo, Jyunko Masumoto, Shinji Yokoyama
- Organizer
  第43回日本動脈硬化学会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] A Molecular Ground for Enhancement of the Host-Defense System by Statins2011
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Shinji Yokoyama
- Organizer
  第75回日本循環器学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-08-03
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] PI3キナーゼによるアポリポタンパク質依存性HDL新生反応の制御2011
- Author(s)
  堂前純子、信國好俊、林希彦、丸茂義晃、升本順子、横山信治
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] PKD/AP2によるABCA1とadiponectinの遺伝子発現の共通情報伝達系2011
- Author(s)
  岩本紀之、堂前純子、横山信治
- Organizer
  第53回日本脂質生化学会
- Place of Presentation
  ホテル東京ガーデンパレス(東京都)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] Characterization of ion-exchange column fractionated human and mouse apoA-I subfractions.2011
- Author(s)
  Kuniko Okumura-Noji, Toshihiko Usami, Giorgio Cavigiolio, Rong Huang, W Sean Davidson, Shinji Yokoyama, Maki Tsujita.
- Organizer
  Arteriosclerosis, Thrombosis and Vascular Biology 2011 Scientific Sessions
- Place of Presentation
  Chicago, Il, USA
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] Statin enhances phagocytosis by up-regulating ABCA72011
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama
- Organizer
  第43回日本動脈硬化学会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] 尿素ポリアクリルアミド電気泳動法を用いたヒト並びにマウス血漿apoA-Iの解析/ Analyses of human and mouse apo A-I in 6M Urea PAGE2011
- Author(s)
  辻田麻紀、宇佐美寿彦、秋田展克、Frank J Gonzalez、横山信治、野路久仁子
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] Mechanism of Lowering HDL Biosynthesis in Hyperinsulinemia States Through Direct Modulation of ATP-Binding Cassette Transporter A1 by Insulin Signaling2010
- Author(s)
  Kazuhiko Nonomura, Yoshie Arai, Hironobu Mitani, Sumiko Abe-Dohmae, Shinji Yokoyama
- Organizer
  第42回日本動脈硬化学会
- Place of Presentation
  岐阜長良国際会議場
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] Helical Apolipoproteins of High-Density Lipoprotein Enhance Phagocytesis by Stabilizing ATP-Binding Cassette Transporter A72010
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama
- Organizer
  第42回日本動脈硬化学会
- Place of Presentation
  岐阜長良国際会議場(若手研究者奨励賞)
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] Helical Apolipoproteins of High-Density Lipoprotein Enhance Phagocytos is by Stabilizing ATP-Binding Cassette Transporter A72010
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama
- Organizer
  The 6th International Atherosclerosis Society-sponsored Workshop on High Density Lipoproteins
- Place of Presentation
  Wistler, Canada
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] Amyloid A amyloidosis can be induced without SAA-HDL formation or substantial elevation of plasma SAA2010
- Author(s)
  W Hu, S Abe-Dohmae, Y Kumon, M Furihata, Y Hoshi, T Sugiura, O Ogikubo, T Otsuka, S Yokoyama
- Organizer
  The 6th International Atherosclerosis Society-sponsored Workshop on High Density Lipoproteins
- Place of Presentation
  Wistler, Canada
- Year and Date
  2010-05-18
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ABCA72010
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama
- Organizer
  第83回日本生化学会(ワークショップ)
- Place of Presentation
  神戸神戸国際会議場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] ABCA1 and serum amyloid A during acute and chronic inflammation2010
- Author(s)
  Sumiko Abe-Dohmae, Wei Hu, Shinji Yokoyama
- Organizer
  第42回日本動脈硬化学会(シンポジウム)
- Place of Presentation
  岐阜長良国際会議場
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] ABC transporter ABCA1 facilitates bidirectional sterol movement and modulates the regulatory sterol signals2010
- Author(s)
  Yoshio Yamauchi, Sumiko Abe-Dohmae, Shinji Yokoyama, Koichi Furukawa, Ta-Yuan Chang
- Organizer
  第42回日本動脈硬化学会
- Place of Presentation
  岐阜長良国際会議場
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ABCA72010
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama
- Organizer
  第83回日本生化学会
- Place of Presentation
  神戸神戸国際会議場
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] A new insight of the relation between cholesterol homeostasis and host defense system2010
- Author(s)
  Nobukiyo Tanaka, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Michael L.Fitzgerald, Shinji Yokoyama
- Organizer
  第42回日本動脈硬化学会
- Place of Presentation
  岐阜長良国際会議場(シンポジウム)
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21591164
[Presentation] ABCA1ノックアウトマウス由来線維芽細胞株の樹立とその特性の解析2008
- Author(s)
  堂前純子、黒野智恵子、西本静香、横山信治
- Organizer
  日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19591063
[Presentation] ABCA1とHDLコレステロール2008
- Author(s)
  堂前純子, 横山信治
- Organizer
  日本動脈硬化学会
- Place of Presentation
  つくば
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19591063
[Presentation] ABCA1ノックアウトマウスを用いたSAA-HDL産生機構の解析2008
- Author(s)
  胡魏, 堂亘遜虹丘, 岩本紀之, 公文義雄, 辻田麻紀, 横山信治
- Organizer
  日本生化学会中部支部会
- Place of Presentation
  岐阜
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19591063
[Presentation] Serum amyloid A secretion from hepatocytes and ABCA12007
- Author(s)
  Wei Hu, Sumiko Abe-Dohmae, Noriyuki Iwamoto, Yoshitaka Kumon, Maki Tsujitaand Shinji Yokoyama
- Organizer
  日本動脈硬化学会
- Place of Presentation
  大阪
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-19591063
[Presentation] 急性炎症期のS晶産生2007
- Author(s)
  胡魏, 堂前純子, 岩本紀之, 荻久保修, 大塚隆信, 横山信治
- Organizer
  血中濃度上昇とABCA1
- Place of Presentation
  浜松
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19591063
[Presentation] Modulation of HDL Biogenesis Through Regulation of ABCA1 Degradation: Involvement of Caveolin-1
- Author(s)
  呂　鋭、　横山　信治
- Organizer
  日本動脈硬化学会
- Place of Presentation
  京王プラザホテル　東京新宿区
- Year and Date
  2014-07-08 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-26461370
[Presentation] 血漿HDL－コレステロールの小腸への搬出はSR-BIを介する
- Author(s)
  Maki Tsujita, Tomo Yokota, Frank J Gonzalez, Shinya Ugawa, Shinji Yokoyama
- Organizer
  第87回日本生化学会
- Place of Presentation
  国立京都国際会館 (京都府・京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-23591338
[Presentation] ABCG1 null and SR-BI null mice reduced plasma HDL uptake by liver and small intestine.
- Author(s)
  Maki Tsujita, Nobukatsu Akita, M Anwar Hossain, Tomo Yokota, Alan T Remaley, Natsuko Kumamoto, Takashi Ueda, Shinya Ugawa, Shinji Yokoyama.
- Organizer
  Arteriosclerosis, Thrombosis and Vascular Biology 2014 Scientific Sessions
- Place of Presentation
  Toronto (Canada)
- Year and Date
  2014-05-01 – 2014-05-03
- Data Source
  KAKENHI-PROJECT-23591338
[]
[]

1. ABE-DOHMAE Sumiko (70227700)

# of Collaborated Projects: 18 results

# of Collaborated Products: 50 results
2. ITO Jinichi (60167260)

# of Collaborated Projects: 12 results

# of Collaborated Products: 11 results
3. TSUJITA Maki (10253262)

# of Collaborated Projects: 12 results

# of Collaborated Products: 25 results
4. LU Rui (80381862)

# of Collaborated Projects: 7 results

# of Collaborated Products: 37 results
5. YAMAMOTO Akira (00028408)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. YAMAMURA Taku (20132938)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. ICHIKAWA Yoshiyuki (60028355)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. OHNISHI Taira (50211107)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. IKEDA Yasuyuki (90176107)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 高木敦子 (90179416)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 田中守 (00612350)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
12. KURONO Chieko (50080049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. UGAWA Shinya (20326135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. OKAZAKI Mitsuyo (20013998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. TAJIMA Shoji (50132931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MIYAKE Yasuko (00132936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 高市成子 (00093930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中川大 (40397039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 堤内要 (50329851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 奥平桂一郎 (10425671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. AOTSUKA Tomoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 原斉

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. IKEJIMA Nobue

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. YAMAUCHI Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
25. 上田浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 古川鋼一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. CHANG Ta-Yuan Chang

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
28. 浅井清文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOKOYAMA Shinji 横山 信治

YAKOYAMA Shinji

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Study on paradox between the trends in nutritional environment and plasma lipid parameters in JapanPrincipal Investigator

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Molecular Nutritional Regulation of Sterol Metabolism and AtherosclerosisPrincipal Investigator

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Nutritional regulation of sterol metabolism in development of lifestyle-related diseasesPrincipal Investigator

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YOKOYAMA Shinji 横山信治